Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	DNA-binding transcription factor activity, RNA polymerase II-specific	SOX15 TGIF1 DUX4L2 FEV CDX1 DUX4 CDX2 LHX3 HOXC12 ERG DUX4L4 EGR4 NEUROG3 NPAS4 ZNF516 DUX4L9	4.44e-09	1412	40	16	GO:0000981
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	SOX15 TGIF1 DUX4L2 FEV CDX1 DUX4 CDX2 LHX3 ERG DUX4L4 EGR4 FUBP1 NEUROG3 NPAS4 ZNF516 DUX4L9	7.11e-09	1459	40	16	GO:0000977
GeneOntologyMolecularFunction	RNA polymerase II cis-regulatory region sequence-specific DNA binding	SOX15 TGIF1 FEV CDX1 DUX4 CDX2 LHX3 ERG EGR4 FUBP1 NEUROG3 NPAS4 ZNF516	4.94e-07	1244	40	13	GO:0000978
GeneOntologyMolecularFunction	cis-regulatory region sequence-specific DNA binding	SOX15 TGIF1 FEV CDX1 DUX4 CDX2 LHX3 ERG EGR4 FUBP1 NEUROG3 NPAS4 ZNF516	6.31e-07	1271	40	13	GO:0000987
GeneOntologyMolecularFunction	DNA-binding transcription activator activity, RNA polymerase II-specific	SOX15 FEV CDX1 DUX4 LHX3 ERG EGR4 NEUROG3 NPAS4	1.27e-06	560	40	9	GO:0001228
GeneOntologyMolecularFunction	DNA-binding transcription activator activity	SOX15 FEV CDX1 DUX4 LHX3 ERG EGR4 NEUROG3 NPAS4	1.38e-06	566	40	9	GO:0001216
GeneOntologyMolecularFunction	ryanodine-sensitive calcium-release channel activity	RYR2 RYR3	2.34e-05	4	40	2	GO:0005219
GeneOntologyMolecularFunction	calcium-induced calcium release activity	RYR2 RYR3	5.84e-05	6	40	2	GO:0048763
GeneOntologyMolecularFunction	intracellularly gated calcium channel activity	RYR2 RYR3	5.87e-04	18	40	2	GO:0015278
GeneOntologyMolecularFunction	methyl-CpG binding	CDX1 CDX2	1.75e-03	31	40	2	GO:0008327
GeneOntologyMolecularFunction	ligand-gated calcium channel activity	RYR2 RYR3	1.75e-03	31	40	2	GO:0099604
GeneOntologyMolecularFunction	intracellularly ligand-gated monoatomic ion channel activity	RYR2 RYR3	1.99e-03	33	40	2	GO:0005217
GeneOntologyMolecularFunction	calcium channel activity	PKD2L1 RYR2 RYR3	2.19e-03	129	40	3	GO:0005262
GeneOntologyMolecularFunction	ligand-gated monoatomic cation channel activity	PKD2L1 RYR2 RYR3	2.76e-03	140	40	3	GO:0099094
GeneOntologyMolecularFunction	chromatin binding	NELFE SOX15 TGIF1 ERG NEUROG3 POLR2A	3.30e-03	739	40	6	GO:0003682
GeneOntologyMolecularFunction	calcium ion transmembrane transporter activity	PKD2L1 RYR2 RYR3	3.41e-03	151	40	3	GO:0015085
GeneOntologyMolecularFunction	ligand-gated monoatomic ion channel activity	PKD2L1 RYR2 RYR3	6.75e-03	193	40	3	GO:0015276
GeneOntologyMolecularFunction	ligand-gated channel activity	PKD2L1 RYR2 RYR3	7.15e-03	197	40	3	GO:0022834
GeneOntologyBiologicalProcess	positive regulation of transcription by RNA polymerase II	NELFE SOX15 FEV CDX1 DUX4 CDX2 LHX3 ERG EGR4 VGLL2 NEUROG3 NPAS4	7.95e-06	1390	40	12	GO:0045944
GeneOntologyBiologicalProcess	regulation of somitogenesis	CDX1 CDX2	7.65e-05	7	40	2	GO:0014807
GeneOntologyCellularComponent	chromatin	NELFE SOX15 TGIF1 FEV CDX1 CDX2 LHX3 ERG EGR4 NEUROG3 NPAS4 POLR2A	1.74e-05	1480	41	12	GO:0000785
GeneOntologyCellularComponent	calcium channel complex	PKD2L1 RYR2 RYR3	3.96e-04	73	41	3	GO:0034704
GeneOntologyCellularComponent	cytoplasmic side of plasma membrane	ANK1 RYR2 RYR3 MTSS2	4.66e-04	185	41	4	GO:0009898
GeneOntologyCellularComponent	sarcoplasmic reticulum	ANK1 RYR2 RYR3	6.85e-04	88	41	3	GO:0016529
GeneOntologyCellularComponent	cytoplasmic side of membrane	ANK1 RYR2 RYR3 MTSS2	1.05e-03	230	41	4	GO:0098562
GeneOntologyCellularComponent	sarcoplasm	ANK1 RYR2 RYR3	1.45e-03	114	41	3	GO:0016528
Domain	Homeobox	TGIF1 CDX1 DUX4 CDX2 LHX3 HOXC12	6.09e-06	234	37	6	PF00046
Domain	HOX	TGIF1 CDX1 DUX4 CDX2 LHX3 HOXC12	6.55e-06	237	37	6	SM00389
Domain	Homeobox_dom	TGIF1 CDX1 DUX4 CDX2 LHX3 HOXC12	6.88e-06	239	37	6	IPR001356
Domain	HOMEOBOX_2	TGIF1 CDX1 DUX4 CDX2 LHX3 HOXC12	6.88e-06	239	37	6	PS50071
Domain	HTH_motif	CDX1 DUX4 CDX2 HOXC12	1.03e-05	69	37	4	IPR000047
Domain	RyR	RYR2 RYR3	1.14e-05	3	37	2	PF02026
Domain	Ryanodine_rcpt	RYR2 RYR3	1.14e-05	3	37	2	IPR003032
Domain	Caudal_act	CDX1 CDX2	1.14e-05	3	37	2	PF04731
Domain	RR_TM4-6	RYR2 RYR3	1.14e-05	3	37	2	PF06459
Domain	Ryanrecept_TM4-6	RYR2 RYR3	1.14e-05	3	37	2	IPR009460
Domain	Caudal_activation_dom	CDX1 CDX2	1.14e-05	3	37	2	IPR006820
Domain	Ryan_recept	RYR2 RYR3	1.14e-05	3	37	2	IPR013333
Domain	-	TGIF1 CDX1 DUX4 CDX2 LHX3 HOXC12	1.80e-05	283	37	6	1.10.10.60
Domain	Homeodomain-like	TGIF1 CDX1 DUX4 CDX2 LHX3 HOXC12	4.40e-05	332	37	6	IPR009057
Domain	RIH_assoc	RYR2 RYR3	5.70e-05	6	37	2	PF08454
Domain	RIH_assoc-dom	RYR2 RYR3	5.70e-05	6	37	2	IPR013662
Domain	RYDR_ITPR	RYR2 RYR3	5.70e-05	6	37	2	PF01365
Domain	RIH_dom	RYR2 RYR3	5.70e-05	6	37	2	IPR000699
Domain	Ins145_P3_rcpt	RYR2 RYR3	5.70e-05	6	37	2	IPR014821
Domain	Ryanodine_recept-rel	RYR2 RYR3	5.70e-05	6	37	2	IPR015925
Domain	Ins145_P3_rec	RYR2 RYR3	5.70e-05	6	37	2	PF08709
Domain	-	RYR2 RYR3	5.70e-05	6	37	2	1.25.10.30
Domain	HOMEOBOX_1	TGIF1 CDX1 CDX2 LHX3 HOXC12	9.68e-05	236	37	5	PS00027
Domain	MIR	RYR2 RYR3	1.70e-04	10	37	2	PS50919
Domain	MIR	RYR2 RYR3	1.70e-04	10	37	2	PF02815
Domain	MIR	RYR2 RYR3	1.70e-04	10	37	2	SM00472
Domain	MIR_motif	RYR2 RYR3	1.70e-04	10	37	2	IPR016093
Domain	Homeobox_CS	CDX1 CDX2 LHX3 HOXC12	4.86e-04	186	37	4	IPR017970
Domain	RCC1	RCC2 NEK8	7.09e-04	20	37	2	PF00415
Domain	Homeobox_metazoa	CDX1 CDX2 HOXC12	7.47e-04	90	37	3	IPR020479
Domain	RCC1_3	RCC2 NEK8	7.83e-04	21	37	2	PS50012
Domain	RCC1_1	RCC2 NEK8	7.83e-04	21	37	2	PS00625
Domain	RCC1_2	RCC2 NEK8	7.83e-04	21	37	2	PS00626
Domain	Reg_chr_condens	RCC2 NEK8	8.60e-04	22	37	2	IPR000408
Domain	-	RCC2 NEK8	8.60e-04	22	37	2	2.130.10.30
Domain	RCC1/BLIP-II	RCC2 NEK8	9.41e-04	23	37	2	IPR009091
Domain	EF_hand_dom	PKD2L1 HRNR RYR2 RYR3	1.11e-03	232	37	4	IPR002048
Domain	Ets	FEV ERG	1.40e-03	28	37	2	PF00178
Domain	ETS_DOMAIN_1	FEV ERG	1.40e-03	28	37	2	PS00345
Domain	ETS_DOMAIN_2	FEV ERG	1.40e-03	28	37	2	PS00346
Domain	ETS	FEV ERG	1.40e-03	28	37	2	SM00413
Domain	Ets_dom	FEV ERG	1.40e-03	28	37	2	IPR000418
Domain	ETS_DOMAIN_3	FEV ERG	1.40e-03	28	37	2	PS50061
Domain	-	PKD2L1 HRNR RYR2 RYR3	1.71e-03	261	37	4	1.10.238.10
Domain	EF-hand-dom_pair	PKD2L1 HRNR RYR2 RYR3	2.42e-03	287	37	4	IPR011992
Domain	Ldl_recept_a	TMPRSS4 C1QTNF5	3.58e-03	45	37	2	PF00057
Domain	LDLRA_1	TMPRSS4 C1QTNF5	4.07e-03	48	37	2	PS01209
Domain	LDrepeatLR_classA_rpt	TMPRSS4 C1QTNF5	4.24e-03	49	37	2	IPR002172
Domain	LDLa	TMPRSS4 C1QTNF5	4.24e-03	49	37	2	SM00192
Domain	LDLRA_2	TMPRSS4 C1QTNF5	4.24e-03	49	37	2	PS50068
Pubmed	Nucleotide sequence of the partially deleted D4Z4 locus in a patient with FSHD identifies a putative gene within each 3.3 kb element.	DUX4L2 DUX4 DUX4L5 DUX4L6 DUX4L3 DUX4L4 DUX4L7 DUX4L9	2.00e-21	12	45	8	10433963
