Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyCellularComponentcalcium- and calmodulin-dependent protein kinase complex

CAMK2B CAMK2G

5.58e-055502GO:0005954
DomainCaMKII_AD

CAMK2B CAMK2G

4.03e-054492PF08332
DomainCa/CaM-dep_prot_kinase-assoc

CAMK2B CAMK2G

4.03e-054492IPR013543
Domain-

CAMK2B CAMK2G

5.16e-04134923.10.450.50
DomainNTF2-like_dom

CAMK2B CAMK2G

6.93e-0415492IPR032710
DomainSH2

INPP5D SH3BP2 SLA

2.36e-03101493PF00017
DomainHelicase_C

BLM SHPRH CHD7

2.78e-03107493PF00271
DomainHELICc

BLM SHPRH CHD7

2.78e-03107493SM00490
DomainHelicase_C

BLM SHPRH CHD7

2.86e-03108493IPR001650
DomainHELICASE_CTER

BLM SHPRH CHD7

2.93e-03109493PS51194
DomainHELICASE_ATP_BIND_1

BLM SHPRH CHD7

2.93e-03109493PS51192
DomainDEXDc

BLM SHPRH CHD7

2.93e-03109493SM00487
DomainHelicase_ATP-bd

BLM SHPRH CHD7

3.01e-03110493IPR014001
DomainSH2

INPP5D SH3BP2 SLA

3.01e-03110493SM00252
DomainSH2

INPP5D SH3BP2 SLA

3.09e-03111493PS50001
DomainSH2

INPP5D SH3BP2 SLA

3.16e-03112493IPR000980
Domain-

INPP5D SH3BP2 SLA

3.16e-031124933.30.505.10
DomainSNF2_N

SHPRH CHD7

3.18e-0332492IPR000330
DomainSNF2_N

SHPRH CHD7

3.18e-0332492PF00176
DomainDNA/RNA_helicase_DEAH_CS

BLM CHD7

3.80e-0335492IPR002464
DomainDEAH_ATP_HELICASE

BLM CHD7

4.46e-0338492PS00690
DomainGPCR_Rhodpsn_7TM

MAS1L GPR142 ACKR3 CYSLTR1 OR52H1 CHRM4

7.85e-03670496IPR017452
Domain7tm_1

MAS1L GPR142 ACKR3 CYSLTR1 OR52H1 CHRM4

8.24e-03677496PF00001
PathwayREACTOME_CREB1_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_CAMKII_CAMKK_CAMKIV_CASCASDE

CAMK2B CAMK2G

2.29e-048412M10546
PathwayREACTOME_CAMK_IV_MEDIATED_PHOSPHORYLATION_OF_CREB

CAMK2B CAMK2G

3.66e-0410412M26910
PathwayREACTOME_ION_HOMEOSTASIS

CAMK2B CAMK2G ATP2B1

5.11e-0454413M27460
PathwayREACTOME_ION_HOMEOSTASIS

CAMK2B CAMK2G ATP2B1

5.11e-0454413MM15202
PathwayREACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES

CAMK2B CAMK2G ATP2B1

5.39e-0455413M971
PathwayREACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES

CAMK2B CAMK2G ATP2B1

5.99e-0457413MM15643
PathwayKEGG_MEDICUS_VARIANT_AMPLIFIED_EGFR_TO_PLCG_CAMK_SIGNALING_PATHWAY

CAMK2B CAMK2G

7.35e-0414412M47386
PathwayKEGG_MEDICUS_VARIANT_AMPLIFIED_PDGFR_TO_PLCG_CAMK_SIGNALING_PATHWAY

CAMK2B CAMK2G

7.35e-0414412M47388
PathwayKEGG_MEDICUS_REFERENCE_EGF_EGFR_PLCG_CAMK_SIGNALING_PATHWAY

CAMK2B CAMK2G

8.46e-0415412M47385
PathwayWP_CALCIUM_REGULATION_IN_CARDIAC_CELLS

CAMK2B CAMK2G ATP2B1 CHRM4

8.52e-04147414MM15854
PathwayWP_CALCIUM_REGULATION_IN_CARDIAC_CELLS

CAMK2B CAMK2G ATP2B1 CHRM4

9.41e-04151414M39329
PathwayKEGG_MEDICUS_REFERENCE_PDGF_PDGFR_PLCG_CAMK_SIGNALING_PATHWAY

CAMK2B CAMK2G

1.09e-0317412M47387
PathwayKEGG_MEDICUS_REFERENCE_CA2_CAM_CAMK_SIGNALING_PATHWAY

CAMK2B CAMK2G

1.37e-0319412M47957
PathwayREACTOME_INTERFERON_GAMMA_SIGNALING

CAMK2B CAMK2G

1.37e-0319412MM15473
PathwayREACTOME_RAS_ACTIVATION_UPON_CA2_INFLUX_THROUGH_NMDA_RECEPTOR

CAMK2B CAMK2G

1.52e-0320412M17670
PathwayREACTOME_ION_CHANNEL_TRANSPORT

BEST1 CAMK2B CAMK2G ATP2B1

1.66e-03176414MM15718
PathwayREACTOME_UNBLOCKING_OF_NMDA_RECEPTORS_GLUTAMATE_BINDING_AND_ACTIVATION

CAMK2B CAMK2G

1.67e-0321412M838
PathwayREACTOME_NEGATIVE_REGULATION_OF_NMDA_RECEPTOR_MEDIATED_NEURONAL_TRANSMISSION

CAMK2B CAMK2G

1.67e-0321412M27944
PathwayKEGG_CALCIUM_SIGNALING_PATHWAY

CAMK2B CYSLTR1 CAMK2G ATP2B1

1.73e-03178414M2890
PathwayREACTOME_UNBLOCKING_OF_NMDA_RECEPTORS_GLUTAMATE_BINDING_AND_ACTIVATION

CAMK2B CAMK2G

1.84e-0322412MM15104
PathwayREACTOME_ION_CHANNEL_TRANSPORT

BEST1 CAMK2B CAMK2G ATP2B1

1.91e-03183414M997
PathwayWP_VITAMIN_D_RECEPTOR_PATHWAY

CLPTM1L TNFAIP3 HSD17B2 ATP2B1

1.99e-03185414M39718
PathwayREACTOME_HSF1_DEPENDENT_TRANSACTIVATION

CAMK2B CAMK2G

2.01e-0323412MM14953
PathwayKEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_ATP2B3_TO_ANGIOTENSIN_ALDOSTERONE_SIGNALING_PATHWAY

CAMK2B CAMK2G

2.01e-0323412M47512
PathwayREACTOME_LONG_TERM_POTENTIATION

CAMK2B CAMK2G

2.01e-0323412M27949
PathwayREACTOME_G_ALPHA_I_SIGNALLING_EVENTS

ACKR3 CAMK2B CAMK2G CCL25 CHRM4

2.06e-03314415M600
PathwayKEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_CACNA1D_H_TO_ANGIOTENSIN_ALDOSTERONE_SIGNALING_PATHWAY

CAMK2B CAMK2G

2.19e-0324412M47509
PathwayKEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_KCNJ5_TO_ANGIOTENSIN_ALDOSTERONE_SIGNALING_PATHWAY

CAMK2B CAMK2G

2.37e-0325412M47510
PathwayKEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_ATP1A1_TO_ANGIOTENSIN_ALDOSTERONE_SIGNALING_PATHWAY

CAMK2B CAMK2G

2.37e-0325412M47511
Pubmed

Calcineurin-independent regulation of plasma membrane Ca2+ ATPase-4 in the vascular smooth muscle cell cycle.

