Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionRab GDP-dissociation inhibitor activity

GDI1 GDI2

1.63e-052812GO:0005093
GeneOntologyMolecularFunctionGTP-dependent protein kinase activity

BRD4 LRRK2

1.63e-052812GO:0034211
GeneOntologyMolecularFunctiondATP binding

ST13P5 ST13

1.61e-045812GO:0032564
GeneOntologyMolecularFunctionadenyl deoxyribonucleotide binding

ST13P5 ST13

2.41e-046812GO:0032558
GeneOntologyMolecularFunctionpurine deoxyribonucleotide binding

ST13P5 ST13

3.37e-047812GO:0032554
GeneOntologyMolecularFunctionmitogen-activated protein kinase binding

MAPK14 PLCB4 PRKG2

3.83e-0435813GO:0051019
GeneOntologyMolecularFunctiondeoxyribonucleotide binding

ST13P5 ST13

5.74e-049812GO:0032552
DomainRabGDI

GDI1 GDI2

1.86e-052812IPR000806
DomainGDI

GDI1 GDI2

1.11e-044812PF00996
DomainGDP_dissociation_inhibitor

GDI1 GDI2

1.11e-044812IPR018203
DomainTPR

TOMM70 TRANK1 IFT88 ST13P5 ST13

2.45e-04129815SM00028
DomainTPR-contain_dom

TOMM70 TRANK1 IFT88 ST13P5 ST13

4.90e-04150815IPR013026
DomainTPR-like_helical_dom

TOMM70 TRANK1 IFT88 KDM6B ST13P5 ST13

5.26e-04233816IPR011990
DomainTPR_1

TOMM70 IFT88 ST13P5 ST13

6.32e-0490814PF00515
DomainTPR_1

TOMM70 IFT88 ST13P5 ST13

6.32e-0490814IPR001440
DomainTPR_REGION

TOMM70 TRANK1 IFT88 ST13P5 ST13

7.55e-04165815PS50293
DomainTPR

TOMM70 TRANK1 IFT88 ST13P5 ST13

7.55e-04165815PS50005
DomainLeu-rich_rpt_4

LRRK2 NLRC5

8.17e-0410812IPR025875
DomainLRR_4

LRRK2 NLRC5

8.17e-0410812PF12799
DomainSTI1

ST13P5 ST13

8.17e-0410812SM00727
DomainSTI1_HS-bd

ST13P5 ST13

8.17e-0410812IPR006636
DomainTPR_8

TOMM70 IFT88 ST13

1.57e-0353813PF13181
DomainGPCR_3_CS

GPRC6A GABBR2

1.63e-0314812IPR017979
Domain-

TOMM70 TRANK1 IFT88 KDM6B ST13

2.06e-032078151.25.40.10
DomainTPR_repeat

TOMM70 TRANK1 IFT88 ST13

2.68e-03133814IPR019734
DomainGPCR_3

GPRC6A GABBR2

3.70e-0321812IPR000337
Domain7tm_3

GPRC6A GABBR2

4.06e-0322812PF00003
DomainG_PROTEIN_RECEP_F3_2

GPRC6A GABBR2

4.06e-0322812PS00980
DomainG_PROTEIN_RECEP_F3_3

GPRC6A GABBR2

4.06e-0322812PS00981
DomainG_PROTEIN_RECEP_F3_1

GPRC6A GABBR2

4.06e-0322812PS00979
DomainG_PROTEIN_RECEP_F3_4

GPRC6A GABBR2

4.06e-0322812PS50259
DomainGPCR_3_C

GPRC6A GABBR2

4.06e-0322812IPR017978
Pubmed

Crosstalk between Nodal/activin and MAPK p38 signaling is essential for anterior-posterior axis specification.

SUPT20HL1 MAPK14 SUPT20HL2

7.54e-07884321802298
Pubmed

KSHV episome tethering sites on host chromosomes and regulation of latency-lytic switch by CHD4.

NCOR2 RBM27 WDR33 BRD4 UBR4 HNRNPL

7.77e-0713084635545047
Pubmed

Cloning of a brain-type isoform of human Rab GDI and its expression in human neuroblastoma cell lines and tumor specimens.

GDI1 GDI2

5.76e-0628427585614
Pubmed

St13 protects against disordered acinar cell arachidonic acid pathway in chronic pancreatitis.

ST13P5 ST13

5.76e-06284235562743
Pubmed

NLRC5 exerts anti-endometriosis effects through inhibiting ERβ-mediated inflammatory response.

ESR2 NLRC5

5.76e-06284239218863
Pubmed

Interaction proteomics analysis of polycomb proteins defines distinct PRC1 complexes in mammalian cells.

NCOR2 IGF2BP2 TRANK1 NBN NOP2

9.47e-0611684521282530
Pubmed

Comprehensive analysis of DNA repair gene variants and risk of meningioma.

BRIP1 POLG WRN NBN

1.13e-055784418270339
Pubmed

A High-Density Human Mitochondrial Proximity Interaction Network.

TOMM70 IGF2BP2 WDR33 NDUFAF7 SEC24A POLG DDX18 UBR4 PSMB3 ITPRID2 NOP2 GDI2 ST13 HNRNPL

1.32e-051496841432877691
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

POLR1D NCOR2 IGF2BP2 RBM27 BRD4 PSMB3 PYGL BICRAL NOP2 GDI2 TFAP2A HNRNPL

1.35e-051103841234189442
Pubmed

Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation.

NCOR2 RBM27 WDR33 SEC24A PSMB3 NUP58 TFAP2A MAML3

1.52e-0545784832344865
Pubmed

Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 Using Proximity Labeling and Affinity Purification.

BRIP1 BRD4 DDX18 WRN NBN ZNF518A

1.70e-0522284637071664
Pubmed

Werner syndrome protein associates with gamma H2AX in a manner that depends upon Nbs1.

WRN NBN

1.73e-05384215733840
Pubmed

RabGDIα is a negative regulator of interferon-γ-inducible GTPase-dependent cell-autonomous immunity to Toxoplasma gondii.

GDI1 GDI2

1.73e-05384226240314
Pubmed

Neprilysin Is Required for Angiotensin-(1-7)'s Ability to Enhance Insulin Secretion via Its Proteolytic Activity to Generate Angiotensin-(1-2).

GPRC6A MME

1.73e-05384228559246
Pubmed

Expression patterns of two human genes coding for different rab GDP-dissociation inhibitors (GDIs), extremely conserved proteins involved in cellular transport.

GDI1 GDI2

1.73e-0538427543319
Pubmed

Linkage between Werner syndrome protein and the Mre11 complex via Nbs1.

WRN NBN

1.73e-05384215026416
Pubmed

Estrogen receptorβ2 regulates interlukin-12 receptorβ2 expression via p38 mitogen-activated protein kinase signaling and inhibits non-small-cell lung cancer proliferation and invasion.

MAPK14 ESR2

1.73e-05384225695486
Pubmed

Cloning, characterization, and expression of a novel GDP dissociation inhibitor isoform from skeletal muscle.