Pubmed	Evolutionary conservation of a coding function for D4Z4, the tandem DNA repeat mutated in facioscapulohumeral muscular dystrophy.	DUX4L2 DUX4 DUX4L5 DUX4L6 DUX4L3 DUX4L4 DUX4L7 DUX4L9	5.20e-21	13	45	8	17668377
Pubmed	The DUX4 gene at the FSHD1A locus encodes a pro-apoptotic protein.	DUX4L2 DUX4 DUX4L5 DUX4L6 DUX4L3 DUX4L4 DUX4L7	2.97e-20	8	45	7	17588759
Pubmed	DUX4, a candidate gene of facioscapulohumeral muscular dystrophy, encodes a transcriptional activator of PITX1.	DUX4L2 DUX4 DUX4L5 DUX4L6 DUX4L3 DUX4L4 DUX4L7	4.45e-19	10	45	7	17984056
Pubmed	Characterization of a tandemly repeated 3.3-kb KpnI unit in the facioscapulohumeral muscular dystrophy (FSHD) gene region on chromosome 4q35.	DUX4L2 DUX4 DUX4L5 DUX4L6 DUX4L3 DUX4L4 DUX4L7	6.34e-18	13	45	7	7739628
Pubmed	Active genes in junk DNA? Characterization of DUX genes embedded within 3.3 kb repeated elements.	DUX4L2 DUX4 DUX4L5 DUX4L6 DUX4L3 DUX4L4 DUX4L7	7.16e-17	17	45	7	11245978
Pubmed	Expression profiling of immature thymocytes revealed a novel homeobox gene that regulates double-negative thymocyte development.	DUX4L2 DUX4L4 DUX4L9	8.09e-09	4	45	3	17911620
Pubmed	The homeobox transcription factor DUXBL controls exit from totipotency.	DUX4L2 DUX4L4 DUX4L9	8.09e-09	4	45	3	38509386
Pubmed	Characterization of genomic structures and expression profiles of three tandem repeats of a mouse double homeobox gene: Duxbl.	DUX4L2 DUX4L4 DUX4L9	2.02e-08	5	45	3	20063414
Pubmed	The transcription factor Duxbl mediates elimination of pre-T cells that fail β-selection.	DUX4L2 DUX4L4 DUX4L9	7.06e-08	7	45	3	30765463
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	SOX15 TGIF1 DUX4L2 CDX1 CDX2 DUX4L4 NEUROG3 ZNF516 DUX4L9	7.90e-07	808	45	9	20412781
Pubmed	Proteomic analysis identifies transcriptional cofactors and homeobox transcription factors as TBX18 binding proteins.	DUX4L2 DUX4L4 DUX4L9	9.11e-07	15	45	3	30071041
Pubmed	Mutations in MINAR2 encoding membrane integral NOTCH2-associated receptor 2 cause deafness in humans and mice.	DUX4L2 DUX4L4 DUX4L9	9.11e-07	15	45	3	35727972
Pubmed	Cdx function is required for maintenance of intestinal identity in the adult.	CDX1 CDX2	1.64e-06	2	45	2	22285812
Pubmed	The homeodomain transcription factors Cdx1 and Cdx2 induce E-cadherin adhesion activity by reducing beta- and p120-catenin tyrosine phosphorylation.	CDX1 CDX2	1.64e-06	2	45	2	17463179
Pubmed	Regulation of axial elongation by Cdx.	CDX1 CDX2	1.64e-06	2	45	2	34958748
Pubmed	The mouse sino-atrial node expresses both the type 2 and type 3 Ca(2+) release channels/ryanodine receptors.	RYR2 RYR3	1.64e-06	2	45	2	14550562
Pubmed	Single nucleotide polymorphisms of caudal type homeobox 1 and 2 are associated with Barrett's esophagus.	CDX1 CDX2	1.64e-06	2	45	2	23918153
Pubmed	Differential regulation of CDX1 and CDX2 gene expression by deficiency in methyl group donors.	CDX1 CDX2	1.64e-06	2	45	2	18187048
Pubmed	A knock-in mouse model of N-terminal R420W mutation of cardiac ryanodine receptor exhibits arrhythmogenesis with abnormal calcium dynamics in cardiomyocytes.	RC3H1 RYR2	1.64e-06	2	45	2	25193700
Pubmed	Differential gene expression in normal esophagus and Barrett's esophagus.	CDX1 CDX2	1.64e-06	2	45	2	19468668
Pubmed	Defective regulation of microRNA target genes in myoblasts from facioscapulohumeral dystrophy patients.	DUX4 DUX4L9	1.64e-06	2	45	2	24145033
Pubmed	Altered ryanodine receptor expression in mild cognitive impairment and Alzheimer's disease.	RYR2 RYR3	1.64e-06	2	45	2	21531043
Pubmed	The Cdx-1 and Cdx-2 homeobox genes in the intestine.	CDX1 CDX2	1.64e-06	2	45	2	10392709
Pubmed	Modulation of calcium signalling by dominant negative splice variant of ryanodine receptor subtype 3 in native smooth muscle cells.	RYR2 RYR3	1.64e-06	2	45	2	16678258
Pubmed	Molecular cloning, sequencing and expression of the mRNA encoding human Cdx1 and Cdx2 homeobox. Down-regulation of Cdx1 and Cdx2 mRNA expression during colorectal carcinogenesis.	CDX1 CDX2	1.64e-06	2	45	2	9036867
Pubmed	Different effects of the Cdx1 and Cdx2 homeobox genes in a murine model of intestinal inflammation.	CDX1 CDX2	1.64e-06	2	45	2	17595234
Pubmed	Cdx1 and Cdx2 exhibit transcriptional specificity in the intestine.	CDX1 CDX2	1.64e-06	2	45	2	23382958
Pubmed	Cdx regulates gene expression through PRC2-mediated epigenetic mechanisms.	CDX1 CDX2	1.64e-06	2	45	2	34973175
Pubmed	Decreased expression of ryanodine receptors alters calcium-induced calcium release mechanism in mdx duodenal myocytes.	RYR2 RYR3	1.64e-06	2	45	2	14985349
Pubmed	Essential and redundant functions of caudal family proteins in activating adult intestinal genes.	CDX1 CDX2	1.64e-06	2	45	2	21402776
Pubmed	Cdx binding determines the timing of enhancer activation in postnatal duodenum.	CDX1 CDX2	1.64e-06	2	45	2	15677472
Pubmed	Deregulation of DUX4 and ERG in acute lymphoblastic leukemia.	DUX4 ERG	1.64e-06	2	45	2	27776115
Pubmed	Cdx1 and cdx2 expression during intestinal development.	CDX1 CDX2	1.64e-06	2	45	2	11040183
Pubmed	Follow-Up Study on CDX1 and CDX2 mRNA Expression in Noncancerous Gastric Mucosae After Helicobacter pylori Eradication.	CDX1 CDX2	1.64e-06	2	45	2	26841784
Pubmed	Transgenic Cdx2 induces endogenous Cdx1 in intestinal metaplasia of Cdx2-transgenic mouse stomach.	CDX1 CDX2	1.64e-06	2	45	2	19725873
Pubmed	Tissue-specific alternative splicing of mouse brain type ryanodine receptor/calcium release channel mRNA.	RYR2 RYR3	1.64e-06	2	45	2	8898078
Pubmed	[Identity and intestinal pathologies: the Cdx2 homeotic gene].	CDX1 CDX2	1.64e-06	2	45	2	23127929
Pubmed	CDX1 and CDX2 expression in intestinal metaplasia, dysplasia and gastric cancer.	CDX1 CDX2	1.64e-06	2	45	2	21532856
Pubmed	A census of human transcription factors: function, expression and evolution.	SOX15 TGIF1 FEV CDX1 CDX2 LHX3 HOXC12 ERG NEUROG3	2.07e-06	908	45	9	19274049
Pubmed	Neurogenin3 restricts serotonergic neuron differentiation to the hindbrain.	FEV LHX3 NEUROG3	2.27e-06	20	45	3	25392491
Pubmed	CDX1/2 and KLF5 Expression and Epigenetic Modulation of Sonic Hedgehog Signaling in Gastric Adenocarcinoma.	CDX1 CDX2	4.91e-06	3	45	2	30685841
Pubmed	Transformation of intestinal stem cells into gastric stem cells on loss of transcription factor Cdx2.	CDX1 CDX2	4.91e-06	3	45	2	25500896
Pubmed	Cdx1 inhibits human colon cancer cell proliferation by reducing beta-catenin/T-cell factor transcriptional activity.	CDX1 CDX2	4.91e-06	3	45	2	15215241
Pubmed	Expression of the ryanodine receptor type 3 calcium release channel during development and differentiation of mammalian skeletal muscle cells.	RYR2 RYR3	4.91e-06	3	45	2	9242641
