Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionsecondary active transmembrane transporter activity

SLC2A9 SLC37A3 SLC16A9 SLCO2B1 SLC6A19 SLCO4A1 SLC26A9 SLCO1B3 SLC24A3 SLCO1B1 SLC5A5 SLC17A5 SLC10A2 SLCO4C1 SLC16A5 SLC16A4 SLC41A3 SLC34A1 SLC18A1 SLCO2A1 SLC5A6 SLC22A4 SLC4A10 SLC16A7 SLC37A4 SLC16A10

8.00e-2329612326GO:0015291
GeneOntologyMolecularFunctionactive transmembrane transporter activity

ATP6V1A SLC2A9 SLC37A3 SLC16A9 SLCO2B1 SLC6A19 SLCO4A1 SLC26A9 SLCO1B3 SLC24A3 SLCO1B1 ABCA9 SLC5A5 SLC17A5 SLC10A2 SLCO4C1 SLC16A5 SLC16A4 SLC41A3 SLC34A1 SLC18A1 SLCO2A1 SLC5A6 SLC22A4 SLC4A10 SLC16A7 SLC37A4 SLC16A10

8.41e-2047712328GO:0022804
GeneOntologyMolecularFunctionorganic anion transmembrane transporter activity

SLC37A3 SLC16A9 SLCO2B1 SLCO4A1 SLC26A9 SLCO1B3 SLCO1B1 SLC17A5 SLC10A2 SLCO4C1 SLC16A5 SLC16A4 SLCO2A1 SLC5A6 SLC4A10 SLC25A29 SLC16A7 SLC37A4 MFSD10 SLC16A10

1.45e-1529312320GO:0008514
GeneOntologyMolecularFunctiontransmembrane transporter activity

ATP6V1A SLC2A9 SLC37A3 SLC16A9 SLCO2B1 SLC6A19 SLCO4A1 SLC26A9 SLCO1B3 SLC24A3 APOL1 SLCO1B1 ABCA9 SLC39A13 SLC2A5 SLC5A5 SLC41A2 SLC17A5 SLC10A2 SLCO4C1 SLC16A5 SLC16A4 SLC41A3 SLC34A1 SLC18A1 SLCO2A1 SLC5A6 SLC22A4 SLC4A10 SLC49A3 SLC25A29 SLC16A7 SLC37A4 MFSD10 SLC16A10

2.52e-15118012335GO:0022857
GeneOntologyMolecularFunctionsymporter activity

SLC2A9 SLC16A9 SLC6A19 SLC24A3 SLC5A5 SLC17A5 SLC10A2 SLC16A5 SLC16A4 SLC34A1 SLC18A1 SLC5A6 SLC22A4 SLC4A10 SLC16A7

2.35e-1415012315GO:0015293
GeneOntologyMolecularFunctiontransporter activity

ATP6V1A SLC2A9 SLC37A3 SLC16A9 SLCO2B1 SLC6A19 SLCO4A1 SLC26A9 SLCO1B3 SLC24A3 APOL1 SLCO1B1 ABCA9 SLC39A13 SLC2A5 SLC5A5 SLC41A2 SLC17A5 SLC10A2 SLCO4C1 SLC16A5 SLC16A4 SLC41A3 SLC34A1 SLC18A1 SLCO2A1 SLC5A6 SLC22A4 SLC4A10 SLC49A3 SLC25A29 SLC16A7 SLC37A4 MFSD10 SLC16A10

3.54e-14128912335GO:0005215
GeneOntologyMolecularFunctionmonocarboxylic acid transmembrane transporter activity

SLC16A9 SLCO2B1 SLCO1B3 SLCO1B1 SLC10A2 SLC16A5 SLC16A4 SLC5A6 SLC16A7 SLC16A10

2.05e-109012310GO:0008028
GeneOntologyMolecularFunctioncarboxylic acid transmembrane transporter activity

SLC16A9 SLCO2B1 SLC26A9 SLCO1B3 SLCO1B1 SLC17A5 SLC10A2 SLC16A5 SLC16A4 SLC5A6 SLC25A29 SLC16A7 SLC16A10

4.94e-1020712313GO:0046943
GeneOntologyMolecularFunctionorganic acid transmembrane transporter activity

SLC16A9 SLCO2B1 SLC26A9 SLCO1B3 SLCO1B1 SLC17A5 SLC10A2 SLC16A5 SLC16A4 SLC5A6 SLC25A29 SLC16A7 SLC16A10

5.25e-1020812313GO:0005342
GeneOntologyMolecularFunctionsodium-independent organic anion transmembrane transporter activity

SLCO2B1 SLCO4A1 SLCO1B3 SLCO1B1 SLCO4C1 SLCO2A1

8.44e-10181236GO:0015347
GeneOntologyMolecularFunctionprostaglandin transmembrane transporter activity

SLCO2B1 SLCO4A1 SLCO1B3 SLCO1B1 SLCO2A1

1.56e-08141235GO:0015132
GeneOntologyMolecularFunctionicosanoid transmembrane transporter activity

SLCO2B1 SLCO4A1 SLCO1B3 SLCO1B1 SLCO2A1

2.34e-08151235GO:0071714
GeneOntologyMolecularFunctionolfactory receptor activity

OR4N2 OR9G1 OR2T27 OR4N4 OR2T7 OR10Q1 OR2T1 OR14I1 OR9G9 OR11H6 OR3A2 OR6F1 OR52A5 OR7D2 OR2H2

6.75e-0843112315GO:0004984
GeneOntologyMolecularFunctionorganic hydroxy compound transmembrane transporter activity

SLCO2B1 SLCO1B3 SLCO1B1 SLC10A2 SLC18A1 SLC16A7 MFSD10

2.46e-07701237GO:1901618
GeneOntologyMolecularFunctionactive monoatomic ion transmembrane transporter activity

ATP6V1A SLC2A9 SLC26A9 SLC24A3 SLC5A5 SLC17A5 SLC10A2 SLC41A3 SLC34A1 SLC18A1 SLC5A6 SLC4A10

3.58e-0730112312GO:0022853
GeneOntologyMolecularFunctionG protein-coupled receptor activity

TBXA2R CMKLR2 OR4N2 OR9G1 OR2T27 OR4N4 OR2T7 OR10Q1 OR2T1 ADGRL1 OR14I1 CCKBR OR9G9 OR11H6 OR3A2 OR6F1 TAS2R9 OR52A5 OR7D2 OR2H2

4.54e-0788412320GO:0004930
GeneOntologyMolecularFunctionsolute:monoatomic cation symporter activity

SLC2A9 SLC5A5 SLC17A5 SLC10A2 SLC34A1 SLC18A1 SLC5A6 SLC4A10

7.30e-071191238GO:0015294
GeneOntologyMolecularFunctioninorganic anion transmembrane transporter activity

SLC37A3 SLC26A9 APOL1 SLC5A5 SLC34A1 SLC18A1 SLC5A6 SLC4A10 SLC37A4

1.14e-061711239GO:0015103
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

TBXA2R CMKLR2 OR4N2 OR9G1 OR2T27 OR4N4 HLA-DQB1 OR2T7 OR10Q1 NRG2 OR2T1 ADGRL1 OR14I1 CCKBR OR9G9 OR11H6 OR3A2 OR6F1 TAS2R9 NRXN1 OR52A5 OR7D2 TLR5 OR2H2

2.25e-06135312324GO:0004888
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

ATP6V1A SLC2A9 SLC37A3 SLC26A9 SLC24A3 APOL1 SLC39A13 SLC5A5 SLC41A2 SLC17A5 SLC10A2 SLC41A3 SLC34A1 SLC18A1 SLC5A6 SLC4A10 SLC37A4

4.08e-0675812317GO:0015318
GeneOntologyMolecularFunctionlipid transmembrane transporter activity

SLCO2B1 SLCO4A1 SLCO1B3 SLCO1B1 SLC10A2 SLCO2A1

5.87e-06731236GO:0170055
GeneOntologyMolecularFunctionsolute:sodium symporter activity

SLC5A5 SLC10A2 SLC34A1 SLC18A1 SLC5A6 SLC4A10

1.08e-05811236GO:0015370
GeneOntologyMolecularFunctionsodium ion transmembrane transporter activity

SLC24A3 SLC5A5 SLC10A2 SLC41A3 SLC34A1 SLC18A1 SLC5A6 SLC4A10

1.10e-051711238GO:0015081
GeneOntologyMolecularFunctionthyroid hormone transmembrane transporter activity

SLCO4A1 SLCO1B1 SLC16A10

1.86e-0591233GO:0015349
GeneOntologyMolecularFunctionantiporter activity

SLC37A3 SLC26A9 SLC24A3 SLC41A3 SLC18A1 SLC4A10 SLC37A4

2.36e-051381237GO:0015297
GeneOntologyMolecularFunctionsolute:inorganic anion antiporter activity

SLC37A3 SLC26A9 SLC4A10 SLC37A4

4.31e-05321234GO:0005452
GeneOntologyMolecularFunctionbile acid transmembrane transporter activity

SLCO2B1 SLCO1B3 SLCO1B1 SLC10A2

5.51e-05341234GO:0015125
GeneOntologyMolecularFunctionquaternary ammonium group transmembrane transporter activity

SLC16A9 SLC22A4 SLC25A29

9.83e-05151233GO:0015651
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

ATP6V1A SLC2A9 SLC26A9 SLC24A3 APOL1 SLC39A13 SLC5A5 SLC41A2 SLC17A5 SLC10A2 SLC41A3 SLC34A1 SLC18A1 SLC5A6 SLC4A10

1.10e-0479312315GO:0015075
GeneOntologyMolecularFunction15-oxoprostaglandin 13-oxidase [NAD(P)+] activity

PTGR2 PTGR1

1.12e-0431232GO:0047522
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

ATP6V1A SLC2A9 SLC24A3 SLC39A13 SLC5A5 SLC41A2 SLC17A5 SLC10A2 SLC41A3 SLC34A1 SLC18A1 SLC5A6 SLC4A10

1.32e-0462712313GO:0022890
GeneOntologyMolecularFunctionsecondary active monocarboxylate transmembrane transporter activity

SLC10A2 SLC5A6 SLC16A7

2.06e-04191233GO:0015355
GeneOntologyMolecularFunctionlipid transporter activity

SLCO2B1 SLCO4A1 SLCO1B3 SLCO1B1 ABCA9 SLC10A2 SLCO2A1

2.15e-041961237GO:0005319
GeneOntologyMolecularFunctionhexose-phosphate:phosphate antiporter activity

SLC37A3 SLC37A4

2.24e-0441232GO:0015526
GeneOntologyMolecularFunctionhexose phosphate transmembrane transporter activity

SLC37A3 SLC37A4

2.24e-0441232GO:0015119
GeneOntologyMolecularFunctionglucose-6-phosphate transmembrane transporter activity

SLC37A3 SLC37A4

2.24e-0441232GO:0015152
GeneOntologyMolecularFunctionadipokinetic hormone receptor activity

CMKLR2 ADIPOR1

2.24e-0441232GO:0097003
GeneOntologyMolecularFunctionglucose 6-phosphate:phosphate antiporter activity

SLC37A3 SLC37A4

2.24e-0441232GO:0061513
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

ATP6V1A SLC2A9 SLC24A3 SLC39A13 SLC5A5 SLC41A2 SLC17A5 SLC10A2 SLC41A3 SLC34A1 SLC18A1 SLC5A6 SLC4A10

2.32e-0466412313GO:0008324
GeneOntologyMolecularFunctionmonoatomic anion transmembrane transporter activity

SLC26A9 APOL1 SLC5A5 SLC18A1 SLC5A6 SLC4A10

3.48e-041511236GO:0008509
GeneOntologyMolecularFunctioniodide transmembrane transporter activity

SLC5A5 SLC5A6

3.72e-0451232GO:0015111
GeneOntologyMolecularFunctionalpha-1,4-glucosidase activity

SI MGAM2

3.72e-0451232GO:0004558
GeneOntologyMolecularFunctionphosphate transmembrane transporter activity

SLC37A3 SLC34A1 SLC37A4

4.20e-04241233GO:0005315
GeneOntologyMolecularFunctioncarnitine transmembrane transporter activity

SLC16A9 SLC22A4

5.55e-0461232GO:0015226
GeneOntologyMolecularFunctionoxidoreductase activity, acting on the CH-CH group of donors

PTGR2 LBR PTGR1 SDHC

5.80e-04621234GO:0016627
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

SLC24A3 SLC39A13 SLC5A5 SLC41A2 SLC10A2 SLC41A3 SLC34A1 SLC18A1 SLC5A6 SLC4A10

6.13e-0446512310GO:0046873
GeneOntologyMolecularFunctiongrowth factor receptor binding

NRG2 TGFA NRXN1 PDCL3 TLR5 FLRT2

7.14e-041731236GO:0070851
GeneOntologyMolecularFunctionorganophosphate:phosphate antiporter activity

SLC37A3 SLC37A4

7.75e-0471232GO:0015315
GeneOntologyMolecularFunctionalpha-glucosidase activity

SI MGAM2

7.75e-0471232GO:0090599
GeneOntologyMolecularFunctioncarbohydrate:proton symporter activity

SLC2A9 SLC17A5

1.03e-0381232GO:0005351
GeneOntologyMolecularFunctionmodified amino acid transmembrane transporter activity

SLC16A9 SLC5A6 SLC22A4

1.09e-03331233GO:0072349
GeneOntologyMolecularFunctionoxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor

PTGR2 LBR PTGR1

1.19e-03341233GO:0016628
GeneOntologyMolecularFunctionfructose transmembrane transporter activity

SLC2A9 SLC2A5

1.32e-0391232GO:0005353
GeneOntologyMolecularFunctionguanylate cyclase activity

NPR2 GUCY2D

1.64e-03101232GO:0004383
GeneOntologyMolecularFunctionorganic cation transmembrane transporter activity

SLC16A9 SLC22A4 SLC25A29 SLC16A10

1.73e-03831234GO:0015101
GeneOntologyMolecularFunctioncarbohydrate transmembrane transporter activity

SLC2A9 SLC2A5 SLC17A5

2.20e-03421233GO:0015144
GeneOntologyMolecularFunctionamide transmembrane transporter activity

SLCO1B3 SLCO1B1 SLC5A6

2.20e-03421233GO:0042887
GeneOntologyMolecularFunctionmetal cation:monoatomic cation antiporter activity

SLC24A3 SLC41A3 SLC4A10

2.35e-03431233GO:0140828
GeneOntologyMolecularFunctionchloride:bicarbonate antiporter activity

SLC26A9 SLC4A10

2.81e-03131232GO:0140900
GeneOntologyMolecularFunctionbicarbonate:monoatomic anion antiporter activity

SLC26A9 SLC4A10

2.81e-03131232GO:0140829
GeneOntologyMolecularFunctionmonocarboxylate:sodium symporter activity

SLC10A2 SLC5A6

3.75e-03151232GO:0140161
GeneOntologyMolecularFunctionglucosidase activity

SI MGAM2

3.75e-03151232GO:0015926
GeneOntologyMolecularFunctionhormone binding

CMKLR2 NPR2 CCKBR ADIPOR1

3.79e-031031234GO:0042562
GeneOntologyMolecularFunctionamino acid transmembrane transporter activity

SLC6A19 SLC22A4 SLC25A29 SLC16A10

4.06e-031051234GO:0015171
GeneOntologyMolecularFunctionoligopeptide transmembrane transporter activity

SLCO1B3 SLCO1B1

4.27e-03161232GO:0035673
GeneOntologyMolecularFunctionpeptide hormone binding

CMKLR2 NPR2 CCKBR

4.74e-03551233GO:0017046
GeneOntologyMolecularFunctioncarbohydrate:monoatomic cation symporter activity

SLC2A9 SLC17A5

4.82e-03171232GO:0005402
GeneOntologyMolecularFunctionadenylate cyclase activity

NPR2 GUCY2D

5.40e-03181232GO:0004016
GeneOntologyMolecularFunctionmagnesium ion transmembrane transporter activity

SLC41A2 SLC41A3

5.40e-03181232GO:0015095
GeneOntologyMolecularFunctiontoxic substance binding

DSG1 ADGRL1

5.40e-03181232GO:0015643
GeneOntologyMolecularFunctioncarbohydrate derivative transmembrane transporter activity

SLC37A3 SLC17A5 SLC37A4

5.77e-03591233GO:1901505
GeneOntologyMolecularFunctionmonoatomic anion:sodium symporter activity