CAMK2B CAMK2G ATP2B1

2.48e-07951312660151
Pubmed

The role of calcium and calcium/calmodulin-dependent kinases in skeletal muscle plasticity and mitochondrial biogenesis.

CAMK2B CAMK2G

2.11e-06251215294044
Pubmed

A role for CaMKII in T cell memory.

CAMK2B CAMK2G

2.11e-06251210693762
Pubmed

Identification of novel human tumor cell-specific CaMK-II variants.

CAMK2B CAMK2G

6.32e-0635129060999
Pubmed

Cloning and quantitative determination of the human Ca2+/calmodulin-dependent protein kinase II (CaMK II) isoforms in human beta cells.

CAMK2B CAMK2G

6.32e-06351210819240
Pubmed

Calcium/calmodulin kinase II-dependent acetylcholine receptor cycling at the mammalian neuromuscular junction in vivo.

CAMK2B CAMK2G

6.32e-06351220844140
Pubmed

KN-93 inhibition of G protein signaling is independent of the ability of Ca2+/calmodulin-dependent protein kinase II to phosphorylate phospholipase Cbeta3 on 537-Ser.

CAMK2B CAMK2G

6.32e-06351211325525
Pubmed

Calcium/calmodulin-dependent protein kinase II and calmodulin: regulators of the meiotic spindle in mouse eggs.

CAMK2B CAMK2G

6.32e-0635129882483
Pubmed

Induction of endotoxin tolerance in vivo inhibits activation of IRAK4 and increases negative regulators IRAK-M, SHIP-1, and A20.

INPP5D TNFAIP3

1.26e-05451221934070
Pubmed

Developmental expression of the CaM kinase II isoforms: ubiquitous gamma- and delta-CaM kinase II are the early isoforms and most abundant in the developing nervous system.

CAMK2B CAMK2G

1.26e-05451210381553
Pubmed

IGF-II/mannose-6-phosphate receptor signaling induced cell hypertrophy and atrial natriuretic peptide/BNP expression via Galphaq interaction and protein kinase C-alpha/CaMKII activation in H9c2 cardiomyoblast cells.

IGF2R CAMK2G

1.26e-05451218434368
Pubmed

Cadmium activates CaMK-II and initiates CaMK-II-dependent apoptosis in mesangial cells.

CAMK2B CAMK2G

1.26e-05451217367784
Pubmed

[Molecular mechanisms of the intracellular localizations of Ca2+/calmodulin-dependent protein kinase II isoforms, and their physiological functions].

CAMK2B CAMK2G

1.26e-05451211889801
Pubmed

Densin-180 forms a ternary complex with the (alpha)-subunit of Ca2+/calmodulin-dependent protein kinase II and (alpha)-actinin.

CAMK2B CAMK2G

2.10e-05551211160423
Pubmed

Calmodulin kinase II attenuation of gene transcription by preventing cAMP response element-binding protein (CREB) dimerization and binding of the CREB-binding protein.

CAMK2B CAMK2G

2.10e-05551211013247
Pubmed

Ca2+/calmodulin-dependent protein kinase IIdelta and protein kinase D overexpression reinforce the histone deacetylase 5 redistribution in heart failure.

CAMK2B CAMK2G

2.10e-05551218218981
Pubmed

Aberrant calcium/calmodulin-dependent protein kinase II (CaMKII) activity is associated with abnormal dendritic spine morphology in the ATRX mutant mouse brain.

CAMK2B CAMK2G

2.10e-05551221209221
Pubmed

PTENα Modulates CaMKII Signaling and Controls Contextual Fear Memory and Spatial Learning.

CAMK2B CAMK2G

2.10e-05551228636948
Pubmed

Comparative analyses of the three-dimensional structures and enzymatic properties of alpha, beta, gamma and delta isoforms of Ca2+-calmodulin-dependent protein kinase II.

CAMK2B CAMK2G

2.10e-05551214722083
Pubmed

Transition from reversible to persistent binding of CaMKII to postsynaptic sites and NR2B.

