Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyCellularComponentIgG immunoglobulin complex

IGLC1 IGLC7 IGLL5

2.51e-0614413GO:0071735
GeneOntologyCellularComponentIgD immunoglobulin complex

IGLC1 IGLC7

5.60e-056412GO:0071738
GeneOntologyCellularComponentIgE immunoglobulin complex

IGLC1 IGLC7

5.60e-056412GO:0071742
GeneOntologyCellularComponentIgA immunoglobulin complex

IGLC1 IGLC7

3.88e-0415412GO:0071745
GeneOntologyCellularComponentIgM immunoglobulin complex

IGLC1 IGLC7

3.88e-0415412GO:0071753
GeneOntologyCellularComponentcytoplasmic region

SPATA7 ZC3H14 UNC13C CCDC39 BRWD1

6.63e-04360415GO:0099568
DomainAT_hook

FAM171B AHDC1

1.44e-0327392SM00384
DomainAT_hook_DNA-bd_motif

FAM171B AHDC1

1.44e-0327392IPR017956
DomainC1_1

PRKCH UNC13C

6.31e-0357392PF00130
DomainZF_DAG_PE_1

PRKCH UNC13C

7.89e-0364392PS00479
DomainZF_DAG_PE_2

PRKCH UNC13C

7.89e-0364392PS50081
DomainC1

PRKCH UNC13C

8.13e-0365392SM00109
DomainPE/DAG-bd

PRKCH UNC13C

8.38e-0366392IPR002219
DomainLIM

LDB3 LIMCH1

9.13e-0369392PF00412
Domain-

LDB3 LIMCH1

9.38e-03703922.10.110.10
DomainLIM_DOMAIN_2

LDB3 LIMCH1

9.64e-0371392PS50023
DomainZnf_LIM

LDB3 LIMCH1

9.64e-0371392IPR001781
DomainLIM_DOMAIN_1

LDB3 LIMCH1

9.64e-0371392PS00478
DomainLIM

LDB3 LIMCH1

9.64e-0371392SM00132
Pubmed

TWIST1 and chromatin regulatory proteins interact to guide neural crest cell differentiation.

DDX24 AHDC1 ZFP62 ZFPM2

9.32e-0610942433554859
Pubmed

Hnf1b haploinsufficiency differentially affects developmental target genes in a new renal cysts and diabetes mouse model.

PKHD1 LRP2 INVS

1.14e-053642333737325
Pubmed

The arrestin domain-containing 3 protein regulates body mass and energy expenditure.

ADRB2 ARRDC1

1.42e-05542221982743
Pubmed

The cytoplasmic tail of fibrocystin contains a ciliary targeting sequence.

PKHD1 LRP2

1.42e-05542220048263
Pubmed

Arf4 is required for Mammalian development but dispensable for ciliary assembly.

PKHD1 LRP2

2.98e-05742224586199
Pubmed

Structure and expression of the human immunoglobulin lambda genes.

IGLC1 IGLC7

5.10e-0594222115572
Pubmed

Gene discovery by microarray: identification of novel genes induced during growth factor-mediated muscle cell survival and differentiation.

CKAP2L LDB3 BRWD1

6.18e-056342315475267
Pubmed

Mammalian α arrestins link activated seven transmembrane receptors to Nedd4 family e3 ubiquitin ligases and interact with β arrestins.

ADRB2 ARRDC1

1.48e-041542223236378
Pubmed

Structure and function of immunoglobulins.

IGLC1 IGLC7

1.48e-041542220176268
Pubmed

Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes.

IFIH1 NAA25

1.91e-041742217554260
Pubmed

Genome-wide SNP and CNV analysis identifies common and low-frequency variants associated with severe early-onset obesity.

PRKCH FARS2

2.40e-041942223563609
Pubmed

Loss of Zeb2 in mesenchyme-derived nephrons causes primary glomerulocystic disease.

PKHD1 LRP2

2.95e-042142227591083
Pubmed

Evidence for genes on chromosome 2 contributing to alcohol dependence with conduct disorder and suicide attempts.

LRP2 CKAP2L

3.54e-042342220468071
Pubmed

Interaction proteomics analysis of polycomb proteins defines distinct PRC1 complexes in mammalian cells.