SLC5A5 SLC18A1

6.01e-03191232GO:0015373
GeneOntologyMolecularFunctionchloride transmembrane transporter activity

SLC26A9 APOL1 SLC18A1 SLC4A10

7.49e-031251234GO:0015108
GeneOntologyBiologicalProcessorganic anion transport

SLC2A9 SLC37A3 SLC16A9 SLCO2B1 ARL6IP5 SLCO4A1 SLC26A9 SLCO1B3 SLCO1B1 PTGS2 SLC17A5 SLC10A2 SLCO4C1 SLC16A5 SLC16A4 SLCO2A1 SLC5A6 SLC4A10 PLA2G4A SLC25A29 SLC16A7 SLC37A4 MFSD10 SLC16A10

5.21e-1551512424GO:0015711
GeneOntologyBiologicalProcesssodium-independent organic anion transport

SLCO2B1 SLCO4A1 SLCO1B3 SLCO1B1 SLCO4C1 SLCO2A1 MFSD10

1.48e-12151247GO:0043252
GeneOntologyBiologicalProcessmonocarboxylic acid transport

SLC16A9 SLCO2B1 SLCO4A1 SLCO1B3 SLCO1B1 PTGS2 SLC17A5 SLC10A2 SLC16A5 SLC16A4 SLCO2A1 SLC5A6 PLA2G4A SLC16A7 SLC16A10

2.92e-1221312415GO:0015718
GeneOntologyBiologicalProcesscarboxylic acid transport

SLC16A9 SLCO2B1 ARL6IP5 SLCO4A1 SLC26A9 SLCO1B3 SLCO1B1 PTGS2 SLC17A5 SLC10A2 SLC16A5 SLC16A4 SLCO2A1 SLC5A6 PLA2G4A SLC25A29 SLC16A7 SLC16A10

4.84e-1141012418GO:0046942
GeneOntologyBiologicalProcessorganic acid transport

SLC16A9 SLCO2B1 ARL6IP5 SLCO4A1 SLC26A9 SLCO1B3 SLCO1B1 PTGS2 SLC17A5 SLC10A2 SLC16A5 SLC16A4 SLCO2A1 SLC5A6 PLA2G4A SLC25A29 SLC16A7 SLC16A10

5.24e-1141212418GO:0015849
GeneOntologyBiologicalProcessdetection of chemical stimulus involved in sensory perception

OR4N2 OR9G1 OR2T27 OR4N4 OR2T7 OR10Q1 OR2T1 OR14I1 OR9G9 OR11H6 OR3A2 OR6F1 TAS2R9 OR52A5 OR7D2 OR2H2

3.60e-0848512416GO:0050907
GeneOntologyBiologicalProcessprostaglandin transport

SLCO2B1 SLCO4A1 SLCO1B1 PTGS2 SLCO2A1 PLA2G4A

4.90e-08341246GO:0015732
GeneOntologyBiologicalProcessdetection of chemical stimulus involved in sensory perception of smell

OR4N2 OR9G1 OR2T27 OR4N4 OR2T7 OR10Q1 OR2T1 OR14I1 OR9G9 OR11H6 OR3A2 OR6F1 OR52A5 OR7D2 OR2H2

5.11e-0843212415GO:0050911
GeneOntologyBiologicalProcessdetection of chemical stimulus

OR4N2 OR9G1 OR2T27 OR4N4 OR2T7 OR10Q1 OR2T1 OR14I1 OR9G9 OR11H6 OR3A2 OR6F1 TAS2R9 OR52A5 OR7D2 OR2H2

1.04e-0752412416GO:0009593
GeneOntologyBiologicalProcesssensory perception of smell

OR4N2 OR9G1 OR2T27 OR4N4 OR2T7 OR10Q1 OR2T1 OR14I1 OR9G9 OR11H6 OR3A2 OR6F1 OR52A5 OR7D2 OR2H2

1.33e-0746512415GO:0007608
GeneOntologyBiologicalProcesssensory perception of chemical stimulus

OR4N2 OR9G1 OR2T27 OR4N4 OR2T7 OR10Q1 OR2T1 OR14I1 OR9G9 OR11H6 OR3A2 OR6F1 TAS2R9 OR52A5 OR7D2 OR2H2

1.86e-0754712416GO:0007606
GeneOntologyBiologicalProcessdetection of stimulus involved in sensory perception

OR4N2 OR9G1 OR2T27 OR4N4 OR2T7 OR10Q1 OR2T1 OR14I1 OR9G9 OR11H6 OR3A2 OR6F1 TAS2R9 OR52A5 OR7D2 OR2H2

4.28e-0758212416GO:0050906
GeneOntologyBiologicalProcessdetection of stimulus

OR4N2 OR9G1 OR2T27 OR4N4 OR2T7 OR10Q1 OR2T1 OR14I1 OR9G9 OR11H6 OR3A2 OR6F1 TAS2R9 OR52A5 OR7D2 GUCY2D OR2H2

1.54e-0672212417GO:0051606
GeneOntologyBiologicalProcessmonoatomic ion transport

ATP6V1A SLC2A9 ANK2 SLCO2B1 SLC6A19 SLCO4A1 SLC26A9 SLCO1B3 SLC24A3 APOL1 SLCO1B1 PTGS2 SLC39A13 SLC5A5 SLC41A2 SLC17A5 SLC10A2 SLCO4C1 SLC41A3 SLC34A1 SLC18A1 SLC5A6 SLC22A4 SLC4A10

1.95e-06137412424GO:0006811
GeneOntologyBiologicalProcessicosanoid transport

SLCO2B1 SLCO4A1 SLCO1B1 PTGS2 SLCO2A1 PLA2G4A

5.12e-06731246GO:0071715
GeneOntologyBiologicalProcesssensory perception

NPR2 OR4N2 OR9G1 OR2T27 OR4N4 OR2T7 OR10Q1 OR2T1 OR14I1 OR9G9 OR11H6 OR3A2 OR6F1 TAS2R9 OR52A5 OR7D2 GUCY2D SLC4A10 MYO15A OR2H2

6.03e-06107212420GO:0007600
GeneOntologyBiologicalProcessinorganic anion transport

SLC37A3 SLC26A9 APOL1 SLC5A5 SLC34A1 SLC5A6 SLC4A10 SLC37A4

1.34e-051801248GO:0015698
GeneOntologyBiologicalProcessinorganic anion transmembrane transport

SLC37A3 SLC26A9 APOL1 SLC5A5 SLC34A1 SLC5A6 SLC37A4

1.67e-051341247GO:0098661
GeneOntologyBiologicalProcesscarnitine transport

SLC16A9 SLC22A4 SLC25A29

1.74e-0591243GO:0015879
GeneOntologyBiologicalProcessG protein-coupled receptor signaling pathway

TBXA2R CMKLR2 OR4N2 OR9G1 OR2T27 OR4N4 OR2T7 OR10Q1 OR2T1 ADGRL1 OR14I1 CCKBR OR9G9 OR11H6 OR3A2 OR6F1 DEFB4A TAS2R9 OR52A5 OR7D2 GUCY2D OR2H2

2.75e-05139512422GO:0007186
GeneOntologyBiologicalProcesspigment catabolic process

SLCO2B1 SLCO1B3 SLCO1B1

3.38e-05111243GO:0046149
GeneOntologyBiologicalProcessheme catabolic process

SLCO2B1 SLCO1B3 SLCO1B1

3.38e-05111243GO:0042167
GeneOntologyBiologicalProcessinorganic ion transmembrane transport

ATP6V1A SLC2A9 SLC37A3 ANK2 SLC6A19 SLC26A9 SLC24A3 APOL1 SLC39A13 SLC5A5 SLC41A2 SLC17A5 SLC41A3 SLC34A1 SLC18A1 SLC5A6 SLC4A10 SLC37A4

3.72e-05101712418GO:0098660
GeneOntologyBiologicalProcesssodium ion transport

SLC6A19 SLC24A3 SLC5A5 SLC10A2 SLC41A3 SLC34A1 SLC5A6 SLC22A4 SLC4A10

4.36e-052751249GO:0006814
GeneOntologyBiologicalProcessthyroid hormone transport

SLCO4A1 SLCO1B1 SLC16A10

5.80e-05131243GO:0070327
GeneOntologyBiologicalProcessporphyrin-containing compound catabolic process

SLCO2B1 SLCO1B3 SLCO1B1

5.80e-05131243GO:0006787
GeneOntologyBiologicalProcesstetrapyrrole catabolic process

SLCO2B1 SLCO1B3 SLCO1B1

7.35e-05141243GO:0033015
GeneOntologyBiologicalProcessamino-acid betaine transport

SLC16A9 SLC22A4 SLC25A29

7.35e-05141243GO:0015838
GeneOntologyBiologicalProcessphosphate ion transmembrane transport

SLC37A3 SLC34A1 SLC37A4

9.15e-05151243GO:0035435
GeneOntologyBiologicalProcessiodide transmembrane transport

SLC5A5 SLC5A6

1.07e-0431242GO:1904200
GeneOntologyBiologicalProcessmodified amino acid transport

SLC16A9 SLC5A6 SLC22A4 SLC25A29

1.40e-04441244GO:0072337
GeneOntologyBiologicalProcessfatty acid transport

SLCO2B1 SLCO4A1 SLCO1B1 PTGS2 SLCO2A1 PLA2G4A

1.48e-041321246GO:0015908
GeneOntologyBiologicalProcesstransport across blood-brain barrier

SLCO2B1 SLC24A3 SLC5A5 SLC5A6 SLC16A7

1.80e-04871245GO:0150104
GeneOntologyBiologicalProcessbile acid and bile salt transport

SLCO2B1 SLCO1B3 SLCO1B1 SLC10A2

1.82e-04471244GO:0015721
GeneOntologyBiologicalProcessvascular transport

SLCO2B1 SLC24A3 SLC5A5 SLC5A6 SLC16A7

1.90e-04881245GO:0010232
GeneOntologyBiologicalProcessquaternary ammonium group transport

SLC16A9 SLC22A4 SLC25A29

1.92e-04191243GO:0015697
GeneOntologyBiologicalProcesslipid transport

SLCO2B1 SLCO4A1 SLCO1B3 APOL1 SLCO1B1 ABCA9 PTGS2 SLC10A2 SLCO2A1 PLA2G4A SOAT1

2.43e-0450612411GO:0006869
GeneOntologyBiologicalProcesssodium ion transmembrane transport

SLC6A19 SLC24A3 SLC5A5 SLC41A3 SLC34A1 SLC5A6 SLC4A10

2.66e-042081247GO:0035725
GeneOntologyBiologicalProcessprostaglandin metabolic process

PTGR2 PTGS2 PTGR1 PLA2G4A

3.59e-04561244GO:0006693
GeneOntologyBiologicalProcessprostanoid metabolic process

PTGR2 PTGS2 PTGR1 PLA2G4A

3.84e-04571244GO:0006692
GeneOntologyBiologicalProcesscarboxylic acid transmembrane transport

SLC16A9 ARL6IP5 SLC17A5 SLC5A6 SLC25A29 SLC16A7

4.60e-041631246GO:1905039
GeneOntologyBiologicalProcessorganic acid transmembrane transport

SLC16A9 ARL6IP5 SLC17A5 SLC5A6 SLC25A29 SLC16A7

5.23e-041671246GO:1903825
GeneOntologyBiologicalProcessmonoatomic cation transport

ATP6V1A SLC2A9 ANK2 SLC6A19 SLC24A3 PTGS2 SLC39A13 SLC5A5 SLC41A2 SLC17A5 SLC10A2 SLC41A3 SLC34A1 SLC18A1 SLC5A6 SLC22A4 SLC4A10

5.63e-04115712417GO:0006812
GeneOntologyBiologicalProcesslipid localization

SLCO2B1 SLCO4A1 SLCO1B3 APOL1 SLCO1B1 ABCA9 PTGS2 SLC10A2 SLCO2A1 PLA2G4A SOAT1

6.13e-0456512411GO:0010876
GeneOntologyBiologicalProcesshexose phosphate transport

SLC37A3 SLC37A4

7.38e-0471242GO:0015712
GeneOntologyBiologicalProcessglucose-6-phosphate transport

SLC37A3 SLC37A4

7.38e-0471242GO:0015760
GeneOntologyBiologicalProcesscarnitine transmembrane transport

SLC16A9 SLC22A4

7.38e-0471242GO:1902603
GeneOntologyBiologicalProcessamino acid transmembrane transport

ARL6IP5 SLC6A19 SLC22A4 SLC25A29 SLC16A10

7.95e-041201245GO:0003333
GeneOntologyBiologicalProcessphosphate ion transport

SLC37A3 SLC34A1 SLC37A4

8.43e-04311243GO:0006817
GeneOntologyBiologicalProcessregulation of synapse maturation

NRG2 ADGRL1 NRXN1

8.43e-04311243GO:0090128
GeneOntologyBiologicalProcessmonoatomic anion transport

SLC26A9 APOL1 SLC5A5 SLC17A5 SLC5A6 SLC4A10

8.45e-041831246GO:0006820
GeneOntologyBiologicalProcessmonoatomic ion transmembrane transport

ATP6V1A SLC2A9 ANK2 SLC6A19 SLC26A9 SLC24A3 APOL1 SLC39A13 SLC5A5 SLC41A2 SLC17A5 SLC41A3 SLC34A1 SLC18A1 SLC5A6 SLC4A10

1.06e-03111512416GO:0034220
GeneOntologyBiologicalProcessthyroid hormone metabolic process

SLCO4A1 SLC5A5 SLC16A10

1.11e-03341243GO:0042403
GeneOntologyCellularComponentbasal plasma membrane

SLC2A9 ANK2 SLCO2B1 SLCO4A1 SLCO1B3 SLCO1B1 TGFA SLC17A5 SLCO4C1 SLC16A5 SLC34A1 SLCO2A1 SLC5A6 SLC22A4 SLC4A10 SLC16A7 SLC16A10

3.53e-1135412417GO:0009925
GeneOntologyCellularComponentbasolateral plasma membrane

SLC2A9 ANK2 SLCO2B1 SLCO4A1 SLCO1B3 SLCO1B1 TGFA SLC17A5 SLCO4C1 SLC16A5 SLC34A1 SLCO2A1 SLC5A6 SLC4A10 SLC16A7 SLC16A10

7.66e-1132012416GO:0016323
GeneOntologyCellularComponentbasal part of cell

SLC2A9 ANK2 SLCO2B1 SLCO4A1 SLCO1B3 SLCO1B1 TGFA SLC17A5 SLCO4C1 SLC16A5 SLC34A1 SLCO2A1 SLC5A6 SLC22A4 SLC4A10 SLC16A7 SLC16A10

9.80e-1137812417GO:0045178
GeneOntologyCellularComponentapical plasma membrane

ATP6V1A SLC2A9 ANK2 DSG1 SLCO2B1 SLC6A19 SLC26A9 SI SLC2A5 SLC10A2 SLC34A1 SLC5A6 SLC22A4 PKHD1 SLC4A10

2.03e-0748712415GO:0016324
GeneOntologyCellularComponentapical part of cell

ATP6V1A SLC2A9 ANK2 DSG1 SLCO2B1 SLC6A19 SLC26A9 SI SLC2A5 SLC10A2 SLC34A1 SLC5A6 SLC22A4 PKHD1 SLC4A10

2.35e-0659212415GO:0045177
HumanPhenoHyperbilirubinemia

SLCO1B3 LBR SLCO1B1 SLC5A5 ADK SLC17A5 HSD3B7 PKHD1

2.32e-05130488HP:0002904
HumanPhenoConjugated hyperbilirubinemia

SLCO1B3 SLCO1B1 SLC17A5 HSD3B7 PKHD1

2.39e-0538485HP:0002908
HumanPhenoAbnormal circulating bilirubin concentration

SLCO1B3 LBR SLCO1B1 SLC5A5 ADK SLC17A5 HSD3B7 PKHD1

2.45e-05131488HP:0033479
HumanPhenoConjunctival icterus

SLCO1B3 SLCO1B1 PKHD1

2.68e-057483HP:0032106
HumanPhenoFat malabsorption

HLA-DQB1 SLC26A9 LBR HSD3B7 SLC10A2 PKHD1

4.22e-0570486HP:0002630
HumanPhenoMalabsorption

DSG1 HLA-DQB1 SLC6A19 SLC26A9 SI LBR HSD3B7 SLC10A2 SLCO2A1 PKHD1

5.01e-052354810HP:0002024
HumanPhenoBilirubinuria

SLCO1B3 SLCO1B1

8.70e-052482HP:0031811
DomainMFS_dom

SLC2A9 SLC37A3 SLC16A9 SLCO2B1 MFSD11 SLCO4A1 SLCO1B3 SLCO1B1 SLC2A5 SLC17A5 SLCO4C1 SLC16A5 SLC16A4 SLC18A1 SLCO2A1 SLC22A4 SLC49A3 SLC16A7 SLC37A4 MFSD10 SLC16A10

