Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	acetylcholine receptor regulator activity	SPDYE1 SPDYE2 SPDYE5 SPDYE16	6.26e-06	27	90	4	GO:0030548
GeneOntologyMolecularFunction	neurotransmitter receptor regulator activity	SPDYE1 SPDYE2 SPDYE5 SPDYE16	7.27e-06	28	90	4	GO:0099602
GeneOntologyMolecularFunction	N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity	CHSY1 CHSY3	1.20e-04	4	90	2	GO:0050510
GeneOntologyMolecularFunction	glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity	CHSY1 CHSY3	2.98e-04	6	90	2	GO:0047238
GeneOntologyMolecularFunction	acetylgalactosaminyltransferase activity	CHSY1 CHSY3 GALNT5	5.22e-04	35	90	3	GO:0008376
GeneOntologyMolecularFunction	glucuronosyltransferase activity	CHSY1 CHSY3 UGT2B28	5.22e-04	35	90	3	GO:0015020
GeneOntologyMolecularFunction	RNA polymerase II activity	POLR2J3 POLR2J2	1.08e-03	11	90	2	GO:0001055
GeneOntologyBiologicalProcess	positive regulation of cyclin-dependent protein serine/threonine kinase activity	SPDYE1 SPDYE2 SPDYE5 SPDYE16	3.82e-06	25	89	4	GO:0045737
GeneOntologyBiologicalProcess	positive regulation of cyclin-dependent protein kinase activity	SPDYE1 SPDYE2 SPDYE5 SPDYE16	6.13e-06	28	89	4	GO:1904031
GeneOntologyBiologicalProcess	visceral motor neuron differentiation	ISL2 ISL1	5.51e-05	3	89	2	GO:0021524
Domain	Spy1	SPDYE1 SPDYE2 SPDYE21 SPDYE5 SPDYE16	9.35e-10	11	88	5	PF11357
Domain	Speedy	SPDYE1 SPDYE2 SPDYE21 SPDYE5 SPDYE16	9.35e-10	11	88	5	IPR020984
Domain	RNA_pol_Rpb11_13-16kDa_CS	POLR2J3 POLR2J2	1.31e-04	4	88	2	IPR008193
Domain	RNA_POL_L_13KD	POLR2J3 POLR2J2	1.31e-04	4	88	2	PS01154
Domain	RBP11-like_dimer	POLR2J3 POLR2J2	3.25e-04	6	88	2	IPR009025
Domain	RNA_pol_L	POLR2J3 POLR2J2	3.25e-04	6	88	2	PF01193
Domain	Chond_GalNAc	CHSY1 CHSY3	6.03e-04	8	88	2	IPR008428
Domain	CHGN	CHSY1 CHSY3	6.03e-04	8	88	2	PF05679
Domain	CA	FREM2 DSG2 PCDH11Y PCDH12	2.14e-03	115	88	4	SM00112
Domain	Cadherin	FREM2 DSG2 PCDH11Y PCDH12	2.35e-03	118	88	4	IPR002126
Domain	-	INTS9 DCLRE1B	3.95e-03	20	88	2	3.60.15.10
Domain	Metallo-B-lactamas	INTS9 DCLRE1B	3.95e-03	20	88	2	IPR001279
Domain	-	TELO2 TERB1 PDS5A ECPAS TRRAP	4.00e-03	222	88	5	1.25.10.10
Domain	LIM	PRICKLE2 ISL2 ISL1	4.23e-03	69	88	3	PF00412
Domain	-	PRICKLE2 ISL2 ISL1	4.41e-03	70	88	3	2.10.110.10
Domain	Znf_LIM	PRICKLE2 ISL2 ISL1	4.59e-03	71	88	3	IPR001781
Domain	LIM_DOMAIN_1	PRICKLE2 ISL2 ISL1	4.59e-03	71	88	3	PS00478
Domain	LIM_DOMAIN_2	PRICKLE2 ISL2 ISL1	4.59e-03	71	88	3	PS50023
Domain	LIM	PRICKLE2 ISL2 ISL1	4.59e-03	71	88	3	SM00132
Domain	Actinin_actin-bd_CS	SYNE2 DMD	5.21e-03	23	88	2	IPR001589
Domain	Spectrin	SYNE2 DMD	5.21e-03	23	88	2	PF00435
Domain	ACTININ_2	SYNE2 DMD	5.21e-03	23	88	2	PS00020
Domain	ACTININ_1	SYNE2 DMD	5.21e-03	23	88	2	PS00019
Domain	ARM-type_fold	TELO2 TERB1 PDS5A CTIF ECPAS TRRAP	5.33e-03	339	88	6	IPR016024
Pubmed	Murine fertility and spermatogenesis are independent of the testis-specific Spdye4a gene.	SPDYE1 SPDYE2 SPDYE5 SPDYE16	5.47e-09	9	91	4	36272447
Pubmed	Identification and comparative analysis of multiple mammalian Speedy/Ringo proteins.	SPDYE1 SPDYE2 SPDYE5 SPDYE16	3.08e-08	13	91	4	15611625
Pubmed	Characterization of a new family of cyclin-dependent kinase activators.	SPDYE1 SPDYE2 SPDYE5 SPDYE16	1.02e-07	17	91	4	15574121
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	PIK3AP1 TTF2 ABL2 RAPH1 DSG2 PHF12 SSX2IP TNRC6A CTIF RASSF8 ECPAS DDX41	2.35e-06	853	91	12	28718761
Pubmed	Distinct regions of RPB11 are required for heterodimerization with RPB3 in human and yeast RNA polymerase II.	POLR2J3 POLR2J2	6.77e-06	2	91	2	15987790
Pubmed	Chondroitin sulfate synthase-3. Molecular cloning and characterization.	CHSY1 CHSY3	6.77e-06	2	91	2	12907687
Pubmed	Necroptosis mediates myofibre death in dystrophin-deficient mice.	RIPK3 DMD	6.77e-06	2	91	2	30194302
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	FSIP2 PLK2 UBAP2 ABL2 RAPH1 DSG2 SYNE2 SSX2IP RASSF8 ARHGEF17 DDX41	1.57e-05	861	91	11	36931259
Pubmed	Glycine release from radial cells modulates the spontaneous activity and its propagation during early spinal cord development.	ISL2 ISL1	2.03e-05	3	91	2	20053920
Pubmed	Wnt-promoted Isl1 expression through a novel TCF/LEF1 binding site and H3K9 acetylation in early stages of cardiomyocyte differentiation of P19CL6 cells.	ISL1 LEF1	2.03e-05	3	91	2	24610003
Pubmed	Differential Islet-1 expression among lumbosacral spinal motor neurons in prenatal mouse.	ISL2 ISL1	2.03e-05	3	91	2	19236857
Pubmed	Chondroitin synthase-3 regulates nucleus pulposus degeneration through actin-induced YAP signaling.	CHSY1 CHSY3	2.03e-05	3	91	2	33089528
Pubmed	Human PMS2 gene family: origin, molecular evolution, and biological implications.	POLR2J3 POLR2J2	2.03e-05	3	91	2	16913423
Pubmed	DNA cross-link repair protein SNM1A interacts with PIAS1 in nuclear focus formation.	DCLRE1B PIAS1	2.03e-05	3	91	2	15572677
Pubmed	Initial trajectories of sensory axons toward laminar targets in the developing mouse spinal cord.	ISL2 ISL1	2.03e-05	3	91	2	9100133
Pubmed	ECEL1 mutation implicates impaired axonal arborization of motor nerves in the pathogenesis of distal arthrogryposis.	ISL2 ISL1	2.03e-05	3	91	2	26951213
Pubmed	Islet-1 expression in thoracic spinal motor neurons in prenatal mouse.	ISL2 ISL1	2.03e-05	3	91	2	21651972
Pubmed	Expression of sorting nexin 18 (SNX18) is dynamically regulated in developing spinal motor neurons.	ISL2 ISL1	2.03e-05	3	91	2	21339182