NBN TOPAZ1 AHDC1

3.77e-0411642321282530
Pubmed

Hand2 is an essential regulator for two Notch-dependent functions within the embryonic endocardium.

LYVE1 ZFPM2

3.86e-042442225497097
Pubmed

Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.

ZC3H14 HAX1 PSIP1 DDX24 TOR1AIP1 AHDC1

5.09e-0484742635850772
Pubmed

Genetic susceptibility to type 2 diabetes is associated with reduced prostate cancer risk.

IFIH1 NAA25

7.34e-043342220203524
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

NBN ZC3H14 PSIP1 DDX24 TOR1AIP1 AHDC1 HMGXB4

8.37e-04129442730804502
Pubmed

Multiple myeloma-associated chromosomal translocation activates orphan snoRNA ACA11 to suppress oxidative stress.

PSIP1 DDX24 TOR1AIP1

9.44e-0415942322751105
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

NBN ZC3H14 PSIP1 DDX24 TOR1AIP1 HMGXB4

9.47e-0495442636373674
Pubmed

Interactome analysis reveals that lncRNA HULC promotes aerobic glycolysis through LDHA and PKM2.

IFIH1 DDX24 TOR1AIP1

9.79e-0416142332572027
Cytoband14q31.3

SPATA7 ZC3H14

6.33e-051342214q31.3
CytobandEnsembl 112 genes in cytogenetic band chr22q11

IGLC1 IGLC7 P2RX6 IGLL5

5.82e-04419424chr22q11
CytobandEnsembl 112 genes in cytogenetic band chr14q31

SPATA7 ZC3H14

1.35e-0359422chr14q31
GeneFamilyLIM domain containing

LDB3 LIMCH1

3.75e-03592821218
GeneFamilyWD repeat domain containing

WDR17 NBEAL1 BRWD1

7.54e-03262283362
GeneFamilyImmunoglobulin lambda locus at 22q11.2

IGLC1 IGLC7

8.33e-0389282353
GeneFamilyPDZ domain containing

LDB3 PATJ

2.30e-021522821220
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZNF624 ZNF683 ZFP62 ZFPM2

2.37e-0271828428
ToppCellTCGA-Liver-Primary_Tumor-Hepatocellular_Carcinoma-Hepatocellular_Carcinoma-6|TCGA-Liver / Sample_Type by Project: Shred V9

PRKCH LDB3 WDR17 ZFPM2

1.92e-05169424e992530776cab922d0360b275fb9cb8bd0017b06
ToppCellHealthy-Plasmablast|Healthy / disease group, cell group and cell class

CKAP2L UNC13C IGLC7 IGLL5

2.31e-051774244ff75c609ac9edf7a94bda42eb7124c559e8b6aa
ToppCellControl-Epithelial_alveolar-AT_1-Differentiating_AT1|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PKHD1 LIMCH1 PATJ WNK3

2.31e-051774249af14a056eb6d88c6f11b09f6d4c0d3448d647d5
ToppCellLV|World / Chamber and Cluster_Paper

NCEH1 LDB3 LIMCH1 PATJ

2.46e-051804245ac6f485a58bb29462fec02dfbe8eb70864eafe3
ToppCellRV|World / Chamber and Cluster_Paper

NCEH1 LDB3 LIMCH1 PATJ

2.52e-05181424bbe1e6e59d8889bd37d6e8303116cbdcafca7236
ToppCellPND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1-AT1_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PKHD1 NCEH1 LIMCH1 PATJ

2.57e-05182424573771130247e869e4e58f22d4a1cb31989635cf
ToppCellPND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PKHD1 NCEH1 LIMCH1 PATJ

2.57e-051824246cfaa2b3b3974c13b01c943f4adb70768dcc35e4
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PKHD1 LRP2 UNC13C LDB3

2.68e-051844242cbed6462fea2622871bb7e49b0df3d984239281
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PRKCH PATJ PSIP1 BRWD1

2.68e-05184424bd786db4dc4edae6d5cfc0b69901983dea19f729
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PKHD1 LRP2 UNC13C LDB3