1.72e-2313412121IPR020846
DomainMFS

SLC2A9 SLC37A3 SLC16A9 SLCO4A1 SLCO1B3 SLCO1B1 SLC2A5 SLC17A5 SLCO4C1 SLC16A5 SLC16A4 SLC18A1 SLCO2A1 SLC22A4 SLC49A3 SLC16A7 SLC37A4 MFSD10 SLC16A10

2.47e-2210812119PS50850
DomainMFS_1

SLC37A3 SLC16A9 SLC17A5 SLC16A5 SLC16A4 SLC18A1 SLC22A4 SLC49A3 SLC16A7 SLC37A4 MFSD10 SLC16A10

8.07e-147712112PF07690
DomainMFS

SLC37A3 SLC16A9 SLC17A5 SLC16A5 SLC16A4 SLC18A1 SLC22A4 SLC49A3 SLC16A7 SLC37A4 MFSD10 SLC16A10

8.07e-147712112IPR011701
DomainOA_transporter

SLCO2B1 SLCO4A1 SLCO1B3 SLCO1B1 SLCO4C1 SLCO2A1

5.84e-11121216IPR004156
DomainOATP

SLCO2B1 SLCO4A1 SLCO1B3 SLCO1B1 SLCO4C1 SLCO2A1

5.84e-11121216PF03137
DomainOlfact_rcpt

OR4N2 OR9G1 OR2T27 OR4N4 OR10Q1 OR2T1 OR14I1 OR9G9 OR11H6 OR3A2 OR6F1 OR52A5 OR7D2 OR2H2

2.60e-0739312114IPR000725
DomainGPCR_Rhodpsn_7TM

TBXA2R CMKLR2 OR4N2 OR9G1 OR2T27 OR4N4 OR10Q1 OR2T1 OR14I1 CCKBR OR9G9 OR11H6 OR3A2 OR6F1 TAS2R9 OR52A5 OR7D2 OR2H2

3.12e-0767012118IPR017452
DomainG_PROTEIN_RECEP_F1_2

TBXA2R CMKLR2 OR4N2 OR9G1 OR2T27 OR4N4 OR10Q1 OR2T1 OR14I1 CCKBR OR9G9 OR11H6 OR3A2 OR6F1 TAS2R9 OR52A5 OR7D2 OR2H2

4.89e-0769112118PS50262
DomainGPCR_Rhodpsn

TBXA2R CMKLR2 OR4N2 OR9G1 OR2T27 OR4N4 OR10Q1 OR2T1 OR14I1 CCKBR OR9G9 OR11H6 OR3A2 OR6F1 TAS2R9 OR52A5 OR7D2 OR2H2

4.99e-0769212118IPR000276
DomainKAZAL_2

SLCO2B1 SLCO4A1 SLCO1B3 SLCO1B1 SLCO4C1 SLCO2A1

8.22e-07501216PS51465
DomainKazal_dom

SLCO2B1 SLCO4A1 SLCO1B3 SLCO1B1 SLCO4C1 SLCO2A1

9.26e-07511216IPR002350
Domain7tm_1

TBXA2R CMKLR2 OR4N2 OR9G1 OR2T27 OR4N4 OR10Q1 OR2T1 OR14I1 CCKBR OR9G9 OR11H6 OR3A2 OR6F1 OR52A5 OR7D2 OR2H2

1.73e-0667712117PF00001
DomainG_PROTEIN_RECEP_F1_1

TBXA2R CMKLR2 OR4N2 OR9G1 OR2T27 OR4N4 OR10Q1 OR2T1 OR14I1 CCKBR OR9G9 OR11H6 OR3A2 OR6F1 OR52A5 OR7D2 OR2H2

2.03e-0668512117PS00237
DomainKazal_2

SLCO4A1 SLCO1B3 SLCO1B1 SLCO4C1 SLCO2A1

3.37e-06361215PF07648
Domain-

SLC41A2 SLC41A3

1.24e-04312121.10.357.20
DomainMgtE

SLC41A2 SLC41A3

1.24e-0431212PF01769
DomainDUF2371_TMEM200

TMEM200B TMEM200C

1.24e-0431212IPR018787
DomainSLC41_membr_dom

SLC41A2 SLC41A3

1.24e-0431212IPR006667
DomainDUF2371

TMEM200B TMEM200C

1.24e-0431212PF10177
DomainKAZAL

SLCO4A1 SLCO1B3 SLCO1B1 SLCO2A1

2.22e-04461214SM00280
DomainSugar_P_transporter

SLC37A3 SLC37A4

2.48e-0441212IPR000849
DomainNtCtMGAM_N

SI MGAM2

2.48e-0441212PF16863
DomainGal_mutarotase_N

SI MGAM2

2.48e-0441212IPR031727
DomainMCT

SLC16A5 SLC16A7

4.11e-0451212IPR004743
DomainSUGAR_TRANSPORT_1

SLC2A9 SLC2A5 SLC22A4

4.86e-04241213PS00216
DomainGlyco_hydro_31_AS

SI MGAM2

6.14e-0461212IPR030458
DomainEGF_3

HYAL1 VASN NRG2 PTGS2 TGFA HHIP NRXN1

8.56e-042351217PS50026
DomainEGF

HYAL1 VASN NRG2 PTGS2 TGFA HHIP NRXN1

8.56e-042351217SM00181
DomainGlyco_hydro_31

SI MGAM2

8.56e-0471212IPR000322
DomainGlyco_hydro_31

SI MGAM2

8.56e-0471212PF01055
DomainGLYCOSYL_HYDROL_F31_1

SI MGAM2

8.56e-0471212PS00129
DomainNa/solute_symporter_CS

SLC5A5 SLC5A6

1.14e-0381212IPR018212
DomainTrefoil

SI MGAM2

1.14e-0381212PF00088
DomainSugar_transporter_CS

SLC2A9 SLC2A5 SLC22A4

1.15e-03321213IPR005829
DomainLRRCT

VASN TLR5 FLRT2

1.15e-03321213PF01463
DomainEGF-like_dom

HYAL1 VASN NRG2 PTGS2 TGFA HHIP NRXN1

1.20e-032491217IPR000742
DomainEGF_1

HYAL1 VASN NRG2 PTGS2 TGFA HHIP NRXN1

1.37e-032551217PS00022
DomainEGF

VASN NRG2 PTGS2 TGFA NRXN1

1.37e-031261215PF00008
DomainP_TREFOIL_2

SI MGAM2

1.45e-0391212PS51448
DomainPD

SI MGAM2

1.45e-0391212SM00018
DomainEGF-like_CS

HYAL1 VASN NRG2 PTGS2 TGFA HHIP NRXN1

1.57e-032611217IPR013032
DomainMFS_sugar_transport-like

SLC2A9 SLC2A5 SLC22A4

1.62e-03361213IPR005828
DomainSugar_tr

SLC2A9 SLC2A5 SLC22A4

1.62e-03361213PF00083
DomainEGF_2

HYAL1 VASN NRG2 PTGS2 TGFA HHIP NRXN1

1.71e-032651217PS01186
Domain-

SI MGAM2

2.20e-031112124.10.110.10
DomainNA_SOLUT_SYMP_1

SLC5A5 SLC5A6

2.20e-03111212PS00456
DomainNA_SOLUT_SYMP_2

SLC5A5 SLC5A6

2.63e-03121212PS00457
DomainSSF

SLC5A5 SLC5A6

2.63e-03121212PF00474
DomainNa/solute_symporter

SLC5A5 SLC5A6

2.63e-03121212IPR001734
DomainP_trefoil_dom

SI MGAM2

2.63e-03121212IPR000519
DomainNA_SOLUT_SYMP_3

SLC5A5 SLC5A6

2.63e-03121212PS50283
DomainSugar/inositol_transpt

SLC2A9 SLC2A5

3.60e-03141212IPR003663
DomainGlycoside_hydrolase_SF

HYAL1 SI MGAM2

4.91e-03531213IPR017853
DomainGal_mutarotase_SF_dom

SI MGAM2

5.31e-03171212IPR011013
DomainSUGAR_TRANSPORT_2

SLC2A9 SLC2A5

5.31e-03171212PS00217
DomainA/G_cyclase_CS

NPR2 GUCY2D

5.31e-03171212IPR018297
Domain-

PTGR2 PTGR1

5.95e-031812123.90.180.10
DomainNucleotide_cyclase

NPR2 GUCY2D

5.95e-03181212IPR029787
Domain-

NPR2 GUCY2D

5.95e-031812123.30.70.1230
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLC2A9 SLCO2B1 SLC6A19 SLCO4A1 SLC26A9 SLCO1B3 SLC24A3 SLCO1B1 SLC5A5 SLC41A2 SLC17A5 SLCO4C1 SLC34A1 SLC18A1 SLCO2A1 SLC5A6 SLC22A4 SLC4A10 SLC25A29 SLC16A7 SLC16A10

9.91e-182389821MM15076
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLC2A9 SLCO2B1 SLC6A19 SLCO4A1 SLC26A9 SLCO1B3 SLC24A3 SLCO1B1 SLC5A5 SLC41A2 SLC17A5 SLCO4C1 SLC34A1 SLC18A1 SLCO2A1 SLC5A6 SLC22A4 SLC4A10 SLC25A29 SLC16A7 SLC16A10

2.52e-172499821M5988
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

ATP6V1A SLC2A9 SLCO2B1 SLC6A19 SLCO4A1 SLC26A9 SLCO1B3 SLC24A3 SLCO1B1 ABCA9 SLC5A5 SLC41A2 SLC17A5 SLCO4C1 SLC34A1 SLC18A1 SLCO2A1 SLC5A6 SLC22A4 SLC4A10 SLC25A29 SLC16A7 SOAT1 SLC16A10

2.73e-116819824MM14985
PathwayREACTOME_TRANSPORT_OF_ORGANIC_ANIONS

SLCO2B1 SLCO4A1 SLCO1B3 SLCO1B1 SLCO4C1 SLCO2A1

4.34e-1111986M930
PathwayREACTOME_TRANSPORT_OF_ORGANIC_ANIONS

SLCO2B1 SLCO4A1 SLCO1B3 SLCO1B1 SLCO4C1 SLCO2A1

8.64e-1112986MM15476
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

ATP6V1A SLC2A9 SLCO2B1 SLC6A19 SLCO4A1 SLC26A9 SLCO1B3 SLC24A3 SLCO1B1 ABCA9 SLC5A5 SLC41A2 SLC17A5 SLCO4C1 SLC34A1 SLC18A1 SLCO2A1 SLC5A6 SLC22A4 SLC4A10 SLC25A29 SLC16A7 SOAT1 SLC16A10

1.36e-107369824M27287
PathwayREACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES

SLCO2B1 SLCO4A1 SLCO1B3 SLCO1B1 SLCO4C1 SLCO2A1 SLC5A6

1.17e-0841987MM15075
PathwayREACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES

SLCO2B1 SLCO4A1 SLCO1B3 SLCO1B1 SLCO4C1 SLCO2A1 SLC5A6

1.66e-0843987M881
PathwayREACTOME_SLC_TRANSPORTER_DISORDERS

TPR SLC2A9 SLC6A19 SLCO1B3 SLCO1B1 SLC5A5 SLC17A5 SLC34A1 SLCO2A1

2.70e-0899989M27474
PathwayWP_SULFATASE_AND_AROMATASE_PATHWAY

SLCO2B1 SLCO4A1 SLCO1B3 SLCO1B1 SLCO4C1

2.79e-0814985M48085
PathwayREACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES

SLC6A19 SLC26A9 SLC24A3 SLC5A5 SLC17A5 SLC34A1 SLC4A10 SLC25A29 SLC16A10

5.79e-08108989M823
PathwayREACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES

SLC6A19 SLC26A9 SLC24A3 SLC5A5 SLC17A5 SLC34A1 SLC4A10 SLC25A29 SLC16A10

6.28e-08109989MM15074
PathwayREACTOME_OLFACTORY_SIGNALING_PATHWAY

OR4N2 OR9G1 OR2T27 OR4N4 OR2T7 OR10Q1 OR2T1 OR14I1 OR9G9 OR11H6 OR3A2 OR6F1 OR52A5 OR7D2 OR2H2

1.75e-074179815M4072
PathwayKEGG_OLFACTORY_TRANSDUCTION

OR4N2 OR9G1 OR2T27 OR4N4 OR10Q1 OR2T1 OR14I1 OR11H6 OR3A2 OR6F1 OR52A5 OR7D2 GUCY2D OR2H2

4.67e-073899814M14091
PathwayREACTOME_SENSORY_PERCEPTION

OR4N2 OR9G1 OR2T27 OR4N4 OR2T7 OR10Q1 OR2T1 OR14I1 OR9G9 OR11H6 OR3A2 OR6F1 OR52A5 OR7D2 GUCY2D MYO15A OR2H2

1.61e-066369817M41834
PathwayWP_EICOSANOID_METABOLISM_VIA_CYCLOOXYGENASES_COX

TBXA2R PTGR2 PTGS2 PTGR1 PLA2G4A

2.16e-0631985M39851
PathwayWP_EICOSANOID_METABOLISM_VIA_CYCLOOXYGENASES_COX

TBXA2R PTGR2 PTGS2 PTGR1 PLA2G4A

2.98e-0633985MM15918
PathwayREACTOME_DISORDERS_OF_TRANSMEMBRANE_TRANSPORTERS

TPR SLC2A9 SLC6A19 SLCO1B3 SLCO1B1 SLC5A5 SLC17A5 SLC34A1 SLCO2A1

3.82e-06177989M27476
PathwayWP_NRF2_PATHWAY

SLC2A9 SLC6A19 SLC39A13 SLC2A5 TGFA SLC5A5 PTGR1 SLC5A6

6.05e-06141988M39454
PathwayWP_NUCLEAR_RECEPTORS_METAPATHWAY

SLC2A9 SLCO2B1 SLC6A19 SLCO1B1 PTGS2 SLC39A13 SLC2A5 TGFA SLC5A5 PTGR1 SLC5A6

1.12e-053149811M39428
PathwayREACTOME_ATORVASTATIN_ADME

SLCO2B1 SLCO1B3 SLCO1B1

2.65e-059983M45020
PathwayWP_DISORDERS_OF_BILE_ACID_SYNTHESIS_AND_BILIARY_TRANSPORT

SLCO1B3 SLCO1B1 HSD3B7 SLC10A2

4.56e-0529984M45551
PathwayWP_OMEGA6FATTY_ACIDS_IN_SENESCENCE

TBXA2R PTGR2 PTGS2 SLCO2A1 PLA2G4A

4.61e-0557985M48332
PathwayWP_PROXIMAL_TUBULE_TRANSPORT

ATP6V1A SLC6A19 SLC5A5 SLC34A1 SLC16A10

4.61e-0557985M39812
PathwayWP_ENTEROHEPATIC_CIRCULATION_OF_BILE_ACIDS

SLCO1B3 SLCO1B1 SLC10A2

6.85e-0512983M48096
PathwayREACTOME_HEME_DEGRADATION

SLCO2B1 SLCO1B3 SLCO1B1

1.40e-0415983M27060
PathwayREACTOME_ATORVASTATIN_ADME

SLCO2B1 SLCO1B3 SLCO1B1

1.40e-0415983MM15697
PathwayREACTOME_TRANSPORT_OF_BILE_SALTS_AND_ORGANIC_ACIDS_METAL_IONS_AND_AMINE_COMPOUNDS

SLC6A19 SLC41A2 SLC18A1 SLC22A4 SLC16A7

1.83e-0476985MM15072
PathwayREACTOME_BILE_ACID_AND_BILE_SALT_METABOLISM

SLCO1B3 SLCO1B1 HSD3B7 SLC10A2

2.41e-0444984M499
PathwayREACTOME_RECYCLING_OF_BILE_ACIDS_AND_SALTS

SLCO1B3 SLCO1B1 SLC10A2

2.46e-0418983M4862
PathwayREACTOME_BILE_ACID_AND_BILE_SALT_METABOLISM

SLCO1B3 SLCO1B1 HSD3B7 SLC10A2

2.63e-0445984MM14751
PathwayREACTOME_RECYCLING_OF_BILE_ACIDS_AND_SALTS

SLCO1B3 SLCO1B1 SLC10A2

2.91e-0419983MM14612
PathwayREACTOME_TRANSPORT_OF_BILE_SALTS_AND_ORGANIC_ACIDS_METAL_IONS_AND_AMINE_COMPOUNDS

SLC6A19 SLC41A2 SLC18A1 SLC22A4 SLC16A7

2.93e-0484985M27334
PathwayBIOCARTA_EICOSANOID_PATHWAY

TBXA2R PTGS2 PLA2G4A

3.41e-0420983MM1529
PathwayWP_LIPID_METABOLISM_IN_SENESCENT_CELLS

PTGS2 SLCO2A1 PLA2G4A

3.41e-0420983M45542
PathwayREACTOME_HEME_DEGRADATION

SLCO2B1 SLCO1B3 SLCO1B1

3.41e-0420983MM14721
PathwayBIOCARTA_EICOSANOID_PATHWAY

TBXA2R PTGS2 PLA2G4A

4.56e-0422983M22003
PathwayREACTOME_ARACHIDONIC_ACID_METABOLISM

PTGR2 PTGS2 PTGR1 PLA2G4A

7.46e-0459984M27140
PathwayREACTOME_METABOLISM_OF_PORPHYRINS

SLCO2B1 SLCO1B3 SLCO1B1

8.44e-0427983M1088
PathwayREACTOME_METABOLISM_OF_PORPHYRINS

SLCO2B1 SLCO1B3 SLCO1B1

1.40e-0332983MM14719
PathwayREACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE

SLC6A19 SLC25A29 SLC16A10

1.40e-0332983MM14957
PathwayREACTOME_OLFACTORY_SIGNALING_PATHWAY

OR9G1 OR2T1 OR11H6 OR6F1

1.42e-0370984MM14984
PathwayREACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE

SLC6A19 SLC25A29 SLC16A10

1.53e-0333983M188
PathwayREACTOME_DISEASES_OF_CARBOHYDRATE_METABOLISM

HYAL1 SI SLC37A4

1.67e-0334983M27546
PathwayREACTOME_METABOLISM_OF_STEROIDS

SLCO1B3 LBR SLCO1B1 HSD3B7 SLC10A2

1.84e-03126985MM15553
PathwayWP_EICOSANOID_LIPID_SYNTHESIS_MAP

PTGS2 PLA2G4A

2.08e-0310982MM15916
Pubmed

Organic anion transporting polypeptides of the OATP/ SLC21 family: phylogenetic classification as OATP/ SLCO superfamily, new nomenclature and molecular/functional properties.

SLCO2B1 SLCO4A1 SLCO1B3 SLCO1B1 SLCO4C1 SLCO2A1

8.69e-1311125614579113
Pubmed

Mechanisms of pH-gradient driven transport mediated by organic anion polypeptide transporters.

SLCO2B1 SLCO4A1 SLCO1B3 SLCO1B1 SLCO4C1

3.07e-118125519129463
Pubmed

The SLC16 gene family-from monocarboxylate transporters (MCTs) to aromatic amino acid transporters and beyond.

SLC16A9 SLC16A5 SLC16A4 SLC16A7 SLC16A10

1.08e-0914125512739169
Pubmed

Localization of Xenobiotic Transporters Expressed at the Human Blood-Testis Barrier.

SLCO2B1 SLCO1B3 SLCO1B1 SLCO2A1 SLC22A4

2.34e-0916125535307651
Pubmed

Systematic protein-protein interaction mapping for clinically relevant human GPCRs.

ACTR10 ARL6IP5 SLCO4A1 SI TIMMDC1 SLC39A13 CCKBR TMEM33 OSTC TM9SF2 SLC41A3 SLC5A6 CD37 SLC37A4 MFSD10

3.45e-086971251528298427
Pubmed

SLCO1B1, SLCO2B1, and SLCO1B3 polymorphisms and susceptibility to bladder cancer risk.

SLCO2B1 SLCO1B3 SLCO1B1

4.53e-083125324762081
Pubmed

Impact of regulatory polymorphisms in organic anion transporter genes in the human liver.

SLCO2B1 SLCO1B3 SLCO1B1

4.53e-083125319620935
Pubmed

Comparison of genetic variations of the SLCO1B1, SLCO1B3, and SLCO2B1 genes among five ethnic groups.

SLCO2B1 SLCO1B3 SLCO1B1

4.53e-083125326409184
Pubmed

Organic Anion Transporting Polypeptides Contribute to the Disposition of Perfluoroalkyl Acids in Humans and Rats.

SLCO2B1 SLCO1B3 SLCO1B1

4.53e-083125328013215
Pubmed

Identification of novel cell-impermeant fluorescent substrates for testing the function and drug interaction of Organic Anion-Transporting Polypeptides, OATP1B1/1B3 and 2B1.

SLCO2B1 SLCO1B3 SLCO1B1

4.53e-083125329422623
Pubmed

Organic anion transporting polypeptide (OATP)-mediated transport of coproporphyrins I and III.

SLCO2B1 SLCO1B3 SLCO1B1

4.53e-083125326383540
Pubmed

Organic Anion Transporting Polypeptide-Mediated Hepatic Uptake of Glucuronide Metabolites of Androgens.

SLCO2B1 SLCO1B3 SLCO1B1

4.53e-083125332587096
Pubmed

The European renal genome project: an integrated approach towards understanding the genetics of kidney development and disease.

SLC6A19 SLCO1B3 SLCO1B1 SLC2A5 SLC41A2 SLCO4C1 SLC34A1 SLC18A1 SLC16A10

8.13e-08212125919521566
Pubmed

The human olfactory receptor gene family.

OR4N2 OR9G1 OR2T27 OR4N4 OR2T7 OR10Q1 OR2T1 OR11H6 OR3A2 OR6F1 OR52A5 OR7D2 OR2H2

8.48e-085411251314983052
Pubmed

Digoxin is not a substrate for organic anion-transporting polypeptide transporters OATP1A2, OATP1B1, OATP1B3, and OATP2B1 but is a substrate for a sodium-dependent transporter expressed in HEK293 cells.

SLCO2B1 SLCO1B3 SLCO1B1

1.81e-074125321849517
Pubmed

Influence of SLCO1B1, 1B3, 2B1 and ABCC2 genetic polymorphisms on mycophenolic acid pharmacokinetics in Japanese renal transplant recipients.

SLCO2B1 SLCO1B3 SLCO1B1

1.81e-074125317906856
Pubmed

Molecular identification and characterization of novel members of the human organic anion transporter (OATP) family.

SLCO2B1 SLCO4A1 SLCO1B1

4.51e-075125310873595
Pubmed

Polymorphisms of the nuclear receptor pregnane X receptor and organic anion transporter polypeptides 1A2, 1B1, 1B3, and 2B1 are not associated with breast cancer risk.

SLCO2B1 SLCO1B3 SLCO1B1

4.51e-075125320635135
Pubmed

Expert curation of the human and mouse olfactory receptor gene repertoires identifies conserved coding regions split across two exons.

OR2T27 OR2T7 OR14I1 OR7D2 OR4N4C

6.74e-0746125532126975
Pubmed

Human metabolic individuality in biomedical and pharmaceutical research.

SLC2A9 SLC16A9 SLCO1B1 SLC22A4 SLC16A10

1.99e-0657125521886157
Pubmed

Maternal bile acid transporter deficiency promotes neonatal demise.

SLCO2B1 SLCO4A1 PTGS2 SLC10A2 SLCO4C1

2.37e-0659125526416771
Pubmed

Developmental and cell type-specific expression of thyroid hormone transporters in the mouse brain and in primary brain cells.

SLCO4A1 SLCO4C1 SLC16A10

3.75e-069125321264952
Pubmed

An atlas of genetic influences on human blood metabolites.

SLC2A9 SLC16A9 SLCO1B1 RNF167 SLC5A6 SLC22A4 SLC16A10

6.02e-06190125724816252
Pubmed

ApoL1 renal risk variants induce aberrant THP-1 monocyte differentiation and increase eicosanoid production via enhanced expression of cyclooxygenase-2.

APOL1 PTGS2

1.28e-052125229357411
Pubmed

Phospholipase A2 and cyclooxygenase 2 genes influence the risk of interferon-alpha-induced depression by regulating polyunsaturated fatty acids levels.

PTGS2 PLA2G4A

1.28e-052125220034614
Pubmed

Spatial and temporal alterations of phospholipids determined by mass spectrometry during mouse embryo implantation.

PTGS2 PLA2G4A

1.28e-052125219429885
Pubmed

The impact of PLA2G4A and PTGS2 gene polymorphisms, and red blood cell PUFAs deficit on niacin skin flush response in schizophrenia patients.

PTGS2 PLA2G4A

1.28e-052125223219238
Pubmed

Modulation of transporter activity of OATP1B1 and OATP1B3 by the major active components of Radix Ophiopogonis.

SLCO1B3 SLCO1B1

1.28e-052125229944058
Pubmed

SLCO1B1 and SLCO1B3 genetic mutations in Taiwanese patients with Rotor syndrome.

SLCO1B3 SLCO1B1

1.28e-052125236964102
Pubmed

Genetic analysis of alpha-latrotoxin receptors reveals functional interdependence of CIRL/latrophilin 1 and neurexin 1 alpha.

ADGRL1 NRXN1

1.28e-052125211741895
Pubmed

SLCO1B3 and SLCO2B1 genotypes, androgen deprivation therapy, and prostate cancer outcomes: a prospective cohort study and meta-analysis.

SLCO2B1 SLCO1B3

1.28e-052125237856781
Pubmed

Risk of Developing Hepatocellular Carcinoma following Depressive Disorder Based on the Expression Level of Oatp2a1 and Oatp2b1.

SLCO2B1 SLCO2A1

1.28e-052125231467884
Pubmed

Contribution of OATP1B1 and OATP1B3 to the disposition of sorafenib and sorafenib-glucuronide.

SLCO1B3 SLCO1B1

1.28e-052125223340295
Pubmed

Further Studies to Support the Use of Coproporphyrin I and III as Novel Clinical Biomarkers for Evaluating the Potential for Organic Anion Transporting Polypeptide 1B1 and OATP1B3 Inhibition.

SLCO1B3 SLCO1B1

1.28e-052125229777022
Pubmed

Down-regulation of OATP1B proteins correlates with hyperbilirubinemia in advanced cholestasis.

SLCO1B3 SLCO1B1

1.28e-052125226191226
Pubmed

Targeting Deficiencies in the TLR5 Mediated Vaginal Response to Treat Female Recurrent Urinary Tract Infection.

DEFB4A TLR5

1.28e-052125228887442
Pubmed

Utility of Oatp1a/1b-knockout and OATP1B1/3-humanized mice in the study of OATP-mediated pharmacokinetics and tissue distribution: case studies with pravastatin, atorvastatin, simvastatin, and carboxydichlorofluorescein.

SLCO1B3 SLCO1B1

1.28e-052125224194513
Pubmed

Evaluation of organic anion transporting polypeptide 1B1 and 1B3 humanized mice as a translational model to study the pharmacokinetics of statins.

SLCO1B3 SLCO1B1

1.28e-052125224855184
Pubmed

Cytosolic phospholipase A2 alpha amplifies early cyclooxygenase-2 expression, oxidative stress and MAP kinase phosphorylation after cerebral ischemia in mice.

PTGS2 PLA2G4A

1.28e-052125220673332
Pubmed

Preclinical Mouse Models To Study Human OATP1B1- and OATP1B3-Mediated Drug-Drug Interactions in Vivo.

SLCO1B3 SLCO1B1

1.28e-052125226474710
Pubmed

Effects of anthocyans on the expression of organic anion transporting polypeptides (SLCOs/OATPs) in primary human hepatocytes.

SLCO1B3 SLCO1B1

1.28e-052125225578040
Pubmed

The CCK-2/gastrin splice variant receptor retaining intron 4 transactivates the COX-2 promoter in vitro.

PTGS2 CCKBR

1.28e-052125217936921
Pubmed

Prediction of organic anion-transporting polypeptide 1B1- and 1B3-mediated hepatic uptake of statins based on transporter protein expression and activity data.

SLCO1B3 SLCO1B1

1.28e-052125224989890
Pubmed

The expression of brain cyclooxygenase-2 is down-regulated in the cytosolic phospholipase A2 knockout mouse.

PTGS2 PLA2G4A

1.28e-052125214713302
Pubmed

Expression of organic anion-transporting polypeptides 1B1 and 1B3 in ovarian cancer cells: relevance for paclitaxel transport.

SLCO1B3 SLCO1B1

1.28e-052125221719246
Pubmed

Organic anion transporting polypeptide 1B1 (OATP1B1) and OATP1B3: genetic variability and haplotype analysis in white Canadians.

SLCO1B3 SLCO1B1

1.28e-052125220877131
Pubmed

Transport of fluorescent chenodeoxycholic acid via the human organic anion transporters OATP1B1 and OATP1B3.

SLCO1B3 SLCO1B1

1.28e-052125216534140
Pubmed

A study of a genetic association between the PTGS2/PLA2G4A locus and schizophrenia.

PTGS2 PLA2G4A

1.28e-052125215041036
Pubmed

Effect of pregnane X receptor ligands on transport mediated by human OATP1B1 and OATP1B3.

SLCO1B3 SLCO1B1

1.28e-052125218321482
Pubmed

Extra-hepatic metabolism of 7-ketocholesterol occurs by esterification to fatty acids via cPLA2α and SOAT1 followed by selective efflux to HDL.

PLA2G4A SOAT1

1.28e-052125225617738
Pubmed

Isolation and characterization of a digoxin transporter and its rat homologue expressed in the kidney.

SLCO1B3 SLCO4C1

1.28e-052125214993604
Pubmed

Interaction of oral antidiabetic drugs with hepatic uptake transporters: focus on organic anion transporting polypeptides and organic cation transporter 1.

SLCO1B3 SLCO1B1

1.28e-052125218314419
Pubmed

OATP 1B1/1B3 expression in hepatocellular carcinomas treated with orthotopic liver transplantation.

SLCO1B3 SLCO1B1

1.28e-052125221691816
Pubmed

Group IVA phospholipase Aâ‚‚ optimizes ovulation and fertilization in rodents through induction of and metabolic coupling with prostaglandin endoperoxide synthase 2.

PTGS2 PLA2G4A

1.28e-052125222673578
Pubmed

Cyclooxygenase-2 Mediated Oxidation of 2-Arachidonoyl-Lysophospholipids Identifies Unknown Lipid Signaling Pathways.

PTGS2 PLA2G4A

1.28e-052125227642067
Pubmed

Linking organic anion transporting polypeptide 1B1 and 1B3 (OATP1B1 and OATP1B3) interaction profiles to hepatotoxicity - The hyperbilirubinemia use case.

SLCO1B3 SLCO1B1

1.28e-052125228063966
Pubmed

Characterization of OATP1B3 and OATP2B1 transporter expression in the islet of the adult human pancreas.

SLCO2B1 SLCO1B3

1.28e-052125228493059
Pubmed

Long-lasting inhibitory effects of cyclosporin A, but not tacrolimus, on OATP1B1- and OATP1B3-mediated uptake.

SLCO1B3 SLCO1B1

1.28e-052125222240838
Pubmed

Human organic anion transporter 1B1 and 1B3 function as bidirectional carriers and do not mediate GSH-bile acid cotransport.

SLCO1B3 SLCO1B1

1.28e-052125217412826
Pubmed

Prostaglandin transporter (OATP2A1/SLCO2A1) contributes to local disposition of eicosapentaenoic acid-derived PGE3.

SLCO2B1 SLCO2A1

1.28e-052125226692285
Pubmed

Expression of SLCO transport genes in castration-resistant prostate cancer and impact of genetic variation in SLCO1B3 and SLCO2B1 on prostate cancer outcomes.

SLCO2B1 SLCO1B3

1.28e-052125221266523
Pubmed

Genetic polymorphisms of human organic anion transporters OATP-C (SLC21A6) and OATP-B (SLC21A9): allele frequencies in the Japanese population and functional analysis.

SLCO2B1 SLCO1B1

1.28e-052125212130747
Pubmed

BanI polymorphism of cytosolic phospholipase A2 gene and somatic symptoms in medication-free acute depressed patients.

PTGS2 PLA2G4A

1.28e-052125228108057
Pubmed

Visualization of hepatic uptake transporter function in healthy subjects by using gadoxetic acid-enhanced MR imaging.

