Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionG protein-coupled glutamate receptor binding

HOMER3 HOMER2 HOMER1

5.41e-0516943GO:0035256
GeneOntologyBiologicalProcessG protein-coupled glutamate receptor signaling pathway

GRM8 HOMER3 HOMER2 HOMER1

7.06e-0716944GO:0007216
GeneOntologyBiologicalProcesscalcium ion transport

CACNA2D1 CLCA1 PDGFRB PMPCB TRPC6 FGF2 DMD MCUB HOMER3 HOMER2 HOMER1

2.02e-055099411GO:0006816
GeneOntologyCellularComponentpostsynaptic density

MAP1B ASIC2 PKP4 SORCS2 SORCS3 EEF2K DMD HOMER3 HOMER2 HOMER1

3.55e-054519410GO:0014069
GeneOntologyCellularComponentasymmetric synapse

MAP1B ASIC2 PKP4 SORCS2 SORCS3 EEF2K DMD HOMER3 HOMER2 HOMER1

5.68e-054779410GO:0032279
GeneOntologyCellularComponentapical part of cell

ACE2 CLCA4 CLIC5 PDGFRB TJP1 PTPRQ PLET1 TEK ENPEP HOMER2 HOMER1

7.05e-055929411GO:0045177
GeneOntologyCellularComponentglutamatergic synapse

CACNA2D1 MAP1B IL1RAPL2 NXPH1 NGEF SORCS3 EEF2K PARN ARHGAP39 GRM8 HOMER3 HOMER2 HOMER1

7.30e-058179413GO:0098978
GeneOntologyCellularComponentpostsynaptic specialization

MAP1B ASIC2 PKP4 SORCS2 SORCS3 EEF2K DMD HOMER3 HOMER2 HOMER1

8.82e-055039410GO:0099572
GeneOntologyCellularComponentneuron to neuron synapse

MAP1B ASIC2 PKP4 SORCS2 SORCS3 EEF2K DMD HOMER3 HOMER2 HOMER1

1.21e-045239410GO:0098984
GeneOntologyCellularComponentpostsynapse

CACNA2D1 MAP1B ASIC2 PKP4 NGEF SORCS2 SORCS3 EEF2K PARN ARHGAP39 DMD HOMER3 HOMER2 HOMER1

1.77e-0410189414GO:0098794
GeneOntologyCellularComponentapical plasma membrane

ACE2 CLCA4 CLIC5 PDGFRB TJP1 PTPRQ PLET1 TEK ENPEP

3.46e-04487949GO:0016324
GeneOntologyCellularComponentstereocilium base

CLIC5 PTPRQ

5.50e-048942GO:0120044
GeneOntologyCellularComponentneuronal cell body

MAP1B ASIC2 LNPEP XRN1 SORCS2 INPP5F DMD ENDOG GRM8 HOMER2 HOMER1

1.30e-038359411GO:0043025
GeneOntologyCellularComponentactin-based cell projection