Pubmed	cdx4/lacZ and cdx2/lacZ protein gradients formed by decay during gastrulation in the mouse.	CDX1 CDX2	4.91e-06	3	45	2	16281167
Pubmed	Type 1 and type 3 ryanodine receptors are selectively involved in muscarinic antinociception in mice: an antisense study.	RYR2 RYR3	4.91e-06	3	45	2	18403125
Pubmed	Cdx4 is a Cdx2 target gene.	CDX1 CDX2	4.91e-06	3	45	2	20933081
Pubmed	CDX transcription factors positively regulate expression of solute carrier family 5, member 8 in the colonic epithelium.	CDX1 CDX2	4.91e-06	3	45	2	19900445
Pubmed	Cdx gene deficiency compromises embryonic hematopoiesis in the mouse.	CDX1 CDX2	4.91e-06	3	45	2	18511567
Pubmed	Bidirectional coupling between ryanodine receptors and Ca2+ release-activated Ca2+ (CRAC) channel machinery sustains store-operated Ca2+ entry in human T lymphocytes.	RYR2 RYR3	4.91e-06	3	45	2	22948152
Pubmed	Cdx1 refines positional identity of the vertebrate hindbrain by directly repressing Mafb expression.	CDX1 CDX2	4.91e-06	3	45	2	21098558
Pubmed	Differential regulation of intestinal alkaline phosphatase gene expression by Cdx1 and Cdx2.	CDX1 CDX2	4.91e-06	3	45	2	15774940
Pubmed	The effect of miR-372-5p regulation on CDX1 and CDX2 in the gastric cancer cell line.	CDX1 CDX2	4.91e-06	3	45	2	36848481
Pubmed	Developmental changes in expression of the three ryanodine receptor mRNAs in the mouse brain.	RYR2 RYR3	4.91e-06	3	45	2	10788707
Pubmed	RYR2 proteins contribute to the formation of Ca(2+) sparks in smooth muscle.	RYR2 RYR3	4.91e-06	3	45	2	15024040
Pubmed	Cdx1 and Cdx2 function as tumor suppressors.	CDX1 CDX2	4.91e-06	3	45	2	25320087
Pubmed	Heterogeneous gene expression and functional activity of ryanodine receptors in resistance and conduit pulmonary as well as mesenteric artery smooth muscle cells.	RYR2 RYR3	4.91e-06	3	45	2	18434746
Pubmed	Control of Neuronal Ryanodine Receptor-Mediated Calcium Signaling by Calsenilin.	RYR2 RYR3	4.91e-06	3	45	2	29730765
Pubmed	Anterior expression of the caudal homologue cCdx-B activates a posterior genetic program in avian embryos.	CDX1 CDX2	4.91e-06	3	45	2	11500978
Pubmed	Differentiation-specific histone modifications reveal dynamic chromatin interactions and partners for the intestinal transcription factor CDX2.	CDX1 CDX2	4.91e-06	3	45	2	21074721
Pubmed	Caudal-related homeobox (Cdx) protein-dependent integration of canonical Wnt signaling on paired-box 3 (Pax3) neural crest enhancer.	CDX1 CDX2	4.91e-06	3	45	2	22457346
Pubmed	Modulation of murine embryonic stem cell-derived CD41+c-kit+ hematopoietic progenitors by ectopic expression of Cdx genes.	CDX1 CDX2	4.91e-06	3	45	2	18252864
Pubmed	Structure of the murine homeobox gene cdx-2. Expression in embryonic and adult intestinal epithelium.	CDX1 CDX2	4.91e-06	3	45	2	7910823
Pubmed	Calcineurin upregulates local Ca(2+) signaling through ryanodine receptor-1 in airway smooth muscle cells.	RYR2 RYR3	4.91e-06	3	45	2	25239916
Pubmed	Ca(2+)-induced Ca2+ release in myocytes from dyspedic mice lacking the type-1 ryanodine receptor.	RYR2 RYR3	4.91e-06	3	45	2	7621815
Pubmed	SPRY domains in ryanodine receptors (Ca(2+)-release channels).	RYR2 RYR3	4.91e-06	3	45	2	9204703
Pubmed	A gene-specific cerebral types 1, 2, and 3 RyR protein knockdown induces an antidepressant-like effect in mice.	RYR2 RYR3	4.91e-06	3	45	2	18643873
Pubmed	Identification of mutations in the cardiac ryanodine receptor gene in families affected with arrhythmogenic right ventricular cardiomyopathy type 2 (ARVD2).	RYR2 RYR3	4.91e-06	3	45	2	11159936
Pubmed	Cdx1 or Cdx2 expression activates E-cadherin-mediated cell-cell adhesion and compaction in human COLO 205 cells.	CDX1 CDX2	4.91e-06	3	45	2	14977637
Pubmed	The ryanodine receptor/calcium channel genes are widely and differentially expressed in murine brain and peripheral tissues.	RYR2 RYR3	4.91e-06	3	45	2	7876312
Pubmed	Selective activation of tumor growth-promoting Ca2+ channel MS4A12 in colon cancer by caudal type homeobox transcription factor CDX2.	CDX1 CDX2	4.91e-06	3	45	2	19781065
Pubmed	Dysregulation of CDX1, CDX2 and SOX2 in patients with gastric cancer also affects the non-malignant mucosa.	CDX1 CDX2	4.91e-06	3	45	2	23613102
Pubmed	Ryanodine receptors are expressed in epidermal keratinocytes and associated with keratinocyte differentiation and epidermal permeability barrier homeostasis.	RYR2 RYR3	4.91e-06	3	45	2	21881589
Pubmed	Regulation of the gene encoding the intestinal bile acid transporter ASBT by the caudal-type homeobox proteins CDX1 and CDX2.	CDX1 CDX2	4.91e-06	3	45	2	22016432
Pubmed	Expression of Cdx1 and Cdx2 mRNAs and relevance of this expression to differentiation in human gastrointestinal mucosa--with special emphasis on participation in intestinal metaplasia of the human stomach.	CDX1 CDX2	4.91e-06	3	45	2	11846061
Pubmed	Multiple pathways governing Cdx1 expression during murine development.	CDX1 CDX2	4.91e-06	3	45	2	11784033
Pubmed	Cdx2 Regulates Gene Expression through Recruitment of Brg1-associated Switch-Sucrose Non-fermentable (SWI-SNF) Chromatin Remodeling Activity.	CDX1 CDX2	4.91e-06	3	45	2	28082674
Pubmed	[Expression and clinical significance of caudal type homeobox transcription factor-2 in adult acute lymphocytic leukemia].	CDX1 CDX2	4.91e-06	3	45	2	21518475
Pubmed	Molecular identification of the ryanodine receptor pore-forming segment.	RYR2 RYR3	4.91e-06	3	45	2	10473538
Pubmed	Chromosomal localization of murine ryanodine receptor genes RYR1, RYR2, and RYR3 by in situ hybridization.	RYR2 RYR3	4.91e-06	3	45	2	7959768
Pubmed	Isoform-dependent formation of heteromeric Ca2+ release channels (ryanodine receptors).	RYR2 RYR3	4.91e-06	3	45	2	12213830
Pubmed	The organization of proteins in the human red blood cell membrane. A review.	RYR2 RYR3	4.91e-06	3	45	2	4600883
Pubmed	Regulation of mouse egg activation: presence of ryanodine receptors and effects of microinjected ryanodine and cyclic ADP ribose on uninseminated and inseminated eggs.	RYR2 RYR3	4.91e-06	3	45	2	7635066
Pubmed	Impact of cytosine methylation on DNA binding specificities of human transcription factors.	TGIF1 FEV CDX1 CDX2 HOXC12 ERG EGR4	5.98e-06	544	45	7	28473536
Pubmed	Requirement for the ryanodine receptor type 3 for efficient contraction in neonatal skeletal muscles.	RYR2 RYR3	9.81e-06	4	45	2	9384575
Pubmed	A glutathione deficit alters dopamine modulation of L-type calcium channels via D2 and ryanodine receptors in neurons.	RYR2 RYR3	9.81e-06	4	45	2	18206662
