Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyCellularComponentmitochondrial large ribosomal subunit

MRPL47 MRPL37 MRPS18A MRPL18 MRPL38 MRPL46

3.07e-07571006GO:0005762
GeneOntologyCellularComponentorganellar large ribosomal subunit

MRPL47 MRPL37 MRPS18A MRPL18 MRPL38 MRPL46

3.07e-07571006GO:0000315
GeneOntologyCellularComponentlarge ribosomal subunit

MRPL47 MRPL37 MRPS18A MRPL18 MRPL38 MRPL46 RPL4

1.58e-061181007GO:0015934
GeneOntologyCellularComponentmitochondrial ribosome

MRPL47 MRPL37 MRPS18A MRPL18 MRPL38 MRPL46

4.94e-06911006GO:0005761
GeneOntologyCellularComponentorganellar ribosome

MRPL47 MRPL37 MRPS18A MRPL18 MRPL38 MRPL46

4.94e-06911006GO:0000313
GeneOntologyCellularComponentribosomal subunit

MRPL47 MRPL37 MRPS18A MRPL18 MRPL38 MRPL46 RPL4

4.11e-051941007GO:0044391
GeneOntologyCellularComponentmitochondrial protein-containing complex

MRPL47 MRPL37 MRPS18A MRPL18 MRPL38 MRPL46 MTX1

2.00e-042501007GO:0098798
GeneOntologyCellularComponentribosome

MRPL47 MRPL37 MRPS18A MRPL18 MRPL38 MRPL46 RPL4

2.99e-042671007GO:0005840
GeneOntologyCellularComponentheteromeric SMAD protein complex

SMAD6 SMAD7

6.23e-0481002GO:0071144
GeneOntologyCellularComponentmain axon

TRIM46 CNTNAP1 APBB1 DLG4

8.82e-04891004GO:0044304
GeneOntologyCellularComponentSMAD protein complex

SMAD6 SMAD7

9.94e-04101002GO:0071141
DomainZO

TJP2 TJP3

7.98e-053972IPR005417
DomainPDZ

MYO18A MAST2 TJP2 DLG4 MAST3 TJP3

9.36e-05141976PF00595
DomainPDZ

MYO18A MAST2 TJP2 DLG4 MAST3 TJP3

1.22e-04148976SM00228
Domain-

MYO18A MAST2 TJP2 DLG4 MAST3 TJP3

1.32e-041509762.30.42.10
DomainPDZ

MYO18A MAST2 TJP2 DLG4 MAST3 TJP3

1.36e-04151976PS50106
DomainPDZ

MYO18A MAST2 TJP2 DLG4 MAST3 TJP3

1.41e-04152976IPR001478
DomainDUF1908

MAST2 MAST3

1.59e-044972PF08926
DomainMA_Ser/Thr_Kinase_dom

MAST2 MAST3

1.59e-044972IPR015022
DomainMAST_pre-PK_dom

MAST2 MAST3

1.59e-044972IPR023142
Domain-

MAST2 MAST3

1.59e-0449721.20.1480.20
DomainGUANYLATE_KINASE_2

TJP2 DLG4 TJP3

2.23e-0423973PS50052
DomainGUANYLATE_KINASE_1

TJP2 DLG4 TJP3

2.23e-0423973PS00856
DomainGuanylate_kin

TJP2 DLG4 TJP3

3.24e-0426973PF00625
DomainGK/Ca_channel_bsu

TJP2 DLG4 TJP3

3.24e-0426973IPR008145
DomainGuanylate_kin-like_dom

TJP2 DLG4 TJP3

3.24e-0426973IPR008144
DomainGuKc

TJP2 DLG4 TJP3

3.24e-0426973SM00072
DomainRA

RALGDS RASIP1 PLCE1

5.49e-0431973SM00314
DomainDwarfin

SMAD6 SMAD7

7.32e-048972IPR013790
DomainDWB

SMAD6 SMAD7

7.32e-048972SM00524
DomainMH2

SMAD6 SMAD7

7.32e-048972PS51076
DomainMH1

SMAD6 SMAD7

7.32e-048972PS51075
Domain-

SMAD6 SMAD7

7.32e-0489723.90.520.10
DomainMAD_homology_MH1

SMAD6 SMAD7

7.32e-048972IPR013019
DomainMH2

SMAD6 SMAD7

7.32e-048972PF03166
DomainSMAD_dom_Dwarfin-type

SMAD6 SMAD7

7.32e-048972IPR001132
DomainRA

RALGDS RASIP1 PLCE1

8.56e-0436973PF00788
DomainRA

RALGDS RASIP1 PLCE1

9.28e-0437973PS50200
DomainSH3_2

ZDHHC6 TJP2 MYO15A TJP3

1.05e-0386974IPR011511
DomainSH3_2

ZDHHC6 TJP2 MYO15A TJP3

1.05e-0386974PF07653
DomainGlutathione-S-Trfase_C-like

GSTT2B GSTT2 MTX1

1.08e-0339973IPR010987
Domain-

GSTT2B GSTT2 MTX1

1.08e-03399731.20.1050.10
DomainRA_dom

RALGDS RASIP1 PLCE1

1.17e-0340973IPR000159
DomainGalactose-bd-like

PITHD1 NTN3 CNTNAP1 HERC2

1.46e-0394974IPR008979
DomainMAD_homology1_Dwarfin-type

SMAD6 SMAD7

1.70e-0312972IPR003619
DomainDWA

SMAD6 SMAD7

1.70e-0312972SM00523
DomainMH1

SMAD6 SMAD7

1.70e-0312972PF03165
DomainSMAD_FHA_domain

RASIP1 SMAD6 SMAD7

2.50e-0352973IPR008984
DomainSMAD_dom-like

SMAD6 SMAD7

3.06e-0316972IPR017855
Domain-

SMAD6 SMAD7

3.06e-03169722.60.200.10
DomainEGF

CNTNAP1 BMP1 FAT2 VWA2

4.22e-03126974PF00008
DomainSH3

ZDHHC6 TJP2 DLG4 MYO15A TJP3

5.38e-03216975SM00326
DomainGST_N

GSTT2B GSTT2

5.76e-0322972PF02798
DomainGST_NTER

GSTT2B GSTT2

5.76e-0322972PS50404
DomainSH3_domain

ZDHHC6 TJP2 DLG4 MYO15A TJP3

5.81e-03220975IPR001452
DomainIG

ILDR2 SPEG LAG3 ADGRA2 BCAM IGSF1 SDK1

6.35e-03421977SM00409
DomainIg_sub

ILDR2 SPEG LAG3 ADGRA2 BCAM IGSF1 SDK1

6.35e-03421977IPR003599
PathwayREACTOME_MITOCHONDRIAL_TRANSLATION

MRPL47 MRPL37 MRPS18A MRPL18 MRPL38 MRPL46

4.27e-0689686MM15189
PathwayREACTOME_MITOCHONDRIAL_TRANSLATION

MRPL47 MRPL37 MRPS18A MRPL18 MRPL38 MRPL46

6.63e-0696686M27446
PathwayREACTOME_TRANSLATION

MRPL47 MRPL37 MRPS18A MRPL18 MRPL38 EIF3A MRPL46 RPL4

1.46e-05231688MM15420
PathwayREACTOME_TRANSLATION

MRPL47 MRPL37 MRPS18A MRPL18 MRPL38 EIF3A MRPL46 RPL4

8.32e-05295688M8229
Pubmed

Structures of the human mitochondrial ribosome in native states of assembly.

MRPL47 MRPL37 MRPS18A MRPL18 MRPL38 MRPL46

1.06e-0852103628892042
Pubmed

Structure of the large ribosomal subunit from human mitochondria.