GDI1 GDI2

1.73e-0538427513052
Pubmed

The p38-interacting protein (p38IP) regulates G2/M progression by promoting α-tubulin acetylation via inhibiting ubiquitination-induced degradation of the acetyltransferase GCN5.

SUPT20HL1 SUPT20HL2

1.73e-05384224220028
Pubmed

A positive feedback loop between Periostin and TGFβ1 induces and maintains the stemness of hepatocellular carcinoma cells via AP-2α activation.

POSTN TFAP2A

1.73e-05384234193219
Pubmed

ATM phosphorylation of Nijmegen breakage syndrome protein is required in a DNA damage response.

WRN NBN

1.73e-05384210839545
Pubmed

Cripto is required for mesoderm and endoderm cell allocation during mouse gastrulation.

SUPT20HL1 MAPK14 SUPT20HL2

1.75e-052184323747598
Pubmed

Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.

POLR1D WDR33 SENP3 UBR4 NBN GREB1 NOP2

1.94e-0534184732971831
Pubmed

p38 and a p38-interacting protein are critical for downregulation of E-cadherin during mouse gastrulation.

SUPT20HL1 MAPK14 SUPT20HL2

2.02e-052284316751104
Pubmed

Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.

TOMM70 NCOR2 IGF2BP2 DDX18 UBR4 PSMB3 PYGL FRYL NOP2 GDI1 GDI2 ST13 HNRNPL

2.36e-051367841332687490
Pubmed

SARS-CoV-2 N Protein Antagonizes Stress Granule Assembly and IFN Production by Interacting with G3BPs to Facilitate Viral Replication.

NCOR2 IGF2BP2 RBM27 DDX18 SENP3 HNRNPL

2.95e-0524584635652658
Pubmed

DUB3 Promotes BET Inhibitor Resistance and Cancer Progression by Deubiquitinating BRD4.

NCOR2 BRD4

3.45e-05484230057199
Pubmed

WRN participates in translesion synthesis pathway through interaction with NBS1.

WRN NBN

3.45e-05484220600238
Pubmed

The Parkinson's disease associated LRRK2 exhibits weaker in vitro phosphorylation of 4E-BP compared to autophosphorylation.

MAPK14 LRRK2

3.45e-05484220090955
Pubmed

Genomic interaction between ER and HMGB2 identifies DDX18 as a novel driver of endocrine resistance in breast cancer cells.

ESR2 DDX18

3.45e-05484225284587
Pubmed

Selective hormone-dependent repression of estrogen receptor beta by a p38-activated ErbB2/ErbB3 pathway.

MAPK14 ESR2

3.45e-05484215862947
Pubmed

C-Jun NH2-Terminal Kinase and p38 Inhibition Suppresses Prostaglandin E2-Stimulated Aromatase and Estrogen Receptor Levels in Human Endometriosis.

MAPK14 ESR2

3.45e-05484226394174
Pubmed

Human transcription factor protein interaction networks.

NCOR2 TSHZ3 IGF2BP2 RBM27 WDR33 SEC24A DDX18 UBR4 PSMB3 NBN FEV NOP2 HNRNPL

3.73e-051429841335140242
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

POSTN TOMM70 NCOR2 IGF2BP2 MAPK14 SEC24A FAM91A1 NBN ITPRID2 TFAP2A HNRNPL

4.44e-051049841127880917
Pubmed

Global mapping of herpesvirus-host protein complexes reveals a transcription strategy for late genes.

TOMM70 GLB1 RBM27 WDR33 BRD4 SENP3 XPNPEP3 ATP11C

4.54e-0553384825544563
Pubmed

Impact of lactobacilli on orally acquired listeriosis.

CES1 NLRC5 PYGL ST13P5 ST13

4.73e-0516284523012479
Pubmed

Identification and functional characterization of transcriptional activators in human cells.

TYK2 NCOR2 TSHZ3 BRD4 PYGL BICRAL ZNF518A

5.18e-0539884735016035
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

TYK2 NCOR2 POLG ANKAR ENTPD1 XPNPEP3 NLRC5 FRYL PLCB4 GREB1 MME MAML3 HNRNPL

5.68e-051489841328611215
Pubmed

ERbeta Binds N-CoR in the Presence of Estrogens via an LXXLL-like Motif in the N-CoR C-terminus.

NCOR2 ESR2

5.74e-05584212904255
Pubmed

GDI-1 preferably interacts with Rab10 in insulin-stimulated GLUT4 translocation.

GDI1 GDI2

5.74e-05584219570034
Pubmed

Characterization of novel Rab6-interacting proteins involved in endosome-to-TGN transport.

GDI1 GDI2

5.74e-05584211929610
Pubmed

Differential recruitment of coregulator proteins steroid receptor coactivator-1 and silencing mediator for retinoid and thyroid receptors to the estrogen receptor-estrogen response element by beta-estradiol and 4-hydroxytamoxifen in human breast cancer.

NCOR2 ESR2

5.74e-05584214715875
Pubmed

Fanconi anemia group J helicase and MRE11 nuclease interact to facilitate the DNA damage response.

BRIP1 NBN

5.74e-05584223530059
Pubmed

The many substrates and functions of ATM.

WRN NBN

5.74e-05584211252893
Pubmed

The expression of estrogen receptors as well as GREB1, c-MYC, and cyclin D1, estrogen-regulated genes implicated in proliferation, is increased in peritoneal endometriosis.

ESR2 GREB1

5.74e-05584222884659
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

UBR4 BICRAL FRYL ITPRID2

6.05e-058784412465718
Pubmed

Competitive binding of E3 ligases TRIM26 and WWP2 controls SOX2 in glioblastoma.

DDX18 XPNPEP3 PSMB3 WRN ITPRID2 NOP2 GDI1 GDI2 HNRNPL

6.96e-0573284934732716
Pubmed

An inducible CRISPR/Cas9 screen identifies DTX2 as a transcriptional regulator of human telomerase.

NCOR2 RBM27 WDR33 NUP58 TFAP2A

7.79e-0518084535198878
Pubmed

The hematopoiesis-specific GTP-binding protein RhoH is GTPase deficient and modulates activities of other Rho GTPases by an inhibitory function.

GDI1 GDI2

8.59e-05684211809807
Pubmed

Polymorphisms in genes involved in DNA double-strand break repair pathway and susceptibility to benzene-induced hematotoxicity.

WRN NBN

8.59e-05684216728435
Pubmed

A field synopsis on low-penetrance variants in DNA repair genes and cancer susceptibility.

BRIP1 WRN NBN

9.95e-053784319116388
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

NCOR2 BRIP1 RBM27 WDR33 BRD4 DDX18 NBN NOP2 TFAP2A HNRNPL

1.01e-04954841036373674
Pubmed

A tissue-specific role for intraflagellar transport genes during craniofacial development.

IFT88 TFAP2A

1.20e-04784228346501
Pubmed

LRRK2 impairs PINK1/Parkin-dependent mitophagy via its kinase activity: pathologic insights into Parkinson's disease.

