Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	ATP-dependent activity	ABCC3 MYH6 MYH7 MYH13 RSF1 MYO18A BTAF1 FANCM ACSL1 MLH3 STARD9 SNRNP200 TDRD12	1.82e-05	614	104	13	GO:0140657
GeneOntologyMolecularFunction	histone modifying activity	SLK FBLL1 KDM5A KMT2C BRCA2 MCM3AP TAF1 TAF1L	2.65e-05	229	104	8	GO:0140993
GeneOntologyMolecularFunction	histone acetyltransferase activity	BRCA2 MCM3AP TAF1 TAF1L	1.44e-04	51	104	4	GO:0004402
GeneOntologyMolecularFunction	cytoskeletal protein binding	MYH6 MYH7 MYH13 SPTBN1 MYO18A GBP3 PSTPIP1 NEFH BRCA2 STARD9 NISCH CCSER2 DIAPH1 CEP295 WDR1 TTLL13	1.74e-04	1099	104	16	GO:0008092
GeneOntologyMolecularFunction	actin filament binding	MYH6 MYH7 MYH13 SPTBN1 MYO18A PSTPIP1 WDR1	1.87e-04	227	104	7	GO:0051015
GeneOntologyMolecularFunction	peptide-lysine-N-acetyltransferase activity	BRCA2 MCM3AP TAF1 TAF1L	1.93e-04	55	104	4	GO:0061733
GeneOntologyMolecularFunction	ribonucleoside triphosphate phosphatase activity	ABCC3 MYH7 RSF1 MYO18A GBP3 BTAF1 FANCM RGS4 MLH3 GNA14 RAB43 SNRNP200 TDRD12	1.93e-04	775	104	13	GO:0017111
GeneOntologyMolecularFunction	acetyltransferase activity	DBT BRCA2 MCM3AP TAF1 TAF1L	2.13e-04	104	104	5	GO:0016407
GeneOntologyMolecularFunction	H3K27me3 modified histone binding	TAF1 TAF1L	2.66e-04	5	104	2	GO:0061628
GeneOntologyMolecularFunction	peptide N-acetyltransferase activity	BRCA2 MCM3AP TAF1 TAF1L	2.71e-04	60	104	4	GO:0034212
GeneOntologyMolecularFunction	nucleoside-triphosphatase regulator activity	STARD8 MYCBP2 GBP3 RGS4 PREX2 SIRPG SYDE2 SBF2 RPGR ARHGAP20	3.15e-04	507	104	10	GO:0060589
GeneOntologyMolecularFunction	GTPase regulator activity	STARD8 MYCBP2 GBP3 RGS4 PREX2 SIRPG SYDE2 SBF2 RPGR ARHGAP20	3.15e-04	507	104	10	GO:0030695
GeneOntologyMolecularFunction	cytoskeletal motor activity	MYH6 MYH7 MYH13 MYO18A STARD9	3.82e-04	118	104	5	GO:0003774
GeneOntologyMolecularFunction	pyrophosphatase activity	ABCC3 MYH7 RSF1 MYO18A GBP3 BTAF1 FANCM RGS4 MLH3 GNA14 RAB43 SNRNP200 TDRD12	4.15e-04	839	104	13	GO:0016462
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides	ABCC3 MYH7 RSF1 MYO18A GBP3 BTAF1 FANCM RGS4 MLH3 GNA14 RAB43 SNRNP200 TDRD12	4.20e-04	840	104	13	GO:0016817
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	ABCC3 MYH7 RSF1 MYO18A GBP3 BTAF1 FANCM RGS4 MLH3 GNA14 RAB43 SNRNP200 TDRD12	4.20e-04	840	104	13	GO:0016818
GeneOntologyMolecularFunction	histone binding	SFMBT1 KDM5A RSF1 NASP MCM3AP TAF1 TAF1L	4.76e-04	265	104	7	GO:0042393
GeneOntologyMolecularFunction	ATP hydrolysis activity	ABCC3 MYH7 RSF1 MYO18A BTAF1 FANCM MLH3 SNRNP200 TDRD12	4.97e-04	441	104	9	GO:0016887
GeneOntologyMolecularFunction	ATP-dependent activity, acting on DNA	RSF1 MYO18A BTAF1 FANCM MLH3	5.35e-04	127	104	5	GO:0008094
GeneOntologyMolecularFunction	TBP-class protein binding	BTAF1 TAF1 TAF1L	6.68e-04	33	104	3	GO:0017025
GeneOntologyMolecularFunction	N-acetyltransferase activity	BRCA2 MCM3AP TAF1 TAF1L	7.37e-04	78	104	4	GO:0008080
GeneOntologyMolecularFunction	actin binding	MYH6 MYH7 MYH13 SPTBN1 MYO18A GBP3 PSTPIP1 DIAPH1 WDR1	8.94e-04	479	104	9	GO:0003779
GeneOntologyMolecularFunction	RNA polymerase I general transcription initiation factor activity	TAF1 TAF1L	9.44e-04	9	104	2	GO:0001181
GeneOntologyMolecularFunction	microfilament motor activity	MYH6 MYH7 MYH13	1.01e-03	38	104	3	GO:0000146
GeneOntologyMolecularFunction	N-acyltransferase activity	BRCA2 MCM3AP TAF1 TAF1L	2.00e-03	102	104	4	GO:0016410
GeneOntologyMolecularFunction	enzyme regulator activity	STARD8 MYCBP2 KDM5A GBP3 ANKLE2 RGS4 PREX2 SIRPG ACSL1 AFAP1L2 SYDE2 SBF2 RPGR ARHGAP20 KNG1 PINK1	2.67e-03	1418	104	16	GO:0030234
GeneOntologyMolecularFunction	histone H3 acetyltransferase activity	BRCA2 MCM3AP	2.70e-03	15	104	2	GO:0010484
GeneOntologyBiologicalProcess	microtubule cytoskeleton organization	SLK SUN1 DDB1 DNAAF5 NEFH BRCA2 STARD9 GCC2 NISCH CCSER2 SENP6 CFAP206 SMN1 CEP295 TTLL13 CCDC40	5.46e-07	720	103	16	GO:0000226
GeneOntologyBiologicalProcess	microtubule-based process	SLK SUN1 TTLL8 DDB1 DNAAF5 NEFH BRCA2 STARD9 GCC2 NISCH CCSER2 DIAPH1 SENP6 CFAP206 SMN1 CEP295 RPGR TTLL13 CCDC40	1.08e-06	1058	103	19	GO:0007017
GeneOntologyCellularComponent	myosin filament	MYH6 MYH7 MYH13 MYO18A	6.75e-06	25	104	4	GO:0032982
GeneOntologyCellularComponent	myosin II complex	MYH6 MYH7 MYH13 MYO18A	1.08e-05	28	104	4	GO:0016460
GeneOntologyCellularComponent	muscle myosin complex	MYH6 MYH7 MYH13	6.39e-05	16	104	3	GO:0005859
GeneOntologyCellularComponent	myosin complex	MYH6 MYH7 MYH13 MYO18A	2.13e-04	59	104	4	GO:0016459
Domain	Myosin_tail_1	MYH6 MYH7 MYH13 MYO18A	2.52e-06	18	103	4	PF01576
Domain	Myosin_tail	MYH6 MYH7 MYH13 MYO18A	2.52e-06	18	103	4	IPR002928
Domain	Myosin-like_IQ_dom	MYH6 MYH7 MYH13 MYO18A	3.17e-06	19	103	4	IPR027401
Domain	-	MYH6 MYH7 MYH13 MYO18A	3.17e-06	19	103	4	4.10.270.10
Domain	TFIID_sub1_DUF3591	TAF1 TAF1L	3.01e-05	2	103	2	IPR022591
Domain	TBP-binding	TAF1 TAF1L	3.01e-05	2	103	2	PF09247
Domain	DUF3591	TAF1 TAF1L	3.01e-05	2	103	2	PF12157
Domain	TAF_II_230-bd	TAF1 TAF1L	3.01e-05	2	103	2	IPR009067
Domain	-	TAF1 TAF1L	3.01e-05	2	103	2	1.10.1100.10
Domain	TAF1_animal	TAF1 TAF1L	3.01e-05	2	103	2	IPR011177
Domain	Myosin_head_motor_dom	MYH6 MYH7 MYH13 MYO18A	5.57e-05	38	103	4	IPR001609
Domain	MYOSIN_MOTOR	MYH6 MYH7 MYH13 MYO18A	5.57e-05	38	103	4	PS51456