SLCO1B3 SLCO1B1

1.28e-052125222771883
Pubmed

Establishment of a set of double transfectants coexpressing organic anion transporting polypeptide 1B3 and hepatic efflux transporters for the characterization of the hepatobiliary transport of telmisartan acylglucuronide.

SLCO1B3 SLCO1B1

1.28e-052125218180273
Pubmed

Structure of human drug transporters OATP1B1 and OATP1B3.

SLCO1B3 SLCO1B1

1.28e-052125237723174
Pubmed

Cytosolic phospholipase A2 is a key regulator of blood-brain barrier function in epilepsy.

PTGS2 PLA2G4A

1.28e-052125231661303
Pubmed

Arachidonic acid regulation of the cytosolic phospholipase A 2α/cyclooxygenase-2 pathway in mouse endometrial stromal cells.

PTGS2 PLA2G4A

1.28e-052125222369775
Pubmed

In focus in HCB.

SLCO2B1 SLCO1B3

1.28e-052125228815335
Pubmed

Effects of Rifampin, a potent inducer of drug-metabolizing enzymes and an inhibitor of OATP1B1/3 transport, on the single dose pharmacokinetics of anacetrapib.

SLCO1B3 SLCO1B1

1.28e-052125223670789
Pubmed

SLCO2B1 and SLCO1B3 may determine time to progression for patients receiving androgen deprivation therapy for prostate cancer.

SLCO2B1 SLCO1B3

1.28e-052125221606417
Pubmed

Bosentan is a substrate of human OATP1B1 and OATP1B3: inhibition of hepatic uptake as the common mechanism of its interactions with cyclosporin A, rifampicin, and sildenafil.

SLCO1B3 SLCO1B1

1.28e-052125217496208
Pubmed

Rotor Syndrome

SLCO1B3 SLCO1B1

1.28e-052125223236639
Pubmed

Expression Patterns of Organic Anion Transporting Polypeptides 1B1 and 1B3 Protein in Human Pediatric Liver.

SLCO1B3 SLCO1B1

1.28e-052125227098745
Pubmed

Introduction of aromatic ring-containing substituents in cyclic nucleotides is associated with inhibition of toxin uptake by the hepatocyte transporters OATP 1B1 and 1B3.

SLCO1B3 SLCO1B1

1.28e-052125224740327
Pubmed

UGT-dependent regioselective glucuronidation of ursodeoxycholic acid and obeticholic acid and selective transport of the consequent acyl glucuronides by OATP1B1 and 1B3.

SLCO1B3 SLCO1B1

1.28e-052125231299240
Pubmed

In vitro OATP1B1 and OATP1B3 inhibition is associated with observations of benign clinical unconjugated hyperbilirubinemia.

SLCO1B3 SLCO1B1

1.28e-052125223886114
Pubmed

OATP1B1/1B3 activity in plated primary human hepatocytes over time in culture.

SLCO1B3 SLCO1B1

1.28e-052125221787759
Pubmed

Tissue distribution, ontogeny, and hormonal regulation of xenobiotic transporters in mouse kidneys.

SLC10A2 SLCO4C1 SLC34A1

2.45e-0516125319679677
Pubmed

Neuronal 3',3,5-triiodothyronine (T3) uptake and behavioral phenotype of mice deficient in Mct8, the neuronal T3 transporter mutated in Allan-Herndon-Dudley syndrome.

SLCO4A1 SLCO4C1 SLC16A10

2.97e-0517125319641107
Pubmed

Different evolutionary processes shaped the mouse and human olfactory receptor gene families.

OR4N2 OR9G1 OR10Q1 OR2T1 OR11H6 OR6F1 OR52A5 OR2H2

3.35e-05340125811875048
Pubmed

The olfactory receptor gene superfamily of the mouse.

OR4N2 OR9G1 OR10Q1 OR2T1 OR11H6 OR6F1 OR52A5 OR2H2

3.35e-05340125811802173
Pubmed

Changes in thyroid status during perinatal development of MCT8-deficient male mice.

SLCO1B3 SLCO1B1 SLC16A10

3.56e-0518125323696569
Pubmed

A unified nomenclature for vertebrate olfactory receptors.

OR4N2 OR9G1 OR10Q1 OR2T1 OR11H6 OR6F1 OR52A5 OR2H2

3.57e-05343125832295537
Pubmed

Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels.

OR4N2 OR9G1 OR10Q1 OR2T1 OR11H6 OR6F1 OR52A5 OR2H2

3.79e-05346125814611657
Pubmed

Direct identification of the agonist binding site in the human brain cholecystokininB receptor.

SLCO1B3 CCKBR

3.84e-053125210320330
Pubmed

Preincubation With Everolimus and Sirolimus Reduces Organic Anion-Transporting Polypeptide (OATP)1B1- and 1B3-Mediated Transport Independently of mTOR Kinase Inhibition: Implication in Assessing OATP1B1- and OATP1B3-Mediated Drug-Drug Interactions.

SLCO1B3 SLCO1B1

3.84e-053125231047942
Pubmed

Multiple Genetic Modifiers of Bilirubin Metabolism Involvement in Significant Neonatal Hyperbilirubinemia in Patients of Chinese Descent.

SLCO1B3 SLCO1B1

3.84e-053125226146841
Pubmed

MICA-A5.1 allele is associated with atypical forms of celiac disease in HLA-DQ2-negative patients.

HLA-DQB1 MICA

3.84e-053125211862400
Pubmed

Progression of liver oncogenesis in the double transgenic mice c-myc/TGF α is not enhanced by cyclooxygenase-2 expression.

PTGS2 TGFA

3.84e-053125223579063
Pubmed

No association between the PPARG gene and schizophrenia in a British population.

PTGS2 PLA2G4A

3.84e-053125219560328
Pubmed

MICA is associated with type 1 diabetes in the Belgian population, independent of HLA-DQ.

HLA-DQB1 MICA

3.84e-053125216698430
Pubmed

Genetic variants of PTGS2, TXA2R and TXAS1 are associated with carotid plaque vulnerability, platelet activation and TXA2 levels in ischemic stroke patients.

TBXA2R PTGS2

3.84e-053125228704403
Pubmed

Characterization of organic anion transporting polypeptide 1b2-null mice: essential role in hepatic uptake/toxicity of phalloidin and microcystin-LR.

SLCO1B3 SLCO1B1

3.84e-053125218296417
Pubmed

Increased expression of monocarboxylate transporters 1, 2, and 4 in colorectal carcinomas.

SLC16A4 SLC16A7

3.84e-053125218188595
Pubmed

Effects of tuberculosis, race, and human gene SLCO1B1 polymorphisms on rifampin concentrations.

SLCO1B3 SLCO1B1

3.84e-053125220660695
Pubmed

Influence of genomic ancestry on the distribution of SLCO1B1, SLCO1B3 and ABCB1 gene polymorphisms among Brazilians.

SLCO1B3 SLCO1B1

3.84e-053125222136368
Pubmed

Genetic variations in monocarboxylate transporter genes as predictors of clinical outcomes in non-small cell lung cancer.

SLC16A4 SLC16A7

3.84e-053125225578492
Pubmed

Cross-talk between peroxisome proliferator-activated receptor delta and cytosolic phospholipase A(2)alpha/cyclooxygenase-2/prostaglandin E(2) signaling pathways in human hepatocellular carcinoma cells.

PTGS2 PLA2G4A

3.84e-053125217178883
Pubmed

Exposure to growth hormone is associated with hepatic up-regulation of cPLA2α and COX.

PTGS2 PLA2G4A

3.84e-053125232259636
InteractionMTX3 interactions

SLC2A9 SLC37A3 SLC24A3 SLC18A1 SLC5A6 SLC22A4

4.55e-06761146int:MTX3
InteractionORMDL2 interactions

TIMMDC1 SLCO1B1 SLC5A5 SLC5A6 SLC22A4

1.61e-05561145int:ORMDL2
InteractionSLCO1B3 interactions

SLCO1B3 SLCO1B1 CCKBR

2.06e-05101143int:SLCO1B3
InteractionORMDL1 interactions

SLC2A9 TIMMDC1 SLC18A1 SLC5A6 SLC22A4

3.87e-05671145int:ORMDL1
Cytoband1q44

OR2T27 OR2T7 OR2T1 OR14I1 OR6F1

1.34e-0511012551q44
CytobandEnsembl 112 genes in cytogenetic band chr1q44

OR2T27 OR2T7 OR2T1 OR14I1 OR6F1

2.79e-051281255chr1q44
Cytoband1q25

TPR PLA2G4A SOAT1

4.89e-052612531q25
GeneFamilySolute carriers

SLC2A9 SLC37A3 SLC16A9 SLCO2B1 SLC6A19 SLCO4A1 SLC26A9 SLCO1B3 SLC24A3 SLCO1B1 SLC39A13 SLC2A5 SLC5A5 SLC41A2 SLC17A5 SLC10A2 SLCO4C1 SLC16A5 SLC16A4 SLC41A3 SLC34A1 SLC18A1 SLCO2A1 SLC5A6 SLC22A4 SLC4A10 SLC49A3 SLC25A29 SLC16A7 SLC37A4 SLC16A10

1.34e-283959331752
GeneFamilyGuanylate cyclase receptors

NPR2 GUCY2D

5.41e-047932343
CoexpressionSERVITJA_LIVER_HNF1A_TARGETS_DN

SLCO1B3 SLCO1B1 SLC41A2 SLCO2A1 PKHD1 PLA2G4A SLC37A4 SLC16A10

3.13e-061901228MM1311
CoexpressionSERVITJA_LIVER_HNF1A_TARGETS_DN

SLCO1B3 SLC41A2 SLCO2A1 PKHD1 PLA2G4A SLC37A4 SLC16A10

1.31e-051661227M2398
CoexpressionGSE40685_NAIVE_CD4_TCELL_VS_FOXP3_KO_TREG_PRECURSOR_DN

DOCK3 HYAL1 ADGRL1 SLC2A5 SLC25A29 OR2H2 SLC16A10

3.69e-051951227M9309
CoexpressionGSE30971_WBP7_HET_VS_KO_MACROPHAGE_2H_LPS_STIM_DN

SLC37A3 SLCO4A1 PTGS2 TGFA PLA2G4A TM4SF1 SLC16A10

4.06e-051981227M8723
CoexpressionGSE23695_CD57_POS_VS_NEG_NK_CELL_DN

ATP6V1A MFSD11 PTGS2 RNF167 SLC5A6 SDHC SLC16A10

4.33e-052001227M7786
CoexpressionAtlaskidney_adult_RenalCortexMixed_Std_top-relative-expression-ranked_1000

ATP6V1A SLC16A9 HLA-DQB1 SLC6A19 PTGR2 SLC2A5 ADK SLC17A5 SLC10A2 SLCO4C1 SLC16A4 SLC34A1 SLC18A1 SLC22A4 PKHD1 SLC16A7 SLC37A4

3.03e-0686111317gudmap_kidney_adult_RenalCortexMixed_Std_1000
CoexpressionAtlaskidney single cell_adult_RenalCortexMixed_StemCellamp_k-means-cluster#1_top-relative-expression-ranked_1000

ATP6V1A HLA-DQB1 MFSD11 SLC6A19 PTGR2 SLC2A5 ADK RNF167 SLC10A2 TM9SF2 SLC16A4 SLC34A1 SLC18A1 SLC22A4 SLC37A4

3.47e-0583111315gudmap_kidney single cell_adult_RenalCortexMixed_Scamp_k1_1000
CoexpressionAtlaskidney

SLC2A9 SLC16A9 SLC6A19 SLC10A2 SLCO4C1 SLC16A4 SLC34A1 PKHD1 SLC37A4

5.82e-053231139kidney
CoexpressionAtlaskidney single cell_adult_RenalCortexMixed_StemCellamp_top-relative-expression-ranked_1000

ATP6V1A HLA-DQB1 MFSD11 SLC6A19 PTGR2 SLC2A5 ADK RNF167 SLC10A2 TM9SF2 SLC16A4 SLC34A1 SLC18A1 SLC22A4 SLC37A4

7.26e-0588711315gudmap_kidney single cell_adult_RenalCortexMixed_Scamp_1000
CoexpressionAtlaskidney_adult_JuxtaGlom_Ren1_top-relative-expression-ranked_1000

ATP6V1A HLA-DQB1 SLC6A19 PTGR2 SLC2A5 SLC16A4 SLC34A1 SLC18A1 SLCO2A1 PKHD1 TM4SF1 SLC16A7 SLC37A4 SLC16A10

8.86e-0579911314gudmap_kidney_adult_JuxtaGlom_Ren1_1000
CoexpressionAtlasMyeloid Cells, MF.Thio5.II+480int.PC, CD115+ MHC II+ F480lo SiglecF- CD11c+, Peritoneal Cavity, avg-3

ATP6V1A SLCO2B1 HLA-DQB1 MFSD11 ABCA9 SLC41A2 SLC17A5 SLC16A7 SOAT1 SLC16A10

1.07e-0443311310GSM605856_500
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SLC26A9 SLC24A3 ADK HHIP SLC16A5 TM4SF1 MVP

8.27e-071861227acfa68a2afb7d2b51c9b469a1965fe5cc5d5e64e
ToppCell3'-Adult-SmallIntestine|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HLA-DQB1 SLC6A19 SI SLC10A2 PTGR1 CD37 TM4SF1

1.21e-0619712271614bc5f41fd2c8385e58ed6b87ef1536421f29a
ToppCellkidney_cells-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ATP6V1A ANK2 SLC16A9 SLC6A19 SLC2A5 SLC34A1

3.00e-06145122647a3bb973a508d3097213a2d86ad1ce697af9bae
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-Epcam____brush_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC16A9 SLC2A5 SLCO4C1 SLC16A4 SLC18A1 SLC5A6

7.00e-06168122635ce3b2b9c9997d4c101da5949c7271d6a6b8f12
ToppCellCOVID-19-kidney-Stressed_PCT|COVID-19 / Disease (COVID-19 only), tissue and cell type

SLC2A9 SLC16A9 SLC6A19 SLCO4C1 SLC34A1 PKHD1

1.07e-0518112266980ea624151da32b7f537f263e40fcb87a02e81
ToppCelldroplet-Kidney-nan-3m-Epithelial-Epcam____kidney_proximal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC16A9 SLC6A19 SLC16A4 SLC34A1 SLC18A1 SLC37A4

1.21e-0518512263e3217c99719fd1d2fa94e16be7712a7e5077152
ToppCelldroplet-Kidney-nan-3m-Epithelial-kidney_proximal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC16A9 SLC6A19 SLC16A4 SLC34A1 SLC18A1 SLC37A4

1.21e-0518512260ff4148b4701003d9d594e0da8261176fb13aa59
ToppCellPBMC-Severe-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-10|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ANK2 HLA-DQB1 CXXC5 DUSP15 ADK SLC25A29

1.25e-051861226d7d884ff4184636081c350d29f797bd923c6a3b4
ToppCellkidney_cells-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TMEM88 HLA-DQB1 APOL1 SLCO2A1 FLRT2 TM4SF1

1.54e-051931226daefbfd3a3dd1351fbe94b9abfd807db44d56c24
ToppCellfacs-Brain_Myeloid-Cortex_-18m-Myeloid-microglial_cell|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLCO2B1 GAL3ST4 SIPA1 SLC2A5 ADIPOR1 TM9SF2

1.73e-051971226173c0c8de4e69882a9f91189deeb4a651fefe551
ToppCellEpithelial_cells-Epithelial_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

ANK2 SLC16A9 SLC6A19 SLC16A4 PTGR1 SLC34A1

1.78e-05198122652e9d41a1726bc1140df6baec9f17a534448ac8b
ToppCell5'-Adult-SmallIntestine-Epithelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC6A19 SI SLC2A5 SLC10A2 PTGR1 SLC37A4

1.78e-0519812268d629492d2199de8e036c19e9dacceb9c9e721a0
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ANK2 SLC16A9 SLC6A19 SLC16A4 SLC34A1 SLC37A4

1.78e-051981226a9d72b17adfddb6ac1857c5f094280e86582693b
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ANK2 SLC16A9 SLC6A19 SLC16A4 SLC34A1 SLC37A4

1.78e-051981226b933bd66f544822fcf1f2aa2d928c31500e2b3f4
ToppCell5'-Adult-SmallIntestine-Epithelial-mature_enterocytic-Enterocyte|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC6A19 SI SLC2A5 SLC10A2 PTGR1 SLC37A4