2.68e-05184424ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PKHD1 LRP2 UNC13C LDB3

2.68e-051844242b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellLV-15._Ventricular_Cardiomyocyte_III|World / Chamber and Cluster_Paper

NCEH1 LDB3 LIMCH1 PATJ

2.74e-051854246baccb26f999145e51b91d94315bf8d4655bef31
ToppCellControl-Endothelial-Endothelial-Vein|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PRKCH UNC13C LIMCH1 ZFPM2

2.80e-0518642492092f11ecce22c14f244e42c499af0822977e6f
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PKHD1 UNC13C LIMCH1 PATJ

2.86e-05187424f124d2c699b717b7c02a1a70493f515b83dc2f4c
ToppCellLV-04._Ventricular_Cardiomyocyte_I|World / Chamber and Cluster_Paper

NCEH1 LDB3 LIMCH1 PATJ

2.92e-051884240758b474457efa36488e0195f7357100f4b6a090
ToppCellRV-06._Ventricular_Cardiomyocyte_II|World / Chamber and Cluster_Paper

NCEH1 LDB3 LIMCH1 PATJ

2.98e-051894245e80c47f63980904c4c1ff02c201b67b456a0974
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PKHD1 UNC13C LIMCH1 PATJ

2.98e-05189424e32172ad09e93f6ac6ea2b92145b2b73003f7970
ToppCellLV-06._Ventricular_Cardiomyocyte_II|World / Chamber and Cluster_Paper

NCEH1 LDB3 LIMCH1 PATJ

3.04e-05190424de5ef606a002f85c2e0e3a36c1f259d0b85a76ff
ToppCellLV-06._Ventricular_Cardiomyocyte_II|LV / Chamber and Cluster_Paper

LDB3 LIMCH1 PATJ ZFPM2

3.10e-0519142425f3eb34f4e70761e81e84c8a5829f216108cbc6
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PRKCH PATJ PSIP1 DDX24

3.10e-05191424d9a6f61fcda4f5352488f7f55cb9b57aeacc717f
ToppCellEpithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|World / Lineage, Cell type, age group and donor

PKHD1 LIMCH1 PATJ NBEAL1

3.10e-05191424d3733c8c4bda70c4390e5601fdda6188a64be944
ToppCellLV-04._Ventricular_Cardiomyocyte_I|LV / Chamber and Cluster_Paper

NCEH1 LDB3 LIMCH1 PATJ

3.17e-05192424ad19e2c1d36a0566c9b12ced10db78f4781c8ea6
ToppCellHealthy_donor-CD8+_Tem|Healthy_donor / disease group, cell group and cell class (v2)

ZNF683 PRKCH ADRB2 DDX24

3.30e-05194424bf2e889de60b2b452a41f4d59a0f2a1865f07184
ToppCellHealthy/Control-CD8+_Tem|Healthy/Control / Disease group and Cell class

ZNF683 PRKCH ADRB2 DDX24

3.37e-05195424f4955c176c4918052dc151c5e5249223ec428272
ToppCellHealthy_donor-CD8+_Tem|World / disease group, cell group and cell class (v2)

ZNF683 PRKCH ADRB2 DDX24

3.43e-05196424b04684d319d0c462862677d0f956a389bffef535
ToppCellsevere_COVID-19-CD4+_CTL|severe_COVID-19 / disease group, cell group and cell class (v2)

ZNF683 PRKCH ADRB2 DDX24

3.50e-05197424e51b7cd03b1450dc8601b4be0453b104d6a5f955
ToppCellsevere_influenza-CD8+_Tem|severe_influenza / disease group, cell group and cell class (v2)

ZNF683 PRKCH PSIP1 DDX24

3.57e-0519842419d9516a04b75e2c8b6b66b5af25b319b0641ac9
ToppCellControl_saline-Epithelial_alveolar-AT_1-Differentiating_AT1|Control_saline / Treatment groups by lineage, cell group, cell type

PKHD1 LIMCH1 NBEAL1 WNK3

3.57e-0519842485f424cd9bb3117c9e322031024aabb87696ce47
ToppCellSepsis-Int-URO-Lymphocyte-T/NK-CD4+_CTL|Int-URO / Disease, condition lineage and cell class