MRPL47 MRPL37 MRPS18A MRPL18 MRPL38 MRPL46

1.06e-0852103625278503
Pubmed

Expression analysis of mammalian mitochondrial ribosomal protein genes.

MRPL47 MRPL37 MRPS18A MRPL18 MRPL38 MRPL46

1.36e-0779103632987154
Pubmed

Structure and Function of the Mitochondrial Ribosome.

MRPL47 MRPL37 MRPS18A MRPL18 MRPL38 MRPL46

1.70e-0782103627023846
Pubmed

Smad6 and Smad7 are co-regulated with hepcidin in mouse models of iron overload.

TFR2 SMAD6 SMAD7

5.01e-076103322960056
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

SPEG CARD10 MAST2 ADGRA2 KIAA2013 AATK MROH6 KBTBD11 BCAM HERC2 MRPL46 PRRT4 SMAD7 TJP3 HR

9.26e-0711051031535748872
Pubmed

mTORC1 activity regulates post-translational modifications of glycine decarboxylase to modulate glycine metabolism and tumorigenesis.

IRS4 MYO18A PRPF40A SRRT RBM6 TJP2 EIF3A RPL4

1.67e-06274103834244482
Pubmed

A High-Density Human Mitochondrial Proximity Interaction Network.

IRS4 MRPL47 RBM33 USP11 MRPL37 APBB1 CPD SNAP47 MRPS18A MRPL18 MAGED2 MRPL38 ALDH1B1 HERC2 MRPL46 MTX1 RPL4

1.86e-0614961031732877691
Pubmed

Network organization of the human autophagy system.

IRS4 USP11 MAGED2 XIRP2 TJP2 MRPL38 EIF3A MAST3 TEDC1

6.36e-06437103920562859
Pubmed

Inhibitory Smad proteins promote the differentiation of mouse embryonic stem cells into ependymal-like ciliated cells.

SMAD6 SMAD7

8.69e-062103220807502
Pubmed

Gene structure, expression and chromosomal localization of murine theta class glutathione transferase mGSTT1-1.

GSTT2B GSTT2

8.69e-06210329854036
Pubmed

Defective bone morphogenic protein signaling underlies hepcidin deficiency in HFE hereditary hemochromatosis.

SMAD6 SMAD7

8.69e-062103220658468
Pubmed

Identification and characterization of GSTT3, a third murine Theta class glutathione transferase.

GSTT2B GSTT2

8.69e-062103212038961
Pubmed

Inhibitory SMADs: potential regulators of ovarian function.

SMAD6 SMAD7

8.69e-062103225550343
Pubmed

Expressions of inhibitory Smads, Smad6 and Smad7, are differentially regulated by TPA in human lung fibroblast cells.

SMAD6 SMAD7

8.69e-062103215033458
Pubmed

A genome-wide association study shows that common alleles of SMAD7 influence colorectal cancer risk.

SMAD6 SMAD7

8.69e-062103217934461
Pubmed

Linkage disequilibrium between two high-frequency deletion polymorphisms: implications for association studies involving the glutathione-S transferase (GST) genes.

GSTT2B GSTT2

8.69e-062103219424424
Pubmed

Mammalian class theta GST and differential susceptibility to carcinogens: a review.

GSTT2B GSTT2

8.69e-062103211018744
Pubmed

Characterization of a cDNA and gene encoding the mouse theta class glutathione transferase mGSTT2 and its localization to chromosome 10B5-C1.

GSTT2B GSTT2

8.69e-06210328617493
Pubmed

Prognostic value of the expression of Smad6 and Smad7, as inhibitory Smads of the TGF-beta superfamily, in esophageal squamous cell carcinoma.

SMAD6 SMAD7

8.69e-062103215736400
Pubmed

Characterization of a human class-Theta glutathione S-transferase with activity towards 1-menaphthyl sulphate.

GSTT2B GSTT2

8.69e-06210321417752
Pubmed

Molecular cloning of a cDNA and chromosomal localization of a human theta-class glutathione S-transferase gene (GSTT2) to chromosome 22.

GSTT2B GSTT2

8.69e-06210327789971
Pubmed

Identification and characterization of over 100 mitochondrial ribosomal protein pseudogenes in the human genome.

MRPL47 MRPL37 MRPS18A MRPL18 MRPL38 MRPL46

1.78e-05182103612706105
Pubmed

Minor contribution of SMAD7 and KLF10 variants to genetic susceptibility of type 2 diabetes.

SMAD6 SMAD7

2.60e-053103217931948
Pubmed

The distribution of theta-class glutathione S-transferases in the liver and lung of mouse, rat and human.

GSTT2B GSTT2

2.60e-05310328761485
Pubmed

Genetic susceptibility to keloid scarring: SMAD gene SNP frequencies in Afro-Caribbeans.

SMAD6 SMAD7

2.60e-053103218445023
Pubmed

Bone morphogenetic protein and transforming growth factor beta inhibitory Smads 6 and 7 are expressed in human adult normal and osteoarthritic cartilage in vivo and are differentially regulated in vitro by interleukin-1beta.

SMAD6 SMAD7

2.60e-053103215529348
Pubmed

Hsa-miR-186-5p regulates TGFβ signaling pathway through expression suppression of SMAD6 and SMAD7 genes in colorectal cancer.

SMAD6 SMAD7

2.60e-053103233938174
Pubmed

Roles of ZO-1 and ZO-2 in establishment of the belt-like adherens and tight junctions with paracellular permselective barrier function.

TJP2 TJP3

2.60e-053103219538286
Pubmed

Different effects of ZO-1, ZO-2 and ZO-3 silencing on kidney collecting duct principal cell proliferation and adhesion.

TJP2 TJP3

2.60e-053103225486565
Pubmed

Glutathione S-transferases promote proinflammatory astrocyte-microglia communication during brain inflammation.

GSTT2B GSTT2

2.60e-053103230783009
Pubmed

A second tyrosinase-related protein, TRP-2, maps to and is mutated at the mouse slaty locus.

BMP1 HR

2.60e-05310321537334
Pubmed

Inhibitory smads and tgf-Beta signaling in glomerular cells.

SMAD6 SMAD7

2.60e-053103212397035
Pubmed

Yes-associated protein (YAP65) interacts with Smad7 and potentiates its inhibitory activity against TGF-beta/Smad signaling.

SMAD6 SMAD7

2.60e-053103212118366
Pubmed

The human mitochondrial ribosomal protein genes: mapping of 54 genes to the chromosomes and implications for human disorders.

MRPL37 MRPS18A MRPL18 MRPL38

2.72e-0558103411543634
Pubmed

The histone acetyltransferase KAT6A is recruited to unmethylated CpG islands via a DNA binding winged helix domain.

ZNF346 MRPL47 MRPL37 MRPS18A MRPL18 MRPL38 MRPL46 RPL4

3.52e-05417103836537216
Pubmed

USP15 targets ALK3/BMPR1A for deubiquitylation to enhance bone morphogenetic protein signalling.

USP11 SMAD6 SMAD7

3.73e-0522103324850914
Pubmed

SPATA2 Links CYLD to LUBAC, Activates CYLD, and Controls LUBAC Signaling.

MRPL47 MRPL37 MRPS18A MRPL18 MAGED2 EIF3A MRPL46 MVP RPL4

4.36e-05558103927591049
Pubmed

Characterization of the ubinuclein protein as a new member of the nuclear and adhesion complex components (NACos).

TJP2 TJP3

5.19e-054103218823282
Pubmed

Identification, characterization, and crystal structure of the Omega class glutathione transferases.

GSTT2B GSTT2

5.19e-054103210783391
Pubmed

Dynamic assembly of tight junction-associated proteins ZO-1, ZO-2, ZO-3 and occludin during mouse tooth development.

