Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	DUF1220	NBPF4 NBPF6	1.02e-04	9	32	2	SM01148
Domain	NBPF	NBPF4 NBPF6	1.55e-04	11	32	2	PS51316
Domain	DUF1220	NBPF4 NBPF6	1.55e-04	11	32	2	PF06758
Domain	NBPF_dom	NBPF4 NBPF6	1.55e-04	11	32	2	IPR010630
Domain	IBR	CUL9 ARIH2	2.55e-04	14	32	2	PF01485
Domain	IBR	CUL9 ARIH2	2.55e-04	14	32	2	SM00647
Domain	IBR_dom	CUL9 ARIH2	2.94e-04	15	32	2	IPR002867
Domain	MYB_LIKE	GON4L NCOR1	1.92e-03	38	32	2	PS50090
Domain	SANT	GON4L NCOR1	3.31e-03	50	32	2	SM00717
Domain	SANT/Myb	GON4L NCOR1	3.57e-03	52	32	2	IPR001005
Domain	-	TFDP3 CUL9 FOXR2	6.06e-03	218	32	3	1.10.10.10
Domain	WHTH_DNA-bd_dom	TFDP3 CUL9 FOXR2	8.08e-03	242	32	3	IPR011991
Pubmed	Alterations in the balance of tubulin glycylation and glutamylation in photoreceptors leads to retinal degeneration.	TTLL3 AGTPBP1	8.73e-07	2	33	2	28104815
Pubmed	A novel gene family NBPF: intricate structure generated by gene duplications during primate evolution.	NBPF4 NBPF6 NBPF5P	1.02e-06	21	33	3	16079250
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	CUL9 NCOR1 SRPK2 PPP6R1 ANKHD1 FOXR2 AGTPBP1 RBM26	1.06e-06	857	33	8	25609649
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	GON4L SRPK2 PPP6R1 CLSPN ANKHD1 RIC1 PLCE1	2.16e-06	650	33	7	38777146
Pubmed	Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	NCOR1 PPP6R1 ANKHD1 AGTPBP1	2.89e-06	104	33	4	10470851
Pubmed	The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells.	CUL9 NCOR1 TNRC18 PPP6R1 LAS1L	6.67e-06	282	33	5	23667531
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	CUL9 NCOR1 TNRC18 PPP6R1 SRCAP ANKHD1 RIC1 ZNF316	6.93e-06	1105	33	8	35748872
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	CUL9 SRPK2 PPP6R1 CLSPN SRCAP ANKHD1 AGTPBP1 ZNF316	7.45e-06	1116	33	8	31753913
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	GON4L CUL9 PPP6R1 AGTPBP1 PLCE1	3.88e-05	407	33	5	12693553
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	EHBP1 TFDP3 NCOR1 PPP6R1 ANKHD1	4.40e-05	418	33	5	34709266
Pubmed	A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.	EHBP1 PPP6R1 LAS1L CLSPN SLC7A6OS AGTPBP1 RBM26	4.48e-05	1038	33	7	26673895
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	KCNMA1 EHBP1 SRPK2 BTF3L4 TNRC18 TTLL3 SEPTIN5 RIC1	5.90e-05	1489	33	8	28611215
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	GON4L SRPK2 BTF3L4 MPHOSPH10 LAS1L ANKHD1 SEPTIN5 RBM26	6.13e-05	1497	33	8	31527615
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	GON4L NCOR1 TNNT1 AGTPBP1 PLCE1	9.96e-05	497	33	5	23414517
Pubmed	A novel nuclear receptor corepressor complex, N-CoR, contains components of the mammalian SWI/SNF complex and the corepressor KAP-1.	NCOR1 SRCAP	1.04e-04	16	33	2	11013263
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	CUL9 NCOR1 PPP6R1 CLSPN SRCAP	2.18e-04	588	33	5	38580884
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	EHBP1 BTF3L4 PPP6R1 SRCAP ANKHD1 RBM26	2.20e-04	934	33	6	33916271
Pubmed	Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.	NCOR1 LAS1L SRCAP RBM26	2.97e-04	341	33	4	32971831
Pubmed	Human transcription factor protein interaction networks.	GON4L CUL9 NCOR1 PPP6R1 LAS1L SRCAP ANKHD1	3.25e-04	1429	33	7	35140242
Pubmed	Genomic analysis of mouse retinal development.	TFDP3 CUL9 NCOR1 SRPK2 BTF3L4 SEPTIN5	3.27e-04	1006	33	6	15226823
Pubmed	Gene expression in the developing mouse retina by EST sequencing and microarray analysis.	SRPK2 ANKHD1 AGTPBP1	3.32e-04	142	33	3	11812828