Pubmed	Ago2/miRISC-mediated inhibition of CBP80/20-dependent translation and thereby abrogation of nonsense-mediated mRNA decay require the cap-associating activity of Ago2.	TNRC6A CTIF	2.03e-05	3	91	2	21840310
Pubmed	Emergence of sigh rhythmogenesis in the embryonic mouse.	ISL2 ISL1	2.03e-05	3	91	2	24591570
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	FREM2 ADRA1A RPS10 PRICKLE2 CPSF1 PDS5A ECPAS CFAP44 ARHGEF17 SPDYE16	2.33e-05	736	91	10	29676528
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	FSIP2 PHC3 CENPC BAZ1A PHF12 PDS5A DDX41 TRRAP PIAS1	3.15e-05	608	91	9	36089195
Pubmed	A human RNA polymerase II subunit is encoded by a recently generated multigene family.	POLR2J3 POLR2J2	4.05e-05	4	91	2	11747469
Pubmed	Generation and characterization of Rgs4 mutant mice.	ISL2 ISL1	4.05e-05	4	91	2	15870291
Pubmed	Robo1 and 2 Repellent Receptors Cooperate to Guide Facial Neuron Cell Migration and Axon Projections in the Embryonic Mouse Hindbrain.	ISL2 ISL1	4.05e-05	4	91	2	30685539
Pubmed	Necdin plays a role in the serotonergic modulation of the mouse respiratory network: implication for Prader-Willi syndrome.	ISL2 ISL1	4.05e-05	4	91	2	18272695
Pubmed	An oncogenic viral interferon regulatory factor upregulates CUB domain-containing protein 1 to promote angiogenesis by hijacking transcription factor lymphoid enhancer-binding factor 1 and metastasis suppressor CD82.	CDCP1 LEF1	4.05e-05	4	91	2	32555380
Pubmed	[New genes on human chromosome 7: bioinformatic analysis of a gene cluster from the POLR2J family].	POLR2J3 POLR2J2	4.05e-05	4	91	2	15586814
Pubmed	KPC2 relocalizes HOXA2 to the cytoplasm and decreases its transcriptional activity.	ISL2 ISL1	4.05e-05	4	91	2	26303204
Pubmed	A stromal progenitor and ILC2 niche promotes muscle eosinophilia and fibrosis-associated gene expression.	DMD IL5	4.05e-05	4	91	2	33852849
Pubmed	Structural basis for partial redundancy in a class of transcription factors, the LIM homeodomain proteins, in neural cell type specification.	ISL2 ISL1	4.05e-05	4	91	2	22025611
Pubmed	A new role for angiogenin in neurite growth and pathfinding: implications for amyotrophic lateral sclerosis.	ISL2 ISL1	4.05e-05	4	91	2	17468498
Pubmed	Increased apoptosis of motoneurons and altered somatotopic maps in the brachial spinal cord of Hoxc-8-deficient mice.	ISL2 ISL1	4.05e-05	4	91	2	9486801
Pubmed	Chondroitin synthases I, II, III and chondroitin sulfate glucuronyltransferase expression in colorectal cancer.	CHSY1 CHSY3	4.05e-05	4	91	2	21468578
Pubmed	Prenatal methamphetamine exposure causes dysfunction in glucose metabolism and low birthweight.	ISL2 ISL1	4.05e-05	4	91	2	36353228
Pubmed	Identification of STAM1 as a novel effector of ventral projection of spinal motor neurons.	ISL2 ISL1	4.05e-05	4	91	2	27161150
Pubmed	The COPII cargo adapter SEC24C is essential for neuronal homeostasis.	ISL2 ISL1 EDEM1	4.31e-05	26	91	3	29939162
Pubmed	Distinct adhesion-independent functions of β-catenin control stage-specific sensory neurogenesis and proliferation.	ISL2 ISL1 LEF1	4.84e-05	27	91	3	25885041
Pubmed	Reconstruction of phrenic neuron identity in embryonic stem cell-derived motor neurons.	PCDH11Y ISL2 ISL1	4.84e-05	27	91	3	24496616
Pubmed	Retinal axon misrouting at the optic chiasm in mice with neural tube closure defects.	ISL2 ISL1	6.74e-05	5	91	2	10862153
Pubmed	Sonic hedgehog regulates the position of the trigeminal ganglia.	ISL2 ISL1	6.74e-05	5	91	2	14499653
Pubmed	Forced expression of Phox2 homeodomain transcription factors induces a branchio-visceromotor axonal phenotype.	ISL2 ISL1	6.74e-05	5	91	2	17208219
Pubmed	Distinct timing of neurogenesis of ipsilateral and contralateral retinal ganglion cells.	ISL2 ISL1	6.74e-05	5	91	2	29761490
Pubmed	c-Abl, Lamellipodin, and Ena/VASP proteins cooperate in dorsal ruffling of fibroblasts and axonal morphogenesis.	ABL2 RAPH1	6.74e-05	5	91	2	20417104
Pubmed	Expression patterns of Hox10 paralogous genes during lumbar spinal cord development.	ISL2 ISL1	6.74e-05	5	91	2	16495162
Pubmed	The thymocyte-specific MAR binding protein, SATB1, interacts in vitro with a novel variant of DNA-directed RNA polymerase II, subunit 11.	POLR2J3 POLR2J2	6.74e-05	5	91	2	12036295
Pubmed	Strain-dependent embryonic lethality in mice lacking the retinoblastoma-related p130 gene.	ISL2 ISL1	6.74e-05	5	91	2	9806916
Pubmed	The pathological consequences of impaired genome integrity in humans; disorders of the DNA replication machinery.	MCM9 CDC7	6.74e-05	5	91	2	27757957
Pubmed	Targeting of the EphA4 tyrosine kinase receptor affects dorsal/ventral pathfinding of limb motor axons.	ISL2 ISL1	6.74e-05	5	91	2	10887087
Pubmed	Genetics of mirror movements identifies a multifunctional complex required for Netrin-1 guidance and lateralization of motor control.	ISL2 ISL1	6.74e-05	5	91	2	37172092
Pubmed	Delayed neurogenesis leads to altered specification of ventrotemporal retinal ganglion cells in albino mice.	ISL2 ISL1	6.74e-05	5	91	2	24885435
Pubmed	Independent requirement for ISL1 in formation of pancreatic mesenchyme and islet cells.	ISL2 ISL1	6.74e-05	5	91	2	9000074
Pubmed	The embryonic development of hindbrain respiratory networks is unaffected by mutation of the planar polarity protein Scribble.	ISL2 ISL1	6.74e-05	5	91	2	28583412
