Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionG protein-coupled receptor activity

ADORA2A ADRA1A GPR19 OR6B3 OR1I1 APLNR OR2C3 ADGRV1 OR2F1 GPR162 CHRM5 GRPR ADGRG4

1.05e-058847013GO:0004930
GeneOntologyMolecularFunctioncalmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity

PDE1A PDE1C

3.63e-053702GO:0048101
GeneOntologyMolecularFunctioncalmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity

PDE1A PDE1C

3.63e-053702GO:0004117
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

ADORA2A ADRA1A GPR19 OR6B3 OR1I1 APLNR PKD1 OR2C3 FCRL5 ADGRV1 OR2F1 GPR162 CHRM5 GRPR ADGRG4

5.64e-0513537015GO:0004888
GeneOntologyMolecularFunctionABC-type peptide transporter activity

ABCB8 TAP2

7.24e-054702GO:0015440
GeneOntologyMolecularFunctiontransporter activity

SFXN4 KCNT2 SLC12A4 GSDMD ABCB8 SLC22A11 SLC6A19 PKD1 SLC6A15 ATP10B SLC13A3 SLCO6A1 TAP2 CHRM5

1.30e-0412897014GO:0005215
GeneOntologyMolecularFunctiontransmembrane transporter activity

SFXN4 KCNT2 SLC12A4 GSDMD ABCB8 SLC22A11 SLC6A19 PKD1 SLC6A15 SLC13A3 SLCO6A1 TAP2 CHRM5

2.04e-0411807013GO:0022857
GeneOntologyMolecularFunctionactive transmembrane transporter activity

SLC12A4 ABCB8 SLC22A11 SLC6A19 SLC6A15 SLC13A3 SLCO6A1 TAP2

2.58e-04477708GO:0022804
GeneOntologyMolecularFunctionaspartic-type endopeptidase activity

PGA4 PGA5 PGA3

2.94e-0437703GO:0004190
GeneOntologyMolecularFunctionaspartic-type peptidase activity

PGA4 PGA5 PGA3

3.19e-0438703GO:0070001
GeneOntologyMolecularFunctionphosphoric diester hydrolase activity

PDE1A PDE1C PLCH1 CHRM5

3.75e-0497704GO:0008081
GeneOntologyMolecularFunctionpeptide transmembrane transporter activity

ABCB8 TAP2

4.29e-049702GO:1904680
GeneOntologyMolecularFunctionsecondary active transmembrane transporter activity

SLC12A4 SLC22A11 SLC6A19 SLC6A15 SLC13A3 SLCO6A1

5.97e-04296706GO:0015291
GeneOntologyMolecularFunctioncalmodulin binding

ADORA2A PDE1A PDE1C AEBP1 AKAP12

1.28e-03230705GO:0005516
GeneOntologyMolecularFunctionsodium-independent organic anion transmembrane transporter activity

SLC22A11 SLCO6A1

1.79e-0318702GO:0015347
GeneOntologyMolecularFunctionsymporter activity

SLC12A4 SLC6A19 SLC6A15 SLC13A3

1.91e-03150704GO:0015293
GeneOntologyBiologicalProcessmonoatomic ion transport

CD84 SFXN4 ADORA2A TCAF1 ADRA1A KCNT2 SLC12A4 MTOR ABCB8 SLC22A11 APLNR SLC6A19 PKD1 SLC6A15 SLC13A3 FCRL5 PLCH1

2.43e-0613747017GO:0006811
GeneOntologyBiologicalProcessG protein-coupled receptor signaling pathway

PRKD3 ADORA2A ADRA1A GPR19 OR6B3 OR1I1 APLNR OR2C3 AIPL1 SYP ADGRV1 OR2F1 GPR162 CHRM5 GRPR ADGRG4 AKAP12

2.99e-0613957017GO:0007186
GeneOntologyBiologicalProcessmonoatomic ion transmembrane transport

SFXN4 TCAF1 ADRA1A KCNT2 SLC12A4 MTOR ABCB8 APLNR SLC6A19 PKD1 SLC6A15 SLC13A3 FCRL5 PLCH1

1.89e-0511157014GO:0034220
GeneOntologyBiologicalProcessmetal ion transport

CD84 ADORA2A ADRA1A KCNT2 SLC12A4 ABCB8 APLNR SLC6A19 PKD1 SLC6A15 SLC13A3 FCRL5 PLCH1

2.74e-0510007013GO:0030001
GeneOntologyBiologicalProcessregulation of protein kinase C signaling

ADRA1A ADGRV1 AKAP12

4.09e-0520703GO:0090036
GeneOntologyBiologicalProcesshomophilic cell adhesion via plasma membrane adhesion molecules

CD84 DCHS2 FAT4 FAT2 PKD1 PCDH15

4.15e-05187706GO:0007156
GeneOntologyBiologicalProcesscondensed mesenchymal cell proliferation

DCHS2 FAT4

6.78e-054702GO:0072137
GeneOntologyBiologicalProcessmonoatomic cation transport

CD84 ADORA2A ADRA1A KCNT2 SLC12A4 ABCB8 APLNR SLC6A19 PKD1 SLC6A15 SLC13A3 FCRL5 PLCH1

1.22e-0411577013GO:0006812
GeneOntologyBiologicalProcessinorganic ion transmembrane transport

ADRA1A KCNT2 SLC12A4 MTOR ABCB8 APLNR SLC6A19 PKD1 SLC6A15 SLC13A3 FCRL5 PLCH1

1.46e-0410177012GO:0098660
GeneOntologyBiologicalProcessdigestion

PGA4 LIPA PGA5 CHRM5 PGA3

2.13e-04160705GO:0007586
GeneOntologyBiologicalProcessinorganic cation transmembrane transport

ADRA1A KCNT2 SLC12A4 ABCB8 APLNR SLC6A19 PKD1 SLC6A15 SLC13A3 FCRL5 PLCH1

2.59e-049227011GO:0098662
GeneOntologyBiologicalProcessanterograde trans-synaptic signaling

ADORA2A GAD2 MYOF ADRA1A SLC12A4 MTOR CNTNAP2 SYP BCHE CHRM5 AKAP12

2.81e-049317011GO:0098916
GeneOntologyBiologicalProcesschemical synaptic transmission

ADORA2A GAD2 MYOF ADRA1A SLC12A4 MTOR CNTNAP2 SYP BCHE CHRM5 AKAP12

2.81e-049317011GO:0007268
GeneOntologyBiologicalProcesstrans-synaptic signaling

ADORA2A GAD2 MYOF ADRA1A SLC12A4 MTOR CNTNAP2 SYP BCHE CHRM5 AKAP12

3.03e-049397011GO:0099537
GeneOntologyBiologicalProcessmonoatomic cation transmembrane transport

ADRA1A KCNT2 SLC12A4 ABCB8 APLNR SLC6A19 PKD1 SLC6A15 SLC13A3 FCRL5 PLCH1

3.11e-049427011GO:0098655
GeneOntologyBiologicalProcessregulation of monoatomic anion transmembrane transport

TCAF1 MTOR

3.14e-048702GO:1903959
GeneOntologyBiologicalProcessstartle response

ADORA2A CNTNAP2 PCDH15

3.64e-0441703GO:0001964
GeneOntologyBiologicalProcessprotein kinase C signaling

ADRA1A ADGRV1 AKAP12

3.64e-0441703GO:0070528
GeneOntologyBiologicalProcesspositive regulation of behavior

ADORA2A MTOR GRPR

4.19e-0443703GO:0048520
GeneOntologyBiologicalProcesssynaptic signaling

ADORA2A GAD2 MYOF ADRA1A SLC12A4 MTOR CNTNAP2 SYP BCHE CHRM5 AKAP12

4.20e-049767011GO:0099536
GeneOntologyBiologicalProcessregulation of synaptic transmission, GABAergic

ADORA2A ADRA1A CNTNAP2

4.80e-0445703GO:0032228
GeneOntologyBiologicalProcessregulation of gap junction assembly

