Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiontransferase activity, transferring phosphorus-containing groups

CSNK1D CSNK1E GRK7 PI4KA POLI DGKB DGKG DCK TTK FGGY POLR3A EPHA3 MAP3K2 EPHA4

1.21e-049389414GO:0016772
GeneOntologyMolecularFunctionphosphotransferase activity, alcohol group as acceptor

CSNK1D CSNK1E GRK7 PI4KA DGKB DGKG DCK TTK FGGY EPHA3 MAP3K2 EPHA4

1.22e-047099412GO:0016773
GeneOntologyMolecularFunctioncollagen binding involved in cell-matrix adhesion

ITGA1 ITGA2

2.17e-045942GO:0098639
GeneOntologyMolecularFunctionkinase activity

CSNK1D CSNK1E GRK7 PI4KA DGKB DGKG DCK TTK FGGY EPHA3 MAP3K2 EPHA4

2.43e-047649412GO:0016301
GeneOntologyMolecularFunctionGPI-linked ephrin receptor activity

EPHA3 EPHA4

4.53e-047942GO:0005004
GeneOntologyBiologicalProcessfasciculation of motor neuron axon

EPHA3 EPHA4

1.93e-052912GO:0097156
DomainDAG_kinase_N

DGKB DGKG

7.65e-053952PF14513
DomainElf-1_N

ELF1 ELF2

7.65e-053952PF12310
DomainDAG_kinase_typeI_N

DGKB DGKG

7.65e-053952IPR029477
Domain-

DGKB DGKG

7.65e-0539521.10.238.110
DomainTF_Elf_N

ELF1 ELF2

7.65e-053952IPR022084
DomainVDCC_L_bsu

CACNB1 CACNB4

1.53e-044952IPR000584
DomainVGCC_beta4Aa_N

CACNB1 CACNB4

1.53e-044952PF12052
Domain-

C19orf47 KAZN EPHA3 EPHA4 L3MBTL4

2.07e-041069551.10.150.50
DomainSAM/pointed

C19orf47 KAZN EPHA3 EPHA4 L3MBTL4

3.27e-04117955IPR013761
DomainQuin_OxRdtase/zeta-crystal_CS

PTGR3 VAT1

5.29e-047952IPR002364
DomainQOR_ZETA_CRYSTAL

PTGR3 VAT1

5.29e-047952PS01162
DomainVWFA

INTS6L COL6A6 ITGA1 ITGA2

8.11e-0482954PS50234
DomainVWA

INTS6L COL6A6 ITGA1 ITGA2

8.88e-0484954SM00327
DomainSAM

KAZN EPHA3 EPHA4 L3MBTL4

1.06e-0388954SM00454
DomainDAGK_acc

DGKB DGKG

1.12e-0310952PF00609
DomainDiacylglycerol_kin_accessory

DGKB DGKG

1.12e-0310952IPR000756
DomainDAGKa

DGKB DGKG

1.12e-0310952SM00045
DomainSAM_2

KAZN EPHA3 EPHA4

1.36e-0343953PF07647
DomainSAM_DOMAIN

KAZN EPHA3 EPHA4 L3MBTL4

1.40e-0395954PS50105
DomainSAM

KAZN EPHA3 EPHA4 L3MBTL4

1.52e-0397954IPR001660
DomainVWF_A

INTS6L COL6A6 ITGA1 ITGA2

1.63e-0399954IPR002035
DomainRECEPTOR_TYR_KIN_V_2

EPHA3 EPHA4

2.24e-0314952PS00791
DomainRECEPTOR_TYR_KIN_V_1

EPHA3 EPHA4

2.24e-0314952PS00790
DomainEph_TM

EPHA3 EPHA4

2.24e-0314952IPR027936
DomainTyr_kinase_rcpt_V_CS

EPHA3 EPHA4

2.24e-0314952IPR001426
DomainEPH_lbd

EPHA3 EPHA4

2.24e-0314952SM00615
DomainEphrin_lbd

EPHA3 EPHA4

2.24e-0314952PF01404
DomainEphA2_TM

EPHA3 EPHA4

2.24e-0314952PF14575
DomainTyr_kinase_ephrin_rcpt

EPHA3 EPHA4

2.24e-0314952IPR016257
DomainEphrin_rcpt_lig-bd_dom

EPHA3 EPHA4

2.24e-0314952IPR001090
DomainEPH_LBD

EPHA3 EPHA4

2.24e-0314952PS51550
DomainDAGKc

DGKB DGKG

2.24e-0314952SM00046
DomainDiacylglycerol_kinase_cat_dom

DGKB DGKG

2.57e-0315952IPR001206
DomainDAGK_cat

DGKB DGKG

2.57e-0315952PF00781
DomainDAGK

DGKB DGKG

2.57e-0315952PS50146
DomainVWA

COL6A6 ITGA1 ITGA2

2.91e-0356953PF00092
DomainADH_N

PTGR3 VAT1

2.93e-0316952PF08240
DomainIntegrin_alpha_C_CS

ITGA1 ITGA2

2.93e-0316952IPR018184
DomainPKS_ER

PTGR3 VAT1

2.93e-0316952SM00829
DomainPKS_ER

PTGR3 VAT1

2.93e-0316952IPR020843
DomainADH_N

PTGR3 VAT1

2.93e-0316952IPR013154
DomainProtein_kinase_ATP_BS

CSNK1D CSNK1E GRK7 TTK EPHA3 MAP3K2 EPHA4

3.21e-03379957IPR017441
DomainNAD/diacylglycerol_kinase

DGKB DGKG

3.31e-0317952IPR016064
DomainIntegrin_alpha-2

ITGA1 ITGA2

3.71e-0318952IPR013649
DomainIntegrin_alpha2

ITGA1 ITGA2

3.71e-0318952PF08441
Domain-

PTGR3 VAT1

3.71e-03189523.90.180.10
DomainIntegrin_alpha

ITGA1 ITGA2

3.71e-0318952IPR000413
DomainINTEGRIN_ALPHA

ITGA1 ITGA2

3.71e-0318952PS00242
DomainDH_1

ARHGEF40 ARHGEF38 ECT2

4.06e-0363953PS00741
DomainInt_alpha_beta-p

ITGA1 ITGA2

4.14e-0319952IPR013519
DomainADH_zinc_N

PTGR3 VAT1

4.14e-0319952PF00107
DomainADH_SF_Zn-type

PTGR3 VAT1

4.14e-0319952IPR002085
DomainInt_alpha

ITGA1 ITGA2

4.14e-0319952SM00191
DomainADH_C

PTGR3 VAT1

4.14e-0319952IPR013149
DomainSH3

FNBP1 CACNB1 CACNB4 ARHGEF38 NEB

4.93e-03216955SM00326
DomainSH3

FNBP1 CACNB1 CACNB4 ARHGEF38 NEB

4.93e-03216955PS50002
PathwayREACTOME_NERVOUS_SYSTEM_DEVELOPMENT

CACNB1 CACNB4 AP2M1 MYL9 COL6A6 RNPS1 SCN4A RPS15 PSMC4 ITGA1 ITGA2 EPHA3 EPHA4

6.86e-065757313M29853
Pubmed

Collagen XVI harbors an integrin alpha1 beta1 recognition site in its C-terminal domains.

COL16A1 ITGA1 ITGA2

7.88e-08495316754661
Pubmed

A High-Density Human Mitochondrial Proximity Interaction Network.