TJP2 TJP3

5.19e-054103212507281
Pubmed

Binding of PTEN to specific PDZ domains contributes to PTEN protein stability and phosphorylation by microtubule-associated serine/threonine kinases.

MAST2 MAST3

5.19e-054103215951562
Pubmed

Smad6 inhibits signalling by the TGF-beta superfamily.

SMAD6 SMAD7

5.19e-05410329335505
Pubmed

Inhibition of BMP2-induced, TAK1 kinase-mediated neurite outgrowth by Smad6 and Smad7.

SMAD6 SMAD7

5.19e-054103211737269
Pubmed

Downregulation of ZEB1 and overexpression of Smad7 contribute to resistance to TGF-beta1-mediated growth suppression in adult T-cell leukemia/lymphoma.

SMAD6 SMAD7

5.19e-054103220514018
Pubmed

Modulation of thrombomodulin-dependent activation of human protein C through differential expression of endothelial Smads.

SMAD6 SMAD7

5.19e-054103212407115
Pubmed

Genetic modifiers interact with Cpe(fat) to affect body weight, adiposity, and hyperglycemia.

CPD HR

5.19e-054103215870393
Pubmed

Acetylation regulates gluconeogenesis by promoting PEPCK1 degradation via recruiting the UBR5 ubiquitin ligase.

IRS4 USP11 MAGED2 RPL4

5.72e-0570103421726808
Pubmed

BioID-based Identification of Skp Cullin F-box (SCF)β-TrCP1/2 E3 Ligase Substrates.

MRPL47 MRPL37 MAST2 MRPS18A MRPL38 MAST3

5.96e-05226103625900982
Pubmed

The large subunit of the mammalian mitochondrial ribosome. Analysis of the complement of ribosomal proteins present.

MRPL47 MRPL18 MRPL46

6.24e-0526103311551941
Pubmed

Human transcription factor protein interaction networks.

IRS4 MRPL47 RBM33 USP11 MRPL37 MYO18A PRPF40A MRPS18A SRRT MAGED2 RBM6 MRPL38 EIF3A HERC2

8.28e-0514291031435140242
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

TRIM46 CACNA1A ILDR2 CNTNAP1 MYO18A SNAP47 PRPF40A SRRT KBTBD11 TJP2 DLG4 EIF3A ALDH1B1 RPL4

8.40e-0514311031437142655
Pubmed

A tightly organized, conserved gene cluster on mouse chromosome 3 (E3-F1).

TRIM46 MTX1

8.64e-05510328597643
Pubmed

ADAM22, a Kv1 channel-interacting protein, recruits membrane-associated guanylate kinases to juxtaparanodes of myelinated axons.

CNTNAP1 DLG4

8.64e-055103220089912
Pubmed

Structure and organization of the human theta-class glutathione S-transferase and D-dopachrome tautomerase gene complex.

GSTT2B GSTT2

8.64e-05510329729470
Pubmed

Developmentally regulated expression of Smad3, Smad4, Smad6, and Smad7 involved in TGF-beta signaling.

SMAD6 SMAD7

8.64e-055103211231077
Pubmed

FKBP12 functions as an adaptor of the Smad7-Smurf1 complex on activin type I receptor.

SMAD6 SMAD7

8.64e-055103216720724
Pubmed

Identification of mammalian mitochondrial ribosomal proteins (MRPs) by N-terminal sequencing of purified bovine MRPs and comparison to data bank sequences: the large subribosomal particle.

MRPL37 MRPL38

8.64e-055103210600119
Pubmed

Degradation of the tumor suppressor Smad4 by WW and HECT domain ubiquitin ligases.

SMAD6 SMAD7

8.64e-055103215817471
Pubmed

Early embryonic lethality of mice lacking ZO-2, but Not ZO-3, reveals critical and nonredundant roles for individual zonula occludens proteins in mammalian development.

TJP2 TJP3

8.64e-055103218172007
Pubmed

Protein interactions at the tight junction. Actin has multiple binding partners, and ZO-1 forms independent complexes with ZO-2 and ZO-3.

TJP2 TJP3

8.64e-055103210575001
Pubmed

Promoting bone morphogenetic protein signaling through negative regulation of inhibitory Smads.

SMAD6 SMAD7

8.64e-055103211483516
Pubmed

Proteomic identification of common SCF ubiquitin ligase FBXO6-interacting glycoproteins in three kinds of cells.

DPP7 CNTNAP1 CPD CACHD1 PLA2G15 TFR2 EIF3A ALDH1B1 RPL4

8.93e-05613103922268729
Pubmed

Smad7 Inhibits chondrocyte differentiation at multiple steps during endochondral bone formation and down-regulates p38 MAPK pathways.

SMAD6 SMAD7

1.29e-046103218644788
Pubmed

Fine-tuning BMP7 signalling in adipogenesis by UBE2O/E2-230K-mediated monoubiquitination of SMAD6.

SMAD6 SMAD7

1.29e-046103223455153
Pubmed

Vascular MADs: two novel MAD-related genes selectively inducible by flow in human vascular endothelium.

SMAD6 SMAD7

1.29e-04610329256479
Pubmed

SMAD expression in the testis: an insight into BMP regulation of spermatogenesis.

SMAD6 SMAD7

1.29e-046103218069690
Pubmed

Gene-environment interactions and obesity traits among postmenopausal African-American and Hispanic women in the Women's Health Initiative SHARe Study.

ZPLD1 CNTNAP1 BCAM

1.54e-0435103323192594
Pubmed

Defining the membrane proteome of NK cells.

MYO18A RABAC1 B3GALT6 CPD PRPF40A KIAA2013 MAGED2 EIF3A HERC2 MVP RPL4 SLC27A3

1.79e-0411681031219946888
Pubmed

Arkadia amplifies TGF-beta superfamily signalling through degradation of Smad7.

SMAD6 SMAD7

1.81e-047103214657019
Pubmed

Can't get no SMADisfaction: Smad proteins as positive and negative regulators of TGF-beta family signals.

SMAD6 SMAD7

1.81e-047103210376010
Pubmed

Regulation of transforming growth factor-beta signaling by protein inhibitor of activated STAT, PIASy through Smad3.

SMAD6 SMAD7

1.81e-047103212815042
Pubmed

STRAP and Smad7 synergize in the inhibition of transforming growth factor beta signaling.

SMAD6 SMAD7

1.81e-047103210757800
Pubmed

High-throughput analyses of hnRNP H1 dissects its multi-functional aspect.

NTN3 CARD10 MIR1915HG BMP1 METRN MAGED2 RBM6 DLG4 TUG1 SMAD6 TEDC1

2.25e-0410211031126760575
Pubmed

Quantitative study of the interactome of PKCζ involved in the EGF-induced tumor cell chemotaxis.

MRPL37 SRRT MRPL18 MRPL38 MRPL46

2.26e-04184103523402259
Pubmed

Remarkable versatility of Smad proteins in the nucleus of transforming growth factor-beta activated cells.

SMAD6 SMAD7

2.40e-048103210647776
Pubmed

The novel E3 ubiquitin ligase Tiul1 associates with TGIF to target Smad2 for degradation.

SMAD6 SMAD7

2.40e-048103215359284
Pubmed

Smurf1 interacts with transforming growth factor-beta type I receptor through Smad7 and induces receptor degradation.

SMAD6 SMAD7

2.40e-048103211278251
Pubmed

Smad7 inhibits transforming growth factor-beta family type i receptors through two distinct modes of interaction.

SMAD6 SMAD7

2.40e-048103220663871
Pubmed

TGF-beta signaling by Smad proteins.

SMAD6 SMAD7

2.40e-048103210708949
Pubmed

p32/gC1qR is indispensable for fetal development and mitochondrial translation: importance of its RNA-binding ability.