Domain	Myosin_head	MYH6 MYH7 MYH13 MYO18A	5.57e-05	38	103	4	PF00063
Domain	MYSc	MYH6 MYH7 MYH13 MYO18A	5.57e-05	38	103	4	SM00242
Domain	Myosin_N	MYH6 MYH7 MYH13	7.06e-05	15	103	3	PF02736
Domain	Myosin_N	MYH6 MYH7 MYH13	7.06e-05	15	103	3	IPR004009
Domain	P-loop_NTPase	ABCC3 MYH6 MYH7 MYH13 MYO18A GBP3 BTAF1 LRRK1 FANCM GNA14 STARD9 RAB43 SNRNP200 TDRD12	2.28e-04	848	103	14	IPR027417
Domain	IQ	MYH6 MYH7 MYH13 MYO18A	1.05e-03	81	103	4	SM00015
Domain	PHD	KDM5A RSF1 KMT2C RAI1	1.49e-03	89	103	4	SM00249
Domain	IQ_motif_EF-hand-BS	MYH6 MYH7 MYH13 MYO18A	1.55e-03	90	103	4	IPR000048
Domain	Znf_PHD	KDM5A RSF1 KMT2C RAI1	1.61e-03	91	103	4	IPR001965
Domain	IQ	MYH6 MYH7 MYH13 MYO18A	1.75e-03	93	103	4	PS50096
Domain	ZF_PHD_2	KDM5A RSF1 KMT2C RAI1	1.89e-03	95	103	4	PS50016
Domain	ZF_PHD_1	KDM5A RSF1 KMT2C RAI1	1.96e-03	96	103	4	PS01359
Domain	HEAT	BTAF1 DNAAF5 MMS19	2.35e-03	48	103	3	PF02985
Domain	START_lipid-bd_dom	STARD8 STARD9	3.02e-03	15	103	2	IPR002913
Domain	START	STARD8 STARD9	3.02e-03	15	103	2	PF01852
Domain	START	STARD8 STARD9	3.02e-03	15	103	2	PS50848
Domain	HEAT	BTAF1 DNAAF5 MMS19	4.03e-03	58	103	3	IPR000357
Domain	RhoGAP	STARD8 SYDE2 ARHGAP20	4.87e-03	62	103	3	SM00324
Domain	RhoGAP	STARD8 SYDE2 ARHGAP20	5.09e-03	63	103	3	PF00620
Domain	RhoGAP_dom	STARD8 SYDE2 ARHGAP20	5.32e-03	64	103	3	IPR000198
Domain	RHOGAP	STARD8 SYDE2 ARHGAP20	5.32e-03	64	103	3	PS50238
Domain	-	STARD8 SYDE2 ARHGAP20	5.32e-03	64	103	3	1.10.555.10
Domain	RCC1	MYCBP2 RPGR	5.36e-03	20	103	2	PF00415
Pubmed	Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.	EPS15 RNF169 STARD8 NASP NUP214 CCDC12 DDB1 PREPL PREX2 LUC7L2 SYDE2 NISCH SMN1 NUP93 WDR1 ARHGAP20 CPSF3	2.28e-09	916	105	17	32203420
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	ABCC3 FRAS1 HIVEP2 MYCBP2 L1CAM PSMB10 BTAF1 NUP214 LRRK1 NHSL1 KMT2C SLC12A4 NISCH ZNF408 SBF2 RAB43 MCM3AP RAI1	5.61e-09	1105	105	18	35748872
Pubmed	Tumor suppressor BAP1 nuclear import is governed by transportin-1.	EPS15 MYH7 SLK MYCBP2 SPTBN1 MYO18A NASP DDB1 PREPL LUC7L2 NISCH DIAPH1 SMN1 MMS19 NUP93 WDR1 SNRNP200	6.28e-08	1149	105	17	35446349
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	SUN1 LRRK1 ANKLE2 PREPL KMT2C USP38 CCSER2 SENP6 TMEM131L NUP93 ARHGAP20 RAI1	7.34e-08	529	105	12	14621295
Pubmed	Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis.	SLK SPTBN1 SUN1 BSDC1 NASP NUP214 ANKLE2 ITPR1 NBAS SLC12A4 GCC2 TMEM131L	1.58e-07	568	105	12	37774976
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	SFMBT1 EPS15 ZNF280D MYCBP2 KDM5A NUP214 BRCA2 LUC7L2 GCC2 TAF1	5.90e-07	418	105	10	34709266
Pubmed	Interaction network of human early embryonic transcription factors.	HIVEP2 KDM5A NUP214 DBT KMT2C MCM3AP ALB TAF1 RAI1	1.26e-06	351	105	9	38297188
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	ITGAE FABP7 KMT2C AFAP1L2 SYDE2 ZNF408 MCM3AP CEP295 ALB ARHGAP20 SNRNP200 RAI1	2.39e-06	736	105	12	29676528
Pubmed	Network organization of the huntingtin proteomic interactome in mammalian brain.	GPD1 MYH6 SPTBN1 MYO18A RGS4 ITPR1 SIRPG ACSL1 NEFH BRCA2 NUP93	2.94e-06	621	105	11	22794259
Pubmed	HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.	MYH7 CCDC186 SPTBN1 MYO18A NASP NUP214 ITPR1 SLC12A4 BRCA2 ALB NUP93 SNRNP200	3.06e-06	754	105	12	35906200
Pubmed	Cleavage of human and mouse cytoskeletal and sarcomeric proteins by human immunodeficiency virus type 1 protease. Actin, desmin, myosin, and tropomyosin.	MYH6 MYH7 MYH13	5.77e-06	12	105	3	8424456
Pubmed	Protein interactome mining defines melatonin MT1 receptors as integral component of presynaptic protein complexes of neurons.	EPS15 MYH7 HIVEP2 NASP KMT2C CRYM SLC12A4 MMS19	6.33e-06	322	105	8	26514267
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	EPS15 SLK MYCBP2 KDM5A SPTBN1 DDB1 PREPL SIRPG NEFH NISCH DIAPH1 WDR1 RAI1	6.91e-06	963	105	13	28671696
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	SFMBT1 RNF169 KDM5A NUP214 CCDC12 FANCM DDB1 KMT2C PRDM11 LUC7L2 NUP93 TAF1L SNRNP200 CPSF3 RAI1	8.07e-06	1294	105	15	30804502
Pubmed	Tagging genes with cassette-exchange sites.	RNF169 SUN1 BSDC1 CCDC12 ANKLE2 KMT2C MMS19 RPGR	8.45e-06	335	105	8	15741177
Pubmed	Reversible epigenetic modifications of the two cardiac myosin heavy chain genes during changes in expression.	MYH6 MYH7	9.03e-06	2	105	2	21526716
Pubmed	Characterization of human cardiac myosin heavy chain genes.	MYH6 MYH7	9.03e-06	2	105	2	2726733
Pubmed	Human cardiac myosin heavy chain genes and their linkage in the genome.	MYH6 MYH7	9.03e-06	2	105	2	3037493
Pubmed	β-myosin heavy chain is induced by pressure overload in a minor subpopulation of smaller mouse cardiac myocytes.	MYH6 MYH7	9.03e-06	2	105	2	21778428
Pubmed	Structural organization of the human cardiac alpha-myosin heavy chain gene (MYH6).	MYH6 MYH7	9.03e-06	2	105	2	8307559
Pubmed	Molecular cloning and characterization of human cardiac alpha- and beta-form myosin heavy chain complementary DNA clones. Regulation of expression during development and pressure overload in human atrium.	MYH6 MYH7	9.03e-06	2	105	2	2969919
Pubmed	Taf1 knockout is lethal in embryonic male mice and heterozygous females show weight and movement disorders.	TAF1 TAF1L	9.03e-06	2	105	2	38804708