RAB10 CSNK1D CSNK1E PI4KA PSMC4 ANKMY2 VTA1 ZDBF2 EMC8 OGDH TTK DDB1 TTC19 HNRNPL POLR3A VAT1 ALG13

5.75e-071496951732877691
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

ARHGEF40 AP2M1 RNPS1 PI4KA RPS15 PSMC4 VTA1 DCK FHL2 ECT2 DDB1 G6PD CPSF3 NT5DC1 HNRNPL POLR3A

7.68e-071353951629467282
Pubmed

BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.

RAB10 AP2M1 PBRM1 RNPS1 RBBP6 C19orf47 RPS15 PSMC4 CHD6 DCK TTK CPSF3 SNX2 PTGR3 HNRNPL

2.83e-061318951530463901
Pubmed

Large-scale proteomics and phosphoproteomics of urinary exosomes.

RAB10 AP2M1 CETP PDZK1 ABCB11 VTA1 IRF6 ITGA1 NEB DDB1 G6PD HNRNPL VAT1

3.99e-061016951319056867
Pubmed

Quantitative trait loci affecting the 3D skull shape and size in mouse and prioritization of candidate genes in-silico.

SOX9 COL16A1 ITGA2 EPHA3

3.99e-063995425859222
Pubmed

A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.

CACNB1 AP2M1 RNPS1 CHD6 KAZN FHL2 GDI1 CYB5R2 TTC19 ALG13

6.60e-06608951016713569
Pubmed

The KMT2D Kabuki syndrome histone methylase controls neural crest cell differentiation and facial morphology.

SOX9 COL16A1 PCOLCE

7.03e-061495332541010
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

AP2M1 PBRM1 RNPS1 CSNK1E PI4KA PSMC4 EMC8 OGDH DDB1 G6PD CPSF3 SNX2 HNRNPL POLR3A VAT1

7.26e-061425951530948266
Pubmed

Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.

RAB10 AP2M1 RNPS1 RBBP6 CSNK1D CSNK1E ASCC1 RPS15 PSMC4 FHL2 GDI1 DDB1 G6PD HNRNPL

7.35e-061247951427684187
Pubmed

Casein kinase 1delta activates human recombinant deoxycytidine kinase by Ser-74 phosphorylation, but is not involved in the in vivo regulation of its activity.

CSNK1D DCK

7.38e-06295220637175
Pubmed

Casein kinase I delta/epsilon phosphorylates topoisomerase IIalpha at serine-1106 and modulates DNA cleavage activity.

CSNK1D CSNK1E

7.38e-06295219043076
Pubmed

CK1δ and CK1ε are components of human 40S subunit precursors required for cytoplasmic 40S maturation.

CSNK1D CSNK1E

7.38e-06295224424021
Pubmed

SOX9 Promotes Collagen VI Secretion by Upregulating PCOLCE in Neurofibroma.

SOX9 PCOLCE

7.38e-06295238436832
Pubmed

TNF-α promotes cerebral pericyte remodeling in vitro, via a switch from α1 to α2 integrins.

ITGA1 ITGA2

7.38e-06295223448258
Pubmed

The effects of inhibition and siRNA knockdown of collagen-binding integrins on human umbilical vein endothelial cell migration and tube formation.

ITGA1 ITGA2

7.38e-06295236517525
Pubmed

Collagen receptors α(1)β(1) and α(2)β(1) integrins are involved in transmigration of peripheral blood eosinophils, but not mononuclear cells through human microvascular endothelial cells monolayer.

ITGA1 ITGA2

7.38e-06295223070086
Pubmed

The human formin-binding protein 17 (FBP17) interacts with sorting nexin, SNX2, and is an MLL-fusion partner in acute myelogeneous leukemia.

FNBP1 SNX2

7.38e-06295211438682
Pubmed

[Study of C807T polymorphism of the platelet collagen receptor alpha2 gene coding sequence in Suzhou Han population].

ITGA1 ITGA2

7.38e-06295211877061
Pubmed

Regulation of casein kinase I epsilon and casein kinase I delta by an in vivo futile phosphorylation cycle.

CSNK1D CSNK1E

7.38e-0629529632646
Pubmed

Influence of collagen-based integrin α1 and α2 mediated signaling on human mesenchymal stem cell osteogenesis in three dimensional contexts.

ITGA1 ITGA2

7.38e-06295229761640
Pubmed

Segregation of axial motor and sensory pathways via heterotypic trans-axonal signaling.

EPHA3 EPHA4

7.38e-06295218403711
Pubmed

Structures of the murine genes for the beta1- and beta4-subunits of the voltage-dependent calcium channel.

CACNB1 CACNB4

7.38e-06295214500989
Pubmed

Effects of altered expression and activity levels of CK1δ and ɛ on tumor growth and survival of colorectal cancer patients.

CSNK1D CSNK1E

7.38e-06295225404202
Pubmed

Characterization of NERF, a novel transcription factor related to the Ets factor ELF-1.

ELF1 ELF2

7.38e-0629528756667
Pubmed

Androgens and integrins in salivary glands in Sjogren's syndrome.

ITGA1 ITGA2

7.38e-06295220436081
Pubmed

An evaluation of polymorphisms in casein kinase 1 delta and epsilon genes in major psychiatric disorders.

CSNK1D CSNK1E

7.38e-06295222981886
Pubmed

Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.

RAB10 AP2M1 RPS15 PSMC4 OGDH DDB1 G6PD TMEM200A HNRNPL VAT1 ALG13

1.30e-05807951130575818
Pubmed

Sall genes regulate region-specific morphogenesis in the mouse limb by modulating Hox activities.

SOX9 EPHA3 EPHA4

1.31e-051795319168674
Pubmed

Type IV collagen drives alveolar epithelial-endothelial association and the morphogenetic movements of septation.

SOX9 ITGA1 ITGA2

1.56e-051895327412481
Pubmed

Upregulation of RIN3 induces endosomal dysfunction in Alzheimer's disease.

FNBP1 RAB10 RNPS1 PSMC4 DDB1 HNRNPL CCNA2 VAT1

1.99e-0541895832552912
Pubmed

Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.

RAB10 NLN AP2M1 RPS15 PSMC4 DCK FHL2 OGDH GDI1 DDB1 G6PD CPSF3 HNRNPL VAT1

2.05e-051367951432687490
Pubmed

Targeting of the circadian clock via CK1δ/ε to improve glucose homeostasis in obesity.

CSNK1D CSNK1E

2.21e-05395227439882
Pubmed

Expression and functional importance of collagen-binding integrins, alpha 1 beta 1 and alpha 2 beta 1, on virus-activated T cells.

ITGA1 ITGA2

2.21e-05395212960301
Pubmed

CKIepsilon/delta-dependent phosphorylation is a temperature-insensitive, period-determining process in the mammalian circadian clock.

CSNK1D CSNK1E

2.21e-05395219805222
Pubmed

Determination of the ligand-binding specificities of the alpha2beta1 and alpha1beta1 integrins in a novel 3-dimensional in vitro model of pancreatic cancer.

ITGA1 ITGA2

2.21e-05395217312461
Pubmed

Centrosomal anchoring of the protein kinase CK1delta mediated by attachment to the large, coiled-coil scaffolding protein CG-NAP/AKAP450.

CSNK1D CSNK1E

2.21e-05395212270714
Pubmed

The formin-binding protein 17, FBP17, binds via a TNKS binding motif to tankyrase, a protein involved in telomere maintenance.