MRPL18 MRPL38 MRPL46

2.48e-0441103322904065
Pubmed

RNA-binding proteins with basic-acidic dipeptide (BAD) domains self-assemble and aggregate in Alzheimer's disease.

MRPL47 PRPF40A MRPS18A SRRT MRPL18 MAGED2 MRPL38 MRPL46 RPL4

2.75e-04713103929802200
Pubmed

Profiling the interactome of protein kinase C ζ by proteomics and bioinformatics.

MRPL37 MRPL18 MRPL38 MRPL46

2.76e-04105103429491746
Pubmed

A mitochondrial protein compendium elucidates complex I disease biology.

NDUFAF8 MRPL47 MRPL37 ABCB6 PLA2G15 MRPS18A MRPL18 MRPL38 ALDH1B1 MRPL46 MTX1

2.79e-0410471031118614015
Pubmed

Holding their own: the noncanonical roles of Smad proteins.

SMAD6 SMAD7

3.08e-049103219018011
Pubmed

TGF-beta signal transduction.

SMAD6 SMAD7

3.08e-04910329759503
Pubmed

Axin is a scaffold protein in TGF-beta signaling that promotes degradation of Smad7 by Arkadia.

SMAD6 SMAD7

3.08e-049103216601693
Pubmed

Smad7 Protein Interacts with Receptor-regulated Smads (R-Smads) to Inhibit Transforming Growth Factor-β (TGF-β)/Smad Signaling.

SMAD6 SMAD7

3.08e-049103226555259
Pubmed

The Smad pathway.

SMAD6 SMAD7

3.08e-049103210708948
Pubmed

NEDD4-2 (neural precursor cell expressed, developmentally down-regulated 4-2) negatively regulates TGF-beta (transforming growth factor-beta) signalling by inducing ubiquitin-mediated degradation of Smad2 and TGF-beta type I receptor.

SMAD6 SMAD7

3.08e-049103215496141
Pubmed

Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.

IRS4 USP11 SRRT MAGED2 RBM6 SMG9 HERC2

3.45e-04440103734244565
Pubmed

Comparative interactome analysis of α-arrestin families in human and Drosophila.

USP11 CPD PRPF40A KIAA2013 MAGED2 HERC2

3.48e-04313103638270169
Pubmed

An interspecific backcross linkage map of the proximal half of mouse chromosome 14.

BMP1 HR

3.85e-041010321971251
Pubmed

Negative regulation of transforming growth factor-beta (TGF-beta) signaling by WW domain-containing protein 1 (WWP1).

SMAD6 SMAD7

3.85e-0410103215221015
Pubmed

Smad6 inhibits BMP/Smad1 signaling by specifically competing with the Smad4 tumor suppressor.

SMAD6 SMAD7

3.85e-041010329436979
Pubmed

Tob1 controls dorsal development of zebrafish embryos by antagonizing maternal beta-catenin transcriptional activity.

SMAD6 SMAD7

3.85e-0410103216890162
Pubmed

Spatio-temporal distribution of Smads and role of Smads/TGF-β/BMP-4 in the regulation of mouse bladder organogenesis.

SMAD6 SMAD7

3.85e-0410103223620745
Pubmed

A functional peptidyl-tRNA hydrolase, ICT1, has been recruited into the human mitochondrial ribosome.

MRPL47 MRPL37 MRPS18A MRPL18 MRPL46

3.88e-04207103520186120
Pubmed

The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.

ZNF346 MYO18A B3GALT6 SRRT MAGED2 RBM6 HERC2 MRPL46 RPL4

4.33e-04759103935915203
Pubmed

Cytoplasmic Metadherin (MTDH) provides survival advantage under conditions of stress by acting as RNA-binding protein.