Pubmed	Distribution and structure-function relationship of myosin heavy chain isoforms in the adult mouse heart.	MYH6 MYH7	9.03e-06	2	105	2	17575272
Pubmed	Neonatal cardiomyopathy in mice homozygous for the Arg403Gln mutation in the alpha cardiac myosin heavy chain gene.	MYH6 MYH7	9.03e-06	2	105	2	9884344
Pubmed	[Interaction of SENP6 with PINK1 Promotes Temozolomide Resistance in Neuroglioma Cells via Inducing the Mitophagy].	SENP6 PINK1	9.03e-06	2	105	2	38062972
Pubmed	Role of microtubules versus myosin heavy chain isoforms in contractile dysfunction of hypertrophied murine cardiocytes.	MYH6 MYH7	9.03e-06	2	105	2	12750067
Pubmed	Sustained expression of a neuron-specific isoform of the Taf1 gene in development stages and aging in mice.	TAF1 TAF1L	9.03e-06	2	105	2	22842574
Pubmed	Frameshift Mutations in the Mononucleotide Repeats of TAF1 and TAF1L Genes in Gastric and Colorectal Cancers with Regional Heterogeneity.	TAF1 TAF1L	9.03e-06	2	105	2	27571988
Pubmed	Striatal Cholinergic Dysregulation after Neonatal Decrease in X-Linked Dystonia Parkinsonism-Related TAF1 Isoforms.	TAF1 TAF1L	9.03e-06	2	105	2	34403156
Pubmed	Transgenic mouse α- and β-cardiac myosins containing the R403Q mutation show isoform-dependent transient kinetic differences.	MYH6 MYH7	9.03e-06	2	105	2	23580644
Pubmed	RGS4 inhibits platelet-activating factor receptor phosphorylation and cellular responses.	PTAFR RGS4	9.03e-06	2	105	2	11297424
Pubmed	β-Myosin heavy chain variant Val606Met causes very mild hypertrophic cardiomyopathy in mice, but exacerbates HCM phenotypes in mice carrying other HCM mutations.	MYH6 MYH7	9.03e-06	2	105	2	24829265
Pubmed	Cardiac myosin heavy chain mRNA expression and myocardial function in the mouse heart.	MYH6 MYH7	9.03e-06	2	105	2	2036722
Pubmed	Ensemble force changes that result from human cardiac myosin mutations and a small-molecule effector.	MYH6 MYH7	9.03e-06	2	105	2	25937279
Pubmed	Myocardial contraction is 5-fold more economical in ventricular than in atrial human tissue.	MYH6 MYH7	9.03e-06	2	105	2	15621050
Pubmed	Functional effects of the hypertrophic cardiomyopathy R403Q mutation are different in an alpha- or beta-myosin heavy chain backbone.	MYH6 MYH7	9.03e-06	2	105	2	18480046
Pubmed	Analysis of albumin-associated peptides and proteins from ovarian cancer patients.	BRCA2 ALB	9.03e-06	2	105	2	16099937
Pubmed	Murine pulmonary myocardium: developmental analysis of cardiac gene expression.	MYH6 MYH7	9.03e-06	2	105	2	7919499
Pubmed	Long-Read Sequence Confirmed a Large Deletion Including MYH6 and MYH7 in an Infant of Atrial Septal Defect and Atrial Arrhythmias.	MYH6 MYH7	9.03e-06	2	105	2	34384224
Pubmed	Human cardiac myosin heavy chain gene mapped within chromosome region 14q11.2----q13.	MYH6 MYH7	9.03e-06	2	105	2	2494889
Pubmed	MCM3AP, a novel HBV integration site in hepatocellular carcinoma and its implication in hepatocarcinogenesis.	MCM3AP CCDC40	9.03e-06	2	105	2	20714864
Pubmed	All-atom molecular dynamics simulations of actin-myosin interactions: a comparative study of cardiac α myosin, β myosin, and fast skeletal muscle myosin.	MYH6 MYH7	9.03e-06	2	105	2	24224850
Pubmed	Myosin heavy chain composition and the economy of contraction in healthy and diseased human myocardium.	MYH6 MYH7	9.03e-06	2	105	2	16088376
Pubmed	Complete sequence of human cardiac alpha-myosin heavy chain gene and amino acid comparison to other myosins based on structural and functional differences.	MYH6 MYH7	9.03e-06	2	105	2	1776652
Pubmed	TAFII250, Egr-1, and D-type cyclin expression in mice and neonatal rat cardiomyocytes treated with doxorubicin.	TAF1 TAF1L	9.03e-06	2	105	2	10070062
Pubmed	Diastolic dysfunction and altered energetics in the alphaMHC403/+ mouse model of familial hypertrophic cardiomyopathy.	MYH6 MYH7	9.03e-06	2	105	2	9541509
Pubmed	Hepatitis B virus X protein interacts with a probable cellular DNA repair protein.	RSF1 DDB1	9.03e-06	2	105	2	7815490
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	EPS15 FRAS1 MYCBP2 SPTBN1 SUN1 MYO18A DBT ANKLE2 DDB1 PREPL ITPR1 NBAS NISCH CCSER2 TMEM131L SNRNP200	9.92e-06	1487	105	16	33957083
Pubmed	Defining the human deubiquitinating enzyme interaction landscape.	USP30 SLK HIVEP2 MYCBP2 NUP214 DBT PREPL USP38 GCC2 MMS19 ALB NUP93 SNRNP200	1.09e-05	1005	105	13	19615732
Pubmed	Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.	SPTBN1 BTAF1 DDB1 GNA14 LUC7L2 DIAPH1 SMN1 NUP93 SNRNP200 CPSF3	1.11e-05	582	105	10	20467437
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	EPS15 RNF169 MYCBP2 SUN1 NUP214 DDB1 NBAS DIAPH1 TMEM131L CEP295 CPSF3	1.40e-05	733	105	11	34672954
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	RNF169 ZNF280D KDM5A RSF1 NASP BTAF1 DDB1 SENP6 TAF1 RAI1	1.61e-05	608	105	10	36089195
Pubmed	CTDP1 regulates breast cancer survival and DNA repair through BRCT-specific interactions with FANCI.	BTAF1 ITPR1 ACSL1 MCM3AP DIAPH1	1.65e-05	104	105	5	31240132
Pubmed	A human MAP kinase interactome.	HIVEP2 CCDC186 SPTBN1 MYO18A NUP214 KMT2C MCM3AP TAF1 SNRNP200	1.73e-05	486	105	9	20936779
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	MYH13 SPTBN1 NASP NUP214 DDB1 KMT2C LUC7L2 ZNF408 RAI1	2.06e-05	497	105	9	36774506
Pubmed	A cardiomyocyte-specific Wdr1 knockout demonstrates essential functional roles for actin disassembly during myocardial growth and maintenance in mice.	MYH6 MYH7 WDR1	2.11e-05	18	105	3	24840128