CLCA1 CLIC5 PTPRQ DMD TEK HOMER2

1.61e-03278946GO:0098858
DomainWH1

HOMER3 HOMER2 HOMER1

1.79e-0511913SM00461
DomainWH1/EVH1_dom

HOMER3 HOMER2 HOMER1

1.79e-0511913IPR000697
DomainWH1

HOMER3 HOMER2 HOMER1

1.79e-0511913PF00568
DomainWH1

HOMER3 HOMER2 HOMER1

3.09e-0513913PS50229
DomainCLCA_chordata

CLCA4 CLCA1

7.02e-053912IPR004727
DomainCLCA

CLCA4 CLCA1

7.02e-053912PF08434
DomainCLCA

CLCA4 CLCA1

7.02e-053912IPR013642
DomainNxph

NXPH1 NXPH3

1.40e-044912IPR010450
DomainVPS10

SORCS2 SORCS3

2.33e-045912SM00602
DomainSortilin_C

SORCS2 SORCS3

2.33e-045912PF15901
DomainSortilin-Vps10

SORCS2 SORCS3

2.33e-045912PF15902
DomainVPS10

SORCS2 SORCS3

2.33e-045912IPR006581
DomainSortilin_N

SORCS2 SORCS3

2.33e-045912IPR031778
DomainSortilin_C

SORCS2 SORCS3

2.33e-045912IPR031777
DomainPKD

SORCS2 SORCS3

4.85e-047912PF00801
DomainERAP1-like_C_dom

LNPEP ENPEP

6.45e-048912IPR024571
DomainNXPH/NXPE

NXPH1 NXPH3

6.45e-048912IPR026845
DomainERAP1_C

LNPEP ENPEP

6.45e-048912PF11838
DomainNeurexophilin

NXPH1 NXPH3

6.45e-048912PF06312
DomainSialidases

SORCS2 SORCS3

8.27e-049912IPR011040
DomainPKD

SORCS2 SORCS3

1.25e-0311912PS50093
DomainPKD_dom

SORCS2 SORCS3

1.25e-0311912IPR000601
Domain-

SORCS2 SORCS3

1.25e-03119122.60.40.670
DomainPeptidase_M1

LNPEP ENPEP

1.50e-0312912IPR001930
DomainWW

WWC2 ARHGAP39 DMD

1.55e-0347913PF00397
DomainWW

WWC2 ARHGAP39 DMD

1.65e-0348913SM00456
DomainPeptidase_M1

LNPEP ENPEP

1.77e-0313912PF01433
DomainPeptidase_M1_N

LNPEP ENPEP

1.77e-0313912IPR014782
DomainWW_DOMAIN_2

WWC2 ARHGAP39 DMD

1.97e-0351913PS50020
DomainWW_DOMAIN_1

WWC2 ARHGAP39 DMD

1.97e-0351913PS01159
DomainWW_dom

WWC2 ARHGAP39 DMD

2.08e-0352913IPR001202
DomainVWA

CACNA2D1 CLCA4 CLCA1

2.57e-0356913PF00092
DomainPCI_dom

PSMD13 PCID2

3.04e-0317912IPR000717
DomainPCI

PSMD13 PCID2

3.04e-0317912PF01399
DomainFGF

FGF2 FGF3

5.09e-0322912SM00442
DomainFGF

FGF2 FGF3

5.09e-0322912PF00167
DomainHBGF_FGF

FGF2 FGF3

5.09e-0322912PS00247
DomainFibroblast_GF_fam

FGF2 FGF3

5.09e-0322912IPR002209
DomainIL-1_fam/FGF_fam

FGF2 FGF3

5.56e-0323912IPR028142
Domain-

CACNA2D1 CLCA4 CLCA1

5.65e-03749133.40.50.410
Pubmed

Differential expression of Homer family proteins in the developing mouse brain.

HOMER3 HOMER2 HOMER1

1.97e-08395315116392
Pubmed

Homer is concentrated at the postsynaptic density and does not redistribute after acute synaptic stimulation.

HOMER3 HOMER2 HOMER1

1.97e-08395324530450
Pubmed

Homer proteins regulate sensitivity to cocaine.

HOMER3 HOMER2 HOMER1

1.97e-08395315294147
Pubmed

Distinct and Overlapping Expression Patterns of the Homer Family of Scaffolding Proteins and Their Encoding Genes in Developing Murine Cephalic Tissues.

HOMER3 HOMER2 HOMER1

1.97e-08395332070057
Pubmed

Mutation screening of the Homer gene family and association analysis in schizophrenia.

HOMER3 HOMER2 HOMER1

1.97e-08395312815733
Pubmed

Homer 2 tunes G protein-coupled receptors stimulus intensity by regulating RGS proteins and PLCbeta GAP activities.

HOMER3 HOMER2 HOMER1

7.88e-08495312860966
Pubmed

Homer regulates gain of ryanodine receptor type 1 channel complex.

HOMER3 HOMER2 HOMER1

7.88e-08495312223488
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

TUBB6 KIF18A WWC2 PTPRJ PMPCB TJP1 LNPEP CTR9 PKP4 PSMD13 NUP93 ARHGAP39 DMD GOLGA4 NSD3

1.64e-071049951527880917
Pubmed

Large-scale structural analysis of the classical human protein tyrosine phosphatome.

PTPRJ PDGFRB PPP1R12A PKP4 TEK

1.91e-074795519167335
Pubmed

Homer1a regulates Shank3 expression and underlies behavioral vulnerability to stress in a model of Phelan-McDermid syndrome.

HOMER3 HOMER2 HOMER1

1.97e-07595334788607
Pubmed

Preso1 dynamically regulates group I metabotropic glutamate receptors.

HOMER3 HOMER2 HOMER1

1.97e-07595322561452
Pubmed

Comparative interactome analysis of α-arrestin families in human and Drosophila.

CACNA2D1 GTF3C1 MAP1B PMPCB U2SURP BTBD10 PSMD13 INPP5F DMD

2.06e-0731395938270169
Pubmed

Homer binds a novel proline-rich motif and links group 1 metabotropic glutamate receptors with IP3 receptors.

HOMER3 HOMER2 HOMER1

3.93e-0769539808459
Pubmed

A prolyl-isomerase mediates dopamine-dependent plasticity and cocaine motor sensitization.

HOMER3 HOMER2 HOMER1

3.93e-07695323911326
Pubmed

Homer regulates the association of group 1 metabotropic glutamate receptors with multivalent complexes of homer-related, synaptic proteins.

