Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionandrosterone dehydrogenase (B-specific) activity

AKR1C3 AKR1C4 AKR1C1 AKR1C2

6.41e-114584GO:0047042
GeneOntologyMolecularFunctionketoreductase activity

AKR1C3 AKR1C4 AKR1C1 AKR1C2

6.41e-114584GO:0045703
GeneOntologyMolecularFunctionchlordecone reductase activity

AKR1C3 AKR1C4 AKR1C1 AKR1C2

6.41e-114584GO:0047743
GeneOntologyMolecularFunctiontrans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity

AKR1C3 AKR1C4 AKR1C1 AKR1C2

3.20e-105584GO:0047115
GeneOntologyMolecularFunction15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity

AKR1C3 AKR1C4 AKR1C1 AKR1C2

3.20e-105584GO:0047020
GeneOntologyMolecularFunction17-beta-ketosteroid reductase (NADPH) activity

AKR1C3 AKR1C4 AKR1C1 AKR1C2

3.20e-105584GO:0072555
GeneOntologyMolecularFunction17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity

AKR1C3 AKR1C4 AKR1C1 AKR1C2

3.20e-105584GO:0047006
GeneOntologyMolecularFunctionDelta4-3-oxosteroid 5beta-reductase activity

AKR1C3 AKR1C4 AKR1C1 AKR1C2

3.20e-105584GO:0047787
GeneOntologyMolecularFunctionlithocholic acid binding

AKR1C3 AKR1C4 AKR1C1 AKR1C2

3.20e-105584GO:1902121
GeneOntologyMolecularFunctionketosteroid monooxygenase activity

AKR1C3 AKR1C4 AKR1C1 AKR1C2

3.20e-105584GO:0047086
GeneOntologyMolecularFunctiongeranylgeranyl reductase activity

AKR1C3 AKR1C4 AKR1C1 AKR1C2

9.57e-106584GO:0045550
GeneOntologyMolecularFunction17-beta-hydroxysteroid dehydrogenase (NADP+) activity

AKR1C3 AKR1C4 AKR1C1 AKR1C2

2.23e-097584GO:0072582
GeneOntologyMolecularFunction5alpha-androstane-3beta,17beta-diol dehydrogenase activity

AKR1C3 AKR1C4 AKR1C1 AKR1C2

4.45e-098584GO:0047024
GeneOntologyMolecularFunctionandrosterone dehydrogenase activity

AKR1C3 AKR1C4 AKR1C1 AKR1C2

4.45e-098584GO:0047023
GeneOntologyMolecularFunctionenone reductase activity

AKR1C3 AKR1C4 AKR1C1 AKR1C2

4.45e-098584GO:0035671
GeneOntologyMolecularFunctionandrostan-3-alpha,17-beta-diol dehydrogenase activity

AKR1C3 AKR1C4 AKR1C1 AKR1C2

7.99e-099584GO:0047044
GeneOntologyMolecularFunctionNADP+ binding

AKR1C3 AKR1C4 AKR1C1 AKR1C2

7.99e-099584GO:0070401
GeneOntologyMolecularFunctiontestosterone 17-beta-dehydrogenase (NADP+) activity

AKR1C3 AKR1C4 AKR1C1 AKR1C2

1.33e-0810584GO:0047045
GeneOntologyMolecularFunctionbile acid binding

AKR1C3 AKR1C4 AKR1C1 AKR1C2

1.33e-0810584GO:0032052
GeneOntologyMolecularFunctionretinal dehydrogenase activity

AKR1C3 AKR1C4 AKR1C1 AKR1C2

6.28e-0814584GO:0001758
GeneOntologyMolecularFunctionaldose reductase (NADPH) activity

AKR1C3 AKR1C4 AKR1C1 AKR1C2

6.28e-0814584GO:0004032
GeneOntologyMolecularFunctionestradiol 17-beta-dehydrogenase [NAD(P)+] activity

AKR1C3 AKR1C4 AKR1C1 AKR1C2

3.00e-0720584GO:0004303
GeneOntologyMolecularFunctionall-trans-retinol dehydrogenase (NAD+) activity

AKR1C3 AKR1C4 AKR1C1 AKR1C2

6.52e-0724584GO:0004745
GeneOntologyMolecularFunctionalcohol dehydrogenase (NAD+) activity

AKR1C3 AKR1C4 AKR1C1 AKR1C2

9.13e-0726584GO:0004022
GeneOntologyMolecularFunctionNADPH binding

AKR1C3 AKR1C4 AKR1C1 AKR1C2

9.13e-0726584GO:0070402
GeneOntologyMolecularFunctionalcohol dehydrogenase (NADP+) activity

AKR1C3 AKR1C4 AKR1C1 AKR1C2

1.07e-0627584GO:0008106
GeneOntologyMolecularFunctionalcohol dehydrogenase [NAD(P)+] activity

AKR1C3 AKR1C4 AKR1C1 AKR1C2

1.66e-0630584GO:0018455
GeneOntologyMolecularFunctionaldo-keto reductase (NADPH) activity

AKR1C3 AKR1C4 AKR1C1 AKR1C2

2.17e-0632584GO:0004033
GeneOntologyMolecularFunctionsteroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

AKR1C3 AKR1C4 AKR1C1 AKR1C2

2.46e-0633584GO:0033764
GeneOntologyMolecularFunctionoxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor

AKR1C3 AKR1C4 AKR1C1 AKR1C2

2.78e-0634584GO:0016628
GeneOntologyMolecularFunctiontestosterone dehydrogenase [NAD(P)+] activity

AKR1C3 AKR1C4 AKR1C1

3.77e-0611583GO:0030283
GeneOntologyMolecularFunctionsteroid dehydrogenase activity

AKR1C3 AKR1C4 AKR1C1 AKR1C2

4.89e-0639584GO:0016229
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen

AKR1C3 AKR1C4 AKR1C1 AKR1C2

5.42e-0640584GO:0016709
GeneOntologyMolecularFunctionoxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor

AKR1C3 AKR1C4 AKR1C1 AKR1C2

1.13e-0548584GO:0016620
GeneOntologyMolecularFunctionoxidoreductase activity, acting on the aldehyde or oxo group of donors

AKR1C3 AKR1C4 AKR1C1 AKR1C2

2.10e-0556584GO:0016903
GeneOntologyMolecularFunctionoxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor

AKR1C3 AKR1C4 AKR1C1 AKR1C2

2.77e-0560584GO:0016655
GeneOntologyMolecularFunctionoxidoreductase activity, acting on the CH-CH group of donors

AKR1C3 AKR1C4 AKR1C1 AKR1C2

3.15e-0562584GO:0016627
GeneOntologyMolecularFunctionNADP binding

AKR1C3 AKR1C4 AKR1C1 AKR1C2

3.15e-0562584GO:0050661
GeneOntologyMolecularFunctionindanol dehydrogenase activity

AKR1C1 AKR1C2

4.96e-054582GO:0047718
GeneOntologyMolecularFunctionoxidoreductase activity, acting on NAD(P)H

AKR1C3 AKR1C4 AKR1C1 AKR1C2

1.68e-0495584GO:0016651
GeneOntologyMolecularFunctionmonocarboxylic acid binding

AKR1C3 AKR1C4 AKR1C1 AKR1C2

2.65e-04107584GO:0033293
GeneOntologyMolecularFunctiontestosterone dehydrogenase (NAD+) activity

AKR1C3 AKR1C4

2.95e-049582GO:0047035
GeneOntologyMolecularFunctionmonooxygenase activity

AKR1C3 AKR1C4 AKR1C1 AKR1C2

3.48e-04115584GO:0004497
GeneOntologyMolecularFunctionoxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

AKR1C3 AKR1C4 AKR1C1 AKR1C2

5.08e-04127584GO:0016616
GeneOntologyMolecularFunctionsteroid binding

AKR1C3 AKR1C4 AKR1C1 AKR1C2

6.04e-04133584GO:0005496
GeneOntologyMolecularFunctionhistone H3K36 methyltransferase activity

NSD1 NSD3

6.34e-0413582GO:0046975
GeneOntologyMolecularFunctioncarboxylic acid binding

AKR1C3 AKR1C4 AKR1C1 AKR1C2 TNFRSF11B

6.44e-04239585GO:0031406
GeneOntologyMolecularFunctionoxidoreductase activity, acting on CH-OH group of donors

AKR1C3 AKR1C4 AKR1C1 AKR1C2

6.94e-04138584GO:0016614
GeneOntologyMolecularFunctionorganic acid binding

AKR1C3 AKR1C4 AKR1C1 AKR1C2 TNFRSF11B

8.47e-04254585GO:0043177
GeneOntologyMolecularFunctionintegrin binding

SFRP2 ADAM15 TSPAN8 SVEP1

1.67e-03175584GO:0005178
GeneOntologyMolecularFunctionextracellular matrix structural constituent

TFPI2 LTBP2 SSPOP MUC5AC

2.17e-03188584GO:0005201
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen

AKR1C3 AKR1C4 AKR1C1 AKR1C2

2.43e-03194584GO:0016705
GeneOntologyMolecularFunctionsulfur compound binding

SFRP1 CHST15 SLIT1 LTBP2 TNFRSF11B

2.44e-03323585GO:1901681
GeneOntologyMolecularFunctionWnt-protein binding

SFRP1 SFRP2

4.38e-0334582GO:0017147
GeneOntologyMolecularFunctionATP-dependent chromatin remodeler activity

CHD8 CHD6

5.17e-0337582GO:0140658
GeneOntologyMolecularFunctionlipid kinase activity

PIK3C2G DGKH

6.32e-0341582GO:0001727
GeneOntologyMolecularFunctionpeptidase regulator activity

SFRP2 CRIM1 TFPI2 SSPOP

6.60e-03257584GO:0061134
GeneOntologyMolecularFunctioncatalytic activity, acting on DNA

CHD8 CHD6 TERT DNMT1

7.06e-03262584GO:0140097
GeneOntologyMolecularFunctionhistone H3 methyltransferase activity

NSD1 NSD3

7.25e-0344582GO:0140938
GeneOntologyMolecularFunctionglycosaminoglycan binding

SFRP1 SLIT1 LTBP2 TNFRSF11B

7.63e-03268584GO:0005539
GeneOntologyMolecularFunctiontranscription coregulator binding

CHD6 MAP3K7 TERT

7.86e-03140583GO:0001221
GeneOntologyMolecularFunctionprotein serine/threonine/tyrosine kinase activity

DYRK1B MAP3K7

8.24e-0347582GO:0004712
GeneOntologyMolecularFunctionnuclear estrogen receptor binding

NSD1 DNMT1

1.04e-0253582GO:0030331
GeneOntologyMolecularFunctiontranscription coactivator binding

MAP3K7 TERT

1.08e-0254582GO:0001223
GeneOntologyMolecularFunctioncore promoter sequence-specific DNA binding

AGO1 REST

1.12e-0255582GO:0001046
GeneOntologyBiologicalProcessresponse to jasmonic acid

AKR1C3 AKR1C4 AKR1C1 AKR1C2

5.63e-114584GO:0009753
GeneOntologyBiologicalProcessprogesterone catabolic process

AKR1C3 AKR1C4 AKR1C1 AKR1C2

5.63e-114584GO:0006709
GeneOntologyBiologicalProcesscellular response to jasmonic acid stimulus

AKR1C3 AKR1C4 AKR1C1 AKR1C2

5.63e-114584GO:0071395
GeneOntologyBiologicalProcessC21-steroid hormone catabolic process

AKR1C3 AKR1C4 AKR1C1 AKR1C2

5.63e-114584GO:0008208
GeneOntologyBiologicalProcessfarnesol metabolic process

AKR1C3 AKR1C4 AKR1C1 AKR1C2

2.81e-105584GO:0016487
GeneOntologyBiologicalProcessfarnesol catabolic process

AKR1C3 AKR1C4 AKR1C1 AKR1C2

2.81e-105584GO:0016488
GeneOntologyBiologicalProcessnegative regulation of isoprenoid metabolic process

AKR1C3 AKR1C4 AKR1C1 AKR1C2

2.81e-105584GO:0045827
GeneOntologyBiologicalProcesssesquiterpenoid catabolic process

AKR1C3 AKR1C4 AKR1C1 AKR1C2

2.81e-105584GO:0016107
GeneOntologyBiologicalProcessolefinic compound catabolic process

AKR1C3 AKR1C4 AKR1C1 AKR1C2

2.81e-105584GO:0120256
GeneOntologyBiologicalProcessnegative regulation of retinoic acid biosynthetic process

AKR1C3 AKR1C4 AKR1C1 AKR1C2

2.81e-105584GO:1900053
GeneOntologyBiologicalProcessnegative regulation of hormone metabolic process

AKR1C3 AKR1C4 REST AKR1C1 AKR1C2

6.29e-1016585GO:0032351
GeneOntologyBiologicalProcesssesquiterpenoid metabolic process

AKR1C3 AKR1C4 AKR1C1 AKR1C2

8.41e-106584GO:0006714
GeneOntologyBiologicalProcesspolyprenol catabolic process

AKR1C3 AKR1C4 AKR1C1 AKR1C2

8.41e-106584GO:0016095
GeneOntologyBiologicalProcessresponse to prostaglandin D

AKR1C3 AKR1C4 AKR1C1 AKR1C2

1.96e-097584GO:0071798
GeneOntologyBiologicalProcesscellular response to prostaglandin D stimulus

AKR1C3 AKR1C4 AKR1C1 AKR1C2

1.96e-097584GO:0071799
GeneOntologyBiologicalProcessregulation of retinoic acid biosynthetic process

AKR1C3 AKR1C4 AKR1C1 AKR1C2

1.96e-097584GO:1900052
GeneOntologyBiologicalProcessparturition

AKR1C3 AKR1C4 RXFP1 AKR1C1 AKR1C2

3.74e-0922585GO:0007567
GeneOntologyBiologicalProcesstertiary alcohol metabolic process

AKR1C3 AKR1C4 REST AKR1C1 AKR1C2

3.74e-0922585GO:1902644
GeneOntologyBiologicalProcessdaunorubicin metabolic process

AKR1C3 AKR1C4 AKR1C1 AKR1C2

7.02e-099584GO:0044597
GeneOntologyBiologicalProcessregulation of ketone biosynthetic process

AKR1C3 AKR1C4 REST AKR1C1 AKR1C2

9.27e-0926585GO:0010566
GeneOntologyBiologicalProcessdoxorubicin metabolic process

AKR1C3 AKR1C4 AKR1C1 AKR1C2

1.17e-0810584GO:0044598
GeneOntologyBiologicalProcessregulation of isoprenoid metabolic process

AKR1C3 AKR1C4 AKR1C1 AKR1C2

1.17e-0810584GO:0019747
GeneOntologyBiologicalProcessnegative regulation of vitamin metabolic process

AKR1C3 AKR1C4 AKR1C1 AKR1C2

1.17e-0810584GO:0046137
GeneOntologyBiologicalProcesspolyketide metabolic process

AKR1C3 AKR1C4 AKR1C1 AKR1C2

1.17e-0810584GO:0030638
GeneOntologyBiologicalProcessaminoglycoside antibiotic metabolic process

AKR1C3 AKR1C4 AKR1C1 AKR1C2

1.17e-0810584GO:0030647
GeneOntologyBiologicalProcessregulation of testosterone biosynthetic process

AKR1C3 AKR1C4 AKR1C1 AKR1C2

1.83e-0811584GO:2000224
GeneOntologyBiologicalProcessterpenoid catabolic process

AKR1C3 AKR1C4 AKR1C1 AKR1C2

1.83e-0811584GO:0016115
GeneOntologyBiologicalProcessolefinic compound biosynthetic process

AKR1C3 AKR1C4 REST AKR1C1 AKR1C2

4.49e-0835585GO:0120255
GeneOntologyBiologicalProcessretinoic acid biosynthetic process

AKR1C3 AKR1C4 AKR1C1 AKR1C2

5.52e-0814584GO:0002138
GeneOntologyBiologicalProcessisoprenoid catabolic process

AKR1C3 AKR1C4 AKR1C1 AKR1C2

5.52e-0814584GO:0008300
GeneOntologyBiologicalProcessditerpenoid biosynthetic process

AKR1C3 AKR1C4 AKR1C1 AKR1C2

7.51e-0815584GO:0016102
GeneOntologyBiologicalProcesstestosterone biosynthetic process

AKR1C3 AKR1C4 AKR1C1 AKR1C2

9.99e-0816584GO:0061370
GeneOntologyBiologicalProcessC21-steroid hormone metabolic process

AKR1C3 AKR1C4 REST AKR1C1 AKR1C2

1.65e-0745585GO:0008207
GeneOntologyBiologicalProcessregulation of vitamin metabolic process

AKR1C3 AKR1C4 AKR1C1 AKR1C2

1.67e-0718584GO:0030656
GeneOntologyBiologicalProcesshormone catabolic process

AKR1C3 AKR1C4 AKR1C1 AKR1C2

3.25e-0721584GO:0042447
GeneOntologyBiologicalProcessterpenoid biosynthetic process

AKR1C3 AKR1C4 AKR1C1 AKR1C2

3.25e-0721584GO:0016114
GeneOntologyBiologicalProcessregulation of retinoic acid receptor signaling pathway