APLNR CNTNAP2

5.02e-0410702GO:1903596
GeneOntologyBiologicalProcessamino acid transport

SFXN4 ADORA2A SLC6A19 SLC6A15 SLC13A3

5.28e-04195705GO:0006865
GeneOntologyCellularComponentmultivesicular body lumen

PGA4 PGA5 PGA3

1.30e-067713GO:0097486
GeneOntologyCellularComponentlate endosome lumen

PGA4 PGA5 PGA3

6.08e-0611713GO:0031906
GeneOntologyCellularComponentendosome lumen

PGA4 PGA5 PGA3

4.20e-0443713GO:0031904
Domain-

FAT4 FAT2 CNTNAP2 WDFY3 ADGRV1 ADGRG4

1.49e-06957062.60.120.200
DomainAspartic_peptidase_N

PGA4 PGA5 PGA3

1.75e-067703IPR012848
DomainA1_Propeptide

PGA4 PGA5 PGA3

1.75e-067703PF07966
DomainAspartic_peptidase_A1

PGA4 PGA5 PGA3

5.94e-0610703IPR001461
DomainPEPTIDASE_A1

PGA4 PGA5 PGA3

5.94e-0610703IPR033121
DomainAsp

PGA4 PGA5 PGA3

5.94e-0610703PF00026
DomainPEPTIDASE_A1

PGA4 PGA5 PGA3

5.94e-0610703PS51767
Domain-

PGA4 PGA5 PGA3

1.08e-05127032.40.70.10
DomainASP_PROTEASE

PGA4 PGA5 PGA3

1.08e-0512703PS00141
DomainAspartic_peptidase_AS

PGA4 PGA5 PGA3

1.40e-0513703IPR001969
DomainPeptidase_aspartic_dom

PGA4 PGA5 PGA3

3.30e-0517703IPR021109
DomainGPCR_Rhodpsn_7TM

ADORA2A ADRA1A GPR19 OR6B3 OR1I1 APLNR OR2C3 OR2F1 GPR162 CHRM5 GRPR

3.68e-056707011IPR017452
Domain7tm_1

ADORA2A ADRA1A GPR19 OR6B3 OR1I1 APLNR OR2C3 OR2F1 GPR162 CHRM5 GRPR

4.04e-056777011PF00001
DomainPDEase_N

PDE1A PDE1C

4.14e-053702IPR013706
DomainPDEase_I_N

PDE1A PDE1C

4.14e-053702PF08499
DomainG_PROTEIN_RECEP_F1_1

ADORA2A ADRA1A GPR19 OR6B3 OR1I1 APLNR OR2C3 OR2F1 GPR162 CHRM5 GRPR

4.49e-056857011PS00237
DomainG_PROTEIN_RECEP_F1_2

ADORA2A ADRA1A GPR19 OR6B3 OR1I1 APLNR OR2C3 OR2F1 GPR162 CHRM5 GRPR

4.86e-056917011PS50262
DomainGPCR_Rhodpsn

ADORA2A ADRA1A GPR19 OR6B3 OR1I1 APLNR OR2C3 OR2F1 GPR162 CHRM5 GRPR

4.93e-056927011IPR000276
DomainNa/ntran_symport_orphan

SLC6A19 SLC6A15

1.37e-045702IPR002438
DomainConA-like_dom

FAT4 FAT2 CNTNAP2 WDFY3 ADGRV1 ADGRG4

1.70e-04219706IPR013320
DomainGPS

PKD1 ADGRV1 ADGRG4

2.78e-0434703SM00303
DomainGPS

PKD1 ADGRV1 ADGRG4

3.03e-0435703PF01825
DomainGPS

PKD1 ADGRV1 ADGRG4

3.29e-0436703PS50221
DomainGPS

PKD1 ADGRV1 ADGRG4

3.58e-0437703IPR000203
DomainLAM_G_DOMAIN

FAT4 FAT2 CNTNAP2

3.87e-0438703PS50025
DomainLaminin_G_2

FAT4 FAT2 CNTNAP2

4.51e-0440703PF02210
DomainLamG

FAT4 FAT2 CNTNAP2

5.98e-0444703SM00282
DomainCadherin_CS

DCHS2 FAT4 FAT2 PCDH15

7.48e-04109704IPR020894
Domain7TM_GPCR_Srsx

ADORA2A ADRA1A GPR19 GRPR

8.29e-04112704SM01381
DomainCADHERIN_1

DCHS2 FAT4 FAT2 PCDH15

8.57e-04113704PS00232
DomainCadherin

DCHS2 FAT4 FAT2 PCDH15

8.57e-04113704PF00028
DomainCADHERIN_2

DCHS2 FAT4 FAT2 PCDH15

8.85e-04114704PS50268
Domain-

DCHS2 FAT4 FAT2 PCDH15

8.85e-041147042.60.40.60
DomainCA

DCHS2 FAT4 FAT2 PCDH15

9.15e-04115704SM00112
DomainCadherin-like

DCHS2 FAT4 FAT2 PCDH15

9.45e-04116704IPR015919
DomainCadherin

DCHS2 FAT4 FAT2 PCDH15

1.01e-03118704IPR002126
DomainLaminin_G

FAT4 FAT2 CNTNAP2

1.34e-0358703IPR001791
DomainSNF

SLC6A19 SLC6A15

2.27e-0319702PF00209
DomainNA_NEUROTRAN_SYMP_1

SLC6A19 SLC6A15

2.27e-0319702PS00610
DomainNA_NEUROTRAN_SYMP_3

SLC6A19 SLC6A15

2.27e-0319702PS50267
DomainPDEase

PDE1A PDE1C

2.27e-0319702IPR023088
DomainNa/ntran_symport

SLC6A19 SLC6A15

2.27e-0319702IPR000175
DomainFA58C

AEBP1 CNTNAP2

2.78e-0321702SM00231
DomainPDEase_I

PDE1A PDE1C

2.78e-0321702PF00233
DomainFA58C_3

AEBP1 CNTNAP2

2.78e-0321702PS50022
DomainPDEASE_I

PDE1A PDE1C

2.78e-0321702PS00126
DomainPDEase_CS

PDE1A PDE1C

2.78e-0321702IPR023174
DomainFA58C_1

AEBP1 CNTNAP2

2.78e-0321702PS01285
DomainFA58C_2

AEBP1 CNTNAP2

2.78e-0321702PS01286
Domain-

PDE1A PDE1C

3.05e-03227021.10.1300.10
DomainPDEase_catalytic_dom

PDE1A PDE1C

3.33e-0323702IPR002073
DomainF5_F8_type_C

AEBP1 CNTNAP2

3.62e-0324702PF00754
DomainHDc

PDE1A PDE1C

3.62e-0324702SM00471
DomainHD/PDEase_dom

PDE1A PDE1C

3.62e-0324702IPR003607
DomainFA58C

AEBP1 CNTNAP2

3.62e-0324702IPR000421
DomainABC_membrane

ABCB8 TAP2

3.62e-0324702PF00664
DomainABC_TM1F

ABCB8 TAP2

4.91e-0328702PS50929
DomainABC1_TM_dom

ABCB8 TAP2

4.91e-0328702IPR011527
PathwayREACTOME_SURFACTANT_METABOLISM

ADORA2A PGA4 PGA5 PGA3

6.53e-0630584M27566
PathwayWP_GPCRS_CLASS_A_RHODOPSINLIKE

ADORA2A ADRA1A GPR19 OR1I1 APLNR OR2F1 CHRM5 GRPR

1.04e-05260588M39397
PathwayWP_GASTRIC_ACID_PRODUCTION

PGA4 PGA5 PGA3

1.07e-0511583M39726
PathwayWP_GPCRS_OTHER

ADORA2A ADGRV1 OR2F1 GPR162 GRPR

3.90e-0593585M39629
PathwayWP_PROXIMAL_TUBULE_TRANSPORT

SLC12A4 SLC22A11 SLC6A19 SLC13A3

8.66e-0557584M39812
PathwayKEGG_CALCIUM_SIGNALING_PATHWAY

ADORA2A PDE1A PDE1C ADRA1A CHRM5 GRPR

8.75e-05178586M2890
PathwayREACTOME_CAM_PDE_1_ACTIVATION

PDE1A PDE1C

2.47e-046582MM14494
PathwayREACTOME_TRANSPORT_OF_BILE_SALTS_AND_ORGANIC_ACIDS_METAL_IONS_AND_AMINE_COMPOUNDS

SLC22A11 SLC6A19 SLC6A15 SLC13A3

3.90e-0484584M27334
PathwayWP_G_PROTEIN_SIGNALING_PATHWAYS

PRKD3 PDE1A PDE1C AKAP12

5.07e-0490584MM15882
PathwayWP_G_PROTEIN_SIGNALING

PRKD3 PDE1A PDE1C AKAP12

5.28e-0491584M39426
PathwayKEGG_TAURINE_AND_HYPOTAURINE_METABOLISM

GAD2 BAAT

7.33e-0410582M12882
PathwayWP_GPCRS_CLASS_A_RHODOPSINLIKE

ADORA2A ADRA1A GPR19 APLNR GRPR

9.86e-04186585MM15994
Pubmed

Close linkage of human chromosomal pepsinogen A genes.

PGA4 PGA5 PGA3

8.15e-0937133017318
Pubmed

Serum pepsinogen test for early detection of gastric cancer in a European country.

PGA4 PGA5 PGA3

8.15e-09371321989121
Pubmed

Serum antibodies to H+,K+-ATPase, serum pepsinogen A and Helicobacter pylori in relation to gastric mucosa morphology in patients with low or low-normal concentrations of serum cobalamins.

PGA4 PGA5 PGA3

8.15e-0937139855083
Pubmed

Advantages of serum pepsinogen A combined with gastrin or pepsinogen C as first-line analytes in the evaluation of suspected cobalamin deficiency: a study in patients previously not subjected to gastrointestinal surgery.

PGA4 PGA5 PGA3

8.15e-0937139797498
Pubmed

The glomerular sieving of pepsinogen A and C in man.

PGA4 PGA5 PGA3

8.15e-0937132478370
Pubmed

Clinical significance of pepsinogen A isozymogens, serum pepsinogen A and C levels, and serum gastrin levels.