ZC3H14 ZNF683 FAM171B PSIP1

3.57e-05198424717735d755745439f97ba1b71785c73945dfa9c5
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

PKHD1 LIMCH1 PATJ NBEAL1

3.64e-05199424d43c605a4ff221cf78d91678c15d2ad20f831c7f
ToppCellLPS_IL1RA_TNF-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

WDR17 CCDC39 WNK3 HMGXB4

3.64e-05199424121de4e02585de3a3010398387c523bacf8ce546
ToppCellsevere-gd_T|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

ZNF683 PRKCH ADRB2 DDX24

3.64e-05199424e5a17a9f8f3be05d6abe1116607d17633df3c7ef
ToppCellmild-CD8+_Tem|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

ZNF683 PRKCH ADRB2 DDX24

3.72e-05200424d8aec4904c9420b8f9d7508658ba1e36c66cdfcc
ToppCellsevere-CD8+_Tem|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

ZNF683 PRKCH ADRB2 DDX24

3.72e-05200424aaa2cd326dc15dee2fd975ca133359c5826f6a75
ToppCellThalamus|World / BrainAtlas - Mouse McCarroll V32

PRKCH UNC13C PATJ

1.78e-041164235ddfb2dd5459ff6d7ae38163a38eae64fda283b7
ToppCellCOVID-19-kidney-Epithelial_Doublet|COVID-19 / Disease (COVID-19 only), tissue and cell type

PKHD1 UNC13C TOPAZ1

2.49e-041304231ff28e9d3dc9a791e07d815f8fbb48f75d3f275b
ToppCell390C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1.5|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

ZNF683 ADRB2 CCDC39

4.02e-04153423764fb5e5fa028c137b8ea65dcd5e4ec9b22191e9
ToppCellT_cells-GNLY+GZMB+_T_cells|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

ZNF683 PRKCH ADRB2

4.33e-04157423e9eb56a1dd96bd2e9725a20f2cf70ddeab811bd6
ToppCell367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0|367C / Donor, Lineage, Cell class and subclass (all cells)

ZNF683 ADRB2 IGLC7

4.41e-04158423c08b5e12cc2975e52965e22ec987d0d45a9a68e9
ToppCellFLU-Healthy-1|Healthy / Virus stimulation, Condition and Cluster

IFIH1 ZNF683 ADRB2

4.49e-0415942397c8e16a7ac10ebba96daee97f9fb1d4a404f23b
ToppCellFLU-Healthy-1|FLU / Virus stimulation, Condition and Cluster

IFIH1 ZNF683 ADRB2

4.49e-04159423fe2a9f79b058e89214256e736f6e266830cdfa28
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PKHD1 LRP2 WDR17

4.58e-04160423c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PKHD1 LRP2 WDR17

4.58e-0416042325c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell367C-Lymphocytic-NK_cells-NK_cell_B1|367C / Donor, Lineage, Cell class and subclass (all cells)

ZNF624 ZNF683 ZFP62

4.66e-04161423f470b662566131dfe69a2fd01186ac8491196396
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PATJ PSIP1 BRWD1

4.66e-041614235fba13f0aa5002f7eefe219e2c6a07e163f1a50d
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c06-NR4A2|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PRKCH PATJ TOR1AIP1

4.75e-0416242380317c4253bf8e897782e562f29835f181c65b98
ToppCellChildren_(3_yrs)-Mesenchymal-vascular_smooth_muscle_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

LYVE1 LDB3 CCDC39

4.83e-041634238f24cef152f5965727bbeee116bd26c75cbba82a
ToppCellControl|World / group, cell type (main and fine annotations)

LRP2 LIMCH1 PATJ

5.27e-04168423a3511faf2cd2c2b9c8363c8b99da3f3609c43ed6
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

ZNF683 PRKCH ADRB2

5.27e-04168423b94b1f37c92e019d01ecfa3b7cc6797b6e4a56ff
ToppCellPND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CKAP2L FARS2 WNK3

