Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	lamin binding	SYNE1 DMD HNRNPK	9.57e-05	19	95	3	GO:0005521
GeneOntologyMolecularFunction	extracellular matrix structural constituent	COL6A3 COL11A2 VTN VWF HMCN2 LAMA1	2.79e-04	188	95	6	GO:0005201
GeneOntologyBiologicalProcess	neuron projection morphogenesis	EPHB3 IL1RAPL1 CACNA1F HMCN2 SEMA7A SYNE1 LAMA1 CC2D1A LAMC3 EIF2AK4 DMD MECP2 HNRNPK MOV10	1.07e-05	802	91	14	GO:0048812
GeneOntologyBiologicalProcess	plasma membrane bounded cell projection morphogenesis	EPHB3 IL1RAPL1 CACNA1F HMCN2 SEMA7A SYNE1 LAMA1 CC2D1A LAMC3 EIF2AK4 DMD MECP2 HNRNPK MOV10	1.35e-05	819	91	14	GO:0120039
GeneOntologyBiologicalProcess	cell projection morphogenesis	EPHB3 IL1RAPL1 CACNA1F HMCN2 SEMA7A SYNE1 LAMA1 CC2D1A LAMC3 EIF2AK4 DMD MECP2 HNRNPK MOV10	1.49e-05	826	91	14	GO:0048858
GeneOntologyBiologicalProcess	cell morphogenesis	EPHB3 IL1RAPL1 CACNA1F FRY HMCN2 SEMA7A SYNE1 LAMA1 CDC42EP2 CC2D1A LAMC3 EIF2AK4 DMD MECP2 CDH15 HNRNPK MOV10	1.61e-05	1194	91	17	GO:0000902
GeneOntologyBiologicalProcess	muscle structure development	PRICKLE4 COL6A3 FLNC RCAN1 RTL1 SYNE1 LAMA1 SCN8A YBX3 SOX8 DMD TRIP10 MECP2	9.72e-05	858	91	13	GO:0061061
GeneOntologyCellularComponent	Z disc	PRICKLE4 FLNC RTL1 SCN8A DMD	5.74e-04	151	93	5	GO:0030018
GeneOntologyCellularComponent	sarcomere	PRICKLE4 FLNC RTL1 SYNE1 SCN8A DMD	8.64e-04	249	93	6	GO:0030017
GeneOntologyCellularComponent	I band	PRICKLE4 FLNC RTL1 SCN8A DMD	8.80e-04	166	93	5	GO:0031674
GeneOntologyCellularComponent	microtubule organizing center attachment site	KASH5 SYNE1	1.05e-03	11	93	2	GO:0034992
GeneOntologyCellularComponent	meiotic nuclear membrane microtubule tethering complex	KASH5 SYNE1	1.05e-03	11	93	2	GO:0034993
GeneOntologyCellularComponent	nuclear membrane protein complex	KASH5 SYNE1	1.05e-03	11	93	2	GO:0106083
GeneOntologyCellularComponent	nuclear membrane microtubule tethering complex	KASH5 SYNE1	1.05e-03	11	93	2	GO:0106094
GeneOntologyCellularComponent	glial cell projection	DMD AKR1B1 CNGA3	1.20e-03	47	93	3	GO:0097386
Domain	ACTININ_2	FLNC SYNE1 DMD	1.97e-04	23	93	3	PS00020
Domain	ACTININ_1	FLNC SYNE1 DMD	1.97e-04	23	93	3	PS00019
Domain	Actinin_actin-bd_CS	FLNC SYNE1 DMD	1.97e-04	23	93	3	IPR001589
Domain	LAMININ_IVA	LAMA1 LAMC3	6.74e-04	8	93	2	PS51115
Domain	Laminin_B	LAMA1 LAMC3	6.74e-04	8	93	2	PF00052
Domain	LamB	LAMA1 LAMC3	6.74e-04	8	93	2	SM00281
Domain	Laminin_IV	LAMA1 LAMC3	6.74e-04	8	93	2	IPR000034
Domain	DNA/RNA_helicase_DEAH_CS	TTF2 CHD5 DHX57	6.97e-04	35	93	3	IPR002464
Domain	VWFA	COL6A3 VWF HMCN2 PSMD4	7.49e-04	82	93	4	PS50234
Domain	VWA	COL6A3 VWF HMCN2 PSMD4	8.20e-04	84	93	4	SM00327
Domain	DEAH_ATP_HELICASE	TTF2 CHD5 DHX57	8.89e-04	38	93	3	PS00690
Domain	VDCCAlpha1	CACNA1F CACNA1G	1.08e-03	10	93	2	IPR002077
Domain	RWD	DHX57 EIF2AK4	1.31e-03	11	93	2	PF05773
Domain	VWF_A	COL6A3 VWF HMCN2 PSMD4	1.51e-03	99	93	4	IPR002035
Domain	RWD-domain	DHX57 EIF2AK4	1.57e-03	12	93	2	IPR006575
Domain	Ion_trans_dom	CACNA1F SCN8A CACNA1G CNGA3	2.53e-03	114	93	4	IPR005821
Domain	Ion_trans	CACNA1F SCN8A CACNA1G CNGA3	2.53e-03	114	93	4	PF00520
Domain	Laminin_N	LAMA1 LAMC3	2.81e-03	16	93	2	IPR008211
Domain	LamNT	LAMA1 LAMC3	2.81e-03	16	93	2	SM00136
Domain	LAMININ_NTER	LAMA1 LAMC3	2.81e-03	16	93	2	PS51117
Domain	Laminin_N	LAMA1 LAMC3	2.81e-03	16	93	2	PF00055
Domain	Channel_four-helix_dom	CACNA1F SCN8A CACNA1G	2.88e-03	57	93	3	IPR027359
Domain	-	CACNA1F SCN8A CACNA1G	2.88e-03	57	93	3	1.20.120.350
Domain	TF_T-box	TBX4 TBX21	3.18e-03	17	93	2	IPR001699
Domain	TBOX	TBX4 TBX21	3.18e-03	17	93	2	SM00425
Domain	TF_T-box_CS	TBX4 TBX21	3.18e-03	17	93	2	IPR018186
Domain	-	TBX4 TBX21	3.18e-03	17	93	2	2.60.40.820
Domain	TBOX_3	TBX4 TBX21	3.18e-03	17	93	2	PS50252
Domain	T-box	TBX4 TBX21	3.18e-03	17	93	2	PF00907
Domain	TBOX_1	TBX4 TBX21	3.18e-03	17	93	2	PS01283
Domain	TBOX_2	TBX4 TBX21	3.18e-03	17	93	2	PS01264
Domain	CH	FLNC SYNE1 DMD	4.18e-03	65	93	3	SM00033
Domain	CH	FLNC SYNE1 DMD	5.14e-03	70	93	3	PF00307
Pathway	KEGG_ECM_RECEPTOR_INTERACTION	COL6A3 COL11A2 VTN VWF LAMA1 LAMC3	2.55e-06	84	66	6	M7098
Pathway	REACTOME_NON_INTEGRIN_MEMBRANE_ECM_INTERACTIONS	COL11A2 VTN LAMA1 LAMC3 DMD	7.94e-06	59	66	5	M27218
Pathway	KEGG_FOCAL_ADHESION	COL6A3 FLNC COL11A2 VTN VWF LAMA1 LAMC3	3.87e-05	199	66	7	M7253
Pubmed	Transgenic expression of Laminin α1 chain does not prevent muscle disease in the mdx mouse model for Duchenne muscular dystrophy.	LAMA1 DMD	7.38e-06	2	95	2	21435454
Pubmed	DMD and IL1RAPL1: two large adjacent genes localized within a common fragile site (FRAXC) have reduced expression in cultured brain tumors.	IL1RAPL1 DMD	7.38e-06	2	95	2	18253029
Pubmed	Immunohistological analyses of neutral glycosphingolipids and gangliosides in normal mouse skeletal muscle and in mice with neuromuscular diseases.	CLCN1 DMD	7.38e-06	2	95	2	8595265
Pubmed	Myotonic ADR-MDX mutant mice show less severe muscular dystrophy than MDX mice.	CLCN1 DMD	7.38e-06	2	95	2	10093060
Pubmed	Mutual interference of myotonia and muscular dystrophy in the mouse: a study on ADR-MDX double mutants.	CLCN1 DMD	7.38e-06	2	95	2	10093061
Pubmed	Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.	COL6A3 COL11A2 VTN VWF HMCN2 LAMA1	8.93e-06	175	95	6	28071719
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	BLVRA PALD1 TTF2 CS RPAP1 WDR33 SYNE1 SUPT16H DHX57 PSMD4 YBX3 NUDCD3 ECSIT HNRNPK MOV10	1.29e-05	1496	95	15	32877691
Pubmed	Molecular patterning of the embryonic cranial mesenchyme revealed by genome-wide transcriptional profiling.	EPHB3 VWF LAMA1 LAMC3	2.12e-05	59	95	4	31351040
