Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	DEP	DEPDC5 DEPTOR	6.84e-04	22	33	2	PF00610
Domain	DEP	DEPDC5 DEPTOR	6.84e-04	22	33	2	SM00049
Domain	DEP	DEPDC5 DEPTOR	6.84e-04	22	33	2	PS50186
Domain	DEP_dom	DEPDC5 DEPTOR	7.48e-04	23	33	2	IPR000591
Domain	BROMODOMAIN_1	TRIM66 BAZ2B	1.94e-03	37	33	2	PS00633
Domain	Bromodomain	TRIM66 BAZ2B	2.05e-03	38	33	2	PF00439
Domain	BROMODOMAIN_2	TRIM66 BAZ2B	2.38e-03	41	33	2	PS50014
Domain	BROMO	TRIM66 BAZ2B	2.49e-03	42	33	2	SM00297
Domain	Bromodomain	TRIM66 BAZ2B	2.49e-03	42	33	2	IPR001487
Domain	-	TRIM66 BAZ2B	2.49e-03	42	33	2	1.20.920.10
Domain	PHD	TRIM66 BAZ2B	7.75e-03	75	33	2	PF00628
Domain	Znf_PHD-finger	TRIM66 BAZ2B	8.57e-03	79	33	2	IPR019787
Domain	PHD	TRIM66 BAZ2B	1.08e-02	89	33	2	SM00249
Domain	Znf_PHD	TRIM66 BAZ2B	1.12e-02	91	33	2	IPR001965
Domain	ZF_PHD_2	TRIM66 BAZ2B	1.22e-02	95	33	2	PS50016
Domain	ZF_PHD_1	TRIM66 BAZ2B	1.24e-02	96	33	2	PS01359
Pathway	KEGG_MEDICUS_REFERENCE_GATOR1_MTORC1_SIGNALING_PATHWAY	DEPDC5 DEPTOR	1.90e-04	14	21	2	M47918
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	TRIM66 PTPN23 DMXL2 PLEKHA6 YTHDC1 BAZ2B CASZ1 POP1 PDZRN4	8.23e-10	493	34	9	15368895
Pubmed	SETD1A Methyltransferase Is Physically and Functionally Linked to the DNA Damage Repair Protein RAD18.	MFAP1 DLST ANP32B POP1	1.04e-04	251	34	4	31076518
Pubmed	Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	PTPN23 BAZ2B POGK	1.41e-04	103	34	3	10819331
Pubmed	The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells.	MFAP1 BAZ2B ANP32B POP1	1.62e-04	282	34	4	23667531
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	MFAP1 PRPF8 YTHDC1 BAZ2B CASZ1 GPS2 POP1	2.16e-04	1294	34	7	30804502
Pubmed	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	TRIM66 HHIP COLGALT2	2.74e-04	129	34	3	23563607
Pubmed	NudCL2 regulates cell migration by stabilizing both myosin-9 and LIS1 with Hsp90.	LAMA3 DMXL2 PRPF8 POP1	3.05e-04	333	34	4	32665550
Pubmed	Single-cell transcriptomic landscapes of the otic neuronal lineage at multiple early embryonic ages.	NEUROD1 CASZ1	3.97e-04	30	34	2	35320729
Pubmed	Cryo-EM Structure of a Pre-catalytic Human Spliceosome Primed for Activation.	MFAP1 PRPF8	4.81e-04	33	34	2	28781166
Pubmed	Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations.	PTPN23 MFAP1 YTHDC1 ANP32B PCM1 GPS2 ZNF646	4.82e-04	1477	34	7	31515488
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	MFAP1 DLST DMXL2 PRPF8 ANP32B PCM1 POP1	5.02e-04	1487	34	7	33957083
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	PTPN23 ZNF821 CAMTA2 NEUROD1 KCNJ8 POP1	5.76e-04	1084	34	6	11544199
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	MFAP1 YTHDC1 MAP4K1 PCM1 POP1	8.78e-04	774	34	5	15302935