AKR1C3 AKR1C4 AKR1C1 AKR1C2

3.25e-0721584GO:0048385
GeneOntologyBiologicalProcessretinal metabolic process

AKR1C3 AKR1C4 AKR1C1 AKR1C2

3.25e-0721584GO:0042574
GeneOntologyBiologicalProcessketone catabolic process

AKR1C3 AKR1C4 AKR1C1 AKR1C2

3.25e-0721584GO:0042182
GeneOntologyBiologicalProcesscellular response to transforming growth factor beta stimulus

MTMR4 AKR1C3 LTBP2 AKR1C4 MAP3K7 AKR1C1 AKR1C2 ZEB2 DNMT1

3.83e-07336589GO:0071560
GeneOntologyBiologicalProcessglycoside metabolic process

AKR1C3 AKR1C4 AKR1C1 AKR1C2

3.96e-0722584GO:0016137
GeneOntologyBiologicalProcessprogesterone metabolic process

AKR1C3 AKR1C4 AKR1C1 AKR1C2

3.96e-0722584GO:0042448
GeneOntologyBiologicalProcessresponse to estrogen

SFRP1 AKR1C3 AKR1C4 AKR1C1 AKR1C2 TNFRSF11B

4.39e-07103586GO:0043627
GeneOntologyBiologicalProcessresponse to transforming growth factor beta

MTMR4 AKR1C3 LTBP2 AKR1C4 MAP3K7 AKR1C1 AKR1C2 ZEB2 DNMT1

4.55e-07343589GO:0071559
GeneOntologyBiologicalProcesscellular response to prostaglandin stimulus

AKR1C3 AKR1C4 AKR1C1 AKR1C2

4.79e-0723584GO:0071379
GeneOntologyBiologicalProcessprimary alcohol catabolic process

AKR1C3 AKR1C4 AKR1C1 AKR1C2

4.79e-0723584GO:0034310
GeneOntologyBiologicalProcessketone biosynthetic process

AKR1C3 AKR1C4 REST AKR1C1 AKR1C2

5.52e-0757585GO:0042181
GeneOntologyBiologicalProcessregulation of hormone metabolic process

AKR1C3 AKR1C4 REST AKR1C1 AKR1C2

6.03e-0758585GO:0032350
GeneOntologyBiologicalProcessnegative regulation of mRNA splicing, via spliceosome

AKR1C3 AKR1C4 AKR1C1 AKR1C2

1.10e-0628584GO:0048025
GeneOntologyBiologicalProcesssecondary metabolic process

AKR1C3 AKR1C4 AKR1C1 AKR1C2 ZEB2

1.25e-0667585GO:0019748
GeneOntologyBiologicalProcesspolyprenol metabolic process

AKR1C3 AKR1C4 AKR1C1 AKR1C2

1.27e-0629584GO:0016093
GeneOntologyBiologicalProcessnegative regulation of mRNA processing

AKR1C3 AKR1C4 AKR1C1 AKR1C2

1.27e-0629584GO:0050686
GeneOntologyBiologicalProcesspositive regulation of endothelial cell apoptotic process

AKR1C3 AKR1C4 AKR1C1 AKR1C2

1.91e-0632584GO:2000353
GeneOntologyBiologicalProcessregulation of endothelial cell apoptotic process

AKR1C3 AKR1C4 TERT AKR1C1 AKR1C2

2.05e-0674585GO:2000351
GeneOntologyBiologicalProcessnegative regulation of RNA splicing

AKR1C3 AKR1C4 AKR1C1 AKR1C2

2.17e-0633584GO:0033119
GeneOntologyBiologicalProcesssteroid catabolic process

AKR1C3 AKR1C4 AKR1C1 AKR1C2

2.45e-0634584GO:0006706
GeneOntologyBiologicalProcessendothelial cell apoptotic process

AKR1C3 AKR1C4 TERT AKR1C1 AKR1C2

2.83e-0679585GO:0072577
GeneOntologyBiologicalProcessresponse to prostaglandin

AKR1C3 AKR1C4 AKR1C1 AKR1C2

3.10e-0636584GO:0034694
GeneOntologyBiologicalProcessisoprenoid biosynthetic process

AKR1C3 AKR1C4 AKR1C1 AKR1C2

3.10e-0636584GO:0008299
GeneOntologyBiologicalProcesscellular response to corticosteroid stimulus

AKR1C3 AKR1C4 REST AKR1C1 AKR1C2

3.21e-0681585GO:0071384
GeneOntologyBiologicalProcesscellular response to growth factor stimulus

MTMR4 SFRP1 SFRP2 CRIM1 AKR1C3 LTBP2 AKR1C4 MAP3K7 AKR1C1 AKR1C2 ZEB2 DNMT1

3.45e-068505812GO:0071363
GeneOntologyBiologicalProcessretinoic acid receptor signaling pathway

AKR1C3 AKR1C4 AKR1C1 AKR1C2

3.87e-0638584GO:0048384
GeneOntologyBiologicalProcessretinoic acid metabolic process

AKR1C3 AKR1C4 AKR1C1 AKR1C2

4.77e-0640584GO:0042573
GeneOntologyBiologicalProcessresponse to growth factor

MTMR4 SFRP1 SFRP2 CRIM1 AKR1C3 LTBP2 AKR1C4 MAP3K7 AKR1C1 AKR1C2 ZEB2 DNMT1

5.09e-068835812GO:0070848
GeneOntologyBiologicalProcessnegative regulation of lipid biosynthetic process

AKR1C3 AKR1C4 REST AKR1C1 AKR1C2

5.70e-0691585GO:0051055
GeneOntologyBiologicalProcesscellular response to fatty acid

AKR1C3 AKR1C4 AKR1C1 AKR1C2

5.82e-0642584GO:0071398
GeneOntologyBiologicalProcessaldehyde metabolic process

AKR1C3 AKR1C4 REST AKR1C1 AKR1C2

7.04e-0695585GO:0006081
GeneOntologyBiologicalProcessalcohol catabolic process

AKR1C3 AKR1C4 AKR1C1 AKR1C2

9.17e-0647584GO:0046164
GeneOntologyBiologicalProcessprimary alcohol metabolic process

AKR1C3 AKR1C4 REST AKR1C1 AKR1C2

1.20e-05106585GO:0034308
GeneOntologyBiologicalProcessregulation of steroid biosynthetic process

AKR1C3 AKR1C4 REST AKR1C1 AKR1C2

1.20e-05106585GO:0050810
GeneOntologyBiologicalProcessresponse to xenobiotic stimulus

SFRP1 SFRP2 AKR1C3 AKR1C4 REST AKR1C1 AKR1C2 TNFRSF11B DNMT1

1.47e-05525589GO:0009410
GeneOntologyBiologicalProcessprostaglandin metabolic process

AKR1C3 AKR1C4 AKR1C1 AKR1C2

1.85e-0556584GO:0006693
GeneOntologyBiologicalProcessprostanoid metabolic process

AKR1C3 AKR1C4 AKR1C1 AKR1C2

1.99e-0557584GO:0006692
GeneOntologyBiologicalProcessregulation of midbrain dopaminergic neuron differentiation

SFRP1 SFRP2

2.33e-053582GO:1904956
GeneOntologyBiologicalProcesspositive regulation of epithelial cell apoptotic process

AKR1C3 AKR1C4 AKR1C1 AKR1C2

2.44e-0560584GO:1904037
GeneOntologyBiologicalProcessregulation of mRNA splicing, via spliceosome

AKR1C3 AKR1C4 REST AKR1C1 AKR1C2

3.11e-05129585GO:0048024
GeneOntologyBiologicalProcesscellular response to ketone

ADAM15 AKR1C3 AKR1C4 AKR1C1 AKR1C2

3.23e-05130585GO:1901655
GeneOntologyBiologicalProcesscellular response to alcohol

ADAM15 AKR1C3 AKR1C4 AKR1C1 AKR1C2

3.23e-05130585GO:0097306
GeneOntologyBiologicalProcessregulation of JUN kinase activity

SFRP1 SFRP2 MAP3K7 ZEB2

3.78e-0567584GO:0043506
GeneOntologyBiologicalProcessregulation of steroid metabolic process

AKR1C3 AKR1C4 REST AKR1C1 AKR1C2

3.87e-05135585GO:0019218
GeneOntologyBiologicalProcessresponse to fatty acid

AKR1C3 AKR1C4 AKR1C1 AKR1C2

4.25e-0569584GO:0070542
GeneOntologyBiologicalProcessnegative regulation of Wnt signaling pathway, planar cell polarity pathway

SFRP1 SFRP2

4.65e-054582GO:0141113
GeneOntologyBiologicalProcessWnt signaling pathway involved in somitogenesis

SFRP1 SFRP2

4.65e-054582GO:0090244
GeneOntologyBiologicalProcessorganic hydroxy compound catabolic process

AKR1C3 AKR1C4 AKR1C1 AKR1C2

5.30e-0573584GO:1901616
GeneOntologyBiologicalProcessnegative regulation of lipid metabolic process

AKR1C3 AKR1C4 REST AKR1C1 AKR1C2

5.44e-05145585GO:0045833
GeneOntologyBiologicalProcesscellular response to steroid hormone stimulus

SFRP1 AKR1C3 AKR1C4 REST AKR1C1 AKR1C2

5.56e-05239586GO:0071383
GeneOntologyBiologicalProcessnegative regulation of small molecule metabolic process

AKR1C3 AKR1C4 REST AKR1C1 AKR1C2

6.19e-05149585GO:0062014
GeneOntologyBiologicalProcesshormone-mediated signaling pathway

SFRP1 AKR1C3 AKR1C4 RXFP1 AKR1C1 AKR1C2

6.24e-05244586GO:0009755
GeneOntologyBiologicalProcessregulation of epithelial cell apoptotic process

AKR1C3 AKR1C4 TERT AKR1C1 AKR1C2

6.81e-05152585GO:1904035
GeneOntologyBiologicalProcessnegative regulation of BMP signaling pathway

MTMR4 SFRP1 SFRP2 CRIM1

7.59e-0580584GO:0030514
GeneOntologyBiologicalProcessregulation of mRNA processing

AKR1C3 AKR1C4 REST AKR1C1 AKR1C2

8.18e-05158585GO:0050684
GeneOntologyBiologicalProcesspositive regulation of Wnt signaling pathway

USP34 SFRP1 SFRP2 TERT ZEB2

8.18e-05158585GO:0030177
GeneOntologyBiologicalProcesscellular response to calcium ion

AKR1C3 AKR1C4 AKR1C1 AKR1C2

1.10e-0488584GO:0071277
GeneOntologyBiologicalProcesspositive regulation of reactive oxygen species metabolic process

AKR1C3 AKR1C4 AKR1C1 AKR1C2

1.15e-0489584GO:2000379
GeneOntologyBiologicalProcessretinoid metabolic process

AKR1C3 AKR1C4 AKR1C1 AKR1C2

1.15e-0489584GO:0001523
GeneOntologyBiologicalProcessorganic hydroxy compound biosynthetic process

AKR1C3 AKR1C4 REST AKR1C1 AKR1C2 ZEB2

1.25e-04277586GO:1901617
GeneOntologyBiologicalProcessditerpenoid metabolic process

AKR1C3 AKR1C4 AKR1C1 AKR1C2

1.42e-0494584GO:0016101
GeneOntologyBiologicalProcessnegative regulation of cell differentiation

SFRP1 SFRP2 CRIM1 SLIT1 REST ZHX2 TERT USH2A TNFRSF11B DNMT1

1.47e-048755810GO:0045596
GeneOntologyBiologicalProcessolefinic compound metabolic process

AKR1C3 AKR1C4 REST AKR1C1 AKR1C2

1.51e-04180585GO:0120254
GeneOntologyBiologicalProcessglycosyl compound metabolic process

AKR1C3 AKR1C4 AKR1C1 AKR1C2

1.54e-0496584GO:1901657
GeneOntologyCellularComponentradial spoke stalk

CFAP251 CFAP61

2.19e-053572GO:0001536
GeneOntologyCellularComponentextracellular matrix

SFRP1 SFRP2 TFPI2 LTBP2 USH2A SSPOP MUC5AC SVEP1 TNFRSF11B

6.54e-05656579GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

SFRP1 SFRP2 TFPI2 LTBP2 USH2A SSPOP MUC5AC SVEP1 TNFRSF11B

6.69e-05658579GO:0030312
GeneOntologyCellularComponentradial spoke

CFAP251 CFAP61

7.50e-0415572GO:0001534
MousePhenodecreased oligodendrocyte number

AKR1C3 AKR1C4 TERT AKR1C1 AKR1C2

1.94e-0825485MP:0009808
MousePhenoparturition failure

AKR1C3 AKR1C4 AKR1C1 AKR1C2

2.53e-0810484MP:0012010
MousePhenohypermyelination

AKR1C3 AKR1C4 AKR1C1 AKR1C2

3.97e-0811484MP:0010050
MousePhenoabnormal parturition

AKR1C3 AKR1C4 RXFP1 AKR1C1 AKR1C2

8.51e-0833485MP:0002907
MousePhenoincreased oligodendrocyte number

AKR1C3 AKR1C4 AKR1C1 AKR1C2

8.55e-0813484MP:0010160
MousePhenolong gestation period

AKR1C3 AKR1C4 AKR1C1 AKR1C2

1.62e-0715484MP:0002293
MousePhenoincreased circulating progesterone level

AKR1C3 AKR1C4 AKR1C1 AKR1C2

1.62e-0715484MP:0005186
MousePhenolong stride length

AKR1C3 AKR1C4 AKR1C1 AKR1C2

1.62e-0715484MP:0010540
MousePhenoabnormal gestational length

AKR1C3 AKR1C4 AKR1C1 AKR1C2

3.61e-0718484MP:0002292
MousePhenodysmyelination

AKR1C3 AKR1C4 AKR1C1 AKR1C2

5.69e-0720484MP:0013438
MousePhenoabnormal oligodendrocyte morphology

AKR1C3 AKR1C4 TERT AKR1C1 AKR1C2

8.04e-0751485MP:0000953
MousePhenoprolonged diestrus

AKR1C3 AKR1C4 AKR1C1 AKR1C2

3.14e-0630484MP:0009011
MousePhenoabnormal diestrus

AKR1C3 AKR1C4 AKR1C1 AKR1C2

5.92e-0635484MP:0009010
MousePhenoenhanced coordination

AKR1C3 AKR1C4 AKR1C1 AKR1C2

8.29e-0638484MP:0003858
MousePhenoprolonged estrous cycle

AKR1C3 AKR1C4 AKR1C1 AKR1C2

9.21e-0639484MP:0009006
MousePhenodecreased vocalization

AKR1C3 AKR1C4 AKR1C1 AKR1C2

1.80e-0546484MP:0020351
MousePhenoabnormal circulating progesterone level

AKR1C3 AKR1C4 AKR1C1 AKR1C2

2.51e-0550484MP:0005184
MousePhenoincreased stereotypic behavior

AKR1C3 AKR1C4 AKR1C1 AKR1C2

3.17e-0553484MP:0001409
MousePhenoabnormal progesterone level

AKR1C3 AKR1C4 AKR1C1 AKR1C2

3.41e-0554484MP:0011384
MousePhenoincreased erythrocyte cell number

AKR1C3 AKR1C4 AKR1C1 AKR1C2 SVEP1

6.15e-05123485MP:0003131
MousePhenolens dislocation

CRIM1 LTBP2

1.72e-046482MP:0031428
MousePhenoabnormal stride length

AKR1C3 AKR1C4 AKR1C1 AKR1C2

1.76e-0482484MP:0012690
MousePhenoabnormal myelination

AKR1C3 AKR1C4 TERT AKR1C1 AKR1C2

2.52e-04166485MP:0000920
MousePhenoincreased interleukin level

TFPI2 AKR1C3 AKR1C4 AKR1C1 AKR1C2

3.13e-04174485MP:0014437
MousePhenoabnormal lens topology

CRIM1 LTBP2

7.45e-0412482MP:0020486
MousePhenoabnormal estrous cycle

AKR1C3 AKR1C4 AKR1C1 AKR1C2

7.51e-04120484MP:0001927
MousePhenoabnormal ovulation cycle

AKR1C3 AKR1C4 AKR1C1 AKR1C2

9.01e-04126484MP:0009344
MousePhenoincreased myeloid cell number

ZNF689 AKR1C3 AKR1C4 AKR1C1 AKR1C2 SVEP1

1.07e-03343486MP:0013663
MousePhenodecreased miniature inhibitory postsynaptic current amplitude

