Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	microtubule motor activity	DNHD1 SMC3 KIF21A DNAH17 KIF14 KIF5C KIF20B	1.24e-08	70	80	7	GO:0003777
GeneOntologyMolecularFunction	cytoskeletal motor activity	DNHD1 MYO5A SMC3 KIF21A DNAH17 KIF14 KIF5C KIF20B	2.38e-08	118	80	8	GO:0003774
GeneOntologyMolecularFunction	histone modifying activity	KMT2C SLK RNF2 HDAC5 HDAC4 BRCA2 PKN1	3.72e-05	229	80	7	GO:0140993
GeneOntologyMolecularFunction	plus-end-directed microtubule motor activity	KIF14 KIF5C KIF20B	4.04e-05	17	80	3	GO:0008574
GeneOntologyMolecularFunction	RNA polymerase II-specific DNA-binding transcription factor binding	PTPN2 MED30 HDAC5 HDAC4 NKX2-1 PKN1 TP53BP2 SMAD4 HIRA	4.34e-05	417	80	9	GO:0061629
GeneOntologyMolecularFunction	transcription coregulator activity	KMT2C MED30 HDAC5 HDAC4 NKX2-1 MED31 GON4L PKN1 MAML3 HIRA	8.08e-05	562	80	10	GO:0003712
GeneOntologyMolecularFunction	DNA-binding transcription factor binding	PTPN2 MED30 HDAC5 HDAC4 NKX2-1 PKN1 TXLNG TP53BP2 SMAD4 HIRA	1.08e-04	582	80	10	GO:0140297
GeneOntologyMolecularFunction	alkali metal ion binding	HDAC4 SCN1A SCN3A	1.51e-04	26	80	3	GO:0031420
GeneOntologyMolecularFunction	transcription factor binding	PTPN2 MED30 HDAC5 HDAC4 NKX2-1 RORA PKN1 TXLNG TP53BP2 SMAD4 HIRA	1.99e-04	753	80	11	GO:0008134
GeneOntologyMolecularFunction	tubulin binding	BRCA2 SMC3 KIF21A CGN KIF14 DIXDC1 KIF5C KIF20B	3.14e-04	428	80	8	GO:0015631
GeneOntologyMolecularFunction	cytoskeletal protein binding	BRCA2 MYO5A SMC3 KIF21A CGN KIF14 DIXDC1 KIF5C NEB LMOD2 POF1B KIF20B SMAD4	4.01e-04	1099	80	13	GO:0008092
GeneOntologyMolecularFunction	molecular adaptor activity	KMT2C MED30 HDAC5 AKAP9 HDAC4 NKX2-1 ITSN1 MED31 GON4L PKN1 DZIP1 BIN3 MAML3 HIRA	9.10e-04	1356	80	14	GO:0060090
GeneOntologyMolecularFunction	sodium ion binding	SCN1A SCN3A	1.40e-03	14	80	2	GO:0031402
GeneOntologyMolecularFunction	transcription corepressor binding	HDAC5 RORA SMAD4	1.71e-03	59	80	3	GO:0001222
GeneOntologyMolecularFunction	minus-end-directed microtubule motor activity	DNHD1 DNAH17	2.33e-03	18	80	2	GO:0008569
GeneOntologyMolecularFunction	transcription coregulator binding	HDAC5 NKX2-1 RORA SMAD4	2.42e-03	140	80	4	GO:0001221
GeneOntologyMolecularFunction	chromatin binding	TRIM33 RNF2 HDAC5 HDAC4 SMC3 SREBF2 PKN1 SMAD4 HIRA	2.76e-03	739	80	9	GO:0003682
GeneOntologyBiologicalProcess	microtubule-based process	DNHD1 SLK AKAP9 BRCA2 MYO5A SMC3 ODAD1 KIF21A CHMP5 DNAH17 CGN CFAP45 KIF14 DIXDC1 KIF5C DZIP1 CEP97 KIF20B CCDC63	1.25e-08	1058	79	19	GO:0007017
GeneOntologyBiologicalProcess	microtubule-based movement	DNHD1 MYO5A ODAD1 KIF21A DNAH17 CFAP45 KIF14 KIF5C DZIP1 KIF20B CCDC63	2.72e-06	493	79	11	GO:0007018
GeneOntologyBiologicalProcess	microtubule cytoskeleton organization	SLK AKAP9 BRCA2 SMC3 ODAD1 CHMP5 DNAH17 CGN KIF14 DIXDC1 DZIP1 CEP97 CCDC63	3.24e-06	720	79	13	GO:0000226
GeneOntologyBiologicalProcess	negative regulation of striated muscle cell differentiation	SOX6 HDAC5 HDAC4 SMAD4	4.34e-05	51	79	4	GO:0051154
GeneOntologyBiologicalProcess	positive regulation of mesenchymal stem cell differentiation	SOX6 SOX5	8.65e-05	4	79	2	GO:2000741
GeneOntologyBiologicalProcess	outer dynein arm assembly	ODAD1 DNAH17 CCDC63	1.03e-04	24	79	3	GO:0036158
GeneOntologyBiologicalProcess	cytokinesis	BRCA2 CHMP5 EXOC6B KIF14 BIN3 KIF20B	1.33e-04	204	79	6	GO:0000910
GeneOntologyBiologicalProcess	negative regulation of receptor signaling pathway via JAK-STAT	PTPN2 GBP7 INPP5F	1.84e-04	29	79	3	GO:0046426
GeneOntologyBiologicalProcess	muscle cell differentiation	SOX6 HDAC5 HDAC4 RORA NEB BIN3 LMOD2 SMAD4 HIRA	1.93e-04	531	79	9	GO:0042692
GeneOntologyCellularComponent	microtubule associated complex	DNHD1 ODAD1 KIF21A DNAH17 KIF14 KIF5C KIF20B	2.57e-06	161	79	7	GO:0005875
GeneOntologyCellularComponent	kinesin complex	KIF21A KIF14 KIF5C KIF20B	3.52e-05	49	79	4	GO:0005871
GeneOntologyCellularComponent	lateral element	BRCA2 SMC3 SYCP3	4.82e-05	19	79	3	GO:0000800
GeneOntologyCellularComponent	chromatin	SOX6 SOX5 TRIM33 ZNF487 RNF2 HDAC5 HDAC4 SMC3 NKX2-1 SREBF2 GON4L SHOX SYCP3 RORA SMAD4 HIRA	1.12e-04	1480	79	16	GO:0000785
GeneOntologyCellularComponent	axonemal dynein complex	DNHD1 ODAD1 DNAH17	1.13e-04	25	79	3	GO:0005858
GeneOntologyCellularComponent	supramolecular fiber	HDAC4 MYO5A SCN1A KIF21A CHMP5 DNAH17 CFAP45 KIF14 SYNC KIF5C NEB LMOD2 POF1B KIF20B	1.21e-04	1179	79	14	GO:0099512
GeneOntologyCellularComponent	supramolecular polymer	HDAC4 MYO5A SCN1A KIF21A CHMP5 DNAH17 CFAP45 KIF14 SYNC KIF5C NEB LMOD2 POF1B KIF20B	1.30e-04	1187	79	14	GO:0099081
GeneOntologyCellularComponent	host cell part	GBP6 GBP7	2.09e-04	6	79	2	GO:0033643
GeneOntologyCellularComponent	host intracellular part	GBP6 GBP7	2.09e-04	6	79	2	GO:0033646
GeneOntologyCellularComponent	host cell cytoplasm part	GBP6 GBP7	2.09e-04	6	79	2	GO:0033655
GeneOntologyCellularComponent	symbiont-containing vacuole	GBP6 GBP7	2.09e-04	6	79	2	GO:0020003
GeneOntologyCellularComponent	symbiont-containing vacuole membrane	GBP6 GBP7	2.09e-04	6	79	2	GO:0020005
GeneOntologyCellularComponent	host intracellular region	GBP6 GBP7	2.09e-04	6	79	2	GO:0043656
GeneOntologyCellularComponent	host cell cytoplasm	GBP6 GBP7	2.09e-04	6	79	2	GO:0030430
GeneOntologyCellularComponent	actin cytoskeleton	HDAC4 MYO5A ITSN1 CGN DIXDC1 NEB BIN3 LMOD2 POF1B	3.19e-04	576	79	9	GO:0015629
GeneOntologyCellularComponent	cytoplasmic region	DNHD1 ERC1 ODAD1 DNAH17 CFAP45 KIF5C CCDC63	4.24e-04	360	79	7	GO:0099568
GeneOntologyCellularComponent	cilium	DNHD1 AKAP9 MYO5A ERC1 ODAD1 DNAH17 CFAP45 KIF5C DZIP1 CFAP99 CCDC63	5.41e-04	898	79	11	GO:0005929
GeneOntologyCellularComponent	polymeric cytoskeletal fiber	MYO5A KIF21A CHMP5 DNAH17 CFAP45 KIF14 SYNC KIF5C LMOD2 POF1B KIF20B	5.46e-04	899	79	11	GO:0099513
GeneOntologyCellularComponent	synaptonemal complex	BRCA2 SMC3 SYCP3	7.01e-04	46	79	3	GO:0000795
GeneOntologyCellularComponent	synaptonemal structure	BRCA2 SMC3 SYCP3	7.01e-04	46	79	3	GO:0099086
GeneOntologyCellularComponent	outer dynein arm	ODAD1 DNAH17	9.08e-04	12	79	2	GO:0036157
GeneOntologyCellularComponent	dynein complex	DNHD1 ODAD1 DNAH17	1.12e-03	54	79	3	GO:0030286
GeneOntologyCellularComponent	axoneme	DNHD1 ODAD1 DNAH17 CFAP45 CCDC63	1.13e-03	207	79	5	GO:0005930
GeneOntologyCellularComponent	ciliary plasm	DNHD1 ODAD1 DNAH17 CFAP45 CCDC63	1.15e-03	208	79	5	GO:0097014
GeneOntologyCellularComponent	plasma membrane bounded cell projection cytoplasm	DNHD1 ODAD1 DNAH17 CFAP45 KIF5C CCDC63	1.27e-03	317	79	6	GO:0032838
GeneOntologyCellularComponent	host cellular component	GBP6 GBP7	1.43e-03	15	79	2	GO:0018995
GeneOntologyCellularComponent	transcription regulator complex	SOX6 SOX5 MED30 HDAC5 HDAC4 NKX2-1 MED31 SMAD4	1.84e-03	596	79	8	GO:0005667
GeneOntologyCellularComponent	voltage-gated sodium channel complex	SCN1A SCN3A	1.85e-03	17	79	2	GO:0001518
GeneOntologyCellularComponent	axon	HDAC5 MYO5A SCN1A KIF21A ITSN1 SCN3A DIXDC1 KIF5C INPP5F KIF20B	1.89e-03	891	79	10	GO:0030424
GeneOntologyCellularComponent	postsynaptic actin cytoskeleton	MYO5A ITSN1	2.31e-03	19	79	2	GO:0098871
GeneOntologyCellularComponent	centrosome	AKAP9 BRCA2 ERC1 CEP112 DZIP1 HMMR CEP97 KIF20B SMAD4	2.45e-03	770	79	9	GO:0005813
GeneOntologyCellularComponent	sarcomere	HDAC4 SCN1A SYNC NEB LMOD2	2.54e-03	249	79	5	GO:0030017
GeneOntologyCellularComponent	Z disc	HDAC4 SCN1A SYNC NEB	2.58e-03	151	79	4	GO:0030018
GeneOntologyCellularComponent	I band	HDAC4 SCN1A SYNC NEB	3.63e-03	166	79	4	GO:0031674
GeneOntologyCellularComponent	myofibril	HDAC4 SCN1A SYNC NEB LMOD2	3.76e-03	273	79	5	GO:0030016
GeneOntologyCellularComponent	microtubule	KIF21A CHMP5 DNAH17 CFAP45 KIF14 KIF5C KIF20B	4.01e-03	533	79	7	GO:0005874
GeneOntologyCellularComponent	core mediator complex	MED30 MED31	4.32e-03	26	79	2	GO:0070847
GeneOntologyCellularComponent	postsynaptic cytoskeleton	MYO5A ITSN1	4.32e-03	26	79	2	GO:0099571
GeneOntologyCellularComponent	striated muscle thin filament	NEB LMOD2	4.66e-03	27	79	2	GO:0005865
GeneOntologyCellularComponent	contractile muscle fiber	HDAC4 SCN1A SYNC NEB LMOD2	4.85e-03	290	79	5	GO:0043292
GeneOntologyCellularComponent	condensed nuclear chromosome	BRCA2 SMC3 SYCP3	4.97e-03	91	79	3	GO:0000794
GeneOntologyCellularComponent	sodium channel complex	SCN1A SCN3A	5.36e-03	29	79	2	GO:0034706
GeneOntologyCellularComponent	nuclear protein-containing complex	KMT2C MED30 RNF2 HDAC5 SMG7 HDAC4 BRCA2 CHMP5 MED31 GON4L CPSF3 SMAD4	5.37e-03	1377	79	12	GO:0140513
GeneOntologyCellularComponent	distal axon	HDAC5 MYO5A ITSN1 DIXDC1 KIF5C KIF20B	6.07e-03	435	79	6	GO:0150034