Pubmed	Identification of CAP as a costameric protein that interacts with filamin C.	FLNC DMD	2.21e-05	3	95	2	17898075
Pubmed	Genetic Evaluation in a Cohort of 126 Dutch Pulmonary Arterial Hypertension Patients.	TBX4 EIF2AK4	2.21e-05	3	95	2	33066286
Pubmed	Chloride channelopathy in myotonic dystrophy resulting from loss of posttranscriptional regulation for CLCN1.	CLCN1 DMD	2.21e-05	3	95	2	17135300
Pubmed	Basal lamina remodeling at the skeletal muscle stem cell niche mediates stem cell self-renewal.	LAMA1 DMD	2.21e-05	3	95	2	29540680
Pubmed	Immunohistochemical detection of neural cell adhesion molecule and laminin in X-linked dystrophic dogs and mdx mice.	LAMA1 DMD	2.21e-05	3	95	2	8040390
Pubmed	KAP1 facilitates reinstatement of heterochromatin after DNA replication.	BLVRA TTF2 RPAP1 WDR33 SUPT16H NAP1L1 PSMD4 TRIP10 HNRNPK MOV10	2.33e-05	704	95	10	29955894
Pubmed	Mechanistic insights into the interactions of NAP1 with the SKICH domains of NDP52 and TAX1BP1.	TAX1BP1 NAP1L1	4.41e-05	4	95	2	30459273
Pubmed	Calcium-binding protein, parvalbumin, is reduced in mutant mammalian muscle with abnormal contractile properties.	CLCN1 SCN8A	4.41e-05	4	95	2	6589628
Pubmed	NR0B1-Related Adrenal Hypoplasia Congenita	IL1RAPL1 DMD	4.41e-05	4	95	2	20301604
Pubmed	RNF43 G659fs is an oncogenic colorectal cancer mutation and sensitizes tumor cells to PI3K/mTOR inhibition.	CHD5 PSMD4 YBX3 HNRNPK MOV10	5.55e-05	148	95	5	35676246
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	COL6A3 FLNC VWF SYNE1 TAX1BP1 SUPT16H NAP1L1 HNRNPK	6.74e-05	497	95	8	23414517
Pubmed	Targeted splice sequencing reveals RNA toxicity and therapeutic response in myotonic dystrophy.	CLCN1 DMD	7.34e-05	5	95	2	33503262
Pubmed	Laminin-111 protein therapy prevents muscle disease in the mdx mouse model for Duchenne muscular dystrophy.	LAMA1 DMD	7.34e-05	5	95	2	19416897
Pubmed	RCAN 1 and 3 proteins regulate thymic positive selection.	RCAN1 LY75	7.34e-05	5	95	2	25783055
Pubmed	Vitronectin increases vascular permeability by promoting VE-cadherin internalization at cell junctions.	VTN DMD	7.34e-05	5	95	2	22606350
Pubmed	NKX2-5, a modifier of skeletal muscle pathology due to RNA toxicity.	CLCN1 DMD	7.34e-05	5	95	2	25168381
Pubmed	Sox8 is a specific marker for muscle satellite cells and inhibits myogenesis.	SOX8 CDH15	7.34e-05	5	95	2	12782625
Pubmed	A molecular mechanism for LINC complex branching by structurally diverse SUN-KASH 6:6 assemblies.	KASH5 SYNE1	7.34e-05	5	95	2	33393904
Pubmed	Osteoprotegerin (OPG) is localized to the Weibel-Palade bodies of human vascular endothelial cells and is physically associated with von Willebrand factor.	VTN VWF	7.34e-05	5	95	2	15799029
Pubmed	The mammalian LINC complex component SUN1 regulates muscle regeneration by modulating drosha activity.	RTL1 DMD	7.34e-05	5	95	2	31686651
Pubmed	HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.	TAF3 VTN WDR33 TAX1BP1 SUPT16H NAP1L1 DHX57 CC2D1A YBX3 EIF2AK4 PIPSL MECP2 MOV10	9.08e-05	1371	95	13	36244648
Pubmed	The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.	COL6A3 VTN VWF HMCN2 LAMA1	9.83e-05	167	95	5	22159717
Pubmed	Developmental regulation of biglycan expression in muscle and tendon.	COL6A3 DMD	1.10e-04	6	95	2	16810681
Pubmed	Structural Analysis of Different LINC Complexes Reveals Distinct Binding Modes.	KASH5 SYNE1	1.10e-04	6	95	2	33058875
Pubmed	HSPB7 interacts with dimerized FLNC and its absence results in progressive myopathy in skeletal muscles.	FLNC DMD	1.54e-04	7	95	2	26929074
Pubmed	Enhanced expression of L-type Cav1.3 calcium channels in murine embryonic hearts from Cav1.2-deficient mice.	CACNA1F CACNA1G	1.54e-04	7	95	2	12900400
Pubmed	Distinct alpha 7A beta 1 and alpha 7B beta 1 integrin expression patterns during mouse development: alpha 7A is restricted to skeletal muscle but alpha 7B is expressed in striated muscle, vasculature, and nervous system.	VWF LAMA1	1.54e-04	7	95	2	8950511
Pubmed	Mouse model resources for vision research.	CACNA1F LAMA1 CNGA3	1.95e-04	41	95	3	21052544
Pubmed	Evolutionary insights into T-type Ca2+ channel structure, function, and ion selectivity from the Trichoplax adhaerens homologue.	CACNA1F CACNA1G	2.05e-04	8	95	2	28330839
Pubmed	Beta1 integrins are required for the invasion of the caecum and proximal hindgut by enteric neural crest cells.	VTN LAMA1	2.05e-04	8	95	2	19633172
Pubmed	Gradual differentiation and confinement of the cardiac conduction system as indicated by marker gene expression.	EPHB3 CACNA1G	2.05e-04	8	95	2	31306714
Pubmed	Hepatitis C virus infection protein network.	VWF FRS3 NAP1L1	2.10e-04	42	95	3	18985028
Pubmed	Agrin has a pathological role in the progression of oral cancer.	SYNE1 SUPT16H PSMD4 DMD HNRNPK	2.12e-04	197	95	5	29872149
Pubmed	Functional specialization of beta-arrestin interactions revealed by proteomic analysis.	NAP1L1 YBX3 EIF2AK4 DMD CNGA3 HNRNPK	2.41e-04	317	95	6	17620599
Pubmed	Comparative mapping of the actin-binding protein 280 genes in human and mouse.	FLNC CLCN1	2.62e-04	9	95	2	8088838
Pubmed	Auditory cortex interneuron development requires cadherins operating hair-cell mechanoelectrical transduction.	ADGRV1 CDH15	2.62e-04	9	95	2	28705869
Pubmed	International Union of Pharmacology. XLVIII. Nomenclature and structure-function relationships of voltage-gated calcium channels.	CACNA1F CACNA1G	2.62e-04	9	95	2	16382099
Pubmed	Cell cycle-dependent phosphorylation regulates RECQL4 pathway choice and ubiquitination in DNA double-strand break repair.	CS HMCN2 RPAP1 ENTR1 SUPT16H NAP1L1 DHX57 YBX3 ECSIT PIPSL HNRNPK MOV10	2.82e-04	1335	95	12	29229926