CAMK2B CAMK2G

2.10e-05551216436603
Pubmed

Activity of muscarinic, galanin and cannabinoid receptors in the prodromal and advanced stages in the triple transgenic mice model of Alzheimer's disease.

PSEN1 CHRM4

2.10e-05551227223629
Pubmed

Multiple kinases regulate mafA expression in the pancreatic beta cell line MIN6.

CAMK2B CAMK2G

3.15e-05651218948074
Pubmed

Rad and Rad-related GTPases interact with calmodulin and calmodulin-dependent protein kinase II.

CAMK2B CAMK2G

4.41e-0575129115241
Pubmed

Ca(2+)/CaM-dependent kinases: from activation to function.

CAMK2B CAMK2G

5.87e-05851211264466
Pubmed

Structure of the CaMKIIdelta/calmodulin complex reveals the molecular mechanism of CaMKII kinase activation.

CAMK2B CAMK2G

5.87e-05851220668654
Pubmed

CaMKII Signaling Stimulates Mef2c Activity In Vitro but Only Minimally Affects Murine Long Bone Development in vivo.

CAMK2B CAMK2G

9.42e-051051228361052
Pubmed

The presence and activation of two essential transcription factors (cAMP response element-binding protein and cAMP-dependent transcription factor ATF1) in the two-cell mouse embryo.

CAMK2B CAMK2G

9.42e-051051219776387
Pubmed

Lysosomal proteolysis and autophagy require presenilin 1 and are disrupted by Alzheimer-related PS1 mutations.

IGF2R PSEN1

9.42e-051051220541250
Pubmed

Comprehensive analysis of common genetic variation in 61 genes related to steroid hormone and insulin-like growth factor-I metabolism and breast cancer risk in the NCI breast and prostate cancer cohort consortium.

IGF2R HSD17B2 PRLR

1.01e-046151320634197
Pubmed

90-kDa ribosomal S6 kinase is a direct target for the nuclear fibroblast growth factor receptor 1 (FGFR1): role in FGFR1 signaling.

SH3BP2 SLA

1.15e-041151215117958
Pubmed

Expression of Ca2+/calmodulin-dependent protein kinase types II and IV, and reduced DNA synthesis due to the Ca2+/calmodulin-dependent protein kinase inhibitor KN-62 (1-[N,O-bis(5-isoquinolinesulfonyl)-N-methyl-L-tyrosyl]-4-phenyl piperazine) in small cell lung carcinoma.

CAMK2B CAMK2G

1.38e-04125128615909
Pubmed

Developmental rearrangements of cortical glutamate-NMDA receptor binding sites in late human gestation.

CAMK2B CAMK2G

1.38e-04125128665664
Pubmed

Activation of peripheral NMDA receptors contributes to human pain and rat afferent discharges evoked by injection of glutamate into the masseter muscle.

CAMK2B CAMK2G

1.38e-041251212815021
Pubmed

Presence of three distinct molecular species of Gi protein alpha subunit. Structure of rat cDNAs and human genomic DNAs.

ACKR3 CCL25 CHRM4

1.86e-04755132834384
Pubmed

Ras-specific exchange factor GRF: oligomerization through its Dbl homology domain and calcium-dependent activation of Raf.

CAMK2B CAMK2G

1.90e-041451210373510
Pubmed

The NMDA receptor is coupled to the ERK pathway by a direct interaction between NR2B and RasGRF1.

CAMK2B CAMK2G

2.19e-041551214622581
Pubmed

Adjacent asparagines in the NR2-subunit of the NMDA receptor channel control the voltage-dependent block by extracellular Mg2+.

CAMK2B CAMK2G

2.19e-04155129481670
Pubmed

Skeletal Muscle-Specific Methyltransferase METTL21C Trimethylates p97 and Regulates Autophagy-Associated Protein Breakdown.