PGA4 PGA5 PGA3

8.15e-0937133815274
Pubmed

Pepsinogens: physiology, pharmacology pathophysiology and exercise.

PGA4 PGA5 PGA3

8.15e-09371310675278
Pubmed

The epidemiology of low serum pepsinogen A levels and an international association with gastric cancer rates. EUROGAST Study Group.

PGA4 PGA5 PGA3

8.15e-0937137926498
Pubmed

Pepsinogen A polymorphism in gastric mucosa and urine, with special reference to patients with gastric cancer.

PGA4 PGA5 PGA3

8.15e-0937133780036
Pubmed

Crystal structure of human pepsinogen A.

PGA4 PGA5 PGA3

8.15e-0937139561228
Pubmed

The combination of serum trefoil factor 3 and pepsinogen testing is a valid non-endoscopic biomarker for predicting the presence of gastric cancer: a new marker for gastric cancer risk.

PGA4 PGA5 PGA3

8.15e-09371321455714
Pubmed

Serum pepsinogen level, atrophic gastritis and the risk of incident pancreatic cancer--a prospective cohort study.

PGA4 PGA5 PGA3

8.15e-09371319800305
Pubmed

Identification of a Glu greater than Lys substitution in the activation segment of human pepsinogen A-3 and -5 isozymogens by peptide mapping using endoproteinase Lys-C.

PGA4 PGA5 PGA3

8.15e-0937132901984
Pubmed

Assignment of human pepsinogen A locus to the q12-pter region of chromosome 11.

PGA4 PGA5 PGA3

8.15e-0937133839486
Pubmed

Serum pepsinogen reference intervals in apparently healthy Chinese population with latex enhanced turbidimetric immunoassay.

PGA4 PGA5 PGA3

8.15e-09371324170207
Pubmed

Assignment of the pepsinogen gene complex (PGA) to human chromosome region 11q13 by in situ hybridization.

PGA4 PGA5 PGA3

8.15e-0937133467902
Pubmed

The pepsinogens of human gastric mucosa.

PGA4 PGA5 PGA3

8.15e-0937134586732
Pubmed

Relationships between the human pepsinogen DNA and protein polymorphisms.

PGA4 PGA5 PGA3

8.15e-0937133014868
Pubmed

Genomic structure and evolution of the human pepsinogen A multigene family.

PGA4 PGA5 PGA3

8.15e-0937132892778
Pubmed

The value of serum pepsinogen levels for the diagnosis of gastric diseases in Chinese Han people in midsouth China.

PGA4 PGA5 PGA3

8.15e-09371324383519
Pubmed

Gene structures of pepsinogens A and C.

PGA4 PGA5 PGA3

8.15e-0937131455184
Pubmed

Hypomethylation and expression of pepsinogen A genes in the fundic mucosa of human stomach.

PGA4 PGA5 PGA3

8.15e-0937132831884
Pubmed

The ratio of pepsinogen A to pepsinogen C: a sensitive test for atrophic gastritis.

PGA4 PGA5 PGA3

8.15e-0937132799289
Pubmed

CRYSTALLINE PEPSIN : I. ISOLATION AND TESTS OF PURITY.

PGA4 PGA5 PGA3

8.15e-09371319872561
Pubmed

Human pepsinogen A (PGA): an informative gene complex located at 11q13.

PGA4 PGA5 PGA3

8.15e-0937131968039
Pubmed

Localization of pepsinogen (A and C) and cellular differentiation of pepsinogen-synthesizing cells in the human gastric mucosa.

PGA4 PGA5 PGA3

8.15e-0937132032552
Pubmed

Helicobacter pylori infection and serum pepsinogen A, pepsinogen C, and gastrin in gastritis and peptic ulcer: significance of inflammation and effect of bacterial eradication.

PGA4 PGA5 PGA3

8.15e-0937138053437
Pubmed

Analysis of the promoter of a human pepsinogen A gene.

PGA4 PGA5 PGA3

8.15e-0937131812762
Pubmed

O6-methylguanine in blood leucocyte DNA: an association with the geographic prevalence of gastric cancer and with low levels of serum pepsinogen A, a marker of severe chronic atrophic gastritis. The EUROGAST Study Group.

PGA4 PGA5 PGA3

8.15e-0937137923573
Pubmed

Family and population studies on the human pepsinogen A multigene family.

PGA4 PGA5 PGA3

8.15e-0937132566575
Pubmed

Fast detection of phosphorylation of human pepsinogen A, human pepsinogen C and swine pepsinogen using a combination of reversed-phase high-performance liquid chromatography and capillary zone electrophoresis for peptide mapping.

PGA4 PGA5 PGA3

8.15e-0937139061458
Pubmed

Ratio between serum IL-8 and pepsinogen A/C: a marker for atrophic body gastritis.

PGA4 PGA5 PGA3

8.15e-09371312588289
Pubmed

Immunoblot technique to visualise serum pepsinogen A isozymogen patterns.

PGA4 PGA5 PGA3

8.15e-0937132229438
Pubmed

Prediction of gastric cancer development by serum pepsinogen test and Helicobacter pylori seropositivity in Eastern Asians: a systematic review and meta-analysis.

PGA4 PGA5 PGA3

8.15e-09371325314140
Pubmed

Validation of the pepsinogen test method for gastric cancer screening using a follow-up study.

PGA4 PGA5 PGA3

8.15e-09371319890696
Pubmed

Gastric cancer detection using gastric juice pepsinogen and melanoma-associated gene RNA.

PGA4 PGA5 PGA3

8.15e-09371323897256
Pubmed

An aspartic proteinase expressed in the yolk sac and neonatal stomach of the mouse.

PGA4 PGA5 PGA3

8.15e-09371311566730
Pubmed

The effect of acute and chronic protein loading on urinary pepsinogen A excretion.

PGA4 PGA5 PGA3

8.15e-0937131956484
Pubmed

Transcription regulation of human and porcine pepsinogen A.

PGA4 PGA5 PGA3

8.15e-0937138540382
Pubmed

Diagnostic value of serum pepsinogen C in patients with raised serum concentrations of pepsinogen A.

PGA4 PGA5 PGA3

8.15e-0937138244094
Pubmed

Plasma pepsinogens, antibodies against Helicobacter pylori, and risk of gastric cancer in the Shanghai Women's Health Study Cohort.

PGA4 PGA5 PGA3

8.15e-09371321407214
Pubmed

Exploratory findings of audiometry in adult patients with otitis media with high pepsinogen concentrations: a preliminary study.

PGA4 PGA5 PGA3

8.15e-09371322992016
Pubmed

The role of serum pepsinogen in the detection of gastric cancer.

PGA4 PGA5 PGA3

8.15e-09371320981206
Pubmed

Isolation of an activation intermediate and determination of the amino acid sequence of the activation segment of human pepsinogen A.

PGA4 PGA5 PGA3

8.15e-0937136774973
Pubmed

Gastric chief cell-specific transcription of the pepsinogen A gene.

PGA4 PGA5 PGA3

8.15e-0937138504820
Pubmed

Detection of pepsinogen in the neonatal lung and stomach by immunohistochemistry.

PGA4 PGA5 PGA3

8.15e-09371321970995
Pubmed

Primary structure of human pepsinogen gene.

PGA4 PGA5 PGA3

8.15e-0937136300126
Pubmed

Pepsinogen I/II ratio is related to glucose, triacylglycerol, and uric acid levels.

PGA4 PGA5 PGA3

8.15e-09371322304859
Pubmed

Pepsinogen I and II expressions in situ and their correlations with serum pesignogen levels in gastric cancer and its precancerous disease.

PGA4 PGA5 PGA3

8.15e-09371324004680
Pubmed

Effect of enprostil on serum gastrin and pepsinogen A and C levels in patients on long-term treatment with omeprazole.

PGA4 PGA5 PGA3

8.15e-0937138038355
Pubmed

Serum pepsinogens in gastric cancer screening.

PGA4 PGA5 PGA3

8.15e-09371320428942
Pubmed

Human pepsinogen A isozymogen patterns in serum and gastric mucosa.

PGA4 PGA5 PGA3

8.15e-0937132227273
Pubmed

The relationship of Helicobacter pylori colonization, the serum pepsinogen A level, and gastric resection.

PGA4 PGA5 PGA3

8.15e-0937139525001
Pubmed

Evaluation of pepsinogen A and gastrin-17 as markers of gastric cancer and high-risk pathologic conditions.

PGA4 PGA5 PGA3

8.15e-0937137886402
Pubmed

Identification of a high risk gastric cancer group using serum pepsinogen after successful eradication of Helicobacter pylori.

PGA4 PGA5 PGA3

8.15e-09371323034090
Pubmed

A possible association of low pepsinogen I and pepsinogen I/II with low and high body weight in Japanese men.

PGA4 PGA5 PGA3

8.15e-09371324125879
Pubmed

Serum pepsinogen and gastric cancer screening.