CHD8 TRIM3

1.18e-0315482MP:0014385
MousePhenoabnormal pregnancy

AKR1C3 AKR1C4 RXFP1 AKR1C1 AKR1C2

1.22e-03235485MP:0009661
MousePhenoabnormal vocalization

AKR1C3 CHD8 AKR1C4 AKR1C1 AKR1C2

1.27e-03237485MP:0001529
DomainALDOKETO_REDUCTASE_1

AKR1C3 AKR1C4 AKR1C1 AKR1C2

1.50e-0810564PS00798
DomainAldo/ket_reductase_CS

AKR1C3 AKR1C4 AKR1C1 AKR1C2

1.50e-0810564IPR018170
DomainAldo/keto_reductase

AKR1C3 AKR1C4 AKR1C1 AKR1C2

1.50e-0810564IPR020471
DomainALDOKETO_REDUCTASE_2

AKR1C3 AKR1C4 AKR1C1 AKR1C2

1.50e-0810564PS00062
DomainALDOKETO_REDUCTASE_3

AKR1C3 AKR1C4 AKR1C1 AKR1C2

1.50e-0810564PS00063
Domain-

AKR1C3 AKR1C4 AKR1C1 AKR1C2

1.28e-07165643.20.20.100
DomainNADP_OxRdtase_dom

AKR1C3 AKR1C4 AKR1C1 AKR1C2

1.68e-0717564IPR023210
DomainAldo_ket_red

AKR1C3 AKR1C4 AKR1C1 AKR1C2

1.68e-0717564PF00248
DomainAldo/ket_red/Kv-b

AKR1C3 AKR1C4 AKR1C1 AKR1C2

1.68e-0717564IPR001395
DomainCTCK_1

SLIT1 SSPOP MUC5AC

2.02e-0518563PS01185
DomainVWC_out

CRIM1 SSPOP MUC5AC

2.39e-0519563SM00215
DomainCys_knot_C

SLIT1 SSPOP MUC5AC

5.60e-0525563IPR006207
DomainCTCK_2

SLIT1 SSPOP MUC5AC

5.60e-0525563PS01225
DomainAWS

NSD1 NSD3

8.78e-055562SM00570
DomainAWS

NSD1 NSD3

8.78e-055562PS51215
DomainAWS_dom

NSD1 NSD3

8.78e-055562IPR006560
DomainEGF_1

ADAM15 SLIT1 LTBP2 USH2A SSPOP SVEP1

1.12e-04255566PS00022
DomainBRK

CHD8 CHD6

1.31e-046562SM00592
DomainBRK_domain

CHD8 CHD6

1.31e-046562IPR006576
DomainBRK

CHD8 CHD6

1.31e-046562PF07533
DomainVWFC_1

CRIM1 SSPOP MUC5AC

1.70e-0436563PS01208
DomainHirudin/antistatin

CRIM1 MUC5AC

1.84e-047562IPR011061
DomainVWC

CRIM1 SSPOP MUC5AC

2.00e-0438563SM00214
DomainVWFC_2

CRIM1 SSPOP MUC5AC

2.00e-0438563PS50184
DomainVWF_dom

CRIM1 SSPOP MUC5AC

2.70e-0442563IPR001007
DomainNHL_repeat_subgr

TRIM2 TRIM3

3.14e-049562IPR013017
DomainIG_FLMN

TRIM2 TRIM3

3.91e-0410562SM00557
DomainNHL

TRIM2 TRIM3

3.91e-0410562PF01436
DomainNHL_repeat

TRIM2 TRIM3

3.91e-0410562IPR001258
DomainFilamin

TRIM2 TRIM3

4.77e-0411562PF00630
DomainFILAMIN_REPEAT

TRIM2 TRIM3

4.77e-0411562PS50194
DomainFilamin/ABP280_rpt

TRIM2 TRIM3

4.77e-0411562IPR001298
DomainFilamin/ABP280_repeat-like

TRIM2 TRIM3

4.77e-0411562IPR017868
DomainTIL

SSPOP MUC5AC

5.72e-0412562PF01826
DomainC8

SSPOP MUC5AC

5.72e-0412562PF08742
DomainUnchr_dom_Cys-rich

SSPOP MUC5AC

6.74e-0413562IPR014853
DomainC8

SSPOP MUC5AC

6.74e-0413562SM00832
DomainNHL

TRIM2 TRIM3

6.74e-0413562PS51125
DomainEGF_3

ADAM15 SLIT1 LTBP2 SSPOP SVEP1

6.85e-04235565PS50026
DomainEGF_extracell

ADAM15 LTBP2 SVEP1

7.74e-0460563IPR013111
DomainEGF_2

ADAM15 LTBP2 SVEP1

7.74e-0460563PF07974
DomainTIL_dom

SSPOP MUC5AC

7.85e-0414562IPR002919
DomainBbox_C

TRIM2 TRIM3

9.04e-0415562IPR003649
DomainBBC

TRIM2 TRIM3

9.04e-0415562SM00502
DomainPost-SET_dom

NSD1 NSD3

1.03e-0316562IPR003616
DomainVWD

SSPOP MUC5AC

1.03e-0316562SM00216
DomainPostSET

NSD1 NSD3

1.03e-0316562SM00508
DomainVWF_type-D

SSPOP MUC5AC

1.03e-0316562IPR001846
DomainVWFD

SSPOP MUC5AC

1.03e-0316562PS51233
DomainPOST_SET

NSD1 NSD3

1.03e-0316562PS50868
DomainVWD

SSPOP MUC5AC

1.03e-0316562PF00094
DomainFrizzled/SFRP

SFRP1 SFRP2

1.03e-0316562IPR015526
DomainC345C

SFRP1 SFRP2

1.17e-0317562SM00643
DomainEGF_2

ADAM15 SLIT1 LTBP2 SSPOP SVEP1

1.17e-03265565PS01186
DomainGrowth_fac_rcpt_

CRIM1 SLIT1 LTBP2 SVEP1

1.23e-03156564IPR009030
DomainNTR

SFRP1 SFRP2

1.46e-0319562PF01759
DomainNetrin_module_non-TIMP

SFRP1 SFRP2

1.46e-0319562IPR018933
DomainFRI

SFRP1 SFRP2

1.62e-0320562SM00063
DomainPWWP

NSD1 NSD3

1.62e-0320562SM00293
DomainLRR_8

AMIGO3 SLIT1 PIDD1 RXFP1

1.72e-03171564PF13855
Domain-

SFRP1 SFRP2

1.79e-03215621.10.2000.10
DomainLeu-rich_rpt_typical-subtyp

AMIGO3 SLIT1 PIDD1 RXFP1

1.95e-03177564IPR003591
DomainLRR_TYP

AMIGO3 SLIT1 PIDD1 RXFP1

1.95e-03177564SM00369
DomainCT

SLIT1 MUC5AC

1.96e-0322562SM00041
DomainQuino_amine_DH_bsu

TRIM2 TRIM3

1.96e-0322562IPR011044
DomainPWWP

NSD1 NSD3

2.15e-0323562PF00855
DomainPWWP_dom

NSD1 NSD3

2.15e-0323562IPR000313
DomainNTR

SFRP1 SFRP2

2.15e-0323562PS50189
DomainNetrin_domain

SFRP1 SFRP2

2.15e-0323562IPR001134
DomainRING

TRIM2 NSD1 UBOX5 TRIM3 NSD3

2.17e-03305565SM00184
Domain-

MTMR4 TRIM2 NSD1 UBOX5 TRIM3 NSD3

2.19e-034495663.30.40.10
DomainPWWP

NSD1 NSD3

2.34e-0324562PS50812
DomainFrizzled_dom

SFRP1 SFRP2

2.34e-0324562IPR020067
DomainChromo_domain

CHD8 CHD6

2.34e-0324562IPR023780
DomainFZ

SFRP1 SFRP2

2.34e-0324562PS50038
DomainFz

SFRP1 SFRP2

2.34e-0324562PF01392
DomainZnf_RING/FYVE/PHD

MTMR4 TRIM2 NSD1 UBOX5 TRIM3 NSD3

2.45e-03459566IPR013083
DomainEphrin_rec_like

SVEP1 TNFRSF11B

2.53e-0325562SM01411
DomainTyr-kin_ephrin_A/B_rcpt-like

SVEP1 TNFRSF11B

2.53e-0325562IPR011641
DomainTIMP-like_OB-fold

SFRP1 SFRP2

2.74e-0326562IPR008993
DomainChromo

CHD8 CHD6

2.74e-0326562PF00385
DomainZnf_RING

TRIM2 NSD1 UBOX5 TRIM3 NSD3

2.90e-03326565IPR001841
Domain-

SLIT1 USH2A SVEP1

2.91e-03955632.60.120.200
DomainDEATH

PIDD1 TNFRSF11B

2.95e-0327562SM00005
PathwayWP_BENZOAPYRENE_METABOLISM

AKR1C3 AKR1C4 AKR1C1 AKR1C2

1.03e-089444M39344
PathwayKEGG_MEDICUS_ENV_FACTOR_METALS_TO_KEAP1_NRF2_SIGNALIG_PATHWAY

AKR1C3 AKR1C4 AKR1C1 AKR1C2

1.03e-089444M47817
PathwayKEGG_MEDICUS_ENV_FACTOR_BENZO_A_PYRENRE_TO_CYP_MEDIATED_METABOLISM

AKR1C3 AKR1C4 AKR1C1 AKR1C2

2.68e-0811444M47812
PathwayREACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL

AKR1C3 AKR1C4 AKR1C1 AKR1C2

5.78e-0813444M17842
PathwayREACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL

AKR1C3 AKR1C4 AKR1C1 AKR1C2

5.78e-0813444MM14747
PathwayWP_GLUCOCORTICOID_BIOSYNTHESIS

AKR1C3 AKR1C4 AKR1C1 AKR1C2

8.08e-0814444M46449
PathwayREACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_27_HYDROXYCHOLESTEROL

AKR1C3 AKR1C4 AKR1C1 AKR1C2

8.08e-0814444M27074
PathwayWP_MINERALOCORTICOID_BIOSYNTHESIS

AKR1C3 AKR1C4 AKR1C1 AKR1C2

8.08e-0814444M46453
PathwayREACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_27_HYDROXYCHOLESTEROL

AKR1C3 AKR1C4 AKR1C1 AKR1C2

8.08e-0814444MM14748
PathwayREACTOME_SYNTHESIS_OF_PROSTAGLANDINS_PG_AND_THROMBOXANES_TX

AKR1C3 AKR1C4 AKR1C1 AKR1C2

1.10e-0715444MM14870
PathwayREACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_7ALPHA_HYDROXYCHOLESTEROL

AKR1C3 AKR1C4 AKR1C1 AKR1C2

7.00e-0723444M1926
PathwayREACTOME_PREDNISONE_ADME

AKR1C3 AKR1C4 AKR1C1 AKR1C2

7.00e-0723444MM16639
PathwayREACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_7ALPHA_HYDROXYCHOLESTEROL

AKR1C3 AKR1C4 AKR1C1 AKR1C2

7.00e-0723444MM14741
PathwayREACTOME_RA_BIOSYNTHESIS_PATHWAY

AKR1C3 AKR1C4 AKR1C1 AKR1C2

1.60e-0628444MM15188
PathwayREACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS

AKR1C3 AKR1C4 AKR1C1 AKR1C2

3.16e-0633444M5967
PathwayREACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS

AKR1C3 AKR1C4 AKR1C1 AKR1C2

3.16e-0633444MM14737
PathwayREACTOME_BILE_ACID_AND_BILE_SALT_METABOLISM

AKR1C3 AKR1C4 AKR1C1 AKR1C2

1.02e-0544444M499
PathwayREACTOME_METABOLISM_OF_FAT_SOLUBLE_VITAMINS

AKR1C3 AKR1C4 AKR1C1 AKR1C2

1.12e-0545444MM15344
PathwayREACTOME_BILE_ACID_AND_BILE_SALT_METABOLISM

AKR1C3 AKR1C4 AKR1C1 AKR1C2

1.12e-0545444MM14751
PathwayREACTOME_SIGNALING_BY_RETINOIC_ACID

AKR1C3 AKR1C4 AKR1C1 AKR1C2

1.58e-0549444MM15186
PathwayWP_MAMMARY_GLAND_DEVELOPMENT_EMBRYONIC_DEVELOPMENT_STAGE_1_OF_4

SFRP1 TERT ZEB2

2.24e-0518443M39327
PathwayKEGG_STEROID_HORMONE_BIOSYNTHESIS

AKR1C3 AKR1C4 AKR1C1 AKR1C2

2.51e-0555444M14933
PathwayREACTOME_ARACHIDONIC_ACID_METABOLISM

AKR1C3 AKR1C4 AKR1C1 AKR1C2

3.78e-0561444MM14861
PathwayKEGG_METABOLISM_OF_XENOBIOTICS_BY_CYTOCHROME_P450

AKR1C3 AKR1C4 AKR1C1 AKR1C2

6.51e-0570444M16794
PathwayREACTOME_SIGNALING_BY_WNT

USP34 SFRP1 SFRP2 AGO1 CHD8 MAP3K7 TERT

6.58e-05330447M7847
PathwayREACTOME_VISUAL_PHOTOTRANSDUCTION

AKR1C3 AKR1C4 AKR1C1 AKR1C2

1.89e-0492444MM14881
PathwayWP_LNCRNA_IN_CANONICAL_WNT_SIGNALING_AND_COLORECTAL_CANCER

SFRP1 SFRP2 CHD8 MAP3K7

2.41e-0498444M39731
PathwayWP_PROSTAGLANDIN_SYNTHESIS_AND_REGULATION

AKR1C3 AKR1C1 AKR1C2

3.67e-0445443M39355
PathwayWP_WNT_SIGNALING_WP428

SFRP1 SFRP2 CHD8 MAP3K7

4.15e-04113444M39669
PathwayREACTOME_METABOLISM_OF_FAT_SOLUBLE_VITAMINS

AKR1C3 AKR1C4 AKR1C1

4.45e-0448443M27642
PathwayREACTOME_DRUG_ADME

AKR1C3 AKR1C4 AKR1C1 AKR1C2

5.05e-04119444MM15692
PathwayWP_ALTERNATIVE_PATHWAY_OF_FETAL_ANDROGEN_SYNTHESIS

AKR1C4 AKR1C2

5.14e-0411442M39749
PathwayREACTOME_METABOLISM_OF_STEROIDS

AKR1C3 AKR1C4 AKR1C1 AKR1C2

6.26e-04126444MM15553
PathwayREACTOME_REGULATION_OF_NPAS4_GENE_EXPRESSION

AGO1 REST

7.27e-0413442M46434
PathwayREACTOME_TCF_DEPENDENT_SIGNALING_IN_RESPONSE_TO_WNT

USP34 SFRP1 SFRP2 CHD8 TERT

7.59e-04233445M27099
PathwayREACTOME_NEGATIVE_REGULATION_OF_TCF_DEPENDENT_SIGNALING_BY_WNT_LIGAND_ANTAGONISTS

SFRP1 SFRP2

9.74e-0415442M27273
PathwayWP_FERROPTOSIS

AKR1C3 AKR1C1 AKR1C2

1.03e-0364443M39768
PathwayKEGG_WNT_SIGNALING_PATHWAY

SFRP1 SFRP2 CHD8 MAP3K7

1.23e-03151444M19428
PathwayREACTOME_METABOLISM_OF_STEROIDS

AKR1C3 AKR1C4 AKR1C1 AKR1C2

1.32e-03154444M27832
PathwayREACTOME_FATTY_ACID_METABOLISM

AKR1C3 AKR1C4 AKR1C1 AKR1C2

1.90e-03170444MM15573
PathwayPID_BETA_CATENIN_NUC_PATHWAY

CHD8 TERT SSPOP

1.97e-0380443M223
PathwayKEGG_GLYCOSAMINOGLYCAN_BIOSYNTHESIS_CHONDROITIN_SULFATE

CHST15 B3GAT3

2.11e-0322442M19166
PathwayWP_METAPATHWAY_BIOTRANSFORMATION_PHASE_I_AND_II

AKR1C3 AKR1C4 AKR1C1 AKR1C2

2.49e-03183444M39588
PathwayWP_NCRNAS_INVOLVED_IN_WNT_SIGNALING_IN_HEPATOCELLULAR_CARCINOMA

SFRP1 SFRP2 CHD8

2.67e-0389443M39563
PathwayREACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS

AKR1C3 AKR1C4 AKR1C1 AKR1C2

2.80e-03189444MM14772
PathwayREACTOME_SENSORY_PERCEPTION

AKR1C3 AKR1C4 AKR1C1 AKR1C2

2.85e-03190444MM15687
PathwayREACTOME_SIGNALING_BY_NUCLEAR_RECEPTORS

AKR1C3 AKR1C4 AKR1C1 AKR1C2

2.90e-03191444MM15586
PathwayKEGG_MEDICUS_REFERENCE_WNT_SIGNALING_MODULATION_WNT_INHIBITOR

SFRP1 SFRP2

3.42e-0328442M47835
PathwayREACTOME_VISUAL_PHOTOTRANSDUCTION

AKR1C3 AKR1C4 AKR1C1

3.72e-03100443M27158
Pubmed

Studies on a Tyr residue critical for the binding of coenzyme and substrate in mouse 3(17)alpha-hydroxysteroid dehydrogenase (AKR1C21): structure of the Y224D mutant enzyme.

AKR1C3 AKR1C4 AKR1C1 AKR1C2

7.47e-12459420124700
Pubmed

Structure and activity of the murine type 5 17beta-hydroxysteroid dehydrogenase gene(1).

AKR1C3 AKR1C4 AKR1C1 AKR1C2

7.47e-12459410500239
Pubmed

Enzymatic properties of a member (AKR1C20) of the aldo-keto reductase family.

AKR1C3 AKR1C4 AKR1C1 AKR1C2

7.47e-12459416508162
Pubmed

AKR1C isoforms represent a novel cellular target for jasmonates alongside their mitochondrial-mediated effects.

AKR1C3 AKR1C4 AKR1C1 AKR1C2

7.47e-12459419487289
Pubmed

Cloning and chromosomal localization of mouse 20alpha-hydroxysteroid dehydrogenase gene.