5.27e-04168423a7eb28e15b591997f1aee09501cb20ae18beca08
ToppCell10x_3'_v2v3-Neoplastic-Stem-like-OPC-like-OPC-like_Prolif-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CKAP2L IGLL5 WNK3

5.37e-041694232833a8a7094e4d407eb923f2bc59b9b112c6bae4
ToppCellfacs-Diaphragm-Limb_Muscle-24m|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PKHD1 LRP2 UNC13C

5.37e-0416942312bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCell10x_3'_v2v3-Non-neoplastic-Lymphoid-NK-NK-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ZNF683 PRKCH NBEAL1

5.46e-04170423aaf29c2d4de172d366cbfc863bc741941667dde1
ToppCellPBMC-Control-Lymphocyte-B-Plasmablast-Plasmablast-Developping_Plasmablast|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CKAP2L IGLC7 IGLL5

5.55e-0417142313126a3fbee181412c13ffb0c347277b9d8f16f7
ToppCellnormal_Pleural_Fluid-T/NK_cells-Cytotoxic_CD8+_T|normal_Pleural_Fluid / Location, Cell class and cell subclass

ZNF683 PRKCH ADRB2

5.55e-041714236be81c20f4e962b414afcedfe478dd59c510d1e1
ToppCellE12.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

LYVE1 PRKCH FAM171B

5.65e-041724233b9be685fcd1634498a603b692f5ac6ddd0de176
ToppCellE12.5-Endothelial-proliferative_endothelial_cell-proliferative_endothelial_cell|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

LYVE1 PRKCH LIMCH1

5.65e-04172423ba99688e9f46671deccf824b1e77c6db0742d7df
ToppCellE12.5-Endothelial-proliferative_endothelial_cell|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

LYVE1 PRKCH LIMCH1

5.65e-041724232136170f6e1204734cec7dbf7b32e7d5179b92b5
ToppCell15-Trachea-Immune-Hematopoietic,_Natural_Killer_Cell|Trachea / Age, Tissue, Lineage and Cell class

ZNF683 PRKCH ADRB2

5.74e-041734236884af1492e8a3bb92a33303d4d5ec3343e88b00
ToppCell5'-Adult-Appendix-Hematopoietic-Myeloid-Mast_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADRB2 P2RX6 WNK3

5.74e-04173423a7dee23b1d43d3070d502487af319ff81a9a747b
ToppCellnormal_Pleural_Fluid-T/NK_cells-Cytotoxic_CD8+_T|T/NK_cells / Location, Cell class and cell subclass

ZNF683 PRKCH ADRB2

5.74e-041734231e8a43ff32eab95857c794e0bf4f0b0dba155b4a
ToppCell10x3'2.3-week_17-19-Lymphocytic_T-T_NK-CD8_T_cell|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

ZNF683 PRKCH NBEAL1

5.84e-04174423fee2ee3e888ce71f9f3f05d7dc8aaa9549480205
ToppCellsevere_influenza-Plasmablast|World / disease group, cell group and cell class (v2)

CKAP2L UNC13C CCDC39

5.94e-04175423e6d6c44510d5dc4eb0bae820125e42366f7a4e74
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

LDB3 LIMCH1 NBEAL1

5.94e-04175423316f2ea930437bf1243b1c0f45e6bd864112c6f2
ToppCell10x5'-blood-Lymphocytic_B_plasma-Plasmablasts|blood / Manually curated celltypes from each tissue

CKAP2L IGLC1 ZFP62

5.94e-041754232e048bf7961c3d86b6e12a1ebae3b3f2359af457
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

LDB3 LIMCH1 NBEAL1

5.94e-04175423a9f08e1e4c2997dcdd3e5d92daac480da19100b8
ToppCellInfluenza_Severe-Plasmablast|World / Disease group and Cell class

CKAP2L UNC13C CCDC39

5.94e-0417542314df8fc6f6beae1be7b7bd5837546d1ac1239a6f
ToppCellControl-Lymphocyte-T_NK-CD8_TCM|Control / Disease, Lineage and Cell Type

ZNF683 PSIP1 NBEAL1

6.04e-041764231a7948eb86ee1da607db4d0576312b2859d94523
ToppCellCOVID-19-kidney-Distal_Epi_Doublet_(PCT)|kidney / Disease (COVID-19 only), tissue and cell type