Pubmed	Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.	RNF169 SLK MYCBP2 RSF1 NASP DBT DIAPH1 ALB CPSF3 RAI1	2.67e-05	645	105	10	25281560
Pubmed	Endogenous retinoic acid signaling colocalizes with advanced expression of the adult smooth muscle myosin heavy chain isoform during development of the ductus arteriosus.	MYH6 MYH7	2.70e-05	3	105	2	8620598
Pubmed	Heterogeneous myocyte enhancer factor-2 (Mef2) activation in myocytes predicts focal scarring in hypertrophic cardiomyopathy.	MYH6 MYH7	2.70e-05	3	105	2	20923879
Pubmed	Mouse embryonic stem cells express the cardiac myosin heavy chain genes during development in vitro.	MYH6 MYH7	2.70e-05	3	105	2	1694848
Pubmed	Discordant on/off switching of gene expression in myocytes during cardiac hypertrophy in vivo.	MYH6 MYH7	2.70e-05	3	105	2	18755891
Pubmed	Dual role of USP30 in controlling basal pexophagy and mitophagy.	USP30 PINK1	2.70e-05	3	105	2	29895712
Pubmed	Conotruncal anomalies in the trisomy 16 mouse: an immunohistochemical analysis with emphasis on the involvement of the neural crest.	MYH6 MYH7	2.70e-05	3	105	2	11066038
Pubmed	HIV-1 Tat reduces nephrin in human podocytes: a potential mechanism for enhanced glomerular permeability in HIV-associated nephropathy.	PTAFR ALB	2.70e-05	3	105	2	17301560
Pubmed	Severe heart failure and early mortality in a double-mutation mouse model of familial hypertrophic cardiomyopathy.	MYH6 MYH7	2.70e-05	3	105	2	18362229
Pubmed	Myosin heavy chain gene expression in mouse embryoid bodies. An in vitro developmental study.	MYH6 MYH7	2.70e-05	3	105	2	1939265
Pubmed	Regulated expression of TAF1 in 1-cell mouse embryos.	TAF1 TAF1L	2.70e-05	3	105	2	16822332
Pubmed	Albumin Overload and PINK1/Parkin Signaling-Related Mitophagy in Renal Tubular Epithelial Cells.	ALB PINK1	2.70e-05	3	105	2	29494565
Pubmed	Mutation in myosin heavy chain 6 causes atrial septal defect.	MYH6 MYH7	2.70e-05	3	105	2	15735645
Pubmed	TAFII55 binding to TAFII250 inhibits its acetyltransferase activity.	TAF1 TAF1L	2.70e-05	3	105	2	11592977
Pubmed	The mitochondrial deubiquitinase USP30 opposes parkin-mediated mitophagy.	USP30 PINK1	2.70e-05	3	105	2	24896179
Pubmed	Functional substitution for TAF(II)250 by a retroposed homolog that is expressed in human spermatogenesis.	TAF1 TAF1L	2.70e-05	3	105	2	12217962
Pubmed	TAF7: a possible transcription initiation check-point regulator.	TAF1 TAF1L	2.70e-05	3	105	2	16407123
Pubmed	USP30 sets a trigger threshold for PINK1-PARKIN amplification of mitochondrial ubiquitylation.	USP30 PINK1	2.70e-05	3	105	2	32636217
Pubmed	The effects of slow skeletal troponin I expression in the murine myocardium are influenced by development-related shifts in myosin heavy chain isoform.	MYH6 MYH7	2.70e-05	3	105	2	22966157
Pubmed	New nomenclature for chromatin-modifying enzymes.	KDM5A KMT2C TAF1 TAF1L	2.74e-05	57	105	4	18022353
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	MYCBP2 SPTBN1 RSF1 NUP214 DDB1 MCM3AP NUP93 SNRNP200 CPSF3 RAI1	2.96e-05	653	105	10	22586326
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	FBLL1 KDM5A RSF1 DBT DDB1 MLH3 LUC7L2 MCM3AP DIAPH1 MMS19 CEP295 TAF1 RAI1	3.25e-05	1116	105	13	31753913
Pubmed	The TIP60 Complex Is a Conserved Coactivator of HIF1A.	BTAF1 DDB1 MMS19 NUP93 SNRNP200	3.30e-05	120	105	5	27320910
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	FRAS1 SLK NUP214 NEFH STARD9 GCC2 NISCH MCM3AP	3.41e-05	407	105	8	12693553
Pubmed	A directed protein interaction network for investigating intracellular signal transduction.	CCDC186 PSMB10 NASP KMT2C CRYM LUC7L2 MCM3AP CCSER2 SMN1 ALB WDR1 ZNF282 RAI1	3.49e-05	1124	105	13	21900206
Pubmed	Defining the membrane proteome of NK cells.	EPS15 GLT8D1 MYCBP2 MYO18A PSTPIP1 ANKLE2 ITPR1 ACSL1 NBAS GCC2 NISCH MMS19 NUP93	5.17e-05	1168	105	13	19946888
Pubmed	Identification of cellular and genetic drivers of breast cancer heterogeneity in genetically engineered mouse tumour models.	BRCA2 PINK1	5.40e-05	4	105	2	24615332
Pubmed	Giant ankyrin-B mediates transduction of axon guidance and collateral branch pruning factor sema 3A.	SPTBN1 L1CAM	5.40e-05	4	105	2	34812142
Pubmed	Murine cardiac progenitor cells require visceral embryonic endoderm and primitive streak for terminal differentiation.	MYH6 MYH7	5.40e-05	4	105	2	9389458
Pubmed	A tight cluster of five unrelated human genes on chromosome 16q22.1.	PSMB10 SLC12A4	5.40e-05	4	105	2	8268911
Pubmed	Altered cardiac phenotype in transgenic mice carrying the delta337 threonine thyroid hormone receptor beta mutant derived from the S family.	MYH6 MYH7	5.40e-05	4	105	2	9927321
Pubmed	CRL4s: the CUL4-RING E3 ubiquitin ligases.	DDB1 WDR1	5.40e-05	4	105	2	19818632
Pubmed	Combined cardiomyocyte PKCδ and PKCε gene deletion uncovers their central role in restraining developmental and reactive heart growth.	MYH6 MYH7	5.40e-05	4	105	2	25900833
Pubmed	Changes in expression of nonmuscle myosin heavy chain isoforms during muscle and nonmuscle tissue development.	MYH6 MYH7	5.40e-05	4	105	2	8482409
Pubmed	Sarcomere protein gene mutations in hypertrophic cardiomyopathy of the elderly.	MYH6 MYH7	5.40e-05	4	105	2	11815426
Pubmed	Androgen receptor is expressed in mouse cardiomyocytes at prenatal and early postnatal developmental stages.	MYH6 MYH7	5.40e-05	4	105	2	28806941