AKR1C3 AKR1C4 AKR1C1 AKR1C2

7.47e-12459414967952
Pubmed

Assignment of HSD17B5 encoding type 5 17 beta-hydroxysteroid dehydrogenase to human chromosome bands 10p15-->p14 and mouse chromosome 13 region A2 by in situ hybridization: identification of a new syntenic relationship.

AKR1C3 AKR1C4 AKR1C1 AKR1C2

7.47e-12459410393440
Pubmed

Localization of 20alpha-hydroxysteroid dehydrogenase mRNA in mouse brain by in situ hybridization.

AKR1C3 AKR1C4 AKR1C1 AKR1C2

7.47e-12459415193432
Pubmed

Mouse Akr1cl gene product is a prostaglandin D2 11-ketoreductase with strict substrate specificity.

AKR1C3 AKR1C4 AKR1C1 AKR1C2

7.47e-12459431479646
Pubmed

Characterization and functional analysis of the 5'-flanking region of the mouse 20alpha-hydroxysteroid dehydrogenase gene.

AKR1C3 AKR1C4 AKR1C1 AKR1C2

7.47e-12459415222881
Pubmed

Isolation and characterization of a cDNA encoding mouse 3alpha-hydroxysteroid dehydrogenase: an androgen-inactivating enzyme selectively expressed in female tissues.

AKR1C3 AKR1C4 AKR1C1 AKR1C2

7.47e-12459416191478
Pubmed

Characterization of two isoforms of mouse 3(17)alpha-hydroxysteroid dehydrogenases of the aldo-keto reductase family.

AKR1C3 AKR1C4 AKR1C1 AKR1C2

7.47e-12459415577209
Pubmed

Identification of an interleukin-3-regulated aldoketo reductase gene in myeloid cells which may function in autocrine regulation of myelopoiesis.

AKR1C3 AKR1C4 AKR1C1 AKR1C2

7.47e-12459410702227
Pubmed

Crystal structures of mouse 17alpha-hydroxysteroid dehydrogenase (apoenzyme and enzyme-NADP(H) binary complex): identification of molecular determinants responsible for the unique 17alpha-reductive activity of this enzyme.

AKR1C3 AKR1C4 AKR1C1 AKR1C2

7.47e-12459417034817
Pubmed

Several distinct enzymes catalyze 20alpha-hydroxysteroid dehydrogenase activity in mouse liver and kidney.

AKR1C3 AKR1C4 AKR1C1 AKR1C2

7.47e-12459417629694
Pubmed

RECON-Dependent Inflammation in Hepatocytes Enhances Listeria monocytogenes Cell-to-Cell Spread.

AKR1C3 AKR1C4 AKR1C1 AKR1C2

7.47e-12459429764944
Pubmed

Cloning and characterization of two novel aldo-keto reductases (AKR1C12 and AKR1C13) from mouse stomach.

AKR1C3 AKR1C4 AKR1C1 AKR1C2

7.47e-12459410526179
Pubmed

Characterization of rat and mouse NAD+-dependent 3alpha/17beta/20alpha-hydroxysteroid dehydrogenases and identification of substrate specificity determinants by site-directed mutagenesis.

AKR1C3 AKR1C4 AKR1C1 AKR1C2

7.47e-12459417888864
Pubmed

Mouse 17alpha-hydroxysteroid dehydrogenase (AKR1C21) binds steroids differently from other aldo-keto reductases: identification and characterization of amino acid residues critical for substrate binding.

AKR1C3 AKR1C4 AKR1C1 AKR1C2

7.47e-12459417442338
Pubmed

Sensing of Bacterial Cyclic Dinucleotides by the Oxidoreductase RECON Promotes NF-κB Activation and Shapes a Proinflammatory Antibacterial State.

AKR1C3 AKR1C4 AKR1C1 AKR1C2

7.47e-12459428329705
Pubmed

Characterization of 17alpha-hydroxysteroid dehydrogenase activity (17alpha-HSD) and its involvement in the biosynthesis of epitestosterone.

AKR1C3 AKR1C4 AKR1C1 AKR1C2

7.47e-12459416018803
Pubmed

Reproductive phenotypes in mice with targeted disruption of the 20alpha-hydroxysteroid dehydrogenase gene.

AKR1C3 AKR1C4 AKR1C1 AKR1C2

7.47e-12459417272929
Pubmed

Structure of the G225P/G226P mutant of mouse 3(17)alpha-hydroxysteroid dehydrogenase (AKR1C21) ternary complex: implications for the binding of inhibitor and substrate.

AKR1C3 AKR1C4 AKR1C1 AKR1C2

7.47e-12459419237748
Pubmed

Involvement of 20alpha-hydroxysteroid dehydrogenase in the maintenance of pregnancy in mice.

AKR1C3 AKR1C4 AKR1C1 AKR1C2

7.47e-12459418667791
Pubmed

Mefenamic acid enhances anticancer drug sensitivity via inhibition of aldo-keto reductase 1C enzyme activity.

AKR1C3 AKR1C4 AKR1C1 AKR1C2

7.47e-12459428259989
Pubmed

Stereospecific reduction of 5β-reduced steroids by human ketosteroid reductases of the AKR (aldo-keto reductase) superfamily: role of AKR1C1-AKR1C4 in the metabolism of testosterone and progesterone via the 5β-reductase pathway.

AKR1C3 AKR1C4 AKR1C1 AKR1C2

7.47e-12459421521174
Pubmed

Molecular cloning of multiple cDNAs encoding human enzymes structurally related to 3 alpha-hydroxysteroid dehydrogenase.

AKR1C3 AKR1C4 AKR1C1 AKR1C2

7.47e-1245948274401
Pubmed

Crystallization and preliminary X-ray diffraction analysis of mouse 3(17)alpha-hydroxysteroid dehydrogenase.

AKR1C3 AKR1C4 AKR1C1 AKR1C2

7.47e-12459416511129
Pubmed

Identification of the oxidative 3alpha-hydroxysteroid dehydrogenase activity of rat Leydig cells as type II retinol dehydrogenase.

AKR1C3 AKR1C4 AKR1C1 AKR1C2

7.47e-12459410803568
Pubmed

AKR1C1 alleviates LPS‑induced ALI in mice by activating the JAK2/STAT3 signaling pathway.

AKR1C3 AKR1C4 AKR1C1 AKR1C2

7.47e-12459434590152
Pubmed

Localization of multiple human dihydrodiol dehydrogenase (DDH1 and DDH2) and chlordecone reductase (CHDR) genes in chromosome 10 by the polymerase chain reaction and fluorescence in situ hybridization.

AKR1C3 AKR1C4 AKR1C1 AKR1C2

7.47e-1245947789999
Pubmed

Timing of adrenal regression controlled by synergistic interaction between Sf1 SUMOylation and Dax1.

PIK3C2G AKR1C3 AKR1C4 AKR1C1 AKR1C2

9.27e-121259528893949
Pubmed

Molecular cloning and characterization of mouse estradiol 17 beta-dehydrogenase (A-specific), a member of the aldoketoreductase family.

AKR1C3 AKR1C4 AKR1C1 AKR1C2

3.73e-1155947737980
Pubmed

Retinaldehyde is a substrate for human aldo-keto reductases of the 1C subfamily.

AKR1C3 AKR1C4 AKR1C1 AKR1C2

3.73e-11559421851338
Pubmed

Preterm birth without progesterone withdrawal in 15-hydroxyprostaglandin dehydrogenase hypomorphic mice.

AKR1C3 AKR1C4 AKR1C1 AKR1C2

3.73e-11559417872381
Pubmed

Mouse 3alpha-hydroxysteroid dehydrogenase mRNA: a marker of lung maturity.

AKR1C3 AKR1C4 AKR1C1 AKR1C2

3.73e-11559417064890
Pubmed

Close kinship of human 20alpha-hydroxysteroid dehydrogenase gene with three aldo-keto reductase genes.

AKR1C3 AKR1C4 AKR1C1 AKR1C2

3.73e-11559410672042
Pubmed

Pregnane X receptor (PXR) deficiency promotes hepatocarcinogenesis via induction of Akr1c18 expression and prostaglandin F2α (PGF2α) levels.

AKR1C3 AKR1C4 AKR1C1 AKR1C2

3.73e-11559438788959
Pubmed

Characterization of brain neurons that express enzymes mediating neurosteroid biosynthesis.

AKR1C3 AKR1C4 AKR1C1 AKR1C2

3.73e-11559416984997
Pubmed

Down-regulation of neurosteroid biosynthesis in corticolimbic circuits mediates social isolation-induced behavior in mice.

AKR1C3 AKR1C4 AKR1C1 AKR1C2

3.73e-11559418003893
Pubmed

The Gαq/11-provoked induction of Akr1c18 in murine luteal cells is mediated by phospholipase C.

AKR1C3 AKR1C4 AKR1C1 AKR1C2

1.12e-10659429107092
Pubmed

Expression analysis of the aldo-keto reductases involved in the novel biosynthetic pathway of tetrahydrobiopterin in human and mouse tissues.

AKR1C3 AKR1C4 AKR1C1 AKR1C2

1.12e-10659419273550
Pubmed

Quantitative appreciation of steroidogenic gene expression in mouse tissues: new roles for type 2 5alpha-reductase, 20alpha-hydroxysteroid dehydrogenase and estrogen sulfotransferase.

AKR1C3 AKR1C4 AKR1C1 AKR1C2

1.12e-10659415860270
Pubmed

Regulation of progesterone levels during pregnancy and parturition by signal transducer and activator of transcription 5 and 20alpha-hydroxysteroid dehydrogenase.

AKR1C3 AKR1C4 AKR1C1 AKR1C2

1.12e-10659415471942
Pubmed

MEF2 and NR2F2 cooperate to regulate Akr1c14 gene expression in mouse MA-10 Leydig cells.

AKR1C3 AKR1C4 AKR1C1 AKR1C2

1.12e-10659426748576
Pubmed

Adrenal 20alpha-hydroxysteroid dehydrogenase in the mouse catabolizes progesterone and 11-deoxycorticosterone and is restricted to the X-zone.

AKR1C3 AKR1C4 AKR1C1 AKR1C2

1.12e-10659417122075
Pubmed

Decidual prolactin silences the expression of genes detrimental to pregnancy.

AKR1C3 AKR1C4 AKR1C1 AKR1C2

1.12e-10659417255200
Pubmed

The Steroidogenic Enzyme AKR1C3 Regulates Stability of the Ubiquitin Ligase Siah2 in Prostate Cancer Cells.

AKR1C3 AKR1C4 AKR1C1 AKR1C2

2.60e-10759426160177
Pubmed

Aldo-ketoreductase 1c19 ablation does not affect insulin secretion in murine islets.

AKR1C3 AKR1C4 AKR1C1 AKR1C2

2.60e-10759434843575
Pubmed

MicroRNA-200a serves a key role in the decline of progesterone receptor function leading to term and preterm labor.

AKR1C3 AKR1C4 AKR1C1 AKR1C2

2.60e-10759422529366
Pubmed

A phosphodiesterase 11 (Pde11a) knockout mouse expressed functional but reduced Pde11a: Phenotype and impact on adrenocortical function.

AKR1C3 AKR1C4 AKR1C1 AKR1C2

2.60e-10759433127481
Pubmed

A cluster of eight hydroxysteroid dehydrogenase genes belonging to the aldo-keto reductase supergene family on mouse chromosome 13.

AKR1C3 AKR1C4 AKR1C1 AKR1C2

2.60e-10759412562828
Pubmed

17Beta-HSD type 5 expression and the emergence of differentiated epithelial Type II cells in fetal lung: a novel role for androgen during the surge of surfactant.

AKR1C3 AKR1C4 AKR1C1 AKR1C2

2.60e-10759416337335
Pubmed

Androgen Receptor Is Dispensable for X-Zone Regression in the Female Adrenal but Regulates Post-Partum Corticosterone Levels and Protects Cortex Integrity.

AKR1C3 AKR1C4 AKR1C1 AKR1C2

5.20e-10859433584538
Pubmed

Naturally occurring variants of human aldo-keto reductases with reduced in vitro metabolism of daunorubicin and doxorubicin.

AKR1C3 AKR1C4 AKR1C1 AKR1C2

5.20e-10859420837989
Pubmed

Cloning of mouse 17beta-hydroxysteroid dehydrogenase type 2, and analysing expression of the mRNAs for types 1, 2, 3, 4 and 5 in mouse embryos and adult tissues.

AKR1C3 AKR1C4 AKR1C1 AKR1C2

5.20e-1085949224647
Pubmed

Conditional mutagenesis of Gata6 in SF1-positive cells causes gonadal-like differentiation in the adrenal cortex of mice.

PIK3C2G AKR1C3 AKR1C4 AKR1C1 AKR1C2

9.27e-102759523471215
Pubmed

Decrease in the T-box1 gene expression in embryonic brain and adult hippocampus of down syndrome mouse models.

AKR1C3 AKR1C4 AKR1C1 AKR1C2

9.35e-10959433348080
Pubmed

The E3 ubiquitin ligase Siah1 regulates adrenal gland organization and aldosterone secretion.

PIK3C2G AKR1C3 AKR1C4 AKR1C1 AKR1C2

1.13e-092859529212953
Pubmed

Lack of placental neurosteroid alters cortical development and female somatosensory function.

AKR1C3 AKR1C4 AKR1C1 AKR1C2

1.56e-091059436313771
Pubmed

Endogenous biotin as a marker of adrenocortical cells with steroidogenic potential.

AKR1C3 AKR1C4 AKR1C1 AKR1C2

3.66e-091259421256921
Pubmed

A Novel Population of Inner Cortical Cells in the Adrenal Gland That Displays Sexually Dimorphic Expression of Thyroid Hormone Receptor-β1.

AKR1C3 AKR1C4 AKR1C1 AKR1C2

3.66e-091259425774556
Pubmed

Aldo-keto reductase 1C subfamily genes in skin are UV-inducible: possible role in keratinocytes survival.

AKR1C3 AKR1C1 AKR1C2

4.64e-09359319320734
Pubmed

Aldo-keto reductases protect metastatic melanoma from ER stress-independent ferroptosis.

AKR1C3 AKR1C1 AKR1C2

4.64e-09359331780644
Pubmed

Distribution of 3 alpha-hydroxysteroid dehydrogenase in rat brain and molecular cloning of multiple cDNAs encoding structurally related proteins in humans.

AKR1C3 AKR1C4 AKR1C1

4.64e-0935937626489
Pubmed

Aldo-keto reductases AKR1C1, AKR1C2 and AKR1C3 may enhance progesterone metabolism in ovarian endometriosis.

AKR1C3 AKR1C1 AKR1C2

4.64e-09359321232532
Pubmed

Altered expression of 3 alpha-hydroxysteroid dehydrogenases in human glaucomatous optic nerve head astrocytes.

AKR1C3 AKR1C1 AKR1C2

4.64e-09359313678667
Pubmed

The Diet1 locus confers protection against hypercholesterolemia through enhanced bile acid metabolism.

AKR1C3 AKR1C4 AKR1C1 AKR1C2

5.28e-091359411682476
Pubmed

Genetic determinants modulate susceptibility to pregnancy-associated tumourigenesis in a recombinant line of Min mice.

AKR1C3 AKR1C4 AKR1C1 AKR1C2

5.28e-091359417062636
Pubmed

A link between lung androgen metabolism and the emergence of mature epithelial type II cells.

AKR1C3 AKR1C4 AKR1C1 AKR1C2

5.28e-091359415117747
Pubmed

Ontogeny of adrenal-like glucocorticoid synthesis pathway and of 20α-hydroxysteroid dehydrogenase in the mouse lung.

AKR1C3 AKR1C4 AKR1C1 AKR1C2

5.28e-091359424580729
Pubmed

Shh signaling regulates adrenocortical development and identifies progenitors of steroidogenic lineages.

AKR1C3 AKR1C4 AKR1C1 AKR1C2

7.38e-091459419955443
Pubmed

Placental endocrine function shapes cerebellar development and social behavior.

AKR1C3 AKR1C4 AKR1C1 AKR1C2

7.38e-091459434400844
Pubmed

Chromosomal organization of candidate genes involved in cholesterol gallstone formation: a murine gallstone map.

AKR1C3 AKR1C4 MUC5AC AKR1C1 AKR1C2

1.72e-084759511208732
Pubmed

Targeted Disruption of Lats1 and Lats2 in Mice Impairs Adrenal Cortex Development and Alters Adrenocortical Cell Fate.

AKR1C3 AKR1C4 AKR1C1 AKR1C2

1.75e-081759432243503
Pubmed

Functional dynamics of H3K9 methylation during meiotic prophase progression.

AKR1C3 AKR1C4 AKR1C1 AKR1C2

2.84e-081959417599069
Pubmed

A broadly applicable high-throughput screening strategy identifies new regulators of Dlg4 (Psd-95) alternative splicing.

AKR1C3 AKR1C4 AKR1C1 AKR1C2

3.55e-082059423636947
Pubmed

WT1 maintains adrenal-gonadal primordium identity and marks a population of AGP-like progenitors within the adrenal gland.

AKR1C3 AKR1C4 AKR1C1 AKR1C2

3.55e-082059424135228
Pubmed

Expression of progesterone metabolizing enzyme genes (AKR1C1, AKR1C2, AKR1C3, SRD5A1, SRD5A2) is altered in human breast carcinoma.