CAMK2B CAMK2G

2.50e-041651229719249
Pubmed

Motor protein-dependent transport of AMPA receptors into spines during long-term potentiation.

CAMK2B CAMK2G

3.18e-041851218311135
Pubmed

An unappreciated role for RNA surveillance.

KLK15 PSEN1 SH3BP2

4.60e-0410251314759258
Pubmed

Atrx deficiency induces telomere dysfunction, endocrine defects, and reduced life span.

IGF2R PRLR

6.19e-042551223563309
Pubmed

The HIV-1 envelope protein gp120 impairs B cell proliferation by inducing TGF-β1 production and FcRL4 expression.

BLM CYSLTR1 INPP5D

7.22e-0411951324162774
Pubmed

E-cadherin expression on multiple myeloma cells activates tumor-promoting properties in plasmacytoid DCs.

INPP5D TNFAIP3

7.78e-042851230277474
Pubmed

Mutations of the Transcriptional Corepressor ZMYM2 Cause Syndromic Urinary Tract Malformations.

BLM SLF2 CHD7

8.32e-0412551332891193
Pubmed

Investigation of genetic susceptibility factors for human longevity - a targeted nonsynonymous SNP study.

BLM TAF1C CHD7 TNFAIP3

1.15e-0331351420800603
Pubmed

Polymorphisms in the estrogen receptor 1 and vitamin C and matrix metalloproteinase gene families are associated with susceptibility to lymphoma.

IGF2R HSD17B2 PRLR

1.18e-0314151318636124
Pubmed

Transgenic mouse proteomics identifies new 14-3-3-associated proteins involved in cytoskeletal rearrangements and cell signaling.

CAMK2B CAMK2G ATP2B1

1.33e-0314751316959763
Pubmed

Quantitative trait loci predicting circulating sex steroid hormones in men from the NCI-Breast and Prostate Cancer Cohort Consortium (BPC3).

HSD17B2 PRLR

1.43e-033851219574343
Cytoband19p13.2

LRRC8E CCL25 ZNF653

2.14e-0322951319p13.2
Cytoband17q25.1

GPR142 NT5C

3.71e-038151217q25.1
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Myeloid|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

BEST1 IGF2R TNFAIP3 SLA ATP2B1

2.98e-06196515ff88e5b919b1be93159ad2200a7786d1c5272724
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW10-Neuronal-Interneuron|GW10 / Sample Type, Dataset, Time_group, and Cell type.

BEST1 ACKR3 ARNT2 CCL25

1.32e-05126514ec445ec097c9c45cd47b8cfa8c140df5b298695e
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Rxfp1_Eya1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

FAT1 OR52H1 HSD17B2 SLA

1.69e-05134514657ad905b40ec3f82acdef824431b8276d291ef7
ToppCell3'-Pediatric_IBD-SmallIntestine-Hematopoietic-T_cells-ILC3|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KDM4D TMPRSS3 TNFAIP3 SLA

3.46e-05161514584e44e6048c2678eb72cd23a86f48f2466c5da4
ToppCell3'-GW_trimst-2-SmallIntestine-Hematopoietic-T_cells-ILCP|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

BLM TMPRSS3 TNFAIP3 SLA

3.46e-051615146d9907e2949a742c0933128fde57832a9ca5f77c
ToppCellnormal_Lymph_Node-B_lymphocytes-Undetermined|normal_Lymph_Node / Location, Cell class and cell subclass

INPP5D CHD7 ATP2B1 NT5C

3.55e-0516251491ac35ae7fde411cd6a44e715a33dac62419cab8
ToppCell5'-GW_trimst-2-LargeIntestine-Hematopoietic-T_cells-ILCP|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

INPP5D TMPRSS3 PIGV SLA

4.69e-05174514c0204a0d0a979a489e8d30dc5396e99da14c119c
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW10-Neuronal-GABAergic_neurons|GW10 / Sample Type, Dataset, Time_group, and Cell type.