FNBP1 SNX2

2.21e-05395214596906
Pubmed

Casein kinase 1 proteomics reveal prohibitin 2 function in molecular clock.

CSNK1D CSNK1E

2.21e-05395222384121
Pubmed

Identification and cloning of ELF-1, a developmentally expressed ligand for the Mek4 and Sek receptor tyrosine kinases.

EPHA3 EPHA4

2.21e-0539527522971
Pubmed

Transcriptional and epigenetic regulation of the integrin collagen receptor locus ITGA1-PELO-ITGA2.

ITGA1 ITGA2

2.21e-05395217669516
Pubmed

hnRNP L regulates differences in expression of mouse integrin alpha2beta1.

ITGA2 HNRNPL

2.21e-05395216455949
Pubmed

Gene expression levels of Casein kinase 1 (CK1) isoforms are correlated to adiponectin levels in adipose tissue of morbid obese patients and site-specific phosphorylation mediated by CK1 influences multimerization of adiponectin.

CSNK1D CSNK1E

2.21e-05395225724478
Pubmed

Mass-spectrometry-based proteomic correlates of grade and stage reveal pathways and kinases associated with aggressive human cancers.

TTK MAP3K2

2.21e-05395233627787
Pubmed

A comparative study of structural and conformational properties of casein kinase-1 isoforms: insights from molecular dynamics and principal component analysis.

CSNK1D CSNK1E

2.21e-05395225665722
Pubmed

Type VIII collagen stimulates smooth muscle cell migration and matrix metalloproteinase synthesis after arterial injury.

ITGA1 ITGA2

2.21e-05395210666376
Pubmed

Vascular collagens: spotlight on the role of type VIII collagen in atherogenesis.

ITGA1 ITGA2

2.21e-05395212482545
Pubmed

CRISPR-mediated gene targeting of CK1δ/ε leads to enhanced understanding of their role in endocytosis via phosphoregulation of GAPVD1.

CSNK1D CSNK1E

2.21e-05395232321936
Pubmed

Vimocin and vidapin, cyclic KTS peptides, are dual antagonists of α1β1/α2β1 integrins with antiangiogenic activity.

ITGA1 ITGA2

2.21e-05395224939421
Pubmed

Suppression of KSHV lytic replication and primary effusion lymphoma by selective RNF5 inhibition.

EPHA3 EPHA4

2.21e-05395236656913
Pubmed

Casein kinase 1-epsilon or 1-delta required for Wnt-mediated intestinal stem cell maintenance.

CSNK1D CSNK1E

2.21e-05395228963394
Pubmed

Expression of beta 1 integrins in human dental pulp in vivo: a comparative immunohistochemical study on healthy and chronic marginal periodontitis samples.

ITGA1 ITGA2

2.21e-05395211307375
Pubmed

Human Rad17 C-terminal tail is phosphorylated by concerted action of CK1δ/ε and CK2 to promote interaction with the 9-1-1 complex.

CSNK1D CSNK1E

2.21e-05395231353086
Pubmed

The crucial role of collagen-binding integrins in maintaining the mechanical properties of human scleral fibroblasts-seeded collagen matrix.

ITGA1 ITGA2

2.21e-05395221647271
Pubmed

Sequence analysis of the cDNA for the human casein kinase I delta (CSNK1D) gene and its chromosomal localization.

CSNK1D CSNK1E

2.21e-0539528786104
Pubmed

Integrin α1/β1 and α2/β1 as a receptor for IgA1 in human glomerular mesangial cells in IgA nephropathy.

ITGA1 ITGA2

2.21e-05395222298882
Pubmed

alpha11beta1 integrin is a receptor for interstitial collagens involved in cell migration and collagen reorganization on mesenchymal nonmuscle cells.

ITGA1 ITGA2

2.21e-05395211518510
Pubmed

Integrins alpha1beta1 and alpha2beta1 are receptors for the rotavirus enterotoxin.

ITGA1 ITGA2

2.21e-05395218587047
Pubmed

Regional expression and subcellular localization of the voltage-gated calcium channel β subunits in the developing mouse brain.

CACNB1 CACNB4

2.21e-05395222737983
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

CSNK1D CSNK1E GRK7 SYDE2 PI4KA C19orf47 BRD1 ECT2 TTK SNX2 MAP3K2

2.37e-05861951136931259
Pubmed

The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.

AP2M1 COL16A1 PI4KA PDZK1 ATP13A3 ITGA2 EPHA3 EPHA4 VAT1

2.66e-0556995930639242
Pubmed

Overlapping Activities of Two Neuronal Splicing Factors Switch the GABA Effect from Excitatory to Inhibitory by Regulating REST.

CACNB4 ENPP2 SCG3 OGDH SNX2

2.77e-0512895530995482
Pubmed

Human transcription factor protein interaction networks.

SOX9 AP2M1 PBRM1 RBBP6 RPS15 ZBTB40 PSMC4 KLF3 ELF1 ELF2 CHD6 DDB1 HNRNPL CCNA2

3.33e-051429951435140242
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

EFCAB5 RAB10 AP2M1 GPR19 RNPS1 SCG3 SCN4A CHD6 EMC8 NEB OGDH CFAP69 EPHA4 VAT1

3.68e-051442951435575683
Pubmed

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.

ARHGEF40 AP2M1 MYL9 CSNK1D CSNK1E DCK TTK G6PD MAP3K2 CCNA2 EPHA4

3.91e-05910951136736316
Pubmed

Disruption and sequence identification of 2,000 genes in mouse embryonic stem cells.

SCG3 IRF6 CPSF3

4.35e-05259539560157
Pubmed

CK1δ/ε protein kinase primes the PER2 circadian phosphoswitch.

CSNK1D CSNK1E

4.41e-05495229784789
Pubmed

The laminin alpha2-chain short arm mediates cell adhesion through both the alpha1beta1 and alpha2beta1 integrins.

ITGA1 ITGA2

4.41e-0549529361014
Pubmed

EphA3 null mutants do not demonstrate motor axon guidance defects.

EPHA3 EPHA4

4.41e-05495214585969
Pubmed

Involvement of casein kinase 1 epsilon/delta (Csnk1e/d) in the pathogenesis of familial Parkinson's disease caused by CHCHD2.

CSNK1D CSNK1E

4.41e-05495237578019
Pubmed

The light peak of the electroretinogram is dependent on voltage-gated calcium channels and antagonized by bestrophin (best-1).

CACNB1 CACNB4

4.41e-05495216636205
Pubmed

A novel binding site in collagen type III for integrins alpha1beta1 and alpha2beta1.

ITGA1 ITGA2

4.41e-05495216043429
Pubmed

Casein kinase 1 delta functions at the centrosome to mediate Wnt-3a-dependent neurite outgrowth.

CSNK1D CSNK1E

4.41e-05495221422228
Pubmed

Discoidin domain receptors promote α1β1- and α2β1-integrin mediated cell adhesion to collagen by enhancing integrin activation.

ITGA1 ITGA2

4.41e-05495223284937
Pubmed

The DNA-binding activity of mouse DNA methyltransferase 1 is regulated by phosphorylation with casein kinase 1delta/epsilon.

CSNK1D CSNK1E

4.41e-05495220192920
Pubmed

VEGF-A promotes tissue repair-associated lymphatic vessel formation via VEGFR-2 and the alpha1beta1 and alpha2beta1 integrins.

ITGA1 ITGA2

4.41e-05495215132990
Pubmed

Therapeutic Targeting of Casein Kinase 1δ/ε in an Alzheimer's Disease Mouse Model.