TOMM70 LRRK2

1.20e-04784230629163
Pubmed

Evaluation of genetic variation in the double-strand break repair pathway and bladder cancer risk.

BRIP1 NBN

1.20e-04784217557904
Pubmed

Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

TRANK1 KDM6B ARHGEF17 ZNF518A

1.21e-041048449205841
Pubmed

Oct4 links multiple epigenetic pathways to the pluripotency network.

NCOR2 WDR33 BRD4 TFAP2A HNRNPL

1.37e-0420384522083510
Pubmed

Unique spatiotemporal requirements for intraflagellar transport genes during forebrain development.

IFT88 TFAP2A

1.60e-04884228291836
Pubmed

Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.

NCOR2 RBM27 BRD4 DDX18 UBR4 PSMB3 NBN PYGL GDI2 TFAP2A

1.67e-041014841032416067
Pubmed

Microsequences of 145 proteins recorded in the two-dimensional gel protein database of normal human epidermal keratinocytes.

PSMB3 GDI1 HNRNPL

1.79e-04458431286667
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

IGF2BP2 DDX18 UBR4 PYGL FRYL NOP2 GDI1 GDI2

1.84e-0465384822586326
Pubmed

HiPLA: High-throughput imaging proximity ligation assay.

NCOR2 BRD4 NBN

1.91e-044684330419336
Pubmed

Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells.

POLR1D TOMM70 NCOR2 BRD4 DDX18 UBR4 PYGL HNRNPL

2.08e-0466584830457570
Pubmed

Full activation of estrogen receptor alpha activation function-1 induces proliferation of breast cancer cells.

NCOR2 ESR2

2.56e-041084212738788
Pubmed

Induction of collagen by estradiol: difference between sun-protected and photodamaged human skin in vivo.

ESR2 GREB1

2.56e-041084218794456
Pubmed

A balance between elongation and trimming regulates telomere stability in stem cells.

WRN NBN

2.56e-041084227918544
Pubmed

HIV-1 Vif promotes the G₁- to S-phase cell-cycle transition.

BRD4 HNRNPL

2.56e-041084221149631
Pubmed

TBX2 and TBX3 act downstream of canonical WNT signaling in patterning and differentiation of the mouse ureteric mesenchyme.

POSTN TSHZ3 MME

2.60e-045184330478225
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

NCOR2 RBM27 WDR33 BRD4 DDX18 SENP3 WRN NBN NOP2 TFAP2A HNRNPL

2.80e-041294841130804502
Pubmed

Modification of ovarian cancer risk by BRCA1/2-interacting genes in a multicenter cohort of BRCA1/2 mutation carriers.

BRIP1 NBN

3.13e-041184219584272
Pubmed

Glucagon regulates gluconeogenesis through KAT2B- and WDR5-mediated epigenetic effects.

SUPT20HL1 SUPT20HL2

3.13e-041184224051374
Pubmed

Phosphorylation of GSK-3beta by cGMP-dependent protein kinase II promotes hypertrophic differentiation of murine chondrocytes.

MAPK14 PRKG2

3.13e-041184218551195
Pubmed

Lineage-specific responses to reduced embryonic Pax3 expression levels.

POSTN TFAP2A

3.13e-041184218243171
Pubmed

Periostin as a biomarker of the amniotic membrane.

POSTN TFAP2A

3.13e-041184222966238
Pubmed

BPA modulates the WDR5/TET2 complex to regulate ERβ expression in eutopic endometrium and drives the development of endometriosis.

TOMM70 IGF2BP2 GLB1 ESR2 DDX18 UBR4 NOP2 HNRNPL

3.26e-0471184833022573
Pubmed

BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.

POLR1D IGF2BP2 RBM27 DDX18 SENP3 UBR4 WRN PYGL NOP2 ST13 HNRNPL

3.27e-041318841130463901
Pubmed

Cell cycle-dependent phosphorylation regulates RECQL4 pathway choice and ubiquitination in DNA double-strand break repair.

TSHZ3 IGF2BP2 MAPK14 IFT88 PSMB3 FAM91A1 NBN NOP2 GDI1 GDI2 HNRNPL

3.64e-041335841129229926
Pubmed

Two distinct nuclear receptor-interaction domains and CREB-binding protein-dependent transactivation function of activating signal cointegrator-2.

NCOR2 ESR2

3.75e-041284211158331
Pubmed

Regulation of cochlear convergent extension by the vertebrate planar cell polarity pathway is dependent on p120-catenin.

IFT88 PCDH15

3.75e-041284222318628
Pubmed

Suppression of HIV-1 Tat-induced monocyte adhesiveness by a cell-permeable superoxide dismutase in astrocytes.

MAPK14 ROS1

3.75e-041284218160848
Pubmed

Multifactorial contributions to an acute DNA damage response by BRCA1/BARD1-containing complexes.

BRIP1 NBN

3.75e-041284216391231
Pubmed

A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB.

NCOR2 TSHZ3 FAM91A1

3.81e-045884319734545
Pubmed

WDR76 Co-Localizes with Heterochromatin Related Proteins and Rapidly Responds to DNA Damage.

RBM27 WDR33 BRD4 DDX18 SENP3 NBN

3.93e-0439484627248496
Pubmed

Common single-nucleotide polymorphisms in DNA double-strand break repair genes and breast cancer risk.

BRIP1 NBN

4.42e-041384219064565
Pubmed

BRCA1 tumor suppressor network: focusing on its tail.

BRIP1 NBN

4.42e-041384222369660
Pubmed

Tumor suppressor BAP1 nuclear import is governed by transportin-1.

IGF2BP2 RBM27 UBR4 XPNPEP3 PSMB3 PYGL GDI1 GDI2 ST13 HNRNPL

4.49e-041149841035446349
Pubmed

HIV-1 Vpr induces cell cycle arrest and enhances viral gene expression by depleting CCDC137.

RBM27 BRD4 NOP2 HNRNPL

4.66e-0414884432538781
Pubmed

Deletion of the Ste20-like kinase SLK in skeletal muscle results in a progressive myopathy and muscle weakness.

POSTN MAPK14

5.15e-041484228153048
Pubmed

A large-scale candidate gene association study of age at menarche and age at natural menopause.

MAPK14 POLG ESR2 NBN GABBR2

5.53e-0427584520734064
Pubmed

A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.

TYK2 TOMM70 IGF2BP2 MAPK14 UBR4 PSMB3 PYGL NOP2 HNRNPL

5.75e-0497484928675297
Pubmed

Nuclear receptor coactivator ACTR is a novel histone acetyltransferase and forms a multimeric activation complex with P/CAF and CBP/p300.

NCOR2 ESR2

5.93e-04158429267036
Pubmed

Protein kinase C-delta (PKC-delta ) is activated by type I interferons and mediates phosphorylation of Stat1 on serine 727.

TYK2 MAPK14

5.93e-041584211839738
Pubmed

The HECT type ubiquitin ligase NEDL2 is degraded by anaphase-promoting complex/cyclosome (APC/C)-Cdh1, and its tight regulation maintains the metaphase to anaphase transition.