BEST1 ACKR3 ARNT2 CCL25

4.79e-05175514d4ff1f197ad4086286e86817cbff24fa718293fc
ToppCellfacs-Skin-Anagen-3m-Lymphocytic-T_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

INPP5D ARNT2 SLA CHRM4

5.01e-051775147853430fb0d1a18d835e8956777e0616c5d7d412
ToppCellfacs-Skin-Anagen-3m-Lymphocytic|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

INPP5D ARNT2 SLA CHRM4

5.01e-05177514395f005f019aabb18738d3a10a04c37f216deda3
ToppCellCOVID-19-B_cells-Activated_B_cells|COVID-19 / group, cell type (main and fine annotations)

CYSLTR1 INPP5D CHD7 ATP2B1

5.01e-05177514653bb62a3744d4024ab3186ee01d410ed62832a6
ToppCellfacs-Skin-Anagen-3m-Lymphocytic-nan|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

INPP5D ARNT2 SLA CHRM4

5.01e-051775149a5bf67a801826d094f679dd2189b62296c9694f
ToppCellPosterior_cortex-Hematopoietic-MICROGLIA|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

CYSLTR1 INPP5D TNFAIP3 SLA

5.23e-051795145122fc794509492afde4af8b1b76d51e3070ef05
ToppCelldroplet-Kidney-nan-21m-Lymphocytic|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYSLTR1 INPP5D TNFAIP3 SLA

5.23e-0517951421736ae288ea6113e2a5604fbda338fc6b2b94a8
ToppCellfacs-Trachea-24m-Hematologic|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

INPP5D SMOX SLA ATP2B1

5.58e-05182514a6162498a8a41a7fdf84d744e4203f99dfb284fa
ToppCellCOVID-19-kidney-CD-IC-A|kidney / Disease (COVID-19 only), tissue and cell type

DPY19L2 ARNT2 CRYBG3 PRLR

5.70e-051835145c7597a5b2bf6a481ca2c7e68560179214150fa0
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage-Monocyte-derived_macrophage_L.1.2.3.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SH3BP2 TNFAIP3 SLA ATP2B1

5.82e-05184514857ca1fc4de07b300839b22924211dc624453841
ToppCelldroplet-Lung-21m-Hematologic-lymphocytic-immature_innate_lymphoid_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CYSLTR1 ARNT2 SMOX SLA

6.20e-05187514fae08f34dc4b15352bd4d10bc6c924fe119b5d5e
ToppCelldroplet-Lung-21m-Hematologic-lymphocytic-immature_innate_lymphoid_cell-Ly6g5b+_T|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CYSLTR1 ARNT2 SMOX SLA

6.20e-05187514e6b140b9fb582abf07aa6ea9bc437de3ba0d6de1
ToppCellsaliva-Severe-critical_progression_d28-40-Myeloid-Monocytic-Classical_Monocyte-Mono_c1-CD14-CCL3|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

BEST1 TNFAIP3 SLA ATP2B1

6.59e-05190514212f0d9defcc3174e225cc3d90e7814e238794b6
ToppCellsaliva-Severe-critical_progression_d28-40-Myeloid-Monocytic|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

BEST1 TNFAIP3 SLA ATP2B1

6.73e-051915144d7f6216958fb202426b7a102e74682105ce7fca
ToppCellsaliva-Severe-critical_progression_d28-40-Myeloid-Monocytic-Classical_Monocyte|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

BEST1 TNFAIP3 SLA ATP2B1

6.73e-05191514e979f6768065b8b3e522d66999ca794d844eccb4
ToppCell11.5-Airway-Immune-Hematopoietic,_T_Cells|Airway / Age, Tissue, Lineage and Cell class

INPP5D TMPRSS3 TNFAIP3 SLA

7.01e-051935147c14bc481ed38378b9e6a85f768a1e526c5997e6
ToppCell367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_4|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)