AKR1C3 AKR1C1 AKR1C2

4.63e-08559315212687
Pubmed

Tbx18 expression demarcates multipotent precursor populations in the developing urogenital system but is exclusively required within the ureteric mesenchymal lineage to suppress a renal stromal fate.

AKR1C3 AKR1C4 AKR1C1 AKR1C2

6.45e-082359423685333
Pubmed

Steroid receptor coactivators 1 and 2 mediate fetal-to-maternal signaling that initiates parturition.

AKR1C3 AKR1C4 AKR1C1 AKR1C2

9.20e-082559426098214
Pubmed

Histone H3 lysine 9 methyltransferases, G9a and GLP are essential for cardiac morphogenesis.

AKR1C3 AKR1C4 AKR1C1 AKR1C2

1.09e-072659423892084
Pubmed

Fetal onset of aberrant gene expression relevant to pulmonary carcinogenesis in lung adenocarcinoma development induced by in utero arsenic exposure.

AKR1C3 AKR1C4 AKR1C1 AKR1C2

1.27e-072759417077188
Pubmed

Identification of differentially expressed genes in mouse spermatogenesis.

AKR1C3 AKR1C4 AKR1C1 AKR1C2

1.27e-072759414581517
Pubmed

MRAP deficiency impairs adrenal progenitor cell differentiation and gland zonation.

AKR1C3 AKR1C4 AKR1C1 AKR1C2

1.48e-072859429879378
Pubmed

Eliminating SF-1 (NR5A1) sumoylation in vivo results in ectopic hedgehog signaling and disruption of endocrine development.

AKR1C3 AKR1C4 AKR1C1 AKR1C2

1.48e-072859421820362
Pubmed

Genetic variation in the progesterone receptor and metabolism pathways and hormone therapy in relation to breast cancer risk.

AKR1C3 AKR1C1 AKR1C2

1.62e-07759319846565
Pubmed

Constitutive expression of Steroidogenic factor-1 (NR5A1) disrupts ovarian functions, fertility, and metabolic homeostasis in female mice.

AKR1C3 AKR1C4 AKR1C1 AKR1C2

2.59e-073259434288113
Pubmed

An expression profile analysis of ES cell-derived definitive endodermal cells and Pdx1-expressing cells.

AKR1C3 AKR1C4 AKR1C1 AKR1C2

4.73e-073759421362171
Pubmed

Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

USP34 TRIM2 CHST15 SSPOP ZEB2

1.00e-061055959628581
Pubmed

WT1-mediated gene regulation in early urogenital ridge development.

AKR1C3 AKR1C4 AKR1C1 AKR1C2

1.06e-064559418391535
Pubmed

TWIST1 and chromatin regulatory proteins interact to guide neural crest cell differentiation.

NSD1 CHD8 CHD6 ZEB2 NSD3

1.21e-0610959533554859
Pubmed

Diabetes risk gene and Wnt effector Tcf7l2/TCF4 controls hepatic response to perinatal and adult metabolic demand.

AKR1C3 AKR1C4 AKR1C1 AKR1C2

1.90e-065259423260145
Pubmed

Foxl2 functions in sex determination and histogenesis throughout mouse ovary development.

AKR1C3 AKR1C4 AKR1C1 AKR1C2

2.39e-065559419538736
Pubmed

Molecular cloning of two human liver 3 alpha-hydroxysteroid/dihydrodiol dehydrogenase isoenzymes that are identical with chlordecone reductase and bile-acid binder.

AKR1C4 AKR1C1

2.83e-0625928172617
Pubmed

Relationship of human liver dihydrodiol dehydrogenases to hepatic bile-acid-binding protein and an oxidoreductase of human colon cells.

AKR1C1 AKR1C2

2.83e-0625928573067
Pubmed

Substrate specificity, gene structure, and tissue-specific distribution of multiple human 3 alpha-hydroxysteroid dehydrogenases.

AKR1C3 AKR1C4

2.83e-0625927650035
Pubmed

Wnt modulators, SFRP-1, and SFRP-2 are expressed in osteoblasts and differentially regulate hematopoietic stem cells.

SFRP1 SFRP2

2.83e-06259219778523
Pubmed

Structure of the human 3alpha-hydroxysteroid dehydrogenase type 3 in complex with testosterone and NADP at 1.25-A resolution.

AKR1C1 AKR1C2

2.83e-06259211514561
Pubmed

Selective loss of AKR1C1 and AKR1C2 in breast cancer and their potential effect on progesterone signaling.

AKR1C1 AKR1C2

2.83e-06259215492289
Pubmed

Local androgen inactivation in abdominal visceral adipose tissue.

AKR1C3 AKR1C2

2.83e-06259214671194
InteractionAKR1C4 interactions

AKR1C3 AKR1C4 AKR1C1 AKR1C2

4.29e-098584int:AKR1C4
InteractionAKR1C1 interactions

AKR1C3 AKR1C4 AKR1C1 AKR1C2

2.89e-0720584int:AKR1C1
InteractionSFRP1 interactions

SFRP1 SFRP2 PUS7L DNMT1

7.47e-0725584int:SFRP1
InteractionAKR1C3 interactions

AKR1C3 AKR1C4 AKR1C1 AKR1C2

3.80e-0637584int:AKR1C3
InteractionAKR1C2 interactions

AKR1C3 AKR1C4 AKR1C1 AKR1C2

1.89e-0555584int:AKR1C2
InteractionZNF707 interactions

USP34 ZNF689 CHD8 LTBP2

7.90e-0579584int:ZNF707
InteractionSFRP5 interactions

SFRP1 SFRP2

1.21e-046582int:SFRP5
InteractionTWIST1 interactions

NSD1 CHD8 CHD6 ZEB2 NSD3

1.29e-04170585int:TWIST1
InteractionUBE2W interactions

TRIM2 AKR1C3 UBOX5 TRIM3

1.68e-0496584int:UBE2W
Cytoband10p15-p14

AKR1C3 AKR1C1 AKR1C2

4.02e-08659310p15-p14
CytobandEnsembl 112 genes in cytogenetic band chr10p15

AKR1C3 AKR1C4 AKR1C1 AKR1C2

5.79e-0690594chr10p15
Cytoband13q33.1

TEX30 CCDC168

1.06e-041259213q33.1
Cytoband11p15.5

PIDD1 MUC5AC TRIM3

4.84e-0411859311p15.5
Cytoband4q31.3

SFRP2 TRIM2

7.37e-04315924q31.3
CytobandXq21.1

ZNF711 HDX

8.36e-0433592Xq21.1
CytobandEnsembl 112 genes in cytogenetic band chr13q33

TEX30 CCDC168

2.31e-0355592chr13q33
Cytoband7q36.1

ZNF425 SSPOP

4.13e-03745927q36.1
GeneFamilyAldo-keto reductases

AKR1C3 AKR1C4 AKR1C1 AKR1C2

4.08e-0815444399
GeneFamilySecreted frizzled-related proteins

SFRP1 SFRP2

5.76e-055442733
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZHX2 ZEB2

5.96e-0415442529
GeneFamilyPWWP domain containing

NSD1 NSD3

1.30e-03224421147
GeneFamilyZinc fingers C2H2-type|Lysine methyltransferases|PR/SET domain family

NSD1 NSD3

3.09e-0334442487
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZNF711 ZNF425 ZNF689 GLIS3 ZHX2 ZEB2

7.49e-0371844628
CoexpressionIRITANI_MAD1_TARGETS_UP

AKR1C3 AKR1C4 AKR1C1 AKR1C2

5.39e-0817594MM826
CoexpressionLIN_TUMOR_ESCAPE_FROM_IMMUNE_ATTACK

AKR1C3 AKR1C4 AKR1C1 AKR1C2

2.38e-0724594MM766
CoexpressionGAUSSMANN_MLL_AF4_FUSION_TARGETS_C_DN

AKR1C3 AKR1C4 AKR1C1 AKR1C2

2.83e-0725594MM480
CoexpressionBYSTRYKH_HEMATOPOIESIS_STEM_CELL_SCP2_QTL_TRANS

AKR1C3 AKR1C4 AKR1C1 AKR1C2

6.07e-0730594MM853
CoexpressionSHETH_LIVER_CANCER_VS_TXNIP_LOSS_PAM3

TSPAN8 AKR1C3 AKR1C4 AKR1C1 AKR1C2

9.64e-0779595MM535
CoexpressionDESCARTES_ORGANOGENESIS_INTERMEDIATE_MESODERM

AKR1C3 AKR1C4 AKR1C1 AKR1C2

1.29e-0636594MM3660
CoexpressionNAKAYAMA_SOFT_TISSUE_TUMORS_PCA2_DN

SFRP1 TFPI2 AKR1C3 AKR1C1 SVEP1

1.39e-0685595M1451
CoexpressionWANG_IMMORTALIZED_BY_HOXA9_AND_MEIS1_UP

AKR1C3 AKR1C4 AKR1C1 AKR1C2

1.45e-0637594MM630
CoexpressionVARELA_ZMPSTE24_TARGETS_DN

AKR1C3 AKR1C4 AKR1C1 AKR1C2

3.22e-0645594MM1173
CoexpressionNABA_ECM_GLYCOPROTEINS

CRIM1 SLIT1 LTBP2 USH2A SSPOP SVEP1

5.25e-06196596M3008
CoexpressionRAO_BOUND_BY_SALL4_ISOFORM_A

ARHGAP6 TSPAN8 AKR1C3 AKR1C4 AKR1C1 AKR1C2

7.79e-06210596MM958
CoexpressionMARSON_FOXP3_TARGETS_DN

AKR1C3 AKR1C4 AKR1C1 AKR1C2

1.03e-0560594MM847
CoexpressionNADLER_HYPERGLYCEMIA_AT_OBESITY

AKR1C3 AKR1C4 AKR1C1 AKR1C2

1.50e-0566594MM631
CoexpressionGOLDRATH_IMMUNE_MEMORY

AKR1C3 AKR1C4 AKR1C1 AKR1C2

1.79e-0569594MM621
CoexpressionBREDEMEYER_RAG_SIGNALING_NOT_VIA_ATM_UP

AKR1C3 AKR1C4 AKR1C1 AKR1C2

2.37e-0574594MM769
CoexpressionNABA_CORE_MATRISOME

CRIM1 SLIT1 LTBP2 USH2A SSPOP SVEP1

3.57e-05275596M5884
CoexpressionGSE3920_IFNA_VS_IFNB_TREATED_ENDOTHELIAL_CELL_DN

CRIM1 CHST15 DGKH ZEB2 NSD3

3.64e-05166595M6701
CoexpressionFLECHNER_BIOPSY_KIDNEY_TRANSPLANT_OK_VS_DONOR_UP

MTMR4 SFRP1 TRIM2 TSPAN8 AKR1C3 AKR1C1 ZEB2 TNFRSF11B

3.88e-05568598M4023
CoexpressionHOFFMANN_PRE_BI_TO_LARGE_PRE_BII_LYMPHOCYTE_DN

AKR1C3 AKR1C4 AKR1C1 AKR1C2

4.09e-0585594MM802
CoexpressionZAMORA_NOS2_TARGETS_DN

AKR1C3 AKR1C4 AKR1C1 AKR1C2

4.90e-0589594MM690
CoexpressionTRAVAGLINI_LUNG_ADVENTITIAL_FIBROBLAST_CELL

SFRP1 SFRP2 AKR1C3 AKR1C1 AKR1C2 SVEP1

5.37e-05296596M41675
CoexpressionBAKKER_FOXO3_TARGETS_DN

CHST15 AKR1C3 AKR1C4 AKR1C1 AKR1C2

6.58e-05188595MM904
CoexpressionNABA_ECM_GLYCOPROTEINS

CRIM1 SLIT1 LTBP2 SSPOP SVEP1

7.09e-05191595MM17059
CoexpressionOHM_EMBRYONIC_CARCINOMA_UP

SFRP1 SFRP2

7.43e-056592M6244
CoexpressionFOSTER_KDM1A_TARGETS_UP

TSPAN8 AKR1C3 DEFB135 AKR1C4 AKR1C1 AKR1C2

7.85e-05317596MM956
CoexpressionYAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_6

AKR1C3 AKR1C4 AKR1C1 AKR1C2

8.35e-05102594MM872
CoexpressionGSE32986_GMCSF_VS_GMCSF_AND_CURDLAN_HIGHDOSE_STIM_DC_DN

TRIM2 CHD8 DGKH ZHX2 NSD3

8.41e-05198595M8624
CoexpressionGSE15750_DAY6_VS_DAY10_TRAF6KO_EFF_CD8_TCELL_DN

MTMR4 AGO1 CRIM1 ZHX2 ZEB2

8.61e-05199595M3583
CoexpressionNABA_MATRISOME

SFRP1 SFRP2 CRIM1 ADAM15 SLIT1 LTBP2 USH2A SSPOP MUC5AC SVEP1

8.88e-0510265910M5889
CoexpressionRICKMAN_HEAD_AND_NECK_CANCER_A

ZNF711 SFRP1 TSPAN8 TNFRSF11B

9.34e-05105594M14228
CoexpressionDURCHDEWALD_SKIN_CARCINOGENESIS_UP

AKR1C3 AKR1C4 AKR1C1 AKR1C2

1.16e-04111594MM705
CoexpressionRAY_TUMORIGENESIS_BY_ERBB2_CDC25A_UP

CFAP251 AKR1C3 AKR1C4 AKR1C1 AKR1C2

1.35e-04219595MM1237
CoexpressionTABULA_MURIS_SENIS_MESENTERIC_ADIPOSE_TISSUE_MESENCHYMAL_STEM_CELL_OF_ADIPOSE_AGEING

SFRP1 SFRP2 AKR1C3 AKR1C4 AKR1C1 AKR1C2 B3GAT3 NSD3

1.43e-04685598MM3782
CoexpressionBUSSLINGER_GASTRIC_MATURE_PIT_CELLS

TSPAN8 AKR1C3 PSAPL1 AKR1C1 AKR1C2

1.50e-04224595M40013
CoexpressionSERVITJA_ISLET_HNF1A_TARGETS_DN

AKR1C3 AKR1C4 AKR1C1 AKR1C2

1.62e-04121594MM935
CoexpressionIVANOVA_HEMATOPOIESIS_STEM_CELL_LONG_TERM

CRIM1 AKR1C3 AKR1C4 AKR1C1 AKR1C2

1.63e-04228595MM1014
CoexpressionDELYS_THYROID_CANCER_DN

MTMR4 SFRP1 SSPOP AKR1C1 TNFRSF11B

1.80e-04233595M13273
CoexpressionTRAVAGLINI_LUNG_MUCOUS_CELL

TFPI2 TSPAN8 AKR1C1 AKR1C2

1.83e-04125594M41656
CoexpressionSCHLESINGER_METHYLATED_IN_COLON_CANCER

SFRP1 SFRP2

2.22e-0410592M821
CoexpressionBROWN_MYELOID_CELL_DEVELOPMENT_DN

AKR1C3 AKR1C4 AKR1C1 AKR1C2

2.67e-04138594MM1151
CoexpressionMIKKELSEN_MEF_LCP_WITH_H3K4ME3

AKR1C3 AKR1C4 AKR1C1 AKR1C2

2.98e-04142594MM840
CoexpressionMCBRYAN_PUBERTAL_BREAST_5_6WK_UP

AKR1C3 AKR1C4 AKR1C1 AKR1C2

3.06e-04143594MM989
CoexpressionNABA_CORE_MATRISOME

CRIM1 SLIT1 LTBP2 SSPOP SVEP1

3.55e-04270595MM17057
CoexpressionGOZGIT_ESR1_TARGETS_DN

TRIM2 CHST15 AKR1C3 CHD8 LTBP2 ZHX2 AKR1C1 TNFRSF11B

3.62e-04786598M10961
CoexpressionSERVITJA_LIVER_HNF1A_TARGETS_UP

AKR1C3 AKR1C4 AKR1C1 AKR1C2

3.67e-04150594MM936
CoexpressionGSE14699_NAIVE_VS_DELETIONAL_TOLERANCE_CD8_TCELL_UP

CRIM1 CHST15 ZHX2 NSD3

3.86e-04152594M2938
CoexpressionNABA_MATRISOME

SFRP1 SFRP2 CRIM1 ADAM15 SLIT1 LTBP2 SSPOP MUC5AC SVEP1

3.96e-041008599MM17056
CoexpressionINGRAM_SHH_TARGETS_UP

AKR1C3 AKR1C4 AKR1C1 AKR1C2

4.26e-04156594MM550
CoexpressionGSE4984_GALECTIN1_VS_LPS_STIM_DC_UP

CHD8 ZHX2 B3GAT3 NSD3

4.58e-04159594M6502
CoexpressionBENPORATH_OCT4_TARGETS

SFRP1 SFRP2 REST ZHX2 ZEB2

4.92e-04290595M17183
CoexpressionENGELMANN_CANCER_PROGENITORS_DN

AKR1C3 AKR1C1 AKR1C2

5.11e-0469593M9246
CoexpressionBUSSLINGER_GASTRIC_IMMATURE_PIT_CELLS

TSPAN8 AKR1C3 AKR1C1 AKR1C2

5.26e-04165594M40012
CoexpressionNFE2L2.V2

AKR1C3 AKR1C4 TERT MUC5AC AKR1C1 TNFRSF11B

6.42e-04469596M2870
CoexpressionMIKKELSEN_MCV6_LCP_WITH_H3K4ME3

AKR1C3 AKR1C4 AKR1C1 AKR1C2

6.42e-04174594MM836
CoexpressionGSE3920_IFNA_VS_IFNG_TREATED_FIBROBLAST_UP

CRIM1 CHST15 DGKH ZEB2

6.56e-04175594M6690
CoexpressionLAKE_ADULT_KIDNEY_C4_PROXIMAL_TUBULE_EPITHELIAL_CELLS_S2