GeneOntologyCellularComponent	somatodendritic compartment	AKAP9 MYO5A SCN1A KIF21A ITSN1 SCN3A SREBF2 DIXDC1 KIF5C PALMD INPP5F	6.30e-03	1228	79	11	GO:0036477
GeneOntologyCellularComponent	myofilament	NEB LMOD2	6.50e-03	32	79	2	GO:0036379
GeneOntologyCellularComponent	nuclear body	RNF2 HDAC5 HDAC4 SCN1A GON4L DZIP1 MAML3 HIRA RNF111	6.92e-03	903	79	9	GO:0016604
GeneOntologyCellularComponent	microtubule organizing center	AKAP9 BRCA2 ERC1 CEP112 DZIP1 HMMR CEP97 KIF20B SMAD4	7.73e-03	919	79	9	GO:0005815
MousePheno	abnormal pleural cavity morphology	ANGPT2 NKX2-1	2.47e-05	2	70	2	MP:0012684
MousePheno	abnormal skeletal maturation	PTPN2 DUOX2	7.39e-05	3	70	2	MP:0014294
MousePheno	abnormal ossification involved in bone maturation	PTPN2 DUOX2	7.39e-05	3	70	2	MP:0011722
MousePheno	abnormal thoracic cage morphology	SOX6 SOX5 RNF2 HDAC4 BRCA2 MED31 ANKRD18A ANKRD20A8P ANKRD18B HIRA	9.63e-05	463	70	10	MP:0004624
MousePheno	abnormal abducens nerve morphology	KIF21A TP53BP2	1.47e-04	4	70	2	MP:0001070
MousePheno	abnormal dendrite morphology	MYO5A SMC3 SCN1A KIF14 RORA CADPS2 KIF20B	1.78e-04	237	70	7	MP:0008143
MousePheno	abnormal Purkinje cell dendrite morphology	MYO5A KIF14 RORA CADPS2	1.99e-04	58	70	4	MP:0008572
Domain	Kinesin_motor_CS	KIF21A KIF14 KIF5C KIF20B	2.29e-05	41	76	4	IPR019821
Domain	Kinesin-like_fam	KIF21A KIF14 KIF5C KIF20B	2.77e-05	43	76	4	IPR027640
Domain	KINESIN_MOTOR_1	KIF21A KIF14 KIF5C KIF20B	3.04e-05	44	76	4	PS00411
Domain	-	KIF21A KIF14 KIF5C KIF20B	3.04e-05	44	76	4	3.40.850.10
Domain	Kinesin_motor_dom	KIF21A KIF14 KIF5C KIF20B	3.04e-05	44	76	4	IPR001752
Domain	Kinesin	KIF21A KIF14 KIF5C KIF20B	3.04e-05	44	76	4	PF00225
Domain	KINESIN_MOTOR_2	KIF21A KIF14 KIF5C KIF20B	3.04e-05	44	76	4	PS50067
Domain	KISc	KIF21A KIF14 KIF5C KIF20B	3.04e-05	44	76	4	SM00129
Domain	Hist_deacetylase_Gln_rich_N	HDAC5 HDAC4	4.89e-05	3	76	2	IPR024643
Domain	HDAC4_Gln	HDAC5 HDAC4	4.89e-05	3	76	2	PF12203
Domain	Histone_deAcase_II_euk	HDAC5 HDAC4	9.75e-05	4	76	2	IPR017320
Domain	tRNA-bd_arm	SOX6 SOX5 KIF20B	1.23e-04	24	76	3	IPR010978
Domain	IQ	MYO5A SCN1A SCN3A CEP97	2.00e-04	71	76	4	PF00612
Domain	Na_trans_cytopl	SCN1A SCN3A	2.43e-04	6	76	2	PF11933
Domain	Na_trans_cytopl	SCN1A SCN3A	2.43e-04	6	76	2	IPR024583
Domain	IQ	MYO5A SCN1A SCN3A CEP97	3.32e-04	81	76	4	SM00015
Domain	IQ_motif_EF-hand-BS	MYO5A SCN1A SCN3A CEP97	4.96e-04	90	76	4	IPR000048
Domain	IQ	MYO5A SCN1A SCN3A CEP97	5.62e-04	93	76	4	PS50096
Domain	Na_channel_asu	SCN1A SCN3A	7.20e-04	10	76	2	IPR001696
Domain	Na_trans_assoc	SCN1A SCN3A	7.20e-04	10	76	2	IPR010526
Domain	GBP_C	GBP6 GBP7	7.20e-04	10	76	2	PF02841
Domain	Na_trans_assoc	SCN1A SCN3A	7.20e-04	10	76	2	PF06512
Domain	Hist_deacetyl	HDAC5 HDAC4	8.78e-04	11	76	2	PF00850
Domain	G_GB1_RHD3_dom	GBP6 GBP7	8.78e-04	11	76	2	IPR030386
Domain	Guanylate-bd_C	GBP6 GBP7	8.78e-04	11	76	2	IPR003191
Domain	His_deacetylse_dom	HDAC5 HDAC4	8.78e-04	11	76	2	IPR023801
Domain	GBP	GBP6 GBP7	8.78e-04	11	76	2	PF02263
Domain	-	HDAC5 HDAC4	8.78e-04	11	76	2	3.40.800.20
Domain	His_deacetylse	HDAC5 HDAC4	8.78e-04	11	76	2	IPR000286
Domain	Guanylate-bd_N	GBP6 GBP7	8.78e-04	11	76	2	IPR015894
Domain	G_GB1_RHD3	GBP6 GBP7	8.78e-04	11	76	2	PS51715
Domain	HMG_box	SOX6 SOX5 KMT2C	1.31e-03	53	76	3	PF00505
Domain	HMG	SOX6 SOX5 KMT2C	1.38e-03	54	76	3	SM00398
Domain	HMG_box_dom	SOX6 SOX5 KMT2C	2.36e-03	65	76	3	IPR009071
Domain	EF-hand-dom_pair	SCN1A ITSN1 SCN3A NUCB1 DUOX2	6.29e-03	287	76	5	IPR011992
Domain	P-loop_NTPase	DNHD1 GBP6 GBP7 MYO5A SMC3 KIF21A KIF14 KIF5C KIF20B	7.35e-03	848	76	9	IPR027417
Pubmed	Proteomic and Biochemical Comparison of the Cellular Interaction Partners of Human VPS33A and VPS33B.	NEPRO MIA3 HDAC5 SMG7 ERC1 CHMP5 KIF14 HMMR CEP97	9.50e-09	251	83	9	29778605
Pubmed	SHOX interacts with the chondrogenic transcription factors SOX5 and SOX6 to activate the aggrecan enhancer.	SOX6 SOX5 SHOX	5.23e-08	4	83	3	21262861
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	SLK MIA3 ARHGAP24 AKAP9 HDAC4 MYO5A ERC1 KIF21A ITSN1 PKN1 DIXDC1 KIF5C TP53BP2 HIRA	6.37e-08	963	83	14	28671696
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	MIA3 HDAC5 AKAP9 HDAC4 SMC3 ERC1 CGN KIF14 INPP5F TP53BP2	1.15e-07	446	83	10	24255178
Pubmed	Three brain sodium channel alpha-subunit genes are clustered on the proximal segment of mouse chromosome 2.	SCN1A SCN3A NEB	1.31e-07	5	83	3	1679748
Pubmed	A new sodium channel alpha-subunit gene (Scn9a) from Schwann cells maps to the Scn1a, Scn2a, Scn3a cluster of mouse chromosome 2.	SCN1A SCN3A NEB	1.31e-07	5	83	3	8812438
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	SOX6 TRIM33 MYO5A ERC1 KIF21A ITSN1 NUCB1 MCF2L2 SYNC ANKRD36 KIF5C DZIP1 CADPS2 TXLNG RNF111	3.47e-07	1285	83	15	35914814
Pubmed	Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.	SLK MED30 ERC1 CHMP5 MED31 GON4L KIF14 TXLNG CPSF3 TP53BP2 HIRA	3.95e-07	645	83	11	25281560
Pubmed	Expression of testicular germ cell genes identified by differential display analysis.	ANKRD18A ANKRD20A8P ANKRD18B	7.28e-07	8	83	3	12634303
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	MIA3 SMG7 BRCA2 ERC1 ITSN1 CGN KIF14 KIF5C BIN3 TXLNG CEP97 TP53BP2	8.62e-07	853	83	12	28718761
Pubmed	A human MAP kinase interactome.	KMT2C USF3 HDAC4 SMC3 ITSN1 SREBF2 NEB TXLNG RNF111	2.48e-06	486	83	9	20936779
Pubmed	The variant Polycomb Repressor Complex 1 component PCGF1 interacts with a pluripotency sub-network that includes DPPA4, a regulator of embryogenesis.	RAD52 TRIM33 RNF2 AKAP9 SMC3 ERC1 KIF20B SMAD4	4.93e-06	396	83	8	26687479
Pubmed	Disruption of the Class IIa HDAC Corepressor Complex Increases Energy Expenditure and Lipid Oxidation.	HDAC5 HDAC4	5.63e-06	2	83	2	27626651
Pubmed	Electrophysiological Differences between the Same Pore Region Mutation in SCN1A and SCN3A.	SCN1A SCN3A	5.63e-06	2	83	2	24990319
Pubmed	The RAD52 S346X variant reduces risk of developing breast cancer in carriers of pathogenic germline BRCA2 mutations.	RAD52 BRCA2	5.63e-06	2	83	2	32175645
Pubmed	Nuclear calcium signaling regulates nuclear export of a subset of class IIa histone deacetylases following synaptic activity.	HDAC5 HDAC4	5.63e-06	2	83	2	23364788
Pubmed	Mapping of a FEB3 homologous febrile seizure locus on mouse chromosome 2 containing candidate genes Scn1a and Scn3a.	SCN1A SCN3A	5.63e-06	2	83	2	27690330
Pubmed	Correlations in timing of sodium channel expression, epilepsy, and sudden death in Dravet syndrome.	SCN1A SCN3A	5.63e-06	2	83	2	23965409
Pubmed	Accelerated up-regulation of L-Sox5, Sox6, and Sox9 by BMP-2 gene transfer during murine fracture healing.	SOX6 SOX5	5.63e-06	2	83	2	11585348
Pubmed	Class IIa histone deacetylases link cAMP signaling to the myelin transcriptional program of Schwann cells.	HDAC5 HDAC4	5.63e-06	2	83	2	29472387
Pubmed	RORA gene rs12912233 and rs880626 polymorphisms and their interaction with SCN1A rs3812718 in the risk of epilepsy: a case-control study in Malaysia.	SCN1A RORA	5.63e-06	2	83	2	25668517
Pubmed	Histone deacetylase 4 mediates SMAD family member 4 deacetylation and induces 5-fluorouracil resistance in breast cancer cells.	HDAC4 SMAD4	5.63e-06	2	83	2	23817620
Pubmed	Generation of mice harboring a Sox5 conditional null allele.	SOX6 SOX5	5.63e-06	2	83	2	18543318
Pubmed	TIF1γ and SMAD4 regulation in colorectal cancer: impact on cell proliferation and liver metastasis.	TRIM33 SMAD4	5.63e-06	2	83	2	38270141
Pubmed	Nitric oxide modulates chromatin folding in human endothelial cells via protein phosphatase 2A activation and class II histone deacetylases nuclear shuttling.	HDAC5 HDAC4	5.63e-06	2	83	2	17975112
Pubmed	Rad52 inactivation is synthetically lethal with BRCA2 deficiency.	RAD52 BRCA2	5.63e-06	2	83	2	21148102
Pubmed	Human RAD52 protein regulates homologous recombination and checkpoint function in BRCA2 deficient cells.	RAD52 BRCA2	5.63e-06	2	83	2	30590106
Pubmed	Class IIa HDACs regulate learning and memory through dynamic experience-dependent repression of transcription.	HDAC5 HDAC4	5.63e-06	2	83	2	31375688
Pubmed	Class II histone deacetylases downregulate GLUT4 transcription in response to increased cAMP signaling in cultured adipocytes and fasting mice.	HDAC5 HDAC4	5.63e-06	2	83	2	22403301
Pubmed	Germ-layer specification and control of cell growth by Ectodermin, a Smad4 ubiquitin ligase.	TRIM33 SMAD4	5.63e-06	2	83	2	15820681
Pubmed	Control of cardiac growth by histone acetylation/deacetylation.	HDAC5 HDAC4	5.63e-06	2	83	2	16397154
Pubmed	Insilico study of genes involved in Congenital Hypothyroidism.	NKX2-1 DUOX2	5.63e-06	2	83	2	32207419