SENP3 PSMB3 ASTE1 EGFLAM TFAP2A

6.09e-0428184524163370
Pubmed

Mapping the Ku Interactome Using Proximity-Dependent Biotin Identification in Human Cells.

RBM27 BRD4 WRN NOP2 ST13

6.29e-0428384530585729
Pubmed

A protein-RNA interaction atlas of the ribosome biogenesis factor AATF.

IGF2BP2 DDX18 NOP2 HNRNPL

6.55e-0416284431363146
Pubmed

New Noonan syndrome model mice with RIT1 mutation exhibit cardiac hypertrophy and susceptibility to β-adrenergic stimulation-induced cardiac fibrosis.

POSTN MAPK14

6.77e-041684230898653
Pubmed

Variation within DNA repair pathway genes and risk of multiple sclerosis.

POLG WRN NBN

7.19e-047284320522537
Pubmed

Jmjd3 Plays Pivotal Roles in the Proper Development of Early-Born Retinal Lineages: Amacrine, Horizontal, and Retinal Ganglion Cells.

KDM6B TFAP2A

7.66e-041784232986815
Pubmed

Multiple essential roles for primary cilia in heart development.

IFT88 TFAP2A

7.66e-041784223351706
Pubmed

Smad5 determines murine amnion fate through the control of bone morphogenetic protein expression and signalling levels.

POSTN TFAP2A

8.60e-041884216887830
InteractionATRX interactions

RBM27 WDR33 ESR2 BRD4 LRRK2 WRN NBN FEV TFAP2A HNRNPL

8.03e-082677810int:ATRX
InteractionPOU5F1 interactions

NCOR2 MAPK14 RBM27 WDR33 BRD4 UBR4 LRRK2 PCDH15 NBN TFAP2A HNRNPL

1.48e-055847811int:POU5F1
InteractionOR5AC2 interactions

OR5AC2 ESR2

1.48e-052782int:OR5AC2
InteractionNFIC interactions

NCOR2 MAPK14 SEC24A ESR2 BRD4 FEV HNRNPL

1.70e-05210787int:NFIC
InteractionDNAJB4 interactions

POLR1D GLB1 ESR2 BRD4 GDI2 ST13

2.10e-05145786int:DNAJB4
InteractionTNFRSF13B interactions

TYK2 TRPM3 RBM27 SENP3

2.74e-0545784int:TNFRSF13B
InteractionNUP35 interactions

NCOR2 RBM27 WDR33 SEC24A ESR2 PSMB3 NUP58 TFAP2A MAML3

3.75e-05424789int:NUP35
InteractionST13P4 interactions

BRD4 ST13P5 ST13

5.17e-0519783int:ST13P4
GeneFamilyTetratricopeptide repeat domain containing|Bardet-Biedl syndrome associated|BBSome

TOMM70 TRANK1 IFT88 ST13

6.93e-04115634769
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

POSTN TRPM3 PYGL ATP11C ARHGEF17 MAML3

7.87e-0717282608a3fe536b1b064c5ee7779bc2b1115a5963a26b
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

POSTN TRPM3 PYGL ATP11C ARHGEF17 MAML3

7.87e-07172826553701349444eb366df3c11f54bb093434f153c6
ToppCellhuman_hepatoblastoma-Tumor_cells-T6|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

TRPM3 ESR2 ENTPD1 EGFLAM PLCB4 MAML3

9.94e-0717982614fc8ccb6b215063d747643f47d780d2b237eb67
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

POSTN ATP11C ARHGEF17 MUCL3 MAML3

1.13e-051598255ca96db4281abb5f646150ccf36adc66ab201c78
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

POSTN PYGL ATP11C ARHGEF17 MAML3

1.32e-05164825b6df1e67a5ce5f2d86f4e1420f4ee931f760bf4d
ToppCell3'_v3-lymph-node_spleen-Hematopoietic_progenitors-Progenitor|lymph-node_spleen / Manually curated celltypes from each tissue

IGF2BP2 FEV MME ARHGEF17 MAML3

1.44e-05167825cb396f3edb9e8fdc316091e8e193dbba50e0be0c
ToppCellInfluenza_Severe-Neutrophil|World / Disease group and Cell class

UBQLNL MAPK14 LRRK2 PYGL MME

1.52e-051698256e8e2580e19c96bcf7fa6a6d8c183df65f428396
ToppCell3'-GW_trimst-1.5-SmallIntestine-Neuronal-Glial_immature-Glia_1_(DHH+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TRPM3 HEATR4 LRRK2 EGFLAM TFAP2A

1.75e-05174825667035a11b68745fa8446d6c68214713be42710f
ToppCellPCW_05-06-Neuronal-Neuronal_SCP-neuro_pre_proliferating_SCP_(4)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

POSTN TRPM3 EGFLAM PLCB4 TFAP2A

1.90e-0517782559726bfd98f656fdcedf448a7e2e76a9bfad8285
ToppCellPCW_05-06-Neuronal-Neuronal_SCP|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

POSTN TRPM3 EGFLAM PLCB4 TFAP2A

2.17e-05182825b4fc5e4f5d8440a3c9ee0a6fd0da87b43cabc8c6
ToppCellcellseq2-Immune-Hematopoietic-Granulocytic-Neutrophil|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MAPK14 LRRK2 PYGL MME KDM6B

2.17e-051828251932d77491d6d46278f01fd70eb469ef1b356619
ToppCellcellseq2-Immune-Hematopoietic-Granulocytic|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MAPK14 LRRK2 PYGL MME KDM6B

2.23e-05183825cfbf8539104cef9ca830ad4f6bb278746f7078f7
ToppCellcellseq2-Immune-Hematopoietic|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MAPK14 LRRK2 PYGL MME KDM6B

2.23e-05183825324ec4374b552da7ce03809945b3a0798342d4ba
ToppCellPCW_05-06-Neuronal-Neuronal_SCP-neuro_proliferating_SCP1_(1)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

POSTN TRPM3 EGFLAM PLCB4 TFAP2A

2.35e-05185825a8946379fc066903fe8f4bc9cbf693b7b424a0cd
ToppCellpdx|World / Sample and Cell Type and Tumor Cluster (all cells)

IGF2BP2 BRIP1 PLCB4 GREB1 MAML3

2.41e-05186825de8e538c8767d41b8a52f5e58ba1affd4e7244c4
ToppCell356C-Lymphocytic-CD4_T-cell-Proliferating_T_cell|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

IGF2BP2 PYGL PLCB4 PRKG2 MAML3

2.41e-05186825722da08cd978249a19855fd3ec8ddda780c99d83
ToppCellpdx-Tumor_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

IGF2BP2 BRIP1 PLCB4 GREB1 MAML3

2.41e-051868250b88a87158a9ca8de3bf40a4ff1687150707a5f0
ToppCellPCW_05-06-Neuronal|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