CYSLTR1 CHD7 SETD7

7.12e-057051337e34ef782b253c43628d5bb2fe5e0294573d0ef
ToppCellsaliva-Severe-critical_progression_d28-40-Myeloid|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

BEST1 TNFAIP3 SLA ATP2B1

7.44e-051965146230b4a26770d30f1ab83345c087f03be1be0f9e
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Monocytic-Classical_Monocyte|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

BEST1 TNFAIP3 SLA ATP2B1

7.44e-05196514d9b5eaca4089d5337f1175a663418c9c675cdd87
ToppCellAdult-Immune|Adult / Lineage, Cell type, age group and donor

INPP5D SH3BP2 SLA ATP2B1

7.73e-051985149bfd7b88aa646eaf5eddb15cf985c7ca910cb35e
ToppCellMS-IIF-Lymphocyte-B-B_memory|IIF / Disease, condition lineage and cell class

CYSLTR1 CHD7 ATP2B1 NT5C

7.73e-05198514ae6f1d3ca7d7aa6f6f45b6b51aa8a967cadde017
ToppCell(1)_T_cell-(11)_Activated_CD4_T|(1)_T_cell / shred on Cell_type and subtype

CYSLTR1 TNFAIP3 CRYBG3 ATP2B1

7.73e-051985144b9ad91342f622c63e476d4f6a0ae5bf282a7ef5
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Myeloid|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

BEST1 TNFAIP3 SLA ATP2B1

7.89e-05199514da7cf363712ecec4fb90e3881eb585b7eea13fe7
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

BEST1 TNFAIP3 SLA ATP2B1

7.89e-051995149da8b48ec1c1c105fcbab6ae8f08166e7d5e8a35
DiseaseLiver Cirrhosis, Experimental

FAT1 IGF2R ACKR3 INPP5D HSD17B2 SLA PRLR

2.40e-04774487C0023893
Diseaseesophagus squamous cell carcinoma (is_marker_for)

CLPTM1L FAT1 TNFAIP3

2.41e-0474483DOID:3748 (is_marker_for)
Diseaseautosomal dominant intellectual developmental disorder (is_implicated_in)

CAMK2G ATP2B1

3.47e-0417482DOID:0060307 (is_implicated_in)
DiseaseAcute Confusional Senile Dementia

IGF2R PSEN1 INPP5D

5.68e-0499483C0546126
DiseaseAlzheimer's Disease, Focal Onset

IGF2R PSEN1 INPP5D

5.68e-0499483C0750900
DiseaseAlzheimer Disease, Early Onset

IGF2R PSEN1 INPP5D

5.68e-0499483C0750901
DiseasePresenile dementia

IGF2R PSEN1 INPP5D

5.68e-0499483C0011265
DiseaseAlzheimer Disease, Late Onset

IGF2R PSEN1 INPP5D

5.68e-0499483C0494463
DiseaseFamilial Alzheimer Disease (FAD)

IGF2R PSEN1 INPP5D

5.85e-04100483C0276496
DiseaseAlzheimer's Disease

IGF2R PSEN1 INPP5D

6.02e-04101483C0002395
DiseaseImmunologic Deficiency Syndromes

BLM CHD7

6.41e-0423482C0021051
DiseaseKallmann Syndrome

ARNT2 CHD7

8.21e-0426482C0162809
Diseaseoral squamous cell carcinoma (is_implicated_in)

CLPTM1L FAT1

9.53e-0428482DOID:0050866 (is_implicated_in)
Diseaseheart conduction disease (implicated_via_orthology)

CAMK2B CAMK2G

1.25e-0332482DOID:10273 (implicated_via_orthology)
DiseaseAutoinflammatory disorder