Pubmed	WWP2 ubiquitylates RNA polymerase II for DNA-PK-dependent transcription arrest and repair at DNA breaks.	WDR33 NAP1L1 DHX57 YBX3 BABAM2 HNRNPK MOV10 KIFC1	2.88e-04	615	95	8	31048545
Pubmed	ZBTB2 protein is a new partner of the Nucleosome Remodeling and Deacetylase (NuRD) complex.	CHD5 SUPT16H NAP1L1 YBX3 MECP2 MOV10	2.98e-04	330	95	6	33301849
Pubmed	High-sensitivity profiling of SARS-CoV-2 noncoding region-host protein interactome reveals the potential regulatory role of negative-sense viral RNA.	WDR33 DHX57 PSMD4 YBX3 HNRNPK MOV10 KIFC1	3.09e-04	469	95	7	37314180
Pubmed	Trophoblast-specific expression and function of the integrin alpha 7 subunit in the peri-implantation mouse embryo.	LAMA1 LAMC3	3.28e-04	10	95	2	11784026
Pubmed	DNA cloning using in vitro site-specific recombination.	IL1RAPL1 PSD2 CLCN1 TAX1BP1 RSPH6A DMD PLEKHH2 MECP2 MOV10	3.29e-04	794	95	9	11076863
Pubmed	HENA, heterogeneous network-based data set for Alzheimer's disease.	SYNE1 CDC42EP2 DMD HNRNPK	3.37e-04	120	95	4	31413325
Pubmed	An Interaction Landscape of Ubiquitin Signaling.	TTF2 WDR33 TAX1BP1 LAMA1 PSMD4 KLHDC10 BABAM2	3.59e-04	481	95	7	28190767
Pubmed	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.	CS WDR33 SYNE1 SUPT16H NAP1L1 DHX57 YBX3 HNRNPK MOV10	3.70e-04	807	95	9	22681889
Pubmed	Wnt regulation: exploring Axin-Disheveled interactions and defining mechanisms by which the SCF E3 ubiquitin ligase is recruited to the destruction complex.	TTF2 FLNC CS NAP1L1 PSMD4 YBX3 DMD HNRNPK KIFC1	3.77e-04	809	95	9	32129710
Pubmed	A human MAP kinase interactome.	FLNC VWF SYNE1 CDC42EP2 PSMD4 DMD HNRNPK	3.82e-04	486	95	7	20936779
Pubmed	Poly(ADP-ribosyl)ation of BRD7 by PARP1 confers resistance to DNA-damaging chemotherapeutic agents.	TTF2 SUPT16H NAP1L1 DHX57 YBX3 HNRNPK MOV10	3.82e-04	486	95	7	30940648
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	PRUNE2 SYNE1 CHD5 CACNA1G ADGRV1	3.91e-04	225	95	5	12168954
Pubmed	Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.	WDR33 ENTR1 TAX1BP1 SUPT16H AKR1B1 BABAM2 MECP2 KIFC1	3.95e-04	645	95	8	25281560
Pubmed	Sox8 and Sox9 act redundantly for ovarian-to-testicular fate reprogramming in the absence of R-spondin1 in mouse sex reversals.	LAMA1 SOX8	4.00e-04	11	95	2	32450947
Pubmed	Slc20a2 deficiency results in fetal growth restriction and placental calcification associated with thickened basement membranes and novel CD13 and lamininα1 expressing cells.	VWF LAMA1	4.00e-04	11	95	2	26952749
Pubmed	Systematic resequencing of X-chromosome synaptic genes in autism spectrum disorder and schizophrenia.	IL1RAPL1 MECP2	4.00e-04	11	95	2	20479760
Pubmed	Hesr1 and Hesr3 are essential to generate undifferentiated quiescent satellite cells and to maintain satellite cell numbers.	DMD CDH15	4.00e-04	11	95	2	21989910
Pubmed	Regional differences in the expression of laminin isoforms during mouse neural tube development.	LAMA1 LAMC3	4.00e-04	11	95	2	21524702
Pubmed	Mutations in LAMB1 cause cobblestone brain malformation without muscular or ocular abnormalities.	LAMA1 LAMC3	4.00e-04	11	95	2	23472759
Pubmed	A conserved KASH domain protein associates with telomeres, SUN1, and dynactin during mammalian meiosis.	KASH5 SYNE1	4.00e-04	11	95	2	22826121
Pubmed	PRMT5 mediates FoxO1 methylation and subcellular localization to regulate lipophagy in myogenic progenitors.	LAMA1 DMD	4.00e-04	11	95	2	37883229
Pubmed	CHK2-BRCA1 tumor-suppressor axis restrains oncogenic Aurora-A kinase to ensure proper mitotic microtubule assembly.	FLNC SUPT16H NAP1L1 PSMD4 HNRNPK MOV10 KIFC1	4.21e-04	494	95	7	26831064
Pubmed	The RNA-binding ubiquitin ligase MKRN1 functions in ribosome-associated quality control of poly(A) translation.	PSMD4 YBX3 MOV10	4.67e-04	55	95	3	31640799
Pubmed	N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.	FLNC VTN VWF PSMD4 CC2D1A HNRNPK	4.73e-04	360	95	6	33111431
Pubmed	Association of granulomatosis with polyangiitis (Wegener's) with HLA-DPB1*04 and SEMA6A gene variants: evidence from genome-wide analysis.	COL11A2 HLA-DOA	4.79e-04	12	95	2	23740775
Pubmed	Secreted TARSH regulates olfactory mitral cell dendritic complexity.	PRUNE2 TBX21	4.79e-04	12	95	2	19302145
Pubmed	Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics.	COL6A3 COL11A2 VTN VWF	5.26e-04	135	95	4	28675934
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	FLNC GGNBP2 WDR33 PCDHGA7 SYNE1 CHD5 SUPT16H DHX57 YBX3 EIF2AK4 DMD MECP2	5.61e-04	1442	95	12	35575683
Pubmed	Maturation of the olfactory sensory neurons by Apaf-1/caspase-9-mediated caspase activity.	SEMA7A TBX21	5.65e-04	13	95	2	20624980
Pubmed	Phosphoproteomic analysis of the developing mouse brain.	RPAP1 NAP1L1 PSMD4 ZNF830 VAMP4	5.87e-04	246	95	5	15345747
Pubmed	Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development.	CACNA1F CLCN1 SCN8A CACNA1G	5.87e-04	139	95	4	16985003
Pubmed	Human Antiviral Protein IFIX Suppresses Viral Gene Expression during Herpes Simplex Virus 1 (HSV-1) Infection and Is Counteracted by Virus-induced Proteasomal Degradation.	WDR33 LAMA1 SUPT16H NAP1L1 MOV10	6.43e-04	251	95	5	28077445
Pubmed	Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.	TAF3 VTN SUPT16H DHX57 CC2D1A MECP2 HNRNPK	6.60e-04	533	95	7	30554943
Pubmed	Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins.	COL6A3 VTN VWF HMCN2	7.06e-04	146	95	4	27068509
Pubmed	Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme.	TFPT TAF3 RPAP1 YBX3 HNRNPK MOV10	7.18e-04	390	95	6	17643375
Pubmed	Proteomics analysis of cardiac extracellular matrix remodeling in a porcine model of ischemia/reperfusion injury.	COL6A3 VTN LAMA1	7.29e-04	64	95	3	22261194