Pubmed	Activation of Wnt signaling reduces ipsilaterally projecting retinal ganglion cells in pigmented retina.	ISL2 ISL1 LEF1	7.39e-05	31	91	3	30254141
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	UBAP2 ZNF532 TELO2 PHF12 TNRC6A CHSY1 EDEM1 ECPAS	7.65e-05	529	91	8	14621295
Pubmed	Genetic identification of an embryonic parafacial oscillator coupling to the preBötzinger complex.	ISL2 ISL1	1.01e-04	6	91	2	19578380
Pubmed	Necdin protects embryonic motoneurons from programmed cell death.	ISL2 ISL1	1.01e-04	6	91	2	21912643
Pubmed	Mammalian motoneuron axon targeting requires receptor protein tyrosine phosphatases sigma and delta.	ISL2 ISL1	1.01e-04	6	91	2	16738228
Pubmed	Generation of a novel functional neuronal circuit in Hoxa1 mutant mice.	ISL2 ISL1	1.01e-04	6	91	2	11466434
Pubmed	Glial cell line-derived neurotrophic factor and developing mammalian motoneurons: regulation of programmed cell death among motoneuron subtypes.	ISL2 ISL1	1.01e-04	6	91	2	10864958
Pubmed	LncRNA Litchi is a regulator for harmonizing maturity and resilient functionality in spinal motor neurons.	ISL2 ISL1	1.01e-04	6	91	2	38433925
Pubmed	Regulation of continuous but complex expression pattern of Six1 during early sensory development.	ISL2 ISL1	1.01e-04	6	91	2	29106072
Pubmed	Mouse Dll3: a novel divergent Delta gene which may complement the function of other Delta homologues during early pattern formation in the mouse embryo.	ISL2 ISL1	1.01e-04	6	91	2	9272948
Pubmed	Heterogeneous Origin of Gonadotropin Releasing Hormone-1 Neurons in Mouse Embryos Detected by Islet-1/2 Expression.	ISL2 ISL1	1.01e-04	6	91	2	32083082
Pubmed	Pax6 influences the time and site of origin of glial precursors in the ventral neural tube.	ISL2 ISL1	1.01e-04	6	91	2	9828088
Pubmed	Glia-specific enhancers and chromatin structure regulate NFIA expression and glioma tumorigenesis.	ISL2 ISL1	1.01e-04	6	91	2	28892058
Pubmed	Semaphorin 3A-Neuropilin-1 signaling regulates peripheral axon fasciculation and pathfinding but not developmental cell death patterns.	ISL2 ISL1	1.01e-04	6	91	2	20345923
Pubmed	ABL kinases regulate the stabilization of HIF-1α and MYC through CPSF1.	ABL2 CPSF1	1.01e-04	6	91	2	37040401
Pubmed	Juxtaposition of CNR protocadherins and reelin expression in the developing spinal cord.	ISL2 ISL1	1.01e-04	6	91	2	11312598
Pubmed	The HMG box transcription factor gene Sox14 marks a novel subset of ventral interneurons and is regulated by sonic hedgehog.	ISL2 ISL1	1.01e-04	6	91	2	10677261
Pubmed	Netrin-1 acts as a repulsive guidance cue for sensory axonal projections toward the spinal cord.	ISL2 ISL1	1.01e-04	6	91	2	18842897
Pubmed	Short-term lineage analysis of dorsally derived Olig3 cells in the developing spinal cord.	ISL2 ISL1	1.01e-04	6	91	2	16145668
Pubmed	RAG-2 deficiency results in fewer phosphorylated histone H2AX foci, but increased retinal ganglion cell death and altered axonal growth.	ISL2 ISL1	1.01e-04	6	91	2	31811168
Pubmed	Integrity of developing spinal motor columns is regulated by neural crest derivatives at motor exit points.	ISL2 ISL1	1.01e-04	6	91	2	12575949
Pubmed	Spatiotemporal features of early neuronogenesis differ in wild-type and albino mouse retina.	ISL2 ISL1	1.01e-04	6	91	2	12040030
Pubmed	Activation of Six1 Expression in Vertebrate Sensory Neurons.	ISL2 ISL1	1.01e-04	6	91	2	26313368
Pubmed	Breathing without CO(2) chemosensitivity in conditional Phox2b mutants.	ISL2 ISL1	1.01e-04	6	91	2	21900566
Pubmed	Kelch Domain of Gigaxonin Interacts with Intermediate Filament Proteins Affected in Giant Axonal Neuropathy.	SYNE2 RPS10 DMD CFAP44 TRRAP	1.36e-04	187	91	5	26460568
Pubmed	Zic2 patterns binocular vision by specifying the uncrossed retinal projection.	ISL2 ISL1	1.41e-04	7	91	2	13678579
Pubmed	Development in the absence of skeletal muscle results in the sequential ablation of motor neurons from the spinal cord to the brain.	ISL2 ISL1	1.41e-04	7	91	2	10075844
Pubmed	Isl1 is required for multiple aspects of motor neuron development.	ISL2 ISL1	1.41e-04	7	91	2	21569850
Pubmed	Chondroitin sulfate N-acetylgalactosaminyltransferase-1 plays a critical role in chondroitin sulfate synthesis in cartilage.	CHSY1 CHSY3	1.41e-04	7	91	2	17145758
Pubmed	Mice deficient in the chemokine receptor CXCR4 exhibit impaired limb innervation and myogenesis.	ISL2 ISL1	1.41e-04	7	91	2	16198599
Pubmed	TWH regulates the development of subsets of spinal cord neurons.	ISL2 ISL1	1.41e-04	7	91	2	9136764
Pubmed	A postmitotic role for Isl-class LIM homeodomain proteins in the assignment of visceral spinal motor neuron identity.	ISL2 ISL1	1.41e-04	7	91	2	14766174
Pubmed	STAT3 promotes motor neuron differentiation by collaborating with motor neuron-specific LIM complex.	ISL2 ISL1	1.41e-04	7	91	2	23798382
Pubmed	GFRalpha 1 is required for development of distinct subpopulations of motoneuron.	ISL2 ISL1	1.41e-04	7	91	2	10864957
Pubmed	Dehydroepiandrosterone biosynthesis, role, and mechanism of action in the developing neural tube.	ISL2 ISL1	1.41e-04	7	91	2	22649409
Pubmed	MuSK controls where motor axons grow and form synapses.	ISL2 ISL1	1.41e-04	7	91	2	18084289
Pubmed	UNC5A promotes neuronal apoptosis during spinal cord development independent of netrin-1.	ISL2 ISL1	1.41e-04	7	91	2	16829956
Pubmed	Expression of secreted semaphorins and their receptors in specific neuromeres, boundaries, and neuronal groups in the developing mouse and chick brain.	ISL2 ISL1	1.41e-04	7	91	2	16360650