Pubmed	Cdx mediates neural tube closure through transcriptional regulation of the planar cell polarity gene Ptk7.	CDX1 CDX2	9.81e-06	4	45	2	21350009
Pubmed	A transcriptomic roadmap to α- and β-cell differentiation in the embryonic pancreas.	FEV NEUROG3	9.81e-06	4	45	2	31160419
Pubmed	Partial cloning and differential expression of ryanodine receptor/calcium-release channel genes in human tissues including the hippocampus and cerebellum.	RYR2 RYR3	9.81e-06	4	45	2	9607712
Pubmed	Increased Cdx protein dose effects upon axial patterning in transgenic lines of mice.	CDX1 CDX2	9.81e-06	4	45	2	18579683
Pubmed	DUX4c is up-regulated in FSHD. It induces the MYF5 protein and human myoblast proliferation.	DUX4 DUX4L9	9.81e-06	4	45	2	19829708
Pubmed	Nervous System Regionalization Entails Axial Allocation before Neural Differentiation.	CDX1 CDX2	9.81e-06	4	45	2	30343898
Pubmed	Hormonally defined pancreatic and duodenal neuroendocrine tumors differ in their transcription factor signatures: expression of ISL1, PDX1, NGN3, and CDX2.	CDX2 NEUROG3	9.81e-06	4	45	2	21739268
Pubmed	Conserved and divergent functions of Nfix in skeletal muscle development during vertebrate evolution.	RYR2 RYR3	9.81e-06	4	45	2	23482488
Pubmed	Ryanodine receptor calcium release channels: lessons from structure-function studies.	RYR2 RYR3	9.81e-06	4	45	2	23413940
Pubmed	Control of endodermal endocrine development by Hes-1.	CDX1 CDX2 NEUROG3	1.18e-05	34	45	3	10615124
Pubmed	Sorcin is an early marker of neurodegeneration, Ca2+ dysregulation and endoplasmic reticulum stress associated to neurodegenerative diseases.	RYR2 RYR3	1.63e-05	5	45	2	33060591
Pubmed	RNA transcripts, miRNA-sized fragments and proteins produced from D4Z4 units: new candidates for the pathophysiology of facioscapulohumeral dystrophy.	DUX4L2 DUX4	1.63e-05	5	45	2	19359275
Pubmed	Isx participates in the maintenance of vitamin A metabolism by regulation of beta-carotene 15,15'-monooxygenase (Bcmo1) expression.	CDX1 CDX2	1.63e-05	5	45	2	18093975
Interaction	BCL9 interactions	SOX15 FEV LHX3 ERG ALG13	4.92e-07	86	37	5	int:BCL9
Interaction	PRR12 interactions	SOX15 FEV LHX3 ERG ALG13	5.53e-07	88	37	5	int:PRR12
Interaction	KMT2D interactions	SOX15 FEV LHX3 ERG POLR2A ALG13	5.96e-07	169	37	6	int:KMT2D
Interaction	ZNF703 interactions	SOX15 FEV ERG BAG4 ALG13	7.28e-07	93	37	5	int:ZNF703
Interaction	FOXP4 interactions	SOX15 FEV LHX3 ERG FUBP1	9.45e-07	98	37	5	int:FOXP4
Interaction	TLE1 interactions	SOX15 FEV LHX3 ERG FUBP1 ALG13	2.30e-06	213	37	6	int:TLE1
Interaction	ZNF609 interactions	SOX15 FEV LHX3 ERG ALG13	6.74e-06	146	37	5	int:ZNF609
Interaction	ATXN1L interactions	SOX15 FEV LHX3 ERG ALG13	7.69e-06	150	37	5	int:ATXN1L
Interaction	GSE1 interactions	SOX15 FEV LHX3 ERG ALG13	8.74e-06	154	37	5	int:GSE1
Interaction	ARID1B interactions	SOX15 FEV LHX3 ERG ALG13	1.71e-05	177	37	5	int:ARID1B
Interaction	MNX1 interactions	SOX15 FEV LHX3	1.81e-05	28	37	3	int:MNX1
Interaction	ZNF608 interactions	SOX15 FEV ERG ALG13	2.50e-05	93	37	4	int:ZNF608
Interaction	DPF1 interactions	SOX15 FEV LHX3 ERG	2.72e-05	95	37	4	int:DPF1
Interaction	EP300 interactions	NELFE SOX15 FEV DUX4 CDX2 ERG ANK1 COPS6 RCC2 POLR2A ALG13	2.79e-05	1401	37	11	int:EP300
Interaction	SS18L1 interactions	FEV LHX3 ERG BAG4	3.07e-05	98	37	4	int:SS18L1
Interaction	LDB1 interactions	SOX15 FEV LHX3 ERG	5.75e-05	115	37	4	int:LDB1
Interaction	FOXC1 interactions	NELFE SOX15 FEV RCC2 FUBP1	5.76e-05	228	37	5	int:FOXC1
Interaction	SIX4 interactions	SOX15 FEV LHX3	8.19e-05	46	37	3	int:SIX4
Interaction	ALX4 interactions	SOX15 CDX1 CDX2	9.31e-05	48	37	3	int:ALX4
Interaction	FOXP1 interactions	SOX15 FEV LHX3 ERG FUBP1	9.94e-05	256	37	5	int:FOXP1
Interaction	NCOR2 interactions	SOX15 FEV LHX3 ERG ALG13	1.15e-04	264	37	5	int:NCOR2
Interaction	PRRC2B interactions	FEV ERG RC3H1 BAG4 ALG13	1.17e-04	265	37	5	int:PRRC2B
Interaction	PHF10 interactions	FEV CDX2 LHX3 NEUROG3	1.20e-04	139	37	4	int:PHF10
Interaction	NCOA2 interactions	SOX15 FEV ERG ALG13	1.27e-04	141	37	4	int:NCOA2
Interaction	NFIB interactions	SOX15 FEV LHX3 ERG	1.30e-04	142	37	4	int:NFIB
Interaction	TRPS1 interactions	SOX15 FEV LHX3 ERG	1.34e-04	143	37	4	int:TRPS1
Interaction	ARID1A interactions	SOX15 FEV LHX3 ERG ALG13	1.41e-04	276	37	5	int:ARID1A
Interaction	TCF20 interactions	FEV LHX3 ERG ALG13	1.45e-04	146	37	4	int:TCF20
Interaction	DDX3X interactions	DUX4 HRNR ERG COPS6 FUBP1 RC3H1 ALG13	1.57e-04	651	37	7	int:DDX3X
Interaction	CIC interactions	SOX15 FEV LHX3 HRNR ERG RCC2 POLR2A	1.93e-04	673	37	7	int:CIC
Interaction	SATB2 interactions	SOX15 FEV LHX3 ERG	2.01e-04	159	37	4	int:SATB2
Interaction	KDM2B interactions	FEV LHX3 ERG ALG13	2.11e-04	161	37	4	int:KDM2B
Interaction	BCOR interactions	SOX15 FEV LHX3 ERG ALG13	2.15e-04	302	37	5	int:BCOR
Interaction	KDM6A interactions	SOX15 FEV LHX3 ERG	2.16e-04	162	37	4	int:KDM6A
Interaction	ZHX2 interactions	SOX15 FEV LHX3	2.75e-04	69	37	3	int:ZHX2
Interaction	CYTOR interactions	HRNR RCC2	2.94e-04	14	37	2	int:CYTOR
Interaction	XRCC5 interactions	DUX4 CDX2 ERG FUBP1 RC3H1 POLR2A	3.21e-04	515	37	6	int:XRCC5
Interaction	ZFHX4 interactions	FEV LHX3 ERG	3.24e-04	73	37	3	int:ZFHX4
Interaction	MORC4 interactions	FEV LHX3 ERG	3.38e-04	74	37	3	int:MORC4
Interaction	C15orf39 interactions	FEV ERG ALG13	3.38e-04	74	37	3	int:C15orf39
Interaction	NFIA interactions	SOX15 FEV LHX3 ERG	3.81e-04	188	37	4	int:NFIA
Interaction	EHMT1 interactions	SOX15 FEV CDX2 LHX3	3.81e-04	188	37	4	int:EHMT1
Interaction	KIR2DS5 interactions	COPS6 FUBP1	3.87e-04	16	37	2	int:KIR2DS5
Interaction	SMARCA2 interactions	CDX2 LHX3 ERG FUBP1 POLR2A	4.02e-04	346	37	5	int:SMARCA2
Interaction	SNRPD1 interactions	NELFE COPS6 RCC2 RC3H1 POLR2A	4.08e-04	347	37	5	int:SNRPD1
Interaction	DPF2 interactions	SOX15 FEV LHX3 ERG COPS6	4.18e-04	349	37	5	int:DPF2
Interaction	HNRNPUL1 interactions	SOX15 ERG COPS6 FUBP1 RC3H1	4.29e-04	351	37	5	int:HNRNPUL1
Interaction	ZNF281 interactions	SOX15 FEV ERG NEUROG3	4.54e-04	197	37	4	int:ZNF281
Interaction	NR2C1 interactions	SOX15 FEV LHX3	4.90e-04	84	37	3	int:NR2C1
Interaction	RING1 interactions	FEV LHX3 ERG ALG13	4.90e-04	201	37	4	int:RING1
Interaction	NCOR1 interactions	NELFE FEV LHX3 ERG ALG13	5.00e-04	363	37	5	int:NCOR1
Interaction	NCL interactions	NELFE DUX4 ERG COPS6 RC3H1 RYR2 POLR2A	5.41e-04	798	37	7	int:NCL
Interaction	NFIC interactions	SOX15 FEV LHX3 ERG	5.78e-04	210	37	4	int:NFIC
Interaction	UPF1 interactions	SOX15 CDX1 FUBP1 RC3H1 POLR2A ALG13	6.08e-04	581	37	6	int:UPF1
Interaction	ZEB2 interactions	FEV LHX3 COPS6	7.02e-04	95	37	3	int:ZEB2
Interaction	BCL7B interactions	FEV LHX3 ERG	7.02e-04	95	37	3	int:BCL7B