Pubmed	A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.	SLK RNF2 SMG7 CELF1 MYO5A ERC1 CHMP5 HMMR TXLNG HIRA	8.90e-06	724	83	10	36232890
Pubmed	Intracellular biosynthesis of lipids and cholesterol by Scap and Insig in mesenchymal cells regulates long bone growth and chondrocyte homeostasis.	SOX6 SOX5 SREBF2	1.04e-05	18	83	3	29899135
Pubmed	DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity.	RAD52 TRIM33 MED30 BRCA2 CHMP5 MED31 KIF20B HIRA	1.31e-05	453	83	8	29656893
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	RNF2 HDAC5 HDAC4 SMC3 ERC1 CGN EXOC6B CCDC150 KIF5C HMMR TXLNG CEP97 TP53BP2	1.44e-05	1321	83	13	27173435
Pubmed	SoxD genes are required for adult neural stem cell activation.	SOX6 SOX5	1.69e-05	3	83	2	35108528
Pubmed	Mutations in the sodium channel genes SCN1A, SCN3A, and SCN9A in children with epilepsy with febrile seizures plus(EFS+).	SCN1A SCN3A	1.69e-05	3	83	2	33895391
Pubmed	SCN1A, SCN2A and SCN3A gene polymorphisms and responsiveness to antiepileptic drugs: a multicenter cohort study and meta-analysis.	SCN1A SCN3A	1.69e-05	3	83	2	23859570
Pubmed	The orphan nuclear receptor ROR alpha (RORA) maps to a conserved region of homology on human chromosome 15q21-q22 and mouse chromosome 9.	MYO5A RORA	1.69e-05	3	83	2	7490103
Pubmed	Antagonistic regulation of EMT by TIF1γ and Smad4 in mammary epithelial cells.	TRIM33 SMAD4	1.69e-05	3	83	2	21597466
Pubmed	Identification of a signal-responsive nuclear export sequence in class II histone deacetylases.	HDAC5 HDAC4	1.69e-05	3	83	2	11509672
Pubmed	GAPDH-mediated posttranscriptional regulations of sodium channel Scn1a and Scn3a genes under seizure and ketogenic diet conditions.	SCN1A SCN3A	1.69e-05	3	83	2	27816501
Pubmed	Recruitment of TIF1γ to chromatin via its PHD finger-bromodomain activates its ubiquitin ligase and transcriptional repressor activities.	TRIM33 SMAD4	1.69e-05	3	83	2	21726812
Pubmed	Sodium channels SCN1A, SCN2A and SCN3A in familial autism.	SCN1A SCN3A	1.69e-05	3	83	2	12610651
Pubmed	NOX2-dependent ROS is required for HDAC5 nuclear efflux and contributes to HDAC4 nuclear efflux during intense repetitive activity of fast skeletal muscle fibers.	HDAC5 HDAC4	1.69e-05	3	83	2	22648949
Pubmed	Cohesin SMC1beta protects telomeres in meiocytes.	SMC3 SYCP3	1.69e-05	3	83	2	19841137
Pubmed	Multidrug resistance in epilepsy and polymorphisms in the voltage-gated sodium channel genes SCN1A, SCN2A, and SCN3A: correlation among phenotype, genotype, and mRNA expression.	SCN1A SCN3A	1.69e-05	3	83	2	18784617
Pubmed	The transcription factors SOX9 and SOX5/SOX6 cooperate genome-wide through super-enhancers to drive chondrogenesis.	SOX6 SOX5	1.69e-05	3	83	2	26150426
Pubmed	Tif1γ is essential for the terminal differentiation of mammary alveolar epithelial cells and for lactation through SMAD4 inhibition.	TRIM33 SMAD4	1.69e-05	3	83	2	23154409
Pubmed	Characterization of 5' untranslated regions of the voltage-gated sodium channels SCN1A, SCN2A, and SCN3A and identification of cis-conserved noncoding sequences.	SCN1A SCN3A	1.69e-05	3	83	2	17544618
Pubmed	G betagamma binds histone deacetylase 5 (HDAC5) and inhibits its transcriptional co-repression activity.	HDAC5 HDAC4	1.69e-05	3	83	2	16221676
Pubmed	Tif1γ suppresses murine pancreatic tumoral transformation by a Smad4-independent pathway.	TRIM33 SMAD4	1.69e-05	3	83	2	22469842
Pubmed	DSS1 interacts with and stimulates RAD52 to promote the repair of DSBs.	RAD52 BRCA2	1.69e-05	3	83	2	31799622
Pubmed	Neddylation Regulates Class IIa and III Histone Deacetylases to Mediate Myoblast Differentiation.	HDAC5 HDAC4	1.69e-05	3	83	2	34502418
Pubmed	Histone deacetylase 5 is a phosphorylation substrate of protein kinase D in osteoclasts.	HDAC5 HDAC4	1.69e-05	3	83	2	35318161
Pubmed	Generation of mice harboring a Sox6 conditional null allele.	SOX6 SOX5	1.69e-05	3	83	2	16652367
Pubmed	Dephosphorylation at a conserved SP motif governs cAMP sensitivity and nuclear localization of class IIa histone deacetylases.	HDAC5 HDAC4	1.69e-05	3	83	2	23297420
Pubmed	SMAD4, activated by the TCR-triggered MEK/ERK signaling pathway, critically regulates CD8+ T cell cytotoxic function.	TRIM33 SMAD4	1.69e-05	3	83	2	35895826
Pubmed	A FAK/HDAC5 signaling axis controls osteocyte mechanotransduction.	HDAC5 HDAC4	1.69e-05	3	83	2	32612176
Pubmed	The small heat-shock protein αB-crystallin is essential for the nuclear localization of Smad4: impact on pulmonary fibrosis.	TRIM33 SMAD4	1.69e-05	3	83	2	24307592
Pubmed	The combination of SOX5, SOX6, and SOX9 (the SOX trio) provides signals sufficient for induction of permanent cartilage.	SOX6 SOX5	1.69e-05	3	83	2	15529345
Pubmed	cDNA cloning, expression analysis, and mapping of the mouse Nedd4 gene.	MYO5A RORA	1.69e-05	3	83	2	9073511
Pubmed	SOX trio decrease in the articular cartilage with the advancement of osteoarthritis.	SOX6 SOX5	1.69e-05	3	83	2	21728837
Pubmed	Early expression of sodium channel transcripts and sodium current by cajal-retzius cells in the preplate of the embryonic mouse neocortex.	SCN1A SCN3A	1.69e-05	3	83	2	14973256
Pubmed	SOX5/6/21 Prevent Oncogene-Driven Transformation of Brain Stem Cells.	SOX6 SOX5	1.69e-05	3	83	2	28687615
Pubmed	Electroporation-mediated transfer of SOX trio genes (SOX-5, SOX-6, and SOX-9) to enhance the chondrogenesis of mesenchymal stem cells.	SOX6 SOX5	1.69e-05	3	83	2	21401405
Pubmed	Synaptonemal complex protein SYCP3 impairs mitotic recombination by interfering with BRCA2.	BRCA2 SYCP3	1.69e-05	3	83	2	22116401
Pubmed	Multiple roles and interactions of Tbx4 and Tbx5 in development of the respiratory system.	SOX6 SOX5 NKX2-1	1.69e-05	21	83	3	22876201
Pubmed	A direct physical interaction between Nanog and Sox2 regulates embryonic stem cell self-renewal.	KMT2C RNF2 BRCA2 SMC3 HIRA	2.72e-05	146	83	5	23892456
Pubmed	The C. elegans homolog of human panic-disorder risk gene TMEM132D orchestrates neuronal morphogenesis through the WAVE-regulatory complex.	PTPN2 RNF2 ANKRD36 CADPS2	2.74e-05	72	83	4	33726789
Pubmed	Human transcription factor protein interaction networks.	SOX6 SOX5 TRIM33 KMT2C NEPRO SLK RNF2 HDAC5 SMG7 MYO5A SMC3 GON4L HIRA	3.27e-05	1429	83	13	35140242
Pubmed	Molecular mechanism of transcriptional repression of AhR repressor involving ANKRA2, HDAC4, and HDAC5.	HDAC5 HDAC4	3.37e-05	4	83	2	17949687
Pubmed	Rad52 gene mutations in breast/ovarian cancer families and sporadic ovarian carcinoma patients.	RAD52 BRCA2	3.37e-05	4	83	2	12883740
Pubmed	Nav1.1 localizes to axons of parvalbumin-positive inhibitory interneurons: a circuit basis for epileptic seizures in mice carrying an Scn1a gene mutation.	SCN1A SCN3A	3.37e-05	4	83	2	17537961
Pubmed	L-Sox5 and Sox6 drive expression of the aggrecan gene in cartilage by securing binding of Sox9 to a far-upstream enhancer.	SOX6 SOX5	3.37e-05	4	83	2	18559420
Pubmed	Sterol response element binding protein and thyroid transcription factor-1 (Nkx2.1) regulate Abca3 gene expression.	NKX2-1 SREBF2	3.37e-05	4	83	2	17890326
Pubmed	miR-23a-3p regulated by LncRNA SNHG5 suppresses the chondrogenic differentiation of human adipose-derived stem cells via targeting SOX6/SOX5.	SOX6 SOX5	3.37e-05	4	83	2	32960357
Pubmed	Up-regulation of HO-1 promotes resistance of B-cell acute lymphocytic leukemia cells to HDAC4/5 inhibitor LMK-235 via the Smad7 pathway.	HDAC5 HDAC4	3.37e-05	4	83	2	29886060
Pubmed	SIK1 is a class II HDAC kinase that promotes survival of skeletal myocytes.	HDAC5 HDAC4	3.37e-05	4	83	2	17468767
Pubmed	Dynamic epigenetic mechanisms regulate age-dependent SOX9 expression in mouse articular cartilage.	SOX6 SOX5	3.37e-05	4	83	2	26806292
Pubmed	RAD52 aptamer regulates DNA damage repair and STAT3 in BRCA1/BRCA2‑deficient human acute myeloid leukemia.	RAD52 BRCA2	3.37e-05	4	83	2	32945515
Pubmed	SIKs control osteocyte responses to parathyroid hormone.	HDAC5 HDAC4	3.37e-05	4	83	2	27759007
Pubmed	mHDA1/HDAC5 histone deacetylase interacts with and represses MEF2A transcriptional activity.	HDAC5 HDAC4	3.37e-05	4	83	2	10748098
Pubmed	Trim33 mediates the proinflammatory function of Th17 cells.	TRIM33 SMAD4	3.37e-05	4	83	2	29930104
Pubmed	Association of sodium voltage-gated channel genes polymorphisms with epilepsy risk and prognosis in the Saudi population.	SCN1A SCN3A	3.37e-05	4	83	2	35801810
Pubmed	Class II HDACs mediate CaMK-dependent signaling to NRSF in ventricular myocytes.	HDAC5 HDAC4	3.37e-05	4	83	2	17011572
Pubmed	Dynamic regulation of Tgf-B signaling by Tif1γ: a computational approach.	TRIM33 SMAD4	3.37e-05	4	83	2	22461896