HOMER3 HOMER2 HOMER1

6.86e-0779539808458
Pubmed

NFAT binding and regulation of T cell activation by the cytoplasmic scaffolding Homer proteins.

HOMER3 HOMER2 HOMER1

6.86e-07795318218901
Pubmed

Homer binds TRPC family channels and is required for gating of TRPC1 by IP3 receptors.

TRPC6 HOMER3 HOMER1

1.64e-06995314505576
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

ERGIC1 TUBB6 ELOC LNPEP CTR9 ACKR3 PPP1R12A PKP4 XRN1 PARN ARHGAP39 SEC63 HOMER3 IQGAP3 PCID2 NSD3

2.85e-061497951631527615
Pubmed

Cupidin, an isoform of Homer/Vesl, interacts with the actin cytoskeleton and activated rho family small GTPases and is expressed in developing mouse cerebellar granule cells.

HOMER3 HOMER2 HOMER1

3.21e-061195310493740
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

ERGIC1 KIF18A CACNA2D1 NR2C2 GTF3C1 MAP1B PTPRJ LNPEP ACKR3 SEC63 DNAJC3 B4GALT5 KRTCAP2 TMED3

4.79e-061201951435696571
Pubmed

Angiopoietin-1 Is Required for Vortex Vein and Choriocapillaris Development in Mice.

PDGFRB TJP1 TEK

7.03e-061495336172864
Pubmed

The int-2 gene product acts as a growth factor and substitutes for basic fibroblast growth factor in promoting the differentiation of a normal mouse mammary epithelial cell line.

FGF2 FGF3

7.38e-0629521376141
Pubmed

Neurexophilin 3 is highly localized in cortical and cerebellar regions and is functionally important for sensorimotor gating and motor coordination.

NXPH1 NXPH3

7.38e-06295216055736
Pubmed

No association of alcohol dependence with HOMER 1 and 2 genetic variants.

HOMER2 HOMER1

7.38e-06295220333726
Pubmed

Homer2 and Homer3 modulate RANKL-induced NFATc1 signaling in osteoclastogenesis and bone metabolism.

HOMER3 HOMER2

7.38e-06295231319381
Pubmed

ACE2 and AT4R are present in diseased human blood vessels.

ACE2 LNPEP

7.38e-06295218502721
Pubmed

Localization and expression of group I metabotropic glutamate receptors in the mouse striatum, globus pallidus, and subthalamic nucleus: regulatory effects of MPTP treatment and constitutive Homer deletion.

HOMER2 HOMER1

7.38e-06295217553998
Pubmed

Reciprocal Homer1a and Homer2 Isoform Expression Is a Key Mechanism for Muscle Soleus Atrophy in Spaceflown Mice.

HOMER2 HOMER1

7.38e-06295235008503
Pubmed

The CLCA gene locus as a modulator of the gastrointestinal basic defect in cystic fibrosis.

CLCA4 CLCA1

7.38e-06295215490240
Pubmed

Behavioral and neurochemical phenotyping of Homer1 mutant mice: possible relevance to schizophrenia.

HOMER2 HOMER1

7.38e-06295216011574
Pubmed

Diagnostic Potential of Differentially Expressed Homer1 and Homer2 in Ischemic Stroke.

HOMER2 HOMER1

7.38e-06295227832625
Pubmed

Molecular characterisation of two structurally distinct groups of human homers, generated by extensive alternative splicing.

HOMER3 HOMER2

7.38e-06295210653696
Pubmed

Imbalances in prefrontal cortex CC-Homer1 versus CC-Homer2 expression promote cocaine preference.

HOMER2 HOMER1

7.38e-06295223658151
Pubmed

Site-selective dephosphorylation of the platelet-derived growth factor beta-receptor by the receptor-like protein-tyrosine phosphatase DEP-1.

PTPRJ PDGFRB

7.38e-06295210821867
Pubmed

ACE2 is augmented in dystrophic skeletal muscle and plays a role in decreasing associated fibrosis.

ACE2 DMD

7.38e-06295224695436
Pubmed

Primary sequence determinants responsible for site-selective dephosphorylation of the PDGF beta-receptor by the receptor-like protein tyrosine phosphatase DEP-1.

PTPRJ PDGFRB

7.38e-06295212062403
Pubmed

Expression and regulation of Homer in human skeletal muscle during neuromuscular junction adaptation to disuse and exercise.

HOMER2 HOMER1

7.38e-06295221885651
Pubmed

Novel role of aminopeptidase-A in angiotensin-(1-7) metabolism post myocardial infarction.

ACE2 ENPEP

7.38e-06295224464749
Pubmed

Association of a polymorphism in the Homer1 gene with cocaine dependence in an African American population.