ARHGAP6 CRIM1 GLIS3 DGKH

6.70e-04176594M39223
CoexpressionBYSTRYKH_HEMATOPOIESIS_STEM_CELL_QTL_TRANS

PIK3C2G AKR1C3 SLC25A44 AKR1C4 MUC5AC AKR1C1 AKR1C2 B3GAT3

7.12e-04871598MM1005
CoexpressionBENPORATH_NOS_TARGETS

SFRP1 SFRP2 REST ZEB2

7.14e-04179594M14573
CoexpressionTHUM_MIR21_TARGETS_HEART_DISEASE_UP

LTBP2 SVEP1

7.45e-0418592MM1241
CoexpressionTHUM_MIR21_TARGETS_HEART_DISEASE_UP

LTBP2 SVEP1

7.45e-0418592M13796
CoexpressionLI_WILMS_TUMOR_VS_FETAL_KIDNEY_1_UP

TRIM2 CRIM1 AKR1C3 ZEB2

7.76e-04183594M12621
CoexpressionWU_CELL_MIGRATION

CHST15 TFPI2 AKR1C3 AKR1C1

7.76e-04183594M2001
CoexpressionSMID_BREAST_CANCER_RELAPSE_IN_BONE_DN

USP34 SFRP1 TRIM2 AKR1C1 TNFRSF11B

8.11e-04324595M2700
CoexpressionMURARO_PANCREAS_MESENCHYMAL_STROMAL_CELL

SFRP1 SFRP2 CHST15 TFPI2 LTBP2 REST ZEB2

8.19e-04681597M39175
CoexpressionSENESE_HDAC3_TARGETS_UP

USP34 SFRP1 AKR1C3 LTBP2 AKR1C1 TNFRSF11B

8.50e-04495596M8451
ToppCellCOVID-19-kidney-Fibroblast-1|COVID-19 / Disease (COVID-19 only), tissue and cell type

CFAP251 SFRP1 CHST15 GLIS3 RXFP1 SVEP1

1.78e-0718759676bfe8c42430a230a8bdf299575c444fb7780f24
ToppCellIPF-Epithelial-Goblet|IPF / Disease state, Lineage and Cell class

TRIM2 TSPAN8 GLIS3 MUC5AC AKR1C1 AKR1C2

1.96e-07190596e41dd5a997ad9952810ffecb57737c03ea1d88b3
ToppCellLV-01._Fibroblast_I|LV / Chamber and Cluster_Paper

ARHGAP6 GLIS3 LTBP2 AKR1C1 AKR1C2 SVEP1

2.15e-07193596dc17f3b9758936d428cf17f77a1ce6d4c479b165
ToppCellCOVID-19-kidney-Fibroblast-2|COVID-19 / Disease (COVID-19 only), tissue and cell type

SFRP1 CHST15 GLIS3 RXFP1 ZEB2 SVEP1

2.28e-071955963d62ce1c696f47d4d7eb0c5bb0eec2c24b122bb2
ToppCellproximal-Epithelial-Mucous-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

TRIM2 TFPI2 TSPAN8 MUC5AC AKR1C1 AKR1C2

2.57e-07199596baac580484124b7c36717b607adcf2cb446e631d
ToppCellproximal-Epithelial-Mucous|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

TRIM2 TFPI2 TSPAN8 MUC5AC AKR1C1 AKR1C2

2.57e-0719959615ba36fa6ad73d0e959e42f18d7acbc14e310dc9
ToppCellproximal-3-Epithelial-Mucous|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

TRIM2 TFPI2 TSPAN8 MUC5AC AKR1C1 AKR1C2

2.57e-071995963018378860de084662be0cc46fce421db3bb9ec9
ToppCellTransplant_Alveoli_and_parenchyma-Mesenchymal-Fibroblasts|Mesenchymal / Tissue, Lineage and Cell class of Lung Cells from 10X

SFRP1 SFRP2 TSPAN8 AKR1C3 AKR1C1 SVEP1

2.57e-07199596f19c683f38bca3bfee40396f27423441051dec67
ToppCell(5)_Fibroblast-E|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

SFRP1 SFRP2 SLIT1 TSPAN8 AKR1C1 SVEP1

2.65e-0720059675e5ecb05e965e24d569aa2ef5cdf740b1528c06
ToppCellClub_cells-Donor_04|World / lung cells shred on cell class, cell subclass, sample id

TRIM2 AMIGO3 TSPAN8 GLIS3 AKR1C1

2.36e-06161595342f5c61d37df61b35c18f5d258043a8f5cef629
ToppCell367C-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)|367C / Donor, Lineage, Cell class and subclass (all cells)

SFRP1 SFRP2 TFPI2 LTBP2 AKR1C1

2.99e-0616959547fd4adfe54777e69a0fabf8bd34f26223f63275
ToppCell367C-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)-|367C / Donor, Lineage, Cell class and subclass (all cells)

SFRP1 SFRP2 TFPI2 LTBP2 AKR1C1

2.99e-06169595e09259d62cd3e42f0919f231ed1164db59b0b6c3
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_PRSS12|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TEX30 PIK3C2G GLIS3 DGKH CCDC168

3.36e-061735958ac2e9d39c0f76e674f8bd59d1da246bab4867c8
ToppCell356C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)-|356C / Donor, Lineage, Cell class and subclass (all cells)

TFPI2 TSPAN8 MUC5AC AKR1C1 AKR1C2

3.55e-06175595af9c5104c86231cfdb93a0f7d7032379efaa009e
ToppCell356C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)|356C / Donor, Lineage, Cell class and subclass (all cells)

TFPI2 TSPAN8 MUC5AC AKR1C1 AKR1C2

3.55e-061755954bfae78ac3a2cb9404382aae96d291504a9cfa14
ToppCellChildren_(3_yrs)-Epithelial-lung_goblet_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

TRIM2 TSPAN8 GLIS3 MUC5AC AKR1C1

4.30e-061825953f1a666fe27dd7529c114539ed5f6b8ca585c875
ToppCellControl-Epithelial-Goblet|Epithelial / Disease state, Lineage and Cell class

TFPI2 TSPAN8 MUC5AC AKR1C1 AKR1C2

4.42e-06183595bdd461349a1ef43a015843937d26e8d3571ecc22
ToppCellCOPD-Epithelial-Goblet|World / Disease state, Lineage and Cell class

TRIM2 TSPAN8 GLIS3 AKR1C1 AKR1C2

4.78e-06186595d75fe7640a4b2c450c9759a1b3c3ef2a087f0092
ToppCell5'-Adult-SmallIntestine-Epithelial-Tuft-related-Microfold_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TSPAN8 AKR1C3 MUC5AC AKR1C1 AKR1C2

4.78e-061865956d8dd6d0403d149cb6edb346581fe6c248036785
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature3_(17)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ARHGAP6 SFRP2 GLIS3 ZEB2 SVEP1

4.91e-06187595a9316e2818217ec5feae9cf8816f7249803caee6
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP6 SFRP1 TRIM2 LTBP2 RP1

4.91e-061875957ea8731288e2a99f45e3958590ee1d76f49ae888
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP6 SFRP1 TRIM2 LTBP2 RP1

5.04e-061885952ee64bc73a2251fd9f374be759b442cf4ed0d19e
ToppCellCOVID-19-lung-Secretory|lung / Disease (COVID-19 only), tissue and cell type

TRIM2 TSPAN8 GLIS3 MUC5AC AKR1C1

5.17e-0618959584d48e3ed25bebb8bb8074b3a2c5e2e88cff7f25
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP6 SFRP1 TRIM2 LTBP2 RP1

5.30e-061905953dcadabbefe0128a5f30ab51234f049ab4d870c6
ToppCellCOVID-19-Epithelial_cells-Airway_goblet|COVID-19 / group, cell type (main and fine annotations)

TRIM2 TSPAN8 GLIS3 MUC5AC AKR1C1

5.30e-0619059551ca9ef4df3220487152fcf684147730637c7cc1
ToppCellIPF-Epithelial-Goblet|World / Disease state, Lineage and Cell class

TRIM2 TSPAN8 GLIS3 MUC5AC AKR1C1

5.30e-06190595c29dabf0826663b9d6df51a7af9b76592090e44c
ToppCell3'-Distal_airway-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SFRP1 SFRP2 TFPI2 AKR1C1 SVEP1

5.44e-06191595f5ce33af56178333730be308253943c54a0724cf
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP6 SFRP1 TRIM2 LTBP2 RP1

5.44e-06191595963f4f2e852bbb4faf070aafb0d368297abacd3b
ToppCellCOVID-19-kidney-TAL|COVID-19 / Disease (COVID-19 only), tissue and cell type

ARHGAP6 SFRP1 TRIM2 GLIS3 RP1

5.44e-06191595fe55475ce0666ab5122447a813dc2369e24947b8
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP6 SFRP1 TRIM2 GLIS3 DGKH

5.44e-061915959032aa974aa1b7b1095b8d1b58dcb087358a5001
ToppCellCOVID-19-kidney-Mito-rich_Distal|COVID-19 / Disease (COVID-19 only), tissue and cell type

ARHGAP6 SFRP1 TRIM2 GLIS3 RP1

5.44e-061915950965f621ebcd92ccdeb21cc27022180ce3cfe910
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP6 SFRP1 TRIM2 GLIS3 DGKH

5.44e-061915955717809a1476c20f65bce722c5a57cff92ee0d7a
ToppCellNS-critical-d_16-33-Epithelial-Secretory-diff|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

TFPI2 TSPAN8 MUC5AC AKR1C1 AKR1C2

5.58e-0619259502b11233b4da2d85b96498b3c6e22e3a31b3d049
ToppCell390C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

TFPI2 TSPAN8 AKR1C3 AKR1C1 AKR1C2

5.58e-061925955d24bb6c6c17a6b803b241d065b31896a7d86c37
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP6 SFRP1 TRIM2 LTBP2 RP1

5.58e-06192595562df5e87038c500dd3a003fe5374cb31946b145
ToppCell390C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

TFPI2 TSPAN8 AKR1C3 AKR1C1 AKR1C2

5.58e-06192595c6795ceba90f1a5d441dff92a737b9c7d28b06b0
ToppCell(7)_Epithelial_cells-(7)_Epithelial-G_(Club-Clara_cells)|(7)_Epithelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)

TFPI2 TSPAN8 MUC5AC AKR1C1 AKR1C2

5.58e-06192595c7c232545fad8ad327ab94bd0def8dc5daacd03d
ToppCell343B-Epithelial_cells-Epithelial-G_(Club-Clara_cells)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

TFPI2 TSPAN8 MUC5AC AKR1C1 AKR1C2

5.72e-061935958ede7038a222c7e7ecaf7e86520823cf606cbee7
ToppCell343B-Epithelial_cells-Epithelial-G_(Club-Clara_cells)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

TFPI2 TSPAN8 MUC5AC AKR1C1 AKR1C2

5.72e-061935950e7d7adfaa7191e34038fcda6677561ae13934eb
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_secretory-Secretory_Goblet|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TRIM2 TSPAN8 MUC5AC AKR1C1 AKR1C2

5.87e-06194595e0228f593c3493175962a4817500d4337ddc4e88
ToppCellIPF-Stromal-Fibroblast|Stromal / Disease state, Lineage and Cell class

SFRP1 SFRP2 AKR1C1 AKR1C2 SVEP1

5.87e-06194595da3e1d39575969a069ef43e552afe94b2f441d0b
ToppCellIPF-Multiplet-Multiplet|World / Disease state, Lineage and Cell class

CFAP251 TRIM2 GLIS3 RP1 CFAP61

6.01e-0619559521dbdc803c6947024dc2416e9e21c2ef0af9bc31
ToppCellEpithelial_cells-Club_cells|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id

TRIM2 TSPAN8 MUC5AC AKR1C1 AKR1C2

6.01e-06195595b758676abfc4e6930b696d270ecc0ea461b87a54
ToppCellfacs-Skin-nan-18m-Epithelial-outer_bulge|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SFRP1 CRIM1 LTBP2 SVEP1 TNFRSF11B

6.01e-06195595ba7cb80deb872c9184769f0dd57855c3c6a432bf
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_secretory|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TRIM2 TSPAN8 MUC5AC AKR1C1 AKR1C2

6.01e-06195595e7230a849ea31e6eef9bc6f5468938499450582d
ToppCellPCW_05-06-Mesenchymal|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

ARHGAP6 SFRP1 SFRP2 ZEB2 SVEP1

6.17e-06196595dca52c57ba35d9395cdbca8b881f12ece721b10f
ToppCellNasal_Brush-Epithelial-Goblet_1|Nasal_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

TFPI2 ADAM15 TSPAN8 MUC5AC AKR1C2

6.17e-06196595e16f0831f1f677b28e4a8014f0aede7e713d4f04
ToppCellCOPD-Stromal-Fibroblast|Stromal / Disease state, Lineage and Cell class

SFRP1 SFRP2 TFPI2 AKR1C1 AKR1C2

6.17e-061965954930eeb303d174c28fd91021723e26fdf1af9170
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP6 SFRP1 TRIM2 TSPAN8 RP1

6.17e-06196595e02301642243df483fd066d978317c113c04692b
ToppCellsaliva-Severe-critical_progression_d28-40-Epithelial-Epithelial,_Airway-secretory_cell|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TFPI2 TSPAN8 CHD6 MUC5AC AKR1C2

6.32e-06197595d6c9da7a3a6d2bcb13e2fc6605c8a59e7fb121c5
ToppCellsaliva-Severe-critical_progression_d28-40-Epithelial-Epithelial,_Airway-secretory_cell-Epi-Secretory|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TFPI2 TSPAN8 CHD6 MUC5AC AKR1C2

6.32e-0619759580b05c8ad9c1edc5dea3236079372475431343fe
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SFRP1 TRIM2 TSPAN8 LTBP2 RP1

6.32e-061975954ea3f57cd88b8a6bb7cb4b9e3545c0fa8f331886
ToppCellBL-critical-LOC-Epithelial-Secretory_LYPD2|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

TFPI2 TSPAN8 MUC5AC AKR1C1 AKR1C2

6.48e-06198595484d16aaa601a1e11b871b0475dd01a2de1a29ce
ToppCell(5)_Fibroblasts-(5)_Fibroblast-D|(5)_Fibroblasts / Lung cell shreds - cell class (v4) and cell subclass (v4)

SFRP1 SFRP2 ADAM15 AKR1C3 AKR1C1

6.48e-06198595fd14efd8e6c74a04bde985c08dc34217c0ef1bab
ToppCelldistal-mesenchymal-Adventitial_Fibroblast-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SFRP1 SFRP2 TSPAN8 LTBP2 SVEP1

6.48e-06198595bfd720e2dae3b6b3dc2bf8b2096c554fd456e756
ToppCellmoderate-Epithelial-Secretory|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

ADAM15 TSPAN8 MUC5AC AKR1C1 AKR1C2

6.48e-061985957d96d7105a849c7280ce87bd76ce130ac47384fd
ToppCellNS-critical-LOC-Epithelial-Secretory_LYPD2|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

TFPI2 TSPAN8 MUC5AC AKR1C1 AKR1C2

6.48e-061985954a481e1edb80b950c823ed926842cd5132cfb27f
ToppCellNS-moderate-d_07-13-Epithelial-Secretory-diff|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

TFPI2 TSPAN8 MUC5AC AKR1C1 AKR1C2

6.48e-06198595361f3062f73a0add16dd6fbe927698416515879f
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP251 TRIM2 DGKH RP1 MUC5AC

6.48e-06198595d0ecace1fad24ce50b0935036fabb07e6c9e372d
ToppCell367C-Fibroblasts-Fibroblast-E-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

SFRP1 SFRP2 AKR1C3 AKR1C1 SVEP1

6.64e-061995952aed8f4a225a3762a5e7ce99aacad9b2a37d61f1
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Perivascular_fibroblast|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SFRP2 LTBP2 AKR1C1 AKR1C2 SVEP1

6.64e-06199595dfc5c7a4a093baa7158dd8d4d29a870d9c469a3f
ToppCell368C-Fibroblasts-Fibroblast-D-|368C / Donor, Lineage, Cell class and subclass (all cells)

SFRP1 SFRP2 TSPAN8 AKR1C3 AKR1C1

6.64e-061995955a425e7d11c5911ff5855c27a7f058a7ed7abbb0
ToppCell367C-Fibroblasts-Fibroblast-E|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

SFRP1 SFRP2 AKR1C3 AKR1C1 SVEP1

6.64e-06199595c40ca26345753a2197bd9389d7323f7491c1e11d
ToppCell368C-Fibroblasts-Fibroblast-D|368C / Donor, Lineage, Cell class and subclass (all cells)

SFRP1 SFRP2 TSPAN8 AKR1C3 AKR1C1

6.64e-0619959566545eb7f65e450b742628fd431956e13330a0d3
ToppCelldistal-2-mesenchymal-Adventitial_Fibroblast|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SFRP1 SFRP2 TSPAN8 LTBP2 SVEP1