1.78e-0519812266e6af8fad09f8e48b3f2ce463d5773b6a69864d1
ToppCellEpithelial_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

ANK2 SLC16A9 SLC6A19 SLC16A4 PTGR1 SLC34A1

1.78e-051981226eeec789d226171f30799577cc37c07bdced2e3cb
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ANK2 SLC16A9 SLC6A19 SLC16A4 SLC34A1 SLC37A4

1.83e-0519912264bde35e5df019189433d65d415e29a0c1145ac66
ToppCell5'-Adult-SmallIntestine|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC6A19 SI SLC2A5 SLC10A2 PTGR1 SLC37A4

1.83e-051991226a5fffe381be1ba7d192b68d1d3937ce47663658e
ToppCell5'-Adult-SmallIntestine-Epithelial-mature_enterocytic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC6A19 SI SLC2A5 SLC10A2 PTGR1 SLC37A4

1.83e-05199122601c2721bc82cd672e9477029b4a7ecc77e2f1b00
ToppCellSevere-Myeloid-Macrophages-FCN1-SPP1+|Severe / Condition, Lineage, Cell class and cell subclass

ATP6V1A SLCO2B1 HLA-DQB1 HSD3B7 SOAT1 SLC16A10

1.89e-052001226b8cd209b810312793465b28bb2a6cbe5d94da91f
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Myeloid-Granulocytic-Neutrophil-Neu_c2-CXCR4(low)|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SLC24A3 SLC5A5 HHIP SLC10A2 SLC22A4

4.81e-0514412253d880c140db4a0e7602bfddcb73a42a68c2848d5
ToppCellfacs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK3 CCKBR PKHD1 MYO15A HYDIN

4.97e-05145122596712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCellBronchial_Biopsy-Epithelial-Goblet_1|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X

SLC16A9 SLCO4A1 SLCO1B3 SLC5A5 TM4SF1

4.97e-051451225e932361734839c14ffa0c1e028dcef9c833f884f
ToppCell10x5'-GI_small-bowel-Lymphocytic_Invariant-Inducer-like-MAIT|GI_small-bowel / Manually curated celltypes from each tissue

SLCO1B1 TMEM200B SLC10A2 SLCO4C1 SLC4A10

5.13e-0514612251cb2e157222631e8915d89b255a843d16d7d99cc
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Epithelial-neuronal_stem_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC26A9 SLC24A3 PTGS2 TLR5 SLC16A10

5.84e-05150122547ea08d7609e1d2382bf56ef9e5c767e3597cf93
ToppCell390C-Myeloid-Macrophage-SPP1+_Macrophage_2|390C / Donor, Lineage, Cell class and subclass (all cells)

SLC2A9 SLCO2B1 NRG2 GAL3ST4 SLC16A10

6.82e-05155122515bacd06cc2b02b13c85bb71c5b758e5ff613e80
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-high_Fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SLC24A3 ABCA9 PLA2G4A FLRT2 OR2H2

7.69e-051591225e812cbde59188924c6277c3feadf1a9592fa62a4
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-high_Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SLC24A3 ABCA9 PLA2G4A FLRT2 OR2H2

7.69e-0515912252607b562903228274fbd96168ba826782fab0b53
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-brush_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC16A9 SLC2A5 SLC16A4 SLC18A1 SLC5A6

8.40e-0516212256972d45f4bd4b6522bf93295f7e9dca7c6cba1f3
ToppCellsaliva-Severe-critical_progression_d28-40-Myeloid-Dendritic-conventional_dendritic_cell-DC_c1-CLEC9A|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SLCO2B1 HLA-DQB1 ADGRL1 SLC41A2 GUCY2D

9.16e-05165122560b500eb2c10cccf309b8fb28a9119da22d6889c
ToppCellfacs-Marrow-B-cells-24m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLCO4A1 SLC24A3 GAL3ST4 ST3GAL3 SLC41A3

9.42e-05166122513027ae342994db4540e64eb910df1f42b160931
ToppCellfacs-Marrow-B-cells-24m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLCO4A1 SLC24A3 GAL3ST4 ST3GAL3 SLC41A3

9.42e-051661225b21e45bd43f26149b9cd6e45c19241c82d54fb2f
ToppCelldroplet-Kidney-nan-3m-Epithelial-Epcam____brush_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NPR2 SLC24A3 SLC2A5 SLC10A2 SLC16A4

9.69e-05167122540d102e01ccbc7262d00fafd59ca5234909009cb
ToppCell5'-Adult-SmallIntestine-Epithelial-Tuft-related-Tuft|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NRG2 SLC18A1 PLA2G4A CHD6 MGAM2

9.96e-0516812258072d0496b7b730c4601009eaa69ec5366d26d73
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic_B-B_atypical|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

HLA-DQB1 VASN CXXC5 DUSP15 ADK

1.14e-041731225f135cc9dcf34f33ced3210171ab40ae6d77cfae0
ToppCell390C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-2|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

HLA-DQB1 ST3GAL3 DDIAS HSD3B7 PTGR1

1.14e-041731225b9dee61973559e8c2fef3f2dafd43475b386befb
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic_B-B_atypical-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

HLA-DQB1 VASN CXXC5 DUSP15 ADK

1.14e-04173122523248019c819f6e38337dcc4edb763ef1992e89e
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC24A3 ABCA9 HHIP NRXN1 FLRT2

1.17e-0417412259c916af5eebd932f67dc9117e1d26ff194a2ff2c
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC24A3 ABCA9 HHIP NRXN1 FLRT2

1.17e-041741225bc71521f44a5fe013af42b06b5d1bd2446ecf3b5
ToppCell390C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

HLA-DQB1 ST3GAL3 DDIAS HSD3B7 PTGR1

1.24e-041761225437cfc5e06416bb0fc76d1f9dc106f74e279e880
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Myeloid-microglial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GAL3ST4 ABCA9 SLC2A5 CD37 TLR5

1.27e-041771225201b0a8e6402a18aff0bb7c14f2bdd34fdf0db32
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Myeloid-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GAL3ST4 ABCA9 SLC2A5 CD37 TLR5

1.27e-0417712252a63288d09efd217b277aeecf957811a095f56e7
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Myeloid|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GAL3ST4 ABCA9 SLC2A5 CD37 TLR5

1.27e-04177122556fe389ffab73e3bc64f837b152d5907e3517a91
ToppCell3'-GW_trimst-2-LargeIntestine-Endothelial-lymphatic_endothelial-LEC2_(MADCAM1+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CMKLR2 HYAL1 SLC26A9 TGFA HSD3B7

1.27e-041771225d6596a0b6fd146fefc27717c1a7dbaa3774cc644
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.6.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SLCO2B1 HLA-DQB1 CD37 SLC49A3 SOAT1

1.27e-041771225929cd8f530ce001623735da53b7278d02522e2b5
ToppCell367C-Endothelial_cells-Endothelial-B_(Artery)|367C / Donor, Lineage, Cell class and subclass (all cells)

TMEM88 HYAL1 SLCO4A1 SLCO2A1 TM4SF1

1.31e-041781225e1e96a0e3ff718ebf676a982bc63e8ced6984059
ToppCellCOVID-19-kidney-PCT-S1/S2|COVID-19 / Disease (COVID-19 only), tissue and cell type

SLC2A9 SLC16A9 SLC6A19 SLC34A1 PKHD1

1.31e-04178122523a12d3d971b857d5be8e907334d1f6b49eeeb32
ToppCelldroplet-Fat-BAT+GAT+MAT-30m-Epithelial|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC26A9 TMEM132B SLC2A5 MYO15A HYDIN

1.31e-04178122558857bb8c13e0e1c6d9f5c1258f00fff62063d68
ToppCell367C-Endothelial_cells-Endothelial-B_(Artery)-|367C / Donor, Lineage, Cell class and subclass (all cells)

TMEM88 HYAL1 SLCO4A1 SLCO2A1 TM4SF1

1.31e-041781225363e8b23b3834692a8a79e5fdc7b43bd3a4dab5e
ToppCelldroplet-Fat-BAT+GAT+MAT-30m-Epithelial-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC26A9 TMEM132B SLC2A5 MYO15A HYDIN

1.31e-0417812258b7df6ab8709d9ab9dff97677cc4561aec2745bc
ToppCelldroplet-Fat-BAT+GAT+MAT-30m-Epithelial-epithelial_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC26A9 TMEM132B SLC2A5 MYO15A HYDIN

1.31e-041781225b0baf5667e3301898b3e45e974b8a8530af6a338
ToppCell5'-GW_trimst-1.5-SmallIntestine-Endothelial-lymphatic_endothelial-LEC2_(MADCAM1+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CMKLR2 SLC26A9 TGFA HSD3B7 FLRT2

1.34e-041791225dfd5b25f2a6a5a8bf4714f1516cb0997de72b06f
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_I-A|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TMEM88 SLCO2B1 HLA-DQB1 SLC2A5 CD37

1.34e-0417912253d3716078afdb9a89ddfadb3197cd1b52fa770be
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC2A9 ANK2 SLC16A9 SLC6A19 SLC34A1

1.38e-041801225f8bdfd7bf7b3d52c659a29d8f5f80858e79da83e
ToppCellFetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DOCK3 SLC16A9 HHIP FLRT2 TMEM200C

1.41e-04181122525915e2500430a902db37d79a749ce2990b69810
ToppCellsevere_influenza-B_intermediate|World / disease group, cell group and cell class (v2)

ANK2 HLA-DQB1 CXXC5 DUSP15 ADK

1.45e-041821225e633a908a2fb30ed362cf22fbb8d6839f31f1751
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC2A9 ANK2 SLC16A9 SLC6A19 SLC34A1

1.49e-041831225facd6dbe0851b537d70a899ac7485714ab27d071
ToppCellCOVID-19-kidney-PCT-S1|COVID-19 / Disease (COVID-19 only), tissue and cell type

SLC2A9 SLC16A9 SLCO4C1 PKHD1 HYDIN

1.49e-0418312256878d14026c3df6aa12e45dfad94b32fa9d9b0b7
ToppCellfacs-Brain_Non-Myeloid-Striatum_|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GAL3ST4 ABCA9 SLC2A5 CD37 TLR5

1.49e-041831225824ecda1219fb596a01bf5cfeee29a6daa462098
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GAL3ST4 ABCA9 SLC2A5 CD37 TLR5

1.49e-04183122582b84ee065fb573688d59da97a327152a1ba294c
ToppCellCOVID-19-kidney-PCT-S1|kidney / Disease (COVID-19 only), tissue and cell type

SLC2A9 SLC16A9 SLCO4C1 PKHD1 HYDIN

1.53e-04184122551ed1ebfdef45149541917c66cbacad87072e51f
ToppCell3'-Adult-SmallIntestine-Epithelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC6A19 SI SLC10A2 PTGR1 MGAM2

1.53e-041841225ed7a8e79e5723a5f5a03f542203d9e50bdef5f50
ToppCellfacs-Marrow-Granulocytes-3m-Myeloid-granulocyte_monocyte_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NRG2 SLCO4A1 SLCO4C1 PTGR1 SLC22A4

1.56e-04185122553854a9ec87c24c360541c83d86d8fafb303ad58
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLCO4A1 DUSP15 SLC16A5 SLC22A4 SLC16A7

1.56e-041851225af86e75096c1812ae27a78405355957ee8043d84
ToppCellfacs-Marrow-Granulocytes-3m-Myeloid-granulocyte_monocyte_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NRG2 SLCO4A1 SLCO4C1 PTGR1 SLC22A4

1.56e-041851225a61fc7a3700a1efcf640bef7680c0443ee148a46
ToppCellfacs-Thymus-Flowthrough-3m-Lymphocytic-DN_to_DP_transition_(most_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBXA2R SLC6A19 LBR SLC16A5 SOAT1

1.56e-041851225dc59b8dc459a3c444c9634a0d438cbef54c40036
ToppCellsystemic_lupus_erythematosus-managed-Lymphocytic_B-B_atypical-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

HLA-DQB1 VASN SLCO4A1 DUSP15 CD37

1.56e-04185122553960307c6710401c3d52a766c3f4704ace9637f
ToppCell3'-Adult-SmallIntestine-Epithelial-mature_enterocytic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC6A19 SI SLC10A2 PTGR1 MGAM2

1.60e-041861225bdd9d3a432aab46e733469b362f0064d35c1ac49
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_INF|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SLCO2B1 HLA-DQB1 GAL3ST4 SLC2A5 CD37

1.60e-041861225e4de270d38bbed022f545bd0bbaa9599e707ec87
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SLC2A9 SLC16A9 SLC6A19 SLC34A1 PKHD1

1.60e-0418612255784d255e9ca449d375d81938d0fbbd8a7eb44f6
ToppCell3'-Adult-SmallIntestine-Epithelial-mature_enterocytic-Enterocyte|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC6A19 SI SLC10A2 PTGR1 MGAM2

1.64e-0418712259042bd0f57213a51503d9df2e4dce3209b7772d3
ToppCelldroplet-Thymus-nan-18m-Myeloid-nan|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HYAL1 VASN SLC22A4 TM4SF1 HYDIN

1.64e-041871225ed69e7cbd6fb59363b0e26f24887fc49405397ce
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SLC2A9 SLC16A9 SLC16A4 SLC34A1 PKHD1

1.64e-0418712253ae3b8de1a195d4d5057cf3c64fcdb5f48681ce5
ToppCellCOVID-19-kidney-Fibroblast-1|COVID-19 / Disease (COVID-19 only), tissue and cell type

SLC24A3 ABCA9 PTGS2 PLA2G4A FLRT2

1.64e-04187122576bfe8c42430a230a8bdf299575c444fb7780f24
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_B-B_atypical-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

HLA-DQB1 VASN CXXC5 DUSP15 ADK

1.69e-041881225ef05d2fb17fd427d46d454e67073e0e1b45bb24c
ToppCellnormal-na-Lymphocytic_B-B_atypical-female|normal / PBMC cell types (v2) per disease, treatment status, and sex

ANK2 HLA-DQB1 DUSP15 ADK CD37

1.69e-041881225e5ab89030783461e9367ab87c353fb5c31911020
ToppCellnormal-na-Lymphocytic_B-B_atypical|normal / PBMC cell types (v2) per disease, treatment status, and sex

ANK2 HLA-DQB1 DUSP15 ADK CD37

1.69e-04188122513653481d64c7a1ad833d738a3ee0bb9def7cec7
ToppCellfacs-Thymus-Flowthrough-3m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBXA2R SLC6A19 LBR SLC16A5 SOAT1

1.69e-04188122559b71462338a7efbacf46577cb07e9db3363afee
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_B-B_atypical|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

HLA-DQB1 VASN CXXC5 DUSP15 ADK

1.73e-041891225ebaf722738c71d5f33f72341f801c6880f4aee14
ToppCellfacs-Pancreas-Endocrine-24m|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANK2 ADGRL1 SLC2A5 NRXN1 CD37

1.73e-041891225010fdd70e9d0e21b856306a29ff877776a480319
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell-B_c04-SOX5-TNFRSF1B|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

HLA-DQB1 CXXC5 ADK SLC5A6 SLC25A29

1.77e-041901225ed100e271aac82806f59e0c613ccda63f59100c1
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_anti-infl-A|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SLCO2B1 SLC17A5 TLR5 SLC49A3 HERC4

1.77e-04190122563018acb7ad80415e861643162abdc2e55968ee4
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_aging_sig-B|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SLC2A9 SLCO2B1 SLC2A5 OR3A2 CD37

1.81e-041911225a4200717672e2358eb649eae2553f293b4fd8f7e
ToppCellfacs-Brain_Myeloid|facs / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLCO2B1 GAL3ST4 ABCA9 SLC2A5 CD37

1.81e-041911225bf1135b382a3bf8cddc19538bc38361ef1fc2de1
ToppCellCOVID-19_Severe-B_intermediate|World / disease group, cell group and cell class

ANK2 HLA-DQB1 CXXC5 DUSP15 CD37

1.81e-041911225f226fd69a26124ba98e4544f550b89a08e6a3708
ToppCellIPF-Epithelial-Club|Epithelial / Disease state, Lineage and Cell class

SLC24A3 SLC5A5 DEFB4A TM4SF1 SLC16A7

1.86e-041921225356e7a820b744a0ac87352a8d0e6e8d9fa9ed7d2
ToppCellsystemic_lupus_erythematosus-managed-Lymphocytic_B-B_atypical|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