Pubmed	The mammalian INO80 chromatin remodeling complex is required for replication stress recovery.	TFPT INO80D	7.57e-04	15	95	2	25016522
Pubmed	Basement membrane composition in the early mouse embryo day 7.	LAMA1 LAMC3	7.57e-04	15	95	2	15895400
Pubmed	Severe protein aggregate myopathy in a knockout mouse model points to an essential role of cofilin2 in sarcomeric actin exchange and muscle maintenance.	FLNC DMD	7.57e-04	15	95	2	24598388
Pubmed	Subunit organization of the human INO80 chromatin remodeling complex: an evolutionarily conserved core complex catalyzes ATP-dependent nucleosome remodeling.	TFPT INO80D	7.57e-04	15	95	2	21303910
Pubmed	INO80 is required for oncogenic transcription and tumor growth in non-small cell lung cancer.	TFPT INO80D	7.57e-04	15	95	2	27641337
Pubmed	Alternative exon skipping biases substrate preference of the deubiquitylase USP15 for mysterin/RNF213, the moyamoya disease susceptibility factor.	CS PSMD4 HNRNPK	7.63e-04	65	95	3	28276505
Pubmed	Global proteomics of Ubqln2-based murine models of ALS.	TAX1BP1 PSMD4 CC2D1A YBX3 PIPSL	7.66e-04	261	95	5	33277362
Pubmed	Matrix-screening reveals a vast potential for direct protein-protein interactions among RNA binding proteins.	WDR33 NAP1L1 DHX57 ZNF830 MECP2 HNRNPK MOV10 KIFC1	8.33e-04	723	95	8	34133714
Pubmed	Laminin alpha5 is necessary for submandibular gland epithelial morphogenesis and influences FGFR expression through beta1 integrin signaling.	LAMA1 LAMC3	8.64e-04	16	95	2	17601529
Pubmed	Failure of MBNL1-dependent post-natal splicing transitions in myotonic dystrophy.	CLCN1 DMD	8.64e-04	16	95	2	16717059
Pubmed	The mINO80 chromatin remodeling complex is required for efficient telomere replication and maintenance of genome stability.	TFPT INO80D	8.64e-04	16	95	2	23979016
Pubmed	Breakdown of the reciprocal stabilization of QBRICK/Frem1, Fras1, and Frem2 at the basement membrane provokes Fraser syndrome-like defects.	COL6A3 LAMA1	8.64e-04	16	95	2	16880404
Pubmed	Specification of motor axon trajectory by ephrin-B:EphB signaling: symmetrical control of axonal patterning in the developing limb.	EPHB3 TBX4	8.64e-04	16	95	2	19109910
Pubmed	Characterizing ZC3H18, a Multi-domain Protein at the Interface of RNA Production and Destruction Decisions.	WDR33 SUPT16H NAP1L1 ZNF830 YBX3 KLHDC10 HNRNPK MOV10	8.94e-04	731	95	8	29298432
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	ZNF469 TFPT TAF3 HMCN2 CHD5 ENTR1 SUPT16H INO80D MECP2 CDH15	9.54e-04	1116	95	10	31753913
Pubmed	A BRISC-SHMT complex deubiquitinates IFNAR1 and regulates interferon responses.	BABAM2 HNRNPK	9.78e-04	17	95	2	24075985
Pubmed	Negative Regulation of p21Waf1/Cip1 by Human INO80 Chromatin Remodeling Complex Is Implicated in Cell Cycle Phase G2/M Arrest and Abnormal Chromosome Stability.	TFPT INO80D	9.78e-04	17	95	2	26340092
Pubmed	Congenital Muscular Dystrophy Overview – RETIRED CHAPTER, FOR HISTORICAL REFERENCE ONLY	COL6A3 SYNE1	9.78e-04	17	95	2	20301468
GeneFamily	Laminin subunits	LAMA1 LAMC3	7.71e-04	12	63	2	626
GeneFamily	X-linked mental retardation\|Angiotensin receptors	IL1RAPL1 DMD MECP2	8.34e-04	53	63	3	103
GeneFamily	INO80 complex \|SRCAP complex	TFPT INO80D	1.22e-03	15	63	2	595
GeneFamily	T-boxes	TBX4 TBX21	1.76e-03	18	63	2	766
GeneFamily	Calcium voltage-gated channel subunits	CACNA1F CACNA1G	3.68e-03	26	63	2	253
Coexpression	GSE23695_CD57_POS_VS_NEG_NK_CELL_DN	TFPT TAF3 CS TAX1BP1 KLHDC10 AKR1B1 TRIP10	8.49e-06	200	95	7	M7786
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Myeloid-Dendritic-conventional_dendritic_cell\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	IL1RAPL1 PALD1 VTN CLCN1 SEMA7A CYP2S1 TRIP10	1.15e-07	179	95	7	ba64bfb757d6e3be631ee95abfa24b47861f6a14
ToppCell	Children_(3_yrs)-Mesenchymal-airway_smooth_muscle_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	IL1RAPL1 PRUNE2 FLNC VTN HMCN2 DMD	1.02e-06	155	95	6	cd7d95cbcad248670e531d80bb83c55e36ebc573
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Myeloid-Dendritic-conventional_dendritic_cell-DC_c1-CLEC9A\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	IL1RAPL1 VTN SEMA7A SCN8A CYP2S1 TRIP10	1.37e-06	163	95	6	f4fcac0af9967ec34a43c9674aa17b0aa5344cf6
ToppCell	Hippocampus-Endothelial-ENDOTHELIAL_TIP\|Hippocampus / BrainAtlas - Mouse McCarroll V32	COL6A3 FLNC VTN CHP2 LAMA1 LAMC3	1.64e-06	168	95	6	26aa96b2b547d11941cb803995ea3d302ee0518c
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Myeloid-Dendritic\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	IL1RAPL1 PALD1 VTN SEMA7A CYP2S1 TRIP10	2.36e-06	179	95	6	8bd85ee92791996377bcafed198c1bb3c9af4c3c
ToppCell	BAL-Mild-cDC_10\|Mild / Compartment, Disease Groups and Clusters	TTF2 SEMA7A CCDC81 DMD LY75 TRIP10	4.11e-06	197	95	6	c0550d41dd5619b369b590f3d6a61154dd7b2cab
ToppCell	Frontal_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	COL6A3 FLNC CHP2 LAMA1 LAMC3	8.45e-06	129	95	5	856255fbfc7f95642000cfd7704141b2388f7c5c
ToppCell	Substantia_nigra-Endothelial-ENDOTHELIAL_TIP-Dcn_1\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	COL6A3 HLA-DOA CHP2 LAMA1 LAMC3	9.44e-06	132	95	5	893b7ec2a2d8a140cc98575d1beca1189f053e9a
ToppCell	Hippocampus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1\|Hippocampus / BrainAtlas - Mouse McCarroll V32	COL6A3 FLNC CHP2 LAMA1 LAMC3	1.02e-05	134	95	5	b959899c89d3a0363a3cd2309155280e0fe5ba88
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-24m-Macroglial-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLNC CHP2 CDC42EP2 CCDC81 PMM1	1.35e-05	142	95	5	67d4ff3483ae34f77c3325aa0fbd3462ca19ade4