JADE3 ADGRA2 LOXL4 RPL4 SDK1

4.52e-04214103522199357
InteractionMRPL35 interactions

MRPL47 MRPL37 MRPS18A MRPL18 MRPL38 MRPL46 RPL4

5.27e-07941037int:MRPL35
InteractionMRPL1 interactions

MRPL47 USP11 MRPL37 C3orf20 PRPF40A MRPS18A MRPL18 MRPL38 MRPL46

1.08e-062051039int:MRPL1
InteractionMRPL30 interactions

ZNF346 MRPL47 MRPL37 MRPS18A MRPL18 MRPL38 HERC2 MRPL46

1.37e-061561038int:MRPL30
InteractionMRPL52 interactions

ZNF346 MRPL47 MRPL37 MRPS18A MRPL18 MRPL38 MRPL46 RPL4

1.59e-061591038int:MRPL52
InteractionMRPL55 interactions

MRPL47 MRPL37 MRPS18A SORT1 MRPL18 MRPL46 RPL4

6.62e-061371037int:MRPL55
InteractionMRPL18 interactions

ZNF346 MRPL47 MRPL37 MRPS18A MRPL18 MRPL38 HERC2 MRPL46

8.69e-062001038int:MRPL18
InteractionMRPL32 interactions

ZNF346 MRPL47 MRPL37 MRPS18A MRPL18 MRPL38 MRPL46

9.19e-061441037int:MRPL32
InteractionMRPS18A interactions

ZNF346 MRPL47 MRPL37 MRPS18A MRPL18 MRPL38 MRPL46

1.20e-051501037int:MRPS18A
InteractionRPL37 interactions

MRPL47 MRPL37 MRPS18A MRPL18 MRPL38 RPL4 MAST3

1.75e-051591037int:RPL37
InteractionMRPL17 interactions

ZNF346 MRPL47 MRPL37 MRPS18A MRPL18 MRPL38 MRPL46

1.82e-051601037int:MRPL17
InteractionMRPL57 interactions

MRPL47 MRPL37 MRPS18A MRPL18 MRPL38 MRPL46

1.93e-051081036int:MRPL57
InteractionMRPL13 interactions

ZNF346 MRPL47 MRPL37 MRPS18A MRPL18 MRPL38 MRPL46 RPL4

2.46e-052311038int:MRPL13
InteractionMRPL34 interactions

MRPL47 MRPL37 MRPS18A MRPL18 MRPL46

3.37e-05721035int:MRPL34
InteractionMRPL42 interactions

MRPL47 MRPL37 PRPF40A MRPS18A SRRT MRPL18 MRPL38 MRPL46

3.43e-052421038int:MRPL42
InteractionMRPL3 interactions

ZNF346 MRPL47 MRPL37 MRPS18A MRPL18 MRPL38 MRPL46

4.62e-051851037int:MRPL3
InteractionMRPL10 interactions

MRPL47 MRPL37 MRPS18A MRPL18 MRPL38 HERC2 MRPL46

5.12e-051881037int:MRPL10
InteractionMRPL51 interactions

MRPL47 MRPL37 MRPS18A MRPL18 MRPL38 MRPL46

5.99e-051321036int:MRPL51
InteractionMRPL53 interactions

MRPL47 MRPL37 MRPS18A MRPL18 MRPL38 HERC2 MRPL46

6.66e-051961037int:MRPL53
InteractionMRPL14 interactions

MRPL47 MRPL37 MRPS18A MRPL18 MRPL38 MRPL46

6.79e-051351036int:MRPL14
InteractionMRPL46 interactions

MRPL47 MRPL37 MRPS18A MRPL18 MRPL38 EIF3A MRPL46

6.88e-051971037int:MRPL46
InteractionMRPS30 interactions

MRPL47 MRPL37 MRPS18A MRPL18 MRPL38 HERC2 MRPL46

9.67e-052081037int:MRPS30
InteractionMRPL24 interactions

MRPL47 MRPL37 MRPS18A SORT1 MRPL18 MRPL38 MRPL46

1.06e-042111037int:MRPL24
InteractionMRPL15 interactions

ZNF346 MRPL47 MRPL37 MRPS18A MRPL18 MRPL38 MRPL46

1.15e-042141037int:MRPL15
InteractionKLF15 interactions

IRS4 MRPL47 MRPL37 MRPS18A C11orf68 MRPL38 EIF3A VWA2

1.22e-042901038int:KLF15
InteractionMRPL23 interactions

MRPL47 MRPL37 RIPK4 MRPS18A MRPL18 MRPL38 MRPL46

1.33e-042191037int:MRPL23
InteractionMRPL48 interactions

MRPL47 MRPL37 RIPK4 MRPL18 AP4M1 MRPL46

1.73e-041601036int:MRPL48
InteractionZNF341 interactions

PRPF40A C11orf68 ALDH1B1

1.86e-04221033int:ZNF341
InteractionNGRN interactions

ZNF346 MRPL47 MRPL37 MRPS18A MRPL18 MRPL38 MRPL46

2.06e-042351037int:NGRN
InteractionMRPL33 interactions

MRPL47 MRPL37 MRPS18A MRPL18

2.36e-04591034int:MRPL33
InteractionGLDC interactions

IRS4 MYO18A PRPF40A SRRT RBM6 TJP2 EIF3A RPL4

2.43e-043211038int:GLDC
InteractionRAB5A interactions

DPP7 IRS4 RBM33 USP11 APBB1 RABAC1 CPD CACHD1 SNAP47 EIF3A HERC2 MVP

2.58e-0470610312int:RAB5A
InteractionMRPL19 interactions

MRPL47 MRPL37 MRPS18A MRPL18 MRPL38 MRPL46

2.72e-041741036int:MRPL19
InteractionMRPL38 interactions

MRPL47 MRPL37 PRPF40A MRPS18A MRPL18 MRPL38 MRPL46

2.78e-042471037int:MRPL38
InteractionMRPL20 interactions

MRPL47 MRPL37 MRPS18A MRPL18 MRPL38 MRPL46

2.89e-041761036int:MRPL20
InteractionMALSU1 interactions

MRPL47 MRPL37 MRPS18A MRPL18 MRPL38 MRPL46

2.98e-041771036int:MALSU1
InteractionMRPL28 interactions

ZNF346 MRPL47 MRPL37 MRPS18A MRPL18 MRPL38 MRPL46

2.99e-042501037int:MRPL28
InteractionRBMS2 interactions

ZNF346 MRPL47 MRPL37 MRPS18A MRPL18 MRPL38 MRPL46

3.07e-042511037int:RBMS2
InteractionMRPL21 interactions

ZNF346 MRPL47 MRPL37 MRPS18A MRPL18 MRPL38

3.07e-041781036int:MRPL21
InteractionMRPL54 interactions

NDUFAF8 MRPL18 MRPL38 MRPL46

3.23e-04641034int:MRPL54
InteractionMRPL40 interactions

MRPL47 MRPL37 MRPS18A MRPL18 MRPL38 MRPL46

3.26e-041801036int:MRPL40
InteractionRANBP10 interactions

CACHD1 BMP1 MRPL18 MRPL38 IGSF1

3.50e-041181035int:RANBP10
Cytoband17q25.3

NDUFAF8 LINC00482 AATK MRPL38

8.25e-05101103417q25.3
Cytoband7p22.2

FBXL18 SDK1

2.22e-041010327p22.2
GeneFamilyMitochondrial ribosomal proteins

MRPL47 MRPL37 MRPS18A MRPL18 MRPL38 MRPL46

3.86e-0779656646
GeneFamilyCalcium voltage-gated channel subunits|Membrane associated guanylate kinases

CARD10 TJP2 DLG4 TJP3

2.14e-0626654904
GeneFamilyPDZ domain containing

MYO18A MAST2 TJP2 DLG4 MAST3 TJP3

1.76e-051526561220
GeneFamilySMAD family

SMAD6 SMAD7

3.51e-048652750
GeneFamilyImmunoglobulin like domain containing

LAG3 ADGRA2 BCAM IGSF1 SDK1

6.47e-04193655594
GeneFamilyGlutathione S-transferases

GSTT2B GSTT2

3.62e-0325652567
CoexpressionGSE3039_ALPHAALPHA_CD8_TCELL_VS_B1_BCELL_UP

TRIM46 LAG3 PLA2G15 KBTBD11 ALDH1B1 MVP RPL4 CTSO

1.19e-062001028M6440
CoexpressionGSE17721_0.5H_VS_8H_CPG_BMDC_UP

MRPL47 SPEG MYO18A PLA2G15 SORT1 MAST3 SLC27A3

1.36e-052001027M4126
CoexpressionAtlasdev lower uro neuro_e14.5_PelvicGanglion_Sox10_k-means-cluster#1_top-relative-expression-ranked_1000

USP11 SPEG APBB1 RABAC1 ABCB6 ADGRA2 SNAP47 CHRNB4 FAM210B C11orf68 DLG4 MTX1

3.17e-0831010212gudmap_dev lower uro neuro_e14.5_PelvicGanglion_Sox10_k1_1000
ToppCelldroplet-Liver-nan-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CPD ADGRA2 CHRNB4 RASIP1 FHDC1 BCAM SLC27A3

2.17e-071811037a53f05c4c47465ee62e353716456bd09ab464b23
ToppCellTracheal-10x5prime-Stromal-Schwann-Schwann_Myelinating|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CACNA1A ILDR2 LGI4 AATK FBXL18 IGSF1 HR

4.12e-0719910372b567b6fd8addf059bbf2b72c55a7647aefdc595
ToppCellCOVID-19-Heart-VSMC|Heart / Disease (COVID-19 only), tissue and cell type

CACNA1A SPEG SORT1 BMP1 SDK1 PLCE1

3.79e-061791036a69ad6912b5c10bb9f9d800f724c792341e9bab1
ToppCellPND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ILDR2 CNTNAP1 LGI4 BMP1 BCAM PLCE1

4.04e-061811036330d4322f4c4373f706273c1f4e218b59051b7fd
ToppCellPND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ILDR2 CNTNAP1 LGI4 BMP1 BCAM PLCE1

4.04e-0618110363f4d5d79c1286614514b0e8134079d6128a2a23e
ToppCellIPF-Epithelial-Basal|World / Disease state, Lineage and Cell class

CACHD1 RIPK4 FAT2 LOXL4 BCAM SDK1

5.66e-0619210369b91e0b162e6f3ce86dd15cc33c2e745d069581f
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW08-Neuronal-GABAergic_neurons|GW08 / Sample Type, Dataset, Time_group, and Cell type.