6.64e-0619959597b475f9110ef7bb29d9cf2109b7e43177830f05
ToppCelldistal-Epithelial-Mucous-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

TSPAN8 GLIS3 MUC5AC AKR1C1 AKR1C2

6.64e-061995950af89ef40807fc4ad79ab82a2186ab6e866c6931
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Perivascular_fibroblast-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SFRP2 LTBP2 AKR1C1 AKR1C2 SVEP1

6.64e-06199595c1760581c34b81d1d92c67500a1c8944e9cc6dad
ToppCell(5)_Fibroblast-D|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

SFRP1 SFRP2 SLIT1 TSPAN8 AKR1C1

6.64e-061995953f415620ad8b8d8c6871e1353e13f87b281fcc0e
ToppCellmoderate-Epithelial-Secretory-diff|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

TFPI2 TSPAN8 MUC5AC AKR1C1 AKR1C2

6.80e-062005956f29ef9dcf126c5c19386f6aa9a20c38a2c8ccc8
ToppCellNeuronal-Excitatory-eC(RORB)-eC_1-CARM1P1--L3-4|Neuronal / cells hierarchy compared to all cells using T-Statistic

TEX30 PIK3C2G GLIS3 DGKH CCDC168

6.80e-0620059547791c93d03ee17c1ce17e27f075be4fc6f2590e
ToppCellmoderate-Epithelial|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

TRIM2 AKR1C3 MUC5AC AKR1C1 AKR1C2

6.80e-06200595095783c9b75113ae350c2d5fb1195d71b41fa695
ToppCellNS-moderate-d_07-13-Epithelial|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

TRIM2 AKR1C3 MUC5AC AKR1C1 AKR1C2

6.80e-0620059585940b4bf7971b872469dea8b8d7a45bdeb2a909
ToppCell367C-Fibroblasts-Fibroblast-E-|367C / Donor, Lineage, Cell class and subclass (all cells)

SFRP1 SFRP2 TSPAN8 AKR1C1 SVEP1

6.80e-0620059557b9d6aa2265ab178a5886f36ecc66115bd382a8
ToppCellParenchymal-10x3prime_v2-Stromal-Fibroblastic-Fibro_adventitial|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

SFRP1 SFRP2 TSPAN8 AKR1C1 SVEP1

6.80e-06200595fc3c4778841c4b8bac0afb458352614b2c460617
ToppCellTransplant_Alveoli_and_parenchyma-Mesenchymal-Fibroblasts|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X

SFRP1 SFRP2 TSPAN8 LTBP2 SVEP1

6.80e-06200595bfa73bc5f8a6c7de8353ca049a921ef19f7f4437
ToppCellBiopsy_Other_PF-Mesenchymal-PLIN2+_Fibroblasts|Biopsy_Other_PF / Sample group, Lineage and Cell type

SFRP1 SFRP2 TFPI2 AKR1C1 SVEP1

6.80e-062005950aa316b71f195ecf17ee897e307f8928a755a637
ToppCellNeuronal-Excitatory-eC(RORB)-eC_1-CARM1P1|Neuronal / cells hierarchy compared to all cells using T-Statistic

TEX30 PIK3C2G GLIS3 DGKH CCDC168

6.80e-06200595f75d95376a340d467c4392b872b2a2dbdd184556
ToppCellParenchyma_Control_(B.)-Stromal-TX|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

SFRP1 SFRP2 TSPAN8 LTBP2 SVEP1

6.80e-062005950a86656d48e4238d0e4d592d477d29f7ba7c2ec0
ToppCellParenchyma_COVID-19-Epithelial-TX-Club|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

TRIM2 TSPAN8 MUC5AC AKR1C1 AKR1C2

6.80e-0620059585f946dd3831acf3488c87efba96689cc2667c3a
ToppCellNeuronal-Excitatory-eC(RORB)-eC_1-CARM1P1-|Neuronal / cells hierarchy compared to all cells using T-Statistic

TEX30 PIK3C2G GLIS3 DGKH CCDC168

6.80e-06200595fae26560ba3b0b638b6bcf92f05330824b31d21b
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

SFRP1 SFRP2 TSPAN8 LTBP2 SVEP1

6.80e-062005953fa7d9ea67f9cc55478d085da53babd03dbe9bb1
ToppCellParenchymal-10x5prime-Stromal-Fibroblastic-Fibro_adventitial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

SFRP1 SFRP2 TSPAN8 LTBP2 SVEP1

6.80e-062005956b48ddde83bc6c941d557844aa214d4d2c8e736d
ToppCellFibroblast|World / shred by cell class for parenchyma

SFRP2 SLIT1 LTBP2 ZEB2 SVEP1

6.80e-06200595dec9ce1bc2571197003596f32e5f742ede72aa79
ToppCellLung_Parenchyma-Control-Mesenchymal|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

SFRP1 SFRP2 TSPAN8 LTBP2 SVEP1

6.80e-062005951e75d1302c22e1b1666c19c0c9259d5cc8be16d5
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-Club-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TRIM2 TSPAN8 MUC5AC AKR1C1 AKR1C2

6.80e-062005958a44a4f7ea9358f2194a490e79601c98ff7fdcb0
ToppCell367C-Fibroblasts-Fibroblast-E|367C / Donor, Lineage, Cell class and subclass (all cells)

SFRP1 SFRP2 TSPAN8 AKR1C1 SVEP1

6.80e-06200595ddfbc004e7bd2fd3f11f046ed8fc049277160547
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-Club|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

TRIM2 TSPAN8 MUC5AC AKR1C1 AKR1C2

6.80e-0620059530d428510c68da96c7c8cfd472f449ebb9631132
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP6 SFRP1 PIK3C2G USH2A

3.58e-051405945e81fa3a19d23f0e9cae3878431ca1f78dff7238
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature3_(17)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

ARHGAP6 SFRP1 GLIS3 ZEB2

3.99e-051445941c001a5a3bbe4ecbce8305f8b260e933033550dd
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-proliferative_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CHST15 RXFP1 ZEB2 SVEP1

4.10e-05145594051d964ff6bdc12ba3f0459d3e6ab16fa9507b0b
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Degenerative_Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SFRP1 AMIGO3 ZNF425 CCDC168

4.10e-0514559407acbf086cffce0628accf078d31bf190f803988
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Mucinous_Lepidic_Adenocarcinoma-7|TCGA-Lung / Sample_Type by Project: Shred V9

PIK3C2G TSPAN8 PSAPL1 MUC5AC

4.81e-051515943dfa1d89975ffaa45b26833538244153d50c60a7
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Mucinous_Lepidic_Adenocarcinoma|TCGA-Lung / Sample_Type by Project: Shred V9

PIK3C2G TSPAN8 PSAPL1 MUC5AC

4.81e-0515159460bb6de5d9b13402bc18cb6d5e51078326dff8e2
ToppCell367C-Fibroblasts-Fibroblast-D-|367C / Donor, Lineage, Cell class and subclass (all cells)

SFRP1 SFRP2 AKR1C1 SVEP1

5.19e-05154594dd3d34f065820e706515a13619f19a5b12734c8e
ToppCell367C-Fibroblasts-Fibroblast-D|367C / Donor, Lineage, Cell class and subclass (all cells)

SFRP1 SFRP2 AKR1C1 SVEP1

5.19e-051545944bfda1c41efbb86d829b3797d1168bf2587c3c97
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP6 SFRP1 PIK3C2G LTBP2

6.02e-051605948bcdbcfdf1e0ace6053e8de82762f6e2f86bba7a
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP6 SFRP1 PIK3C2G LTBP2

6.02e-051605942d391ba6f7adb55dfa89feecc10cc9ce97e5fe74
ToppCell3'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TSPAN8 GLIS3 MUC5AC AKR1C1

6.63e-05164594c5bfae7e9497185548c243d6f9ebadbcef48ba7f
ToppCell3'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)-Goblet_(bronchial)_L.0.4.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TSPAN8 GLIS3 MUC5AC AKR1C1

6.63e-0516459476b0ac220b7ca22fbea28a507f01f96ae9f53932
ToppCell3'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TSPAN8 GLIS3 MUC5AC AKR1C1

6.63e-05164594911081739174ec68bc0893c804e4276b206bea7d
ComputationalDRG (dorsal root ganglia) genes.

SFRP1 TRIM2 CRIM1 TSPAN8 LTBP2 AKR1C1

8.23e-04384326MODULE_2
ComputationalCNS genes.

SFRP1 TRIM2 CHST15 SLIT1 TSPAN8 AKR1C1 AKR1C2

9.30e-04546327MODULE_137
ComputationalTrachea genes.

SFRP1 TRIM2 CRIM1 TSPAN8 AKR1C3 AKR1C1

1.23e-03415326MODULE_6
ComputationalGenes in the cancer module 311.

AKR1C1 AKR1C2

1.28e-0318322MODULE_311
ComputationalIntermediate filaments.

TFPI2 AKR1C3 AKR1C1

1.40e-0375323MODULE_154
ComputationalGenes in the cancer module 186.

LTBP2 AKR1C4

1.58e-0320322MODULE_186
ComputationalIntermediate filaments and keratins.

TFPI2 AKR1C3 AKR1C1

1.69e-0380323MODULE_357
ComputationalGenes in the cancer module 297.

TFPI2 AKR1C3 AKR1C1

1.69e-0380323MODULE_297
ComputationalGenes in the cancer module 71.

LTBP2 AKR1C4

1.91e-0322322MODULE_71
DrugPregnanes

AKR1C3 AKR1C4 AKR1C1 AKR1C2

3.79e-114584ctd:D011278
Drugtetralol

AKR1C3 AKR1C4 AKR1C1 AKR1C2

3.79e-114584ctd:C019106
Drug3',3'',5',5''-tetrabromophenolphthalein

AKR1C3 AKR1C4 AKR1C1 AKR1C2

3.79e-114584ctd:C018156
Drugcloxazolam

AKR1C3 AKR1C4 AKR1C1 AKR1C2

3.79e-114584ctd:C005522
DrugHydroxysteroids

AKR1C3 AKR1C4 AKR1C1 AKR1C2

1.89e-105584ctd:D006914
Drugcresolphthalein

AKR1C3 AKR1C4 AKR1C1 AKR1C2

1.89e-105584ctd:C010092
DrugMedazepam

AKR1C3 AKR1C4 AKR1C1 AKR1C2

5.66e-106584ctd:D008472
DrugNitrazepam

AKR1C3 AKR1C4 AKR1C1 AKR1C2

2.63e-098584ctd:D009567
Drug4-hydroxybenzoic acid

AKR1C3 AKR1C4 AKR1C1 AKR1C2

4.73e-099584ctd:C038193
Drug20-alpha-Dihydroprogesterone

AKR1C3 AKR1C4 AKR1C1 AKR1C2

4.73e-099584ctd:D004092
Drugoctyl gallate

AKR1C3 AKR1C4 AKR1C1 AKR1C2

7.87e-0910584ctd:C016627
DrugDihydroxydihydrobenzopyrenes

AKR1C3 AKR1C4 AKR1C1 AKR1C2

1.23e-0811584ctd:D004101
Drugchlordecone alcohol

AKR1C3 AKR1C4 AKR1C1 AKR1C2

1.23e-0811584CID000013946
Drugcyclopentanone

AKR1C3 AKR1C1 AKR1C2

1.57e-083583ctd:C007201
Drug5-dihydrodeoxycorticosterone

AKR1C4 AKR1C1 AKR1C2

1.57e-083583ctd:C454687
Drug4-benzoylbenzoic acid

AKR1C3 AKR1C1 AKR1C2

1.57e-083583ctd:C058818
Drugcyclopentanol

AKR1C3 AKR1C1 AKR1C2

1.57e-083583ctd:C016327
Drugdichloro(4-cymene)ruthenium(II)

AKR1C3 AKR1C1 AKR1C2

1.57e-083583ctd:C530610
DrugPhenolphthalein

AKR1C3 AKR1C4 AKR1C1 AKR1C2

1.85e-0812584ctd:D020113
DrugDMBA-3,4-dihydrodiol

AKR1C3 AKR1C4 AKR1C1 AKR1C2

2.66e-0813584CID000050096
Drugflunisolide

AKR1C3 AKR1C4 AKR1C1 AKR1C2

2.66e-0813584ctd:C007734
Drug1-acenaphthenol

AKR1C3 AKR1C4 AKR1C1 AKR1C2

3.72e-0814584CID000022750
Drug5-alpha-Dihydroprogesterone

AKR1C3 AKR1C4 AKR1C1 AKR1C2

3.72e-0814584ctd:D043582
DrugMeclofenamic Acid

AKR1C3 AKR1C4 AKR1C1 AKR1C2

3.72e-0814584ctd:D008469
Drugtetrahydrodeoxycorticosterone

AKR1C4 AKR1C1 AKR1C2

6.26e-084583ctd:C009413
Druggliquidone

AKR1C3 AKR1C1 AKR1C2

6.26e-084583ctd:C010969
DrugDBD-H

AKR1C3 AKR1C4 AKR1C1

6.26e-084583CID000131382
Drugoxcarbazepine

AKR1C3 AKR1C4 AKR1C1 AKR1C2

1.43e-0719584ctd:C036006
DrugNSC86000

AKR1C3 AKR1C1 AKR1C2

1.56e-075583CID000257630
Drugbenzo(a)pyrene-7,8-dione

AKR1C3 AKR1C4 AKR1C1 AKR1C2

1.78e-0720584ctd:C076588
DrugChrysenes

AKR1C3 AKR1C4 AKR1C1 AKR1C2

1.78e-0720584ctd:D002911
DrugFlunitrazepam

AKR1C3 AKR1C4 AKR1C1 AKR1C2

2.20e-0721584ctd:D005445
Drugbenzene dihydrodiol

AKR1C3 AKR1C4 AKR1C1 AKR1C2

2.68e-0722584CID000000418
DrugAC1L93E5

AKR1C3 AKR1C4 AKR1C1

3.12e-076583CID000412383
Drugacenaphthene-1-ol

AKR1C3 AKR1C1 AKR1C2

3.12e-076583ctd:C023723
DrugEstazolam

AKR1C3 AKR1C1 AKR1C2

3.12e-076583ctd:D004949
Drug3-hydroxyhexobarbital

AKR1C3 AKR1C4 AKR1C2

3.12e-076583CID000439898
DrugGlipizide

AKR1C3 AKR1C1 AKR1C2

3.12e-076583ctd:D005913
Drugphenolphthalein

AKR1C3 AKR1C4 AKR1C1 AKR1C2 B3GAT3

3.72e-0758585CID000004764
DrugGlycyrrhetinic Acid

AKR1C3 AKR1C4 AKR1C1 AKR1C2

3.88e-0724584ctd:D006034
DrugPregnanolone

AKR1C3 AKR1C4 AKR1C1 AKR1C2

4.61e-0725584ctd:D011280
Drug9,10-phenanthrenequinone

AKR1C3 AKR1C4 AKR1C1 AKR1C2

4.61e-0725584ctd:C005399
Drug4-hydroxyequilenin-o-quinone

AKR1C3 AKR1C1 AKR1C2

5.45e-077583ctd:C117714
Drugzomepirac

AKR1C3 AKR1C1 AKR1C2

5.45e-077583ctd:C020549
Drug2-cyclohexen-1-ol

AKR1C3 AKR1C4 AKR1C2

8.71e-078583CID000013198
Drugbenzo(a)pyrene 7,8-dihydrodiol

AKR1C3 AKR1C4 AKR1C1 AKR1C2

1.13e-0631584ctd:C017228
Drug20 alpha-dihydroprogesterone

AKR1C3 AKR1C4 AKR1C1 AKR1C2

3.24e-0640584CID000008956
Drugfenamic acid

AKR1C3 AKR1C1 AKR1C2

3.40e-0612583ctd:C001209
Drugo-quinone

AKR1C3 AKR1C4 AKR1C1 AKR1C2

3.58e-0641584CID000011421
Drugandrosterone glucuronide

AKR1C3 AKR1C1 AKR1C2 B3GAT3

4.34e-0643584CID000114833
Drug4-formyl-benzoate

AKR1C4 AKR1C1 AKR1C2

4.41e-0613583CID000012088
DrugFlufenamic Acid

AKR1C3 AKR1C4 AKR1C1 AKR1C2

5.22e-0645584ctd:D005439
Drugnaphthalene-1,2-dihydrodiol

AKR1C3 AKR1C4 AKR1C1 AKR1C2

5.22e-0645584CID000000362
DrugDydrogesterone

AKR1C3 AKR1C1 AKR1C2

5.60e-0614583ctd:D004394
Drug6-.beta.-Naltrexol

AKR1C4 AKR1C1 AKR1C2

5.60e-0614583CID000631219
Drug3-hydroxyandrostan-17-one

AKR1C3 AKR1C4 AKR1C1 AKR1C2 B3GAT3

6.20e-06102585CID000000225
Drugalpha-methylcinnamic acid

AKR1C3 AKR1C1

6.38e-062582ctd:C510582
Drug(10ALPHA,13ALPHA,14BETA,17ALPHA)-17-HYDROXYANDROST-4-EN-3-ONE

AKR1C1 AKR1C2

6.38e-062582DB07768
Drugbaccharin

AKR1C3 AKR1C2

6.38e-062582ctd:C012764
Drugdrospirenone

AKR1C4 AKR1C1 AKR1C2

6.98e-0615583ctd:C035144
Drug9-cis-retinal

AKR1C3 AKR1C4 AKR1C1

8.58e-0616583ctd:C031390
Drugandrostane-3,17-dione

AKR1C3 AKR1C4 AKR1C1 AKR1C2

8.66e-0651584CID000000443
Drugbenzo(a)pyrene-1,6-quinone

AKR1C3 AKR1C1 AKR1C2

1.04e-0517583ctd:C030233
DrugTimolol maleate salt [26921-17-5]; Down 200; 9.2uM; MCF7; HT_HG-U133A