HLA-DQB1 VASN DUSP15 ADK CD37

1.86e-04192122524797e80b1f5b3ea5a0410caaf57ccf2ae9d716e
ToppCellControl-B_intermediate-10|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)

ANK2 VASN DUSP15 SLCO4C1 SLC25A29

1.86e-041921225224bd958369ba8fa0d7be2126f7dc61c9f6ac19d
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_aging_sig-C|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SLC2A9 SLCO2B1 HLA-DQB1 SLC2A5 CD37

1.86e-0419212254037b4c4fbb40541b8c424c36d3871a57891b8dd
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SLC26A9 ADK HHIP SLCO4C1 PKHD1

1.86e-041921225fb2f0e897228f808d9ff734ad05e9b49dc38fa50
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SLC16A9 SLC6A19 SLC26A9 SLC2A5 SLC16A4

1.86e-0419212253e1a4cb0d83efd502c8613d41a1692bdda5860ed
ToppCellfacs-Marrow-KLS-18m-Myeloid-granulocyte_monocyte_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NRG2 MRPS2 SLC22A4 SLC37A4 SLC16A10

1.90e-041931225f92bbe70e6c725bfb8c08bfc2a94e375528151a3
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_I-Z|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SLCO2B1 HLA-DQB1 GAL3ST4 SLC2A5 CD37

1.90e-041931225fc2eb6a7b4f1e687bf37e59e3cd52b14f99ffea4
ToppCell5'-Adult-Appendix-Endothelial-blood_vessel_EC-Mature_venous_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TMEM88 SLCO1B3 PTGS2 SLCO2A1 TM4SF1

1.90e-041931225c0973a2c97deb7176c2f617c8760a55f7edc9839
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-Mono-Mono_anti-infl-C|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SLC2A9 SLCO2B1 HLA-DQB1 GAL3ST4 CD37

1.90e-04193122579a95ac4f46abee00e03700c10cdb00c4507ea76
ToppCellfacs-Marrow-KLS-18m-Myeloid-granulocyte_monocyte_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NRG2 MRPS2 SLC22A4 SLC37A4 SLC16A10

1.90e-04193122544ba79db566d0fa3bbcfe3adf9164bf8c3cb0bc3
ToppCellMacrophages-SSc-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

SLCO2B1 HSD3B7 SLC18A1 CD37 SLC16A10

1.90e-041931225642f8f20e5a35a4b5d1fc8d3f1e3b9b83a37a654
ToppCellileum-Absorptive_Enterocytes|ileum / shred on tissue and cell subclass

SI SLC10A2 PTGR1

1.92e-04411223650cec538c6acd92f45d804b3c94248c6231aa21
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TMEM88 HLA-DQB1 SLCO2A1 FLRT2 TM4SF1

1.95e-041941225cf9cf115dbbb9997f7c303ae07f42f3d80ff9a21
ToppCellsystemic_lupus_erythematosus-managed-Lymphocytic_B-B_atypical-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

HLA-DQB1 VASN DUSP15 ADK CD37

1.95e-041941225b8f05efb16fbed7317019efc3da7f97f81e90972
ComputationalGenes in the cancer module 162.

SLC5A5 SLC10A2 SLC16A4 SLC34A1 SLC16A7

1.56e-0719755MODULE_162
ComputationalGenes in the cancer module 218.

SLC10A2 SLC16A4 SLC34A1 SLC16A7

9.73e-0620754MODULE_218
ComputationalGenes in the cancer module 71.

SLC10A2 SLC16A5 SLC16A4 SLC22A4

1.45e-0522754MODULE_71
ComputationalPeptide and AA transporters.

SLC10A2 SLC16A4 SLC34A1

2.47e-0418753MODULE_368
Drugsulfinpyrazone

SLC16A9 SLCO2B1 SLCO4A1 SLCO1B3 SLCO1B1 PTGS2 SLC2A5 SLC17A5 SLC10A2 SLCO4C1 SLCO2A1 SLC16A7

3.69e-148712112CID000005342
Drugcimetidine

SLC16A9 SLCO2B1 SLCO4A1 SLCO1B3 SLCO1B1 PTGS2 CCKBR SLC17A5 SLC10A2 SLCO4C1 SLCO2A1 SLC22A4 SLC16A7

1.33e-1117912113CID000002756
Drugprobenecid

SLC16A9 SLCO2B1 SLCO4A1 SLCO1B3 SLCO1B1 SLC17A5 SLC10A2 SLCO4C1 SLC16A5 SLCO2A1 SLC16A7

5.62e-1112312111CID000004911
DrugDigocin

DSG1 SLCO2B1 SLCO1B3 SLCO1B1 ABCA9 SLCO4C1 NRXN1 SLCO2A1

3.61e-09701218CID000003062
Drug17beta-estradiol glucuronide

SLCO2B1 SLCO4A1 SLCO1B3 SLCO1B1 SLC10A2 SLCO2A1

1.61e-08321216CID000066424
DrugNSC 117356

SLC16A9 SLCO2B1 SLCO4A1 SLCO1B3 LBR SLCO1B1 SLC17A5 SLC10A2 SLCO4C1 SLCO2A1 SLC16A7

8.41e-0824612111CID000004112
Drugsodium cholate

SLCO2B1 SLCO4A1 SLCO1B3 APOL1 SLCO1B1 PTGS2 CCKBR TGFA HSD3B7 SLC10A2 SLC34A1 SLC22A4 SOAT1

2.77e-0740812113CID000000303
Drugsodium

ATP6V1A SLC2A9 ANK2 SLCO2B1 ARL6IP5 SLCO4A1 OR2T1 SLC26A9 SLCO1B3 SLC24A3 SLCO1B1 SLC2A5 SLC5A5 SLC10A2 SLC34A1 SLC18A1 SLC5A6 SLC22A4 SLC16A10

5.77e-0794412119CID000000923
DrugDihydromicrocystin Lr

SLCO2B1 SLCO1B3 SLCO1B1

5.83e-0741213CID006441227
Drug15-ketoprostaglandin E2

PTGR2 PTGS2 PTGR1 SLCO2A1

9.90e-07151214CID000001441
Drug2,2',4,4',5,6'-hexabromodiphenyl ether

SLCO2B1 SLCO1B3 SLCO1B1

1.45e-0651213ctd:C555859
DrugOxycodone

SLCO1B3 SLC41A2 SLC17A5 SLC10A2 PLA2G4A SLC25A29 SLC37A4 SLC16A10

1.64e-061531218ctd:D010098
Drugprednisolone phosphate

SLCO2B1 SLCO1B3 SLCO1B1

2.89e-0661213CID000004896
DrugBQ 123

TBXA2R SLCO2B1 SLCO1B3 SLCO1B1 PTGS2

4.49e-06461215CID000123632
Druglumiracoxib

HLA-DQB1 PTGS2 SLCO2A1

5.05e-0671213ctd:C473384
Drugnateglinide

SLCO2B1 SLCO1B3 SLCO1B1

5.05e-0671213ctd:C060142
DrugAC1L1KSK

TBXA2R SLCO2B1 SLCO4A1 SLCO2A1

6.22e-06231214CID000005636
DrugNSC263652

SLCO2B1 SLCO1B3 SLCO1B1

8.04e-0681213CID000429721
Drug5-(N-(4-((4-ethylbenzyl)thio)phenyl)sulfamoyl)-2-methylbenzoic acid

SLCO2B1 SLCO1B3 SLCO1B1

1.20e-0591213ctd:C000588958
Drugtariquidar

SLCO1B3 LBR SLCO1B1 ADK

1.21e-05271214CID000148201
Drugsulfobromophthalein

SLCO2B1 SLCO4A1 SLCO1B3 SLCO1B1 SLC10A2 SLC37A4

1.87e-051031216CID000005345
DrugRutin

SLC2A9 SLCO2B1 SLCO1B3 SLCO1B1 PTGS2 TGFA

2.08e-051051216ctd:D012431
Drugrepaglinide

SLCO2B1 SLCO1B3 SLCO1B1

2.34e-05111213ctd:C072379
DrugNSC740136

SLC2A9 SLCO2B1 SLCO1B3 SLCO1B1 SLC2A5 TM4SF1

2.58e-051091216CID000003706
Drug3-iodothyronamine

SLCO4A1 SLC17A5 SLCO4C1 SLC16A7

2.76e-05331214ctd:C487948
DrugSQ 33,552

TBXA2R PTGS2

2.80e-0521212CID009576908
DrugSQ 33,261

TBXA2R PTGS2

2.80e-0521212CID009576907
Drugprostaglandin F1

PTGS2 PTGR1

2.80e-0521212ctd:C100006
Drug(5-(3-(4-(2-bromo-5-fluorophenoxy)piperidin-1-yl)isoxazol-5-yl)-2H-tetrazol-2-yl)acetic acid

SLCO1B3 SLCO1B1

2.80e-0521212ctd:C561635
Drugglimepiride

SLCO2B1 SLCO1B3 SLCO1B1

3.11e-05121213ctd:C057619
DrugAH23848B

TBXA2R PTGS2 CCKBR SLCO2A1

3.50e-05351214CID005310999
Drug1,2,5,6-dibenzanthracene

TBXA2R TMEM88 SLC2A9 SLCO2B1 VASN DDIAS HHIP RNF167 SLC10A2 SLC16A5 NRXN1 PTGR1 SLC5A6 SLC16A7 HYDIN

3.84e-0583712115ctd:C026486
DrugCholic Acid

SLCO2B1 SLCO1B3 SLCO1B1 PTGS2 SLC10A2

5.00e-05751215ctd:D019826
DrugPyruvic acid

SLC16A5 SLC16A4 SLC16A7

5.11e-05141213DB00119
DrugBiotin

TPR SLC5A6 HERC4

6.36e-05151213ctd:D001710
DrugBudesonide

SLCO2B1 SLCO1B3 SLCO1B1 PTGS2 PLA2G4A

6.82e-05801215ctd:D019819
DrugOctopamina

TBXA2R PTGS2

8.37e-0531212CID005311213
DrugEstropipate [7280-37-7]; Up 200; 9.2uM; MCF7; HT_HG-U133A

DOCK3 SIPA1 SLCO1B1 SLC2A5 SLC22A4 MYO15A TM4SF1

8.97e-0519712176068_UP
DrugDDDs

DOCK3 PTGS2 SLC5A5

9.43e-05171213CID000014360
Drugvinylidene chloride

NPR2 ANK2 SLC16A9 ACTR10 SLC6A19 SLCO4A1 PTGR2 ADGRL1 DDIAS SLC10A2 SLCO4C1 SLC16A5 PTGR1 SLC34A1 SLC18A1 SLC22A4 TM4SF1 MVP SLC16A7 SOAT1

9.71e-05147512120ctd:C029297
DrugPromazine hydrochloride [53-60-1]; Up 200; 12.4uM; MCF7; HT_HG-U133A

TBXA2R SZT2 SLC2A5 SLC5A5 SLC16A4 TLR5 TM4SF1

9.85e-0520012173833_UP
Drugchloride

ATP6V1A NPR2 SLC26A9 LBR APOL1 PTGS2 TGFA SLC5A5 ADK PTGR1 SLC34A1 SLC18A1 SLC5A6 PLA2G4A SOAT1 SLC16A10

1.12e-04102912116CID000000312
Drugflunixin

LBR SLCO1B1 PTGS2

1.13e-04181213CID000038081
Drug3alpha, 7beta-dihydroxy-5beta-cholan-24-oic acid

SLCO1B3 SLCO1B1 PTGS2 TGFA HSD3B7 SLC10A2 PKHD1

1.18e-042061217CID000005645
DrugMirex

SLC17A5 SLC16A4 SLC5A6 SLC16A7

1.23e-04481214ctd:D008917
Drugpentabromodiphenyl ether

CMKLR2 ATP6V1A SLCO2B1 SLC6A19 SLCO1B3 SLCO1B1 TMEM132B PTGS2 SLC5A5 SLC41A2 SLC17A5 HSD3B7 PTGR1 OR7D2 TLR5 PLA2G4A SLC16A7 SLC16A10

1.26e-04126612118ctd:C086401
Drughydride

DOCK3 ATP6V1A NPR2 STAG1 SLC26A9 LBR HSD3B7 PTGR1 SLC34A1 SLC18A1 GUCY2D SLC16A7 SOAT1 SDHC

1.43e-0483512114CID000000783
Drugpolydatin

SLC2A9 PTGS2 TGFA SLC22A4

1.45e-04501214ctd:C058229
Drugblack widow spider venom

ADGRL1 NRXN1

1.67e-0441212ctd:C038599
Drugalpha-latrotoxin

ADGRL1 NRXN1

1.67e-0441212ctd:C020763
Drugrifamycin SV

SLCO1B3 SLCO1B1

1.67e-0441212ctd:C023808
Drugmicrocystin-LF

SLCO1B3 SLCO1B1

1.67e-0441212ctd:C524165
Druglatanoprost

SLCO2B1 SLCO2A1

1.67e-0441212ctd:C072042
DrugNiflumic Acid

PTGS2 PLA2G4A

1.67e-0441212DB04552
DrugTaurocholic Acid

SLCO2B1 SLCO1B3 SLCO1B1 PTGS2 SLC10A2

1.79e-04981215ctd:D013656
Diseaseuric acid measurement

SLC2A9 SLC16A9 HLA-DQB1 ARL6IP5 PTGR2 SLCO1B1 SLC10A2 SLC22A4 GUCY2D HERC4 SOAT1 SLC16A10

4.05e-0661011312EFO_0004761
Diseasearachidonoylcarnitine (C20:4) measurement

SLC16A9 SLCO1B1 SLC22A4

1.17e-05121133EFO_0800544
Diseaseglycolithocholate sulfate measurement

SLCO1B1 SLC10A2

1.45e-0521132EFO_0800258
DiseaseHYPERBILIRUBINEMIA, ROTOR TYPE, DIGENIC

SLCO1B3 SLCO1B1

1.45e-0521132C4016905
DiseaseRotor Syndrome

SLCO1B3 SLCO1B1

1.45e-0521132C0220991
DiseaseRotor syndrome

SLCO1B3 SLCO1B1

1.45e-0521132cv:C0220991
DiseaseHYPERBILIRUBINEMIA, ROTOR TYPE

SLCO1B3 SLCO1B1

1.45e-0521132237450
Diseasedihomo-linolenoylcarnitine (C20:3n3 or 6) measurement

SLC16A9 SLCO1B1 SLC22A4

1.52e-05131133EFO_0800547
Diseasetaurolithocholate 3-sulfate measurement

SLCO1B1 SLC10A2 PLA2G4A

1.52e-05131133EFO_0021036
DiseaseGlycodeoxycholate sulfate measurement

SLCO1B1 SLC10A2

4.35e-0531132EFO_0022098
Diseasenon-melanoma skin carcinoma

HLA-DQB1 ACTR10 DEFB136 SLC10A2 MICA MYO15A OR2H2

7.48e-052651137EFO_0009260
Diseaselongitudinal BMI measurement, non-small cell lung carcinoma

SLC37A3 SLC16A7

8.68e-0541132EFO_0003060, EFO_0005937
Diseasepancreatic cancer (implicated_via_orthology)

CCKBR TGFA

8.68e-0541132DOID:1793 (implicated_via_orthology)
Diseasetaurodeoxycholic acid 3-sulfate measurement

SLCO1B1 SLC10A2

8.68e-0541132EFO_0800386
Diseaseglycodeoxycholate 3-sulfate measurement

SLCO1B1 SLC10A2

8.68e-0541132EFO_0800385
Diseasebilirubin metabolic disorder (implicated_via_orthology)

SLCO1B3 SLCO1B1

1.44e-0451132DOID:2741 (implicated_via_orthology)
Diseaseurate measurement

DOCK3 SLC2A9 SLC16A9 HLA-DQB1 ARL6IP5 SLCO1B1 NRXN1 TGFBRAP1 PKHD1 PLA2G4A HERC4 SLC16A10

1.68e-0489511312EFO_0004531
DiseaseMHC class I polypeptide-related sequence B measurement

HLA-DQB1 SLCO1B1 MICA

2.06e-04301133EFO_0008234
DiseaseCurling Ulcer

PTGS2 PLA2G4A

2.16e-0461132C0010474
Diseasebilirubin metabolic disorder (is_implicated_in)