CSNK1D CSNK1E

4.41e-05495231334659
Pubmed

Deletion of integrin alpha 1 by homologous recombination permits normal murine development but gives rise to a specific deficit in cell adhesion.

ITGA1 ITGA2

4.41e-0549528626034
Pubmed

p53 is phosphorylated in vitro and in vivo by the delta and epsilon isoforms of casein kinase 1 and enhances the level of casein kinase 1 delta in response to topoisomerase-directed drugs.

CSNK1D CSNK1E

4.41e-0549529349507
Pubmed

Isolation and characterization of human casein kinase I epsilon (CKI), a novel member of the CKI gene family.

CSNK1D CSNK1E

4.41e-0549527797465
Pubmed

Casein kinase 1 delta (CK1delta) regulates period length of the mouse suprachiasmatic circadian clock in vitro.

CSNK1D CSNK1E

4.41e-05495220421981
Pubmed

Ephrins guide migrating cortical interneurons in the basal telencephalon.

EPHA3 EPHA4

4.41e-05495220473036
Pubmed

Close homolog of L1 is an enhancer of integrin-mediated cell migration.

ITGA1 ITGA2

4.41e-05495212721290
Pubmed

The mapping of the gene of susceptibility to catalepsy in mice using polymorphic microsatellite markers.

ITGA1 ITGA2

4.41e-05495214994542
Pubmed

Mutations of calcium channel beta subunit genes in mice.

CACNB1 CACNB4

4.41e-05495210494839
Pubmed

Involvement of casein kinase Iepsilon in cytokine-induced granulocytic differentiation.

CSNK1D CSNK1E

4.41e-05495215070676
Pubmed

Reciprocal interactions regulate targeting of calcium channel beta subunits and membrane expression of alpha1 subunits in cultured hippocampal neurons.

CACNB1 CACNB4

4.41e-05495219996312
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

SOX9 PBRM1 RNPS1 ZBTB40 ELF1 ELF2 CHD6 BRD1 DDB1

4.45e-0560895936089195
Pubmed

Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.

RGL1 CACNB1 CPAMD8 CACNB4 KLHL10 TCP11L1 ATP13A3 EMC8 ITGA2 NEB FHL2 CCNA2 ALG13

5.03e-051293951315342556
Pubmed

Proteomics analysis of protein kinases by target class-selective prefractionation and tandem mass spectrometry.

CSNK1D CSNK1E EPHA3 MAP3K2

6.38e-057895417192257
Pubmed

WW domains provide a platform for the assembly of multiprotein networks.

RNPS1 DDB1 CPSF3 HNRNPL POLR3A

6.70e-0515495516055720
Pubmed

Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.

RAB10 PBRM1 RNPS1 PI4KA ELF2 CHD6 BRD1 CPSF3 CCNA2

6.99e-0564595925281560
Pubmed

Tumor suppressor BAP1 nuclear import is governed by transportin-1.

RAB10 AP2M1 TCP11L1 RPS15 PSMC4 VTA1 GDI1 DDB1 G6PD SNX2 HNRNPL VAT1

7.00e-051149951235446349
Pubmed

EZH2 interacts with HP1BP3 to epigenetically activate WNT7B that promotes temozolomide resistance in glioblastoma.

RAB10 AP2M1 RNPS1 RPS15 DGKG GDI1 G6PD HNRNPL MAP3K2 VAT1

7.03e-05803951036517590
Pubmed

A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.

AP2M1 CSNK1D CSNK1E RPS15 PSMC4 ANKMY2 FHL2 DDB1 G6PD SNX2 HNRNPL

7.19e-05974951128675297
Pubmed

Cholesteryl ester transfer protein (CETP) expression enhances HDL cholesteryl ester liver delivery, which is independent of scavenger receptor BI, LDL receptor related protein and possibly LDL receptor.

CETP PDZK1

7.34e-05595217055779
Pubmed

The N-terminal globular domain of the laminin alpha1 chain binds to alpha1beta1 and alpha2beta1 integrins and to the heparan sulfate-containing domains of perlecan.

ITGA1 ITGA2

7.34e-0559529688542
Pubmed

Phosphorylation of human enhancer filamentation 1 (HEF1) stimulates interaction with Polo-like kinase 1 leading to HEF1 localization to focal adhesions.

CSNK1D CSNK1E

7.34e-05595229191835
Pubmed

Predictive role of multilocus genetic polymorphisms in cardiovascular disease and inflammation-related genes on chronic kidney disease in Type 2 diabetes--an 8-year prospective cohort analysis of 1163 patients.

CETP ITGA2

7.34e-05595221765051
Pubmed

Diversity and developmental expression of L-type calcium channel beta2 proteins and their influence on calcium current in murine heart.

CACNB1 CACNB4

7.34e-05595219723630
GeneFamilySterile alpha motif domain containing

KAZN EPHA3 EPHA4 L3MBTL4

2.36e-0488624760
GeneFamilyEF-hand domain containing|Diacylglycerol kinases

DGKB DGKG

5.12e-04106221178
GeneFamilyFibronectin type III domain containing|Sterile alpha motif domain containing|EPH receptors

EPHA3 EPHA4

1.03e-03146221095
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

ARHGEF40 ARHGEF38 ECT2

1.51e-0366623722
GeneFamilyCD molecules|Integrin alpha subunits

ITGA1 ITGA2

1.71e-03186221160
GeneFamilyCalcium voltage-gated channel subunits

CACNB1 CACNB4

3.57e-0326622253
GeneFamilyCalcium voltage-gated channel subunits|Membrane associated guanylate kinases

CACNB1 CACNB4

3.57e-0326622904
GeneFamilyETS transcription factor family

ELF1 ELF2

4.13e-0328622534
GeneFamilyEF-hand domain containing

EFCAB5 MYL9 DGKB DGKG

6.75e-03219624863
GeneFamilyCollagens

COL16A1 COL6A6

1.09e-0246622490
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Mesenchymal-brain_pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

INTS6L MYL9 DGKB DGKG HTRA4 PCOLCE

1.94e-061739562415b6ff49f334da570577d4e93484d024a3dbd5
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Mesenchymal-Pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

INTS6L MYL9 DGKB DGKG HTRA4 PCOLCE

1.94e-061739562acd0693a2dfe04e3c1b2125ea63efe92d13150b
ToppCellPND01-03-samps-Mesenchymal-Myofibroblast|PND01-03-samps / Age Group, Lineage, Cell class and subclass

COL16A1 MYL9 ENPP2 CPXM1 FHL2 PCOLCE

2.60e-06182956812dac35b9aa05be48258082e007f6c00e7b4dd8
ToppCellfacs-Kidney-nan-3m-Mesenchymal-mesangial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYL9 COL6A6 SCG3 CPXM1 HTRA4 FHL2

3.23e-06189956a5306561026e4dfcc39beeb785e5108ac595d136
ToppCellfacs-Kidney-nan-3m-Mesenchymal|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYL9 COL6A6 SCG3 CPXM1 HTRA4 FHL2

3.23e-06189956381058f55908f84375b54601d617389ef43ab855
ToppCellfacs-Kidney-nan-3m-Mesenchymal-mesangial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYL9 COL6A6 SCG3 CPXM1 HTRA4 FHL2

3.23e-06189956302b950a6ad578f8aeff7ea6fd15fe631225287d
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL16A1 MYL9 CPXM1 ITGA1 FHL2 PCOLCE