Interaction	DNTTIP1 interactions	SOX15 FEV ERG	7.02e-04	95	37	3	int:DNTTIP1
Interaction	CREBBP interactions	FEV DUX4 CDX2 LHX3 ERG POLR2A	7.13e-04	599	37	6	int:CREBBP
Interaction	ZNF326 interactions	CDX2 FUBP1 RC3H1 POLR2A	7.36e-04	224	37	4	int:ZNF326
Interaction	NCOA3 interactions	SOX15 FEV ERG ALG13	7.36e-04	224	37	4	int:NCOA3
Interaction	PCIF1 interactions	NELFE POLR2A	7.40e-04	22	37	2	int:PCIF1
Interaction	PBX2 interactions	FEV HOXC12 COPS6	7.46e-04	97	37	3	int:PBX2
Interaction	HNRNPF interactions	NELFE DUX4 ERG COPS6 RC3H1 POLR2A	7.64e-04	607	37	6	int:HNRNPF
Interaction	FBRS interactions	FEV ERG ALG13	8.63e-04	102	37	3	int:FBRS
Interaction	RYR3 interactions	RYR2 RYR3	8.82e-04	24	37	2	int:RYR3
Interaction	PSMB5 interactions	FEV ERG RCC2 BAG4	9.81e-04	242	37	4	int:PSMB5
Interaction	HNRNPD interactions	NELFE ERG COPS6 FUBP1 RC3H1 POLR2A	9.90e-04	638	37	6	int:HNRNPD
Interaction	MIDEAS interactions	FEV LHX3 ERG	1.02e-03	108	37	3	int:MIDEAS
Cytoband	4q35.2	DUX4L2 DUX4L5 DUX4L6 DUX4L3 DUX4L4 DUX4L7	1.83e-13	27	45	6	4q35.2
Cytoband	Ensembl 112 genes in cytogenetic band chr4q35	DUX4L2 DUX4 DUX4L5 DUX4L6 DUX4L3 DUX4L4 DUX4L7 DUX4L9	2.78e-13	117	45	8	chr4q35
Cytoband	Xq23	RBMXL3 ALG13	1.21e-03	52	45	2	Xq23
Cytoband	11q23.3	TMPRSS4 C1QTNF5	2.69e-03	78	45	2	11q23.3
Cytoband	Ensembl 112 genes in cytogenetic band chrXq23	RBMXL3 ALG13	3.48e-03	89	45	2	chrXq23
Cytoband	Ensembl 112 genes in cytogenetic band chr8p11	ANK1 BAG4	4.63e-03	103	45	2	chr8p11
GeneFamily	PRD class homeoboxes and pseudogenes	DUX4L2 DUX4L5 DUX4L6 DUX4L3 DUX4L4 DUX4L7 DUX4L9	6.37e-10	92	37	7	521
GeneFamily	Ryanodine receptors\|Protein phosphatase 1 regulatory subunits	RYR2 RYR3	1.22e-05	3	37	2	287
GeneFamily	HOXL subclass homeoboxes	CDX1 CDX2 HOXC12	1.63e-04	52	37	3	518
GeneFamily	ETS transcription factor family	FEV ERG	1.49e-03	28	37	2	534
GeneFamily	EF-hand domain containing	HRNR RYR2 RYR3	1.01e-02	219	37	3	863
GeneFamily	Basic helix-loop-helix proteins	NEUROG3 NPAS4	2.13e-02	110	37	2	420
Coexpression	MEISSNER_BRAIN_HCP_WITH_H3K27ME3	FEV CDX1 CDX2 LHX3 HOXC12 RBMXL3 NEUROG3	3.58e-07	282	43	7	MM822
Coexpression	BENPORATH_ES_WITH_H3K27ME3	FEV CDX1 CDX2 LHX3 C1QTNF5 HOXC12 EGR4 VGLL2 NEUROG3 NPAS4 RYR3	1.29e-06	1115	43	11	M10371
Coexpression	MIKKELSEN_MEF_HCP_WITH_H3K27ME3	FEV CDX1 CDX2 LHX3 ADRA2C RBMXL3 NEUROG3 RYR2	5.21e-06	601	43	8	MM866
Coexpression	MEISSNER_BRAIN_HCP_WITH_H3K27ME3	FEV CDX1 CDX2 LHX3 HOXC12 NEUROG3	5.22e-06	272	43	6	M1938
Coexpression	MIKKELSEN_MCV6_HCP_WITH_H3K27ME3	FEV LHX3 ADRA2C HOXC12 ANK1 VGLL2 NEUROG3	6.65e-06	438	43	7	M1954
Coexpression	MIKKELSEN_MCV6_HCP_WITH_H3K27ME3	FEV LHX3 ADRA2C HOXC12 ANK1 VGLL2 NEUROG3	6.85e-06	440	43	7	MM832
Coexpression	MIKKELSEN_NPC_HCP_WITH_H3K27ME3	FEV CDX2 ADRA2C VGLL2 NEUROG3 RYR2	2.01e-05	345	43	6	M2009
Coexpression	MIKKELSEN_NPC_HCP_WITH_H3K27ME3	FEV CDX2 ADRA2C VGLL2 NEUROG3 RYR2	2.08e-05	347	43	6	MM860
Coexpression	MIKKELSEN_MEF_HCP_WITH_H3K27ME3	FEV CDX1 CDX2 LHX3 ADRA2C NEUROG3 RYR2	4.55e-05	591	43	7	M2019
Coexpression	BENPORATH_PRC2_TARGETS	FEV CDX2 HOXC12 EGR4 NEUROG3 NPAS4 RYR3	8.28e-05	650	43	7	M8448
Coexpression	GSE6092_CTRL_VS_BORRELIA_BIRGDOFERI_INF_ENDOTHELIAL_CELL_DN	TGIF1 LHX3 EGR4 NEK8	1.04e-04	149	43	4	M6708
Coexpression	DESCARTES_MAIN_FETAL_ISLET_ENDOCRINE_CELLS	FEV EGR4 NEUROG3	2.09e-04	70	43	3	M40128
Coexpression	BENPORATH_SUZ12_TARGETS	FEV CDX2 HOXC12 ERG EGR4 NEUROG3 NPAS4 RYR3	2.44e-04	1035	43	8	M9898
Coexpression	BENPORATH_EED_TARGETS	FEV CDX2 HOXC12 EGR4 VGLL2 NEUROG3 NPAS4 RYR3	2.85e-04	1059	43	8	M7617
Coexpression	MEISSNER_NPC_HCP_WITH_H3K27ME3	CDX2 HOXC12 NEUROG3	2.98e-04	79	43	3	M1932
Coexpression	MEISSNER_NPC_HCP_WITH_H3K27ME3	CDX2 HOXC12 NEUROG3	3.09e-04	80	43	3	MM817
Coexpression	GSE7460_FOXP3_MUT_VS_HET_ACT_TCONV_DN	COPS6 EGR4 NPAS4 BAG4	3.16e-04	199	43	4	M5707
ToppCell	Cerebellum-Neuronal-Excitatory\|Cerebellum / BrainAtlas - Mouse McCarroll V32	GSG1L GPR25 EGR4 RYR3	4.76e-06	128	39	4	c30ba14320e9b98c9af9e4cd5a8c55380bb9ffa9
ToppCell	facs-Heart-RA-24m-Mesenchymal-atrial_myocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GSG1L ANK1 RYR2 RYR3	1.07e-05	157	39	4	9021900d9b1a71210c9c414a9d165eaf399eb607
ToppCell	facs-Heart-RA-24m-Mesenchymal-atrial_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GSG1L ANK1 RYR2 RYR3	1.07e-05	157	39	4	c8c627ca181856cd31dba4cf073c2be659a49dc1
ToppCell	COVID-19-Heart-T_cell\|COVID-19 / Disease (COVID-19 only), tissue and cell type	DUX4 GSG1L ANK1 RYR3	1.49e-05	171	39	4	b2e753e811a7639956994609f73efcdb62d04f82
ToppCell	3'-Adult-LargeIntestine-Epithelial-neuro-epithelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FEV EGR4 NEUROG3 NPAS4	1.79e-05	179	39	4	f93e81a3fd94adedb24a9db4ac1d53e275bbf8b5
ToppCell	3'-Adult-LargeIntestine-Epithelial-neuro-epithelial-L_cells_(PYY+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FEV EGR4 NEUROG3 NPAS4	1.95e-05	183	39	4	49f3ddc1c7c04b4ca837dbd6dad995add82941d6
ToppCell	Striatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Drd1-Excitatory_Neuron.Gad1Gad2.Drd1-Cxcl14_(dSPN,_lateral_striatum)-\|Striatum / BrainAtlas - Mouse McCarroll V32	TMPRSS4 LHX3 VGLL2	1.99e-05	60	39	3	b3941f8c3cf2365c5bf79961f62c9c0c7405a67b
ToppCell	Striatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Drd1-Excitatory_Neuron.Gad1Gad2.Drd1-Cxcl14_(dSPN,_lateral_striatum)\|Striatum / BrainAtlas - Mouse McCarroll V32	TMPRSS4 LHX3 VGLL2	1.99e-05	60	39	3	64d4de1de20d07c5f2e20b76854311a31718faa4
ToppCell	facs-Heart-LA-24m-Mesenchymal-ventricular_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GSG1L ANK1 NPAS4 RYR2	2.08e-05	186	39	4	337f768cc43db2db96ba6495b076006b1a5b0331
ToppCell	droplet-Liver-LIVER_HEP-30m-Lymphocytic-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FEV EGR4 NPAS4 BAG4	2.08e-05	186	39	4	f5468e03321ea2083e223eb0d92c3a9307039569
ToppCell	facs-Heart-LA-24m-Mesenchymal-ventricular_myocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GSG1L ANK1 NPAS4 RYR2	2.08e-05	186	39	4	e378c82ef6d6cb24751515aa499a01372b3e7ccf
ToppCell	facs-Heart-RA-24m-Mesenchymal-ventricular_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GSG1L ANK1 RYR2 RYR3	2.21e-05	189	39	4	b98f60875b1a12b2ec9dc91889298ae57f98602f
ToppCell	facs-Heart-RA-24m-Mesenchymal-ventricular_myocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GSG1L ANK1 RYR2 RYR3	2.21e-05	189	39	4	e758b264c0a47127e33e66c395cf5a3224c7305b
ToppCell	droplet-Limb_Muscle-nan-24m-Mesenchymal-skeletal_muscle_satellite_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TGIF1 ANK1 VGLL2 RYR3	2.65e-05	198	39	4	d5e91d1057e71b6a336eec95e44b2e7fe6b2c6ef