Pubmed	Mutational analysis of FANCL, FANCM and the recently identified FANCI suggests that among the 13 known Fanconi Anemia genes, only FANCD1/BRCA2 plays a major role in high-risk breast cancer predisposition.	FANCM BRCA2	5.40e-05	4	105	2	19737859
Pubmed	Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.	MYCBP2 NUP214 ITPR1 NISCH CCSER2 SMN1 MMS19 NUP93	5.89e-05	440	105	8	34244565
Pubmed	Hypertonicity-responsive ubiquitin ligase RNF183 promotes Na, K-ATPase lysosomal degradation through ubiquitination of its β1 subunit.	EPS15 SLK BSDC1 NASP STARD9 NISCH MMS19 CPSF3	6.78e-05	449	105	8	31732153
Pubmed	Proteome-wide analysis of USP14 substrates revealed its role in hepatosteatosis via stabilization of FASN.	SPTBN1 MYO18A DDB1 LUC7L2 NISCH WDR1 SNRNP200	7.20e-05	334	105	7	30425250
Pubmed	METTL3 protects METTL14 from STUB1-mediated degradation to maintain m6 A homeostasis.	SPTBN1 NASP ITGAE DDB1 MMS19 SNRNP200	7.48e-05	231	105	6	36597993
Pubmed	Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation.	SUN1 NUP214 DNAAF5 KMT2C LUC7L2 MCM3AP NUP93 RAI1	7.66e-05	457	105	8	32344865
Pubmed	Functional proteomics mapping of a human signaling pathway.	EPS15 MYCBP2 SPTBN1 ANKLE2 DDB1 SLC12A4 LUC7L2 MCM3AP DIAPH1	7.86e-05	591	105	9	15231748
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	RNF169 MYCBP2 SPTBN1 SUN1 DBT ANKLE2 ITPR1 NHSL1 SLC12A4 SBF2 NUP93 CPSF3	7.91e-05	1049	105	12	27880917
Cytoband	3p21.1	SFMBT1 GLT8D1 NISCH	1.25e-04	42	105	3	3p21.1
GeneFamily	Myosin heavy chains	MYH6 MYH7 MYH13	1.70e-05	15	62	3	1098
GeneFamily	X-linked mental retardation\|RNA helicases	FANCM SNRNP200	6.24e-04	11	62	2	1168
GeneFamily	Tubulin tyrosine ligase family	TTLL8 TTLL13	1.03e-03	14	62	2	779
GeneFamily	StAR related lipid transfer domain containing	STARD8 STARD9	1.18e-03	15	62	2	759
GeneFamily	Zinc fingers C2H2-type\|PR/SET domain family	PRDM11 ZNF408	1.52e-03	17	62	2	1197
GeneFamily	EF-hand domain containing\|Nucleotide excision repair\|Transcription and export complex 2	DDB1 MMS19	1.71e-03	18	62	2	1269
GeneFamily	Ring finger proteins\|Fanconi anemia complementation groups\|Protein phosphatase 1 regulatory subunits\|BRCA1 A complex\|BRCA1 B complex\|BRCA1 C complex	FANCM BRCA2	2.11e-03	20	62	2	548
GeneFamily	PHD finger proteins	KDM5A RSF1 KMT2C	3.65e-03	90	62	3	88
GeneFamily	Nucleoporins	NUP214 NUP93	5.37e-03	32	62	2	1051
GeneFamily	Tudor domain containing	SMN1 TDRD12	7.13e-03	37	62	2	780
Coexpression	BUSSLINGER_GASTRIC_IMMUNE_CELLS	EPS15 SLK HIVEP2 MYCBP2 KDM5A RSF1 PSMB10 GBP3 BTAF1 PSTPIP1 ITGAE ANKLE2 ITPR1 SIRPG KMT2C CCSER2 DIAPH1 SENP6 TMEM131L WDR1 SNRNP200	3.41e-07	1492	104	21	M40023
Coexpression	GSE360_L_DONOVANI_VS_B_MALAYI_LOW_DOSE_DC_DN	NASP PREPL BRCA2 NISCH MCM3AP DIAPH1 WDR1 SNRNP200	1.38e-06	200	104	8	M5204
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	SFMBT1 EPS15 SLK HIVEP2 MYCBP2 KDM5A BTAF1 ANKLE2 ITPR1 NBAS BRCA2 GCC2 CCSER2 TMEM131L RPGR	1.45e-06	856	104	15	M4500
Coexpression	GSE26343_WT_VS_NFAT5_KO_MACROPHAGE_UP	RNF169 SLK MYCBP2 SPTBN1 L1CAM ITGAE MMS19	1.54e-05	200	104	7	M8644
Coexpression	LASTOWSKA_NEUROBLASTOMA_COPY_NUMBER_DN	EPS15 RNF169 GLT8D1 CCDC186 RSF1 BSDC1 NASP BTAF1 PTAFR CCDC12 CCSER2 CEP295 PINK1	1.88e-05	807	104	13	M14594
Coexpression	CUI_TCF21_TARGETS_2_DN	SFMBT1 SLK HIVEP2 STARD8 MYO18A BTAF1 DBT PREX2 SIRPG KMT2C AFAP1L2 LUC7L2 KNG1	5.05e-05	888	104	13	MM1018
Coexpression	GSE7568_CTRL_VS_3H_TGFB_TREATED_MACROPHAGES_WITH_IL4_AND_DEXAMETHASONE_DN	EPS15 NUP214 ANKLE2 GCC2 SYDE2 NISCH	5.54e-05	167	104	6	M361
Coexpression	GSE33292_DN3_THYMOCYTE_VS_TCELL_LYMPHOMA_FROM_TCF1_KO_UP	HIVEP2 MYCBP2 NBAS GCC2 SMN1 NUP93	6.74e-05	173	104	6	M9425
CoexpressionAtlas	FacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_1000	SLK STARD8 ZNF280D CCDC186 NASP PREX2 CRYM USP38 BRCA2 GCC2 MCM3AP DIAPH1 MMS19 CEP295 RPGR TAF1 LMNTD1	4.56e-06	989	102	17	Facebase_RNAseq_e10.5_Maxillary Arch_1000
CoexpressionAtlas	DevelopingGonad_P2_epididymis_emap-30199_k-means-cluster#2_top-relative-expression-ranked_200	LUC7L2 NISCH NRK	3.77e-05	14	102	3	gudmap_developingGonad_P2_epididymis_200_k2
ToppCell	facs-Kidney-nan-3m\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH6 STARD8 DDB1 ALB RESP18 KNG1	4.66e-06	182	105	6	4c5d14e33ebdf117b5aa9e2f57aaa89aa51f72bf
ToppCell	droplet-Marrow-nan-3m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYCBP2 SPTBN1 RSF1 ANKLE2 GCC2 DIAPH1	5.12e-06	185	105	6	7adfa929930cfa795cbfbd9f1a0b439e08aa765d
ToppCell	Bronchial-NucSeq-Endothelial-Endothelia_vascular-VE_systemic_venous\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	STARD8 PREX2 AFAP1L2 GNA14 UPP1 RPGR	6.92e-06	195	105	6	fde8e7b38b3631109b95ef111c5f6e3f9878cfbd
ToppCell	H1299-infected-SARSCoV2\|infected / Cell line, Condition and Strain	KDM5A RSF1 NEFH NISCH CEP295 KNG1	7.33e-06	197	105	6	0fa3e4cf93e77d78b1f97b906c5b13ca741ae17e
ToppCell	LPS-antiTNF-Unknown-Endothelial-Monocytes-Macrophages\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SFMBT1 ZNF280D GBP3 FANCM ACSL1	2.19e-05	142	105	5	b66f9602dba30d1d4fbcc49ceb112eb5bd916ba1
ToppCell	droplet-Liver-HEPATOCYTES-1m-Epithelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPD1 ETNPPL ACSL1 ALB KNG1	3.65e-05	158	105	5	9f58428f70d1427b20122c5c1cc7bf521d0f4832