Pubmed	Sodium channel expression and transcript variation in the developing brain of human, Rhesus monkey, and mouse.	SCN1A SCN3A	3.37e-05	4	83	2	35031483
Pubmed	Abnormal changes in voltage-gated sodium channels subtypes NaV1.1, NaV1.2, NaV1.3, NaV1.6 and CaM/CaMKII pathway in low-grade astrocytoma.	SCN1A SCN3A	3.37e-05	4	83	2	29578003
Pubmed	Exercise-induced GLUT4 transcription via inactivation of HDAC4/5 in mouse skeletal muscle in an AMPKα2-dependent manner.	HDAC5 HDAC4	3.37e-05	4	83	2	28688716
Pubmed	The structural integrity of ROR alpha isoforms is mutated in staggerer mice: cerebellar coexpression of ROR alpha1 and ROR alpha4.	MYO5A RORA	3.37e-05	4	83	2	9226375
Pubmed	Timeless Maintains Genomic Stability and Suppresses Sister Chromatid Exchange during Unperturbed DNA Replication.	RAD52 BRCA2	3.37e-05	4	83	2	19112184
Pubmed	PTHrP targets HDAC4 and HDAC5 to repress chondrocyte hypertrophy.	HDAC5 HDAC4	3.37e-05	4	83	2	30843886
Pubmed	Class IIa histone deacetylases: conducting development and differentiation.	HDAC5 HDAC4	3.37e-05	4	83	2	19412888
Pubmed	Sox9 family members negatively regulate maturation and calcification of chondrocytes through up-regulation of parathyroid hormone-related protein.	SOX6 SOX5	3.37e-05	4	83	2	19759178
Pubmed	HDAC4 and 5 repression of TBX5 is relieved by protein kinase D1.	HDAC5 HDAC4	3.37e-05	4	83	2	31784580
Pubmed	Use of recombinant inbred strains for studying genetic determinants of responses to alcohol.	SCN1A SCN3A	3.37e-05	4	83	2	8974318
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	RNF2 MYO5A ERC1 CEP112 KIF21A ITSN1 NUCB1 CFAP45 CCDC150 DUOX2 KIF5C NEB CADPS2	3.59e-05	1442	83	13	35575683
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	AKAP9 HDAC4 ERC1 CEP112 CGN KIF14 KIF5C DZIP1 INPP5F TP53BP2	3.91e-05	861	83	10	36931259
Interaction	CEP135 interactions	MIA3 AKAP9 SMG7 BRCA2 ERC1 CEP112 CGN SREBF2 KIF14 TXLNG CEP97 KIF20B TP53BP2	6.14e-11	272	81	13	int:CEP135
Interaction	PCM1 interactions	HDAC5 AKAP9 SMG7 HDAC4 ERC1 CEP112 SREBF2 KIF14 HMMR BIN3 TXLNG CEP97 TP53BP2	1.78e-08	434	81	13	int:PCM1
Interaction	HNRNPUL1 interactions	SOX6 TRIM33 ARHGAP24 RNF2 SMG7 CELF1 NKX2-1 MED31 KIF14 TP53BP2	1.42e-06	351	81	10	int:HNRNPUL1
Interaction	H2BC9 interactions	USF3 ARHGAP24 MED30 SMC3 DUOX2 ANKRD36 HMMR NEB MAML3 TP53BP2 CCDC63	1.66e-06	446	81	11	int:H2BC9
Interaction	NIN interactions	TRIM33 MIA3 SMG7 BRCA2 ERC1 KIF14 HMMR TXLNG CEP97 TP53BP2	1.74e-06	359	81	10	int:NIN
Interaction	CAPRIN1 interactions	SOX6 SOX5 TRIM33 NEPRO RNF2 SMG7 CELF1 CFAP45 KIF14 ANKRD36 CPSF3	1.85e-06	451	81	11	int:CAPRIN1
Interaction	NANOG interactions	RAD52 TRIM33 KMT2C RNF2 AKAP9 BRCA2 SMC3 ERC1 KIF20B SMAD4 HIRA	3.44e-06	481	81	11	int:NANOG
Interaction	NDC80 interactions	MIA3 AKAP9 ERC1 KIF14 SYNC HMMR TXLNG CEP97 TP53BP2	4.47e-06	312	81	9	int:NDC80
Interaction	EGR2 interactions	SOX5 TRIM33 KMT2C HDAC5 HDAC4 MED31 HIRA	5.74e-06	171	81	7	int:EGR2
Interaction	H2BC12 interactions	TRIM33 ARHGAP24 HDAC5 SMC3 KIF14 DUOX2 ANKRD36 NEB HIRA	5.77e-06	322	81	9	int:H2BC12
Interaction	PFN1 interactions	RAD52 ARHGAP24 HDAC5 AKAP9 SMG7 MYO5A ERC1 ITSN1 KIF14 INPP5F CEP97	5.89e-06	509	81	11	int:PFN1
Interaction	DNAJC10 interactions	TRIM33 PTPN2 MIA3 ARHGAP24 AKAP9 HDAC4 NUCB1 KIF14	9.83e-06	260	81	8	int:DNAJC10
Interaction	MED4 interactions	SLK MED30 RNF2 ERC1 ITSN1 MED31 KIF14 TXLNG CPSF3 TP53BP2	1.27e-05	450	81	10	int:MED4
Interaction	ULK2 interactions	SREBF2 KIF14 DIXDC1 KIF20B	1.45e-05	37	81	4	int:ULK2
Interaction	HNF4A interactions	TRIM33 KMT2C HDAC5 HDAC4 SMC3 SREBF2 SMAD4 HIRA	1.48e-05	275	81	8	int:HNF4A
Interaction	SFN interactions	PTPN2 SLK HDAC5 AKAP9 HDAC4 CEP112 CGN KIF14 INPP5F NEB POF1B TP53BP2	1.97e-05	692	81	12	int:SFN
Interaction	SUMO1 interactions	SOX6 RAD52 AKAP9 HDAC4 SREBF2 KIF14 SMAD4 RNF111	2.01e-05	287	81	8	int:SUMO1
Interaction	KDM1A interactions	SOX6 RNF2 HDAC5 AKAP9 SMG7 BRCA2 NKX2-1 ERC1 CCDC74A KIF14 INPP5F KIF20B TP53BP2 SMAD4	2.09e-05	941	81	14	int:KDM1A
Interaction	MEF2D interactions	SOX6 HDAC5 SMG7 HDAC4 HIRA	2.64e-05	87	81	5	int:MEF2D
Interaction	AMOT interactions	MIA3 ARHGAP24 SMG7 ERC1 CGN KIF14 CEP97 TP53BP2	3.64e-05	312	81	8	int:AMOT
Interaction	SMC3 interactions	TRIM33 RNF2 HDAC5 AKAP9 BRCA2 SMC3 KIF14 SYCP3 RORA	3.77e-05	408	81	9	int:SMC3
Interaction	DBN1 interactions	SOX5 PTPN2 ARHGAP24 MYO5A SMC3 CGN KIF14 DIXDC1 PALMD	4.46e-05	417	81	9	int:DBN1
Interaction	NEFL interactions	ARHGAP24 MYO5A ITSN1 KIF14 PKN1 SYNC	4.69e-05	161	81	6	int:NEFL
Interaction	YWHAB interactions	TRIM33 SLK HDAC5 AKAP9 HDAC4 ERC1 CEP112 CGN KIF14 KIF5C DZIP1 INPP5F NEB TP53BP2	4.74e-05	1014	81	14	int:YWHAB
Interaction	KRT37 interactions	TRIM33 ERC1 PKN1 ANKRD36 TXLNG	5.17e-05	100	81	5	int:KRT37
Interaction	HMG20A interactions	SOX6 SOX5 RNF2 SMG7 GON4L HMMR SMAD4	5.68e-05	244	81	7	int:HMG20A
Interaction	UBE2I interactions	SOX6 SOX5 RAD52 TRIM33 HDAC5 HDAC4 NKX2-1 SREBF2 SMAD4 HIRA RNF111	5.95e-05	654	81	11	int:UBE2I
Interaction	CAMSAP2 interactions	AKAP9 HDAC4 CELF1 CGN KIF14 HMMR	6.14e-05	169	81	6	int:CAMSAP2
Interaction	KRT38 interactions	TRIM33 HDAC4 BRCA2 ERC1 TXLNG CEP97	6.77e-05	172	81	6	int:KRT38
Interaction	H1-2 interactions	NEPRO GBP6 USF3 ARHGAP24 RNF2 HDAC5 HDAC4 KIF14 NEB KIF20B TP53BP2	7.01e-05	666	81	11	int:H1-2
Interaction	PHF21A interactions	RNF2 HDAC5 BRCA2 ERC1 KIF14 INPP5F KIF20B TP53BP2	7.09e-05	343	81	8	int:PHF21A
Interaction	RBM33 interactions	SOX6 SOX5 SMG7 CELF1 KIF14	1.09e-04	117	81	5	int:RBM33
Interaction	HDAC1 interactions	SOX6 RNF2 HDAC5 AKAP9 BRCA2 SMC3 NKX2-1 ERC1 GON4L KIF14 INPP5F KIF20B TP53BP2 SMAD4	1.22e-04	1108	81	14	int:HDAC1
Interaction	CALM1 interactions	TRIM33 RNF2 AKAP9 HDAC4 MYO5A SCN1A KIF14 HMMR NEB CEP97	2.01e-04	626	81	10	int:CALM1
Interaction	YWHAZ interactions	RAD52 SLK HDAC5 AKAP9 HDAC4 MYO5A ERC1 CEP112 CGN KIF14 KIF5C DZIP1 INPP5F NEB TP53BP2	2.17e-04	1319	81	15	int:YWHAZ
Interaction	UACA interactions	TRIM33 RNF2 NUCB1 KIF14 SYNC	2.21e-04	136	81	5	int:UACA
Interaction	TMEM132D interactions	PTPN2 RNF2 ANKRD36 CADPS2	2.25e-04	74	81	4	int:TMEM132D
Interaction	TBL1X interactions	SOX6 SOX5 TRIM33 HDAC5 HDAC4	2.36e-04	138	81	5	int:TBL1X
Interaction	MEF2A interactions	HDAC5 HDAC4 SMAD4 HIRA	2.49e-04	76	81	4	int:MEF2A
Interaction	AKAP9 interactions	RNF2 AKAP9 MYO5A SMC3 KIF14 PKN1	2.66e-04	221	81	6	int:AKAP9
Interaction	KIF13B interactions	TRIM33 RNF2 HDAC5 HDAC4 CGN	2.70e-04	142	81	5	int:KIF13B
Interaction	SMC1A interactions	RNF2 HDAC5 BRCA2 SMC3 ITSN1 KIF14 SYCP3 RORA	2.75e-04	418	81	8	int:SMC1A
Interaction	ERG interactions	SOX6 TRIM33 KMT2C RNF2 MYO5A RNF111	2.79e-04	223	81	6	int:ERG
Interaction	IMPDH2 interactions	SLK HDAC5 AKAP9 NKX2-1 ERC1 KIF21A KIF14 CPSF3	2.84e-04	420	81	8	int:IMPDH2
Interaction	POLR2A interactions	RAD52 MED30 RNF2 HDAC4 BRCA2 SMC3 MED31 CPSF3 HIRA	2.97e-04	536	81	9	int:POLR2A
Interaction	MEGF10 interactions	HDAC4 MCF2L2 CADPS2	3.13e-04	33	81	3	int:MEGF10
Interaction	ELF5 interactions	TRIM33 KMT2C MYO5A SMC3 HIRA	3.17e-04	147	81	5	int:ELF5
Interaction	KPNB1 interactions	PTPN2 ARHGAP24 HDAC5 SMC3 NKX2-1 SREBF2 KIF14 KIF20B SMAD4	3.31e-04	544	81	9	int:KPNB1
Interaction	AHRR interactions	HDAC5 HDAC4	3.31e-04	7	81	2	int:AHRR
Interaction	SYCP2 interactions	SMC3 SYCP3	3.31e-04	7	81	2	int:SYCP2
Interaction	TBX5 interactions	TRIM33 RNF2 CHMP5 MED31 KIF20B	3.47e-04	150	81	5	int:TBX5
Interaction	ATAD3A interactions	SOX6 SOX5 ARHGAP24 RNF2 SREBF2 KIF14 NEB	3.65e-04	330	81	7	int:ATAD3A
Interaction	CGN interactions	HDAC5 HDAC4 CGN KIF14 TP53BP2	3.69e-04	152	81	5	int:CGN
Interaction	GFAP interactions	MYO5A ITSN1 KIF14 RORA SYNC TP53BP2	3.78e-04	236	81	6	int:GFAP
Interaction	PXN interactions	MIA3 AKAP9 SMG7 ERC1 CHMP5 KIF14 CEP97	3.92e-04	334	81	7	int:PXN
Interaction	DYDC1 interactions	HDAC4 BRCA2 PKN1	4.06e-04	36	81	3	int:DYDC1
Interaction	CYTH3 interactions	ODAD1 ITSN1 KIF14	4.06e-04	36	81	3	int:CYTH3
Interaction	SYNE3 interactions	MIA3 SMG7 BRCA2 ERC1 NUCB1 KIF14 CEP97 TP53BP2	4.11e-04	444	81	8	int:SYNE3
Interaction	YWHAG interactions	SLK HDAC5 AKAP9 HDAC4 ERC1 CEP112 CGN KIF14 KIF5C DZIP1 INPP5F CPSF3 CEP97 TP53BP2	4.16e-04	1248	81	14	int:YWHAG
Interaction	PRR12 interactions	SMG7 HDAC4 SMC3 KIF14	4.37e-04	88	81	4	int:PRR12
Interaction	GBP7 interactions	GBP6 GBP7	4.40e-04	8	81	2	int:GBP7
Interaction	ODF2 interactions	SMG7 ODAD1 KIF14 CEP97 TP53BP2	4.41e-04	158	81	5	int:ODF2
Interaction	DES interactions	ERC1 ITSN1 KIF14 SYNC NEB	4.41e-04	158	81	5	int:DES
Interaction	PSMC6 interactions	PTPN2 HDAC5 HDAC4 CHMP5 CCDC74A SREBF2 KIF14	4.52e-04	342	81	7	int:PSMC6