POSTN TRPM3 EGFLAM PLCB4 TFAP2A

2.48e-0518782503a2ed85b171c887d4f3b0f4fe2e1cb4a853e658
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-Mesenchymal|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

POSTN LRRK2 PYGL EGFLAM TFAP2A

2.88e-05193825e1de67ddada87229f5db0ec193a6da8745a86a64
ToppCellsevere-Myeloid-Neutrophils_3|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

MAPK14 ENTPD1 LRRK2 PYGL MME

2.88e-05193825f4d43dfbf4115dd0f843ea5cf08049220342a047
ToppCellcontrol-Myeloid-Neutrophils_3|control / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

MAPK14 ENTPD1 LRRK2 PYGL MME

2.88e-0519382556daf3c59a124dd068af5409113913d9ee81a454
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-Mesenchymal-choroid_plexus/mesenchymal-like_cells|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

POSTN LRRK2 PYGL EGFLAM TFAP2A

2.88e-05193825b6f5a85210e60798205eaf5884cdb540f549d08a
ToppCellControl-Classical_Monocyte|Control / Disease condition and Cell class

TSHZ3 CES1 ENTPD1 LRRK2 PYGL

2.95e-051948259e33e1b54b4114f9e6981819834bb796ed7192b5
ToppCellsevere-Myeloid-Neutrophils_3|severe / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

MAPK14 ENTPD1 LRRK2 PYGL MME

2.95e-051948251f8edab1c8ba48bc0114429ea47aab378b5830b7
ToppCellmild-Myeloid-Neutrophils_3|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

ENTPD1 LRRK2 PYGL MME KDM6B

3.02e-05195825a1cfed0092debcc003eff6a62508556b7664d5e1
ToppCellBL-critical-LOC-Myeloid-Neutrophil|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

LRRK2 NBN PYGL MME KDM6B

3.10e-05196825f64d7fed31e418c55fe946744d78c3cbecec9bbf
ToppCellcontrol-immature_Neutrophil|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

CES1 UBR4 FAM91A1 PYGL MAML3

3.10e-05196825e34fd3e7a5b1c22a81fd3208e6d58bdb846d51c4
ToppCellmild-Myeloid-Neutrophils_2|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

MAPK14 LRRK2 PYGL MME KDM6B

3.10e-05196825e9f30eb8a3915c3b2af009c832bff9b349b65ae5
ToppCell10x_3'_v3-blood_(10x_3'_v3)-myeloid-myeloid_granulocytic-neutrophil|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

MAPK14 LRRK2 PYGL MME KDM6B

3.41e-052008256beabd5bad042d4d65c89c2f537c7376230f7c08
ToppCell10x_3'_v3-blood_(10x_3'_v3)-myeloid-myeloid_granulocytic|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

MAPK14 LRRK2 PYGL MME KDM6B

3.41e-05200825026495aa7f1e7528a01d9199475cfc393677fc60
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Calb2_Necab1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ANKAR MME RXFP3 PRKG2

8.66e-0512682428fbe63f7bc628b32d8e86bf9e80657e776dd1cc
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligoastrocytoma-3|TCGA-Brain / Sample_Type by Project: Shred V9

ZNF438 UBR4 PCDH15 ZNF518A

1.13e-041358243351e8b9e417397c5fa9f856184ff24ce1a27242
ToppCellfacs-Trachea-18m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l20-23|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TRANK1 ESR2 ROS1 PLA2G4E

1.45e-04144824e9d62f202f0fa8747961036ef0eafed91fe8a42f
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM3 SENP3 ROS1 TFAP2A

1.74e-04151824f4f7156b2c0cfc78fd1841e07c9915d97ced561f
ToppCell390C-Lymphocytic-NK_cells-NK_cell_E|390C / Donor, Lineage, Cell class and subclass (all cells)

TYK2 SENP3 KDM6B FGD6

1.92e-0415582498d8432739965dd1ab77c899cb6321f7f05eaa46
ToppCellTCGA-Liver-Primary_Tumor-Hepatocellular_Carcinoma-Hepatocellular_Carcinoma-7|TCGA-Liver / Sample_Type by Project: Shred V9

TRPM3 SLC5A6 GREB1 MME

2.12e-0415982470288df54adab167c0f50675128619299077db11
ToppCellHippocampus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)|Hippocampus / BrainAtlas - Mouse McCarroll V32

SLC5A6 PLCB4 MME RXFP3

2.22e-04161824b81b346309f3facbfbebd91cae4c5b33c7bd24ef
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

POSTN TRPM3 ATP11C ARHGEF17

2.22e-041618241b805f77790aeb8a71b08bfac2fe2eed7343258f
ToppCellLPS-IL1RA-Epithelial_airway-Club_cells|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CES1 SERPINB11 MME TFAP2A

2.44e-041658241a114eacaab598f755a173a3fed842ba91f689dd
ToppCellLPS-IL1RA-Epithelial_airway-Club_cells-Airway|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CES1 SERPINB11 MME TFAP2A

2.44e-041658249cfd3c1d2c6d714fde83b90465f1f9741b0e50ce
ToppCell368C-Fibroblasts-Fibroblast-C_(Myofibroblast)-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

NDUFAF7 ASTE1 PCDH15 MME

2.61e-04168824c66a61d3ec711796313a2c6d2dc39aedbfc20afd
ToppCellhealthy_donor-Myeloid-Monocytic-Neutrophil|healthy_donor / Disease condition, Lineage, Cell class and subclass

LRRK2 PYGL MME KDM6B

2.61e-0416882404259f5a9b067cd1b5619e34591e4b2fccc18535
ToppCell3'-Adult-SmallIntestine-Epithelial-epithelial_progenitor_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RBM27 MTTP MME MUCL3

2.61e-041688244e2e4c88ada772e9ba6e72c9ae3a05c063e93318
ToppCellControl-Lymphoid-ILC_B|Lymphoid / Disease state, Lineage and Cell class

IGF2BP2 PLCB4 TTLL10 MAML3

2.61e-04168824d7118d39253ed9790908b850088ebfc5a86f4065
ToppCell368C-Fibroblasts-Fibroblast-C_(Myofibroblast)|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

NDUFAF7 ASTE1 PCDH15 MME

2.61e-0416882483b4f817d95daa15ae60668e789f97d8a3b2e6dd
ToppCell3'-Adult-SmallIntestine-Epithelial-epithelial_progenitor_cell-TA|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RBM27 MTTP MME MUCL3

2.61e-04168824ee4dab089adef2f47a9d39d91934523331a8b81c
ToppCellPCW_05-06-Neuronal-Neuronal_SCP-neuro_proliferating_SCP3_(1)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

POSTN PYGL EGFLAM TFAP2A

2.67e-04169824d9c3b22f62b882b8a2ea6fd9cf7afbe6d1775745
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

POSTN ATP11C ARHGEF17 MAML3

2.74e-04170824876b84740e15399bfff2b9c7f0b80fd759bbdb3f
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

POSTN ATP11C ARHGEF17 MAML3

2.74e-041708241f8738acf439d893880db7e1fdc9b3615ca00c39
ToppCell390C-Epithelial_cells-Epithelial-H_(AT1)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

