Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyCellularComponenttranscription repressor complex

DDX20 SPEN

6.05e-048792GO:0017053
GeneOntologyCellularComponentendoplasmic reticulum protein-containing complex

PIGM DNAJC10

1.24e-0312592GO:0140534
PathwayREACTOME_SARS_COV_2_INFECTION

DDX20 ACE2

6.36e-0329962M41727
PathwayWP_MRNA_PROCESSING

DDX20 SPEN

1.41e-0245162MM15946
PathwayREACTOME_SARS_COV_INFECTIONS

DDX20 ACE2

1.53e-0247162M39009
Pubmed

FIP200 controls the TBK1 activation threshold at SQSTM1/p62-positive condensates.

DDX20 TOPORS DNAJC10

2.12e-052239334226595
Pubmed

The von Hippel-Lindau Cullin-RING E3 ubiquitin ligase regulates APOBEC3 cytidine deaminases.

HNRNPUL2 DNAJC10

4.62e-05409234004371
Pubmed

Comparative interactome analysis of α-arrestin families in human and Drosophila.

DDX20 SPEN DNAJC10

5.83e-053139338270169
Pubmed

Misregulation of Alternative Splicing in a Mouse Model of Rett Syndrome.

HNRNPUL2 GRIA2

6.96e-05499227352031
Pubmed

The variant Polycomb Repressor Complex 1 component PCGF1 interacts with a pluripotency sub-network that includes DPPA4, a regulator of embryogenesis.

DDX20 SPEN HNRNPUL2

1.17e-043969326687479
Pubmed

A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

DDX20 SPEN HNRNPUL2

2.37e-045039316964243
InteractionPFN2 interactions

DDX20 ACE2 GRIA2

3.91e-0515993int:PFN2
InteractionCRNKL1 interactions

SPEN HNRNPUL2 ACE2

5.38e-0517793int:CRNKL1
InteractionSAFB2 interactions

TOPORS HNRNPUL2 ACE2

7.18e-0519593int:SAFB2
InteractionRBBP4 interactions

TOPORS SPEN HNRNPUL2 ACE2

7.27e-0557394int:RBBP4
InteractionH2AX interactions

TOPORS HNRNPUL2 ACE2 GRIA2

8.31e-0559394int:H2AX
InteractionOASL interactions

DDX20 HNRNPUL2 DNAJC10

1.07e-0422393int:OASL
InteractionSTARD7 interactions

ACE2 PIGM

1.30e-043992int:STARD7
ToppCellfacs-Lung-24m-Hematologic-lymphocytic-mature_NK_T_cell-mature_NK_T_cell_l22|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SPEN GRIA2

4.79e-0416692bcdaab49bde5beba750b76fdcc3781a3c12c4fff
ToppCellfacs-Lung-24m-Hematologic-lymphocytic-mature_NK_T_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SPEN GRIA2

4.79e-04166925e3b998d740b24f790fad37350d704ca0ea10b77
ToppCell3'-Airway_Nasal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_mucus_secreting_cell-SMG_mucous-SMG_mucous_L.0.6.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GRIA2 DNAJC10

5.26e-0417492b1b54e4e23df8cfc04bf298d5c53de203a38b267
ToppCellfacs-Pancreas-Endocrine-24m-Epithelial-pancreatic_A_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACE2 GRIA2

5.38e-04176923027d34fd663c8a08544d469183dc45138916749
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_A_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACE2 GRIA2

5.44e-0417792426a9845df7fd13b02e744532c336c60bc4d4a22
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_A_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACE2 GRIA2

5.44e-04177921dc69c661e70e7e22bd9d7cf953eb638da9fd43c
ToppCelldroplet-Lung-30m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l2-17-52|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DDX20 DNAJC10

5.56e-0417992af03705a783e77f75c44fdfa793cfdccbf9dd91c
ToppCellPND03-Epithelial-Epithelial_Airway-Neurosecretory|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ACE2 GRIA2

5.69e-0418192092a971661b0aa06c1cdf428dbfa7339a26fb678
ToppCellfacs-Pancreas-Endocrine-3m-Epithelial-pancreatic_PP_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACE2 GRIA2

5.75e-0418292eb4be1c02b8b033d025e57b8b4cdbfaec4698054
ToppCellfacs-Pancreas-Endocrine-18m-Epithelial-pancreatic_A_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACE2 GRIA2

5.75e-0418292f5f42e23832d0210560009ce6fd8eee89751e252
ToppCelldroplet-Pancreas-Endocrine-18m-Epithelial-pancreatic_PP_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACE2 GRIA2

5.75e-04182925b2bad38c723cd64a7fe7f2dcd361708014c8cfe
ToppCell3'-Airway_Nasal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_mucus_secreting_cell-SMG_mucous-SMG_mucous_L.0.6.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GRIA2 DNAJC10

5.75e-04182926d7ba2e1f33aaa499a898ed9587197c0ee625e9a
ToppCelldroplet-Pancreas-Endocrine-18m-Epithelial-pancreatic_PP_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACE2 GRIA2

5.75e-0418292de90bf587a73973a8b1458c9cd366c274b72ef9e
ToppCell3'-Airway_Nasal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_mucus_secreting_cell-SMG_mucous|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GRIA2 DNAJC10