LAG3 PLEKHG4B METRN ABHD16B ZDHHC6 SLC27A3

6.56e-061971036e1a80c1aa7f7e83f5d19a40fe37db5c5a6c25685
ToppCellTracheal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_systemic_arterial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CACNA1A SPEG ADGRA2 SORT1 BCAM SDK1

6.75e-0619810367dd874b09c81cc512ccc1e9b65f290a5f94d736e
ToppCelldroplet-Lung-30m-Hematologic-myeloid-interstitial_macrophage-interstitial_macrophage_l12|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ILDR2 RALGDS JADE3 SPEG PLA2G15

4.09e-0516510356dda1c7fd812792bd2e4fb1a7ccb82a3552b0a3b
ToppCelldroplet-Thymus-nan-24m-Lymphocytic-nan|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBC1D30 LAG3 LGI4 CHRNB4 FHDC1

4.46e-05168103504a7810f95196a21325356b42084f96c11af5964
ToppCellfacs-Marrow-B-cells-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACHD1 CLEC2L FAM210B FHDC1 HR

4.46e-05168103517fb9426eeea407b26fb895b8397faca95b7552d
ToppCellfacs-Marrow-B-cells-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACHD1 CLEC2L FAM210B FHDC1 HR

4.46e-051681035a61b39884851384cffd430079040546d125b2b40
ToppCellControl-Epithelial_cells-Airway_basal|Control / group, cell type (main and fine annotations)

CACHD1 FAT2 FBXL18 BCAM SDK1

4.85e-0517110353965ced4be6db14265a90673502fceee425837ca
ToppCell3'-Adult-LymphNode-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CACNA1A APBB1 LGI4 LOXL4 BCAM

5.56e-05176103556e19240f4a7b617a986e3c0854b757394e78251
ToppCell3'-Adult-LymphNode-Mesenchymal-Pericytes|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CACNA1A APBB1 LGI4 LOXL4 BCAM

5.56e-051761035c88b46fe29ae7606c8880a6ff0ebb85c0dfda8bd
ToppCellnucseq-Epithelial-Epithelial_Airway-Basal/Suprabasal-Basal|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CACHD1 RIPK4 FAT2 BCAM SDK1

5.71e-051771035ce86dfaeb74d995a19aea62f0fb15c4c0bb854b0
ToppCellCOPD-Epithelial-Basal|Epithelial / Disease state, Lineage and Cell class

CACHD1 RIPK4 FAT2 LOXL4 BCAM

5.86e-051781035441d1dba720141891b11f404744c59834d80e6c5
ToppCell390C-Endothelial_cells-Endothelial-E-|390C / Donor, Lineage, Cell class and subclass (all cells)

MYO18A CARD10 RASIP1 BCAM SMAD6

5.86e-051781035804ac3725c1f88e2212172bfb9aa01d97a735621
ToppCellPND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_G2M|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ILDR2 CNTNAP1 SDK1 PLCE1 HR

5.86e-051781035c77a1d1a9aef0ab51b4408b9e84f201219788ca2
ToppCell390C-Endothelial_cells-Endothelial-E|390C / Donor, Lineage, Cell class and subclass (all cells)

MYO18A CARD10 RASIP1 BCAM SMAD6

5.86e-051781035ad6dc4a375664c919bd48c35c48a561fc5a7de8c
ToppCelldroplet-Lung-LUNG-30m-Endothelial-Artery_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACHD1 RASIP1 CLEC2L PRRT4 SMAD6

6.02e-051791035a09647750eba9d93c5efc1db3b555fefb5eec7b5
ToppCelldroplet-Spleen-nan-24m-Hematologic-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCB6 CACHD1 TFR2 FAM210B FHDC1

6.02e-051791035f3f9c7e575bc4d9d3bce649b90254182e8f6aaec
ToppCelldroplet-Spleen-nan-24m-Hematologic|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCB6 CACHD1 TFR2 FAM210B FHDC1

6.02e-05179103501e0b49e7f03ac9c3e6c34708ead300d27236b8b
ToppCellChildren_(3_yrs)-Immune-enucleated_erythrocyte-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

NDUFAF8 RASIP1 KBTBD11 MRPL46 TEDC1

6.34e-051811035c029cecbd7182c70b9893d8c86f334c16291a0db
ToppCellCOPD-Epithelial-Basal|World / Disease state, Lineage and Cell class

CACHD1 RIPK4 LOXL4 BCAM SDK1

6.34e-0518110356d8a886b4afe729f8a05b9c0f4ea9375de735da4
ToppCelldroplet-Lung-30m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CACHD1 CLEC2L FHDC1 PRRT4 SMAD6

6.68e-0518310356f8f997ffc9eaebca2683de125b6069d07c07d26
ToppCelldroplet-Liver-nan-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADGRA2 CHRNB4 RASIP1 BCAM SLC27A3

6.68e-051831035709a486154b3157427deb3b8886b63ac39ea42dd
ToppCelldroplet-Liver-nan-3m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADGRA2 CHRNB4 RASIP1 BCAM SLC27A3

6.68e-051831035dc06f19f6f80f4c7f13f1f990c1fe0f91ba64ea7
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ILDR2 SORT1 ZDHHC6 SMAD6 PLCE1

6.68e-0518310353c516fe5083f02bad1f464ed284010b4131a833c
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ILDR2 SORT1 ZDHHC6 SMAD6 PLCE1

6.68e-0518310359c2689d76fc6d30f5ab093428aa669d0a98953cf
ToppCellCOPD-Epithelial-Basal|COPD / Disease state, Lineage and Cell class

CACHD1 RIPK4 LOXL4 BCAM SDK1

6.68e-0518310350f760e393edc91009bf6c7e02eeac039a1dfb4ed
ToppCell3'-GW_trimst-1-LargeIntestine-Neuronal-Glial_immature-Glia_1_(DHH+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LGI4 METRN FAM210B FHDC1 HR

6.68e-051831035547b1fb9f9940cfc8d6e351d96acc0da44def57e
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-Proliferating_Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRIM46 PLA2G15 SORT1 HR TEDC1

6.68e-05183103542dc31d587fbb9724b2f0be5ee8ed77233f67b86
ToppCell3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_mature-Lymphatic_EC_mature_L.2.5.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PHF24 CARD10 RASIP1 KBTBD11 SLC27A3

6.86e-0518410351a4297b9d3cc4744bea0408fd5ee7b33ba2a1d78
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ILDR2 SORT1 ZDHHC6 SMAD6 PLCE1

6.86e-0518410357294b379ce4cb8fa75e432559082f93cd106aaf5
ToppCelldroplet-Heart-4Chambers-21m-Endothelial-leukocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1A B3GALT6 KBTBD11 AP4M1 PLCE1

7.04e-051851035bb5a4cf93534b9bcd0923f314c389d571e91e7f8
ToppCellPCW_13-14-Hematologic_ErythroMegGranulo-Hem_ErythroMeg-erythro|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

PITHD1 TFR2 FAM210B PDIA2 FHDC1

7.22e-05186103534ed60e846fd83fab3e28dc9e278bcc4b092a9f0
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SPEG LGI4 ADGRA2 SDK1 PLCE1

7.78e-0518910357fbe855bfdb47d35e040b04a80fe4b729a3764e8
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SPEG LGI4 ADGRA2 SDK1 PLCE1

7.78e-05189103506b35abecd29f902cf251fcc1f6ad33db7ab08a2
ToppCelldroplet-Limb_Muscle-Pre-Sort-18m-Mesenchymal-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IRS4 SPEG SORT1 FAT2 BCAM

8.18e-05191103560bc1f3efa7bbad5cb7944fe5e049ea79cd1745a
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SPEG ADGRA2 SORT1 SDK1 PLCE1

8.38e-051921035bfab13793e54de2550ee171397f7ece0625cdb4a
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SPEG ADGRA2 SORT1 SDK1 PLCE1

8.38e-051921035b54b0d5b88139905521c8d5d58332e89c08d589c
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SPEG LGI4 SORT1 SDK1 PLCE1

8.80e-0519410355c3b2b05d1e4f146551fe4c920263d8e6ca34de3
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SPEG LGI4 SORT1 SDK1 PLCE1

8.80e-051941035ab9cad697f9209d2889bc02b43b502dfeb2ebfef
ToppCelldroplet-Heart-HEART-1m-Mesenchymal-cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPEG CSDC2 XIRP2 IGSF1 ALDH1B1

9.23e-051961035a582130862bee76c0385156a333bfdfc75cf218b
ToppCelldroplet-Heart-HEART-1m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPEG CSDC2 XIRP2 IGSF1 ALDH1B1

9.23e-051961035fba52a4b82086dbae9a55038bf44c4539be926f5
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-Basal_1|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