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)-myeloid-myeloid_dendritic-liver_dendritic_cell\|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	PALD1 VTN CLCN1 HLA-DOA CYP2S1	2.12e-05	156	95	5	411c170a7dd65269ae442b8069caf5231bddb116
ToppCell	severe_COVID-19-cDC\|severe_COVID-19 / disease group, cell group and cell class (v2)	PALD1 ZNF469 HLA-DOA CYP2S1 DMD	2.18e-05	157	95	5	ec1978e07e2214048d015d8bb793c1d9991f6e37
ToppCell	Substantia_nigra-Endothelial-ENDOTHELIAL_TIP\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	COL6A3 VTN HLA-DOA LAMA1 LAMC3	2.32e-05	159	95	5	cb2470b288c13e454a2a80115b0d5613b3f718e6
ToppCell	Hippocampus-Endothelial-ENDOTHELIAL_TIP-Dcn_1\|Hippocampus / BrainAtlas - Mouse McCarroll V32	COL6A3 FLNC CHP2 LAMA1 LAMC3	2.32e-05	159	95	5	92049a8d8fc9997d8d0d76500c72596a9b2394e0
ToppCell	Adult-Mesenchymal-airway_smooth_muscle_cell-D231\|Adult / Lineage, Cell type, age group and donor	IL1RAPL1 PRUNE2 FLNC TBX4 CHD5	2.39e-05	160	95	5	d783d29150033e9181c0e30870070268fed3fd85
ToppCell	NS-critical-d_0-4-Myeloid-Monocyte-derived_DC\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	PALD1 ZNF469 TFPT HLA-DOA AKR1B1	3.11e-05	169	95	5	6fe82db874eff0f86e5c0d1cc81322eb9d7874eb
ToppCell	10x5'-Lung-Myeloid_Dendritic-DC1\|Lung / Manually curated celltypes from each tissue	EPHB3 SEMA7A HLA-DOA CYP2S1 DMD	3.38e-05	172	95	5	243b8bb01cbec5c1bf8802cbf8a6153356b4c384
ToppCell	5'-Adult-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	IL1RAPL1 COL6A3 HMCN2 CACNA1G CNGA3	3.87e-05	177	95	5	bd602db857f37869ef76d14c05ef522c509f08ee
ToppCell	Severe-Myeloid-mDC\|Severe / Condition, Lineage, Cell class and cell subclass	PALD1 HLA-DOA NAP1L1 CYP2S1 LY75	4.31e-05	181	95	5	00f2949b609ac21bd2da6fd8f685739eeb2f48ad
ToppCell	Severe-Myeloid-mDC-\|Severe / Condition, Lineage, Cell class and cell subclass	PALD1 HLA-DOA NAP1L1 CYP2S1 LY75	4.31e-05	181	95	5	51ded98c76ec35ab1d24ac3ab98280381daa9831
ToppCell	PND01-03-samps-Mesenchymal-Myofibroblast\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	EPHB3 COL6A3 FLNC LAMC3 CACNA1G	4.42e-05	182	95	5	812dac35b9aa05be48258082e007f6c00e7b4dd8
ToppCell	3'_v3-GI_small-bowel-Myeloid_Dendritic-DC1\|GI_small-bowel / Manually curated celltypes from each tissue	CLCN1 SEMA7A HLA-DOA CYP2S1 DMD	4.66e-05	184	95	5	8e393eea7240584a3cef718bee094e2705ec1891
ToppCell	BAL-Severe-Myeloid-cDC-cDC-cDC_11\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	PALD1 CLCN1 HLA-DOA CYP2S1 DMD	4.66e-05	184	95	5	667846c422cfa27e949a24844a305df859cb6760
ToppCell	BAL-Severe-Myeloid-cDC-cDC-cDC_11\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	PALD1 CLCN1 HLA-DOA CYP2S1 DMD	4.66e-05	184	95	5	a6f8b42982ec0cf44b950a2cd9715d068eec4ecb
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	COL6A3 TBX4 LAMC3 DMD PLEKHH2	4.66e-05	184	95	5	102b6f621a5b551e622f97b12d787c080b052a72
ToppCell	LPS_only-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PRUNE2 COL6A3 TBX4 SYNE1 DMD	4.78e-05	185	95	5	e64e8c98dd88d91f6501d3fb10b60fd2f3c90af3
ToppCell	droplet-Lung-21m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PRUNE2 FLNC VWF SLC16A11 KIFC1	4.91e-05	186	95	5	c116cc9f41971622264434ebe29d18e719b0ae19
ToppCell	droplet-Lung-21m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l30\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	IL1RAPL1 GGNBP2 CHD5 SOX8 DMD	5.03e-05	187	95	5	6f7f293c9cf35261e0e3614e46ec1fb00a701b63
ToppCell	3'_v3-blood-Myeloid_Dendritic-DC2\|blood / Manually curated celltypes from each tissue	PALD1 HLA-DOA EIF2AK4 CYP2S1 DMD	5.03e-05	187	95	5	9f3db9f0e5de34aeabfe5984f675bc7a65435df7
ToppCell	3'_v3-blood-Myeloid_Dendritic\|blood / Manually curated celltypes from each tissue	PALD1 SEMA7A EIF2AK4 CYP2S1 DMD	5.16e-05	188	95	5	239a2162a21d3339da7c1884ab76286346fbf97f
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PRUNE2 COL6A3 TBX4 SYNE1 DMD	5.16e-05	188	95	5	3177b2c1723268d330d3e9f24f9e24492ace6286
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL6A3 LAMC3 CACNA1G DMD PLEKHH2	5.16e-05	188	95	5	997dcfc4f08738ab398d8abc15e4fd2fc6619862
ToppCell	Mesenchymal-chondrocyte\|World / Lineage, Cell type, age group and donor	COL6A3 COL11A2 EXTL1 SOX8 PLEKHH2	5.16e-05	188	95	5	7b1e3f8a941eaa68e89c562129a92314642eec66
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PRUNE2 COL6A3 TBX4 SYNE1 DMD	5.29e-05	189	95	5	7ab1cfc1657277858339f7258a0c4ae9cb42fdf8
ToppCell	(3)_DC_activated\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	VTN SEMA7A CCDC81 LY75 TRIP10	5.29e-05	189	95	5	e977838793fc0eb1499e81018e33e4ccb4a5f0c5
ToppCell	(3)_MNP-(3)_DC_activated\|(3)_MNP / Lung cell shreds - cell class (v4) and cell subclass (v4)	VTN SEMA7A CCDC81 LY75 TRIP10	5.56e-05	191	95	5	0353bf797c4ef237b9bb82460c173c7d03cb8883
ToppCell	COVID-19-Myeloid-DC1\|COVID-19 / Condition, Lineage and Cell class	PALD1 CLCN1 HLA-DOA CYP2S1 DMD	5.56e-05	191	95	5	9e44357cdeca46d2b26124bb063c8422ef930083
ToppCell	LPS_only-Stromal_mesenchymal-Lung_smooth_muscle\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PRUNE2 COL6A3 TBX4 SYNE1 DMD	5.56e-05	191	95	5	08042952431ca1a6fd7dfc13f36eb28643979598
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_chondroblast_(18)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	FRY COL11A2 EXTL1 SOX8 DMD	5.56e-05	191	95	5	273c4a757292a9301de0eaeacdec91c9866be229
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PRUNE2 COL6A3 TBX4 SYNE1 DMD	5.56e-05	191	95	5	7853ac7dff649150e6ff27cd4c8cf7c1fc034ed4