PGA4 PGA5 PGA3

8.15e-09371317379991
Pubmed

Effects of omeprazole and lansoprazole on fasting and postprandial serum gastrin and serum pepsinogen A and C.

PGA4 PGA5 PGA3

8.15e-0937138751234
Pubmed

Enzyme-linked immunosorbent assay and radioimmunoassay of serum pepsinogen A.

PGA4 PGA5 PGA3

8.15e-0937133554488
Pubmed

Low serum pepsinogen I and pepsinogen I/II ratio and Helicobacter pylori infection are associated with increased risk of gastric cancer: 14-year follow up result in a rural Chinese community.

PGA4 PGA5 PGA3

8.15e-09371321547904
Pubmed

Expression of serum miR-20a-5p, let-7a, and miR-320a and their correlations with pepsinogen in atrophic gastritis and gastric cancer: a case-control study.

PGA4 PGA5 PGA3

8.15e-09371323521833
Pubmed

Serum pepsinogen I/II ratio is correlated with albuminuria in patients with type 2 diabetes.

PGA4 PGA5 PGA3

3.26e-08471323047493
Pubmed

Pepsinogens, progastricsins, and prochymosins: structure, function, evolution, and development.

PGA4 PGA5 PGA3

3.26e-08471311915945
Pubmed

Pepsinogen A and C serum levels in relation to acute NSAID-associated mucosal lesions in healthy volunteers.

PGA4 PGA5 PGA3

3.26e-0847138322031
Pubmed

Transcription factor SOX2 up-regulates stomach-specific pepsinogen A gene expression.

PGA4 PGA5 PGA3

3.26e-08471317136346
Pubmed

Pepsinogen A, pepsinogen C, and gastrin as markers of atrophic chronic gastritis in European dyspeptics.

PGA4 PGA5 PGA3

3.26e-08471312698190
Pubmed

Accuracy and cut-off values of pepsinogens I, II and gastrin 17 for diagnosis of gastric fundic atrophy: influence of gastritis.

PGA4 PGA5 PGA3

8.13e-08571322066020
Pubmed

Expression of mouse dchs1, fjx1, and fat-j suggests conservation of the planar cell polarity pathway identified in Drosophila.

DCHS2 FAT4 FAT2

2.84e-07771316059920
Pubmed

Crystal structure of human pepsin and its complex with pepstatin.

PGA4 PGA5

4.11e-0627127663352
Pubmed

Regulation of mTOR by polycystin-1: is polycystic kidney disease a case of futile repair?

MTOR PKD1

4.11e-06271217102641
Pubmed

Slow-wave sleep is controlled by a subset of nucleus accumbens core neurons in mice.

ADORA2A GAD2

4.11e-06271228963505
Pubmed

Nucleotide sequence comparison of five human pepsinogen A (PGA) genes: evolution of the PGA multigene family.

PGA4 PGA5

4.11e-0627122714789
Pubmed

Activation of human pepsinogens.

PGA4 PGA5

4.11e-0627123197840
Pubmed

Activation of mTOR pathway in myeloid-derived suppressor cells stimulates cancer cell proliferation and metastasis in lal(-/-) mice.

LIPA MTOR

4.11e-06271224882582
Pubmed

Identification of new human cadherin genes using a combination of protein motif search and gene finding methods.

DCHS2 FAT4

4.11e-06271215003449
Pubmed

Isolation of human, swine, and rat prepepsinogens and calf preprochymosin, and determination of the primary structures of their NH2-terminal signal sequences.

PGA4 PGA5

4.11e-0627122415509
Pubmed

Stage and cell-specific expression of calmodulin-dependent phosphodiesterases in mouse testis.

PDE1A PDE1C

4.11e-06271211369604
Pubmed

Cooperative action of APJ and α1A-adrenergic receptor in vascular smooth muscle cells induces vasoconstriction.

ADRA1A APLNR

4.11e-06271231504625
Pubmed

Glypican-6 and Glypican-4 stimulate embryonic stomach growth by regulating Hedgehog and noncanonical Wnt signaling.

PGA4 PGA5 PGA3

6.51e-061871336057966
Pubmed

Requirement of FAT and DCHS protocadherins during hypothalamic-pituitary development.

DCHS2 FAT4 FAT2

6.51e-061871333108146
Pubmed

Slitrk4 is required for the development of inhibitory neurons in the fear memory circuit of the lateral amygdala.

GAD2 SYP GRPR

1.22e-052271338736483
Pubmed

Polycystin-1 affects cancer cell behaviour and interacts with mTOR and Jak signalling pathways in cancer cell lines.

MTOR PKD1

1.23e-05371231251475
Pubmed

Hyperactive Akt-mTOR pathway as a therapeutic target for pain hypersensitivity in Cntnap2-deficient mice.

MTOR CNTNAP2

1.23e-05371231874168
Pubmed

mTOR and differential activation of mitochondria orchestrate neutrophil chemotaxis.

ADORA2A MTOR

1.23e-05371226416965
Pubmed

Receptor-mediated stimulation of lipid signalling pathways in CHO cells elicits the rapid transient induction of the PDE1B isoform of Ca2+/calmodulin-stimulated cAMP phosphodiesterase.

PDE1A PDE1C

1.23e-0537129003415
Pubmed

A comparative study on the NH2-terminal amino acid sequences and some other properties of six isozymic forms of human pepsinogens and pepsins.

PGA4 PGA5

1.23e-0537122515193
Pubmed

Kinetic properties of Ca2+/calmodulin-dependent phosphodiesterase isoforms dictate intracellular cAMP dynamics in response to elevation of cytosolic Ca2+.

PDE1A PDE1C

1.23e-05371218335582
Pubmed

Molecular cloning and characterization of a calmodulin-dependent phosphodiesterase enriched in olfactory sensory neurons.

PDE1A PDE1C

1.23e-0537127568196
Pubmed

mTORC1-mediated inhibition of polycystin-1 expression drives renal cyst formation in tuberous sclerosis complex.

MTOR PKD1

1.23e-05371226931735
Pubmed

Regulated vesicular trafficking of specific PCDH15 and VLGR1 variants in auditory hair cells.

PCDH15 ADGRV1

1.23e-05371223035094
Pubmed

Cyclic nucleotide phosphodiesterase PDE1C1 in human cardiac myocytes.

PDE1A PDE1C

1.23e-05371217726023
Pubmed

The physiological roles of vesicular GABA transporter during embryonic development: a study using knockout mice.

GAD2 SYP

2.46e-05471221190592
Pubmed

Interaction of protocadherin-15 with the scaffold protein whirlin supports its anchoring of hair-bundle lateral links in cochlear hair cells.

PCDH15 ADGRV1

2.46e-05471233009420
Pubmed

Usher syndromes due to MYO7A, PCDH15, USH2A or GPR98 mutations share retinal disease mechanism.

PCDH15 ADGRV1

2.46e-05471218463160
Pubmed

Polycystin-1 regulates extracellular signal-regulated kinase-dependent phosphorylation of tuberin to control cell size through mTOR and its downstream effectors S6K and 4EBP1.

MTOR PKD1

2.46e-05471219255143
Pubmed

Role for a novel Usher protein complex in hair cell synaptic maturation.

PCDH15 ADGRV1

2.46e-05471222363448
Pubmed

The inherited blindness protein AIPL1 regulates the ubiquitin-like FAT10 pathway.

AIPL1 UBA6

4.09e-05571222347407
Pubmed

Scaffold protein harmonin (USH1C) provides molecular links between Usher syndrome type 1 and type 2.

PCDH15 ADGRV1

4.09e-05571216301216
Pubmed

Multiple roles of epithelial heparan sulfate in stomach morphogenesis.

PGA4 PGA5 PGA3

5.09e-053571329700203
Pubmed

Reviews in molecular biology and biotechnology: transmembrane signaling by G protein-coupled receptors.