3.65e-06193956dc8e62df6121ee99b156aca6b1b3ae555739b6f2
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

COL16A1 COL6A6 CPXM1 KAZN EPHA3 PCOLCE

3.65e-061939569ab47b360bee1d4f1092c2269e58acebe9584021
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_119|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL16A1 MYL9 CPXM1 ITGA1 FHL2 PCOLCE

3.65e-06193956e2ee077fd381bd906e6b4329f22e7d106e422a7f
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Degenerative_Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL16A1 MYL9 CPXM1 ITGA1 FHL2 PCOLCE

3.76e-0619495629f83cdd63314fff41258937d70b881a5503bfcc
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_119|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL16A1 MYL9 CPXM1 ITGA1 FHL2 PCOLCE

3.76e-06194956d3db241ea316bbcde6d16618193b474591ad5ce4
ToppCellIPF-Stromal-Myofibroblast|IPF / Disease state, Lineage and Cell class

COL16A1 MYL9 COL6A6 CPXM1 EPHA3 PCOLCE

3.99e-061969562d0a48e49b3b37bb66e33e74c52915911e1f8a74
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL16A1 MYL9 CPXM1 ITGA1 FHL2 PCOLCE

4.11e-061979564cf4e9553397cd8dee883dbec24f41bec41aff99
ToppCell10x_3'_v2v3-Neoplastic-Differentiated-like-AC-like-AC-like_Prolif-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SOX9 HS6ST2 ITGA2 ECT2 EPHA3 CCNA2

4.23e-061989561fa213e79d828bff6465bde116536dd1b80d94e0
ToppCellBiopsy_Other_PF-Mesenchymal-Myofibroblasts|Biopsy_Other_PF / Sample group, Lineage and Cell type

COL16A1 COL6A6 FHL2 TMEM200A EPHA3 PCOLCE

4.48e-06200956e504570fd7eec1524c401b1cfa9d10822d80d994
ToppCell10x5'v1-week_14-16-Mesenchymal_osteo-stroma-osteochondral_precursor|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

COL16A1 ENPP2 CPXM1 ITGA1 EPHA3 PCOLCE

4.48e-06200956ad3fb8ef0be45032369d1325024787fbe1dfb8d6
ToppCellwk_20-22-Mesenchymal-Fibroblast-intermediate_fibro|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

COL16A1 COL6A6 ENPP2 CPXM1 KAZN PCOLCE

4.48e-06200956d769723f8fcb37d9b86589e0c41c1d7f16393cfe
ToppCell(5)_Fibroblast-B_(Myofibroblast)|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

COL16A1 MYL9 CPXM1 FHL2 EPHA3 PCOLCE

4.48e-062009569bbaa666d0f3b4782c1b4b95e0fa5fc1467842d8
ToppCellSubstantia_nigra-Endothelial-ENDOTHELIAL_TIP|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

SCN4A ABCB11 CPXM1 FHL2 PCOLCE

2.32e-05159955cb2470b288c13e454a2a80115b0d5613b3f718e6
ToppCelldroplet-Limb_Muscle-nan-3m-Myeloid-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HS6ST2 PI4KA ANKMY2 IRF6 ITGA2

2.85e-051669550a7992bc673fca546636563ec3fc17a4298ab6b1
ToppCellE18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SCG3 ZBTB40 ITGA1 TMEM200A PCOLCE

2.94e-05167955b0eb7a40491dd2432f5282f578ce569df86d21a7
ToppCell343B-Myeloid-Dendritic-cDC_activated|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

SOX9 FNBP1 RAB10 SYDE2 L3MBTL4

3.11e-05169955e68e6c24606fd46eca6f86bb63fa86ea17879ae2
ToppCelldroplet-Skin-nan-18m-Epithelial-keratinocyte_stem_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGEF40 MYL9 ENPP2 CPXM1 FHL2

3.20e-0517095510e0912dd0beab5d0bbe2bd49e477b5962687925
ToppCellBAL-Control-Lymphocyte-T/NK-Other_T|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

INTS6L GPR19 ITGA2 CCNA2 EPHA4

3.57e-0517495594575a605c725de83f66a6cf7df9d7bb360ffc56
ToppCellBAL-Control-Lymphocyte-T/NK-Other_T-T/NK_proliferative|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

INTS6L GPR19 ITGA2 CCNA2 EPHA4

3.57e-0517495540c81ab36d7931e271e20d7d56fed32463c75f41
ToppCellBAL-Control-Lymphocyte-T/NK-Other_T-T/NK_proliferative-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

INTS6L GPR19 ITGA2 CCNA2 EPHA4

3.57e-05174955b43fb0fbb492c1be6e791a1c4d6c4e5956955ee4
ToppCellfacs-Heart-RV-18m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYL9 SYDE2 BRINP2 DGKB DGKG

3.67e-05175955d8e385320f554d974538b7cdc4f8e4767f1455f2
ToppCellE18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_G2M|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYL9 HS6ST2 DGKB ITGA1 CCNA2

3.67e-051759553e56695a9db97cb1d3503425c48eb79bbf99213e
ToppCellfacs-Heart-RV-18m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYL9 SYDE2 BRINP2 DGKB DGKG

3.67e-05175955cf15465855602ba135752c18755e3e058dbd42ec
ToppCellfacs-Heart-LA-24m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYL9 BRINP2 DGKB DGKG CYB5R2

3.87e-0517795532fecefba1a55e1f418c9a055236fa11175c692d
ToppCellfacs-Heart-LA-24m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYL9 BRINP2 DGKB DGKG CYB5R2

3.87e-051779551b153fbfe1323dc589de4af73a52149ea5ce6763
ToppCell3'-Child09-12-SmallIntestine-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

EFCAB5 MYL9 SCN4A DGKB DGKG

3.87e-05177955d731400997afea379f47ae8aa0f82802962b0861
ToppCell10x5'v1-week_12-13-Mesenchymal_osteo-stroma-osteochondral_precursor|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

ENPP2 SCG3 ITGA1 ITGA2 EPHA3

4.09e-0517995598c0c5c8034ae8a4b3ceea7fd1d0386ee5f89d09
ToppCell3'-GW_trimst-2-LargeIntestine-Mesenchymal-myocytic-SMC_(PLPP2+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FNBP1 MYL9 SYDE2 ITGA1 FHL2

4.09e-05179955e860dca9b28ac5af61804bfd729cd39257cdb352
ToppCellhuman_hepatoblastoma-Tumor_cells-T6|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

RGL1 DGKG KAZN ITGA2 HTRA4

4.09e-0517995514fc8ccb6b215063d747643f47d780d2b237eb67
ToppCellfacs-Heart-RV-24m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYL9 BRINP2 DGKB DGKG CYB5R2

4.20e-05180955a37cc885fe3f6cb9df69d43358064c83c18412e7
ToppCellfacs-Heart-RV-3m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYL9 DGKB DGKG CFAP69 CYB5R2

4.20e-051809550059e5acade6c895fd629767bea1c15f40b0d1b0
ToppCellfacs-Heart-RV-24m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYL9 BRINP2 DGKB DGKG CYB5R2

4.20e-0518095563a6d532b16b8b15c7c9102148d7297ee3afd641
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PDZK1 DGKB FGGY L3MBTL4 SORCS1

4.20e-051809551363b3254470f6ff98630d1df83a1bdbacc137e0
ToppCellfacs-Heart-RV-3m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYL9 DGKB DGKG CFAP69 CYB5R2