TRIM46 RIPK4 PLEKHG4B FAT2 VWA2

9.46e-051971035751f19b00f92e1334f653b870d3f7c0c149ff41a
ToppCelldistal-3-Epithelial-Basal|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CACHD1 RIPK4 FAT2 LOXL4 BCAM

9.46e-05197103572ac9068cfd8f04c521a858d55eb8b5764de0282
ToppCellParenchyma_Control_(B.)-Epithelial-TX-Basal_1|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

TRIM46 RIPK4 PLEKHG4B FAT2 VWA2

9.46e-0519710352701864e49878c5f323f5133e2c4b0a5a7fff7f5
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-Basal_1-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TRIM46 RIPK4 PLEKHG4B FAT2 VWA2

9.46e-05197103558d809ccb8cc4b1e76acf0b8f996cd0e2637290c
ToppCellTracheal-10x5prime-Stromal-Schwann-Schwann_nonmyelinating|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

LGI4 MIR1915HG AATK IGSF1 MYO15A

9.46e-051971035e239caae24f40564a24ad909754f5436f767ccdb
ToppCellTransplant_Alveoli_and_parenchyma-Mesenchymal-Smooth_muscle|Mesenchymal / Tissue, Lineage and Cell class of Lung Cells from 10X

SPEG LGI4 CSDC2 SORT1 BCAM

9.69e-05198103589986c7756541df364df516329d10775ba0e78a4
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_basal-Suprabasal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CACHD1 RIPK4 FAT2 SDK1 PLCE1

9.69e-05198103519d8ff3a4f911b13ecc34844202925475ad4d2ab
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_basal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CACHD1 RIPK4 FAT2 BCAM SDK1

9.69e-0519810355374b0e98d669f36a0571d3c006c7bd5e3c8e87f
ToppCelldistal-Epithelial-Basal-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CACHD1 RIPK4 FAT2 LOXL4 BCAM

9.69e-051981035dda0bf3a48f738df590ce23b891d82be19e10d66
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_basal-Basal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CACHD1 FAT2 LOXL4 BCAM SDK1

9.92e-05199103594a7867e800df352731796de8c24cba133c29622
ToppCellParenchyma_Control_(B.)-Stromal-TX-Smooth_muscle-2|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

SPEG LGI4 CSDC2 BCAM PLCE1

9.92e-051991035471738f2059e20407572d9c4cbd11812068333ea
ToppCellTracheal-10x5prime-Stromal-Myofibroblastic-Muscle_smooth_pulmonary|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

SPEG PHF24 LGI4 CSDC2 SORT1

9.92e-0519910358ff0fdcbe9661b013913731ec8b53d84836ca865
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Smooth_muscle-2|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

SPEG LGI4 CSDC2 BCAM PLCE1

9.92e-051991035706b7de777ff86eb22e538ccd5c2987ceb6be308
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Smooth_muscle-2-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SPEG LGI4 CSDC2 BCAM PLCE1

9.92e-051991035690a4f84b205532c4c9e5c19d5ae430d0655f421
ToppCellLung_Parenchyma-Severe-Hematopoietic-RBC-RBC|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

PITHD1 ABCB6 TFR2 FAM210B FHDC1

1.02e-042001035b5f2892bc45fda5ae05e269b840305a608a07c37
ToppCellLung_Parenchyma-Severe-Hematopoietic-RBC|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

PITHD1 ABCB6 TFR2 FAM210B FHDC1

1.02e-0420010359ce1f91991637fc3af0f6a80a85e1a44276fe412
ToppCellCOVID-19-COVID-19_Severe-Others-RBC|COVID-19_Severe / Disease, condition lineage and cell class

PITHD1 TFR2 FAM210B FHDC1 BCAM

1.02e-042001035308f74e7e13ecc6d133c219c42cc8895a96644c8
ToppCellLung_Parenchyma-Control-Endothelial-Endothelial-Lymphatic-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PHF24 CARD10 CEP68 RASIP1 KBTBD11

1.02e-042001035f99d0d3f51b4893fa7898c5b435494358a654cbd
ToppCellLung_Parenchyma-Control-Endothelial-Endothelial-Lymphatic|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

PHF24 CARD10 CEP68 RASIP1 KBTBD11

1.02e-042001035e65d4ae3d48f68c12edd5dc2c2f4e25e4acfadf1
ToppCellParenchyma_Control_(B.)-Endothelial-TX-Lymphatic|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

PHF24 CARD10 CEP68 RASIP1 KBTBD11

1.02e-0420010354ec8e30dd241d83a1bba1c5967b6a4656afbfafd
ToppCellLung_Parenchyma-Severe-Hematopoietic|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

PITHD1 ABCB6 TFR2 FAM210B FHDC1

1.02e-042001035fdf3e60cf94f398a56c0fa72813d0459f5ce081b
ToppCellLung_Parenchyma-Severe-Hematopoietic-RBC-RBC-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PITHD1 ABCB6 TFR2 FAM210B FHDC1

1.02e-042001035199165be1aef8497af71b74690a11de18fbe073c
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Macroglial-oligodendrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RALGDS APBB1 SORT1 AATK MAST3

1.02e-042001035e5b4821fff40566c4a7dc3f74a14e27eb06b165d
ToppCellParenchyma_COVID-19-Stromal-TX-Erythrocytes|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

PITHD1 ABCB6 TFR2 FAM210B FHDC1

1.02e-042001035a9edac2f5e009662df452ec032a80e855cdac28f
ToppCellSubstantia_nigra|World / BrainAtlas - Mouse McCarroll V32

IRS4 CACHD1 XIRP2 IGSF1

1.47e-04115103418174b8d57d444fab1e9d2b13d22939c83c958e0
ToppCellmild_COVID-19-RBC|World / disease group, cell group and cell class (v2)

PITHD1 APBB1 FAM210B BCAM

1.57e-04117103485210be67ddc31903764b7fa6d7029d9656753d3
DrugPhenacetin [62-44-2]; Up 200; 22.4uM; HL60; HT_HG-U133A

TBC1D30 SPEG CARD10 TFR2 BMP1 DLG4 PLCE1 TJP3

3.46e-0619910382471_UP
DiseaseCharcot-Marie-Tooth disease (biomarker_via_orthology)

GSTT2B GSTT2

1.11e-052992DOID:10595 (biomarker_via_orthology)
Diseasephosphatidylcholine 34:2 measurement

CACNA1A MAST2 SMAD6

4.01e-0520993EFO_0010376
DiseaseOvarian Mucinous Adenocarcinoma

SPEG MAST2 AATK

1.54e-0431993C1335167
Diseasecancer antigen 15.3 measurement

TRIM46 MTX1

2.31e-047992EFO_0010585
DiseaseIgG fucosylation measurement

NDUFAF8 TEDC1

4.93e-0410992EFO_0008427
Diseasenephritis (biomarker_via_orthology)

SMAD6 SMAD7

6.01e-0411992DOID:10952 (biomarker_via_orthology)
Disease3-formylindole measurement