ADORA2A ADRA1A APLNR CHRM5 GRPR

5.72e-0520071518240029
Cytoband7q35

TCAF1 CNTNAP2 OR2F1

8.78e-05557137q35
CytobandEnsembl 112 genes in cytogenetic band chr7q35

TCAF1 CNTNAP2 OR2F1

1.51e-0466713chr7q35
GeneFamilyCadherin related

DCHS2 FAT4 FAT2 PCDH15

1.64e-071754424
GeneFamilyATP binding cassette subfamily B

ABCB8 TAP2

4.73e-0411542806
GeneFamilySolute carriers

SLC12A4 SLC22A11 SLC6A19 SLC6A15 SLC13A3 SLCO6A1

1.12e-03395546752
GeneFamilyPhosphodiesterases

PDE1A PDE1C

2.32e-0324542681
CoexpressionGSE13411_IGM_VS_SWITCHED_MEMORY_BCELL_UP

CD84 MYOF AEBP1 SYP WDFY3 PLCH1

1.42e-05193716M3247
CoexpressionGSE360_CTRL_VS_L_MAJOR_MAC_DN

MYOF PDE1A PDE1C SLC12A4 SLC13A3 GRPR

1.59e-05197716M5161
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 PDE1C DNAH10 PCDH15 MUC5B ADGRV1 PLCH1 PKHD1L1

5.73e-101847182cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 PDE1C DNAH10 PCDH15 MUC5B ADGRV1 PLCH1 PKHD1L1

5.73e-10184718ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 PDE1C DNAH10 PCDH15 MUC5B ADGRV1 PLCH1 PKHD1L1

5.73e-101847182b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellfacs-Diaphragm-Limb_Muscle-24m|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAH10 AEBP1 CNTNAP2 PCDH15 ADGRV1 PLCH1 PKHD1L1

1.01e-0816971712bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MYOF DCHS2 PDE1A KCNT2 AEBP1 PGA5 AKAP12

3.12e-08199717b9338b739162cd8e5661c9a4dcb41a31219b5723
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MYOF DCHS2 PDE1A KCNT2 AEBP1 PGA5 AKAP12

3.12e-08199717c972d3036151403f26fa9d6271520639c281ab84
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Lect1_Oxtr|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GAD2 KCNT2 AEBP1 CNTNAP2 PCDH15 GRPR

1.43e-0714971610ffd0051fb027bbebc662ca602c80d89bbf99c6
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNT2 DNAH10 CNTNAP2 MUC5B ADGRV1 PKHD1L1

2.18e-07160716c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNT2 DNAH10 CNTNAP2 MUC5B ADGRV1 PKHD1L1

2.18e-0716071625c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Ptprt_Pkp2|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GAD2 AEBP1 CNTNAP2 PCDH15 BCHE GRPR

3.82e-0717671605ec715439f2eb1696f5d8855da0dd1dd70effd0
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GAD2 FAT4 PDE1C ADRA1A KCNT2 FRMPD3

4.65e-071827167dc61e901428cea04f00ebb0939a44d21a6145c6
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GAD2 ADRA1A KCNT2 PCDH15 FRMPD3 GRPR

5.79e-07189716f0aaf2994d319a39877d2845eaab9f166adead4e
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Igfbp6_Pltp|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PRKD3 GAD2 FAT4 ADRA1A FRMPD3

2.89e-061397159e9f29f92dbe65b26cc78b3a1c00778c6a701f5b
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

FAT4 SYT14 PCDH15 OR2C3 MUC5B

4.07e-06149715c5eedb54ef2e0f131aa6730612c921bc19479632
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_granulocytic|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

FAT4 SYT14 PCDH15 OR2C3 MUC5B

4.07e-06149715a22417286de8606f0cc94f86b70bce17aeefb9c2
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Lect1_Oxtr|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GAD2 KCNT2 AEBP1 CNTNAP2 GRPR

4.93e-0615571599e749f7075e2c64e9a0bf91009f95b6969197c8
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Rspo4_Rxfp1_Chat|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

FAT4 KCNT2 AEBP1 CNTNAP2 GRPR

4.93e-061557153b8def9e8f66511736ea37f259511f7c8b7743af
ToppCellfacs-Lung-nan-3m-Endothelial-Capillary_Type_1_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAH10 BAAT SLC6A19 ATP10B PLCH1

5.75e-06160715f2cdee5a9e3b0eb125d6be7b5d239eb04333ae41
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DNAH10 BAAT PCDH15 ADGRV1 PKHD1L1

6.11e-06162715bf886e22ff2a20353499004b53f25fb9e6574896
ToppCellPosterior_cortex-Neuronal-Inhibitory|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

GAD2 ADRA1A CNTNAP2 FRMPD3 GRPR

7.09e-061677159a84f45345c75f2c8ff38a04245aadee2a26a240
ToppCellfacs-Diaphragm-Limb_Muscle-24m-Mesenchymal|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAH10 AEBP1 PCDH15 PLCH1 PKHD1L1

8.41e-0617371566f37c1437705734b20601656fa4aa1d92ca30be
ToppCellfacs-Diaphragm-Limb_Muscle-24m-Mesenchymal-nan|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAH10 AEBP1 PCDH15 PLCH1 PKHD1L1

8.41e-06173715649b08a409095592cccf31883be69c754411280d
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6-Inh_L1_PAX6_GRIP2|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GAD2 DCHS2 ADRA1A BCHE GRPR

8.89e-061757150c648e7f67ffbe3b476a2ca77d246554f8cd1882
ToppCellEndothelial-B-SSc-ILD_02|World / lung cells shred on cell class, cell subclass, sample id

PDE1A AEBP1 BCHE PKHD1L1 AKAP12

9.14e-06176715b288116a4588a1f9db9d49af92cea118937c9201
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-mesothelial_cell-Mesothelium|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CTAGE1 PCDH15 AIPL1 BCHE PKHD1L1

1.10e-051837159d5a363fbe6f0a1668c9d584df65ee1c283349c7
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-mesothelial_cell|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CTAGE1 PCDH15 AIPL1 BCHE PKHD1L1

1.10e-05183715c5caac6ed6c8d67f5c336281d9fd903976509445
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_2|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GAD2 FAT4 ADRA1A KCNT2 FRMPD3

1.16e-05185715cefd81adb480c027545a5c78dcd05669783717f4
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GAD2 FAT4 ADRA1A KCNT2 FRMPD3

1.23e-05187715ae2ee6f8e5c37cb88a67f3e742cf86e57657bfaf
ToppCellRA-10._Endothelium_II|World / Chamber and Cluster_Paper

PDE1A KCNT2 PCDH15 PKHD1L1 AKAP12

1.29e-0518971575c248b9de5e2fb7a0baa8cdbab516e575cc4394
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GAD2 FAT4 ADRA1A KCNT2 SERINC1

1.36e-05191715764c3a8829ae1253a0790744138266e81fc075ec
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GAD2 ADRA1A PCDH15 FRMPD3 GRPR

1.36e-051917157b386512284dfaa0e95358b28ee82632ee965e64
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GAD2 FAT4 ADRA1A KCNT2 FRMPD3

1.39e-051927153abee376c37c3646da33ac381aa63d50a01607a6
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GAD2 PDE1C CNTNAP2 PCDH15 PLCH1

1.43e-05193715658c2b30a4d806c5ce78ea4392fe8eb86b8d1e99
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MYOF KCNT2 AEBP1 PGA5 AKAP12

1.54e-0519671534e79918a448f6c19b87e1b1ce13c012b24be1f8
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MYOF KCNT2 AEBP1 PGA5 AKAP12

1.54e-051967158f82e01ca50aa4cd6149547505b4474a02fad618
ToppCellBronchial-NucSeq-Stromal-Myofibroblastic-Muscle_perivascular_immune_recruiting|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TBX15 PDE1A PDE1C KCNT2 AKAP12

1.58e-05197715cfb3dc4b401800e33c82cfc3baee69dbbd16ac8c
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW10-Neuronal|GW10 / Sample Type, Dataset, Time_group, and Cell type.

PDE1A TCAF1 SERINC1 CNTNAP2 SLC6A15

1.65e-05199715b2508bf591720830e8e3494b1337aab14539956d
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-ADGRG6-|Neuronal / cells hierarchy compared to all cells using T-Statistic

GAD2 PDE1C CNTNAP2 PCDH15 PLCH1

1.69e-05200715a9cdddc4e985dae59521e557479c24fcc2ac727d
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-STK32A-|Neuronal / cells hierarchy compared to all cells using T-Statistic

GAD2 PDE1C CNTNAP2 PCDH15 PLCH1

1.69e-052007156a44439e4a7ce3627271375b04cfcfb9467218f4
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-ADGRG6--L3-5|Neuronal / cells hierarchy compared to all cells using T-Statistic

GAD2 PDE1C CNTNAP2 PCDH15 PLCH1

1.69e-0520071533b9199e0dfc267e2cea20b82d1c167f8adcc635
ToppCellNeuronal-Inhibitory-iA-iA_1(SST_PAX6)|Neuronal / cells hierarchy compared to all cells using T-Statistic

GAD2 FAT4 ADRA1A CNTNAP2 FRMPD3

1.69e-05200715d0167f96314be78b6d867bbcc6e4396071d931b8
ToppCellNeuronal-Inhibitory-iA|Neuronal / cells hierarchy compared to all cells using T-Statistic

GAD2 FAT4 ADRA1A FRMPD3 GRPR

1.69e-052007155ef4a3dc18a44292184a59ced916183c0699b01e
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-STK32A|Neuronal / cells hierarchy compared to all cells using T-Statistic

GAD2 PDE1C CNTNAP2 PCDH15 PLCH1

1.69e-052007158d51b4f7b7002ee51401ebe5eaca1e8f04bfadd5
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FAT4 KCNT2 AEBP1 ADGRG4 AKAP12

1.69e-052007153dd022e974fec7013ba18f333da63f58fbf2dd7c
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-ADGRG6|Neuronal / cells hierarchy compared to all cells using T-Statistic

GAD2 PDE1C CNTNAP2 PCDH15 PLCH1

1.69e-052007159719fabddc34051949468a7520289e3c750de4f8
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-STK32A--L4-5|Neuronal / cells hierarchy compared to all cells using T-Statistic