Interaction	CEP104 interactions	ERC1 KIF14 CEP97 TP53BP2	4.56e-04	89	81	4	int:CEP104
Interaction	YWHAQ interactions	SLK HDAC5 HDAC4 ERC1 CEP112 CGN KIF14 ANKRD18A KIF5C DZIP1 INPP5F NEB TP53BP2	4.89e-04	1118	81	13	int:YWHAQ
Interaction	ENO1 interactions	RAD52 ARHGAP24 HDAC5 HDAC4 SMC3 KIF14 KIF5C NEB TXLNG ANKRD18B	4.93e-04	701	81	10	int:ENO1
Interaction	G3BP1 interactions	SOX6 SOX5 PTPN2 ARHGAP24 RNF2 SMG7 CELF1 KIF14 SYCP3 CPSF3 POF1B	4.96e-04	835	81	11	int:G3BP1
Interaction	KIF5B interactions	TRIM33 SLK ARHGAP24 HDAC4 MYO5A KIF14 KIF5C	5.01e-04	348	81	7	int:KIF5B
Interaction	ASF1A interactions	SOX6 TRIM33 HDAC4 BRCA2 KIF20B HIRA	5.01e-04	249	81	6	int:ASF1A
Interaction	NINL interactions	SMG7 BRCA2 MYO5A ERC1 KIF14 TXLNG CEP97 TP53BP2	5.05e-04	458	81	8	int:NINL
Interaction	RBMX interactions	TRIM33 SLK RNF2 HDAC5 CELF1 BRCA2 NKX2-1 KIF14	5.27e-04	461	81	8	int:RBMX
Interaction	UPF1 interactions	TRIM33 RNF2 HDAC5 SMG7 HDAC4 CELF1 BRCA2 KIF14 HIRA	5.33e-04	581	81	9	int:UPF1
Interaction	LHX4 interactions	TRIM33 KMT2C CEP97 TP53BP2 SMAD4	5.52e-04	166	81	5	int:LHX4
Interaction	DCP1A interactions	RAD52 TRIM33 SMG7 HDAC4 SMAD4	5.52e-04	166	81	5	int:DCP1A
Interaction	CEP55 interactions	MIA3 AKAP9 ODAD1 KIF14 SYNC TP53BP2	5.80e-04	256	81	6	int:CEP55
Interaction	CEP162 interactions	ERC1 KIF14 TXLNG CEP97 TP53BP2	5.83e-04	168	81	5	int:CEP162
Interaction	MECOM interactions	SOX6 SMG7 HDAC4 SMC3 DZIP1 NEB SMAD4	5.93e-04	358	81	7	int:MECOM
Interaction	ZNF521 interactions	SOX6 SOX5 SMAD4	5.97e-04	41	81	3	int:ZNF521
Interaction	INSYN1 interactions	MED30 ERC1 PKN1 KIF5C HMMR	5.99e-04	169	81	5	int:INSYN1
Interaction	CDC5L interactions	SLK RNF2 HDAC5 AKAP9 HDAC4 SMC3 KIF21A KIF14 DIXDC1 CPSF3 TP53BP2	6.04e-04	855	81	11	int:CDC5L
Interaction	JDP2 interactions	HDAC5 HDAC4 NKX2-1	6.41e-04	42	81	3	int:JDP2
Interaction	NCOR1 interactions	SOX6 SOX5 TRIM33 HDAC5 SMG7 HDAC4 SMAD4	6.44e-04	363	81	7	int:NCOR1
Interaction	NEMF interactions	HDAC4 ITSN1 ANKRD18A SMAD4	6.57e-04	98	81	4	int:NEMF
Interaction	SP1 interactions	NEPRO HDAC4 BRCA2 SREBF2 RORA NEB SMAD4	6.65e-04	365	81	7	int:SP1
Interaction	USP7 interactions	SOX6 DNHD1 TRIM33 RNF2 HDAC5 MYO5A CEP112 SCN3A NUCB1 CFAP45 SREBF2 GON4L NEB SMAD4	6.90e-04	1313	81	14	int:USP7
Interaction	RDM1 interactions	RAD52 BRCA2	7.03e-04	10	81	2	int:RDM1
Interaction	PSMC5 interactions	PTPN2 SLK HDAC5 CHMP5 CCDC74A KIF14 RORA ANKRD36	7.24e-04	484	81	8	int:PSMC5
Interaction	ABTB2 interactions	SMG7 KIF14 NEB CEP97	7.36e-04	101	81	4	int:ABTB2
Interaction	FBXL13 interactions	BRCA2 CGN NEB	7.36e-04	44	81	3	int:FBXL13
Interaction	NUP93 interactions	ARHGAP24 RNF2 HDAC5 NKX2-1 ITSN1 KIF14	7.52e-04	269	81	6	int:NUP93
Interaction	KHDRBS1 interactions	ARHGAP24 RNF2 HDAC4 CELF1 ITSN1 KIF14 HMMR	7.55e-04	373	81	7	int:KHDRBS1
Cytoband	15q21	MYO5A RNF111	1.76e-04	11	83	2	15q21
GeneFamily	Kinesins\|Pleckstrin homology domain containing	KIF21A KIF14 KIF5C KIF20B	9.80e-06	46	53	4	622
GeneFamily	Histone deacetylases, class IIA	HDAC5 HDAC4	5.04e-05	4	53	2	992
GeneFamily	Sodium voltage-gated channel alpha subunits	SCN1A SCN3A	3.00e-04	9	53	2	1203
GeneFamily	SRY-boxes	SOX6 SOX5	1.40e-03	19	53	2	757
GeneFamily	Cyclins\|Mediator complex	MED30 MED31	4.20e-03	33	53	2	1061
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	ITSN1 CADPS2	4.98e-03	36	53	2	823
GeneFamily	Ankyrin repeat domain containing	ANKRD18A ANKRD36 ANKRD18B TP53BP2	5.49e-03	242	53	4	403
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	TRIM33 PTPN2 SLK RNF2 AKAP9 HDAC4 BRCA2 SMC3 ERC1 ITSN1 KIF14 KIF5C HMMR INPP5F KIF20B TP53BP2 SMAD4 HIRA	1.52e-10	856	83	18	M4500
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN	TRIM33 PTPN2 SLK AKAP9 ITSN1 KIF14 KIF5C INPP5F KIF20B TP53BP2 HIRA	2.55e-07	466	83	11	M13522
Coexpression	GSE5142_CTRL_VS_HTERT_TRANSDUCED_CD8_TCELL_EARLY_PASSAGE_CLONE_UP	SLK GBP7 MYO5A RORA KIF5C INPP5F KIF20B	3.45e-06	200	83	7	M6549
Coexpression	BLANCO_MELO_SARS_COV_1_INFECTION_MCR5_CELLS_UP	BRCA2 KIF14 KIF20B	6.60e-06	12	83	3	M34000
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HGABA	MIA3 ARHGAP24 AKAP9 CELF1 MYO5A SCN1A KIF21A SCN3A CGN RORA ANKRD18A ANKRD36 KIF5C NEB	9.11e-06	1106	83	14	M39071
Coexpression	HAMAI_APOPTOSIS_VIA_TRAIL_UP	TRIM33 SLK MYO5A SMC3 CEP112 KIF14 RORA DZIP1 HMMR KIF20B	4.24e-05	656	83	10	M18979
Coexpression	GSE37532_WT_VS_PPARG_KO_LN_TCONV_UP	KMT2C GBP6 RNF2 INPP5F CEP97 RNF111	4.24e-05	200	83	6	M8954
Coexpression	BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_UP	TRIM33 SLK HDAC5 AKAP9 CELF1 CEP112 GON4L SYNC IP6K2 TP53BP2 SMAD4	5.57e-05	822	83	11	M6782
Coexpression	LAKE_ADULT_KIDNEY_C2_PODOCYTES	SOX6 SLK ERC1 CEP112 ANKRD36 MAML3	5.86e-05	212	83	6	M39221
CoexpressionAtlas	FacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_2500_k-means-cluster#5	TRIM33 PTPN2 SLK RNF2 AKAP9 BRCA2 SMC3 KIF21A KIF5C MAML3 KIF20B	2.32e-05	629	80	11	Facebase_RNAseq_e10.5_Maxillary Arch_2500_K5
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_500_k-means-cluster#5	SOX6 AKAP9 BRCA2 SMC3 KIF21A KIF5C KIF20B	2.74e-05	232	80	7	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_500_K5
CoexpressionAtlas	FacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_2500_k-means-cluster#3	NEPRO SMG7 BRCA2 SMC3 KIF21A KIF14 TXLNG MAML3 KIF20B RNF111	3.06e-05	532	80	10	Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_2500_K3
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000	SOX6 USF3 AKAP9 SMG7 BRCA2 MYO5A SMC3 NKX2-1 KIF21A KIF5C MAML3 CEP97 KIF20B	7.78e-05	989	80	13	Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000
CoexpressionAtlas	FacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_500_k-means-cluster#4	AKAP9 BRCA2 KIF21A KIF5C MAML3 KIF20B	8.72e-05	192	80	6	Facebase_RNAseq_e10.5_Lateral Nasal Eminence_500_K4
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_500	SOX6 AKAP9 BRCA2 SMC3 NKX2-1 KIF21A KIF5C MAML3 KIF20B	1.06e-04	498	80	9	Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_500
CoexpressionAtlas	FacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_1000_k-means-cluster#5	NEPRO BRCA2 SMC3 KIF21A MAML3 KIF20B	1.22e-04	204	80	6	Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_1000_K5
CoexpressionAtlas	kidney_adult_Mesangium_Meis_k-means-cluster#4_top-relative-expression-ranked_100	GBP6 GBP7	1.39e-04	5	80	2	gudmap_kidney_adult_Mesangium_Meis_k4_100
CoexpressionAtlas	facebase_RNAseq_e10.5_NeuroEpith_central_2500_K4	SOX6 SOX5 AKAP9 BRCA2 MYO5A SMC3 CEP112 KIF21A KIF14 KIF5C HMMR CADPS2 CEP97 KIF20B SMAD4	1.61e-04	1370	80	15	facebase_RNAseq_e10.5_NeuroEpith_central_2500_K4
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000_k-means-cluster#2	USF3 AKAP9 BRCA2 MYO5A SMC3 KIF5C KIF20B	1.72e-04	311	80	7	Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000_K2
CoexpressionAtlas	facebase_RNAseq_e10.5_Emin_MedNas_2500	SOX6 SOX5 AKAP9 BRCA2 MYO5A SMC3 ERC1 KIF21A CGN KIF14 KIF5C HMMR POF1B CEP97 KIF20B	2.28e-04	1414	80	15	facebase_RNAseq_e10.5_Emin_MedNas_2500
CoexpressionAtlas	kidney_adult_RenMedVasc_Tie2_k-means-cluster#4_top-relative-expression-ranked_200	GBP6 ANGPT2 GBP7	2.59e-04	33	80	3	gudmap_kidney_adult_RenMedVasc_Tie2_k4_200
CoexpressionAtlas	FacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_2500_k-means-cluster#1	NEPRO MED30 RNF2 AKAP9 BRCA2 SMC3 MAML3 KIF20B	3.85e-04	469	80	8	Facebase_RNAseq_e8.5_Floor Plate_2500_K1
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_top-relative-expression-ranked_2500_k-means-cluster#4	SOX6 TRIM33 SLK RNF2 KIF21A KIF5C HMMR INPP5F MAML3	3.96e-04	595	80	9	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_2500_K4
ToppCell	Bronchial-NucSeq\|Bronchial / Cell types per location group and 10X technology with lineage, and cell group designations	SOX5 ARHGAP24 ERC1 EXOC6B RORA CADPS2 MAML3	8.39e-08	196	83	7	ab53c742866945545a92e2e61850d63c80d9a2a6
ToppCell	Tracheal-NucSeq\|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations	SOX5 KMT2C ERC1 EXOC6B RORA CADPS2 MAML3	9.31e-08	199	83	7	94b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SOX5 HDAC4 MYO5A ERC1 SCN3A CADPS2	5.96e-07	162	83	6	285e6d553f485fd9f1075c4e1b940da251b5ea35
ToppCell	TCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-5\|TCGA-Ovary / Sample_Type by Project: Shred V9	MIA3 USF3 SMG7 ERC1 GON4L MAML3	6.88e-07	166	83	6	32d2eaf8a5d03881bf74d680825af2d5110b082d
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SOX5 HDAC4 MYO5A ERC1 SCN3A CADPS2	1.38e-06	187	83	6	e3095455d2f255854f339f6b05fa87852af0700f