5.94e-0418592b931ab35da10e6e3877071dce9b13fc0da63dc88
ToppCelldroplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_A_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACE2 GRIA2

5.94e-04185924e40d3103ebf4a7066b7ce300b6ef700ba0e2863
ToppCell3'-Airway_Nasal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_mucus_secreting_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GRIA2 DNAJC10

5.94e-0418592d9039770226338fbc3fce92aa229fad96e16db8c
ToppCellfacs-Pancreas-Endocrine-3m-Epithelial-pancreatic_A_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACE2 GRIA2

6.00e-04186924bb54043f944a979db91bde9a86dd66f498c7658
ToppCelldroplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_A_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACE2 GRIA2

6.00e-041869216092819e9148dfe64f07c737652b6e533e699f7
ToppCellPCW_07-8.5-Epithelial-Epithelial_neuroendo-epi_neuroendocrine2[NE2]_(12)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

HABP2 GRIA2

6.00e-0418692c7983281a290201567b398e9ea6baddb96c692bb
ToppCell10x_3'_v2v3-Neoplastic-Stem-like-OPC-like-OPC-like-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TOPORS GRIA2

6.00e-041869210565fce7e1b4ec88bc8e1ed6410a83800be5014
ToppCellfacs-Pancreas-Endocrine-3m-Epithelial-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACE2 GRIA2

6.13e-0418892e99e3765b48392c987cf0c5ccbded0655637d7b7
ToppCelldroplet-Pancreas-Endocrine-18m-Epithelial-pancreatic_A_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACE2 GRIA2

6.20e-0418992ce3fbaf9642785c8adf6edaeae20998bca558928
ToppCelldroplet-Pancreas-Endocrine-18m-Epithelial-pancreatic_A_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACE2 GRIA2

6.26e-0419092db19c72d8c8053262b535068c5a9d4d696989cb1
ToppCellfacs-Pancreas-Endocrine-3m|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACE2 GRIA2

6.33e-0419192b3de0393d6510543533cd851e47a0f95739a0e4e
ToppCellfacs-Pancreas-Endocrine-3m-Epithelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACE2 GRIA2

6.33e-0419192657297cd19d05a7e7bb74fc3a086fbd95f47aae4
ToppCell3'-GW_trimst-1-SmallIntestine|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HABP2 ACE2

6.87e-0419992c4a1e0cf3be867e7cebbd8bd3668bc2df391671b
DrugBPPs

SPEN ACE2

1.66e-051692CID000004936
Drugtryptophanyl-5'AMP

SPEN ACE2

3.50e-052392CID000446202
Drugcetylpyridinium chloride

HABP2 SPEN

1.30e-044492CID000002683
Drugmagnesium fluoride

SPEN HNRNPUL2

1.89e-045392CID000024546
DrugCelecoxib

ACE2 GRIA2 DNAJC10

3.49e-0437693ctd:D000068579
Drugmethylformamide

HABP2 TOPORS

6.87e-0410192ctd:C002950
Drug6,7-dimethoxy-2-(pyrrolidin-1-yl)-N-(5-(pyrrolidin-1-yl)pentyl)quinazolin-4-amine

SPEN GRIA2

7.29e-0410492ctd:C000595015
DiseaseSeizures, Focal

GRIA2 PIGM

3.40e-0410482C0751495
DiseaseMyoclonic Seizures

GRIA2 PIGM

3.40e-0410482C4317123
DiseaseTonic - clonic seizures

GRIA2 PIGM

3.40e-0410482C0494475
DiseaseSpontaneous abortion

HABP2 ACE2

3.73e-0410982C0000786
DiseaseAbortion, Tubal

HABP2 ACE2

3.73e-0410982C0000822
DiseaseEarly Pregnancy Loss

HABP2 ACE2

3.73e-0410982C3830362
DiseaseMiscarriage

HABP2 ACE2

3.73e-0410982C4552766
DiseaseSeizures

GRIA2 PIGM

1.48e-0321882C0036572
DiseaseIntellectual Disability

ACE2 GRIA2

6.04e-0344782C3714756
DiseaseProstatic Neoplasms

SPEN DNAJC10

1.12e-0261682C0033578
DiseaseMalignant neoplasm of prostate

SPEN DNAJC10

1.12e-0261682C0376358

Protein segments in the cluster

PeptideGeneStartEntry
FSDTYQDYEEYWRAY

DDX20

766

Q9UHI6
YWRAYYRAWQEYYAA

DDX20

776

Q9UHI6
EYYQWDKFAYLYDSD

GRIA2

141

P42262
YRDYYRQYNRDWQSY

HNRNPUL2

711

Q1KMD3
DWTPDQYDYSYEDYN

HABP2

36

Q14520
YEDYGDYWRGDYEVN

ACE2

196

Q9BYF1
QYESWNYYRYDFGIY

DNAJC10

111

Q8IXB1
EFYSEWETYQGDYYE

SPEN

656

Q96T58
WETYQGDYYESRYYD

SPEN

661

Q96T58
YGSRYKWEYTYYSRN

TOPORS

696

Q9NS56
YYEYGWEFLEHTYFY

PIGM

246

Q9H3S5