HOMER2 HOMER1

7.38e-06295216314758
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

TUBB6 ACE2 PGS1 GTF3C1 MAP1B CTR9 PKP4 XRN1 PARN IQGAP3

1.18e-05650951038777146
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

TUBB6 CACNA2D1 TJP1 PPP1R12A PKP4 NGEF PARN ARHGAP39 HOMER3 HOMER2 HOMER1 GOLGA4

1.26e-05963951228671696
Pubmed

A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.

WWC2 GTF3C1 PMPCB TJP1 LNPEP CTR9 XRN1 PSMD13 NUP93 DMD SEC63 DNAJC3

1.41e-05974951228675297
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

TUBB6 GTF3C1 MAP1B PMPCB CTR9 PKP4 U2SURP CGAS XRN1 PSMD13 NUP93 GOLGA4 PCID2 CCDC93

1.83e-051353951429467282
Pubmed

Tie2-mediated loss of peroxisome proliferator-activated receptor-gamma in mice causes PDGF receptor-beta-dependent pulmonary arterial muscularization.

PDGFRB TEK

2.21e-05395219801450
Pubmed

Expression analysis of the CLCA gene family in mouse and human with emphasis on the nervous system.

CLCA4 CLCA1

2.21e-05395219210762
Pubmed

PI3 kinase enhancer-Homer complex couples mGluRI to PI3 kinase, preventing neuronal apoptosis.

HOMER2 HOMER1

2.21e-05395214528310
Pubmed

Colocalization of bFGF and the myogenic regulatory gene myogenin in dystrophic mdx muscle precursors and young myotubes in vivo.

FGF2 DMD

2.21e-0539527781901
Pubmed

Transient receptor potential channel 6 regulates abnormal cardiac S-nitrosylation in Duchenne muscular dystrophy.

TRPC6 DMD

2.21e-05395229187535
Pubmed

The three sorCS genes are differentially expressed and regulated by synaptic activity.

SORCS2 SORCS3

2.21e-05395215009648
Pubmed

Identification of three novel members of the calcium-dependent chloride channel (CaCC) family predominantly expressed in the digestive tract and trachea.

CLCA4 CLCA1

2.21e-05395210437792
Pubmed

VEGFR2 signaling drives meningeal vascular regeneration upon head injury.

PDGFRB TEK

2.21e-05395232737287
Pubmed

Homer2 and Homer3 interact with amyloid precursor protein and inhibit Abeta production.

HOMER3 HOMER2

2.21e-05395218387811
Pubmed

Hidden Twins: SorCS Neuroreceptors Form Stable Dimers.

SORCS2 SORCS3

2.21e-05395228827148
Pubmed

Genetic segregation of airway disease traits despite redundancy of calcium-activated chloride channel family members.

CLCA4 CLCA1

2.21e-05395216569774
Pubmed

Pharmacological TRPC6 inhibition improves survival and muscle function in mice with Duchenne muscular dystrophy.

TRPC6 DMD

2.21e-05395236099033
Pubmed

Spatiotemporal expression analysis of the growth factor receptor SorCS3.

SORCS2 SORCS3

2.21e-05395224715575
Pubmed

Endothelial cells regulated by RNF20 orchestrate the proliferation and differentiation of neural precursor cells during embryonic development.

PDGFRB TJP1 TEK

3.36e-052395336103829
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

TUBB6 GTF3C1 PMPCB TJP1 PPP1R12A PKP4 BTBD10 CGAS PSMD13 NUP93 SEC63 IQGAP3 NSD3

3.77e-051257951336526897
Pubmed

Stabilization of VEGFR2 signaling by cerebral cavernous malformation 3 is critical for vascular development.

PDGFRB TJP1 TEK

3.83e-052495320371769
Pubmed

Local expression of AP/AngIV/IRAP and effect of AngIV on glucose-induced epithelial transport in human jejunal mucosa.

LNPEP ENPEP

4.41e-05495226311161
Pubmed

Altered blood-brain barrier development in dystrophic MDX mice.

TJP1 DMD

4.41e-05495215120852
Pubmed

The genes for the human VPS10 domain-containing receptors are large and contain many small exons.

SORCS2 SORCS3

4.41e-05495211499680
Pubmed

STAT1 activation by venous malformations mutant Tie2-R849W antagonizes VEGF-A-mediated angiogenic response partly via reduced bFGF production.

FGF2 TEK

4.41e-05495223086340
Pubmed

High-throughput transcriptomic and RNAi analysis identifies AIM1, ERGIC1, TMED3 and TPX2 as potential drug targets in prostate cancer.

ERGIC1 TMED3

4.41e-05495222761906
Pubmed

MCU-independent Ca2+ uptake mediates mitochondrial Ca2+ overload and necrotic cell death in a mouse model of Duchenne muscular dystrophy.

DMD MCUB

4.41e-05495238514795
Pubmed

Severe alterations of endothelial and glial cells in the blood-brain barrier of dystrophic mdx mice.