4.20e-05180955dfb8412e1e06fa7349e66eea2ef27d9ea98b7893
ToppCellfacs-Lung-EPCAM-3m-Mesenchymal-Myofibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNB1 MYL9 ENPP2 DGKB FHL2

4.20e-05180955d67d3196e6cc3dcd31023a4dc69310226181d583
ToppCellfacs-Lung-EPCAM-3m-Mesenchymal-pulmonary_interstitial_fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNB1 MYL9 ENPP2 DGKB FHL2

4.20e-05180955573308d43425d9fba20787abdb7f8efefc48efb5
ToppCellPND14-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_G2M|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ATP13A3 DCK ECT2 TTK CCNA2

4.42e-0518295521dcab170ffeef89faa9fee5008568cb6e15c694
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PDZK1 DGKB SLC26A9 FGGY L3MBTL4

4.42e-051829554a9c13932e7163fd37a3dcc4c6ca3bbea5372459
ToppCellfacs-Heart-LA-3m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYL9 BRINP2 DGKB DGKG SORCS1

4.54e-051839558d45dff06a199b1369576657f7f9dc0249c5f841
ToppCelldroplet-Lung-18m-Hematologic-myeloid-classical_monocyte_proliferating|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

EFCAB5 ECT2 TTK CCNA2 ALG13

4.54e-051839556c1d7ce60e67bf1df364a4e177c351e7313eb41f
ToppCelldroplet-Kidney-nan-21m-Epithelial-Pecam____kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYL9 BRINP2 ABCB11 DGKB FHL2

4.54e-05183955f55081068213cc1cdb2acad58ff10f6b48b44c72
ToppCellfacs-Heart-LA-3m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYL9 BRINP2 DGKB DGKG SORCS1

4.54e-05183955421265fa15d5a028cb567bb0904e670473ef102b
ToppCelldroplet-Lung-30m-Mesenchymal-myofibroblast|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

COL16A1 MYL9 ENPP2 DGKB TMEM200A

4.66e-0518495555dde9c4eebac2a33788c1ff1d8fe312d150fad4
ToppCell3'-Airway_Nasal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_acinar_cell-SMG_duct-SMG_duct_L.0.6.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SOX9 RPS15 BRINP2 FGGY CYB5R2

4.66e-0518495500db9eaaffe9c598222e14b2f9638cbcce1602d7
ToppCelldroplet-Lung-30m-Mesenchymal-myofibroblast-pericyte_cell-pericyte|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

COL16A1 MYL9 ENPP2 DGKB TMEM200A

4.66e-051849557128a2be291544d3df3ed6c80f21ddda8437dcba
ToppCelldroplet-Lung-30m-Mesenchymal-myofibroblast-pericyte_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

COL16A1 MYL9 ENPP2 DGKB TMEM200A

4.66e-05184955d14238f7b0b55a4c8d7040bea854bd221a66ac30
ToppCellfacs-Lung-24m-Mesenchymal-myofibroblast-pericyte_cell-pericyte|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

COL16A1 MYL9 ENPP2 DGKB TMEM200A

4.78e-05185955a6cd90f8f30c7bdf66958cf403e73c193aa32f5e
ToppCellfacs-Skin-nan-24m-Mesenchymal|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RGL1 ENPP2 CPXM1 CFAP69 PCOLCE

4.78e-051859558433a337625ff8398520e223ef92bf9bb0beb14c
ToppCellfacs-Skin-nan-24m-Mesenchymal-fibroblast|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RGL1 ENPP2 CPXM1 CFAP69 PCOLCE

4.78e-05185955049d793d043d5d434f143025de49dd210d18756c
ToppCellfacs-Skin-nan-24m-Mesenchymal-nan|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RGL1 ENPP2 CPXM1 CFAP69 PCOLCE

4.78e-0518595563200c42565eea596f9b00728e70e544b8d50a7f
ToppCellfacs-Lung-24m-Mesenchymal-myofibroblast-pericyte_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

COL16A1 MYL9 ENPP2 DGKB TMEM200A

4.78e-051859555053f932e2adfcf4d6faaecff2999ac53d8d7aa5
ToppCelldroplet-Spleen-SPLEEN-1m-Lymphocytic-immature_NKT_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CPXM1 FHL2 ECT2 TTK CCNA2

4.78e-05185955736bf89a7a1a840ab6920060f2d98598332065a0
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RGL1 PDZK1 DGKB FGGY L3MBTL4

4.91e-05186955a417e1e21313a7e05951038cdef5ac672a9f727c
ToppCellE16.5-samps-Mesenchymal-Myofibroblast|E16.5-samps / Age Group, Lineage, Cell class and subclass

MYL9 ENPP2 FHL2 EPHA3 SORCS1

4.91e-05186955e044b3428b7eacfdc72d0f57cdabaa1de04c74cd
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NWD2 FHL2 EPHA3 EPHA4 SORCS1

5.03e-05187955f18628ffc7ff7c762b8339ba8822cf0c3157f469
ToppCellCOVID-19_Mild-Neu_4|COVID-19_Mild / 5 Neutrophil clusters in COVID-19 patients

TCP11L1 CPSF3 PTGR3 CCNA2 VAT1

5.03e-05187955714851e757c71c559ee6413a3f61d6c117c79ad2
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MYL9 DGKB DGKG ITGA1 EPHA3

5.03e-0518795548bfdb3504c3fefe5db3abac4b790c369680ab4e
ToppCellCOVID-19-kidney-Stressed_PCT|kidney / Disease (COVID-19 only), tissue and cell type

ENPP2 PDZK1 FGGY L3MBTL4 SORCS1

5.03e-05187955acd305475f3609800af0d7bc68d83ef41228080b
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MYL9 DGKB DGKG ITGA1 EPHA3

5.03e-05187955958402fcc78f4c7a7d13d659d776f3817137975f
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NWD2 FHL2 EPHA3 EPHA4 SORCS1

5.16e-0518895550c1b1d690f0e9443082f2adf4f1b8e9ce4cd337
ToppCellCOVID-19-kidney-DCT|kidney / Disease (COVID-19 only), tissue and cell type

CACNB4 HS6ST2 ARHGEF38 KAZN ITGA2

5.16e-05188955df1fd0819d301679f3c9ea404e942e39095912eb
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_myocytic|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

FNBP1 MYL9 ITGA1 FHL2 L3MBTL4

5.29e-05189955b6d5dec55bf352f6ae19d8f488ae70aa10fb9a8f
ToppCell10x3'2.3-week_17-19-Mesenchymal_osteo-stroma-osteochondral_precursor|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

COL16A1 MYL9 ITGA1 EPHA3 PCOLCE

5.29e-051899551ff4f8da572bdc6356e9df9f41a7f62c81d4c570
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MYL9 DGKB DGKG ITGA1 EPHA3

5.29e-05189955fac5c291a9a87418bb0878c3d624829bdbf1f428
ToppCell(2)_Fibroblasts-(22)_Fibro-3|World / Cell class and subclass of bone marrow stroma cells in homeostatis

ENPP2 CPXM1 TMEM200A CYB5R2 PCOLCE

5.43e-051909553aed03b87ba2c8d479048c3ceef3ff5e38746c28
ToppCell3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-myocytic-SMC_(PLPP2+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FNBP1 MYL9 SYDE2 ITGA1 FHL2

5.43e-05190955e102622f05c7f3e1bd8b224ea159d57033793ee0
ToppCellPND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYL9 KAZN ITGA1 TMEM200A PCOLCE