GAD2 PDE1C CNTNAP2 PCDH15 PLCH1

1.69e-05200715cb1f4b0d66da5b0466ff17b29e7034d451d93e4f
ToppCellTracheal-10x5prime-Immune_Myeloid-Macrophage_other-Macrophage_intravascular|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CD84 PGA4 TPP1 PGA5 PGA3

1.69e-05200715a1ae299cf77580a6d1a728ee591888b6d70a19d6
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Igfbp6_Pltp|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PRKD3 GAD2 FAT4 FRMPD3

4.63e-0512471436dfc702a570e1a1a6dde09f38badf9023ea7287
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Rspo1_Itga4|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

FAT4 PDE1C KCNT2 GRPR

8.28e-051447147de962346ba9653d90dd13bb7d977fe44d200bba
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Ntn1_Npy2r|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PRKD3 GAD2 ADRA1A CNTNAP2

9.20e-051487145e738522d4ad35e08bc4ff8c41b7bea38ec6ef95
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-high_Fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DCHS2 GPR19 KCNT2 SLC12A4

9.69e-051507141270f33f9d7e46e55adf1a96e8beee858b95589d
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-high_Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DCHS2 GPR19 KCNT2 SLC12A4

9.69e-05150714156118ce1d69522624196410cba18b8354cd0bb4
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Ntn1_Npy2r|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GAD2 FAT4 ADRA1A CNTNAP2

1.02e-041527148ff5a178a8f3550d89a003c0858820aab3773386
ToppCellThalamus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Gata3_(Periacqueductal_gray_(PAG)_(or_adjacent_APTD))--|Thalamus / BrainAtlas - Mouse McCarroll V32

AIPL1 PKHD1L1 GRPR

1.04e-04577139614fe2acc6ee039383504f94bbe6d35aac27f25
ToppCellThalamus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Gata3_(Periacqueductal_gray_(PAG)_(or_adjacent_APTD))|Thalamus / BrainAtlas - Mouse McCarroll V32

AIPL1 PKHD1L1 GRPR

1.04e-0457713309b3d48bfe215d7b581722c06d444b5b2ef6a30
ToppCellThalamus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Gata3_(Periacqueductal_gray_(PAG)_(or_adjacent_APTD))-|Thalamus / BrainAtlas - Mouse McCarroll V32

AIPL1 PKHD1L1 GRPR

1.04e-04577133c55a5598a7ea789500f2fbd35c79d2b97a3fc7d
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Arhgap36_Hmcn1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GAD2 ADRA1A SLC12A4 GRPR

1.05e-041537149c6fce56300ba5053efda59a438d63a808c497c0
ToppCellPosterior_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

GAD2 ADRA1A FRMPD3 GRPR

1.10e-04155714105d59d8a1bb8cb37eef2c1767d737b2108ac7c5
ToppCell368C-Fibroblasts-Fibroblast-E|368C / Donor, Lineage, Cell class and subclass (all cells)

TBX15 GPR19 SLC13A3 PLCH1

1.30e-04162714e17632778a57c71d6005d3abca3a0443a92040e7
ToppCell368C-Fibroblasts-Fibroblast-E-|368C / Donor, Lineage, Cell class and subclass (all cells)

TBX15 GPR19 SLC13A3 PLCH1

1.30e-04162714ac4a80fd72c9311ea2b3e574c6284bbce4f2756c
ToppCell343B-Fibroblasts-Fibroblast-D-|343B / Donor, Lineage, Cell class and subclass (all cells)

PDE1A ABCB8 APLNR AKAP12

1.34e-041637148d2b2119c6b3d5b677da6f377fd85146590e1246
ToppCell343B-Fibroblasts-Fibroblast-D|343B / Donor, Lineage, Cell class and subclass (all cells)

PDE1A ABCB8 APLNR AKAP12

1.34e-04163714acfb2ece6202479e615d54fd3ecb8b4a571b5a18
ToppCell5'-GW_trimst-2-LargeIntestine-Epithelial-epithelial_progenitor_cell-Distal_progenitor|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ATP10B SLC13A3 ADGRV1 PLCH1

1.37e-04164714d6f71d804bb65301c02ea4e6673e20688b5fcd5b
ToppCellfacs-Trachea-3m-Hematologic-myeloid-granulocyte-granulocyte_l26|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CD84 ADORA2A PDE1C INPP5B

1.40e-0416571423955e3373660f827518e723ac62fba99753f375
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-CD4-positive,_alpha-beta_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SFXN4 PDE1A SLC12A4 CHRM5

1.47e-04167714713899690e4acd9d259645e363c26983d6ef3022
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-BM_CD4_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SFXN4 PDE1A SLC12A4 CHRM5

1.47e-04167714d30b96c39da3dd02500443877a4eb3500e26802c
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L6_LHX6_GLP1R|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GAD2 FAT4 BCHE PLCH1

1.50e-041687142eed7dc1a2aff11be024823c4323c42bc94362f6
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC22A11 SLC6A19 PCDH15 SLC13A3

1.50e-04168714fa0d251693935116adf633d02b7ec4a295100865
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYOF FAT4 PDE1C KCNT2

1.53e-04169714c0824a93674e2bff0f09b2d2fab5bab016a2e379
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Vip|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GAD2 PDE1C KCNT2 GRPR

1.60e-041717145efd15300f865ebf651e0888265cbd717bc3b9d3
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L4-5_RORB_LCN15|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PDE1A PDE1C LIPA KCNT2

1.60e-041717149e00c8191ca9d52151a49baf39f8581cb176fb76
ToppCellCOVID-19-kidney-PEC|kidney / Disease (COVID-19 only), tissue and cell type

PDE1A KCNT2 AEBP1 AKAP12

1.64e-0417271436a96714a0eb6ac438648135336c9791881ddadb
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GAD2 AEBP1 CNTNAP2 GRPR

1.64e-041727147e1a7700a4c2b1d100da1d6e475e73498ebb605a
ToppCell10x5'-Lung-Lymphocytic_B-Memory_B_cells|Lung / Manually curated celltypes from each tissue

ADRA1A AEBP1 FCRL5 PKHD1L1

1.64e-041727142cb2dc7cfd6db5a98a393b1a84c23abf3d692a53
ToppCell356C-Fibroblasts-Fibroblast-B_(Myofibroblast)|356C / Donor, Lineage, Cell class and subclass (all cells)

TBX15 PDE1A AEBP1 BCHE

1.68e-0417371475e26a65071b0d2f30ed0b2aa9859c488f5cf362
ToppCell356C-Fibroblasts-Fibroblast-B_(Myofibroblast)-|356C / Donor, Lineage, Cell class and subclass (all cells)

TBX15 PDE1A AEBP1 BCHE

1.68e-0417371426e2e674f5d312fa8f61c11b553dc6101f063b16
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Chat_Htr1f|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GAD2 PDE1C AEBP1 GRPR

1.72e-04174714a5f2a4e3b25e6084bd7003a53da86a44f6fcf294
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MYOF DCHS2 FAT4 ADRA1A

1.72e-041747147d4b860e05b5931f6f9d757a68f75ff35597a47a
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FAT4 KCNT2 AEBP1 BCHE

1.75e-041757141799a7be623dc3bf53ba580a7c47d2619969d708
ToppCellPND03-Epithelial-Epithelial_Airway-Neurosecretory-PNEC-PNEC_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PDE1C SYT14 SYP GPR162

1.75e-041757148362a46f5804333baa84cd56d450bc147f372a7e
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PDE1A PDE1C LIPA KCNT2

1.75e-0417571406af6629766e2054e6995e8cdb3907658fec49d3
ToppCellPND03-Epithelial-Epithelial_Airway-Neurosecretory-PNEC|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PDE1C SYT14 SYP GPR162

1.75e-041757148b4c62e608f0ec84e563bbf0ebffe3ed44085298
ToppCellfacs-Marrow-B-cells-24m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNT2 CNTNAP2 FCRL5 ADGRV1

1.75e-04175714887e75fc90e59a6394d62f3c048a9cfdf6707725
ToppCellNS-moderate-d_07-13-Lymphoid-NK|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

FAT4 AEBP1 SLC6A15 AKAP12

1.75e-04175714f6cd24d22f62469319f9d244e3e5de527d3d4d94
ToppCell3'-Child09-12-SmallIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DCHS2 KCNT2 AEBP1 BCHE

1.79e-04176714a8875b4ba4abf6625cdeb67bf544ce1573c59060
ToppCellPND07-28-samps-Mesenchymal-Myofibroblast-myofibroblast_-_mature_-_DCN|PND07-28-samps / Age Group, Lineage, Cell class and subclass

KCNT2 SLC12A4 AEBP1 AKAP12

1.79e-0417671408f94b78b27feeb113dbfadbfa7fe34d08b2809b
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L6_LHX6_GLP1R|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GAD2 FAT4 BCHE PLCH1

1.83e-041777142b675840b7d2bb536c2c600936733bd9e97e7120
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L6_LHX6_GLP1R|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GAD2 FAT4 BCHE PLCH1

1.83e-041777145e0fca9bd5e5ffe6d39f5bcd81f36512f3b0cb1b
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_ADARB2_ADAM33|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GAD2 FAT4 ADRA1A PLCH1