TJP1 DMD

4.41e-05495212673830
Pubmed

Gene trap expression and mutational analysis for genes involved in the development of the mammalian nervous system.

MAP1B RTTN

4.41e-0549529626495
Pubmed

Polymorphisms in TGFB1 and PDGFRB are associated with Moyamoya disease in European patients.

PDGFRB FGF2

4.41e-05495220571834
Pubmed

The intracellular domain of the human protocadherin hFat1 interacts with Homer signalling scaffolding proteins.

HOMER3 HOMER1

4.41e-05495216979624
Pubmed

Molecular characteristics and functional diversity of CLCA family members.

CLCA4 CLCA1

4.41e-05495211071307
Pubmed

Critical role of TPRN rings in the stereocilia for hearing.

CLIC5 PTPRQ

4.41e-05495237952086
Pubmed

Biochemical and enzymatic properties of the M1 family of aminopeptidases involved in the regulation of blood pressure.

LNPEP ENPEP

4.41e-05495217999179
Pubmed

Aminopeptidase A is a functional target in angiogenic blood vessels.

FGF2 ENPEP

4.41e-05495214998491
Pubmed

Elongin A regulates transcription in vivo through enhanced RNA polymerase processivity.

ELOC CTR9 U2SURP

4.90e-052695333298525
Pubmed

Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.

ERGIC1 CACNA2D1 TJP1 LNPEP PPP1R12A U2SURP FGF2 PARN PSMD13 SEC63 DNAJC3 PCID2 NSD3

5.19e-051297951333545068
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

ERGIC1 SMPDL3B GTF3C1 MAP1B PTPRJ TJP1 ACKR3 PPP1R12A NGEF ARHGAP39 DNAJC3 DNAH14 GOLGA4 TTC19

5.20e-051489951428611215
Pubmed

A comprehensive SARS-CoV-2-human protein-protein interactome reveals COVID-19 pathobiology and potential host therapeutic targets.

ACE2 ELOC TJP1 CTR9 PPP1R12A NUP93 SEC63 DNAJC3

7.32e-0550395836217030
Pubmed

Density-enhanced phosphatase 1 regulates phosphorylation of tight junction proteins and enhances barrier function of epithelial cells.

PTPRJ TJP1

7.34e-05595219332538
Pubmed

Cell-based receptor discovery identifies host factors specifically targeted by the SARS CoV-2 spike.

ACE2 IL1RAPL2

7.34e-05595235931765
Pubmed

Hyperactive adverse mechanical stress responses in dystrophic heart are coupled to transient receptor potential canonical 6 and blocked by cGMP-protein kinase G modulation.

TRPC6 DMD

7.34e-05595224449818
Pubmed

Reduced mobility of fibroblast growth factor (FGF)-deficient myoblasts might contribute to dystrophic changes in the musculature of FGF2/FGF6/mdx triple-mutant mice.

FGF2 DMD

7.34e-05595212917328
Pubmed

PDGFRα signalling promotes fibrogenic responses in collagen-producing cells in Duchenne muscular dystrophy.

PDGFRB DMD

7.34e-05595227569721
Pubmed

Neurexophilins form a conserved family of neuropeptide-like glycoproteins.

NXPH1 NXPH3

7.34e-0559529570794
Pubmed

Expression and function of the SDF-1 chemokine receptors CXCR4 and CXCR7 during mouse limb muscle development and regeneration.

ACKR3 DMD

7.34e-05595222766125
Pubmed

Structure and evolution of neurexophilin.

NXPH1 NXPH3

7.34e-0559528699246
Pubmed

Negative regulation of Ros receptor tyrosine kinase signaling. An epithelial function of the SH2 domain protein tyrosine phosphatase SHP-1.

PDGFRB ROS1

7.34e-05595211266449
Pubmed

TRIP12 promotes small-molecule-induced degradation through K29/K48-branched ubiquitin chains.

ELOC CTR9 NSD3

1.01e-043395333567268
Pubmed

FGF signaling in mouse gastrulation and anteroposterior patterning.

FGF2 FGF3

1.10e-0469529598344
Pubmed

Identification of six novel autophosphorylation sites on fibroblast growth factor receptor 1 and elucidation of their importance in receptor activation and signal transduction.

FGF2 FGF3

1.10e-0469528622701
Pubmed

Localization of two metabotropic glutamate receptor genes, GRM3 and GRM8, to human chromosome 7q.

GRM8 DNAJC3

1.10e-0469528824806
Pubmed

Homer: a protein that selectively binds metabotropic glutamate receptors.

HOMER3 HOMER1

1.10e-0469529069287
Pubmed

Agonist-independent activation of metabotropic glutamate receptors by the intracellular protein Homer.