POSTN TSHZ3 PLCB4 TFAP2A

2.86e-04172824bb542f6ca4eb8167129bc84ca1160a54fbb68731
ToppCell390C-Epithelial_cells-Epithelial-H_(AT1)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

POSTN TSHZ3 PLCB4 TFAP2A

2.86e-04172824aff37b9689b0d30ee7097d997d9588efc475c8fd
ToppCellPND28-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

POSTN EGFLAM GPRC6A ARHGEF17

2.92e-04173824f9d6e892d66f9b94e4d5beb9f5dec9b606bc868a
ToppCellPND28-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

POSTN EGFLAM GPRC6A ARHGEF17

2.92e-04173824cbd65dd5b01cc959e3ccbc89330ddd0122296ea3
ToppCellsevere_influenza-Neutrophil|World / disease group, cell group and cell class (v2)

MAPK14 LRRK2 PYGL MME

2.99e-04174824f9f07436b7d3f190800cd85d229f007032f391e1
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TRPM3 LRRK2 ROS1 MME

2.99e-04174824b3cd22e717d178269e6d5bd5ed7b2d945cd8ea25
ToppCellfacs-Heart-LV-24m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

POSTN SAP25 EGFLAM ARHGEF17

2.99e-04174824a0a059bb2a64d7011e206db2ebcdf3eb655a925a
ToppCellAdult-Epithelial-lung_goblet_cell-D231|Adult / Lineage, Cell type, age group and donor

IGF2BP2 SERPINB11 PLCB4 TFAP2A

2.99e-041748247d2f802f493f19a068e097b2909a9000e2160266
ToppCellfacs-Heart-LV-24m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

POSTN SAP25 EGFLAM ARHGEF17

2.99e-041748247cd6f9103133f8d7b90f9ff4b3b0b078cf554542
ToppCellCOVID-19-kidney-REN+Pericyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

POSTN TRPM3 ATP11C ARHGEF17

2.99e-041748248393f0b43c767839c1630bcb952d62b42efc788d
ToppCellfacs-Lung-EPCAM-18m-Mesenchymal-Pericyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

POSTN EGFLAM GPRC6A ARHGEF17

3.05e-04175824d2ff8fedca9039cbd45cfd9dec88f4edbe7fe4fc
ToppCellfacs-Lung-3m-Mesenchymal-myofibroblast-pericyte_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

POSTN EGFLAM GPRC6A ARHGEF17

3.05e-041758242a53d4f140d5ab096efe8118d8aa351db7838b49
ToppCellfacs-Lung-EPCAM-18m-Mesenchymal-pericyte_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

POSTN EGFLAM GPRC6A ARHGEF17

3.05e-04175824a7310950e8d51b3004ea3aee8ce9948fe8655112
ToppCellfacs-Lung-3m-Mesenchymal-myofibroblast-pericyte_cell-pericyte|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

POSTN EGFLAM GPRC6A ARHGEF17

3.05e-04175824fb91a45763e4c48d993094a13088ffc19f1e2574
ToppCelldroplet-Lung-3m-Mesenchymal-myofibroblast-pericyte_cell-pericyte|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

POSTN EGFLAM GPRC6A ARHGEF17

3.12e-04176824e2b59a904c5c8f9c88e1e63788e9b6485f22edd0
ToppCelldroplet-Lung-3m-Mesenchymal-myofibroblast-pericyte_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

POSTN EGFLAM GPRC6A ARHGEF17

3.12e-04176824f931192e3cc65414e2245354f443473696cc7ce8
ToppCelldroplet-Lung-nan-3m-Mesenchymal-pericyte_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

POSTN EGFLAM GPRC6A ARHGEF17

3.19e-0417782465709bd546cb1ec6aa2ddd8b2adb46e174eb9a9a
ToppCelldroplet-Lung-nan-3m-Mesenchymal-Pericyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

POSTN EGFLAM GPRC6A ARHGEF17

3.19e-041778248684d47a547e2a06496f15e8da0200ecddc431e0
ToppCellfacs-Lung-18m-Mesenchymal-myofibroblast-pericyte_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

POSTN EGFLAM GPRC6A ARHGEF17

3.26e-041788248bae5db100f4563aa1fc7f881e7f8c59d669e37a
ToppCellPCW_05-06-Neuronal-Neuronal_postreplicative-neuro_migrating_neuronal_(3)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

POSTN TRPM3 PLCB4 TFAP2A

3.26e-0417882438ffbd01230c99f52274424ee6c172381daffc73
ToppCellfacs-Lung-18m-Mesenchymal-myofibroblast-pericyte_cell-pericyte|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

POSTN EGFLAM GPRC6A ARHGEF17

3.26e-04178824bc0336692b84bd0fa49747ed5a031b8ed8afa0fd
ToppCellCOVID-19_Mild-Hematopoietic_SC-HSPC|COVID-19_Mild / Disease group, lineage and cell class

IGF2BP2 PLCB4 PRKG2 ARHGEF17

3.33e-0417982419fcf48f5e02e4cb2b328efb4502f337e1282f72
ToppCellPBMC-Mild-Hematopoietic-HSPC-HSPC-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IGF2BP2 PLCB4 PRKG2 ARHGEF17

3.33e-041798244bb2debfc9e9f258cd38e797ef160bd440aad6af
ToppCell3'-Pediatric_IBD-SmallIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CES1 ROS1 FEV ITPRID2

3.33e-04179824f2e8fc975c30992611630197b79daaeef7c4211d
ToppCellfacs-Lung-nan-3m-Mesenchymal-Pericyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

POSTN EGFLAM GPRC6A ARHGEF17

3.33e-041798247078022e60faa86444f2a2c6eb9f767cc66b5cfa
ToppCellPBMC-Mild-Hematopoietic-HSPC|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IGF2BP2 PLCB4 PRKG2 ARHGEF17

3.33e-041798242f690f933bf6b99abeb31766e0b22bdbe36c1ba0
ToppCellPBMC-Mild-Hematopoietic-HSPC-HSPC|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IGF2BP2 PLCB4 PRKG2 ARHGEF17

3.33e-041798243e2c937369b8190fd5d5a31689d029e6e89fb5e2
ToppCellCOVID-19-Heart-EC_2|COVID-19 / Disease (COVID-19 only), tissue and cell type

ESR2 ENTPD1 FRYL PLCB4

3.33e-041798242a53d94f6c30bf887dfe88f1693ea057218c852d
ToppCellPND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

POSTN EGFLAM GPRC6A ARHGEF17

3.33e-0417982456db12467b445f2b8ef92af50779eeab10413eb2
ToppCellCOVID-19_Mild-Hematopoietic_SC|COVID-19_Mild / Disease group, lineage and cell class

IGF2BP2 PLCB4 PRKG2 ARHGEF17

3.33e-0417982450a073166e34bcfa52a62c4dafb3aef724e0fa8e
ToppCellfacs-Lung-nan-3m-Mesenchymal-pericyte_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