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	EPHB3 LAMA1 TTC14 ADGRV1 PLEKHH2	5.70e-05	192	95	5	ee27d27e3d269764dbe8711d0b37ff9331a298a9
ToppCell	Control-CD8+_T_naive\|Control / Disease condition and Cell class	HLA-DOA MAN1C1 NAP1L1 OXNAD1 YBX3	5.84e-05	193	95	5	627d345baf1940218c61907305705298e473dbab
ToppCell	COVID-19-Fibroblasts-Other_FB\|COVID-19 / group, cell type (main and fine annotations)	IL1RAPL1 COL6A3 TBX4 DMD PLEKHH2	5.84e-05	193	95	5	e6b75be08e33c1de079fb5c02f0b4468128b369c
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 SCN8A PODXL2 CACNA1G CDH15	5.84e-05	193	95	5	5fb7808dd971c1cc64c2bd4f8f1de646fb2d77f4
ToppCell	LPS-antiTNF-Stromal_mesenchymal\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	COL6A3 TBX4 SYNE1 DMD PLEKHH2	5.99e-05	194	95	5	6e13549f697f7478b34fe71f7dd9d63c5d3db22e
ToppCell	normal_Pleural_Fluid-Myeloid_cells-Activated_DCs\|Myeloid_cells / Location, Cell class and cell subclass	VTN NAP1L1 CCDC81 LY75 TRIP10	5.99e-05	194	95	5	30f683725cb13ae32ef6846618801ec78e12397d
ToppCell	PCW_05-06-Mesenchymal\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	IL1RAPL1 COL6A3 TBX4 NAP1L1 PLEKHH2	6.29e-05	196	95	5	dca52c57ba35d9395cdbca8b881f12ece721b10f
ToppCell	PCW_07-8.5-Mesenchymal\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	IL1RAPL1 COL6A3 TBX4 NAP1L1 PLEKHH2	6.29e-05	196	95	5	8e10802f52e5e1853ea4ad34bf9a32a34e6112b5
ToppCell	Bronchial-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_pulmonary\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PRUNE2 FLNC FRY HMCN2 DMD	6.44e-05	197	95	5	bf0520a94ebb1d2f94de9f526d17e0b0e8fe7052
ToppCell	Healthy_donor-cDC\|Healthy_donor / disease group, cell group and cell class (v2)	PALD1 ZNF469 HLA-DOA EIF2AK4 CYP2S1	6.44e-05	197	95	5	b57a27e5b855bbdd1dfa352540599d260dc482aa
ToppCell	Influenza-Influenza_Severe-Myeloid-pDC\|Influenza_Severe / Disease, condition lineage and cell class	PALD1 ZNF469 SEMA7A HLA-DOA TRIP10	6.44e-05	197	95	5	e8e6f71e6dc8a695e4321a18543c1df63dd62f3e
ToppCell	Healthy/Control-cDC\|World / Disease group and Cell class	PALD1 ZNF469 HLA-DOA EIF2AK4 CYP2S1	6.44e-05	197	95	5	4497d4073f4d3e74de907325fba9eb4af5766bf4
ToppCell	Bronchial-10x5prime-Immune_Myeloid-Dendritic_cell-DC_1\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CLCN1 SEMA7A HLA-DOA NAP1L1 CYP2S1	6.44e-05	197	95	5	81dd7f9318f0ba175352e5156c24772427e0b34f
ToppCell	Healthy_donor-cDC\|World / disease group, cell group and cell class (v2)	PALD1 ZNF469 HLA-DOA EIF2AK4 CYP2S1	6.44e-05	197	95	5	a545fe3a80cd721bf01115bbb645753840ec9f40
ToppCell	3'-GW_trimst-1-LargeIntestine-Mesenchymal-immature_mesenchymal_cell-Mesoderm_2_(ZEB2+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL6A3 NAP1L1 LAMC3 PLEKHH2 AKR1B1	6.44e-05	197	95	5	ad6c200a193a15360d17463e18a465ce1b90b8da
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-DC-DC2-Z\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	BLVRA CLCN1 NAP1L1 LY75 TRIP10	6.60e-05	198	95	5	c58e2d3a21fcca9f1accccc5303ca4222b6c8432
ToppCell	droplet-Limb_Muscle-MUSCLE-1m-Mesenchymal-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL6A3 FLNC PODXL2 YBX3 CDH15	6.60e-05	198	95	5	5e70246a9ce199cb2fb5379912b8ab59456219e4
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	COL6A3 SYNE1 NAP1L1 LAMC3 DMD	6.60e-05	198	95	5	a860246bcea847249a78fd2e86ed8e04371060db
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-DC-DC2\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	BLVRA CLCN1 NAP1L1 LY75 TRIP10	6.60e-05	198	95	5	f4ff9520598ebc52b3a1f31eee766957983e16b4
ToppCell	COVID-19-Myeloid-Migratory_DC\|Myeloid / Condition, Lineage and Cell class	VTN SEMA7A DMD LY75 TRIP10	6.60e-05	198	95	5	90f3b227cbc61c268d6d94bc9945a08d83d2d3d5
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-immature_mesenchymal_cell-Mesoderm_2_(ZEB2+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL6A3 NAP1L1 LAMC3 PLEKHH2 AKR1B1	6.75e-05	199	95	5	a95aa72387c9558e0316898eaa9df4de8932af1b
ToppCell	Tracheal-NucSeq-Stromal-Chondrocytic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FRY COL11A2 SYNE1 GYG2 EXTL1	6.92e-05	200	95	5	b5a54b9baf79aea01f76a161f0a39bbe87eb4945
ToppCell	Bronchial-NucSeq-Stromal-Myofibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PRUNE2 FLNC FRY HMCN2 DMD	6.92e-05	200	95	5	a66449b22b39dd6987fc2c3ed160d24564234ced
ToppCell	Tracheal-NucSeq-Stromal-Chondrocytic-Chondrocyte\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FRY COL11A2 SYNE1 GYG2 EXTL1	6.92e-05	200	95	5	f5bd0b30e478dac09f68c46b0781f5f2e7e3c693
ToppCell	343B-Myeloid-Macrophage-FABP4+_Macrophage\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	CYP2S1 LMBRD2 KLHDC10 CCDC7	1.35e-04	122	95	4	a2f343962069253a08faa80fd70723b8488a99ec
ToppCell	Entopeduncular-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn_(Dcn)-\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	FLNC HMCN2 CHP2 LAMA1	1.53e-04	126	95	4	f1f24b06d301c266226d1a59dd28585f5ac68f29
ToppCell	Entopeduncular-Endothelial-ENDOTHELIAL_TIP-Dcn_1\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	FLNC HMCN2 CHP2 LAMA1	1.53e-04	126	95	4	fe6900eb37e4f09465a1276586c73dd38545fa2a
ToppCell	Entopeduncular-Endothelial-ENDOTHELIAL_TIP\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	FLNC HMCN2 CHP2 LAMA1	1.53e-04	126	95	4	3d507f829882d043f633db2612b76936e2042445
ToppCell	Entopeduncular-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	FLNC HMCN2 CHP2 LAMA1	1.53e-04	126	95	4	1ac4cc747e466bc79e33b97608b19ad29a7a6a41