HOMER3 HOMER1

1.10e-04695211418862
Pubmed

Piezo2 expression and its alteration by mechanical forces in mouse mesangial cells and renin-producing cells.

PDGFRB TEK

1.10e-04695235273307
Pubmed

CLIC5 stabilizes membrane-actin filament linkages at the base of hair cell stereocilia in a molecular complex with radixin, taperin, and myosin VI.

CLIC5 PTPRQ

1.10e-04695224285636
Pubmed

HIV-host interactome revealed directly from infected cells.

ERGIC1 ELOC MAP1B PSMD13 DNAJC3

1.13e-0417295527375898
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

CACNA2D1 MAP1B TJP1 PPP1R12A PKP4 NGEF XRN1 SORCS2 ARHGAP39 DMD HOMER3 HOMER1 SCAI

1.39e-041431951337142655
Pubmed

Epicardial-myocardial signaling directing coronary vasculogenesis.

PDGFRB FGF2 TEK

1.43e-043795320299672
Pubmed

The CRL5-SPSB3 ubiquitin ligase targets nuclear cGAS for degradation.

ELOC CGAS

1.54e-04795238418882
Pubmed

Inhibition of telomerase RNA decay rescues telomerase deficiency caused by dyskerin or PARN defects.

XRN1 PARN

1.54e-04795226950371
Pubmed

Co-chaperone Specificity in Gating of the Polypeptide Conducting Channel in the Membrane of the Human Endoplasmic Reticulum.

SEC63 DNAJC3

1.54e-04795226085089
InteractionRYR1 interactions

CACNA2D1 RNF123 HOMER3 HOMER2 HOMER1

1.49e-0643925int:RYR1
InteractionHYOU1 interactions

ERGIC1 ACE2 CACNA2D1 NR2C2 PDGFRB LNPEP ROS1 TEK DNAJC3

1.46e-05317929int:HYOU1
GeneFamilyHomer scaffolding proteins

HOMER3 HOMER2 HOMER1

3.65e-083613871
GeneFamilyChloride channel accessory

CLCA4 CLCA1

6.69e-054612867
GeneFamilyFibronectin type III domain containing

IL31RA PTPRJ PTPRQ ROS1 TEK

2.03e-04160615555
GeneFamilyReceptor Tyrosine Kinases|CD molecules

PDGFRB ROS1 TEK

3.30e-0440613321
GeneFamilyAminopeptidases|CD molecules

LNPEP ENPEP

1.47e-0317612104
GeneFamilyProtein tyrosine phosphatases, receptor type

PTPRJ PTPRQ

2.26e-0321612813
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN

MAP1B PPP1R12A PKP4 U2SURP FGF2 PARN INPP5F HOMER1 GOLGA4 CCDC93

7.52e-064669510M13522
CoexpressionAtlasdev gonad_e12.5_M_InterstitTestis_Sma_k-means-cluster#4_top-relative-expression-ranked_1000

TUBB6 ACE2 CACNA2D1 CLCA1 PDGFRB SORCS2 SORCS3 ENPEP

1.96e-06191938gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_k4_1000
CoexpressionAtlasdev gonad_e13.5_M_InterstitTestis_Sma_k-means-cluster#1_top-relative-expression-ranked_500

ACE2 CACNA2D1 CLCA1 PDGFRB TRPC6 SORCS3 ENPEP

5.63e-06156937gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_k1_500
CoexpressionAtlasdev gonad_e13.5_M_InterstitFLeydig_MafB_k-means-cluster#4_top-relative-expression-ranked_100

ACE2 CLCA1 PDGFRB ENPEP

2.04e-0537934gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_k4_100
CoexpressionAtlaskidney_adult_RenMedVasc_Tie2_k-means-cluster#3_top-relative-expression-ranked_1000

CLIC5 TJP1 LNPEP DNAJC3 ENPEP

2.68e-0580935gudmap_kidney_adult_RenMedVasc_Tie2_k3_1000
CoexpressionAtlasdev gonad_e13.5_M_InterstitFLeydig_MafB_k-means-cluster#3_top-relative-expression-ranked_200

ACE2 CACNA2D1 CLCA1 PDGFRB ENPEP

3.02e-0582935gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_k3_200
CoexpressionAtlasDevelopingKidney_e15.5_Ureteral Smooth Musc_emap-28812_k-means-cluster#4_top-relative-expression-ranked_100

KIF18A CACNA2D1 PPP1R12A

5.29e-0517933gudmap_developingKidney_e15.5_Ureteral Smooth Musc_100_k4
CoexpressionAtlasDevelopingKidney_e15.5_Peripheral blastema_emap-27731_top-relative-expression-ranked_1000