ToppCell	wk_20-22-Epithelial\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	NKX2-1 ODAD1 KIF21A CGN CCDC74A CFAP45	1.86e-06	197	83	6	468071c1911cdf8e8806a78dbceb95379e28ae91
ToppCell	Parenchymal-NucSeq\|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations	SOX5 ARHGAP24 ERC1 EXOC6B CADPS2 MAML3	1.92e-06	198	83	6	1996373bdccc55aac347d349bd22f6aad6d0c668
ToppCell	(10)_Ciliated-(2)_GFP_FOXI1\|(10)_Ciliated / shred by cell type by condition	AKAP9 SMC3 KIF21A CHMP5 ANKRD18A ANKRD36	1.97e-06	199	83	6	61b1ed2db71b96157b92b7535d1955a4033098da
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC-OPC-E\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SOX6 SOX5 SCN1A SCN3A CEP97	1.06e-05	155	83	5	77fdae85d36efb776db977eb424b32487ef222e4
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SOX5 HDAC4 MYO5A SCN3A CADPS2	1.40e-05	164	83	5	6fb2136168f430babfeb81ca7e151ca7a8092ec4
ToppCell	P28-Epithelial-airway_epithelial_cell-ciliated_cell_of_airway\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	SOX6 DNHD1 KMT2C NKX2-1 CGN	1.57e-05	168	83	5	8c8dbdbc7053f34e4ca0c5067af502fbea109fc1
ToppCell	saliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_B-B_cell-B_c01-TCL1A\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ODAD1 KIF21A CFAP45 CADPS2 ANKRD18B	1.57e-05	168	83	5	9a8709d34865cfa668d8f3335dc34fc86fc32482
ToppCell	LPS-IL1RA+antiTNF-Endothelial-Endothelial-FOXM1\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	BRCA2 CCDC150 KIF14 HMMR KIF20B	1.61e-05	169	83	5	e0607af8ae8609d43e26ff2a2cab92650bfcd5b7
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling-Cycling_Distal_Convoluted_Tubule_Cell_G2M\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	BRCA2 SCN3A KIF14 HMMR KIF20B	1.91e-05	175	83	5	876cea684faf42ff3eb4623ad6d7a1fb1276ee02
ToppCell	droplet-Limb_Muscle-MUSCLE-30m\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GBP6 AKAP9 GBP7 SMC3 PALMD	2.07e-05	178	83	5	01dafd19de04eff459253eaa9a35debf8f3deedf
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SOX6 SOX5 HDAC4 SCN3A CADPS2	2.13e-05	179	83	5	d3438fed0d85d5ed5afa8ff820c45143d77b6c0d
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	BRCA2 SCN3A KIF14 HMMR KIF20B	2.19e-05	180	83	5	401df9cddcbca1eb8f0d2687bcacd98e95dc1493
ToppCell	LPS-IL1RA-Endothelial-Endothelial-FOXM1\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	BRCA2 CCDC150 KIF14 HMMR KIF20B	2.19e-05	180	83	5	334e2b1f6eb7d4ece20b1c7b02107863f913237f
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SOX5 HDAC4 MYO5A ERC1 CADPS2	2.25e-05	181	83	5	b7c85fbef3c06d5dc32a2a58f8d3dfabf1d79d9f
ToppCell	10x5'-bone_marrow-Lymphocytic_T_CD4/8-lo-Cycling_T\|bone_marrow / Manually curated celltypes from each tissue	BRCA2 SMC3 KIF14 HMMR KIF20B	2.37e-05	183	83	5	a48a6313f2f144586951cece97ec31f6d72361df
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SOX5 HDAC4 ERC1 SCN3A CADPS2	2.37e-05	183	83	5	d340ab5a77e8d819a1dfb4ca3e9a4b9bc988923c
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Neuronal-Glial_immature-cycling_ENCC/glia\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	BRCA2 KIF14 KIF5C HMMR KIF20B	2.37e-05	183	83	5	29b62dd542bc3f8df843998f577724f3818d4271
ToppCell	Brain_organoid-organoid_Kanton_Nature\|Brain_organoid / Sample Type, Dataset, Time_group, and Cell type.	AKAP9 SMC3 NKX2-1 KIF21A TXLNG	2.49e-05	185	83	5	857c7ca8493e91ef1d0078ddafd6082020f9b169
ToppCell	Control-T_cells-Cycling_NK/T_cells\|Control / group, cell type (main and fine annotations)	BRCA2 CCDC150 KIF14 HMMR KIF20B	2.49e-05	185	83	5	9766216b41ee62bbac4caa25cb98ec5627a24075
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	BRCA2 CCDC150 KIF14 HMMR KIF20B	2.49e-05	185	83	5	30e041d6f6e310d64809e9d6d93cd30052972f3b
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SOX5 HDAC4 ERC1 SCN3A CADPS2	2.62e-05	187	83	5	f6217d0dd425eac76900b44a4e48f45475f3ac36
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	BRCA2 CCDC150 KIF14 HMMR KIF20B	2.62e-05	187	83	5	9351fa87b69a951af85b10bf91fe9b1cce8c0517
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SOX5 HDAC4 MYO5A ERC1 CADPS2	2.69e-05	188	83	5	e30a4ddac0da8cdcf621d98e28e3895cd9307e7a
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SOX5 HDAC4 ERC1 SCN3A CADPS2	2.76e-05	189	83	5	3a295c215b5c18e7c673f92b7af5be523421682c
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2-D231\|Adult / Lineage, Cell type, age group and donor	SOX6 SOX5 NKX2-1 SCN1A CADPS2	2.76e-05	189	83	5	dab54a52358f66a8a9460cd6089a06c5fa7e7a5d
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SOX5 HDAC4 MYO5A ERC1 CADPS2	2.76e-05	189	83	5	c9565e962a13a7713056ec3dbb1b67d24f9889c7
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SOX5 HDAC4 MYO5A ERC1 CADPS2	2.76e-05	189	83	5	fc88c51ace7d883c01617f3f9b5fab70cc91cc09
ToppCell	Control-Endothelial-Endothelial-FOXM1\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	BRCA2 CCDC150 KIF14 HMMR KIF20B	2.76e-05	189	83	5	1e1499b062d9c647c8f38b0c4e0d871d159be5dd
ToppCell	3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal-Deuterosomal_L.0.3.4.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ZNF487 BRCA2 CCDC74A CFAP45 ANKRD36	2.83e-05	190	83	5	0adb24dafa077156bbc73a8d8cbf3d9eeb6e08df
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SOX5 HDAC4 MYO5A ERC1 CADPS2	2.83e-05	190	83	5	11d3c31167ea71809b4cc3757a0c6ea54a448602
ToppCell	3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ZNF487 BRCA2 CCDC74A CFAP45 ANKRD36	2.83e-05	190	83	5	05455775845f4ded5c27e7b83242078d23162aaf
ToppCell	pdx-Tumor_cells-T1\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	BRCA2 CEP112 KIF14 HMMR KIF20B	2.83e-05	190	83	5	d06ee5f89f1cec8db6897fe3b2a890a07cd3697b
ToppCell	3'_v3-bone_marrow-Lymphocytic_T_CD4/8-lo-Cycling_T\|bone_marrow / Manually curated celltypes from each tissue	BRCA2 SMC3 KIF14 HMMR KIF20B	2.90e-05	191	83	5	210a0f1a71df2508cbfc73d6868a2122338b9a1c
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SOX5 HDAC4 MYO5A SCN3A CADPS2	2.90e-05	191	83	5	96b78b4e819ea6052334bfcbc7abbf35897df885
ToppCell	nucseq\|World / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	KMT2C ERC1 MCF2L2 MAML3 RNF111	3.05e-05	193	83	5	779276e775cb2492e8dd36436295a536084a6415
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6\|TCGA-Prostate / Sample_Type by Project: Shred V9	TRIM33 USF3 AKAP9 KIF21A CEP97	3.05e-05	193	83	5	abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_A\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MYO5A KIF21A SCN3A MCF2L2 KIF5C	3.05e-05	193	83	5	a189d46c39067b717509cd144e0225cc93d7731d
ToppCell	severe-low-quality_cells\|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	TRIM33 AKAP9 MCF2L2 RORA ANKRD36	3.05e-05	193	83	5	9337bc93e3904c7fc7c93c328518bcd6453b1e8c
ToppCell	human_hepatoblastoma-Tumor_cells-T1\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	BRCA2 CEP112 KIF14 HMMR KIF20B	3.05e-05	193	83	5	4b9fa2a4424f8abe63fa7bee78db93dda04ab15f
ToppCell	facs-Trachea-3m-Epithelial-glandular_epithelial-lung_secretory_cell-mucous\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NKX2-1 CGN CCDC74A DUOX2 LMOD2	3.05e-05	193	83	5	c5925b3b5d19098e3987789d68a493d7fd548ac9
ToppCell	facs-Trachea-3m-Epithelial-glandular_epithelial\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NKX2-1 CGN CCDC74A DUOX2 LMOD2	3.05e-05	193	83	5	6905de261d90dfe3dd2c2cf5b2e26afb2bcc3d5b
ToppCell	facs-Trachea-3m-Epithelial-glandular_epithelial-lung_secretory_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NKX2-1 CGN CCDC74A DUOX2 LMOD2	3.05e-05	193	83	5	f73630725f093c646bdaf178c39505c04a16e2c6
ToppCell	3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_T/NK-T_cell-T_cells_proliferating-T_cells_proliferating_L.1.1.3.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	KIF14 RORA KIF5C HMMR KIF20B	3.05e-05	193	83	5	b835d28de9daeec5213172c96f62b332cda53bb5
ToppCell	wk_20-22-Epithelial-Proximal_epithelial-MUC16+_ciliated\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	GBP6 ODAD1 KIF21A CGN CFAP45	3.13e-05	194	83	5	756082a0f5953b52229bb60d40b84701cb6cb23d
ToppCell	5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_proliferating-Alveolar_macrophage_proliferating_L.1.0.7.3\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	BRCA2 CCDC150 KIF14 HMMR KIF20B	3.13e-05	194	83	5	e5b81a8e52259a54a911c1c2ac932c98c988318d
ToppCell	3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_T/NK-T_cell-T_cells_proliferating\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	KIF14 RORA KIF5C HMMR KIF20B	3.21e-05	195	83	5	67670d16ddd5d5ab7bc2254df329f5a7b2581556