1.83e-041777141cb78133ac09ea3a3f5b5de07151033998406512
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2-Exc_L6_FEZF2_SLITRK6|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DCHS2 FAT4 PCDH15 CHRM5

1.83e-0417771462f180d5a487b449f715de49ee1e1e11c4e0cf4d
ToppCell3'-GW_trimst-1.5-SmallIntestine-Epithelial-neuro-epithelial-K_cells_(GIP+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GAD2 SLC6A19 PKHD1L1 ADGRG4

1.83e-0417771443dce527392f3b8364bb6a55268ce9d6518d3a29
ToppCell5'-Adult-LymphNode-Endothelial-lymphatic_endothelial-LEC5_(CLDN11+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PDE1A PCDH15 PKHD1L1 AKAP12

1.87e-041787144b3ea0921bc598ebb9f63780ecdf8ad4349f3666
ToppCellAdult-Endothelial-endothelial_cell_of_lymph_vessel-D231|Adult / Lineage, Cell type, age group and donor

DCHS2 PDE1A PKHD1L1 AKAP12

1.87e-04178714c80ca7a2d3f976089a5e71d0cd9ba9a1c0bd2815
ToppCellPCW_05-06-Neuronal-Neuronal_postreplicative-neuro_migrating_neuronal_(3)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

PDE1C SYT14 SYP ADGRV1

1.87e-0417871438ffbd01230c99f52274424ee6c172381daffc73
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

UBA6 ATP10B MUC5B ADGRV1

1.91e-041797146e965e424eebef50f0202cff75f458be395cfca1
ToppCellCOVID-19-kidney-Epi_(Mes)|kidney / Disease (COVID-19 only), tissue and cell type

DCHS2 PDE1A KCNT2 AEBP1

1.91e-04179714e7c9dc63f03d3f3746b51a7e3c8393089e2ceb7d
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_SST_CXCL14|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GAD2 FAT4 PDE1C ADRA1A

1.91e-04179714c7afbd10072d36a35cd20ae73670d76b9cefd22d
ToppCell3'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC5_(CLDN11+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PDE1A BCHE PKHD1L1 AKAP12

1.91e-04179714ec1d7017da325647b629de703135a404bbdc627d
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ADRA1A BCHE FRMPD3 GRPR

1.91e-041797140b6731d9554f8bed1899c165a50e6b329ea19a6d
ToppCell3'-GW_trimst-2-SmallIntestine-Neuronal-neurons_B-Branch_B2_(eMN)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GPR19 PCDH15 AIPL1 SYP

1.95e-041807147d3d5608647b6e684e8e185993d106a38c53e76a
DrugN-methyl-DL-aspartic acid

PRKD3 ADORA2A GAD2 ADRA1A MTOR ABCB8 BAAT PKD1 SYP BCHE ADGRV1 TAP2

7.89e-076557112CID000004376
Drugfluridone

PRKD3 PDE1A PDE1C MTOR PKD1

5.79e-0682715CID000043079
DrugFm 4-64

GAD2 MTOR SYP GPR162 ARF6

9.14e-0690715CID002733635
Drugacetylcholine

PRKD3 ADORA2A GAD2 ADRA1A SYP BCHE PLCH1 CHRM5

1.65e-05361718CID000000187
DrugThioperamide maleate [106243-16-7]; Up 200; 9.8uM; MCF7; HT_HG-U133A

PRKD3 ADORA2A TPP1 ATP10B MUC5B TMUB2

2.93e-051917163392_UP
DrugPHA-00851261E [724719-49-7]; Down 200; 1uM; MCF7; HT_HG-U133A

GAD2 PDE1C INPP5B CNTNAP2 ATP10B MUC5B

3.20e-051947163968_DN
Drugsodium

PRKD3 KCNT2 SLC12A4 MTOR ABCB8 PKD1 CNTNAP2 SLC6A15 BCHE SLC13A3 TAP2 ARF6

3.23e-059447112CID000000923
DrugRepaglinide [135062-02-1]; Down 200; 8.8uM; HL60; HT_HG-U133A

CD84 ADORA2A MYOF TPP1 MSH3 WDFY3

3.30e-051957166135_DN
DrugEthylnitrosourea

MTOR PKD1 PCDH15 SYP ADGRV1 CHRM5 GRPR

3.43e-05291717ctd:D005038
DrugPromazine hydrochloride [53-60-1]; Down 200; 12.4uM; PC3; HT_HG-U133A

MYOF GPR19 INPP5B CNTNAP2 ATP10B PLCH1

3.49e-051977163752_DN
DrugProcainamide hydrochloride [614-39-1]; Up 200; 14.8uM; MCF7; HT_HG-U133A

ADORA2A GAD2 PDE1C INPP5B CNTNAP2 CHRM5

3.59e-051987165663_UP
DrugDantrolene sodium salt [14663-23-1]; Up 200; 11.8uM; HL60; HT_HG-U133A

GAD2 MYOF ADRA1A AIPL1 ATP10B PLCH1

3.59e-051987162369_UP
DrugKetoprofen [22071-15-4]; Up 200; 15.8uM; MCF7; HT_HG-U133A

ADORA2A CNTNAP2 ATP10B SLC13A3 PLCH1 GRPR

3.59e-051987164751_UP
Drugpyrachlostrobin

CD84 ADORA2A MYOF LIPA SLC12A4 AEBP1 TPP1 BCHE ADGRV1 TAP2 AKAP12

3.98e-058117111ctd:C513428
DrugBP 897

ADORA2A ADRA1A BCHE

4.29e-0522713CID003038494
Drugcarbachol

PRKD3 ADORA2A PDE1A ADRA1A PKD1 BCHE PLCH1 PGA5 CHRM5 GRPR

5.21e-056887110CID000002551
DrugDipivefrin

ADRA1A BCHE

5.73e-054712DB00449
Diseaseautosomal dominant polycystic kidney disease (is_implicated_in)

MTOR PKD1

3.32e-054702DOID:898 (is_implicated_in)
DiseaseHyperkinesia, Generalized

ADORA2A CNTNAP2 BCHE

6.04e-0532703C0751217
DiseaseHyperkinesia

ADORA2A CNTNAP2 BCHE

6.04e-0532703C3887506
DiseaseCocaine Abuse

GAD2 ADRA1A BCHE CHRM5

2.41e-04127704C0009171
Diseaseadseverin measurement

BCHE DNMBP

2.47e-0410702EFO_0801358
DiseaseMajor Depressive Disorder

GAD2 ADRA1A MTOR CNTNAP2 SLC6A15

2.85e-04243705C1269683
DiseaseStevens-Johnson syndrome, toxic epidermal necrolysis, response to methazolamide

TAP2 BAG6

3.01e-0411702EFO_0004276, EFO_0004775, EFO_0020996
Diseaseresponse to calcium channel blocker

GPR19 PCDH15 SLC13A3

3.24e-0456703EFO_0007767
DiseaseCocaine Dependence

GAD2 ADRA1A BCHE CHRM5

3.40e-04139704C0600427
DiseaseUnipolar Depression

ADORA2A ADRA1A MTOR CNTNAP2 SLC6A15

3.81e-04259705C0041696
Diseasesusceptibility to hepatitis A infection measurement

DCHS2 SLC22A11 CNTNAP2

5.74e-0468703EFO_0008415
Diseaseepilepsy (implicated_via_orthology)

GAD2 KCNT2 SLC12A4 SLC13A3

6.20e-04163704DOID:1826 (implicated_via_orthology)
Diseaseautosomal recessive polycystic kidney disease (implicated_via_orthology)

MTOR PKD1

6.52e-0416702DOID:0110861 (implicated_via_orthology)
Diseasetype 1 diabetes mellitus (is_implicated_in)

GAD2 BCHE TAP2

1.10e-0385703DOID:9744 (is_implicated_in)
DiseaseNystagmus

ATP10B MSH3

1.13e-0321702HP_0000639
DiseaseSchizophrenia

ADORA2A GAD2 ADRA1A MTOR CNTNAP2 SYP TAP2 CHRM5

1.14e-03883708C0036341
Diseasegout

PDE1C SLC22A11 CNTNAP2 SLC13A3

1.23e-03196704EFO_0004274
Diseasecolorectal carcinoma (is_implicated_in)

MSH3 AKAP12

1.24e-0322702DOID:0080199 (is_implicated_in)
Diseasesorbitol measurement

AIPL1 SLC6A15

1.36e-0323702EFO_0010533
Diseasealcohol use disorder measurement, alcohol consumption measurement