DENND5B ACE2 ELOC KIF18A CACNA2D1 WWC2 ASIC2 LNPEP CGAS SEC63 ABCD2 NSD3 SCAI

5.71e-058199313gudmap_developingKidney_e15.5_Peripheral blastema_1000
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_top-relative-expression-ranked_2500_k-means-cluster#4

SPATA7 GTF3C1 MAP1B PPP1R12A PKP4 DHX32 INPP5F UBE2Q2 GOLGA4 TTC19 BCO1

5.81e-055959311Facebase_RNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_2500_K4
CoexpressionAtlasMyeloid Cells, Mo.6C-IIint.Bl, CD115+ B220- CD43- Ly6C- MHCIIint, Blood, avg-5

TUBB6 IL31RA SMPDL3B PTPRJ ARHGAP39 INPP5F ABCD2 MCUB B4GALT5

6.51e-05400939GSM605886_500
CoexpressionAtlasdev gonad_e13.5_M_InterstitFLeydig_MafB_k-means-cluster#3_top-relative-expression-ranked_1000

ACE2 CACNA2D1 CLCA1 PDGFRB TRPC6 SORCS2 SORCS3 ENPEP

1.15e-04336938gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_k3_1000
CoexpressionAtlaskidney_P0_CapMes_Crym_k-means-cluster#4_top-relative-expression-ranked_1000

DENND5B CACNA2D1 PTPRJ ACKR3

1.22e-0458934gudmap_kidney_P0_CapMes_Crym_k4_1000
CoexpressionAtlasdev gonad_e12.5_M_InterstitLeydig_MafB_k-means-cluster#2_top-relative-expression-ranked_200

ACE2 CLCA1 PDGFRB ENPEP

1.31e-0459934gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_k2_200
CoexpressionAtlaskidney_adult_JuxtaGlom_Ren1_Captopr_k-means-cluster#4_top-relative-expression-ranked_1000

CACNA2D1 PDGFRB TRPC6 DMD ENPEP NSD3

1.37e-04179936gudmap_kidney_adult_JuxtaGlom_Ren1_Captopr_k4_1000
CoexpressionAtlasFacebaseRNAseq_e10.5_Olfactory Pit_top-relative-expression-ranked_2500_k-means-cluster#2

DENND5B NR2C2 CLIC5 MAP1B ACKR3 SS18L1 SORCS3 DHX32 DMD HOMER2 SCAI

1.43e-046599311Facebase_RNAseq_e10.5_Olfactory Pit_2500_K2
CoexpressionAtlaskidney_P3_CapMes_Crym_k-means-cluster#2_top-relative-expression-ranked_1000

DENND5B CACNA2D1 PTPRJ ACKR3 ENPEP

1.46e-04114935gudmap_kidney_P3_CapMes_Crym_k2_1000
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_top-relative-expression-ranked_1000_k-means-cluster#3

SPATA7 PGS1 GTF3C1 PPP1R12A PKP4 BCO1

1.64e-04185936Facebase_RNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_1000_K3
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k-means-cluster#5_top-relative-expression-ranked_100

CACNA2D1 MAP1B LNPEP

1.97e-0426933DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k5_100
CoexpressionAtlasDevelopingKidney_e15.5_Pelvic Mesenchyme_emap-8241_top-relative-expression-ranked_1000

TUBB6 ACE2 KIF18A CACNA2D1 CLIC5 PMPCB PPP1R12A CGAS DNAJC3 TGM5 TTC19 STAB1

2.12e-048099312gudmap_developingKidney_e15.5_Pelvic Mesenchyme_1000
CoexpressionAtlasdev gonad_e13.5_M_InterstitTestis_Sma_k-means-cluster#1_top-relative-expression-ranked_100

ACE2 CLCA1 PDGFRB

2.20e-0427933gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_k1_100
CoexpressionAtlaskidney_P3_CapMes_Crym_top-relative-expression-ranked_500

DENND5B CACNA2D1 PTPRJ ACKR3 PLET1 BBS12 ENPEP HOMER2

2.21e-04370938gudmap_kidney_P3_CapMes_Crym_500
CoexpressionAtlaskidney_e15.5_Podocyte_MafB_top-relative-expression-ranked_1000

DENND5B ACE2 CACNA2D1 CLIC5 PTPRJ ACKR3 PLET1 ROS1 TEK BBS12 ENPEP HOMER2

2.24e-048149312gudmap_kidney_e15.5_Podocyte_MafB_1000
CoexpressionAtlaskidney_e15.5_Podocyte_MafB_k-means-cluster#2_top-relative-expression-ranked_500

CLIC5 PTPRJ ACKR3 ENPEP

2.40e-0469934gudmap_kidney_e15.5_Podocyte_MafB_k2_500
CoexpressionAtlaskidney_P2_CapMes_Crym_k-means-cluster#4_top-relative-expression-ranked_500