Pubmed	Centronuclear myopathy in mice lacking a novel muscle-specific protein kinase transcriptionally regulated by MEF2.	SRPK2 TNNT1	3.99e-04	31	33	2	16140986
Pubmed	Myotubularin-related proteins 3 and 4 interact with polo-like kinase 1 and centrosomal protein of 55 kDa to ensure proper abscission.	PPP6R1 CLSPN AGTPBP1	5.34e-04	167	33	3	25659891
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	NCOR1 TNRC18 CLSPN RIC1	7.10e-04	430	33	4	35044719
Pubmed	FBXL13 directs the proteolysis of CEP192 to regulate centrosome homeostasis and cell migration.	PPP6R1 AGTPBP1	7.34e-04	42	33	2	29348145
Pubmed	Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.	SRPK2 MPHOSPH10 LAS1L SRCAP	7.73e-04	440	33	4	34244565
Pubmed	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.	SRPK2 MPHOSPH10 LAS1L ANKHD1 RBM26	9.20e-04	807	33	5	22681889
Cytoband	1p13.3	NBPF4 NBPF6 NBPF5P	1.72e-05	69	33	3	1p13.3
Cytoband	Ensembl 112 genes in cytogenetic band chr1p13	NBPF4 NBPF6 NBPF5P	4.72e-04	211	33	3	chr1p13
Cytoband	7p22.1	TNRC18 ZNF316	5.31e-04	47	33	2	7p22.1
Cytoband	Ensembl 112 genes in cytogenetic band chr7p22	TNRC18 ZNF316	4.21e-03	134	33	2	chr7p22
GeneFamily	Neuroblastoma breakpoint family	NBPF4 NBPF6 NBPF5P	4.06e-06	23	25	3	662
GeneFamily	Armadillo repeat containing\|Protein phosphatase 1 regulatory subunits	NCOR1 MPHOSPH10 RBM26	1.93e-03	181	25	3	694
GeneFamily	GATA zinc finger domain containing\|Myb/SANT domain containing	GON4L NCOR1	2.42e-03	53	25	2	532
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_2500_k-means-cluster#5	GON4L NCOR1 SRPK2 MPHOSPH10 CLSPN ANKHD1 ANKRD40 AGTPBP1	2.42e-05	831	32	8	Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_2500_K5
Drug	Chlormezanone [80-77-3]; Down 200; 14.6uM; MCF7; HT_HG-U133A	TFDP3 GON4L CUL9 SRCAP ANKRD40	7.68e-06	197	32	5	3235_DN
Disease	developmental disorder of mental health (implicated_via_orthology)	NCOR1 SRCAP	1.30e-03	49	32	2	DOID:0060037 (implicated_via_orthology)
Disease	gastric carcinoma	GON4L PLCE1	4.21e-03	89	32	2	EFO_0000178
Disease	Glioblastoma Multiforme	NCOR1 SRPK2	6.46e-03	111	32	2	C1621958
Disease	lean body mass	KCNMA1 ZNF777 PLCE1	7.91e-03	379	32	3	EFO_0004995

Protein segments in the cluster

Peptide	Gene	Start	Entry
DSNEEDYDPNCEEEE	ARIH2	11	O95376
DYDPNCEEEEEEEED	ARIH2	16	O95376
EEEDDDDDDDDNLPQ	ANKRD40	96	Q6AI12
PEVDDVVDESDDNDD	AGTPBP1	361	Q9UPW5
KLSPENDEDEDEDED	NBPF4	161	Q96M43
DDSLLQDDDEEEEDN	RBM26	986	Q5T8P6
EEDTAQAEEEEPFQD	RIC1	1401	Q4ADV7
VQFLDQDDDDDPDTE	KCNMA1	1011	Q12791
NPDAQDDQAEEEEED	MARCHF6	221	O60337
DNDEEEEDIDFFEDI	MPHOSPH10	226	O00566
PDQVEEEEENDDQEE	LAS1L	576	Q9Y4W2
DEEDDDVPDLVENFD	BTF3L4	136	Q96K17
EDDSSDEEYQPDDEE	GON4L	366	Q3T8J9
DEEYQPDDEEEDETA	GON4L	371	Q3T8J9
EEEDFDDLTQDEEDE	GON4L	1461	Q3T8J9
LDDFEEDNEDDDENR	EHBP1	186	Q8NDI1
DFELTEEEAEEPDDN	FOXR2	151	Q6PJQ5
EEDDEDDVPEWQQDE	CUL9	2466	Q8IWT3
EEDNDDIENILEDEF	AK9	1226	Q5TCS8
EQEYEEEQPEEEAAE	TNNT1	6	P13805
PECDSDEDEDFKQQD	SEPTIN5	221	Q99719
KLSPENDEDEDEDED	NBPF5P	161	Q86XG9
KLSPENDEDEDEDED	NBPF6	161	Q5VWK0
PANNEEEEDEEDEYD	PLCE1	1576	Q9P212
DEDIEASNEEENPED	NCOR1	711	O75376
DGDFQPQEDEEEDDE	SRCAP	286	Q6ZRS2
PDEDDEEFTANEEEA	SRCAP	396	Q6ZRS2
EEFTANEEEAEDEED	SRCAP	401	Q6ZRS2
ENSELPEDEDEEEND	ANKHD1	1481	Q8IWZ3
PEDEDEEENDEDVEQ	ANKHD1	1486	Q8IWZ3
EEEEEEEGNQETAEF	CLSPN	666	Q9HAW4
QEPEDIYDDEDDENS	SLC7A6OS	231	Q96CW6
FDQDESSEEEDEEEE	TNRC18	1821	O15417
PFSLEQQLDDEDDDE	SRPK2	391	P78362
EDEDEDEDEEFQPSQ	TTLL3	71	Q9Y4R7
EEEEEEDNNDDDLSE	TFDP3	386	Q5H9I0
RIQQFDDDEEEEDEE	PPP6R1	616	Q9UPN7
DDEDFLAEVAEEENE	ZNF316	251	A6NFI3
QDEEEEEEEEDELPQ	ZNF777	456	Q9ULD5