ToppCell	3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_T/NK-T_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	KIF14 RORA KIF5C HMMR KIF20B	3.21e-05	195	83	5	23dc2f8a3a038195a31feee7e3a51094a7a7c23e
ToppCell	COVID-19-T_cells-Cycling_NK/T_cells\|COVID-19 / group, cell type (main and fine annotations)	BRCA2 CCDC150 KIF14 HMMR KIF20B	3.21e-05	195	83	5	764ed100c28d9bc93ee5ecabc5291c8f184d78da
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_cycling\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	BRCA2 CCDC150 KIF14 HMMR KIF20B	3.21e-05	195	83	5	926eb3fc5d028be936885bea0654a77db3107234
ToppCell	NS-critical-LOC-Epithelial-Ciliated\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	ODAD1 KIF21A CCDC74A CFAP45 PALMD	3.21e-05	195	83	5	34e37cff4849696ca4ba5dd8fd2cf98fed8bc912
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Mesenchymal\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGAP24 AKAP9 CEP112 RORA NEB	3.21e-05	195	83	5	5c86fddd6d0530beecf45ea5ba6b823123847696
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_cycling\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	BRCA2 CCDC150 KIF14 HMMR KIF20B	3.29e-05	196	83	5	1d2e0b328eb822db7521b5f5724d4bd17c0bad5f
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_cycling\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	BRCA2 CCDC150 KIF14 HMMR KIF20B	3.29e-05	196	83	5	73f951f7712e0aa3323676b9a4b7944d21d347c4
ToppCell	severe-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	KMT2C AKAP9 MCF2L2 RORA ANKRD36	3.37e-05	197	83	5	57ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCell	Parenchymal-10x3prime_v2-Epithelial-Epi_airway_ciliated-Deuterosomal\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	GBP6 CCDC74A CFAP45 KIF14 CFAP99	3.37e-05	197	83	5	861e8df9bd74dc5e17bafdc1fb3fef546753c73a
ToppCell	LPS_anti-TNF-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	AKAP9 SCN1A KIF21A CADPS2 TP53BP2	3.37e-05	197	83	5	1485933986921ff45669d9b7501c8d17050b3e97
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_cycling\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	BRCA2 CCDC150 KIF14 HMMR KIF20B	3.37e-05	197	83	5	8b616cde333bdbc0c591035ad9e4949155866245
ToppCell	Tracheal-NucSeq-Epithelial-Epi_airway_ciliated-Deuterosomal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ODAD1 CCDC74A CFAP45 KIF14 CFAP99	3.45e-05	198	83	5	f31790442ef142f1c0c49bf3daf2d0efb193d2c9
ToppCell	(11)_FOXN4+-(2)_GFP_FOXI1\|(11)_FOXN4+ / shred by cell type by condition	TRIM33 AKAP9 SMC3 CHMP5 KIF20B	3.45e-05	198	83	5	76d40b8c2f8399725b3a62ee2ae0896559cf91eb
ToppCell	Tracheal-NucSeq-Epithelial-Epi_airway_basal-Dividing_Basal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	BRCA2 CCDC150 KIF14 HMMR KIF20B	3.45e-05	198	83	5	f088badb90c6c2d916195f5649eda102119c9ac6
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Newborn-35\|World / Primary Cells by Cluster	TRIM33 AKAP9 CELF1 ANKRD36 PALMD	3.45e-05	198	83	5	de5214a85fe017eb23d4aa8af624464f062ec57e
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-FOXM1\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	BRCA2 CCDC150 KIF14 HMMR KIF20B	3.53e-05	199	83	5	98575fcce726589e93fbb4df1aab03e57cb56076
ToppCell	LPS_IL1RA-Endothelial-Endothelial-FOXM1\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	BRCA2 CCDC150 KIF14 HMMR KIF20B	3.53e-05	199	83	5	be2276c9a1994579ba1d2998b49bf549c1324d44
ToppCell	LPS_IL1RA_TNF-Endothelial-Endothelial-FOXM1\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	BRCA2 CCDC150 KIF14 HMMR KIF20B	3.62e-05	200	83	5	4cfe08878a6981bf7b3567f9e82192d8f060ddde
ToppCell	Control_saline-Endothelial-Endothelial-FOXM1\|Control_saline / Treatment groups by lineage, cell group, cell type	BRCA2 CCDC150 KIF14 HMMR KIF20B	3.62e-05	200	83	5	9bbc7b5561151f6ff65f40b3226271def732e5d9
ToppCell	LPS_IL1RA_TNF-Epithelial_airway-airway_epithelial\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	CFAP45 DUOX2 KIF5C POF1B CFAP99	3.62e-05	200	83	5	da12821e8a0657869ca0f75d351cce2d7605a505
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW26-Stem_cells-Neuroepithelial_cell\|GW26 / Sample Type, Dataset, Time_group, and Cell type.	BRCA2 CCDC150 KIF14 HMMR KIF20B	3.62e-05	200	83	5	203b9a5de4430713da01b3331e69381db449a3a0
ToppCell	Tracheal-NucSeq-Epithelial-Epi_airway_ciliated\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ODAD1 CCDC74A CFAP45 ANKRD18B CFAP99	3.62e-05	200	83	5	73ac1cf40ddd764be1100cbfaaa29563665457d8
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW26-Stem_cells\|GW26 / Sample Type, Dataset, Time_group, and Cell type.	BRCA2 CCDC150 KIF14 HMMR KIF20B	3.62e-05	200	83	5	a854e19703dc920e48304541e2b06ed013292f3e
ToppCell	Severe-T/NK_proliferative\|Severe / Disease group and Cell class	BRCA2 SMC3 KIF14 HMMR KIF20B	3.62e-05	200	83	5	4723613a9f56bff422fc98722128d57b6adf3c5d
ToppCell	Sepsis-URO-Lymphocyte-T/NK-T/NK_proliferative\|URO / Disease, condition lineage and cell class	BRCA2 KIF14 DIXDC1 HMMR KIF20B	3.62e-05	200	83	5	f277db6cc288a52a5426120c1067608700ee8ccc
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_alveolar-Dividing_AT2\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	BRCA2 CCDC150 KIF14 HMMR KIF20B	3.62e-05	200	83	5	af3dc76b4507bf4edd265169f5dfbbb8a19eb394
ToppCell	356C-Myeloid-Dendritic-cDC_proliferating_1\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	BRCA2 SMC3 KIF14 HMMR KIF20B	3.62e-05	200	83	5	5b014c658eecc5e73679e5feb7a2aaa3d297001d
ToppCell	LPS_IL1RA_TNF-Epithelial_airway\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	CFAP45 DUOX2 KIF5C POF1B CFAP99	3.62e-05	200	83	5	72c1d9eeaed4b3ee6b6c602e8aa29efc2e8744eb
ToppCell	COVID-19_Mild-Neu_1\|World / 5 Neutrophil clusters in COVID-19 patients	SOX5 USF3 CFAP45 SHOX	8.80e-05	125	83	4	e58c208b4355252ceabe04a468dd19a1f436182c
ToppCell	Hippocampus-Macroglia-POLYDENDROCYTE-P5-P5_1-Sox4-POLYDENDROCYTE_(Neurogenesis.Sox4.Cdc20)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	CCDC150 KIF14 HMMR KIF20B	1.06e-04	131	83	4	f9fb8d74ca720b81fd5910cc975510359a8ef751
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma-7\|TCGA-Brain / Sample_Type by Project: Shred V9	BRCA2 KIF14 ANKRD20A8P KIF20B	1.22e-04	136	83	4	d94f0fbeb7b80d4cf0687d1924ebf8f9dd07358c
ToppCell	healthy_donor-Lymphocytic-T_cell-CD4+_T_cell_(ISG_high)\|healthy_donor / Disease condition, Lineage, Cell class and subclass	SOX6 GBP7 SHOX DIXDC1	1.29e-04	138	83	4	97f5dc17522462133e582b508ad0ef036e656872
ToppCell	PND01-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_G2M\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYO5A KIF14 HMMR KIF20B	1.44e-04	142	83	4	be63c48794a227ea55978524c0f5935342fc455e
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_B\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	SOX5 BRCA2 ANKRD20A8P ANKRD18B	1.73e-04	149	83	4	14d2e8cab97108d8fa94e540c1957b73ed32dc73
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_B-B_cell\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	SOX5 BRCA2 ANKRD20A8P ANKRD18B	1.73e-04	149	83	4	54c9c6282f5f5de43dfaf2972fab3e3dcf9838a3
ToppCell	COVID-19_Mild\|World / 5 Neutrophil clusters in COVID-19 patients	SOX5 USF3 CFAP45 SHOX	1.87e-04	152	83	4	2ff0980dfd8d430cca14649151d856edef115720
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SOX5 ODAD1 DUOX2 KIF5C	1.87e-04	152	83	4	bd1f36b436d8ab7dd8420f595b97d851eab31a38
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SOX5 ODAD1 DUOX2 KIF5C	1.87e-04	152	83	4	ee329249a034a969a16b26a224aa04249d67382d
ToppCell	3'_v3-Lung-Lymphocytic_Invariant-Inducer-like-MAIT\|Lung / Manually curated celltypes from each tissue	GBP6 RORA KIF5C ANKRD18B	2.02e-04	155	83	4	72c61be0a8d3ee10600a33c58fb01c35fd3f14d4
ToppCell	10x5'-Lung-Lymphocytic_T_CD4-T_CD4/CD8\|Lung / Manually curated celltypes from each tissue	CEP112 ODAD1 KIF21A ANKRD36	2.07e-04	156	83	4	10d191e29b16cae8238e8df6c0ff38882253f34e
ToppCell	10x5'-Liver-Lymphocytic_T_CD4-Tfh\|Liver / Manually curated celltypes from each tissue	ERC1 ANKRD18A KIF5C CEP97	2.07e-04	156	83	4	85bc34ff507f9a66c6e3ba7a3ffd5416d0073ccf
ToppCell	COVID-19_Moderate-multiplets\|World / disease group, cell group and cell class	CCDC74A RORA ANKRD18A ANKRD36	2.07e-04	156	83	4	afdc025fa75e7926b1cc182c4a33654a2186abb1
ToppCell	droplet-Lung-nan-3m-Lymphocytic-Proliferating_NK\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF14 DIXDC1 HMMR KIF20B	2.17e-04	158	83	4	ee8ce3cd202807df692b28bb1a81827d49d73862