Pubmed	The nuclear LIM domain interactor NLI mediates homo- and heterodimerization of LIM domain transcription factors.	ISL2 ISL1	1.41e-04	7	91	2	9452425
Pubmed	Region- and cell type-selective expression of the evolutionarily conserved Nolz-1/zfp503 gene in the developing mouse hindbrain.	ISL2 ISL1	1.41e-04	7	91	2	21945624
Pubmed	A genetic and physiological study of impaired glucose homeostasis control in C57BL/6J mice.	ISL2 ISL1	1.41e-04	7	91	2	15729571
Pubmed	Patterns of neuronal differentiation in neural tube mutant mice: curly tail and Pax3 splotch-delayed.	ISL2 ISL1	1.41e-04	7	91	2	8744440
Pubmed	From Otic Induction to Hair Cell Production: Pax2EGFP Cell Line Illuminates Key Stages of Development in Mouse Inner Ear Organoid Model.	ISL2 ISL1	1.41e-04	7	91	2	29272992
Pubmed	Attenuated Epigenetic Suppression of Muscle Stem Cell Necroptosis Is Required for Efficient Regeneration of Dystrophic Muscles.	RIPK3 DMD	1.41e-04	7	91	2	32433961
Pubmed	Diverse expression patterns of LIM-homeodomain transcription factors (LIM-HDs) in mammalian inner ear development.	ISL2 ISL1	1.41e-04	7	91	2	18942141
Pubmed	Adenylate Cyclase 1 modulates peripheral nerve branching patterns.	ISL2 ISL1	1.41e-04	7	91	2	20692345
Pubmed	Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	SYNE2 SSX2IP CHSY1 TRAPPC8	1.53e-04	102	91	4	10231032
Interaction	PRICKLE2 interactions	ARHGAP15 SYNE2 PRICKLE2 DMD TRRAP STRIP2	2.75e-07	62	87	6	int:PRICKLE2
Interaction	SRGAP1 interactions	ARHGAP15 RAPH1 SYNE2 PRICKLE2 DMD STRIP2	2.88e-06	92	87	6	int:SRGAP1
Interaction	PRICKLE1 interactions	ARHGAP15 SYNE2 PRICKLE2 DMD STRIP2	6.05e-06	60	87	5	int:PRICKLE1
Interaction	FGD4 interactions	ARHGAP15 SYNE2 PRICKLE2 LANCL1 STRIP2	8.33e-06	64	87	5	int:FGD4
Interaction	ARHGAP26 interactions	ARHGAP15 SYNE2 PRICKLE2 PDS5A DMD STRIP2	1.34e-05	120	87	6	int:ARHGAP26
Interaction	GNAL interactions	ARHGAP15 SYNE2 PRICKLE2 TRRAP	1.92e-05	37	87	4	int:GNAL
Interaction	CHN2 interactions	ARHGAP15 SYNE2 PRICKLE2 DMD STRIP2	6.30e-05	97	87	5	int:CHN2
Cytoband	1p22	TTF2 CDC7	7.21e-04	20	91	2	1p22
Cytoband	Ensembl 112 genes in cytogenetic band chr7q22	POLR2J3 SPDYE2 POLR2J2 TRRAP	9.73e-04	219	91	4	chr7q22
Cytoband	8p21.2	ADRA1A ADAM28	1.13e-03	25	91	2	8p21.2
Cytoband	18q12.1	DSG2 TRAPPC8	1.22e-03	26	91	2	18q12.1
Cytoband	7q22.1	POLR2J3 SPDYE2 POLR2J2	1.51e-03	113	91	3	7q22.1
Cytoband	4q13.2	CENPC UGT2B28	1.74e-03	31	91	2	4q13.2
Cytoband	Ensembl 112 genes in cytogenetic band chr7q11	SPDYE21 SPDYE5 SPDYE18 SPDYE16	2.12e-03	271	91	4	chr7q11
Cytoband	Ensembl 112 genes in cytogenetic band chr8p21	ADRA1A INTS9 ADAM28	2.50e-03	135	91	3	chr8p21
GeneFamily	Speedy/RINGO cell cycle regulator family	SPDYE1 SPDYE2 SPDYE5	7.87e-06	12	61	3	756
GeneFamily	Non-clustered protocadherins	PCDH11Y PCDH12	7.23e-04	12	61	2	21
GeneFamily	LIM class homeoboxes	ISL2 ISL1	7.23e-04	12	61	2	522
GeneFamily	Beta 4-glycosyltransferases	CHSY1 CHSY3	1.47e-03	17	61	2	425
GeneFamily	Beta 3-glycosyltransferases	CHSY1 CHSY3	2.95e-03	24	61	2	426
GeneFamily	RNA polymerase subunits	POLR2J3 POLR2J2	4.29e-03	29	61	2	726
Coexpression	TRAVAGLINI_LUNG_CD4_MEMORY_EFFECTOR_T_CELL	GSTK1 ARHGAP15 SYNE2 SPOCK2 LEF1	4.40e-06	71	89	5	M41683
ToppCell	COVID-19_Moderate-CD4+_T_activated\|World / disease group, cell group and cell class	PNPT1 ARHGAP15 SHFL SYNE2 RPS10 SPOCK2 LEF1	1.33e-07	193	90	7	c2a2a2c14a7085690262db5c2a70e38db67dee18
ToppCell	severe_influenza-CD4+_Tcm\|World / disease group, cell group and cell class (v2)	GSTK1 ARHGAP15 SYNE2 RPS10 SPOCK2 LEF1	9.63e-07	162	90	6	7137990e6e1473665911e39a22092a05ae25ce74
ToppCell	systemic_lupus_erythematosus-treated-Lymphocytic_T-T4_reg-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	GSTK1 ARHGAP15 SYNE2 RPS10 SPOCK2 LEF1	1.67e-06	178	90	6	90dedb3cef9b01907b9f8eec64218d6d2072be1f
ToppCell	systemic_lupus_erythematosus-treated-Lymphocytic_T-T4_reg\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	GSTK1 ARHGAP15 SYNE2 RPS10 SPOCK2 LEF1	1.67e-06	178	90	6	d6312286bf6cc5b107ccd7adb583d9667d4e1d21
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_T-T4_reg\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	GSTK1 ARHGAP15 SYNE2 RPS10 SPOCK2 LEF1	2.29e-06	188	90	6	e5c480b9a030536578f1cc91fb61738f752525b3
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	CENPC PHF12 SYNE2 SPOCK2 LEF1 IL5	2.43e-06	190	90	6	91ba66d4b56c59523485b17738e93f14bb00afa4
ToppCell	systemic_lupus_erythematosus-treated-Lymphocytic_T-T4_em\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	GSTK1 ARHGAP15 SYNE2 RPS10 SPOCK2 LEF1	2.43e-06	190	90	6	1634a6044dce4e026a63976031a498c7460e3dce
ToppCell	systemic_lupus_erythematosus-treated-Lymphocytic_T-T4_em-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	GSTK1 ARHGAP15 SYNE2 RPS10 SPOCK2 LEF1	2.43e-06	190	90	6	08813c2f9321b82f0ec66854bb7a383aa1171780
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_T-T4_reg-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	GSTK1 ARHGAP15 SYNE2 RPS10 SPOCK2 LEF1	2.51e-06	191	90	6	c5e22df4a8741b8096cdd1618271fd48d6265846
ToppCell	COVID-19_Moderate-CD4+_T_activated\|COVID-19_Moderate / disease group, cell group and cell class	PNPT1 ARHGAP15 SHFL RPS10 SPOCK2 LEF1	2.58e-06	192	90	6	7a81652406332afd03a9b3b529e9b5e6c0b54c28
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_T-T4_em\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	GSTK1 ARHGAP15 SYNE2 RPS10 SPOCK2 LEF1	2.58e-06	192	90	6	e07b6892276c81c1227e94ca942f6820d89a7ca3