PKHD1 LRP2 PATJ

6.04e-0417642336f77d878a53b30465b0dea8333a3865dba75613
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L3-5_THEMIS_ELOF1|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

IFIH1 CCDC39 ZFPM2

6.04e-0417642378306517b1e52411a2ba72f141efea4d12c09f25
ToppCell10x3'2.3-week_12-13-Lymphocytic_T-T_NK-NK_T_cell|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

ZNF683 PRKCH AHDC1

6.14e-04177423e1ba7e17af2c54d3c78cdf85882168c5b896e453
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L3_LINC00507_CTXN3|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

IFIH1 CCDC39 ZFPM2

6.14e-0417742396d639407f79669f3990138793d157b94273581c
ToppCellControl-Epithelial_alveolar-AT_1|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PKHD1 LIMCH1 PATJ

6.24e-04178423aa7d43c655df493f1330a5001efaa484e4a19f69
ToppCell390C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1.5|390C / Donor, Lineage, Cell class and subclass (all cells)

ZNF683 PRKCH ADRB2

6.24e-04178423375c9449be570b4aed83611f9c6fe1665e677818
ToppCellnormal-na-Lymphocytic_B-plasmablast-female|normal / PBMC cell types (v2) per disease, treatment status, and sex

UNC13C IGLL5 CCDC39

6.24e-0417842340a280c1e35963dd45d1809a3e85b568344dd1f5
ToppCellnormal-na-Lymphocytic_B-plasmablast|normal / PBMC cell types (v2) per disease, treatment status, and sex

UNC13C IGLL5 CCDC39

6.24e-041784234fe87c713770173336177e3488f7b4a3be54f71b
ToppCellCOVID-19-kidney-Epi_(Mes)|COVID-19 / Disease (COVID-19 only), tissue and cell type

PKHD1 LRP2 PATJ

6.24e-04178423544379f5a6145429762258d426b876bb36c112f5
ToppCellnormal-na-Lymphocytic_T-CD4-positive,_alpha-beta_T_cell-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

LYVE1 PSIP1 NBEAL1

6.24e-04178423fa3585383a1e7da460c88a802aaa81246d681b6b
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_B-B_atypical-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

ZNF624 ZC3H14 AHDC1

6.34e-041794235be883d7d0be3180bb9844e4a757f0dd247294e4
ToppCellMultiple_Sclerosis-Lymphocyte-T_NK-gdT|Multiple_Sclerosis / Disease, Lineage and Cell Type

ZNF683 PRKCH ADRB2

6.34e-04179423ab8d8104b38603ec7fbc5b35d7149e71ad57c43a
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PKHD1 LIMCH1 PATJ

6.34e-0417942304ce3673e46606f63d9c87bcba3a64c96817d812
ToppCellBLOOD--(5)_Plasma| / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

IGLC7 IGLL5 CCDC39

6.45e-041804231ac0a0a715f4a36df0762bb0de44802d6ffa284c
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c07-TYROBP|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ZNF683 ADRB2 FARS2

6.45e-04180423557453b74d4a9cc95ed1c7b9a9a58e45eb02ed6a
ToppCellBLOOD--(5)_Plasmablasts| / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

IGLC7 IGLL5 CCDC39

6.45e-041804234b9be1b19d4ecd0a3b924e4557a1ecfbcff2d705
ToppCellCOVID-19-kidney-PCT-S2|COVID-19 / Disease (COVID-19 only), tissue and cell type

PKHD1 LRP2 PATJ

6.45e-04180423358923e4228035a3e90e2957392089219e90dcd7
ToppCellCOVID-19-kidney-tDL|COVID-19 / Disease (COVID-19 only), tissue and cell type

PKHD1 LRP2 PATJ

6.45e-04180423864c895b5eaedefae86f5829fa344f7b686fb59f
ToppCellFetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CKAP2L LDB3 ZFPM2

6.55e-0418142325915e2500430a902db37d79a749ce2990b69810
ToppCellMS|World / Condition, Cell_class and T cell subcluster