ToppCell	Parenchymal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_systemic_arterial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ADRA2C ERG ANK1 RYR2	2.71e-05	199	39	4	b768496381362f9a2706e0892b5a7a0db82e09ce
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L5_PT-L5_PT_VISp_C1ql2_Ptgfr\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ERG EGR4 RYR3	1.86e-04	127	39	3	fb58f4b4d3722f4b9a2e4946c0244c5b70dd883b
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L5_PT-L5_PT_VISp_C1ql2_Cdh13\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ERG EGR4 RYR3	2.28e-04	136	39	3	1f3000d5f105c87c80f8ae1dd2264bcd7f757a9c
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L5_PT\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ERG EGR4 RYR3	2.48e-04	140	39	3	7cc891d676555609add6fc7880735d948a2ad801
ToppCell	Control-Epithelial-PNEC\|World / Disease state, Lineage and Cell class	HOXC12 EGR4 NPAS4	2.98e-04	149	39	3	02b47193621d23a50378d7905d7f85aaab686cfb
ToppCell	Control-Epithelial-PNEC\|Epithelial / Disease state, Lineage and Cell class	HOXC12 EGR4 NPAS4	3.10e-04	151	39	3	25e7a42989faa01cd41f45b8563725556a5b0cab
ToppCell	facs-Aorta-Heart-3m-Mesenchymal-valve_cells\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LHX3 GSG1L NEUROG3	3.22e-04	153	39	3	1440f2716fea74e2c3eb2924eba3d63ebd08c997
ToppCell	TCGA-Bone_and_Soft_Tissue-Primary_Tumor-Sarcoma-Conventional_Leiomyosarcoma\|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9	NPAS4 RYR2 RYR3	3.22e-04	153	39	3	ec6fe6b8c884fa76adc7a0f9db041f7b1567a2ee
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_PP_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FEV EGR4 POLR2A	3.28e-04	154	39	3	2d98bb7a784fc3215e0d4a1670d662e5df4716c3
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_PP_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FEV EGR4 POLR2A	3.28e-04	154	39	3	0dec222101530f1727184dbb7c03969d3884f111
ToppCell	droplet-Fat-Mat-18m-Epithelial-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMPRSS4 CDX1 CDX2	3.41e-04	156	39	3	f09150aacb6121f913648ed3918f9cd4f22c61f2
ToppCell	droplet-Fat-Mat-18m-Epithelial\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMPRSS4 CDX1 CDX2	3.41e-04	156	39	3	cfd7f56f3155db677684827607e9008e975dbe70
ToppCell	droplet-Fat-Mat-18m-Epithelial-epithelial_cell\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMPRSS4 CDX1 CDX2	3.41e-04	156	39	3	0d79b4172896574b00faf00e87254f68d76f5512
ToppCell	Posterior_cortex\|World / BrainAtlas - Mouse McCarroll V32	EGR4 NPAS4 RYR2	3.60e-04	159	39	3	18e9fe2efbe0bca7c3990f3b12b6f549e2c1263a
ToppCell	facs-SCAT-Fat-18m-Epithelial-epithelial_cell\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMPRSS4 CDX1 CDX2	3.81e-04	162	39	3	7215f6eb2b65dea455e2eec722a9c38e6958b120
ToppCell	facs-SCAT-Fat-18m-Epithelial-nan\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMPRSS4 CDX1 CDX2	3.81e-04	162	39	3	7fa93efa2039d68a4e8214fa143bcd3368349a2d
ToppCell	facs-SCAT-Fat-18m-Epithelial\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMPRSS4 CDX1 CDX2	3.81e-04	162	39	3	341fa357ad7bdbef30864e8062f161e60185ffc9
ToppCell	COVID-19-kidney-Technical/muscle_(Imm)\|kidney / Disease (COVID-19 only), tissue and cell type	DUX4 GSG1L RYR2	3.88e-04	163	39	3	19c28ce16a588a7f4a035c32726f6ccd67702b5b
ToppCell	10x5'-lymph-node_spleen-Hematopoietic_progenitors-Progenitor\|lymph-node_spleen / Manually curated celltypes from each tissue	CDX2 ERG MTSS2	4.02e-04	165	39	3	7b992843bd8ef92a7a76b1d681fa84efde6f5bdd
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L4-5_RORB_AIM2\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FEV ERG RYR3	4.16e-04	167	39	3	4c8bb68ee2bf7b794940b34df96f38f3f69507e9
ToppCell	facs-GAT-Fat-18m-Epithelial\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMPRSS4 CDX1 CDX2	4.23e-04	168	39	3	d6c8056b7d6b937bb91e6b33beeb1075dce1685c
ToppCell	facs-GAT-Fat-18m-Epithelial-epithelial_cell\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMPRSS4 CDX1 CDX2	4.23e-04	168	39	3	7102c52bf1b2ba67bb3700932181a2e0a6627711
ToppCell	facs-GAT-Fat-18m-Epithelial-nan\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMPRSS4 CDX1 CDX2	4.23e-04	168	39	3	68a2f9fd53b54023241acd1620cf24226f639c1b
ToppCell	Adult-Endothelial-endothelial_cell_of_artery-D122\|Adult / Lineage, Cell type, age group and donor	ADRA2C ERG RYR3	4.23e-04	168	39	3	8c3e1e45b422813bcdfa4273b1167db649a312f5
ToppCell	3'-GW_trimst-2-LargeIntestine-Epithelial-neuro-epithelial\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FEV EGR4 NEUROG3	4.23e-04	168	39	3	38ba7737ae0afffcbd3aa499403e83c24a922127
ToppCell	facs-Heart-LA-18m-Myeloid-macrophage\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMPRSS4 CDX1 CDX2	4.31e-04	169	39	3	421fb287c7e439d1870b7950c5e3ca34106e014a
ToppCell	facs-Diaphragm-Limb_Muscle-24m\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RYR2 POLR2A RYR3	4.31e-04	169	39	3	12bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCell	facs-Heart-LA-18m-Myeloid-macrophage\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMPRSS4 CDX1 CDX2	4.31e-04	169	39	3	383639ec4f9d0c6255e0881edca15cdd1980a37c
ToppCell	PND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ANK1 NPAS4 RYR2	4.38e-04	170	39	3	da4fb1e186e9bec6bba0b25f2a0e68f9e11c6017
ToppCell	PND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ANK1 NPAS4 RYR2	4.38e-04	170	39	3	cb1ed6bd409ee1cf11be0d5e7cdcffe2ab220d38
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Epithelial-Tuft-related\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TMPRSS4 CDX1 CDX2	4.46e-04	171	39	3	042701dd87676d41d8e7e7cce0e1ffc2331b248d
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Epithelial-Tuft-related-BEST4+_epithelial\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TMPRSS4 CDX1 CDX2	4.46e-04	171	39	3	74d7811a57837d99932a9b86f2d08e8574a819e6
ToppCell	T_cells-CD56_bright_CD16-_NK_cells\|World / Immune cells in Kidney/Urine in Lupus Nephritis	HRNR ERG RYR3	4.53e-04	172	39	3	980e8b9e1ceeb0dec9eb9ef95c139e5ffe99b6e4
ToppCell	facs-Heart-Unknown-3m-Mesenchymal-atrial_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HRNR ANK1 RYR2	4.53e-04	172	39	3	bd468a7ea6ec832dcf6a816a1e0c03fa0f176dad
ToppCell	facs-Heart-Unknown-3m-Mesenchymal-atrial_myocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HRNR ANK1 RYR2	4.53e-04	172	39	3	ee8ce9e8c9a6d3ee2be113f77743958005f4b3f0
ToppCell	droplet-Thymus-nan-18m-Lymphocytic-DN3_thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TGIF1 ERG GPR25	4.61e-04	173	39	3	5d7c53c6d1cdd385e44b79b82faec901747d1736