POSTN EGFLAM GPRC6A ARHGEF17

3.33e-04179824d4a975d8ffa5e77fb5c0ec05bf9c8f843c77ce07
ToppCellfacs-Lung-18m-Mesenchymal-myofibroblast|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

POSTN EGFLAM GPRC6A ARHGEF17

3.47e-04181824dff264815a3569f5666d0bbc3867c0496cd78774
ToppCellPBMC-Mild-Hematopoietic-HSPC-HSPC-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

IGF2BP2 PLCB4 PRKG2 ARHGEF17

3.47e-04181824e7f7b519c2a01c15f26df11ec9b434c0d1630c7a
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

IGF2BP2 TRPM3 PCDH15 MME

3.47e-041818249542c19edc9bd2cba68c01c2a8407705398e3011
ToppCellPBMC-Mild-Hematopoietic-HSPC-HSPC|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

IGF2BP2 PLCB4 PRKG2 ARHGEF17

3.47e-0418182454a19cf6a3b752e2391feb8b316bebee0e602d17
ToppCellPBMC-Mild-Hematopoietic-HSPC|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

IGF2BP2 PLCB4 PRKG2 ARHGEF17

3.47e-041818245b84625b1d3737708001b64f6da9360330d39a27
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

IGF2BP2 TRPM3 PCDH15 MME

3.47e-041818248f04f8cac5d705dc5f6cf6f4516d6e45b0aa4ae5
ToppCelldroplet-Lung-LUNG-1m-Mesenchymal-pericyte_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

POSTN EGFLAM GPRC6A ARHGEF17

3.54e-041828249edaccf1154cec92ca9a28e9b1f9075cfd422bfd
ToppCelldroplet-Lung-LUNG-1m-Mesenchymal-Pericyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

POSTN EGFLAM GPRC6A ARHGEF17

3.54e-04182824aba4c06d5d7618ac21b2695bca8e7a1346a91090
ToppCellPCW_05-06-Neuronal-Neuronal_SCP-neuro_proliferating_SCP2_(1)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

POSTN TRPM3 EGFLAM TFAP2A

3.54e-04182824f7f9be9c7ef8da9864d6aefe20043b26e1bb8697
ToppCellpdx-Tumor_cells-T6|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

TRPM3 EGFLAM PLCB4 MAML3

3.54e-041828247b24a4f712e1ae1525e8f1c8ec4e1fc43489cbee
ToppCellfacs-Pancreas-Endocrine-18m-Epithelial-pancreatic_A_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PYGL EGFLAM FEV KDM6B

3.54e-04182824f5f42e23832d0210560009ce6fd8eee89751e252
ToppCell3'-GW_trimst-1-LargeIntestine-Neuronal-Glial_immature-Glia_1_(DHH+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

POSTN TRPM3 EGFLAM TFAP2A

3.62e-04183824547b1fb9f9940cfc8d6e351d96acc0da44def57e
ToppCellPCW_05-06-Neuronal-Neuronal_SCP-neuro_SCP_(0)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

POSTN EGFLAM PLCB4 TFAP2A

3.62e-04183824f517215ff45dec914af52dfdbc4579c19654c3aa
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRANK1 TRPM3 PCDH15 ROS1

3.69e-041848242cbed6462fea2622871bb7e49b0df3d984239281
ToppCell3'-Broncho-tracheal-Epithelial-Neuro-endocrine/ionocytic-ionocyte-Ionocyte-Ionocyte_L.0.7.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

POSTN GPRC6A PLCB4 ITPRID2

3.69e-04184824a60802e11dcc5f932811260b08a95a32f60f6b19
ToppCell3'-Adult-SmallIntestine-Epithelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MTTP MME PRKG2 MUCL3

3.69e-04184824ed7a8e79e5723a5f5a03f542203d9e50bdef5f50
ToppCell3'-Broncho-tracheal-Epithelial-Neuro-endocrine/ionocytic-ionocyte|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

POSTN GPRC6A PLCB4 ITPRID2

3.69e-0418482439c230d32e4259bc784e0edfd9e2884c96898564
ToppCell3'-Broncho-tracheal-Epithelial-Neuro-endocrine/ionocytic-ionocyte-Ionocyte|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

POSTN GPRC6A PLCB4 ITPRID2

3.69e-041848242a2fb691cc9414ef5b06c26239d2da03d6d7e5c2
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRANK1 TRPM3 PCDH15 ROS1

3.69e-04184824ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRANK1 TRPM3 PCDH15 ROS1

3.69e-041848242b19a8c5f823e00812908b23e66bb4e563278aff
Diseaseresponse to selective serotonin reuptake inhibitor

CYP2A7 TSHZ3 TRPM3 EGFLAM

6.76e-0582784EFO_0005658
DiseaseCongenital small ears

POLR1D PLCB4 TFAP2A

1.76e-0441783C0152423
Diseaserectum cancer (is_implicated_in)

MAPK14 NBN

2.45e-049782DOID:1993 (is_implicated_in)
DiseaseMedulloblastoma

ESR2 BRD4 NBN

3.18e-0450783C0025149
DiseaseMalignant neoplasm of breast

ZNF438 BRIP1 ESR2 DDX18 UBR4 NLRC5 NBN MME TFAP2A HNRNPL

5.22e-0410747810C0006142
DiseaseHereditary Breast and Ovarian Cancer Syndrome

BRIP1 NBN

6.15e-0414782C0677776
Diseasebreast cancer (is_implicated_in)

BRIP1 ESR2 WRN NBN

6.83e-04150784DOID:1612 (is_implicated_in)
DiseaseParkinson's disease (is_implicated_in)

POLG ESR2 LRRK2

1.09e-0376783DOID:14330 (is_implicated_in)
DiseaseDown syndrome (is_marker_for)

BRIP1 GDI2

1.54e-0322782DOID:14250 (is_marker_for)
Diseaseovarian carcinoma

BRIP1 SERPINB11 TTLL10 GABBR2 TFAP2A

1.63e-03321785EFO_0001075
Diseasefemale reproductive system disease

GREB1 GABBR2

1.68e-0323782EFO_0009549
Diseasesmoking behavior

CYP2A7 IGF2BP2 DDX18 PCDH15 MAML3

2.12e-03341785EFO_0004318
DiseaseAdenocarcinoma of large intestine

TYK2 ROS1 PRKG2

2.13e-0396783C1319315
DiseaseAutosomal Dominant Parkinsonism

POLG LRRK2

2.49e-0328782C0752098
DiseaseAutosomal Dominant Juvenile Parkinson Disease

POLG LRRK2

2.49e-0328782C0752097
DiseaseParkinsonism, Experimental

POLG LRRK2

2.49e-0328782C0752101
DiseaseAutosomal Recessive Parkinsonism

POLG LRRK2

2.49e-0328782C0752100
DiseaseFamilial Juvenile Parkinsonism

POLG LRRK2

2.49e-0328782C0752104
Diseaseosteoarthritis (is_implicated_in)