SLCO1B3 SLCO1B1

2.16e-0461132DOID:2741 (is_implicated_in)
DiseaseDuodenal Ulcer

PTGS2 PLA2G4A

2.16e-0461132C0013295
Diseasetaurocholenate sulfate measurement

SLCO1B1 SLC10A2

2.16e-0461132EFO_0800277
Diseaseexcessive daytime sleepiness measurement

SLC2A9 SLC24A3 TMEM132B

2.74e-04331133EFO_0007875
DiseaseThyroid Gland Follicular Adenoma

TPR PTGS2 SLC5A5

3.27e-04351133C0151468
DiseaseThyroid Neoplasm

TPR PTGS2 SLC5A5

3.86e-04371133C0040136
Diseasedeoxycholic acid glucuronide measurement

SLCO1B3 SLCO1B1

4.01e-0481132EFO_0800575
Diseaseacetylcarnitine measurement

SLC16A9 SLC22A4

4.01e-0481132EFO_0021038
Diseasebutyrylcarnitine measurement

SLC16A9 SLC22A4

4.01e-0481132EFO_0020010
DiseaseCognition Disorders

PTGS2 SLC10A2 SLC4A10

4.18e-04381133C0009241
Diseaselung cancer (implicated_via_orthology)

TPR PTGS2

5.14e-0491132DOID:1324 (implicated_via_orthology)
DiseaseX-11381 measurement

SLC16A9 SLC22A4

5.14e-0491132EFO_0021228
Diseasehexadecenedioate (C16:1-DC) measurement

SLCO1B3 SLCO1B1

5.14e-0491132EFO_0800562
Diseaseliver cancer (is_marker_for)

SLCO2B1 SLCO1B1

5.14e-0491132DOID:3571 (is_marker_for)
DiseaseX-21467 measurement

SLCO1B3 SLCO1B1

5.14e-0491132EFO_0020007
DiseaseAsthma, Occupational

PTGS2 PLA2G4A

6.41e-04101132C0264423
Diseasecervical carcinoma, Cervical Intraepithelial Neoplasia Grade 2/3

HLA-DQB1 MICA

6.41e-04101132EFO_0001061, EFO_1000166
DiseaseThyroid carcinoma

TPR PTGS2 SLC5A5

6.46e-04441133C0549473
Diseasesleep duration, triglyceride measurement

STAG1 DEFB136 TMEM132B SLC5A6

6.98e-041041134EFO_0004530, EFO_0005271
Diseasetyrosine measurement

NPR2 SLCO1B1 TM9SF2 SLC16A10

6.98e-041041134EFO_0005058
Diseasegastrointestinal stromal tumor (is_implicated_in)

SLCO1B3 SDHC

7.82e-04111132DOID:9253 (is_implicated_in)
Diseaseaspirin-induced respiratory disease (is_implicated_in)

TBXA2R HLA-DQB1

7.82e-04111132DOID:0080822 (is_implicated_in)
Diseasepneumonia

HLA-DQB1 TM9SF2 MICA

7.84e-04471133EFO_0003106
Diseasehexanoylcarnitine measurement

SLC16A9 SLC22A4

9.36e-04121132EFO_0021040
DiseasePapilloma

PTGS2 TGFA

9.36e-04121132C0030354
DiseasePapillomatosis

PTGS2 TGFA

9.36e-04121132C0205875
DiseasePapilloma, Squamous Cell

PTGS2 TGFA

9.36e-04121132C0205874
Diseasecerotoylcarnitine (C26) measurement

ST3GAL3 SLC22A4

1.10e-03131132EFO_0800542
Diseaseglycochenodeoxycholate glucuronide (1) measurement

SLCO1B3 SLCO1B1

1.10e-03131132EFO_0800474
DiseaseAsthma, Aspirin-Induced

TBXA2R PTGS2

1.10e-03131132C1319853
Diseaseage at menopause

SLCO4A1 PTGR1 SLC18A1 FANCI TGFBRAP1 CHD6

1.11e-033021136EFO_0004704
Diseasetestosterone measurement

DOCK3 ANK2 SLC16A9 STAG1 SLCO1B3 SLC24A3 SLCO1B1 NRXN1 SLC34A1 TGFBRAP1 MYO15A HERC4 SOAT1

1.20e-03127511313EFO_0004908
Diseaseasymmetric dimethylarginine measurement

SLC24A3 MTHFS

1.28e-03141132EFO_0010463
Diseaserheumatoid arthritis (is_implicated_in)

HLA-DQB1 PTGS2 SLC22A4

1.45e-03581133DOID:7148 (is_implicated_in)
Diseaseamyotrophic lateral sclerosis, age at onset

ST3GAL3 SLC18A1

1.48e-03151132EFO_0004847, MONDO_0004976
DiseaseBlood Platelet Disorders

TBXA2R PLA2G4A

1.68e-03161132C0005818
Diseasesarcoidosis (is_implicated_in)

HLA-DQB1 PTGS2

1.68e-03161132DOID:11335 (is_implicated_in)
DiseaseDermatitis

DSG1 PLA2G4A

1.68e-03161132C0011603
Diseasetotal blood protein measurement

STAG1 HLA-DQB1 SLCO1B1 SLC18A1 PKHD1 SLC37A4 HYDIN

1.75e-034491137EFO_0004536
Diseasecystic fibrosis (is_marker_for)

PTGS2 DEFB4A TLR5

1.75e-03621133DOID:1485 (is_marker_for)
Diseasediabetic neuropathy (biomarker_via_orthology)

PTGS2 HHIP

1.90e-03171132DOID:9743 (biomarker_via_orthology)
DiseaseGraves disease, thyrotoxic periodic paralysis

HLA-DQB1 MICA

1.90e-03171132EFO_0004237, MONDO_0019201
DiseaseProfound Mental Retardation

STAG1 ADK NRXN1 SLC4A10

2.04e-031391134C0020796
DiseaseMental Retardation, Psychosocial

STAG1 ADK NRXN1 SLC4A10

2.04e-031391134C0025363
DiseaseMental deficiency

STAG1 ADK NRXN1 SLC4A10

2.04e-031391134C0917816
DiseaseOral Submucous Fibrosis

PTGS2 MICA

2.14e-03181132C0029172
Diseasemelanoma

SIPA1 TMEM132B PTGS2 SLC5A5 SLC17A5

2.71e-032481135C0025202
DiseaseAutoimmune Hepatitis

HLA-DQB1 MICA

2.91e-03211132EFO_0005676
DiseaseHbA1c measurement, response to sulfonylurea

SLC16A9 SLCO1B1

2.91e-03211132EFO_0004541, EFO_0007922
Diseaseresponse to angiotensin-converting enzyme inhibitor

SLCO4A1 HHIP NRXN1

3.38e-03781133EFO_0005325
DiseaseLiver carcinoma

VASN PTGS2 TGFA SLC5A5 HHIP FANCI MICA

3.43e-035071137C2239176
DiseaseIntrahepatic Cholangiocarcinoma

PTGS2 SLC5A5

3.80e-03241132C0345905
DiseaseExtrahepatic Cholangiocarcinoma

PTGS2 SLC5A5

3.80e-03241132C3805278

Protein segments in the cluster

PeptideGeneStartEntry
LFGMGNPLLDISAVV

ADK

26

P55263
FGTMLIPPFTLIGSL

ABCA9

1166

Q8IUA7
FNMEFLGPCGLRLVG

HSD3B7

271

Q9H2F3
ATQGLSRAGLPFGLM

ADGRL1

21

O94910
FGVELGPSLMNLIAG

NPR2

321

P20594
TLLPNLMGTFIFGTV

CCKBR

111

P32239
LFIFLMPLPGVFGGI

DEFB4A

11

O15263
SMGSPFLLAGLIGGA

FLRT2

536

O43155
LLSFMGLFICGETPG

GKN3P

166

P0CG01
ENLVVIGGTSMLPGF

ACTR10

301

Q9NZ32
MGGLGFIILDRSNAP

OSTC

96

Q9NRP0
FLGGGEGLLLVVMAF

OR4N4C

106

A0A096LPK9
FILLGFTTDPGMQLG

OR9G1

11

Q8NH87
GVPGVFLIMFGLPVF

LBR

211

Q14739
MGLGPVFLLLAGIFP

MICA

1

Q29983
VMLNGFGGDAPTLRL

ANK2

1246

Q01484
GLVELGFILMDSYGP

FANCI

381

Q9NVI1
GVAFSLGFTLGPMLG

MFSD10

181

Q14728
MFFAGLGNSLGPPIV

SLC16A9

436

Q7RTY1
TGGLDLIFMPGLGFD

MTHFS

126

P49914
NSMIIFGPFLSILGS

OR11H6

221

Q8NGC7
MVNQSSTPGFLLLGF

OR2H2

1

O95918
GGSLDGFLLTPITMS

OR2T1

201

O43869
FLGLGLSGVVPTMHF

ADIPOR1

271

Q96A54
SDGGGFPLSGLLMVL

MAGEB17

191

A8MXT2
TILEFNLFGIPMVGA

MGAM2

591

Q2M2H8
VFLGFLLVVGMGLAG

GUCY2D

466

Q02846
RAQFLGLLSALPMFG

MYO15A

3401

Q9UKN7
LGGSIDGFLLTPVTM

OR2T7

141

P0C7T2
LLLFAVGFIMAGTPL

OR3A2

206

P47893
GSVFMPSAFILIGIP

OR52A5

6

Q9H2C5
FLGGGEGLLLVVMAF

OR4N2

106

Q8NGD1
FLGGGEGLLLVVMAF

OR4N4

106

Q8N0Y3
AQFIGPLVFGGMNLT

PDCL3

176

Q9H2J4
KIFPSDMLGFQGIGL

DDIAS

871

Q8IXT1
SLLGIPFMQVAAGGA

HERC4

186

Q5GLZ8
DPAPGFSMLLFGVSL

NRG2

96

O14511
MGFITGLGLAFNLQP

SLC16A7

116

O60669
FAVGQEVFGLVPGLM

PTGS2

271

P35354
ILPGILNDTLRFGMF

KLHL40

301

Q2TBA0
DMTVFSGLFVGGLPP

NRXN1

146

Q9ULB1
GGSIDGFLLTPVTMQ

OR2T27

151

Q8NH04
FILLGFTTDPGMQLG

OR9G9

11

P0C7N8
AIVGPQLSMFASGLF

MFSD11

71

O43934
MTIGFALQLLGGPFQ

GAL3ST4

26

Q96RP7
INPGLFIMTPAGVFL

CXXC5

216

Q7LFL8
FGPAGIGLLIMGFLV

DSG1

546

Q02413
LFNTAFGLLGMGPEG

MVP

841

Q14764
GIPDVIMGITFLAAG

SLC24A3

506

Q9HC58
MVGVGTPFGALLAFV

SLC34A1

541

Q06495
LMANVGGFLAGLPFS

SLC37A4

371

O43826
MLSGIGGFVLGLIFL

HLA-DQB1

231

P01920
SSLAGGEYIIPLFGM

HYDIN

5006

Q4G0P3
FIPGMIGPFLGVTLV

DOCK3

1091

Q8IZD9
PLTGLVGFPAGFATM

CHD6

2491

Q8TD26
MTEGVLPGLYLGNFI

DUSP15

1

Q9H1R2
GVSLFGMSALLLPGN

SDHC

81

Q99643
SGILTLVGMGLAPFT

APOL1

186

O14791
LVGMGLAPFTEGGSL

APOL1

191

O14791
GLGSPLMGLTFINAL

SLC25A29

61

Q8N8R3
GFPPQTATGTLMLFL

CDH26

476

Q8IXH8
RPLLIGGFGLMGLFF

SLC2A9

381

Q9NRM0
LFLTLLDMAQGFRGP

HYAL1

11

Q12794
FLVILLPSGKGMFGN

DEFB136

11

Q30KP8
MLPAGGILVFLTGQA

DHX37

466

Q8IY37
GMIGPAVFLVAAGFI

SLC17A5

371

Q9NRA2
LGITNTFATIPGMVG

SLC17A5

426

Q9NRA2
GILTLFFPESLGMTL

SLC22A4

501

Q9H015
SLLGSLMVGLSGVFP

SLC39A13

71

Q96H72
GVGLLELGFMTLSIF

CD37

251

P11049
GFPGSQTLQLSLFML

OR6F1

16

Q8NGZ6
TVGMPGLTAYFGLLE

PTGR1

121

Q14914
GFLCQFGIMPLTGFI

SLC10A2

71

Q12908
GQPVTFTDIFGMLIG

PLA2G4A

286

P47712
TQMLGGALGLALFPS

OR10Q1

146

Q8NGQ4
IMLFLTTGLFAALGP

OR14I1

246

A6ND48
ALPGGIILMELAFQG

SZT2

2986

Q5T011
GGGAFMIPFLILLVL

SLC6A19

66

Q695T7
LFMIFQIGVLGFGPT

SOAT1

226

P35610
IPALLGGTTMELFFT

TMEM132B

206

Q14DG7
LLGPVIMGVGLFVFI

TMEM200B

116

Q69YZ2
KVFGPLIMGIGIFLF

TMEM200C

166

A6NKL6
GGSIQVPQGMAFALL

SLC26A9

81

Q7LBE3
GPVLQAAISIFGMVG

SLC5A6

421

Q9Y289
AAISIFGMVGGPLLG

SLC5A6

426

Q9Y289
SMFPFGGFIGSLLVG

SLC2A5

76

P22732
SIVGFLSPFNMILGG

ARL6IP5

56

O75915
PFTGIVGLLVLAMGA

RNF167

176

Q9H6Y7
AGPAFMQFLTLLGDV

SIPA1

356

Q96FS4
AFTLIGLPFNNGLMG

ST3GAL3

281

Q11203
GMAFALLASVPPVFG

SLC26A10

41

Q8NG04
PFLLAGFGTVSAGMV

SLC41A2

166

Q96JW4
GLQVTVPFMFAGLGL

SLC41A3

66

Q96GZ6
FMTGVLGVFPLLGII

OR7D2

201

Q96RA2
GVFLGPIFGDMLATA

PKHD1

886

P08F94
ITGMLEFSLFGIPLV

SI

616

P14410
FRGGMLTNARLLFGP

MRPS2

171

Q9Y399
PDGFLYIILGDGMIT

HHIP

361

Q96QV1
AMIGPIIGFTLGSLF

SLCO1B1

216

Q9Y6L6
GVLLMGTGSLVFALP

SLCO4A1

176

Q96BD0
VMQAGIPLSTGLAFL

CMKLR2

281

P46091
GLFGFSVGPVAMELA

SLC49A3

351

Q6UXD7
VNLPAAALGMLFGGI

SLCO2A1

371

Q92959
MVPSAGQLALFALGI

TGFA

1

P01135
FLLAGPGGLGMFATV

TGFBRAP1

221

Q8WUH2
TMGLLPGLGSAFLYQ

SLC16A4

116

O15374
GFSNIFLRPLAGLMA

SLC16A5

281

O15375
LLMTVTGFFIGGPSN

SLC37A3

386

Q8NCC5
SFTVMGVISGPLLGA

SLC5A5

416

Q92911
GVISGPLLGAFILGM

SLC5A5

421

Q92911
IMFVAQTLLGVGGVP

SLCO2B1

191

O94956
VISLDGFFMLLFPGT

TAS2R9

61

Q9NYW1
ASQGGLGMYETPLFL

TPR

2186

P12270
MIGLGALVFSLPQFF

SLCO4C1

181

Q6ZQN7
ALLGTPVGGLLMAFQ

TIMMDC1

196

Q9NPL8
MLLTLAGGALFFPGL

TLCD3A

1

Q8TBR7
MSPVITFGGLLGEAT

SLC4A10

521

Q6U841
SLNAIGMIGPVIGFA

SLCO1B3

211

Q9NPD5
GMIGPVIGFALGSLF

SLCO1B3

216

Q9NPD5
LMTGGREGLQPLVFN

STAG1

806

Q8WVM7
GTILLPAVTMLGFGF

TMEM88

51

Q6PEY1
LSVELGPGIMGAIFD

ATP6V1A

86

P38606
SGIVGGGLLMLLPAF

TM4SF1

51

P30408
MLDAGSFAGLPGLQL

VASN

66

Q6EMK4
MGGILPFGCIFIQLF

TM9SF2

526

Q99805
VMIFFGLSPLLLGAA

TBXA2R

111

P21731
DLLLGVVLMAGPVFG

TLR5

6

O60602
LSYFLGAIGMPGLTS

PTGR2

126

Q8N8N7
TVFMLFSGQGSLLQP

TMEM33

171

P57088
LALGLLVGAPFGSVM

SLC18A1

236

P54219
VSQAIGFLLGFMSIP

SLC16A10

416

Q8TF71