ToppCell	Entopeduncular-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn_(Dcn)\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	FLNC HMCN2 CHP2 LAMA1	1.53e-04	126	95	4	2de551d7a8765afec1da8852727c79fec90f45f8
ToppCell	Tracheal-10x3prime_v2-Immune_Lymphocytic-NK-ILC-T_NK-NK_CD11d\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	ZNF469 PSD2 TBX21	1.98e-04	53	95	3	2147787ed3de18b49f51a8518984c7b6ba9a8cef
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-24m-Macroglial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLNC CHP2 CDC42EP2 CCDC81	2.17e-04	138	95	4	c1a46fbf1beffa12c3d1b78361e0613e2e9e2d13
ToppCell	primary_visual_cortex-Non-neuronal-oligodendrocyte-Oligo-OPC_Pdgfra_Grm5\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ZNF469 COL11A2 PKD1L1 SOX8	2.23e-04	139	95	4	a957ea4e581646c76b16b6a7f89579b8c7ac35b6
ToppCell	droplet-Heart-nan-3m-Hematologic-nan\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HLA-DOA TBX21 CYP2S1 LY75	2.30e-04	140	95	4	ab90f6f30d89761687f8836e3d327d143ce49ed4
ToppCell	primary_visual_cortex-Non-neuronal-leptomeningeal_cell-VLMC-VLMC_Spp1_Col15a1\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	VTN CHP2 LAMA1 LAMC3	2.42e-04	142	95	4	f4e4cde228149d5a536fbf0517ed71d81e296faf
ToppCell	Thalamus-Endothelial-ENDOTHELIAL_TIP-Dcn_1\|Thalamus / BrainAtlas - Mouse McCarroll V32	COL6A3 FLNC LAMA1 LAMC3	3.22e-04	153	95	4	e9c6fb5c41adb6595c66c3a917fe455348279e54
ToppCell	Thalamus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1\|Thalamus / BrainAtlas - Mouse McCarroll V32	COL6A3 FLNC LAMA1 LAMC3	3.22e-04	153	95	4	b8b5ff7d2feea3e3a352fb5530e49f639fe1ff88
ToppCell	Thalamus-Endothelial-ENDOTHELIAL_TIP\|Thalamus / BrainAtlas - Mouse McCarroll V32	COL6A3 FLNC LAMA1 LAMC3	3.22e-04	153	95	4	2513edfae62a44e51d3556675a096723194c966c
ToppCell	PBMC-Severe-Myeloid-cDC-cDC-cDC_11\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	PALD1 HLA-DOA CYP2S1 DMD	3.30e-04	154	95	4	5967a0a33456d5930fc492a700ebb015ac050abb
ToppCell	Frontal_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_1\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	COL6A3 FLNC LAMA1 LAMC3	3.30e-04	154	95	4	65dbb60f636562eeba3dafadae9c0c7db2b27476
ToppCell	PBMC-Severe-Myeloid-cDC-cDC-cDC_11\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	PALD1 HLA-DOA CYP2S1 DMD	3.38e-04	155	95	4	fab281db4c275d51240b122be78713c839ba5a95
ToppCell	Hippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Tox\|Hippocampus / BrainAtlas - Mouse McCarroll V32	HMCN2 PKD1L1 RSPH6A	3.46e-04	64	95	3	bf923a66b17e717b8d3817b9d0e201b82a7e4a88
ToppCell	Hippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Tox-Inhibitory_Gad1Gad2_Cplx3.Tox_(Interneuron,_lacunosum_oriens1?)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	HMCN2 PKD1L1 RSPH6A	3.46e-04	64	95	3	a3e852600c53b11175eb579e92962fa711f5678b
ToppCell	Hippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Tox-Inhibitory_Gad1Gad2_Cplx3.Tox_(Interneuron,_lacunosum_oriens1?)-\|Hippocampus / BrainAtlas - Mouse McCarroll V32	HMCN2 PKD1L1 RSPH6A	3.46e-04	64	95	3	f8f43ad9354c786b418bac54614f96f50e8bea68
ToppCell	facs-Aorta-Heart-18m-Mesenchymal-fibrocyte\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PSD2 CLCN1 OXNAD1 CC2D1A	3.46e-04	156	95	4	5b56217336771baf57d791efcb4e206c6aea83b1
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	COL6A3 NAP1L1 LAMC3 DMD	3.46e-04	156	95	4	d5207dbfbcfb885557ea1378dfe6a56d7102e94a
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	COL6A3 NAP1L1 LAMC3 DMD	3.46e-04	156	95	4	363f1b661048d25895e2b8681c82894c957b29c0
ToppCell	droplet-Lung-3m-Hematologic-myeloid-interstitial_macrophage\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PRUNE2 COL11A2 MAN1C1 CHP2	3.64e-04	158	95	4	9a6d9b541446a6aa9f8ed040b330dbb5c6447076
ToppCell	droplet-Lung-3m-Hematologic-myeloid-interstitial_macrophage-interstitial_macrophage_l12\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PRUNE2 COL11A2 MAN1C1 CHP2	3.64e-04	158	95	4	2438713d2a7e32c647ab3384237ed614f4ec8fec
ToppCell	droplet-Heart-nan-24m-Mesenchymal-nan\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHB3 PSD2 ADGRV1 DMD	3.72e-04	159	95	4	7ad3a91d29639b32f6264c91f401c14a35469ac0
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMA1 ADGRV1 PLEKHH2 CCDC7	3.81e-04	160	95	4	c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell	COVID_non-vent-Lymphocytic-Dendritic-pDC\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	PALD1 SEMA7A HLA-DOA RSPH6A	3.81e-04	160	95	4	61f4cb4eb4313d8318aadbb99595a6cb7fd919f7
ToppCell	COVID_non-vent-Lymphocytic-Dendritic\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	PALD1 SEMA7A HLA-DOA RSPH6A	3.81e-04	160	95	4	34b4f710cfcb6ec370b8b074f3cbfe272f392cec
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMA1 ADGRV1 PLEKHH2 CCDC7	3.81e-04	160	95	4	25c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell	droplet-Lung-nan-3m-Myeloid-Interstitial_Macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 COL11A2 MAN1C1 CHP2	3.90e-04	161	95	4	f1d3287d9cb4e0eec99b3509f5dc4b87ae8c8cc9
ToppCell	PND01-03-samps-Myeloid-Macrophage-macrophage-A\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	BLVRA PRUNE2 CHD5 LY75	3.90e-04	161	95	4	5925ee646aa040550e3f8a164a13c8a5c0353319
ToppCell	droplet-Lung-nan-3m-Myeloid-lung_macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 COL11A2 MAN1C1 CHP2	3.90e-04	161	95	4	110cc7122e3c9f105a11d811d77c8a8852b9de6c
ToppCell	droplet-Heart-nan-24m-Hematologic-nan\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HLA-DOA CYP2S1 LY75 KIFC1	3.90e-04	161	95	4	7e60001637ef0f6fc67ef8a36ab80ebb25b0b0ab