5.43e-051909551004e89d99c9d46c78b7d3532d8d4aadb81a96fd
ToppCelldroplet-Spleen-nan-18m-Lymphocytic-immature_NKT_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FHL2 ECT2 TTK EPHA3 CCNA2

5.43e-05190955b99271d139c8d01e20feb95d99f79c9b2756b4cb
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_2_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CACNB4 COL6A6 KAZN CFAP69 EPHA3

5.43e-051909550fea33f2dc1efa23aaa2da1c318482a52a313ff1
ToppCellPND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYL9 KAZN ITGA1 TMEM200A PCOLCE

5.43e-0519095510b02c62e72bfea9767e3e751011436925da823e
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-smooth_muscle_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR19 MYL9 DGKB DGKG ITGA1

5.43e-051909551ab3f19f1ce9f58e5125135704d94655a2e330a0
ToppCellP07-Mesenchymal-developing_mesenchymal_cell|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MYL9 ITGA1 TMEM200A CCNA2 PCOLCE

5.56e-05191955ddbc5f97f2aef19be4ad93db4139876c939b848e
ToppCell3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-myocytic|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FNBP1 MYL9 SYDE2 ITGA1 FHL2

5.56e-05191955de2cd94ee88a7754f86d39469e38374d668210c7
ToppCellStriatum-Macroglia-POLYDENDROCYTE|Striatum / BrainAtlas - Mouse McCarroll V32

RAB10 TCP11L1 ECT2 TTK ALG13

5.56e-051919556bc9c7c86040f3ebce08c350e625e345581d4550
ToppCelldroplet-Heart-4Chambers-21m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX9 ARHGEF40 ENPP2 CPXM1 PCOLCE

5.56e-05191955f892f725a32e704cd18fec2f6d1db82993e7e79a
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_2_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CACNB4 COL16A1 COL6A6 EPHA3 PCOLCE

5.70e-051929558d56e360ebc624ca4cd7f0af4f3cc599c244f134
ToppCellfacs-Pancreas-Exocrine-3m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL16A1 MYL9 CPXM1 EPHA3 PCOLCE

5.70e-051929558937a59f6bbe07f671bdabbd3707dc9c17a14cd9
ToppCellControl-Endothelial-VE_Arterial|Endothelial / Disease state, Lineage and Cell class

FNBP1 CPAMD8 ENPP2 ATP13A3 EPHA4

5.70e-051929557e89b9125e8b85f6be85eeccef5c8644647ab0e1
ToppCellfacs-Pancreas-Exocrine-3m-Mesenchymal|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL16A1 MYL9 CPXM1 EPHA3 PCOLCE

5.70e-05192955e4a7f2673f801b008ca67291db2fb2b9fd2955b8
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL16A1 COL6A6 ENPP2 CPXM1 PCOLCE

5.70e-05192955beac6b3c191b11add8e39e8d04562b478ea8929e
ToppCellfacs-Pancreas-Exocrine-3m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL16A1 MYL9 CPXM1 EPHA3 PCOLCE

5.70e-05192955ac1477433704573f95111eee6263b93668d2845e
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

COL16A1 COL6A6 CPXM1 EPHA3 PCOLCE

5.70e-05192955e0f4e4470a71bfa81d9dcd8594e5f82aafc24f81
ToppCellMesenchymal-matrix_fibroblast_2_cell|World / Lineage, Cell type, age group and donor

COL16A1 COL6A6 KAZN EPHA3 PCOLCE

5.70e-05192955a769158c49d2b208c4224d85e7ae68c85cc372ed
ToppCelldroplet-Lung-30m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ARHGEF40 COL16A1 ENPP2 HTRA4 PCOLCE

5.84e-0519395564edc1d6fb0fe117767d494cf4a5723bf8be2804
ToppCellfacs-Heart-LA-18m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX9 MYL9 CPXM1 HTRA4 PCOLCE

5.84e-05193955124364adb3ded77282d449dd2cb039e6f2403a39
ToppCellControl-Stromal-Myofibroblast|Stromal / Disease state, Lineage and Cell class

COL6A6 ENPP2 ITGA1 ITGA2 L3MBTL4

5.84e-051939555896242f713ae5fd1a4ebb63827f15d7279dced2
ToppCelldroplet-Heart-nan-3m-Mesenchymal-fibroblast|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX9 ARHGEF40 COL6A6 CPXM1 PCOLCE

5.99e-05194955ce32e60bcea1b8baf496ce9050832bc8c77d8434
ToppCelldroplet-Liver-LIVER-NPC-1m-Mesenchymal-hepatic_stellate_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL16A1 MYL9 FHL2 EPHA3 PCOLCE

5.99e-05194955415801a3dfacf05f2b603fb424df3d045190a812
ToppCelldroplet-Pancreas-Exocrine-21m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL16A1 MYL9 CPXM1 CCNA2 PCOLCE

5.99e-05194955775600880bb77781de48085d8744c1030223de1f
ToppCelldroplet-Heart-nan-3m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX9 ARHGEF40 COL6A6 CPXM1 PCOLCE

5.99e-05194955a1dc157148885cc8d3685ac81a1f4e3562aeecc9
ToppCelldroplet-Lung-LUNG-1m-Myeloid-Proliferating_Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATP13A3 DCK ECT2 TTK CCNA2

5.99e-05194955effd38e51062b225ecabc7e1c50154e65495d559
ToppCelldroplet-Liver-LIVER-NPC-1m-Mesenchymal-hepatic_stellate_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL16A1 MYL9 FHL2 EPHA3 PCOLCE

5.99e-05194955256cb33ec90328f2704921fb0fe0fd9812e138b0
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_adventitial_fibro_(9)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

COL16A1 COL6A6 KAZN EPHA3 PCOLCE

5.99e-0519495599577a5a631e607b5abe7a1b0d8d6a5eabe50196
ToppCellRA|World / Chamber and Cluster_Paper

MYL9 ATP13A3 KAZN L3MBTL4 SORCS1

5.99e-0519495508f0afbb68a63150fbe107a5337299081c3f69e4
DiseaseMalignant neoplasm of breast

RGL1 PBRM1 CSNK1D PDZK1 ARHGEF38 DGKG FEM1C FHL2 ECT2 CPSF3 CNR2 HNRNPL SORCS1

4.02e-0510749513C0006142
Diseasesyndromic X-linked intellectual disability Najm type (implicated_via_orthology)

CSNK1D CSNK1E

2.13e-047952DOID:0060807 (implicated_via_orthology)
DiseaseCongenital myopathy (disorder)