SH3BP2 TNFAIP3

1.49e-0335482C3860213

Protein segments in the cluster

PeptideGeneStartEntry
VYIIKGYWPLGAVVC

CHRM4

91

P08173
CLAYHYPIGWAVLRR

CCL25

31

O15444
VVRGCWILYEKPHFR

CRYBG3

2331

Q68DQ2
HYLLVEPQPWKCYRA

BCDIN3D

191

Q7Z5W3
WPLRFVIIHKRCVYY

SH3BP2

46

P78314
CGHLYAYDWISIPLV

BEST1

221

O76090
VTHYLVKWCSLPYED

CHD7

901

Q9P2D1
KRPWLAECTPIYIQY

ATP2B1

401

P20020
QYAVVHCTGYIKAWP

ARNT2

276

Q9HBZ2
PLLKYHHCVGEKYRW

NT5C

101

Q8TCD5
VYITHPAWEVRYKIV

FAT1

61

Q14517
PGVYTKVCHYLEWIR

KLK15

236

Q9H2R5
LYEPVSPHWFYCKII

DDHD2

36

O94830
INYLHLGEPKTWYVV

KDM4D

201

Q6B0I6
TCIYTLYWLFHRPLK

LRRC8E

326

Q6NSJ5
YYVLEEAWCVVRTKP

DPY19L2

696

Q6NUT2
LFPIWYRCHRPKYTS

MAS1L

176

P35410
REIEGGIIKCYHYWP

PTPN20

256

Q4JDL3
WIRKHHPYDSGIIYC

BLM

881

P54132
APCDWYYHVPVKRSE

C7orf57

16

Q8NEG2
SYVVVFLVCWLPYHV

ACKR3

256

P25106
EVLKWAHCLTVYFIP

GPR142

311

Q7Z601
LWICLAHYLPIGIYD

HSD17B2

346

P37059
YGKPVDIWACGVILY

CAMK2G

191

Q13555
FHVWIGIPFCIIYIV

OR52H1

31

Q8NGJ2
YIPGICVARVYHGWL

SLA

71

Q13239
GEHVTWRKYYINVCR

IGF2R

801

P11717
YGKPVDIWACGVILY

CAMK2B

191

Q13554
YRCYKVIHAWLIISS

PSEN1

156

P49768
CIHTWPCTYYLEPKR

SNAP47

51

Q5SQN1
KALIYTFLPHWLTCY

TAF1C

281

Q15572
LWKSYPLVHVVCQSY

INPP5D

676

Q92835
KDNIRHGVCWIYYPD

SETD7

111

Q8WTS6
LVVFLGIEPYCVKHW

SHPRH

861

Q149N8
PKYTGIWHCVRDTYH

SLC25A47

31

Q6Q0C1
AYHYVQCPVPVLKWL

SLF2

796

Q8IX21
CWPHLIRKLYCYLKE

PRAMEF2

216

O60811
VHTCWVMYGIVYTRP

CLPTM1L

21

Q96KA5
LPLRVVYYVHKGIWL

CYSLTR1

76

Q9Y271
GLLYHWKTCSPVTRY

PIGV

456

Q9NUD9
WIITAAHCVYDLYLP

TMPRSS3

251

P57727
AHCVYDLYLPKSWTI

TMPRSS3

256

P57727
VVIWYEDHKHRCPYE

ZNF653

126

Q96CK0
VYYWHKLEGRDIVPV

VSIG1

171

Q86XK7
LHWPAQECYRYPIVL

TNFAIP3

236

P21580
IWIYRQTIHCEPCYS

SCEL

666

O95171
TLTYPPELWYRKICG

SMOX

396

Q9NWM0
KYLVQVRCKPDHGYW

PRLR

201

P16471
IIHTGWKPYECYECG

ZNF33A

516

Q06730
YFWAIIHLLCVGAYK

TMEM241

151

Q24JQ0
ICIVFLNKWIYVYHG

SLC35E3

26

Q7Z769
ARGHWYPYNERLICI

ZBTB34

361

Q8NCN2