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c09-GZMK-FOS_l\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	TFPT TBX21 SLC16A11 CACNA1G	4.09e-04	163	95	4	e4077e587895c85bc806be05ff5d451088e39468
ToppCell	Globus_pallidus-Endothelial-ENDOTHELIAL_TIP-Dcn_1\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	FLNC CHP2 LAMA1 LAMC3	4.28e-04	165	95	4	570483b43ccb5831feec9337b4664814431d40b1
Disease	Profound Mental Retardation	FRY LAMA1 SCN8A CACNA1G MECP2	7.25e-05	139	91	5	C0020796
Disease	Mental Retardation, Psychosocial	FRY LAMA1 SCN8A CACNA1G MECP2	7.25e-05	139	91	5	C0025363
Disease	Mental deficiency	FRY LAMA1 SCN8A CACNA1G MECP2	7.25e-05	139	91	5	C0917816
Disease	Intellectual Disability	FRY SYNE1 LAMA1 SUPT16H SCN8A CACNA1G MECP2 HNRNPK	7.39e-05	447	91	8	C3714756
Disease	Cerebellar Ataxia	SYNE1 SCN8A	9.35e-05	5	91	2	C0007758
Disease	intellectual disability (is_implicated_in)	IL1RAPL1 CC2D1A DMD	1.08e-04	30	91	3	DOID:1059 (is_implicated_in)
Disease	Mental Retardation, X-Linked 1	IL1RAPL1 DMD MECP2	1.32e-04	32	91	3	C2931498
Disease	venous thromboembolism, factor VII measurement	TTF2 VWF BABAM2	2.21e-04	38	91	3	EFO_0004286, EFO_0004619
Disease	Familial pulmonary arterial hypertension	TBX4 EIF2AK4	2.60e-04	8	91	2	C1701939
Disease	Idiopathic pulmonary hypertension	TBX4 EIF2AK4	3.34e-04	9	91	2	C0152171
Disease	Pulmonary arterial hypertension	TBX4 EIF2AK4	4.17e-04	10	91	2	C2973725
Disease	Connective Tissue Diseases	ZNF469 COL11A2	7.18e-04	13	91	2	C0009782
Disease	2-oxo-hept-3-ene-1,7-dioate hydratase activity	TBX4 EIF2AK4	8.36e-04	14	91	2	C1150929
Disease	Idiopathic pulmonary arterial hypertension	TBX4 EIF2AK4	1.10e-03	16	91	2	C3203102
Disease	muscular dystrophy (is_implicated_in)	COL6A3 SYNE1	1.24e-03	17	91	2	DOID:9884 (is_implicated_in)
Disease	Familial primary pulmonary hypertension	TBX4 EIF2AK4	1.24e-03	17	91	2	C0340543
Disease	sphingosine 1-phosphate measurement	DMD MON1B	1.39e-03	18	91	2	EFO_0800185
Disease	pulmonary non-tuberculous mycobacterial infection	BLVRA CHP2	1.55e-03	19	91	2	MONDO_0018469
Disease	hypertension	COL6A3 VTN SEMA7A AKR1B1 MOV10	2.65e-03	307	91	5	EFO_0000537

Protein segments in the cluster

Peptide	Gene	Start	Entry
FPGPDIEQLTDAFGR	CCDC7	1031	Q96M83
GGLEAFDDFFPVEPV	CHD5	31	Q8TDI0
ARFPATGPGSSDDED	EIF2AK4	721	Q9P2K8
ILENDDPGGVFEFSP	ADGRV1	766	Q8WXG9
DELSRQAPIGGDFPA	DMD	2826	P11532
EFFPLDESGNVVPSD	AKR1B1	121	P15121
RPFAPLSGAAEADEG	RCAN1	31	P53805
RFPLSEAGDPDVGTN	PCDHGA7	151	Q9Y5G6
RSEPDDSDPFSFDGP	NAP1L1	236	P55209
GFPELESGEDQPFSR	PALD1	821	Q9ULE6
SFGGEDPRPELQATA	KASH5	146	Q8N6L0
APGGAEDLEDTQFPS	MON1B	11	Q7L1V2
APGSGFPSEENEESR	PODXL2	76	Q9NZ53
NRCDPESDFGPGEEF	CACNA1F	1396	O60840
GPPLSGFLRDETGDF	SLC16A11	391	Q8NCK7
DAEGSPFRGQRFDPA	NUDCD3	336	Q8IVD9
QFAEPTETLFGPDSG	GGNBP2	606	Q9H3C7
PDSGVLFFESVAPED	HMCN2	841	Q8NDA2
FGEPLSPGEIRFIEN	KIAA2026	601	Q5HYC2
DFSFDRVFPPGSGQD	KIFC1	371	Q9BW19
RVFPPGSGQDEVFEE	KIFC1	376	Q9BW19
LVETFQGTEGRPFDP	CYP2S1	156	Q96SQ9
GPGDFEEPIAFDGSR	IL1RAPL1	81	Q9NZN1
ESGGPDNEDYPLFRE	KLHDC10	116	Q6PID8
RSGSGPEAEAEPLDF	NAT16	41	Q8N8M0
DPFPAVFGDFLGRER	FLNC	2216	Q14315
PPTADRFQAEEYGEG	COL11A2	321	P13942
FFDLAEPSGRAANDP	LY75	21	O60449
DFGLSRFLEDDPSDP	EPHB3	776	P54753
VEIGDFERPFSTPAG	PLEKHH2	1266	Q8IVE3
ASDFEFGVDPSADPE	PIPSL	686	A2A3N6
GGEFFFDPQPADASR	OXNAD1	156	Q96HP4
SDSEPEGFFLGERLP	PRICKLE4	306	Q2TBC4
ELFDRGEFSAAPDPG	GYG2	146	O15488
EGPREGTFAEQRPHF	LINC00482	131	Q8N8I6
EGPEEDGTFDLPFQF	CDC42EP2	71	O14613
LPEFGDFARFDPQGG	HLA-DOA	71	P06340
FGEDAEFLPDPSALQ	BABAM2	86	Q9NXR7
SEPDFFSPSLDGDGD	CACNA1G	1001	O43497
FEPDSSEPIFGKNEG	CCDC81	501	Q6ZN84
QPFFEDPTGAGDLLD	ENTR1	161	Q96C92
DGLTPSSNGFPDGEE	FRS3	351	O43559
PGRTFPVDQFFLEDA	DHX57	721	Q6P158
DPDEGIRFRGFSIPE	CS	86	O75390
FPDGQEESIFPDGTI	CENPJ	1256	Q9HC77
ANTPSGPVEAFDFDE	COL6A3	1891	P12111
PGLSPGDLDVFVRFD	CC2D1A	671	Q6P1N0
LFTAGPLEEERFGFP	BLVRA	151	P53004
PLEEERFGFPAFSGI	BLVRA	156	P53004
ASRPGDEGVPFRFDF	MAN1C1	131	Q9NR34
IDEIFGFFNDGEPPT	FAM118B	11	Q9BPY3
PRLPDDLQDFDFFEG	INO80D	626	Q53TQ3
GGFDFLREDQSSPVP	FRY	1736	Q5TBA9
ASDFEFGVDPSADPE	PSMD4	201	P55036
LEGDPDGQFTIRTDP	CDH15	301	P55291
VLRGTQSFDPDDPGA	PKD1L1	801	Q8TDX9
PFEDLFGQAPGGERD	ECSIT	71	Q9BQ95
DPNDFDFTVTGRGSP	MECP2	151	P51608
GFPRDPSTESGEEEN	RTL1	1021	A6NKG5
GRDSYEENPDFEGIP	RSPH6A	516	Q9H0K4
EREPDPFEFSSGSES	TAF3	401	Q5VWG9
DGADGAFYPDEIQRP	TAX1BP1	646	Q86VP1
DEEEDFFLRGPSGPR	VAMP4	31	O75379
SPESQPGARALFDGD	PRUNE2	2256	Q8WUY3
DGQEDDEILPGFPSF	SYNE1	291	Q8NF91
TDDPLESESGRYQPG	LMBRD2	666	Q68DH5
EREGNSPSFFNPEEA	MOV10	786	Q9HCE1
PEETFPNTETNGEFG	HNRNPK	6	P61978
DLGSGSTRLEFPDFP	LAMA1	2181	P25391
GARGDPAEAADERFP	SOX8	51	P57073
SPGGNDFEIFADPRT	PMM1	221	Q92871
EFEVPFRDLGFNGAP	SUPT16H	796	Q9Y5B9
AEASPTVDSFRPGFD	EXTL1	181	Q92935
FARPGDVEFEDFSQP	TRIP10	276	Q15642
PLGDRIIESFFPDGS	CHP2	61	O43745
FPDGSQRVDFPGFVR	CHP2	71	O43745
QDQGPDSFPDRFRGA	CNGA3	91	Q16281
PPGRPESFAFVDEDE	CLCN1	701	P35523
PGEPGRSFEGSVSFE	ZNF157	16	P51786
GFDPPATDRQFSGAR	YBX3	206	P16989
QGDDFLTPSGLAEPR	VWF	531	P04275
AAVGFEEFSAPPGSE	TFPT	11	P0C1Z6
DGPGEPDVRDGFSAT	PSD2	126	Q9BQI7
FVFGSGINPERDPEI	SESN3	206	P58005
PGRFRDPGSENEFAD	SCN8A	571	Q9UQD0
PFSPDENSLVLFEGD	SEMA7A	171	O75326
AAPRGPEAEFESDSG	SRRD	46	Q9UH36
IPDDFGGRSEDPRDF	TTC14	586	Q96N46
FLPERTSGGPEAADF	RPAP1	1011	Q9BWH6
DDEVSFSQLFPPGGR	ZNF469	2826	Q96JG9
FPGEDLGDPFLQERG	ZNF70	26	Q9UC06
PGTRPQDDELFGQTF	ZNF70	81	Q9UC06
NTAEALPEGFFDDPE	ZNF830	241	Q96NB3
EHRAFGSPFGLEEPQ	ZFYVE21	26	Q9BQ24
GLSESEEAFRAPGPA	TBX4	6	P57082
EEAFRAPGPALGEAS	TBX4	11	P57082
GPEDFGPEENFDASE	WDR33	1126	Q9C0J8
DLVFSSPGDIPAEDF	PTPRH	791	Q9HD43
DPDYPRNISDGFDGI	VTN	236	P04004
FYPEPGAQDADERRG	TBX21	36	Q9UL17
NPFSRVALEFGSEEP	TTF2	886	Q9UNY4
EGRPSAYNFEESPGL	LAMC3	211	Q9Y6N6