NCOR2 ESR2

2.49e-0328782DOID:8398 (is_implicated_in)
DiseaseRamsay Hunt Paralysis Syndrome

POLG LRRK2

2.49e-0328782C0242423
DiseasePARKINSON DISEASE 2, AUTOSOMAL RECESSIVE JUVENILE

POLG LRRK2

2.49e-0328782C1868675

Protein segments in the cluster

PeptideGeneStartEntry
MQLMSYPLSEGQLDQ

CES1

361

P23141
SPGMMRQLNINGALY

EGFLAM

951

Q63HQ2
PPLTSMQMQLYLQQL

BRD4

921

O60885
MRQSGASQPLLINMY

FEV

1

Q99581
LKAMDKMYLSNNPNS

TFAP2A

406

P05549
QSCLQMGMYLNQLLS

ASTE1

546

Q2TB18
NPANMSKYQSNPKVM

ST13P5

341

Q8NFI4
NPANMSKYQSNPKVM

ST13

341

P50502
MMSKPQTSGAYVLNK

RBM27

731

Q9P2N5
QIKPYTLMSMVANLL

PSMB3

81

P49720
RTLMQGYMQPLKQPE

ARHGEF17

1086

Q96PE2
IINMLLSPSAKMQYV

ANKAR

996

Q7Z5J8
YNPLIMRLQAGVMAS

NCOR2

2461

Q9Y618
YVPKMLTNLMNQEST

OR2A14

76

Q96R47
LMANGQLVKMLLYTE

GDI2

81

P50395
KAMILLNSSMYPLVT

ESR2

401

Q92731
PMANNLQKTTMNNYL

MAML3

556

Q96JK9
LMAVSGLPQMKNYTS

GREB1

911

Q4ZG55
RNYIQSLTQMPKMNF

MAPK14

256

Q16539
LTAFLMMGNLSPNLK

FAM91A1

386

Q658Y4
LGMNTVQLYMKVPGS

KDM6B

1371

O15054
KMKMAGLNAIQTYVP

GLB1

71

P16278
LLSIGELPQEMNKYM

MTTP

561

P55157
RMVQSYQLLAQAKPM

FRYL

2991

O94915
YQLLAQAKPMGNMVS

FRYL

2996

O94915
PMLLYNKMTLAQIQN

MME

296

P08473
GMLEMGVSYLPVNQN

POLG

426

P54098
PYNRMKLMIVGNTGS

LRRK2

1331

Q5S007
MMNKLYIGNLSPAVT

IGF2BP2

1

Q9Y6M1
MQNTPGFMYKNLQCL

DDX18

316

Q9NVP1
TLGYMLNLTNMIPAE

ENTPD1

451

P49961
LGNSTVIAPKMLMNF

OR8J3

71

Q8NGG0
RNSLQNLSQYPMMRG

ITPRID2

921

P28290
SGVDQMMTYNLILKG

PRKG2

651

Q13237
GQSVALLPNMTQLYM

NLRC5

426

Q86WI3
SYASNNVPKMLANLM

OR2A2

71

Q6IF42
AYPSQLAMMNSILRG

BRIP1

21

Q9BX63
SRMLNLQLMPQVGYE

GPRC6A

156

Q5T6X5
PLLYPVMMSNKLSAQ

OR5AC2

131

Q9NZP5
VPQMMNPFIYSLRNK

OR7G1

281

Q8NGA0
MTSMYGHLLGLQKLN

PLA2G4E

386

Q3MJ16
LMDPVKQMLFLNSTG

PCDH15

86

Q96QU1
NAGILKMNMGNIYLK

IFT88

231

Q13099
MLRTNQPYTGPMLNN

BICRAL

451

Q6AI39
KQQSMMFRPLSQSLY

MT-CYB

311

P00156
NPNTEFYLKNLMMST

CYP2A7

281

P20853
MYQTMKILNLGNEGN

HEATR4

851

Q86WZ0
SPVLMVYGLDQSKMN

HNRNPL

381

P14866
NRNQKLIKMSSPYMN

GABBR2

506

O75899
LIKMSSPYMNNLIIL

GABBR2

511

O75899
SPYMNNLIILGGMLS

GABBR2

516

O75899
LYGDQMLTLQVGNMT

KLF18

891

A0A0U1RQI7
LMANGQLVKMLLYTE

GDI1

81

P31150
YLMEQQNLGMGQIPS

MUCL3

501

Q3MIW9
TPQDLSMAMQKIYQT

NUP58

381

Q9BVL2
MAVLPYNPNMTILNL

MT-ND2

191

P03891
LGNSLRYMIMKNPEV

POLR1D

51

P0DPB6
LAGNLLVLYLMKSMQ

RXFP3

96

Q9NSD7
PLYLSKAPQQMMGSL

SAP25

96

Q8TEE9
NRLLYNKQKMNTDPM

SUPT20HL1

221

Q3ZLR7
MVSLNYQTPDLAMQL

PLCB4

646

Q15147
VRQQLLQGYDMLMNP

NDUFAF7

381

Q7L592
MVSNTLAKMRIPNYQ

NBN

416

O60934
AMCQVKNQPLVYLML

SEC24A

926

O95486
LGMAYISSQMGPVLQ

SLC5A6

411

Q9Y289
SMSVFPQGLKMLLEN

WRN

116

Q14191
MQVLELPYVNNKLSM

SERPINB11

231

Q96P15
YMAQLMKNTGVILAN

NOP2

401

P46087
IQLTMLGAMQVSKYG

OXCT2

391

Q9BYC2
NRLLYNKQKMNTDPM

SUPT20HL2

221

P0C7V6
DPRLYMKISGNAMLQ

ATP11C

941

Q8NB49
LQLIQSYQRMPGNAM

SENP3

361

Q9H4L4
PYQTMSNPMSKLTVL

TRPM3

271

Q9HCF6
PVQSGMYKLNNMLSL

FGD6

1121

Q6ZV73
IKRGSMYMQQQQPLL

TOMM70

371

O94826
GTMLNVPELQSAMKY

ROS1

631

P08922
QLLMNNPYLAAQIML

UBQLNL

431

Q8IYU4
NVMMKNNKLAVSPNY

ZNF518A

426

Q6AHZ1
HAAYQLPNMMKLSLG

TSHZ3

551

Q63HK5
LENIYSMMLTLIGQK

XPNPEP3

381

Q9NQH7
IGMLNNPMNAVTTKF

WDR33

96

Q9C0J8
SQGRSLMVNPEMYKL

TRANK1

1621

O15050
NGMIIPSMYNNLGLF

POSTN

181

Q15063
SKTYINQLSMNSPEM

UBR4

1016

Q5T4S7
YMGRTLQNTMINLGL

PYGL

91

P06737
LDMKLYMSQTNSGPL

USP17L15

301

C9J2P7
HLTNQFMQKKSPLYM

TTLL10

416

Q6ZVT0
KLLGMSTQNYALMQV

ZNF438

71

Q7Z4V0
QPGRLSQQMVMVKYL

TYK2

246

P29597