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	STARD8 SPTBN1 PREX2 NHSL1 GNA14	5.02e-05	169	105	5	987ff79ad563825dd9877ea8ccb536758f8c6700
ToppCell	facs-Limb_Muscle-Muscle_Diaphragm-18m-Endothelial-new-cluster\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPD1 NEFH GNA14 ALB KNG1	5.46e-05	172	105	5	2fcc6278ead890019a6505fb4fcb518751262dda
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SPTBN1 PSMB10 PREX2 NHSL1 RPGR	6.09e-05	176	105	5	64e426f5e84884ce2c29acf6f4b958962a63927f
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_A_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CCDC186 VWDE ITPR1 GCC2 RESP18	6.26e-05	177	105	5	1dc69c661e70e7e22bd9d7cf953eb638da9fd43c
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_A_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CCDC186 VWDE ITPR1 GCC2 RESP18	6.26e-05	177	105	5	426a9845df7fd13b02e744532c336c60bc4d4a22
ToppCell	normal-na-Lymphocytic_T-CD4-positive,_alpha-beta_T_cell-male\|normal / PBMC cell types (v2) per disease, treatment status, and sex	FBLL1 SPTBN1 GNA14 GCC2 CCSER2	6.43e-05	178	105	5	fa3585383a1e7da460c88a802aaa81246d681b6b
ToppCell	droplet-Marrow-nan-3m-Hematologic-nan\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYCBP2 SPTBN1 GCC2 DIAPH1 SENP6	7.14e-05	182	105	5	e78ba2c5cae480c16a596ce7c3bf2d480becacf4
ToppCell	droplet-Marrow-nan-3m-Hematologic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYCBP2 SPTBN1 GCC2 DIAPH1 SENP6	7.14e-05	182	105	5	1710eab3037a87609d21838be2d2d29c3bc36651
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	LRRK1 RGS4 CRYM GNA14 GCC2	7.14e-05	182	105	5	fa16e194f04250149c82e86551270b244cbc8af4
ToppCell	wk_15-18-Epithelial-Proximal_epithelial-GHRL+_neuroendocrine\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	MYH6 FBLL1 RGS4 ACSL1 CRYM	7.32e-05	183	105	5	8820cfed27b292bc0bc9cde4005219ed41900552
ToppCell	droplet-Marrow-nan-3m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYCBP2 SPTBN1 RSF1 GCC2 DIAPH1	7.51e-05	184	105	5	1154a5ad7b8512272b7476f949ddac350910bfb7
ToppCell	facs-Pancreas-Endocrine-3m-Epithelial-pancreatic_A_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWDE RGS4 ITPR1 UPP1 RESP18	7.91e-05	186	105	5	4bb54043f944a979db91bde9a86dd66f498c7658
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SPTBN1 NASP PREX2 GNA14 STARD9	8.11e-05	187	105	5	35c382c0aabd46906113e5db30ea24bb8e658899
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CCDC186 SPTBN1 DIAPH1 SENP6 ARHGAP20	8.96e-05	191	105	5	60c986d2dcbc19d9338c03da6cb5e1d92fd48f8e
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	SFMBT1 PREPL SIRPG GCC2 CCSER2	8.96e-05	191	105	5	d9a6f61fcda4f5352488f7f55cb9b57aeacc717f
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CCDC186 SPTBN1 DIAPH1 SENP6 ARHGAP20	8.96e-05	191	105	5	09db184cb90fe282a14474d7217068c58092c6f8
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CCDC186 SPTBN1 DIAPH1 SENP6 ARHGAP20	8.96e-05	191	105	5	973117730d6ba5f127e7a0bfabfd0ff2ca7ac131
ToppCell	droplet-Heart\|droplet / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH6 STARD8 SPTBN1 PSMB10 CCSER2	9.18e-05	192	105	5	67a7e07a11091120edbccf739836235c422ec9c6
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	SFMBT1 HIVEP2 SPTBN1 SIRPG GCC2	9.18e-05	192	105	5	7ab626a516b07d899175ff12f1c8257688324e4b
ToppCell	Smart-seq2-thymus_(Smart-seq2)-myeloid-myeloid_monocytic\|thymus_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	NUP214 ACSL1 DIAPH1 UPP1 NUP93	9.87e-05	195	105	5	ae98215b7b7f22f1aca690920ce6092dc4a3c7db
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_adventitial_fibro_(9)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	SPTBN1 PREX2 GNA14 SBF2 ARHGAP20	9.87e-05	195	105	5	70387a62f121f8c374dba1aca9ab65cfed6a0b10
ToppCell	Smart-seq2-thymus_(Smart-seq2)-myeloid-myeloid_monocytic-monocyte\|thymus_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	NUP214 ACSL1 DIAPH1 UPP1 NUP93	9.87e-05	195	105	5	6fcab7aa4db958ccad0300adea9aaae52ace5bff
ToppCell	Adult-Immune-alveolar_macrophage_(MARCO_positive)\|Adult / Lineage, Cell type, age group and donor	ABCC3 PTAFR ACSL1 SBF2 UPP1	9.87e-05	195	105	5	55e25f702af19146a161861cfd15f40bbda1dc35
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYCBP2 DDB1 KMT2C NISCH RESP18	9.87e-05	195	105	5	7796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell	Posterior_cortex-Hematopoietic-MACROPHAGE\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	ABCC3 PTAFR ITGAE CD200R1	9.98e-05	102	105	4	57ad3d48adeb41f6ab65883e61d3b1e74a94ad1a
ToppCell	Posterior_cortex-Hematopoietic-MACROPHAGE-MP1(C1qb)-MACROPHAGE_Macrophage.C1qb.Mrc1_(Resident_macrophage)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	ABCC3 PTAFR ITGAE CD200R1	9.98e-05	102	105	4	0ec549ee94da5f2d7275490e90d816c645f6d4fc
ToppCell	Posterior_cortex-Hematopoietic-MACROPHAGE-MP1(C1qb)-MACROPHAGE_Macrophage.C1qb.Mrc1_(Resident_macrophage)--\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	ABCC3 PTAFR ITGAE CD200R1	9.98e-05	102	105	4	30fa92383898f370dabc41dd23d6907f14ba1a06
ToppCell	Posterior_cortex-Hematopoietic-MACROPHAGE-MP1(C1qb)-MACROPHAGE_Macrophage.C1qb.Mrc1_(Resident_macrophage)-\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	ABCC3 PTAFR ITGAE CD200R1	9.98e-05	102	105	4	c58e09aaa11b664c7d99e91f903561fa18460f05