ToppCell	Healthy-CD4+_Tcm\|Healthy / disease group, cell group and cell class	GSTK1 ARHGAP15 SYNE2 RPS10 SPOCK2 LEF1	2.74e-06	194	90	6	85c2c4f6b87a50b67903770a2dc74da765757c6d
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_T-T4_em-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	GSTK1 ARHGAP15 SYNE2 RPS10 SPOCK2 LEF1	2.74e-06	194	90	6	0b0042b6a356a49a059fb64a1e1abb25c82d48cf
ToppCell	Healthy-CD4+_Tcm\|World / disease group, cell group and cell class	GSTK1 ARHGAP15 SYNE2 RPS10 SPOCK2 LEF1	2.91e-06	196	90	6	cf19bc920f3ef07a87a2cdcb43f9f5855ef1fa9a
ToppCell	Sepsis-ICU-SEP-Lymphocyte-T/NK-Treg\|ICU-SEP / Disease, condition lineage and cell class	FSIP2 SYNE2 SPOCK2 CLNK LEF1 CDC7	2.99e-06	197	90	6	c3ee2d522fbfe67069ddba2d1abfc4f5ca230c26
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	GSTK1 ARHGAP15 CENPC SYNE2 SPOCK2 LEF1	3.08e-06	198	90	6	8a7897d98f5296745d9005a7cd777f0a2f78000d
ToppCell	10x_5'_v1-Non-neoplastic-Lymphoid-CD4/CD8-CD4_INF-Z\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	PNPT1 GSTK1 SHFL BAZ1A SYNE2 SPOCK2	3.17e-06	199	90	6	d3f36ede2fade550ec8f21a0448e71e1ff579ee2
ToppCell	severe-CD4+_Tcm\|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	GSTK1 ARHGAP15 SYNE2 RPS10 SPOCK2 LEF1	3.27e-06	200	90	6	46298dfa836a9f04d235939402571f7d5c10dfda
ToppCell	Striatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Drd1\|Striatum / BrainAtlas - Mouse McCarroll V32	TERB1 ISL1 CLNK CDCP1 STRIP2	1.18e-05	146	90	5	7b863f9bc63dc1afe015a18a70cd6ed0b71d1f09
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c06-NR4A2\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ARHGAP15 CENPC SYNE2 SPOCK2 LEF1	1.95e-05	162	90	5	80317c4253bf8e897782e562f29835f181c65b98
ToppCell	Thalamus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Six3\|Thalamus / BrainAtlas - Mouse McCarroll V32	FSIP2 CHSY3 ISL1 CCDC7	2.32e-05	82	90	4	47b131333ab84b70d2abe3fc17e63de504214b1b
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c12-FOXP3\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	GSTK1 SYNE2 SPOCK2 RASSF8 CDC7	2.83e-05	175	90	5	16c835e62a3321f6cf6163954889946bbb869498
ToppCell	PBMC-Severe-Lymphocyte-T/NK-CD4+_T-Treg-Treg_2\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	GSTK1 POLR2J3 SYNE2 SPOCK2 LEF1	3.15e-05	179	90	5	593fc323b28304a57ae162f64b0890b893fff446
ToppCell	PBMC-Severe-Lymphocyte-T/NK-CD4+_T-Treg-Treg_2\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	GSTK1 POLR2J3 SYNE2 SPOCK2 LEF1	3.15e-05	179	90	5	708fc0b8ffcb5fac43c52541acb6671fe1cfbb0d
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c06-NR4A2\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	GSTK1 ARHGAP15 SYNE2 SPOCK2 LEF1	3.41e-05	182	90	5	9ba85f621a846531a2a7861e9df695d288c9e149
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	ARHGAP15 SYNE2 TNRC6A SPOCK2 LEF1	3.50e-05	183	90	5	f2ef110bf29b1a8276ef216238363e542db262c1
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	TTF2 ARHGAP15 SYNE2 LANCL1 LEF1	3.59e-05	184	90	5	bd786db4dc4edae6d5cfc0b69901983dea19f729
ToppCell	COVID-CD4-naive_CD4\|COVID / Condition, Cell_class and T cell subcluster	GSTK1 ARHGAP15 SYNE2 SPOCK2 LEF1	3.59e-05	184	90	5	00db55970d336a301035efe43a4ab4db62627f38
ToppCell	systemic_lupus_erythematosus-treated-Lymphocytic_T-CD4-positive,_alpha-beta_T_cell-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	ARHGAP15 SYNE2 RPS10 SPOCK2 LEF1	3.69e-05	185	90	5	406b52516b26e9fe2c9e768950af447ec7ad5f3e
ToppCell	LPS_only-Epithelial_alveolar-AT_1-AT1-AT2\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PARD6B DSG2 GALNT5 CLNK CDCP1	3.69e-05	185	90	5	68f428e169cfb77de970bdfdeea9b9f16f68d2ba
ToppCell	systemic_lupus_erythematosus-treated-Lymphocytic_T-CD4-positive,_alpha-beta_T_cell\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	ARHGAP15 SYNE2 RPS10 SPOCK2 LEF1	3.69e-05	185	90	5	f2ebd099c8dfcfaca4298bcdd618c50701a9c2c8
ToppCell	Control-Lymphocyte-T_NK-CD4_TCM\|Control / Disease, Lineage and Cell Type	GSTK1 ARHGAP15 SYNE2 SPOCK2 LEF1	3.88e-05	187	90	5	1de80f40f753b31aed1fac9f3ff8a2ee6c755eec
ToppCell	ICU-NoSEP-Lymphocyte-T_NK-CD4_TCM\|ICU-NoSEP / Disease, Lineage and Cell Type	GSTK1 ARHGAP15 SYNE2 SPOCK2 LEF1	3.88e-05	187	90	5	9856e0ddf989707e2a25ed6ab75bd9fa939c9046
ToppCell	T_cells-ISG-high_CD4+_T_cells\|World / Immune cells in Kidney/Urine in Lupus Nephritis	PNPT1 SHFL SYNE2 SPOCK2 LEF1	3.98e-05	188	90	5	6f8946d4710f6e32c937213f99b790b098b8819c
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c04-ANXA2\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	GSTK1 ARHGAP15 SYNE2 SPOCK2 LEF1	3.98e-05	188	90	5	fe08277d5aa693a2e12786738d12ec6390e8d13d
ToppCell	normal-na-Lymphocytic_T-T4_reg-female\|normal / PBMC cell types (v2) per disease, treatment status, and sex	GSTK1 ARHGAP15 SYNE2 SPOCK2 LEF1	4.19e-05	190	90	5	d8c1998eb02d5105598608d4733b63978ffa3eb2
ToppCell	normal-na-Lymphocytic_T-T4_reg\|normal / PBMC cell types (v2) per disease, treatment status, and sex	GSTK1 ARHGAP15 SYNE2 SPOCK2 LEF1	4.19e-05	190	90	5	b8897c3e0fe8bb7efaf6a3787104d454d81a4c92
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_T-T4_em-male\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	GSTK1 ARHGAP15 SYNE2 SPOCK2 LEF1	4.19e-05	190	90	5	f6616b3fe7f4962249503c96c06926240066d861