ToppCell	PND07-Endothelial-Endothelial_lymphatic\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ANGPT2 SCN1A SCN3A DUOX2	2.33e-04	161	83	4	133b4fadb499e842c19f573f9cf09ce08c1d4813
ToppCell	PND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ANGPT2 SCN1A SCN3A DUOX2	2.33e-04	161	83	4	9466b8658244116f8d21f2f88fb8c2d184b1bdf2
ToppCell	saliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c03-GZMK\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	KIF21A SCN3A CPSF3 KIF20B	2.33e-04	161	83	4	d72c572613f8eff3251cb7b1e9dcc76d193b2f21
ToppCell	Healthy/Control-Treg\|World / Disease group and Cell class	CGN MCF2L2 RORA KIF20B	2.33e-04	161	83	4	457297cda5c9cee3bcc069fdecbbe24def027e5f
ToppCell	PND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ANGPT2 SCN1A SCN3A DUOX2	2.33e-04	161	83	4	cb177ca10d848d0e25399ab5ebfcde1071fb94c2
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c06-NR4A2\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	RORA ANKRD18A ANKRD36 KIF5C	2.39e-04	162	83	4	80317c4253bf8e897782e562f29835f181c65b98
Computational	Genes in the cancer module 205.	SOX6 ANGPT2 HDAC5 EXOC6B KIF14 DUOX2 DIXDC1 DZIP1 INPP5F	2.07e-06	305	42	9	MODULE_205
Computational	Neighborhood of PPM1D	CELF1 SMC3 SYNC	1.35e-04	26	42	3	GCM_PPM1D
Drug	Hexetidine [141-94-6]; Down 200; 11.8uM; PC3; HT_HG-U133A	ARHGAP24 HDAC5 SMG7 CELF1 GON4L PKN1 PALMD SMAD4	6.66e-07	199	83	8	6319_DN
Drug	Thioguanosine [85-31-4]; Down 200; 12.6uM; MCF7; HT_HG-U133A	TRIM33 SLK BRCA2 ITSN1 KIF14 HMMR TP53BP2	5.53e-06	187	83	7	4989_DN
Drug	Thioguanosine [85-31-4]; Down 200; 12.6uM; MCF7; HT_HG-U133A	TRIM33 BRCA2 SMC3 ITSN1 SREBF2 KIF14 HMMR	6.13e-06	190	83	7	2619_DN
Drug	Skimmianine [83-95-4]; Down 200; 15.4uM; PC3; HT_HG-U133A	PTPN2 ARHGAP24 RNF2 BRCA2 EXOC6B GON4L KIF5C	7.77e-06	197	83	7	5766_DN
Drug	11-deoxy-16,16-dimethyl Prostaglandin E2; Down 200; 10uM; PC3; HT_HG-U133A	RAD52 SMG7 CEP112 SREBF2 PALMD CADPS2 HIRA	8.03e-06	198	83	7	7519_DN
Disease	Idiopathic pulmonary arterial hypertension	HDAC5 HDAC4 SMAD4	1.05e-05	16	80	3	C3203102
Disease	Familial primary pulmonary hypertension	HDAC5 HDAC4 SMAD4	1.27e-05	17	80	3	C0340543
Disease	Brachydactyly	HDAC4 SMAD4	4.34e-05	4	80	2	C0221357
Disease	PULMONARY HYPERTENSION, PRIMARY, DEXFENFLURAMINE-ASSOCIATED	HDAC5 HDAC4	1.51e-04	7	80	2	C1969342
Disease	Pulmonary Hypertension, Primary, Fenfluramine-Associated	HDAC5 HDAC4	1.51e-04	7	80	2	C1969343
Disease	Pulmonary Hypertension, Primary, 1, With Hereditary Hemorrhagic Telangiectasia	HDAC5 HDAC4	1.51e-04	7	80	2	C3714844
Disease	Pulmonary Hypertension, Primary, 1	HDAC5 HDAC4	1.51e-04	7	80	2	C4552070
Disease	Parkinson disease	DNAH17 RORA INPP5F BIN3 IP6K2 SMAD4	2.42e-04	321	80	6	MONDO_0005180
Disease	Pancreatic carcinoma, familial	BRCA2 SMAD4	2.58e-04	9	80	2	C2931038
Disease	Liver Diseases, Parasitic	KMT2C SMAD4	2.58e-04	9	80	2	C0023897
Disease	generalized epilepsy with febrile seizures plus 2 (implicated_via_orthology)	SCN1A SCN3A	3.22e-04	10	80	2	DOID:0111294 (implicated_via_orthology)
Disease	Dravet syndrome (implicated_via_orthology)	SCN1A SCN3A	3.22e-04	10	80	2	DOID:0080422 (implicated_via_orthology)
Disease	generalized epilepsy with febrile seizures plus (implicated_via_orthology)	SCN1A SCN3A	4.71e-04	12	80	2	DOID:0060170 (implicated_via_orthology)
Disease	Congenital Hypothyroidism	NKX2-1 DUOX2	5.55e-04	13	80	2	C0010308
Disease	Benign tumor of pancreas	BRCA2 SMAD4	5.55e-04	13	80	2	C0347284
Disease	diffuse idiopathic skeletal hyperostosis	MED30 RORA	7.45e-04	15	80	2	EFO_0007236
Disease	skin pigmentation	RORA CADPS2 RNF111	8.84e-04	69	80	3	EFO_0003784
Disease	facial asymmetry measurement	SOX5 RORA	1.20e-03	19	80	2	EFO_0009751
Disease	Pancreatic carcinoma	BRCA2 SMAD4	1.20e-03	19	80	2	C0235974
Disease	pulmonary hypertension (biomarker_via_orthology)	ANGPT2 HDAC5 SMAD4	1.36e-03	80	80	3	DOID:6432 (biomarker_via_orthology)
Disease	Intellectual Disability	KMT2C HDAC4 SCN1A SCN3A GON4L RORA	1.37e-03	447	80	6	C3714756
Disease	BREAST CANCER	BRCA2 HMMR	1.47e-03	21	80	2	114480
Disease	skin aging measurement	RAD52 HDAC4 CELF1 CEP112	1.51e-03	181	80	4	EFO_0008006
Disease	C-reactive protein measurement	SOX6 SOX5 PTPN2 CELF1 DNAH17 CFAP45 EXOC6B RORA MAML3 IP6K2	1.54e-03	1206	80	10	EFO_0004458
Disease	anxiety disorder (implicated_via_orthology)	SCN1A SCN3A	1.62e-03	22	80	2	DOID:2030 (implicated_via_orthology)
Disease	nephrosis (biomarker_via_orthology)	ANGPT2 SREBF2	1.62e-03	22	80	2	DOID:2527 (biomarker_via_orthology)
Disease	alanine measurement	MED30 ANGPT2 RORA	1.67e-03	86	80	3	EFO_0009765
Disease	Papillary thyroid carcinoma	TRIM33 NKX2-1 ERC1	1.67e-03	86	80	3	C0238463
Disease	Intrahepatic Cholangiocarcinoma	KMT2C SMAD4	1.93e-03	24	80	2	C0345905
Disease	Extrahepatic Cholangiocarcinoma	KMT2C SMAD4	1.93e-03	24	80	2	C3805278
Disease	nevus count, cutaneous melanoma	SOX6 MIA3 HDAC4	1.96e-03	91	80	3	EFO_0000389, EFO_0004632
Disease	Neurodevelopmental Disorders	KMT2C SMC3 SCN1A	2.09e-03	93	80	3	C1535926
Disease	multisite chronic pain	SOX6 SOX5 MAML3	2.22e-03	95	80	3	EFO_0010100
Disease	Cholangiocarcinoma	KMT2C SMAD4	2.26e-03	26	80	2	C0206698
Disease	Malignant tumor of breast	BRCA2 HMMR	2.44e-03	27	80	2	cv:C0006142
Disease	Breast neoplasm	BRCA2 HMMR	2.44e-03	27	80	2	cv:C1458155
Disease	Familial cancer of breast	BRCA2 HMMR	2.44e-03	27	80	2	cv:C0346153
Disease	neuroblastoma, cutaneous melanoma	SLK ARHGAP24	2.62e-03	28	80	2	EFO_0000389, EFO_0000621

Protein segments in the cluster

Peptide	Gene	Start	Entry
LRQQNQALEKQLEKM	AKAP9	2051	Q99996
KNKMLKNHLRNDNQE	ANKRD18A	256	Q8IVF6
QNDLRKTQQQTQEMK	ANKRD20A8P	696	Q5CZ79
VNAMNDKIRKQININ	CPSF3	286	Q9UKF6
DKEQKRMAQQLQQQM	CELF1	191	Q92879
GNQQEMKNNVEKVLQ	DIXDC1	76	Q155Q3
KKEMVEIQQNAVQNQ	ANGPT2	106	O15123
KNKMLKNHLRNDNQE	ANKRD18B	256	A2A2Z9
QRKQQLRDQENKFQM	CEP112	526	Q8N8E3
QNMLLQQQLDDARNK	ANKRD36	1726	A6QL64
QNIKKEMVLQRFHQQ	DNHD1	2991	Q96M86
NNFAERQKRLQAMQK	CCDC74A	356	Q96AQ1
QMNNLFQQKQRELVL	TP53BP2	216	Q13625
MKRQAKDKAAQQQLQ	NKX2-1	216	P43699
DRLVQQLKQQTQNRM	ERC1	966	Q8IUD2
RNQQVKQAFINMARK	OR6C1	291	Q96RD1
QKQLQQQFRERMEKQ	RAD52	261	P43351
TAQKVQQMKQRLNEN	PTPN2	361	P17706
QSLMQENKQRVEQQK	CFAP99	371	D6REC4
QKRMYEQQRDNLAQQ	CHMP5	71	Q9NZZ3
QEEMKKQNQQDQHQI	PALMD	61	Q9NP74
SQRKKMQEINNQKAN	KIF14	991	Q15058
FQLQRANKMELRKQQ	KIAA0100	1886	Q14667
KLNNLRKLHVNRNNM	LRRD1	416	A4D1F6
QSMVQKQLEQIRKQQ	KMT2C	3241	Q8NEZ4
EKHKQQFQQQQLQMN	HDAC4	491	P56524
EQLKQMAAQQQQRAK	MAML3	466	Q96JK9
QQLQRMKENAKHRNQ	IP6K2	186	Q9UHH9
KRMRLQQALAEQQQQ	MED31	111	Q9Y3C7
NMDKQRQKRLQEQKQ	LMOD2	351	Q6P5Q4
QEKMQRGFLAQKLQQ	DUOX2	1016	Q9NRD8
MQAEIKRINDENQKQ	CFAP45	311	Q9UL16
KLLMEQQNNIKDQGN	MCF2L2	951	Q86YR7
MKQRTIQQLKEQLNN	KIF20B	1336	Q96Q89
KQKLQEQQQQMEAQD	GBP6	506	Q6ZN66
EQELLRQKQKEQQQM	GBP7	501	Q8N8V2
MKQAQQQRNLDNIVL	EXOC6B	221	Q9Y2D4
QAVLHMEQRKQQQQQ	NUCB1	391	Q02818
MEQRKQQQQQQQGHK	NUCB1	396	Q02818
QQQKVLQQRMDKVHS	ODAD1	341	Q96M63
KRNLEQENQNLRMQV	POF1B	426	Q8WVV4
QKNQQLKQIMDQLRN	MED30	151	Q96HR3
NENLNAEMQNLKQKF	HMMR	311	O75330
NNEIQKKATMGQLQN	ARHGAP24	346	Q8N264
KANNAQNIERMKQIE	CCDC150	906	Q8NCX0
IANQKQIFAKMQEAN	CCDC63	131	Q8NA47
NHRQMLNDKKQAQIQ	BRCA2	2931	P51587
HNLQNRMQKAKQNIE	DNAH17	776	Q9UFH2
KQRFHQRQLMNQSQN	CEP97	296	Q8IW35
REIHNKQQLQKQKSM	ITSN1	611	Q15811
AQRKRLQQQMQQHVQ	GON4L	686	Q3T8J9
RMDAFNQEKVNQIQK	BIN3	91	Q9NQY0
DMARRQQKLNKQQLQ	CADPS2	106	Q86UW7
AKQQQEMLAAKRQQE	HDAC5	126	Q9UQL6
LVMQQQHQQFLEKQK	HDAC5	511	Q9UQL6
MLKYQRRQQQQQLDQ	HIRA	401	P54198
NQVQQNELKKMFIQC	INPP5F	1111	Q9Y2H2
QAMNRLQRGKKQQIE	RNF2	151	Q99496
NGVQLQQQKNKEMEQ	SYNC	426	Q9H7C4
NVTKERQMKLLQQQN	TRIM33	386	Q9UPN9
QQVYAQKHQQLQQMR	TRIM33	521	Q9UPN9
NQMQQIETQQRKFKA	SMC3	716	Q9UQE7
QEEKRQKNERMAQHQ	SLK	1111	Q9H2G2
QEEKILNMFRQQQKI	SYCP3	146	Q8IZU3
KAAGNQMNDRKIQQE	MIA3	561	Q5JRA6
NQQSQLAEKLKQQML	KIF5C	436	O60282
PQLAENKQQFRNMKQ	NBPF7P	46	P0C2Y1
KQMKINVQNNVDLGQ	NEPRO	281	Q6NW34
EQLLMQQKQKQQRGQ	SMG7	1116	Q92540
KVFDLRQCHRQMQQQ	SMAD4	436	Q13485
QNRRAKCRKQENQMH	SHOX	166	O15266
QQMLEQLKKQQEEAQ	SCN3A	446	Q9NY46
KQQGKAFQRARQMNI	PKN1	496	Q16512
NEQKLNNNKMHLRKA	DZIP1	516	Q86YF9
QMIEQLKKQQEAAQQ	SCN1A	446	P35498
EKQRQQMDLARQQQE	SOX6	221	P35712
EAQQSNKELQNMKRL	CGN	416	Q9P2M7
SQKQEKEMNGNQQEQ	RNF111	71	Q6ZNA4
LYAEVQKHRMQQQQR	RORA	156	P35398
NRARNIKNKVMVNQD	KIF21A	366	Q7Z4S6
QAMNKELQRLQAAQK	KIF21A	726	Q7Z4S6
NFNQKMVQLKEDQQR	SOGA1	616	O94964
QQVNHKLRQENMVLK	SREBF2	381	Q12772
QQRTLQQEVQMQKKR	USF3	1511	Q68DE3
QQEVQMQKKRNLVQG	USF3	1516	Q68DE3
IEKQRQQMELAKQQQ	SOX5	231	P35711
QRHNKTLKEENMQQA	TXLNG	216	Q9NUQ3
EQMKQQEVQLKQQLS	TXLNG	341	Q9NUQ3
LMEKRQENQDQHLQK	ZNF487	116	B1APH4
ENKIMQLQRKVDEQN	MYO5A	926	Q9Y4I1
EQVLAKNNALNMNKR	NEB	3436	P20929