SCN4A NEB

6.63e-0412952C0270960
Diseaseresponse to beta blocker, heart rate

RGL1 POLI KAZN

8.34e-0457953EFO_0004326, EFO_0007766
Diseaseresponse to antipsychotic drug

ARHGEF38 SLC26A9 FGGY

9.69e-0460953GO_0097332
Diseaseforced expiratory volume

CLUAP1 PBRM1 ENPP2 SCN4A ARHGEF38 ZBTB40 DGKB VTA1 ITGA1

1.01e-03789959EFO_0004314
DiseaseAstrocytosis

ITGA1 ITGA2

1.35e-0317952C3887640
DiseaseGliosis

ITGA1 ITGA2

1.35e-0317952C0017639
Diseasepulse pressure measurement

PBRM1 GPR19 ENPP2 RPS15 ABCB11 CPXM1 ITGA1 BRD1 FHL2 CFAP69 FGGY CCNA2

1.70e-0313929512EFO_0005763
Diseasememory performance

PBRM1 KLF3 KAZN NEB EPHA4 SORCS1

2.11e-03409956EFO_0004874
DiseaseAtaxia

CACNB4 AP2M1

2.93e-0325952C0004134

Protein segments in the cluster

PeptideGeneStartEntry
YMKMEPVKELTGGGT

BRD1

361

O95696
TGEKAMMLLGQVKYG

CETP

61

P11597
GKHKNKPDMNYETMG

ELF1

251

P32519
KEVYMTMAYGKGDPL

ALG13

596

Q9NP73
MVSMGIGNKPFLDIK

ARHGEF40

1386

Q8TER5
GPSLKGYEVTDMMQK

CACNB1

236

Q02641
TMSGQKLPLKMSVDY

CPSF3

376

Q9UKF6
EMEGKYVINMPKGTT

C19orf47

206

Q8N9M1
KMDAYMKGAPEAIAG

ATP13A3

646

Q9H7F0
VPGSMGDMVNYDEIK

COL16A1

1426

Q07092
IYMQEGKPNLLDMGS

ARHGEF38

221

Q9NXL2
MAKKNYVGISEIPSM

GPR19

366

Q15760
GLKLYVMEMSDKPGE

CPXM1

331

Q96SM3
MDNIKYGDNTKEIPM

ABCB11

1171

O95342
GGKPLEVEMAGIEYM

ASCC1

241

Q8N9N2
SMGKGMLPYDVQIID

ACSM4

391

P0C7M7
GPSLKGYEVTDMMQK

CACNB4

226

O00305
GLDSNPMKDYMILSG

CNR2

16

P34972
KIPEMGKYMDITGTE

NWD2

271

Q9ULI1
GAMGIMLVYDITNGK

RAB10

81

P61026
YPEGGKMTQYLENMK

CYB5R2

96

Q6BCY4
PMKKGVSYLLMGQVE

PCOLCE

391

Q15113
LQKDMGVMQGTVPYL

RGL1

406

Q9NZL6
EMTEMQGGKYLPLGD

ECT2

291

Q9H8V3
PNEAVYTKMMTKKPG

G6PD

396

P11413
TFGNPFKQDKKGMMI

INTS6L

581

Q5JSJ4
KGVYMTDITPQGVAM

PDZK1

156

Q5T2W1
AKMEKDGYGMTPLLS

FEM1C

206

Q96JP0
GISPKKSKYMTPMQQ

PBRM1

646

Q86U86
MESMKPNKYGVIYST

KLF3

26

P57682
TKMMTPEVLAEAYGK

NT5DC1

91

Q5TFE4
MPMYVKACTENVKSG

KAZN

461

Q674X7
YGGDISKMQMGIPDD

MFI

276

Q8NCR3
KCKPVMIITEYMENG

EPHA4

691

P54764
LGKNPTDEYLEGMMS

MYL9

61

P24844
IESKIYKMMQGGVGI

CSNK1D

51

P48730
FMEYMPGGSIKDQLK

MAP3K2

436

Q9Y2U5
VMSGKKSQPSMYEQL

PI4KA

551

P42356
GPMSKEFQVGMKLEA

L3MBTL4

186

Q8NA19
VMKSYLSGMPECKFG

AP2M1

201

Q96CW1
GAPMYMGTEKEEQGK

ITGA1

511

P56199
VGAPMYMSDLKKEEG

ITGA2

511

P17301
NMKGAMLTNTGKYAI

RBBP6

206

Q7Z6E9
KSSENGVDYVIMGMP

OGDH

296

Q02218
EGAMEMGQIYTGLKS

DGKG

711

P49619
KTDNYMYAKMPGEGL

EFCAB5

1486

A4FU69
GGKELGMKDSDMDYV

HTRA4

301

P83105
EKKVYNIPGISPDMM

KLHL10

76

Q6JEL2
TKMKDVYLKNPQMGD

FNBP1

436

Q96RU3
MMYGKKVLSQEPSSF

CHD6

1706

Q8TD26
YVGGVMSVEMQAPKL

FGGY

136

Q96C11
MGTCAEVYMKLSVPK

CPAMD8

831

Q8IZJ3
EGAMEMGQIYTGLKS

DGKB

721

Q9Y6T7
GMTPLMHAAYKGKLD

ANKMY2

46

Q8IV38
KSKPVMIVTEYMENG

EPHA3

691

P29320
KTIMPGTRKMEYKGS

FHL2

106

Q14192
GKHKNKPDMNYETMG

ELF2

251

Q15723
KSKPGAAMVEMADGY

HNRNPL

416

P14866
KIFGPMASVGNMDEK

HS6ST2

136

Q96MM7
KNGGNVLQMMYEKPE

DCK

76

P27707
GGTYMLNKPVDDIIM

GDI1

246

P31150
IYMPAVLEGTGKSQM

HYAL1

246

Q12794
MPGVKLTTQAYCKMV

EMC8

1

O43402
KVGYMKKQPDITNSM

CCNA2

196

P20248
AGTNGYMAPEILMEK

GRK7

351

Q8WTQ7
YKIQMAEVGGLAKTM

CFAP69

186

A5D8W1
KLGTGNYDVMTPMVD

POLI

396

Q9UNA4
ASYMKKGSKVMPNIE

ENPP2

176

Q13822
PVKEVGMYGKIAVME

DDB1

51

Q16531
GSIGPENFSKMKTFM

COL6A6

631

A6NMZ7
MYDGTKEVPMNPVKI

IRF6

96

O14896
KIGENYSKMDGPEVM

SYDE2

1121

Q5VT97
MTQKYKHALPVGGMA

TCP11L1

276

Q9NUJ3
VSDPEKVGDGMNAYM

SNX2

146

O60749
FSTYGKIKMIDMPVE

RNPS1

181

Q15287
SDQKPDVMYADIGGM

PSMC4

156

P43686
PEKEGLLANTMSKMY

SCN4A

1766

P35499
NSKGYMKLENKEDPM

TMEM200A

426

Q86VY9
AISGGCKMPKKYHMQ

SLC26A9

296

Q7LBE3
KYMRAQMEPGSAVGA

POLR3A

1021

O14802
PFMKMTDEQEKGLSG

SOX9

6

P48436
LEMTDPSKNLGYMKI

BRINP2

666

Q9C0B6
TSVLYNAMKTKGMEG

CLUAP1

101

Q96AJ1
FKKEGIMNPEVGMKY

NLN

651

Q9BYT8
LPEMVGSMVGVYNGK

RPS15

86

P62841
ATMSYLLGGGMKQED

TTC19

161

Q6DKK2
YAMQTGMKIDSKTPE

VTA1

41

Q9NP79
MTYESQGPDEKMVKY

ZDBF2

1636

Q9HCK1
MYMGKNTGKIVVELP

PTGR3

356

Q8N4Q0
LKPMGKVVTYGMANL

VAT1

276

Q99536
MAKGTTEEMKYVLGQ

TTK

801

P33981
KCMQGKYAGAMESEP

SORCS1

706

Q8WY21
KMMVKYGTISPEEGV

SCG3

311

Q8WXD2
EMMYTGKLPVGKHNF

ZBTB40

76

Q9NUA8
IESKFYKMMQGGVGI

CSNK1E

51

P49674
MQTETPEYKMNKKAG

NEB

326

P20929