ToppCell	severe_COVID-19-CD4+_Tcm\|severe_COVID-19 / disease group, cell group and cell class (v2)	GSTK1 ARHGAP15 SYNE2 SPOCK2 LEF1	4.29e-05	191	90	5	1ec86eaf90411ed200dbf51ae0cb5ed8060a7ec7
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ARHGAP15 SYNE2 TNRC6A SPOCK2 LEF1	4.29e-05	191	90	5	d9a6f61fcda4f5352488f7f55cb9b57aeacc717f
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c04-ANXA2\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	GSTK1 ARHGAP15 SYNE2 SPOCK2 LEF1	4.29e-05	191	90	5	9c747f8cc1cdce45e839b661d782e1e8cfb79578
ToppCell	COVID-19_Moderate-CD4+_Tcm\|World / disease group, cell group and cell class	GSTK1 ARHGAP15 SYNE2 SPOCK2 LEF1	4.40e-05	192	90	5	5f94310f1470487816fce697ffcdc2627fc66878
ToppCell	390C-Lymphocytic-CD4_T-cell-CD4+_Naive_T_cell_/_CD4+_Trm_cell\|390C / Donor, Lineage, Cell class and subclass (all cells)	GSTK1 ARHGAP15 RPS10 SPOCK2 LEF1	4.40e-05	192	90	5	494c5eca0f07fc761f26487a2b937c7056bbe594
ToppCell	COVID-19_Severe-CD4+_Tcm\|World / disease group, cell group and cell class	ARHGAP15 SYNE2 RPS10 SPOCK2 LEF1	4.40e-05	192	90	5	3352f13a6e706991dcf3ec173587bb6aba36a385
ToppCell	356C-Lymphocytic-CD4_T-cell-CD4+_Naive_T_cell_/_CD4+_Trm_cell\|356C / Donor, Lineage, Cell class and subclass (all cells)	GSTK1 ARHGAP15 RPS10 SPOCK2 LEF1	4.40e-05	192	90	5	7aa8585e08dfbee0acbaef5f8f3817ab3ab5af25
ToppCell	Healthy_donor-CD4+_Tcm\|World / disease group, cell group and cell class (v2)	GSTK1 ARHGAP15 SYNE2 SPOCK2 LEF1	4.40e-05	192	90	5	1603903454ba6bf65c8e13ede620e0b1e8fbd7ec
ToppCell	356C-Lymphocytic-CD4_T-cell\|356C / Donor, Lineage, Cell class and subclass (all cells)	GSTK1 ARHGAP15 RPS10 SPOCK2 LEF1	4.40e-05	192	90	5	badf72a52eafb0269391d907ece6b1696684adce
ToppCell	systemic_lupus_erythematosus-managed-Lymphocytic_T-T4_reg\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	GSTK1 ARHGAP15 SYNE2 SPOCK2 LEF1	4.51e-05	193	90	5	2a06bb3d6bbe544a26dc42d94a10f60acfd3600b
ToppCell	systemic_lupus_erythematosus-managed-Lymphocytic_T-T4_reg-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	GSTK1 ARHGAP15 SYNE2 SPOCK2 LEF1	4.51e-05	193	90	5	b4f8afd871fdf9418b92ff419c8ba9739b6093ca
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	GSTK1 ARHGAP15 SYNE2 SPOCK2 LEF1	4.51e-05	193	90	5	194b49c152e3e3f599068ec88a7f0af6427b743a
ToppCell	T_cells-Central_memory_CD4+_T_cells\|World / Immune cells in Kidney/Urine in Lupus Nephritis	GSTK1 ARHGAP15 SYNE2 SPOCK2 LEF1	4.51e-05	193	90	5	725326d7e3604736b607c19f4069c81cb4f2d20c
ToppCell	RV-10._Endothelium_II\|World / Chamber and Cluster_Paper	HMCN1 RAPH1 SYNE2 CHSY1 OPCML	4.51e-05	193	90	5	2531266bc57339d4e2b22a88817008e32b8c1598
ToppCell	COVID-19_Severe-CD4+_Tcm\|COVID-19_Severe / disease group, cell group and cell class	GSTK1 ARHGAP15 SYNE2 SPOCK2 LEF1	4.51e-05	193	90	5	45fe14c10b71459047608c8931d83c9c533f97f9
ToppCell	PBMC-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_Tcm-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	GSTK1 ARHGAP15 SYNE2 SPOCK2 LEF1	4.62e-05	194	90	5	929b97eb0a4a88cd566f832d4959b8b8a34c46b4
ToppCell	NS-critical-d_07-13-Epithelial-Secretory\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	FREM2 DSG2 ISL1 GALNT5 ADAM28	4.62e-05	194	90	5	2172d951896265243d14996eacce5aab5e14e26e
ToppCell	PBMC-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_Tcm\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	GSTK1 ARHGAP15 SYNE2 SPOCK2 LEF1	4.62e-05	194	90	5	4bcbea5dc0c91c51fbb6b0f7de1e47010c62812a
ToppCell	Healthy/Control-CD4+_Tcm\|World / Disease group and Cell class	GSTK1 ARHGAP15 SYNE2 SPOCK2 LEF1	4.62e-05	194	90	5	cbdd1786305108cbeddea07a21120067d78c59a0
ToppCell	COVID-19_Mild-Lymphoid_T/NK-CD4+_Tcm\|COVID-19_Mild / Disease group, lineage and cell class	GSTK1 ARHGAP15 SYNE2 SPOCK2 LEF1	4.62e-05	194	90	5	0aad8c7f356d54346af764e0cc4edce89c6daabb
ToppCell	systemic_lupus_erythematosus-treated-Lymphocytic_T\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	ARHGAP15 SYNE2 RPS10 SPOCK2 LEF1	4.62e-05	194	90	5	9588a9b4baebbae08e13d201d4b9dfcf0e6521fb
ToppCell	T/NK_cells-Regulatory_T_cell\|World / Lineage and Cell class	GSTK1 ARHGAP15 SYNE2 RPS10 SPOCK2	4.62e-05	194	90	5	4f55da763f63d1bf6379582e9d85796a797c5b76
ToppCell	COVID-19_Moderate-CD4+_Tcm\|COVID-19_Moderate / disease group, cell group and cell class	GSTK1 ARHGAP15 SYNE2 SPOCK2 LEF1	4.62e-05	194	90	5	346ab9801366501453cedd3cb7cdfb63b7e7ddf6
ToppCell	PBMC-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_Tcm\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	GSTK1 ARHGAP15 SYNE2 SPOCK2 LEF1	4.62e-05	194	90	5	8c3c04770913724b4e93941b547402052ae352c2
ToppCell	mild_COVID-19-CD4+_Tcm\|mild_COVID-19 / disease group, cell group and cell class (v2)	GSTK1 ARHGAP15 SYNE2 SPOCK2 LEF1	4.62e-05	194	90	5	cf085813138a73878f9586059cd1d01d1a7ee748
ToppCell	PBMC-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_Tcm-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	GSTK1 ARHGAP15 SYNE2 SPOCK2 LEF1	4.62e-05	194	90	5	884b5c98a1fdc651d7f4a0fad2a5965859207abc
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	GSTK1 ARHGAP15 SYNE2 SPOCK2 LEF1	4.62e-05	194	90	5	a44be2f021cfdd0fcdc698c3f04d66db7a1aa6c2
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_T-CD4-positive,_alpha-beta_T_cell-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	ARHGAP15 SYNE2 RPS10 SPOCK2 LEF1	4.74e-05	195	90	5	07035a5972a78b98e4ab2167e3a5000f9f3b0826