GSTT2B GSTT2

8.48e-0413992EFO_0801025
DiseaseAbdominal Aortic Aneurysm

CHRNB4 ABHD16B ALDH1B1

1.57e-0368993EFO_0004214
Diseasehematocrit

TRIM46 MAST2 TFR2 MRPS18A ABHD16B SMG9 DLG4 MTX1 SMAD6 SMAD7

2.12e-0310119910EFO_0004348

Protein segments in the cluster

PeptideGeneStartEntry
VAIPRDFWLRSSGRF

CHRNB4

406

P30926
GRARARDQRWSRSPS

CACNA1A

2236

O00555
GPRASREEGTFWTER

nan

61

P0DMU3
IRSTWLARRGAPGDV

B3GALT6

76

Q96L58
SWVERRDFRGQARPA

BTNL10

176

A8MVZ5
DRWSGAVVRRVLSGP

CARD10

626

Q9BWT7
RFPRGVSRSLWDVFA

CNTNAP1

186

P78357
PRAPGSRDARWERRE

CEP68

401

Q76N32
NRGDFRWPRTLAGIT

ADGRA2

361

Q96PE1
KAAREAFRLGSPWRR

ALDH1B1

81

P30837
AHSPERRRRYWGRSG

CACHD1

1176

Q5VU97
DEWRRGGEPRRGFSD

CFAP46

2546

Q8IYW2
RRRERPAGADSLSWG

ABCB6

51

Q9NP58
RVWGVGRDSGRERDF

APBB1

451

O00213
EVRDGFWRKAPLRGR

BMP1

381

P13497
AREGRAVVTRWLRAG

ABHD16B

361

Q9H3Z7
FRLFPSVQWDRGSGR

AP4M1

296

O00189
PGWARRFELRGREEA

RASIP1

246

Q5U651
FDKPGAERSWRRRAA

RBM33

21

Q96EV2
TRGEDVRGAPYDWRR

PLA2G15

151

Q8NCC3
SSRGAGWRRPELSSR

FHDC1

911

Q9C0D6
TAERRRGWRCRGVPT

MIR1915HG

11

Q5T4H9
LGRTDFRPKTGRDSW

LOXL4

591

Q96JB6
RASRGPIAFWARRAS

MAGED2

216

Q9UNF1
GRCVRWGPRERRALF

METRN

116

Q9UJH8
ELRRRGPDFGWRFGT

MYO15A

2921

Q9UKN7
RFVWGRTRLPRTIAD

HERC2

4721

O95714
DAGLRRRLREEWGVS

HR

1091

O43593
RSFRWRDASGPRERL

ISM2

451

Q6H9L7
FRVRASDWGSPFRRE

FAT2

531

Q9NYQ8
LSRSWLRSGEGPRRE

MYO18A

316

Q92614
AGRVGARVRPRATWL

FAM210B

11

Q96KR6
GRQRGDFSLWLRPAR

LAG3

126

P18627
DFSLWLRPARRADAG

LAG3

131

P18627
WGRSRAREAPVGALT

MROH6

6

A6NGR9
GPRDAEGIAEWLRRR

PDIA2

136

Q13087
SWGTGRAVARIPRVR

RPL4

66

P36578
PRRGAYEWGVRSTRK

MRPL37

26

Q9BZE1
GRPRLAAWRGRVEAF

GSTT2B

186

P0CG30
RDFRGVSRRTGEEWL

MVP

236

Q14764
GSWVSADGFLRRRPS

PRPF40A

41

O75400
ERARRGSSALWVPAG

NTN3

496

O00634
WTRRAEGPREGTFAE

LINC00482

126

Q8N8I6
WPRLRTRGSETDGRD

IGSF1

1286

Q8N6C5
RFSRRGADDDRPSWR

EIF3A

976

Q14152
RPPRRGLDEDRGSWR

EIF3A

1016

Q14152
RGSWRTADEDRGPRR

EIF3A

1026

Q14152
AAGRRRQAPWREFTG

LINC00473

6

A8K010
SRGKAREGRSPTRWA

C3orf20

646

Q8ND61
GRPRLAAWRGRVEAF

GSTT2

186

P0CG29
RLFSIGRSVEGRPLW

CPD

81

O75976
GFIPSKRRVERREWS

DLG4

486

P78352
AEPLFPGSRRSRSVW

RALGDS

16

Q12967
FSFVPARRTDGRRWS

MAST2

216

Q6P0Q8
ARRADGRRWSLASLP

MAST3

76

O60307
PFHREGSRVWERGGV

CSDC2

26

Q9Y534
WFLTDRSGARPRLAS

BCAM

66

P50895
GPWSEVVRGRTRESV

SDK1

1261

Q7Z5N4
RFLVSDRFWVRGEGP

DPP7

56

Q9UHL4
FWGRQVLRRSAGRAP

JADE3

746

Q92613
LEPGGWLRRSRFEQF

IRS4

366

O14654
GVRGSTWTRRRDSPR

MTX1

51

Q13505
TWTRRRDSPRRAGPT

MTX1

56

Q13505
REGPTFRRDRERESW

RBM6

631

P78332
RRTLLGVAGGWRRFE

MRPL46

6

Q9H2W6
RGGRWRRSAPGEDEE

SORT1

71

Q99523
GPTRWQRREEVRGTS

TRIM46

476

Q7Z4K8
RRLWRSRVVPDREEG

SMAD6

11

O43541
AGAERPRRRGRLWDS

SNAP47

11

Q5SQN1
AEEEFERRWRSLRPG

AATK

406

Q6ZMQ8
RPVLFHWTGGRFERR

LGI4

386

Q8N135
AVWGRVRSRLRAFPE

NDUFAF8

6

A1L188
VELFGGRRWSARNPS

PLCE1

1046

Q9P212
RRWGEVTGRRPQLFT

FBXL18

666

Q96ME1
LYGIERRRRWKEPGS

SMG9

11

Q9H0W8
SWSRLPARGFREVVE

MRPS18A

26

Q9NVS2
ERARPGAWRRDIFGR

MRPL47

161

Q9HD33
RAAWERLRDGRGVEP

PHF24

76

Q9UPV7
VTGRWRSPGEGFRLE

RIPK4

296

P57078
SRAGTWRFQPAREGE

KBTBD11

566

O94819
QPERRFFRRGWVTFD

SRRT

456

Q9BXP5
PTWPRSREREAAAFR

CTSO

31

P43234
TRREPWIGLRRVGDE

CLEC2L

151

P0C7M8
PRQERSRARGWAGVE

C11orf68

21

Q9H3H3
RGDVRSCRWLFETRP

XIRP2

836

A4UGR9
SFIEGVSRIRGWFPR

ZDHHC6

376

Q9H6R6
ERRRPGRRWSVSIDE

TEX22

56

C9J3V5
RRLWRSRAPGGEDEE

SMAD7

11

O15105
RERRDAGRRTTWSPQ

ZPLD1

316

Q8TCW7
DRGFPPRRELSGWLR

TJP2

6

Q9UDY2
GRSRSWEDSPERGRP

TJP2

166

Q9UDY2
WRGFSTSAVLGRRTP

MRPL38

16

Q96DV4
GDRGPRAVFLLTRWR

TRPM5

711

Q9NZQ8
SRSRLRWGFSRPRKD

SPEG

2541

Q15772
GSGLRPDTWERFVRR

SLC27A3

401

Q5K4L6
ADRGWAFSPARRRPA

ILDR2

491

Q71H61
GRGVFKPWEERTDRS

PITHD1

51

Q9GZP4
GAAGRTLPRRSRSWE

PLEKHG4B

71

Q96PX9
VGDSGLRFEIWFRRR

PLEKHG4B

1061

Q96PX9
GRGPEWSAARRASRE

TEDC1

391

Q86SX3
APGGRWRSRRVFLLV

TUG1

46

A0A6I8PU40
RGVTVFAVGVRFPRW

VWA2

176

Q5GFL6
VARKERGWRTVFPSR

MRPL18

61

Q9H0U6
RESWRRAARTAPVAG

PRRT4

551

C9JH25
RGAAERPRRSRDTWD

TBC1D30

46

Q9Y2I9
IPSGAGREWLERRRA

RABAC1

26

Q9UI14
SGSGRSWDERSRRPR

TJP3

136

O95049
PDGVRFDRERARRLW

ZNF346

31

Q9UL40
RPRRSLLFISWDGGD

TFR2

466

Q9UP52
GRERPLRAGESWFLV

USP11

91

P51784
LEAATRAWRGLRERG

KIAA2013

66

Q8IYS2