ToppCell	droplet-Thymus-nan-18m-Lymphocytic-Double_negative_thymocyte,_DN3_(Cd8-,_Cd4-),_some_express_pre_TCR_alpha\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TGIF1 ERG GPR25	4.69e-04	174	39	3	9eab43885496b8586f8ec5b4bcb1fd5b209218e5
ToppCell	droplet-Heart-4Chambers-21m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GSG1L ANK1 RYR2	4.69e-04	174	39	3	f098778ea74012861ec74b425e45776a31f67679
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Neuronal-interneuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDX1 ANK1 RYR2	4.77e-04	175	39	3	65571d775d26a40e979dbf290a8e4320c0d9fb3f
ToppCell	3'-Child09-12-SmallIntestine-Epithelial-epithelial_progenitor_cell-Stem_cells\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TGIF1 CDX1 CDX2	4.77e-04	175	39	3	0431897d7fcc9cefb516cd36987cf18b7f19a26a
ToppCell	3'-Pediatric_IBD-SmallIntestine-Epithelial-neuro-epithelial\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FEV GSG1L HRNR	4.85e-04	176	39	3	fb718a6b07aa5d56600263280afa530bcb63db42
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Epithelial-epithelial_progenitor_cell-TA\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TMPRSS4 CDX1 CDX2	4.85e-04	176	39	3	e7502a345b2da83a9a60f50cf78f1aef385c99df
ToppCell	facs-Marrow-B-cells-3m-Lymphocytic-early_pro_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX15 GSG1L ERG	4.85e-04	176	39	3	29cda51a99100ddd2928cadc92da40f001d7e1f4
ToppCell	droplet-Thymus-nan-21m-Lymphocytic-DN3_thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX15 TMPRSS4 GPR25	4.85e-04	176	39	3	d43d9e86c4d4fa1e88fbf2b899ac7143717aac90
ToppCell	facs-Marrow-B-cells-3m-Lymphocytic-early_pro-B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX15 GSG1L ERG	4.85e-04	176	39	3	01774a86d7d92f31a056b753f9844f923038003e
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Epithelial-neuro-epithelial-EECs\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FEV CDX1 NEUROG3	4.93e-04	177	39	3	5bccc7a74019eae8afd977a9c9134d884857ac27
ToppCell	facs-Trachea-24m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l6-17\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ANK1 EGR4 NPAS4	4.93e-04	177	39	3	8abdf1d970b2f15e17e185f3e612dd5065c88757
ToppCell	facs-Brain_Myeloid-Cortex-24m-Myeloid\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FEV CDX1 CDX2	5.09e-04	179	39	3	bc93883c2094f2e5bfed79facd4994a23968d875
ToppCell	facs-Brain_Myeloid-Cortex-24m-Myeloid-microglial_cell\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FEV CDX1 CDX2	5.09e-04	179	39	3	0cef6d2eab2015cac0dd340532b24bfec9707330
ToppCell	10x5'v1-week_17-19-Hematopoietic-erythroid-early_erythroid\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	TMPRSS4 ANK1 RYR3	5.09e-04	179	39	3	3f73f89905c061ada4e3eb921fa394d95f95c959
ToppCell	droplet-Lung-21m-Hematologic-myeloid-myeloid_dendritic_cell-Ccr7+_dendritic\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TGIF1 GPR25 RYR3	5.09e-04	179	39	3	4f20540bfbcefe0e83812be7ea542e8bb3bf19bc
ToppCell	facs-Brain_Myeloid-Cortex-24m\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FEV CDX1 CDX2	5.09e-04	179	39	3	bb2410b3934fcc53396b96b48e0d9843df159b89
ToppCell	droplet-Lung-nan-21m-Myeloid-Ccr7+_Dendritic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TGIF1 GPR25 RYR3	5.09e-04	179	39	3	d78eacf47847a50888dd16c35bed9b7afc80010f
ToppCell	facs-Brain_Myeloid-Cortex-24m-Myeloid-nan\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FEV CDX1 CDX2	5.09e-04	179	39	3	065241799cea30da62cb3b6f2f1970bd1b0f4e2b
ToppCell	3'-GW_trimst-1-SmallIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FEV LHX3 NEUROG3	5.09e-04	179	39	3	ec7c38464863ac3744a8d4880f49421914892339
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Epithelial-epithelial_progenitor_cell-Proximal_progenitor\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TMPRSS4 CDX1 CDX2	5.18e-04	180	39	3	8d9be9cfdf98e5888654a28ab12e5e89f201af00
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Epithelial-Tuft-related\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TMPRSS4 CDX1 CDX2	5.18e-04	180	39	3	156b988b71f6dcf3117c1e5f4625632cb97e54f2
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Epithelial-Tuft-related-BEST4+_epithelial\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TMPRSS4 CDX1 CDX2	5.18e-04	180	39	3	d1beaf1f106c7efaeaf61f29742d0a7310a83916
ToppCell	facs-Heart-RA-24m-Myeloid-macrophage\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX15 TMPRSS4 TGIF1	5.26e-04	181	39	3	c68d272eb41f81bd8ea4d0360733a2396bc87037
ToppCell	facs-Heart-RA-24m-Myeloid-macrophage\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX15 TMPRSS4 TGIF1	5.26e-04	181	39	3	5e5eb89f224ee48065a328ade030cbc4dcdcac12
ToppCell	droplet-Heart-4Chambers-21m-Neuronal-nan\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX15 PKD2L1 TMPRSS4	5.26e-04	181	39	3	3fd16229a63de0971db5d48860c01173d7db518f
ToppCell	facs\|World / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMPRSS4 CDX1 POLR2A	5.35e-04	182	39	3	08f775135b451be709f5fc8e1cbcf63425794a2e
ToppCell	facs-Brain_Non-Myeloid-Striatum_-18m-Neuronal-SPN_Neuron_STR\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADRA2C EGR4 RYR3	5.43e-04	183	39	3	9533db4db2c6ae78d7ca1682cf4efed12183396f
ToppCell	droplet-Large_Intestine\|droplet / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMPRSS4 CDX1 CDX2	5.43e-04	183	39	3	9d7ffcb9804b9a52448ccb56c9370b317a4b52a5
ToppCell	facs-Brain_Non-Myeloid-Striatum_-18m-Neuronal-medium_spiny_neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADRA2C EGR4 RYR3	5.43e-04	183	39	3	bf7f1cb55ed55981b8b355d5774055c96e658ff2
ToppCell	droplet-Heart-4Chambers-21m-Neuronal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX15 PKD2L1 TMPRSS4	5.43e-04	183	39	3	a046b569bc10083d471b420eb2c6fee93437602d
ToppCell	droplet-Heart-4Chambers-21m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX15 PKD2L1 TMPRSS4	5.43e-04	183	39	3	4de2082dca2569d3aac3c9b466f27971c82d302b
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb-24m-Mesenchymal-skeletal_muscle_satellite_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TGIF1 CDX1 VGLL2	5.43e-04	183	39	3	7534587fa35837c0aaca93c542f2eee493eba637
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANK1 RYR2 RYR3	5.52e-04	184	39	3	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	10x5'v1-week_17-19-Hematopoietic-erythroid\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	TMPRSS4 ANK1 RYR3	5.52e-04	184	39	3	0efc757d9512d6a8fe8176e977a94e4494ed9778