ToppCell	mild_COVID-19-CD4+_Tcm\|World / disease group, cell group and cell class (v2)	GSTK1 ARHGAP15 SYNE2 SPOCK2 LEF1	4.74e-05	195	90	5	fc666cd4d00df9cc03127fb73032ae3e46419055
ToppCell	COVID-19_Severe-Lymphoid_T/NK-CD4+_Tcm\|COVID-19_Severe / Disease group, lineage and cell class	GSTK1 ARHGAP15 SYNE2 SPOCK2 LEF1	4.74e-05	195	90	5	658751e384de50cdcb907d3740fb1a74004a517b
ToppCell	COVID-19_Mild-PLT_5\|COVID-19_Mild / Disease Group and Platelet Clusters	PNPT1 PHC3 SYNE2 SPOCK2 LEF1	4.74e-05	195	90	5	bdf9a6ea1bd83c72a834c45f86ce3f4643a9bef3
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_T-CD4-positive,_alpha-beta_T_cell\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	ARHGAP15 SYNE2 RPS10 SPOCK2 LEF1	4.74e-05	195	90	5	5001e68df2ad5df9dc93ae235f984ffafea6b521
ToppCell	PBMC-Severe-Lymphocyte-T/NK-CD4+_T-CD4+_Tcm-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	GSTK1 ARHGAP15 SYNE2 SPOCK2 LEF1	4.74e-05	195	90	5	e3e5c784e7b494434fb4f6f27e0af22b167842ef
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_T\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	ARHGAP15 SYNE2 RPS10 SPOCK2 LEF1	4.74e-05	195	90	5	53528e5788083bce5a8d4611ab3808878e6a9cd3
ToppCell	systemic_lupus_erythematosus-managed-Lymphocytic_T-T4_em-male\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	GSTK1 ARHGAP15 SYNE2 RPS10 SPOCK2	4.74e-05	195	90	5	48905d57775ec90cc031af0863cc8c3800f2e48e
ToppCell	PBMC-Severe-Lymphocyte-T/NK-CD4+_T-CD4+_Tcm\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	GSTK1 ARHGAP15 SYNE2 SPOCK2 LEF1	4.74e-05	195	90	5	d6b8bc4204476220a64afe17e3b6b2ed59853284
ToppCell	PBMC-Control-Lymphocyte-T/NK-CD4+_T-CD4+_Tcm\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	GSTK1 ARHGAP15 RPS10 SPOCK2 LEF1	4.85e-05	196	90	5	1f09d0a653c0ccc4d643066289f1cf1b3d6845a5
ToppCell	PBMC-Severe-Lymphocyte-T/NK-CD4+_T-CD4+_Tcm\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	GSTK1 ARHGAP15 SYNE2 SPOCK2 LEF1	4.85e-05	196	90	5	459408882babf1fb56b37dc52ec119ac0b0153a7
ToppCell	Multiple_Sclerosis-Lymphocyte-T_NK-CD4_TCM\|Multiple_Sclerosis / Disease, Lineage and Cell Type	GSTK1 ARHGAP15 RPS10 SPOCK2 LEF1	4.85e-05	196	90	5	30c31f3d2c1fb3667c5c7f2057eca067dcd69e4d
ToppCell	3'_v3-Lung-Lymphocytic_T_CD4-Teffector/EM_CD4\|Lung / Manually curated celltypes from each tissue	ARHGAP15 SYNE2 RPS10 SPOCK2 LEF1	4.85e-05	196	90	5	0d6eead0ab4b6150f3a91ea0e25ea2c61f43184b
ToppCell	systemic_lupus_erythematosus-managed-Lymphocytic_T-T4_em-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	GSTK1 ARHGAP15 SYNE2 SPOCK2 LEF1	4.85e-05	196	90	5	ea3caea65e8ddd20a837b4322e7940328c94c15a
ToppCell	PBMC-Severe-Lymphocyte-T/NK-CD4+_T-CD4+_Tcm-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	GSTK1 ARHGAP15 SYNE2 SPOCK2 LEF1	4.85e-05	196	90	5	a1a1e4e4404a0c590edd07dfc9e7e1b6f720fb0f
ToppCell	Control-Lymphoid_T/NK-CD4+_Tcm\|Control / Disease group, lineage and cell class	GSTK1 ARHGAP15 RPS10 SPOCK2 LEF1	4.85e-05	196	90	5	9a90fec4b07e07c9a3ea4d1e6c05c4b7ec699942
ToppCell	systemic_lupus_erythematosus-managed-Lymphocytic_T-T4_em\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	GSTK1 ARHGAP15 SYNE2 SPOCK2 LEF1	4.85e-05	196	90	5	f7af0af02059aefb968b72a2a27867ad8ff23614
ToppCell	PBMC-Control-Lymphocyte-T/NK-CD4+_T-CD4+_Tcm-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	GSTK1 ARHGAP15 RPS10 SPOCK2 LEF1	4.85e-05	196	90	5	128bda047ffeb47fa983873737ff42603f5ffd5a
ToppCell	PBMC-Control-Lymphocyte-T/NK-CD4+_T-CD4+_Tcm\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	GSTK1 ARHGAP15 RPS10 SPOCK2 LEF1	4.85e-05	196	90	5	233e77aa6302f714326ce1211f8405ebd520933c
ToppCell	PBMC-Control-Lymphocyte-T/NK-CD4+_T-CD4+_Tcm-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	GSTK1 ARHGAP15 RPS10 SPOCK2 LEF1	4.85e-05	196	90	5	f85c6e1f004726608238088d46c369838c7157c7
ToppCell	IIH-CD4\|IIH / Condition, Cell_class and T cell subcluster	GSTK1 ARHGAP15 SYNE2 SPOCK2 LEF1	4.85e-05	196	90	5	d6c92c91e17230a6ef0cfaea476d560691ed5d98
ToppCell	BLOOD--(1)_T_cell\| / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	ARHGAP15 SYNE2 RPS10 SPOCK2 LEF1	4.85e-05	196	90	5	9dda5d10f1eecf5322cae467e337e2fb92d8e3a1
ToppCell	PBMC-Severe-Lymphocyte-T/NK-CD4+_T\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	GSTK1 ARHGAP15 SYNE2 SPOCK2 LEF1	4.97e-05	197	90	5	33d841f4fcff8aeb0b988d5dd072166347bc6022
ToppCell	healthy_donor-Lymphocytic-T_cell-CD4+_Memory_T_cell\|healthy_donor / Disease condition, Lineage, Cell class and subclass	GSTK1 ARHGAP15 SYNE2 SPOCK2 LEF1	4.97e-05	197	90	5	c842d169dfce9af3ed7c01dc7e940c0bdd21388c
ToppCell	PBMC-Severe-Lymphocyte-T/NK-CD4+_T\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	GSTK1 ARHGAP15 SYNE2 SPOCK2 LEF1	4.97e-05	197	90	5	7f686353e1e08e0a0f721a6806c92d05254a77b2
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_T_CD4-Teffector/EM_CD4\|lymph-node_spleen / Manually curated celltypes from each tissue	GSTK1 ARHGAP15 SYNE2 SPOCK2 LEF1	4.97e-05	197	90	5	c4603bfe9ab537ca64172f65203a5d23671f7354
ToppCell	3'_v3-bone_marrow-Lymphocytic_T_CD4-Teffector/EM_CD4\|bone_marrow / Manually curated celltypes from each tissue	GSTK1 ARHGAP15 RPS10 SPOCK2 LEF1	4.97e-05	197	90	5	73a13d4dc76476f3a38b09b776779c5b7d67171f
ToppCell	3'_v3-lymph-node_spleen-Lymphocytic_T_CD4-Teffector/EM_CD4\|lymph-node_spleen / Manually curated celltypes from each tissue	GSTK1 ARHGAP15 SYNE2 RPS10 SPOCK2	4.97e-05	197	90	5	b3808ad7b1562a51c6b99dd40c78433fac722e3a