Cytoband	Ensembl 112 genes in cytogenetic band chr17p13	CAMTA2 PRPF8 GPS2	2.14e-03	346	34	3	chr17p13
GeneFamily	PHD finger proteins	TRIM66 BAZ2B	4.39e-03	90	20	2	88
GeneFamily	PDZ domain containing	DEPTOR PDZRN4	1.21e-02	152	20	2	1220
Disease	primary aldosteronism	DMXL2 CASZ1	4.12e-04	26	34	2	MONDO_0001422
Disease	body weight	TRIM66 HHIP COLGALT2 MON1A TEX46 PCM1 PDZRN4	4.99e-04	1261	34	7	EFO_0004338
Disease	Ischemic stroke	PRPF8 CASZ1 POP1 PDZRN4	5.10e-04	324	34	4	HP_0002140
Disease	total hip arthroplasty, osteoarthritis	HHIP COLGALT2	1.08e-03	42	34	2	EFO_0009806, MONDO_0005178
Disease	Acute Cerebrovascular Accidents	PRPF8 CASZ1	1.78e-03	54	34	2	C0751956
Disease	cocaine dependence	POP1 RASGEF1B	2.05e-03	58	34	2	EFO_0002610
Disease	Cerebrovascular accident	PRPF8 CASZ1	2.33e-03	62	34	2	C0038454
Disease	skin pigmentation	PLEKHA6 PDZRN4	2.88e-03	69	34	2	EFO_0003784
Disease	migraine disorder	DLST CASZ1 PDZRN4	7.96e-03	357	34	3	MONDO_0005277
Disease	sexual dimorphism measurement	PTPN23 HHIP COLGALT2 MON1A RASGEF1B	8.27e-03	1106	34	5	EFO_0021796
Disease	smoking behavior, body mass index	TRIM66 DMXL2	8.86e-03	123	34	2	EFO_0004318, EFO_0004340
Disease	Polyarthritis, Juvenile, Rheumatoid Factor Positive	MTSS1 RASGEF1B	1.00e-02	131	34	2	C4704862
Disease	Polyarthritis, Juvenile, Rheumatoid Factor Negative	MTSS1 RASGEF1B	1.00e-02	131	34	2	C4552091
Disease	Juvenile arthritis	MTSS1 RASGEF1B	1.00e-02	131	34	2	C3495559

Protein segments in the cluster

Peptide	Gene	Start	Entry
ARKHMRRMLGKNFDR	CASZ1	1321	Q86V15
KHQERERRRQHMMLM	BAZ2B	1001	Q9UIF8
RALHRHIMMERERKR	GPS2	16	Q13227
KIMRFLRRCRHRMRE	CAMTA2	1171	O94983
MDMKRRIHLELRNRT	ANP32B	1	Q92688
DIDKHRRRFNMRMLV	DMXL2	2411	Q8TDJ6
VRAKEQRRRREFMMR	PDZRN4	951	Q6ZMN7
RRMRQQRKHMLQEKL	PTPN23	1426	Q9H3S7
IRRRHRSDRMMRKGT	DEPDC5	996	O75140
ERRRGMMRQRAQERK	MFAP1	146	P55081
RKRNSMRRNNSMRRN	KCNJ8	381	Q15842
MMRELRNRNFGKHLR	LAMA3	1976	Q16787
MRRHEMLREELRQRR	PCM1	826	Q15154
RMCMRHRSIEAKLRQ	MTSS1	81	O43312
NLRTAMRRQMRRHAS	LRP3	581	O75074
RRMMRRYDLSLRHKV	POGK	311	Q9P215
RDERMMRNLKDLAHR	RASGEF1B	126	Q0VAM2
SEHREKMNRMRQRIA	DLST	221	P36957
PRHMRRRAMSHNVKR	POP1	136	Q99575
RNRRAQRMATDMQRK	MON1A	91	Q86VX9
QFRMNFRRRRRLMEL	DEPTOR	216	Q8TB45
MINLKRRKDRRDRML	COLGALT2	346	Q8IYK4
NHEMKSAMRRLKRRL	OR4D10	291	Q8NGI6
RRHMEFRKLRGMETR	MAP4K1	336	Q92918
KRLKRRDRRMMSQLE	HHIP	46	Q96QV1
MRREKRDRRHFKRMR	PRPF8	151	Q6P2Q9
DRMRRHQSGSMREKR	PLEKHA6	826	Q9Y2H5
MAAMKNHLRRHSRRR	ZNF646	656	O15015
LQLERKFGRMRRLHM	TSPYL4	226	Q9UJ04
KFGRMRRLHMQRRSF	TSPYL4	231	Q9UJ04
KMRHKRRMHSQPRSR	YTHDC1	506	Q96MU7
REGRLQHGNMRKNMR	nan	296	Q8N9G6
RRMRDREAKRLQRMQ	ZNF821	296	O75541
KRRRRHMENERAKRM	TRIM66	1191	O15016
RHRNFPMKKHRMRRH	TEX46	91	H3BTG2
MTKARKRRRRRRLME	THEG	116	Q9P2T0
LRRMKANARERNRMH	NEUROD1	101	Q13562