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANK1 RYR2 RYR3	5.52e-04	184	39	3	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANK1 RYR2 RYR3	5.52e-04	184	39	3	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	droplet-Limb_Muscle-Pre-Sort-18m-Mesenchymal-skeletal_muscle_satellite_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TGIF1 ANK1 VGLL2	5.61e-04	185	39	3	5414a66169c39d09a67b1050aad5e61f46b3749a
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GSG1L ANK1 RYR2	5.61e-04	185	39	3	cdd75abdaa1ecedfd2e636203b83a6ac1782f0c3
ToppCell	Control-Epithelial-Basal\|Epithelial / Disease state, Lineage and Cell class	SOX15 TMPRSS4 ERG	5.61e-04	185	39	3	d5d6d13e2f20b54ca55645b9a757b8599f4fd897
ToppCell	droplet-Limb_Muscle-nan-21m-Mesenchymal-skeletal_muscle_satellite_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TGIF1 ANK1 VGLL2	5.69e-04	186	39	3	1cbb1a1c4f0f6078e9c7b4e0dc93d6b6de7e57db
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RCC2 POLR2A MTSS2	5.69e-04	186	39	3	bd1185592aedebccd1007dbf2dd2f549fcdf9f42
ToppCell	droplet-Kidney-nan-21m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EGR4 RYR2 BAG4	5.69e-04	186	39	3	8eafd4bea692f7ef33de27dd53f9d1fe67deaad8
ToppCell	Adult-Endothelial-endothelial_cell_of_artery\|Adult / Lineage, Cell type, age group and donor	ADRA2C ERG RYR3	5.69e-04	186	39	3	2d1c4ea2e401db89971582ee54618a8b0c81b8ac
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Epithelial-mature_enterocytic-Colonocyte\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TMPRSS4 CDX1 CDX2	5.78e-04	187	39	3	1909b65ba23d598e396f77eecae562bb59bf5d5d
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GSG1L ANK1 RYR2	5.78e-04	187	39	3	7b2cd0c618ed081223343f3bec2244c8723c9a31
ToppCell	3'-GW_trimst-1-SmallIntestine-Epithelial-neuro-epithelial-EECs\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FEV CDX2 NEUROG3	5.87e-04	188	39	3	ed074572e61d97c139fb1636a78c9b71e2c44ce0
ToppCell	facs-Heart-RA-24m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GSG1L RYR2 RYR3	5.97e-04	189	39	3	e4efbb0733b382f4c855f6653dcddf36e0f8df28
ToppCell	Mesenchymal_cells-Myofibroblasts\|Mesenchymal_cells / Lineage and Cell class	TGIF1 ANK1 VGLL2	5.97e-04	189	39	3	f5322429963257cfd3fd813d7b7d273d3d12d622
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ERG NPAS4 RYR2	5.97e-04	189	39	3	2cfb4d12f75678d1619f4743838a0e954bd57761
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Epithelial-mature_enterocytic\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TMPRSS4 CDX1 CDX2	5.97e-04	189	39	3	8478f433495dabe813146a1f6b00098db8ce775a
Computational	Genes in the cancer module 123.	TGIF1 CDX1 ERG EGR4 ZNF516	7.19e-05	247	20	5	MODULE_123
Drug	AC1MW7VF	SMPD1 RYR2 RYR3	6.39e-06	19	44	3	CID000414699
Drug	2-hydroxyheptanoic acid	RYR2 RYR3	1.09e-05	3	44	2	CID002750949
Drug	Ryanodyl 3-(pyridine-3-carboxylate	RYR2 RYR3	1.09e-05	3	44	2	CID005748312
Drug	8N3-cADPR	RYR2 RYR3	1.09e-05	3	44	2	CID000127713
Drug	2-hydroxycarbazole	RYR2 RYR3	1.09e-05	3	44	2	CID000093551
Drug	aminodantrolene	RYR2 RYR3	1.09e-05	3	44	2	CID009570289
Drug	cis-diammineplatinum(II	RYR2 RYR3	1.09e-05	3	44	2	CID000159790
Drug	SC 38249	RYR2 RYR3	2.18e-05	4	44	2	CID000134834
Drug	AC1L1U7A	RYR2 RYR3	2.18e-05	4	44	2	CID000035682
Drug	PCB74	RYR2 RYR3	2.18e-05	4	44	2	CID000036218
Drug	148504-47-6	RYR2 RYR3	2.18e-05	4	44	2	CID006444275
Drug	AC1O528X	RYR2 RYR3	5.45e-05	6	44	2	CID006475857
Drug	NSC114784	RYR2 RYR3	5.45e-05	6	44	2	CID000419425
Drug	MBED	RYR2 RYR3	5.45e-05	6	44	2	CID000129958
Drug	chloro-m-cresol	RYR2 RYR3	5.45e-05	6	44	2	CID000012008
Drug	Azumoleno	RYR2 RYR3	7.62e-05	7	44	2	CID000056259
Drug	[[(2R,3S,4R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [(2R,3S,4R,5R)-3,4,5-trihydroxyoxolan-2-yl]methyl hydrogen phosphate	RYR2 RYR3	7.62e-05	7	44	2	CID009547999
Drug	Br2BAPTA	RYR2 RYR3	7.62e-05	7	44	2	CID003081001
Drug	PCB 95	RYR2 RYR3	1.63e-04	10	44	2	CID000038012
Drug	R 478	RYR2 RYR3	1.99e-04	11	44	2	CID000084223
Drug	8-amino-cADPR	RYR2 RYR3	1.99e-04	11	44	2	CID003081323
Drug	PCB 66	RYR2 RYR3	1.99e-04	11	44	2	CID000036185
Disease	malignant hyperthermia (implicated_via_orthology)	RYR2 RYR3	4.34e-06	3	36	2	DOID:8545 (implicated_via_orthology)
Disease	congenital myopathy 1A (implicated_via_orthology)	RYR2 RYR3	4.34e-06	3	36	2	DOID:3529 (implicated_via_orthology)
Disease	Epileptic encephalopathy	RYR3 ALG13	6.16e-04	30	36	2	C0543888
Disease	monocyte count	PKD2L1 TGIF1 CDX2 GSG1L ERG ANK1 ZNF516	9.42e-04	1320	36	7	EFO_0005091
Disease	L2 Acute Lymphoblastic Leukemia	DUX4 ERG	1.71e-03	50	36	2	C0023453
Disease	Childhood Acute Lymphoblastic Leukemia	DUX4 ERG	1.85e-03	52	36	2	C0023452
Disease	Precursor Cell Lymphoblastic Leukemia Lymphoma	DUX4 ERG	2.53e-03	61	36	2	C1961102
Disease	disease progression measurement	POLR2A RYR3	2.53e-03	61	36	2	EFO_0008336

Protein segments in the cluster

Peptide	Gene	Start	Entry
GYYPSGGAWPEPGRA	BAG4	71	O95429
PGAYGMGGRYPWPSS	BAG4	246	O95429
DWAAAYGPGPAAPAA	CDX1	71	P47902
DSAQSPGPSWPAAYG	CDX2	56	Q99626
PPWHPVGTAYGGSSQ	ALG13	1096	Q9NP73
FLGWYTTGGPPDPSD	COPS6	121	Q7L5N1
PPASRPGAGYWGEYS	SMPD1	236	P17405
AAPGGGHPAPSWVAF	DUX4L4	166	P0CJ87
GASWGPPRGQYSAGA	ADRA2C	36	P18825
RGGSPHSPAWNGYTP	ANK1	591	P16157
GVAPAGFSYWPGPGP	FEV	186	Q99581
GFSYWPGPGPAATAA	FEV	191	Q99581
FAAPNPYWNSPTGGI	ERG	446	P11308
ASGNGPPGGALYSWE	GSG1L	76	Q6UXU4
PWSPSPGSAPWDYSG	GPR25	6	O00155
AAPGGGHPAPSWVAF	DUX4L6	166	P0CJ89
PYGTHGGWGASPYSP	RC3H1	916	Q5TC82
ISWGPSPTFGELGYG	RCC2	451	Q9P258
PGGGLSASGAPWYPI	HOXC12	196	P31275
AAPGGGHPAPSWVAF	DUX4	166	Q9UBX2
SPGGSPGDWGSLYSP	NEUROG3	161	Q9Y4Z2
PGAGDGPPRSFDWGY	NELFE	156	P18615
TGAPPGGQPDYSAAW	FUBP1	601	Q96AE4
AAPGGGHPAPSWVAF	DUX4L3	166	P0CJ86
PNTAWGSPSPEAAGY	MTSS2	641	Q765P7
PYGSGSGWSSSRGPY	HRNR	1496	Q86YZ3
PYGSGSGWSSSRGPY	HRNR	1966	Q86YZ3
PYGSGSGWSSSRGPY	HRNR	2436	Q86YZ3
AIPPPLSSVYAWGGG	NEK8	306	Q86SG6
GGYPDFPASPASWLD	LHX3	376	Q9UBR4
PAATGYPGAGDFLSW	EGR4	141	Q05215
HPPGAYWAGNPVFTA	NPAS4	176	Q8IUM7
FFGGWPKPASLSGGA	C1QTNF5	181	Q9BXJ0
GPFLPLTWPSCGFFG	C18orf15	76	Q96N68
AAPGGGHPAPSWVAF	DUX4L9	166	Q6RFH8
AAPGGGHPAPSWVAF	DUX4L7	166	P0CJ90
AAPGGGHPAPSWVAF	DUX4L5	166	P0CJ88
GWASTEGYSPYPGGG	RYR2	696	Q92736
GGGGSDSFPWPASHP	TGIF1	21	Q15583
SGGPCALWAPGPDGY	ZNF516	871	Q92618
LASGGPLWGPGYATT	SOX15	141	O60248
AGAAWAGPGGPFASP	VGLL2	276	Q8N8G2
SYGGPCGAAPVWGTP	RBMXL3	306	Q8N7X1
CGAAPVWGTPPSYGG	RBMXL3	311	Q8N7X1
SSSGYAPYPGGGEGW	RYR3	686	Q15413
GFSPGYSPAWSPTPG	POLR2A	1556	P24928
WGYGCGGPSTPGVYT	TMPRSS4	406	Q9NRS4
PAGIYPPGLWATVGS	TEX13C	266	A0A0J9YWL9
GSGAWDNPAYSGPPS	PKD2L1	16	Q9P0L9
AAPGGGHPAPSWVAF	DUX4L2	166	P0CJ85