LYVE1 IGLC7 IGLL5

6.55e-0418142399f054a586a95947528dc3fd8043c1bda5e74cc4
ToppCellnormal_Lymph_Node-B_lymphocytes-Plasma_cells|normal_Lymph_Node / Location, Cell class and cell subclass

IGLC7 IGLL5 CCDC39

6.55e-04181423949ac3b60e7fb5968da4c4e872965fb4e10f4a35
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PKHD1 LIMCH1 PATJ

6.55e-04181423b45b11428d13950369347e051d4d517efb2bd4fd
ToppCellT_cells-Resident_memory_CD8+_T_cells|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis

ZNF683 PATJ NBEAL1

6.66e-04182423111d434b89902ec11fb07f41b8ee1a98f3991b61
ToppCellCOVID-19-kidney-Distal_Epi_Doublet_(PCT)|COVID-19 / Disease (COVID-19 only), tissue and cell type

PKHD1 LRP2 PATJ

6.66e-041824239d67717a6e13bcb54c1297a3e4e3abf4e51628a3
ToppCell3'-GW_trimst-1.5-SmallIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CKAP2L LYVE1 NCEH1

6.76e-0418342352af3c943116073c8ddd207b664342960b88929b
ToppCellCOVID-19-kidney-PCT-S1|COVID-19 / Disease (COVID-19 only), tissue and cell type

PKHD1 LRP2 PATJ

6.76e-041834236878d14026c3df6aa12e45dfad94b32fa9d9b0b7
ToppCellCOPD-Epithelial-ATII|World / Disease state, Lineage and Cell class

LRP2 LIMCH1 PATJ

6.76e-041834238e9aab4eeec2e282c2cab9bfca6dbf40d660c7b9
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-Proliferating_Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CKAP2L NCEH1 TOPAZ1

6.76e-0418342342dc31d587fbb9724b2f0be5ee8ed77233f67b86
ToppCellLPS_only-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PKHD1 LIMCH1 PATJ

6.87e-0418442342ce855b4f8475a8298192feec785bdc69bc5bb0
ToppCellCOVID-19-Epithelial_cells-AT2|COVID-19 / group, cell type (main and fine annotations)

LRP2 LIMCH1 PATJ

6.87e-04184423369b82f793deab672204558ae4e112cfa5aa9ccc
ToppCell343B-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

CKAP2L LDB3 ZFPM2

6.87e-041844236b2449ac65a2322aa0479fba0d89828f243aabbe
ToppCell343B-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

CKAP2L LDB3 ZFPM2

6.87e-04184423e90622b82fa7f16a1faaf7a4724c958f2d83341d
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

IGLC1 IGLC7 IGLL5

2.69e-0449283GAVISH_3CA_MALIGNANT_METAPROGRAM_36_IG
DiseaseCiliopathies

PKHD1 SPATA7 CCDC39 INVS

1.51e-05110404C4277690
Diseasedisease of metabolism (is_implicated_in)

NBN ADRB2

2.68e-056402DOID:0014667 (is_implicated_in)
Diseasetetralogy of Fallot (implicated_via_orthology)

ZFPM2 INVS

1.61e-0414402DOID:6419 (implicated_via_orthology)
Diseasematrix metalloproteinase 1 measurement