TRIM2 ADAM15 SVEP1 TRIM3 TNFRSF11B NSD3

1.05e-051965865280_DN
DrugDebrisoquin sulfate [581-88-4]; Up 200; 9uM; MCF7; HT_HG-U133A

TRIM2 TFPI2 DYRK1B LTBP2 AKR1C4 TRIM3

1.15e-051995863207_UP
DrugHexestrol

AKR1C3 AKR1C4 AKR1C1 AKR1C2

1.17e-0555584ctd:D006589
Drugcloxazolam

AKR1C3 AKR1C1 AKR1C2

1.25e-0518583CID000002816
Drugbenzo(a)pyrene-3,6-quinone

AKR1C3 AKR1C1 AKR1C2

1.25e-0518583ctd:C018003
DrugRuthenium Compounds

AKR1C3 AKR1C1 AKR1C2

1.25e-0518583ctd:D017975
Drug1,2-dihydroxynaphthalene

AKR1C3 AKR1C4 AKR1C1 AKR1C2

1.35e-0557584CID000011318
DrugNSC36919

AKR1C3 AKR1C4 AKR1C1 AKR1C2

1.45e-0558584CID000235496
DrugAC1L8ZBW

AKR1C4 AKR1C1 AKR1C2

1.48e-0519583CID000435356
DrugIrganox 1010

NSD1 REST

1.91e-053582CID000064819
Drugconiferaldehyde

AKR1C3 AKR1C1 AKR1C2

2.02e-0521583ctd:C075384
DrugDutasteride

AKR1C3 AKR1C1 AKR1C2

2.02e-0521583ctd:D000068538
Drugchlordecone

AKR1C3 AKR1C4 AKR1C1 AKR1C2

2.58e-0567584CID000000299
Drug2'-Monophosphoadenosine 5'-Diphosphoribose

AKR1C3 AKR1C1 AKR1C2

2.68e-0523583DB03461
Drugmedazepam

AKR1C3 AKR1C1 AKR1C2

3.06e-0524583CID000004041
Drug5 beta-pregnane-3,20-dione

AKR1C3 AKR1C4 AKR1C1 AKR1C2

3.43e-0572584CID000092745
DrugDiazepam

AKR1C3 AKR1C4 AKR1C1 AKR1C2

3.82e-0574584ctd:D003975
Drugglycolithocholic acid

AKR1C3 AKR1C4 AKR1C2

3.91e-0526583CID000115245
DrugBudesonide

AKR1C3 AKR1C4 AKR1C1 AKR1C2

5.19e-0580584ctd:D019819
Drug1,10-phenanthroline

AKR1C3 AKR1C4 AKR1C1 AKR1C2

5.72e-0582584ctd:C025205
Drugfarnesal

AKR1C3 AKR1C2

6.35e-055582ctd:C084519
DrugHydrocortisone

AKR1C3 AKR1C4 MAP3K7 AKR1C1 AKR1C2

6.69e-05167585ctd:D006854
Drugestazolam

AKR1C3 AKR1C1 AKR1C2

9.69e-0535583CID000003261
Drugquercitrin

AKR1C4 AKR1C1 AKR1C2

1.06e-0436583CID005280459
Drugtrifluoperazine dihydrochloride; Up 200; 10uM; MCF7; HT_HG-U133A

TRIM2 TFPI2 UBOX5 MUC5AC TNFRSF11B

1.14e-041875856984_UP
Drug1 C2

AKR1C3 AKR1C4 AKR1C1 AKR1C2

1.24e-04100584CID005327152
DrugMefenamic Acid

AKR1C3 AKR1C1 AKR1C2

1.34e-0439583ctd:D008528
DrugSalicylic Acid

AKR1C3 AKR1C1 AKR1C2

1.34e-0439583ctd:D020156
DrugNadolol [42200-33-9]; Up 200; 13uM; MCF7; HT_HG-U133A

TRIM2 ADAM15 PIDD1 UBOX5 TNFRSF11B

1.36e-041945854139_UP
DrugNSC3260

SFRP1 ADAM15 AKR1C3 TERT TNFRSF11B

1.39e-04195585CID000220461
DrugBetahistine mesylate [54856-23-4]; Up 200; 17.2uM; MCF7; HT_HG-U133A

PIDD1 LTBP2 UBOX5 MUC5AC TRIM3

1.39e-041955852833_UP
DrugAmiprilose hydrochloride [60414-06-4]; Up 200; 11.8uM; PC3; HT_HG-U133A

ARHGAP6 SFRP1 ADAM15 TSPAN8 TNFRSF11B

1.42e-041965854000_UP
DrugSulfadoxine [2447-57-6]; Up 200; 12.8uM; MCF7; HT_HG-U133A

ZNF711 USP34 TRIM2 LTBP2 UBOX5

1.42e-041965857205_UP
DrugIsopropamide iodide [71-81-8]; Up 200; 8.4uM; MCF7; HT_HG-U133A

TRIM2 PIDD1 REST UBOX5 SVEP1

1.42e-041965853461_UP
DrugAdiphenine hydrochloride [50-42-0]; Up 200; 11.4uM; HL60; HT_HG-U133A

PIDD1 SLC25A44 UBOX5 ZEB2 TNFRSF11B

1.42e-041965851872_UP
DrugEpirizole [18694-40-1]; Up 200; 17uM; HL60; HT_HG-U133A

SLC25A44 REST UBOX5 NSD3 PUS7L

1.46e-041975851845_UP
DrugIoversol [87771-40-2]; Down 200; 5uM; HL60; HT_HG-U133A

CRIM1 SLC25A44 LTBP2 REST UBOX5

1.46e-041975853026_DN
DiseaseNeoplasms, Hormone-Dependent

AKR1C3 AKR1C1 AKR1C2

7.21e-093583C0027661
DiseaseAmbiguous Genitalia

AKR1C3 AKR1C1 AKR1C2

7.19e-085583C0266362
DiseasePseudohermaphroditism

AKR1C3 AKR1C1 AKR1C2

7.19e-085583C0033804
DiseaseHermaphroditism

AKR1C3 AKR1C1 AKR1C2

7.19e-085583C0019269
DiseaseIntersex Conditions

AKR1C3 AKR1C1 AKR1C2

7.19e-085583C2930618
DiseaseSex Differentiation Disorders

AKR1C3 AKR1C1 AKR1C2

7.19e-085583C2930619
DiseaseDisorders of Sex Development

AKR1C3 AKR1C1 AKR1C2

2.51e-077583C0036875
DiseaseMALE PSEUDOHERMAPHRODITISM: DEFICIENCY OF TESTICULAR 17,20-DESMOLASE

AKR1C4 AKR1C2

3.80e-062582C1839840
Disease46,XY SEX REVERSAL 8

AKR1C4 AKR1C2

3.80e-062582614279
Disease46,XY disorder of sex development due to testicular 17,20-desmolase deficiency

AKR1C4 AKR1C2

3.80e-062582cv:C1839840
Disease46,XY sex reversal 8 (is_implicated_in)

AKR1C4 AKR1C2

3.80e-062582DOID:0111773 (is_implicated_in)
DiseaseSotos syndrome 1 (implicated_via_orthology)

NSD1 NSD3

1.14e-053582DOID:0112103 (implicated_via_orthology)
Diseaseautosomal recessive limb-girdle muscular dystrophy (implicated_via_orthology)

TRIM2 TRIM3

1.14e-053582DOID:0110274 (implicated_via_orthology)
Diseaseautosomal recessive limb-girdle muscular dystrophy type 2H (implicated_via_orthology)

TRIM2 TRIM3

1.14e-053582DOID:0110282 (implicated_via_orthology)
DiseaseSushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 measurement

ADAM15 SVEP1

2.27e-054582EFO_0803113
DiseaseDegenerative polyarthritis

TRIM2 TFPI2 AKR1C1 AKR1C2

3.44e-0593584C0029408
DiseaseOsteoarthrosis Deformans

TRIM2 TFPI2 AKR1C1 AKR1C2

3.44e-0593584C0086743
DiseaseHydrophthalmos

GLIS3 LTBP2

3.78e-055582C0020302
Diseasecortolone glucuronide (1) measurement

AKR1C3 AKR1C2

5.67e-056582EFO_0800552
Diseaseeye morphology measurement

ADAM15 GLIS3 RP1 MAP3K7 TNFRSF11B

7.01e-05218585EFO_0007858
DiseaseCHARGE syndrome (implicated_via_orthology)

CHD8 CHD6

7.92e-057582DOID:0050834 (implicated_via_orthology)
Diseasediastolic blood pressure, self reported educational attainment

PIK3C2G SLIT1

1.06e-048582EFO_0004784, EFO_0006336
DiseaseFEV/FEC ratio

USP34 SFRP1 SFRP2 CRIM1 GLIS3 NSD1 DEFB135 LTBP2 REST ZEB2

1.27e-0412285810EFO_0004713
Diseasealkaline phosphatase measurement

USP34 TRIM2 ZNF689 DEFB135 LTBP2 AKR1C4 RP1 TNFRSF11B DNMT1

1.52e-041015589EFO_0004533
DiseaseNeoplastic Cell Transformation

AKR1C3 AKR1C1 AKR1C2 ZEB2

1.64e-04139584C0007621
Diseasepulmonary fibrosis

TERT MUC5AC

2.06e-0411582EFO_0009448
Diseasemicrophthalmia (implicated_via_orthology)

ARHGAP6 CRIM1

2.47e-0412582DOID:10629 (implicated_via_orthology)
DiseaseEndometrioma

AKR1C3 RXFP1 AKR1C1 AKR1C2

2.88e-04161584C0269102
DiseaseEndometriosis

AKR1C3 RXFP1 AKR1C1 AKR1C2

2.88e-04161584C0014175
Diseaseresponse to methotrexate

AKR1C1 AKR1C2

4.48e-0416582GO_0031427
Diseasehypertrophic cardiomyopathy (is_marker_for)

MAP3K7 DNMT1

5.07e-0417582DOID:11984 (is_marker_for)
Diseasesyndrome (implicated_via_orthology)

NSD1 NSD3

5.69e-0418582DOID:225 (implicated_via_orthology)
DiseaseMammary Carcinoma, Human

SFRP1 SFRP2 TFPI2 TERT ZEB2 DNMT1

5.70e-04525586C4704874
DiseaseMammary Neoplasms, Human

SFRP1 SFRP2 TFPI2 TERT ZEB2 DNMT1

5.70e-04525586C1257931
DiseaseMammary Neoplasms

SFRP1 SFRP2 TFPI2 TERT ZEB2 DNMT1

5.82e-04527586C1458155
Diseaseacute myeloid leukemia (is_implicated_in)

TFPI2 NSD1 TERT

6.13e-0484583DOID:9119 (is_implicated_in)
DiseaseBreast Carcinoma

SFRP1 SFRP2 TFPI2 TERT ZEB2 DNMT1

6.48e-04538586C0678222
Diseasebody weight

CLEC20A CRIM1 SLIT1 HDX TSPAN8 CHD8 DGKH LTBP2 MAP3K7

7.45e-041261589EFO_0004338
Diseasemuscular dystrophy (implicated_via_orthology)

TRIM2 TRIM3

7.78e-0421582DOID:9884 (implicated_via_orthology)
DiseaseInhalant adrenergic use measurement

TSPAN8 GLIS3 MUC5AC

9.04e-0496583EFO_0009941
Diseasecortical surface area measurement

USP34 SFRP1 SFRP2 TRIM2 ADAM15 GLIS3 REST MAP3K7 SVEP1

1.17e-031345589EFO_0010736
Diseasechronic myeloid leukemia (is_marker_for)

TERT DNMT1

1.29e-0327582DOID:8552 (is_marker_for)
Diseaseintelligence, response to cranial radiation therapy

SFRP2 TRIM2

1.39e-0328582EFO_0004337, EFO_0010950
Diseasepulse pressure measurement

USP34 CRIM1 SLIT1 DEFB135 LTBP2 SSPOP SVEP1 NSD3 DNMT1

1.49e-031392589EFO_0005763
DiseaseDrugs used in diabetes use measurement

TSPAN8 GLIS3 NSD1 LTBP2

1.60e-03255584EFO_0009924
Diseasebody surface area

CRIM1 SLIT1 NSD1 LTBP2 ZHX2 DNMT1

1.62e-03643586EFO_0022196

Protein segments in the cluster

PeptideGeneStartEntry
GLKYKPVCNQVECHP

AKR1C4

181

P17516
LYALVQLGQPCDCLP

B3GAT3

21

O94766
HLILCTGQQYQVPCP

CFAP61

766

Q8NHU2
LRKCCNHPYLINGAE

CHD8

1091

Q9HCK8
SKTHPPKCIQCGQYL

DNMT1

346

P26358
PKCIQCGQYLDDPDL

DNMT1

351

P26358
GLKYKPVCNQVECHP

AKR1C3

181

P42330
LHQRLCQLKGPTCQY

ADAM15

721

Q13444
LQLKYPHLPCLQVGQ

AGO1

316

Q9UL18
KNGLYLHNNPLPCDC

AMIGO3

211

Q86WK7
IHCDLKPENILLCNP

DYRK1B

236

Q9Y463
LNVAEQLCCYPGPVL

ABHD16B

301

Q9H3Z7
KDAICAISCHPYQPL

CFAP251

606

Q8TBY9
PGCPKVYHADCLNLT

NSD1

2136

Q96L73
VNTCHLPLNPALCIK

PIK3C2G

871

O75747
NGPKPLNCPHCDYKT

REST

356

Q13127
HNLCGQKPTIRDPYC

HDX

241

Q7Z353
HPNIVKLYGACLNPV

MAP3K7

86

O43318
GLICLNKNQLPPICY

MUC5AC

2021

P98088
KDLYHPICPLGQCKV

DGKH

291

Q86XP1
GCCHLKLPIPDQQLY

MTMR4

1146

Q9NYA4
LLIYLLPPCNCDTLH

ARHGAP6

506

O43182
LRKCCNHPYLINGAE

CHD6

741

Q8TD26
HLDTKPYACQIPGCT

GLIS3

466

Q8NEA6
IHLCCVNPKYLPILT

DEFB135

61

Q30KP9
AHLIKSCPGECYQLI

C1orf112

481

Q9NSG2
PIICDKYCPLGLLKN

CRIM1

541

Q9NZV1
LECPQGYKRLNLTHC

LTBP2

606

Q14767
ISCPQKYPCLLQHLM

CCDC168

3406

Q8NDH2
DLYPGGCQQLLHLCV

PIDD1

41

Q9HB75
SLDKLYALCGQHCPI

RP1

1906

P56715
GLHCDRCLPLYNDKP

USH2A

546

O75445
VCCNGVLYNPKPGHR

USH2A

3191

O75445
KEPVYQLPCGHLLCR

UBOX5

496

O94941
KPIPANLQLCHGIEY

SFRP2

41

Q96HF1
GCSILPLPYMIQCKH

PSAPL1

426

Q6NUJ1
LPRSQCPCQLHGQLY

SSPOP

2941

A2VEC9
NIPGCYRQILKHPCN

PUS7L

636

Q9H0K6
LSYLCPKECPHIVFQ

SLC25A44

211

Q96H78
LVLYLKNGADCPCHQ

SFRP1

246

Q8N474
NHLIPYCKAVSCGKP

SVEP1

1836

Q4LDE5
GLKYKPVCNQVECHP

AKR1C1

181

Q04828
GLKYKPVCNQVECHP

AKR1C2

181

P52895
RCLPHFYIIGQPKCG

CHST15

251

Q7LFX5
KPFLCYCDPDVGHLI

CLEC20A

126

Q6ZU45
SHQLLCDKCPPGTYL

TNFRSF11B

36

O00300
YFPCGNITKCLPQLL

RXFP1

31

Q9HBX9
GLICISYPLHHPKQQ

TEX30

126

Q5JUR7
CPKAYHLLCLNLTQP

NSD3

1341

Q9BZ95
HPNVILNPLYVCAEC

ZHX2

101

Q9Y6X8
LQHQLLHTGEKPYPC

ZNF689

361

Q96CS4
NNAEICLLPLDYGPC

TFPI2

31

P48307
PLHLLRYVCLFCGKN

USP34

206

Q70CQ2
CLERYKNPKVLPCLH

TRIM2

26

Q9C040
LRIHSGEKPYECPNC

ZEB2

301

O60315
DGQPLTVYPCHICTK

ZNF711

376

Q9Y462
PCRKLYCLHGICQPN

SLIT1

1341

O75093
LRLHSGEKPYQCPEC

ZNF425

601

Q6IV72
AQCPYGVLLKTHCPL

TERT

401

O14746
QHYPELCACLDKQRP

TSPAN8

166

P19075
LDRYQCPKVLPCLHT

TRIM3

26

O75382
DPCLLPEVCLLYNKG

ZC3HAV1L

161

Q96H79