SYT14 PCDH15 PLCH1

1.61e-0397703EFO_0007878, EFO_0009458
DiseaseDisorder of eye

TPP1 PCDH15 AIPL1 ADGRV1

1.64e-03212704C0015397
Diseasemethionine measurement

PCDH15 ADGRV1

1.74e-0326702EFO_0009771
Diseaseserum metabolite measurement

ADRA1A KCNT2 ABCB8 SLC22A11 PCDH15 SLC13A3 FCRL5 SLCO6A1

1.75e-03945708EFO_0005653
DiseaseVisual seizure

ADORA2A GAD2 BCHE

1.80e-03101703C0270824
DiseaseEpileptic drop attack

ADORA2A GAD2 BCHE

1.80e-03101703C0270846
DiseaseGeneralized seizures

ADORA2A GAD2 BCHE

1.80e-03101703C0234533
DiseaseClonic Seizures

ADORA2A GAD2 BCHE

1.80e-03101703C0234535
DiseaseVertiginous seizure

ADORA2A GAD2 BCHE

1.80e-03101703C0422855
DiseaseGustatory seizure

ADORA2A GAD2 BCHE

1.80e-03101703C0422854
DiseaseSeizures, Somatosensory

ADORA2A GAD2 BCHE

1.80e-03101703C0422850
DiseaseOlfactory seizure

ADORA2A GAD2 BCHE

1.80e-03101703C0422853
DiseaseSeizures, Auditory

ADORA2A GAD2 BCHE

1.80e-03101703C0422852
DiseaseGeneralized Absence Seizures

ADORA2A GAD2 BCHE

1.80e-03101703C4505436
DiseaseConvulsive Seizures

ADORA2A GAD2 BCHE

1.80e-03101703C0751494
DiseaseSeizures, Sensory

ADORA2A GAD2 BCHE

1.80e-03101703C0751496
DiseaseJacksonian Seizure

ADORA2A GAD2 BCHE

1.80e-03101703C0022333
DiseaseNon-epileptic convulsion

ADORA2A GAD2 BCHE

1.80e-03101703C0751056
DiseaseAtonic Absence Seizures

ADORA2A GAD2 BCHE

1.80e-03101703C0751123
DiseaseComplex partial seizures

ADORA2A GAD2 BCHE

1.80e-03101703C0149958
DiseaseSingle Seizure

ADORA2A GAD2 BCHE

1.80e-03101703C0751110
DiseaseEpileptic Seizures

ADORA2A GAD2 BCHE

1.80e-03101703C4317109
DiseaseNonepileptic Seizures

ADORA2A GAD2 BCHE

1.80e-03101703C3495874
DiseaseTonic Seizures

ADORA2A GAD2 BCHE

1.86e-03102703C0270844
DiseaseAbsence Seizures

ADORA2A GAD2 BCHE

1.86e-03102703C4316903
DiseaseConvulsions

ADORA2A GAD2 BCHE

1.86e-03102703C4048158
DiseaseSeizures, Focal

ADORA2A GAD2 BCHE

1.96e-03104703C0751495
DiseaseMyoclonic Seizures

ADORA2A GAD2 BCHE

1.96e-03104703C4317123
DiseaseTonic - clonic seizures

ADORA2A GAD2 BCHE

1.96e-03104703C0494475
DiseaseToxic Encephalitis

MTOR BCHE

2.16e-0329702C0154659
DiseaseNeurotoxicity Syndromes

MTOR BCHE

2.16e-0329702C0235032
Diseaseabdominal:gluteofemoral adipose tissue ratio measurement

TBX15 DNAH10

2.16e-0329702EFO_0803320
DiseaseEncephalopathy, Toxic

MTOR BCHE

2.16e-0329702C0149504
DiseaseCiliopathies

PCDH15 AIPL1 ADGRV1

2.30e-03110703C4277690
Diseasemalate measurement

SLC6A15 SLC13A3

2.31e-0330702EFO_0010508
Diseaseresting heart rate, chronic obstructive pulmonary disease

CTAGE1 ADGRV1

2.31e-0330702EFO_0000341, EFO_0004351
DiseaseGlioblastoma Multiforme

PRKD3 MTOR BCHE

2.36e-03111703C1621958

Protein segments in the cluster

PeptideGeneStartEntry
VTATVLINGTNFPFG

BAAT

251

Q14032
LTVFGGTVTAFLGIP

BCHE

46

P06276
TGELPNFITGSRVIF

AIPL1

21

Q9NZN9
LTSFPTFTSVGVLIV

CTAGE1

41

Q9HC47
LSPEFFTSVVQGVLS

BAG6

696

P46379
GVLAIPFAITISTGF

ADORA2A

56

P29274
GIVTPFVGTTAFSPL

ADGRG4

1666

Q8IZF6
FTQGKVVGQTTPESF

AKAP12

1106

Q02952
EIATGQAFPFTTVET

AEBP1

1136

Q8IUX7
TSTVLPFSAIFEVLG

ADRA1A

76

P35348
EFIPVTSLQSSTGFQ

GSDMD

21

P57764
VASTPFVLLQFTTGR

GPR19

116

Q15760
FVIDPNTGVITTQGF

FAT4

3241

Q6V0I7
FTQDVFPVQGTVVFG

ADGRV1

936

Q8WXG9
IFPTSGVILFTEGQV

ADGRV1

3701

Q8WXG9
DVTGQFPSSFVEIVT

DNMBP

46

Q6XZF7
DIDVFTFGTPINTIS

ATP10B

1221

O94823
PSSFFIVVQTGLGLQ

MUC5B

521

Q9HC84
GIGTPAQDFTVVFDT

PGA5

81

P0DJD9
LGVSSTTVGFVVPFT

APLNR

201

P35414
VGVQPATGEVVFDSF

MSH3

391

P20585
GFVPFLVSATAGTTV

GAD2

326

Q05329
DSLTGVPILVVSFFS

GPR162

281

Q16538
FTTDFKTGVLTVTGP

FAT2

2216

Q9NYQ8
GFGPQRSEVVSLFVT

FCRL5

546

Q96RD9
SQIGFIDFIVEPTFS

PDE1A

416

P54750
SQVGFIDFIVEPTFT

PDE1C

426

Q14123
IFLTTGIVVSAFGLP

LEPROTL1

71

O95214
SVGVIIYVSLSGTFP

PRKD3

761

O94806
PLISVSGVSQGFEFL

AP5M1

121

Q9H0R1
CIVTFSTVGFGDVTP

KCNT2

236

Q6UVM3
ELVIFAFGIVVGTSP

OR1I1

196

O60431
SGFISSPVQTAITFQ

OR2F1

151

Q13607
NVSSPEVFVLLGFST

OR2C3

6

Q8N628
GIGTPAQDFTVVFDT

PGA3

81

P0DJD8
VNVSFSSEGTPLAVF

DCHS2

2976

Q6V1P9
VNELTPVGTTIFTGF

PCDH15

156

Q96QU1
ELPTFTGVLFNTVGL

FRMPD3

391

Q5JV73
IPFIQLTSVGVSVFT

GRPR

116

P30550
TVFEGFTEGELTFQP

INPP5B

566

P32019
VSFSFDVGNGPVEIV

CNTNAP2

856

Q9UHC6
SISGSRFVGPFLQTV

DNAH10

1446

Q8IVF4
AVAGTSTIFAPTFVI

SLC22A11

181

Q9NSA0
TGVAIVTILFFFPSQ

SLC13A3

381

Q8WWT9
VFVVSFGDTPLTQSI

PKD1

2231

P98161
GIGTPAQDFTVVFDT

PGA4

81

P0DJD7
VGFISQEPVLFGTTI

ABCB8

551

Q9NUT2
TVPAVQGFFRSISLS

MTOR

1881

P42345
PVTSGLNTSVVFGFL

SYP

196

P08247
GATNGIVFLFTPNVT

SLC6A19

246

Q695T7
FGTIEGIVTPIVDTF

SLC6A15

476

Q9H2J7
VSPEAVGFLSAVGVF

SYT14

21

Q8NB59
AVASSTFLGVIPQFV

SFXN4

171

Q6P4A7
VLFTFPGNLVTSVAG

TCAF1

166

Q9Y4C2
GVKTFNFPETVFTTV

TBX15

266

Q96SF7
IFTVNGILGESVTFP

CD84

26

Q9UIB8
FSTLIFSGFSGVPIV

SLCO6A1

586

Q86UG4
VVSVGQEPVLFSGSV

TAP2

546

Q03519
VTRVGTFILVGFPTA

OR6B3

6

Q8NGW1
IATSFTVLVGIFFPS

SLC12A4

416

Q9UP95
IIIGAFFIPEGTFTT

SERINC1

136

Q9NRX5
QFLSEPTITFGTAIA

CHRM5

186

P08912
GQSVTTIPTVGFNVE

ARF6

36

P62330
QQITVISPFSFSIGD

UBA6

261

A0AVT1
TFIFGVPASSGTVVS

WDFY3

1816

Q8IZQ1
FTAPATVSLVGVTVF

TMUB2

296

Q71RG4
TEITIRGFGFSTIPA

PKHD1L1

1346

Q86WI1
FVGQRTVTFSSLVPG

PLCH1

821

Q4KWH8
SEGFIPLTFTATQEI

WDCP

656

Q9H6R7
TTVGGTSFQEPFLIT

TPP1

386

O14773
GTTIGFIAFSQIPEL

LIPA

176

P38571
VNTGETEVGFVPTFG

MYOF

486

Q9NZM1