ToppCell	control-Treg\|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	GSTK1 SYNE2 SPOCK2 LEF1 CCDC7	4.97e-05	197	90	5	a80674a0b996aa57d52bfff7264c57caf4c31cc6
ToppCell	VE-CD4-memory_CD4\|VE / Condition, Cell_class and T cell subcluster	GSTK1 ARHGAP15 SYNE2 RPS10 SPOCK2	5.09e-05	198	90	5	ef580576d6669ac7051e8f93fec2f2cd3887e64e
ToppCell	Influenza-Influenza_Severe-Lymphocyte-T/NK-CD4+_Tcm\|Influenza_Severe / Disease, condition lineage and cell class	GSTK1 ARHGAP15 SYNE2 SPOCK2 LEF1	5.09e-05	198	90	5	fc99f2e300d76126d05c0c43e11cdbbeb74f6f0d
ToppCell	Bronchial-NucSeq-Immune_Lymphocytic-T-T_CD4-T_reg\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ARHGAP15 SYNE2 SPOCK2 CLNK LEF1	5.09e-05	198	90	5	7608f67959e1cda7b10e57fd3af2f96216ebe7e9
ToppCell	mild-CD4+_Tcm\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	GSTK1 ARHGAP15 SYNE2 SPOCK2 LEF1	5.22e-05	199	90	5	06c8a0e39f7a33736548f04a5e2263334c8541cf
ToppCell	VE-CD4-antiviral_CD4\|VE / Condition, Cell_class and T cell subcluster	PNPT1 GSTK1 SHFL SYNE2 SPOCK2	5.22e-05	199	90	5	056a0538ca5e825ae6195b4c76c208708a014533
ToppCell	10x5'-Lung-Lymphocytic_T_CD4\|Lung / Manually curated celltypes from each tissue	GSTK1 ARHGAP15 SYNE2 SPOCK2 LEF1	5.22e-05	199	90	5	32b9f19579448f1775ecb7974c29c60334513c88
Disease	skin conductance response frequency, electrodermal activity measurement	ARHGAP15 TNRC6A	2.46e-05	3	85	2	EFO_0006866, EFO_0006869
Disease	Malignant neoplasm of breast	ADRA1A RAPH1 ZNF532 SYNE2 CTIF GALNT5 DMD TRAPPC8 CYB5R4 LEF1 ZNF546	2.57e-04	1074	85	11	C0006142
Disease	Diverticular Diseases	ARHGAP15 ISL2	6.27e-04	13	85	2	C4317009
Disease	Diverticular Bleeding	ARHGAP15 ISL2	6.27e-04	13	85	2	C4505353
Disease	waist circumference	KLHL36 FAM222A SYNE2 MRPL30 DMD PIAS1	1.52e-03	429	85	6	EFO_0004342

Protein segments in the cluster

Peptide	Gene	Start	Entry
QVEKTLQLTPKPQHH	C2orf16	371	Q68DN1
KIFPTNIRVPQHKHL	FAM222A	61	Q5U5X8
HRKVRHTPKQPLPHI	CTIF	126	O43310
LHNLPLSPELKEKHN	CCDC7	26	Q96M83
THNHKVPVLISPTLK	ABL2	926	P42684
LHPLHKREAKEPEQQ	ADAM28	36	Q9UKQ2
KIARNHPNAKVLLHI	AZIN1	141	O14977
DNLIVHSRQPQKKPH	SSX2IP	506	Q9Y2D8
LVPAQKLQQHTHEKP	CDCP1	461	Q9H5V8
PSLDKNHQVPTIKVH	ADRA1A	441	P35348
RLKQQHEHKGLSPLP	DMD	3526	P11532
VQHFHKPALLPLLQR	PIK3AP1	76	Q6ZUJ8
LQKKLQHVPGTQPHL	CBWD5	256	Q5RIA9
VQLIRKHPQHNIKIG	DCLRE1B	166	Q9H816
EKQPSHHPLRIKKQL	DCLRE1B	386	Q9H816
IQSTLHISKHIPIPK	CFAP44	1241	Q96MT7
RDHSVQLPKPVHKPN	BAZ1A	876	Q9NRL2
RHLAPHENPIISLNK	RASSF8	51	Q8NHQ8
PLKIHQVQHITQVAP	RAPH1	746	Q70E73
IPILHQKAKRGTPHQ	PDS5A	721	Q29RF7
PFPHAELIQTNKLKH	INTS9	361	Q9NV88
PQKHIQKADIHLVPV	PCDH12	766	Q9NPG4
LTNVLRPDNHRKKPH	PARD6B	116	Q9BYG5
HVKPQHEQRKEQEPK	LEF1	281	Q9UJU2
HEQRKEQEPKRPHIK	LEF1	286	Q9UJU2
HPDHPLLLEAQRNIK	ARHGEF17	1231	Q96PE2
TRNENKLLPKHPHLV	DSG2	31	Q14126
KLLPKHPHLVRQKRA	DSG2	36	Q14126
HFPLIPKNDLLHRVK	KLHL36	236	Q8N4N3
RLIHLNKIDPHAPNE	LANCL1	136	O43813
LLRQTHPPHEKQELL	FREM2	611	Q5SZK8
LQKKLQHVPGTQPHL	CBWD2	256	Q8IUF1
LQKKLQHVPGTQPHL	CBWD1	256	Q9BRT8
ESHRPQKQSPLDIHL	FSIP2	4291	Q5CZC0
KSHHLQLQVIPVPIS	CWF19L1	411	Q69YN2
RLALHKPPLHHQSKV	CPSF1	681	Q10570
ILNKHIISPNPHVRQ	ECPAS	946	Q5VYK3
LKKKGIHHPTPIQIQ	DDX41	196	Q9UJV9
IKHQQIPLHSPPSKV	PHC3	306	Q8NDX5
CKHIHQKQETPQPPI	DPRX	76	A6NFQ7
SKHFILKVLEPPHIN	HMCN1	3516	Q96RW7
NHPKTSRVHLIVQVP	OPCML	121	Q14982
LRIKQLLHQLPPHDN	PRICKLE2	71	Q7Z3G6
ANETLRIPVPVHKNH	IL5	46	P05113
KNRIHHKLVLPSNTP	CENPC	721	Q03188
KIALKHLIPTSHPIR	CDC7	86	O00311
PELIKQIIKRHSNHL	FBXL3	96	Q9UKT7
VHSVINRSPPHLIKE	GALNT5	516	Q7Z7M9
KLLRHHLQIPIHFPK	GSTK1	71	Q9Y2Q3
LQKKLQHVPGTQPHL	CBWD3	256	Q5JTY5
LQKKLQHVPGTQPHL	CBWD6	256	Q4V339
SVHRPKPHELKVINS	EDEM1	611	Q92611
LETHTRLIKVKHPPQ	MBTPS2	391	O43462
QIQPETPLNLKHHII	PCDH11Y	981	Q9BZA8
RQPALRPHVHKQTEK	ISL2	176	Q96A47
PDSVLTHHVPRNLQK	MCM9	836	Q9NXL9
KVPHPLEHKIIIRVQ	POLR2J3	61	Q9H1A7
PRPIHESVKTLKQHK	STRIP2	456	Q9ULQ0
LEKAHTPQVHKNIPS	MRPL30	91	Q8TCC3
HHELSSKIKLPLPQL	SYNE2	4456	Q8WXH0
KVDFLNRIHKKHPPN	PHF12	351	Q96QT6
RNHSQHILKDVIPPL	ARHGAP15	61	Q53QZ3
HTPLPQQRHVSKAVL	TELO2	351	Q9Y4R8
RQPALRPHVHKQPEK	ISL1	166	P61371
TSALHPVHPDIKLQK	PIAS1	126	O75925
GHPLKNHNSLIPRKD	CYB5R4	256	Q7L1T6
LLHNTQLDQRKIKHP	PNPT1	706	Q8TCS8
HPVQPLALHVKAKKQ	SOX30	126	O94993
KVPHNQRKPESTHLL	CLNK	216	Q7Z7G1
KIHQAITLHPNKNPP	CHSY1	296	Q86X52
KIHAAITLHPNKRPA	CHSY3	386	Q70JA7
NISRPIHHPLVLKTN	C12orf50	71	Q8NA57
KVPHPLEHKIIIRVQ	POLR2J2	61	Q9GZM3
PKSRKQNHLPKVLHP	SHFL	226	Q9NUL5
KHPELADKNVPNLHV	RPS10	31	P46783
TPKQPVVRFKRNKHH	WDR47	646	O94967
HLFIVHKLKEPQPVS	ZNF532	1221	Q9HCE3
ISVSVHQPQPKHIKL	UBAP2	491	Q5T6F2
HQPQPKHIKLAKRRI	UBAP2	496	Q5T6F2
PQLNRHQKIHTGKKP	ZNF540	256	Q8NDQ6
PNKIEKHLLPEHIRR	MIPEP	226	Q99797
KHPELADKNVPNLHV	RPS10P5	31	Q9NQ39
LHDQNPVLLHRDLKP	RIPK3	131	Q9Y572
LKQQRVSPILPEHHK	SPDYE16	66	A6NNV3
LKQQRVSPILPEHHK	SPDYE18	106	P0DV79
LKQQRVSPILPEHHK	SPDYE21	106	A0A494C086
LKQQRVSPILPEHHK	SPDYE2	106	Q495Y8
LKQQRVSPILPEHHK	SPDYE5	106	A6NIY4
LKQQRVSPILLEHHK	SPDYE1	66	Q8NFV5
QISHPLHPKIHAREK	ZNF546	201	Q86UE3
LIIHQKTHPREKTPE	ZNF630	586	Q2M218
NHKKIHTITPVIPLL	ZNF91	1151	Q05481
ELKKPQAHLPVHTEK	TRAPPC8	1206	Q9Y2L5
LKQQRVSPILPEHHK	nan	66	A6NJR5
KIIPHSRVAKPHQRE	PLK2	111	Q9NYY3
SIIQHDQPVKPLHRA	UGT2B28	446	Q9BY64
HPVHIAKNIKQQLPV	TERB1	546	Q8NA31
LQDMVPPKKHLLRHQ	TRRAP	1286	Q9Y4A5
VPPRFRHQEHKQLLK	TNRC6A	136	Q8NDV7
KLEHRIKQPTVKLHG	SPOCK2	116	Q92563
PLVILPQRKFQLHHL	TTF2	831	Q9UNY4
RHKKTHRQVPPQSPL	ZNF296	276	Q8WUU4