ToppCell	Posterior_cortex-Hematopoietic-MACROPHAGE-MP1(C1qb)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	ABCC3 PTAFR ITGAE CD200R1	9.98e-05	102	105	4	9392288e284b71f3a208d9f283e6e3c944b7dd10
ToppCell	severe-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	FRAS1 BTAF1 KMT2C GCC2 SNRNP200	1.04e-04	197	105	5	57ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCell	mild-dn_T\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	HIVEP2 SPTBN1 DBT SIRPG CCSER2	1.04e-04	197	105	5	07a1f59c83b748825e0708cd1cc7b63a2cb856cc
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	ABCC3 FRAS1 SPTBN1 SBF2 ARHGAP20	1.04e-04	197	105	5	0034bae02ee7fcfea520d453ca3c842ab6963b12
ToppCell	10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_capilar-G\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CCDC186 SPTBN1 PREX2 RPGR PINK1	1.06e-04	198	105	5	0a4626b51ba8b52acbaf616f0ced850079cd7149
ToppCell	LPS_anti-TNF-Hematopoietic_Myeloid-Dendritic_cells\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	GPD1 MYH7 CD200R1 NEFH WDR1	1.06e-04	198	105	5	b2c8d5956f8449df4b69fb1b30632253440f815e
Disease	autosomal dominant hyaline body myopathy (implicated_via_orthology)	MYH6 MYH7 MYH13	5.16e-06	10	105	3	DOID:0111269 (implicated_via_orthology)
Disease	distal arthrogryposis type 2B3 (implicated_via_orthology)	MYH6 MYH7 MYH13	5.16e-06	10	105	3	DOID:0111602 (implicated_via_orthology)
Disease	distal arthrogryposis type 1 (implicated_via_orthology)	MYH6 MYH7 MYH13	5.16e-06	10	105	3	DOID:0111596 (implicated_via_orthology)
Disease	dilated cardiomyopathy 1S (implicated_via_orthology)	MYH6 MYH7 MYH13	5.16e-06	10	105	3	DOID:0110454 (implicated_via_orthology)
Disease	congenital myopathy 6 (implicated_via_orthology)	MYH6 MYH7 MYH13	5.16e-06	10	105	3	DOID:0080719 (implicated_via_orthology)
Disease	inclusion body myositis (implicated_via_orthology)	MYH6 MYH7 MYH13	5.16e-06	10	105	3	DOID:3429 (implicated_via_orthology)
Disease	distal arthrogryposis type 2A (implicated_via_orthology)	MYH6 MYH7 MYH13	5.16e-06	10	105	3	DOID:0111605 (implicated_via_orthology)
Disease	familial hypertrophic cardiomyopathy (implicated_via_orthology)	MYH6 MYH7 MYH13	5.16e-06	10	105	3	DOID:0080326 (implicated_via_orthology)
Disease	distal myopathy (implicated_via_orthology)	MYH6 MYH7 MYH13	9.41e-06	12	105	3	DOID:11720 (implicated_via_orthology)
Disease	myotonia congenita (implicated_via_orthology)	MYH6 MYH7 MYH13	9.41e-06	12	105	3	DOID:2106 (implicated_via_orthology)
Disease	restrictive cardiomyopathy (implicated_via_orthology)	MYH6 MYH7 MYH13	1.22e-05	13	105	3	DOID:397 (implicated_via_orthology)
Disease	distal arthrogryposis (implicated_via_orthology)	MYH6 MYH7 MYH13	1.93e-05	15	105	3	DOID:0050646 (implicated_via_orthology)
Disease	Cardiomyopathy, Familial Hypertrophic, 1 (disorder)	MYH6 MYH7	7.49e-05	4	105	2	C3495498
Disease	Hypertrophic cardiomyopathy 1	MYH6 MYH7	7.49e-05	4	105	2	cv:C3495498
Disease	Caveolinopathy	MYH6 MYH7	7.49e-05	4	105	2	cv:C5679790
Disease	CARDIOMYOPATHY, FAMILIAL HYPERTROPHIC, 1	MYH6 MYH7	7.49e-05	4	105	2	192600
Disease	Klatskin's tumor (is_implicated_in)	PREX2 KMT2C	1.25e-04	5	105	2	DOID:4927 (is_implicated_in)
Disease	hypothyroidism (biomarker_via_orthology)	MYH6 MYH7 L1CAM NEFH	1.95e-04	80	105	4	DOID:1459 (biomarker_via_orthology)
Disease	Idiopathic hypertrophic subaortic stenosis	MYH6 MYH7	2.60e-04	7	105	2	C0700053
Disease	Obstructive asymmetric septal hypertrophy	MYH6 MYH7	2.60e-04	7	105	2	C0597124
Disease	Kartagener Syndrome	DNAAF5 RPGR CCDC40	2.64e-04	35	105	3	C0022521
Disease	Ciliary Dyskinesia, Primary, 1, With Or Without Situs Inversus	DNAAF5 RPGR CCDC40	2.64e-04	35	105	3	C4551906
Disease	Polynesian Bronchiectasis	DNAAF5 RPGR CCDC40	2.64e-04	35	105	3	C4317124
Disease	Cardiomyopathy, Hypertrophic, Familial	MYH6 MYH7	4.44e-04	9	105	2	C0949658
Disease	Liver Cirrhosis, Experimental	GLT8D1 PSMB10 PSTPIP1 PTAFR CD200R1 FABP7 ACSL1 GNA14 ALB KNG1	4.46e-04	774	105	10	C0023893
Disease	heart disease (is_marker_for)	MYH7 ALB	5.54e-04	10	105	2	DOID:114 (is_marker_for)
Disease	Muscular dystrophy, limb-girdle, autosomal dominant	MYH6 MYH7	5.54e-04	10	105	2	cv:C5675009
Disease	Drug-Induced Liver Disease	GPD1 DBT DDB1 ITPR1 ACSL1 ALB KNG1	6.17e-04	404	105	7	C0860207
Disease	Drug-Induced Acute Liver Injury	GPD1 DBT DDB1 ITPR1 ACSL1 ALB KNG1	6.17e-04	404	105	7	C3658290
Disease	Hepatitis, Toxic	GPD1 DBT DDB1 ITPR1 ACSL1 ALB KNG1	6.17e-04	404	105	7	C0019193
Disease	Chemically-Induced Liver Toxicity	GPD1 DBT DDB1 ITPR1 ACSL1 ALB KNG1	6.17e-04	404	105	7	C4279912
Disease	Chemical and Drug Induced Liver Injury	GPD1 DBT DDB1 ITPR1 ACSL1 ALB KNG1	6.17e-04	404	105	7	C4277682
Disease	Hepatitis, Drug-Induced	GPD1 DBT DDB1 ITPR1 ACSL1 ALB KNG1	6.17e-04	404	105	7	C1262760
Disease	Primary Ciliary Dyskinesia	DNAAF5 RPGR CCDC40	6.34e-04	47	105	3	C4551720
Disease	myopathy (implicated_via_orthology)	MYH6 MYH7 MYH13	6.74e-04	48	105	3	DOID:423 (implicated_via_orthology)
Disease	Hypotension	NISCH ALB KNG1	9.01e-04	53	105	3	C0020649
Disease	Intellectual Disability	HIVEP2 KDM5A PREPL KMT2C DIAPH1 TAF1 RAI1	1.11e-03	447	105	7	C3714756
Disease	Bone marrow hypocellularity	FANCM BRCA2	1.85e-03	18	105	2	C1855710