CKAP2L ZFPM2

1.86e-0415402EFO_0010588
DiseaseProteinuria

LRP2 UNC13C

1.86e-0415402HP_0000093
DiseaseDrug habituation

PRKCH LIMCH1 PATJ

5.13e-04115403C0013170
DiseaseSubstance-Related Disorders

PRKCH LIMCH1 PATJ

5.13e-04115403C0236969
DiseaseDrug abuse

PRKCH LIMCH1 PATJ

5.13e-04115403C0013146
DiseaseDrug Use Disorders

PRKCH LIMCH1 PATJ

5.13e-04115403C0013222
DiseaseDrug Dependence

PRKCH LIMCH1 PATJ

5.13e-04115403C1510472
DiseaseSubstance Dependence

PRKCH LIMCH1 PATJ

5.13e-04115403C0038580
DiseaseSubstance Use Disorders

PRKCH LIMCH1 PATJ

5.13e-04115403C0038586
DiseaseOrganic Mental Disorders, Substance-Induced

PRKCH LIMCH1 PATJ

5.13e-04115403C0029231
DiseasePrescription Drug Abuse

PRKCH LIMCH1 PATJ

5.13e-04115403C4316881
DiseaseSubstance abuse problem

PRKCH LIMCH1 PATJ

5.26e-04116403C0740858
Diseasestroke

NAA25 NBEAL1 C4orf54

9.85e-04144403EFO_0000712
Diseasemyocardial infarction

NAA25 NBEAL1 AHDC1 ZFPM2

1.27e-03350404EFO_0000612

Protein segments in the cluster

PeptideGeneStartEntry
TSPFKYQSLLTKNKA

ADRB2

136

P07550
SNYTPQKVKQQTAVS

AHDC1

1146

Q5TGY3
QPNVASATKKFSYKL

ARRDC1

146

Q8N5I2
NNNYKQSFKKVTPSS

CCDC39

706

Q9UFE4
YFTFIKDQTVTNPKT

NBEAL1

2371

Q6ZS30
QPQPKSYFKSISVTK

HAX1

201

O00165
RYVKAFPFTNKNQQK

LYVE1

261

Q9Y5Y7
SASPVYQAVIKSQNK

LDB3

241

O75112
PSKKKKFQTNYASTT

KIAA1109

3836

Q2LD37
KTSTPFNKSNKAASQ

KIAA1109

4381

Q2LD37
IQPTTNKQSFSYTKI

ZFPM2

456

Q8WW38
NKQSFSYTKIKSEPS

ZFPM2

461

Q8WW38
FTKNYKPVVQTTGNA

NCEH1

296

Q6PIU2
KSKQTTNFENPIYAQ

LRP2

4586

P98164
FQYPSQQATVKKSSK

HMGXB4

211

Q9UGU5
TKPSKQSNNKYAASS

IGLC1

56

P0CG04
VETTKPSKQSNNKYA

IGLL5

161

B9A064
NFVVVFKNNSTKKQY

IFIH1

986

Q9BYX4
FSNAKAYTPNKRSKI

BRWD1

1386

Q9NSI6
FTESQKTKYPTQSGK

DDX24

801

Q9GZR7
TKPSKQSNNKYAASS

IGLC7

56

A0M8Q6
KQATKYPAAQATSTA

C4orf54

1006

D6RIA3
QLFNAKNSSYSPQKK

FAM171B

426

Q6P995
YSQPKNSQDVLKTFK

LIMCH1

541

Q9UPQ0
KNTVTFSKFNFSKSN

P2RX6

201

O15547
SKNFSYNLQSATQPK

INVS

1046

Q9Y283
DTYTKLFQVKPANQK

MEIOC

366

A2RUB1
QTNSIRNYFQPSTKK

NBN

451

O60934
RKKFSVQSPTKNHYT

WDR17

326

Q8IZU2
AVVYVFSAPQNSVKK

PKHD1

3181

P08F94
RSKPKTDSYNQTKNS

CKAP2L

206

Q8IYA6
NNPKVKFSSQQAATK

PSIP1

86

O75475
KTFSQPSYLSQHKKI

ZNF624

311

Q9P2J8
LKVKFTNSNTPNSYN

TOR1AIP1

536

Q5JTV8
TAGQTKSPKFSYTFK

UNC13C

46

Q8NB66
KQQKYPTKVSFSSQE

PATJ

1381

Q8NI35
YKNNSKSLFNTLQKP

SPATA7

111

Q9P0W8
VTPVQASSDSFYNKK

TOPAZ1

751

Q8N9V7
SYPSLQQKTNAVKKL

ZFP62

126

Q8NB50
SNINQKVKFQPLSKY

FARS2

346

O95363
VTKTTNYSTVPQKQT

ZC3H14

366

Q6PJT7
SSTDDKKFTVKYPQN

ZNF683

116

Q8IZ20
ATQNPKTSFSYEKLQ

WNK3

1386

Q9BYP7
QTSTKQKTNKPTYNE

PRKCH

56

P24723
KFSKTVQGKVQSSYL

NAA25

936

Q14CX7