Disease	cardiomyopathy (implicated_via_orthology)	MYH6 MYH7 MYH13	2.10e-03	71	105	3	DOID:0050700 (implicated_via_orthology)
Disease	Paroxysmal atrial fibrillation	MYH6 MYH7 SUN1 WDR1	2.38e-03	156	105	4	C0235480
Disease	familial atrial fibrillation	MYH6 MYH7 SUN1 WDR1	2.38e-03	156	105	4	C3468561
Disease	Persistent atrial fibrillation	MYH6 MYH7 SUN1 WDR1	2.38e-03	156	105	4	C2585653
Disease	intellectual disability (implicated_via_orthology)	HIVEP2 ZNF280D KDM5A	2.45e-03	75	105	3	DOID:1059 (implicated_via_orthology)
Disease	Arthrogryposis	L1CAM SMN1	2.52e-03	21	105	2	C0003886
Disease	Atrial Fibrillation	MYH6 MYH7 SUN1 WDR1	2.60e-03	160	105	4	C0004238
Disease	cholangiocarcinoma (is_implicated_in)	PREX2 ALB	2.77e-03	22	105	2	DOID:4947 (is_implicated_in)
Disease	Primary familial hypertrophic cardiomyopathy	MYH6 MYH7	2.77e-03	22	105	2	cv:C0949658
Disease	epilepsy (implicated_via_orthology)	L1CAM RGS4 SLC12A4 SBF2	2.78e-03	163	105	4	DOID:1826 (implicated_via_orthology)
Disease	electrocardiography	SFMBT1 EPS15 MYH6 SLK MYCBP2 GRK7 SPTBN1	2.91e-03	530	105	7	EFO_0004327
Disease	creatinine measurement	SFMBT1 GRK7 NASP ETNPPL BTAF1 CD200R1 TMEM131L WDR1 KNG1 TDRD12	2.91e-03	995	105	10	EFO_0004518
Disease	dilated cardiomyopathy (implicated_via_orthology)	MYH6 MYH7 MYH13	2.95e-03	80	105	3	DOID:12930 (implicated_via_orthology)
Disease	lung non-small cell carcinoma (is_marker_for)	KDM5A L1CAM PREX2 ALB	3.17e-03	169	105	4	DOID:3908 (is_marker_for)
Disease	stomach carcinoma (is_marker_for)	KDM5A KMT2C	3.29e-03	24	105	2	DOID:5517 (is_marker_for)

Protein segments in the cluster

Peptide	Gene	Start	Entry
ESITVSDKENETCLA	ZNF280D	801	Q6N043
CRQTEVKALSTQVEE	CCDC186	661	Q7Z3E2
CLSESETVNKERANS	ANKLE2	286	Q86XL3
TEFAKTCVADESAEN	ALB	71	P02768
CVSVKDDSILSVTVD	CPSF3	626	Q9UKF6
DTACTIAATASVVKE	BSDC1	46	Q9NW68
RNIVSDCSAFVKATE	ACSL1	291	P33121
DADRVSCIVSAAKNS	AFAP1L2	461	Q8N4X5
EIVSVTAACEELRKS	DIAPH1	956	O60610
VACVVTTKEIAEAFS	ETNPPL	286	Q8TBG4
SVTREITDNRACAKE	CFAP206	111	Q8IYR0
KFADTVQGEVRVCSS	CRYM	176	Q14894
RCDVTDNQSEVADKT	NUP93	396	Q8N1F7
VEKRDAFTTICTVVN	RAI1	1601	Q7Z5J4
LCAIETSAKDSSNVE	RAB43	156	Q86YS6
EIISDTKVDANQRSC	ABCC3	1171	O15438
EEAVEAVNAKCSSLE	MYH7	1401	P12883
DSICEVQSDKASVTI	DBT	96	P11182
KARQCKDSATEAERV	PSTPIP1	176	O43586
FDEREDTKSCTIVIN	FRAS1	2616	Q86XX4
VNVDKAVVSGSTERC	KMT2C	271	Q8NEZ4
SVESCIRVLSDVAKS	ITPR1	1541	Q14643
RFIDKVCTESGVTQD	SBF2	821	Q86WG5
DAAVVAKDTVVCTFE	LRRK1	1961	Q38SD2
KEDSQSCRVAALEAS	MMS19	496	Q96T76
SETEAKINTVCSADF	LRRC53	756	A6NM62
NDKRTSDTDEIAATC	FANCM	896	Q8IYD8
RETCSQELKNAVETD	MCM3AP	1186	O60318
SCVIASDKENVTVAA	ITGAE	1056	P38570
SETRDSSCQTEDVKV	NHSL1	261	Q5SYE7
IKANCIDSTASAEAV	FBLL1	276	A6NHQ2
IEEKQAESRRAVSAC	PINK1	111	Q9BXM7
FQSEESKARACSETE	MLH3	1021	Q9UHC1
TEDIQAACTKDLTTV	MLH3	1071	Q9UHC1
QLEESEFTCAAAVKA	MYO18A	1691	Q92614
SEDARTSCKDDEAVV	NUP214	996	P35658
CVASTELDVVESRAQ	L1CAM	591	P32004
KLDADVEFNRCSVVS	LMNTD1	261	Q8N9Z9
ETNETKETNCTDERI	CD200R1	91	Q8TD46
EIEVECVKAESAQAS	GBP3	486	Q9H0R5
FSEDCDSASTKVVIR	GLT8D1	196	Q68CQ7
VSKVEAACDSLVDTV	PLA2G12B	151	Q9BX93
DQCVEIRSAKDDFTS	NBAS	106	A2RRP1
DAVKEAETCASVAQL	KDM5A	786	P29375
EEKSVSGTDVQEECR	NASP	241	P49321
QAETRDALKCDVTSA	NEFH	256	P12036
VNRDQCFTSEVVSKA	RESP18	161	Q5W5W9
TCVEEDATVLAKDRA	CCSER2	346	Q9H7U1
IKEQESSQASTEECE	BRCA2	3391	P51587
AKSRAKCDVDETVSS	BTAF1	1536	O14981
KAVSEACTEIDAISV	CCDC40	476	Q4G0X9
CRAAKAEQATVTSEF	GCC2	1306	Q8IWJ2
NVVCEKAATSVDAFR	GFOD2	91	Q3B7J2
NIASEVADEKFCETT	GPD1	151	P21695
FVARETTCSKESNEE	KNG1	321	P01042
EVTTAVTEKVCSELD	EPS15	576	P42566
ASAVDAATEQKTCDS	CCDC12	151	Q8WUD4
DEEAAVVQSCTRSAE	DNAAF5	411	Q86Y56
FDETTADDRNCKSVV	FABP7	71	O15540
ATKCQAATTEEERVA	GRK7	131	Q8WTQ7
VDESERFQECISIKS	CEP295	1211	Q9C0D2
ELEKRVSSEQVCSSS	CEP295	1536	Q9C0D2
LASEKEVVECQSTST	RSF1	641	Q96T23
VCQKDSAATTDEERQ	DDB1	976	Q16531
QSFIADCDRRTEVAK	LUC7L2	91	Q9Y383
FDESTAIKVCIDQSA	NRK	1346	Q7Z2Y5
SCKQDVIFDSERESV	RPGR	696	Q92834
CLSAEEKESQRISAE	GNA14	6	O95837
EVSVRCDTRENASDI	ARHGAP20	561	Q9P2F6
RIDSKDVFCAIQVDS	SYDE2	696	Q5VT97
TVVITEQAVDTCFKA	UPP1	151	Q16831
NACILESVSEKTERS	SLK	356	Q9H2G2
QESTREVCKADAEIA	TMEM131L	1261	A2VDJ0
VQATKEVNLDSCTRE	RGS4	121	P49798
KCSRATTDTVTEVVV	PTAFR	316	P25105
EVECSVESEVSQKSL	TAF1L	296	Q8IZX4
QEVECSVESEVSQKS	TAF1	276	P21675
ATTQVEARLCAVEED	TDRD12	166	Q587J7
AETEIVCKVVESSSI	TDRD12	686	Q587J7
DTSGESDVRCVNEVI	PRDM11	156	Q9NQV5
ATIASIDFKRETCVV	SMN1	111	Q16637
EEDKNCSRALSVVST	MYCBP2	1901	O75592
VCDASKVVTVFSVAD	WDR1	506	O75083
DTRATNDSVVADKSC	PSMB10	56	P40306
KVERSQSCSDTAQER	RNF169	286	Q8NCN4
EEKTDCQESSKEAVR	STARD9	1696	Q9P2P6
DAEEAVEAVNAKCSS	MYH6	1401	P13533
VCQRETASTLTENKD	SIRPG	291	Q9P1W8
SVEIATVEVKCQAEA	STARD8	346	Q92502
SRDQFDICAKTAVVD	SLC12A4	316	Q9UP95
DICAKTAVVDNETVA	SLC12A4	321	Q9UP95
IKAEIDARNDSFTTC	SPTBN1	1956	Q01082
CDAETRVTIEVTVKS	VWDE	1166	Q8N2E2
VQEDTIKVAVDRSCD	TTLL8	561	A6PVC2
RDVVEVTISESQEKC	ZNF408	671	Q9H9D4
RASEVCLDDTVTTEK	NISCH	431	Q9Y2I1
RTCRTVEDQFSEIKA	MYH13	1251	Q9UKX3
AVIQKCSTVEDSCIS	SENP6	791	Q9GZR1
AAKIRTEDSEASTCV	PREPL	171	Q4J6C6
CAASKVDKNVTEETV	PREX2	56	Q70Z35
ECSETSLQEVASKAA	USP38	556	Q8NB14
SASTEVLRTEAEQCK	SNRNP200	756	O75643
SESVRDVVCDNCTKI	USP30	276	Q70CQ3
TVEIVKTADRVTEFC	SFMBT1	586	Q9UHJ3
KTGCETVDAVQERVD	SUN1	496	O94901
RSESAELVACTQDKA	HIVEP2	816	P31629
QDASSQVKREDTLCV	ZNF282	286	Q9UDV7
KTDSTIRTENEQACE	ZNF7	81	P17097
ETAASKAREECARQQ	TTLL13	501	A6NNM8