DENND5B CACNA2D1 PTPRJ

2.46e-0428933gudmap_kidney_P2_CapMes_Crym_k4_500
CoexpressionAtlasdev gonad_e12.5_M_InterstitTestis_Sma_k-means-cluster#2_top-relative-expression-ranked_500

CACNA2D1 CLCA1 PDGFRB SORCS3 ENPEP

2.69e-04130935gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_k2_500
CoexpressionAtlasDevelopingKidney_e15.5_Ureteral Smooth Musc_emap-28812_k-means-cluster#5_top-relative-expression-ranked_1000

CACNA2D1 LNPEP PPP1R12A SORCS3 DNAJC3 SCAI

2.71e-04203936gudmap_developingKidney_e15.5_Ureteral Smooth Musc_1000_k5
CoexpressionAtlasdev gonad_e13.5_M_InterstitFLeydig_MafB_top-relative-expression-ranked_100

ACE2 CLCA1 PDGFRB ENPEP

2.98e-0473934gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_100
CoexpressionAtlasFacebaseRNAseq_e9.5_Facial Mesenchyne_top-relative-expression-ranked_2500_k-means-cluster#5

DENND5B NR2C2 RNF123 CLIC5 ACKR3 SS18L1 SORCS3 DMD HOMER2 CCDC136 SCAI

3.15e-047229311Facebase_RNAseq_e9.5_Facial Mesenchyne_2500_K5
CoexpressionAtlasFacebaseRNAseq_e8.5_Paraxial Mesoderm_top-relative-expression-ranked_2500_k-means-cluster#3

DENND5B NR2C2 RNF123 CLIC5 ACKR3 SS18L1 SORCS3 DMD HOMER2 CCDC136 SCAI

3.46e-047309311Facebase_RNAseq_e8.5_Paraxial Mesoderm_2500_K3
CoexpressionAtlasdev gonad_e13.5_M_InterstitTestis_Sma_top-relative-expression-ranked_100

ACE2 CLCA1 PDGFRB ENPEP

3.48e-0476934gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_100
CoexpressionAtlasMyeloid Cells, Mo.6C-II-.Bl, CD115+ B220- CD43- Ly6C- MHCII-, Blood, avg-3

TUBB6 IL31RA SMPDL3B PTPRJ ARHGAP39 INPP5F ABCD2 B4GALT5

3.86e-04402938GSM605883_500
CoexpressionAtlasFacebaseRNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_2500_k-means-cluster#5

DENND5B NR2C2 RNF123 CLIC5 ACKR3 SS18L1 SORCS3 DMD HOMER2 CCDC136 SCAI

4.01e-047439311Facebase_RNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_2500_K5
CoexpressionAtlasDevelopingKidney_e15.5_Peripheral blastema_emap-27731_k-means-cluster#5_top-relative-expression-ranked_1000

KIF18A CACNA2D1 LNPEP SCAI

4.03e-0479934gudmap_developingKidney_e15.5_Peripheral blastema_1000_k5
CoexpressionAtlasdev gonad_e12.5_M_InterstitLeydig_MafB_k-means-cluster#1_top-relative-expression-ranked_1000

ACE2 CACNA2D1 CLCA1 PDGFRB TRPC6 SORCS2 ENPEP

4.28e-04310937gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_k1_1000
CoexpressionAtlasFacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_2500_k-means-cluster#5

SPATA7 CACNA2D1 PGS1 CLIC5 GTF3C1 PPP1R12A PKP4 DMD HOMER2 UBE2Q2

4.30e-046299310Facebase_RNAseq_e10.5_Maxillary Arch_2500_K5
CoexpressionAtlaskidney_e15.5_Podocyte_MafB_top-relative-expression-ranked_500

DENND5B ACE2 CACNA2D1 CLIC5 PTPRJ ACKR3 ROS1 ENPEP

4.54e-04412938gudmap_kidney_e15.5_Podocyte_MafB_500
CoexpressionAtlasdev gonad_e13.5_M_InterstitFLeydig_MafB_top-relative-expression-ranked_200

ACE2 CACNA2D1 CLCA1 PDGFRB ENPEP

4.59e-04146935gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_200
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_2500_k-means-cluster#3

DENND5B NR2C2 CLIC5 MAP1B TJP1 ACKR3 SS18L1 SORCS3 DHX32 DMD HOMER2 CCDC136

5.16e-048939312Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_2500_K3
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k-means-cluster#1_top-relative-expression-ranked_100

CACNA2D1 MAP1B LNPEP

5.23e-0436933DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k1_100
CoexpressionAtlasDevelopingKidney_e15.5_Ureteral Smooth Musc_emap-28812_top-relative-expression-ranked_100

KIF18A CACNA2D1 MAP1B PPP1R12A

5.32e-0485934gudmap_developingKidney_e15.5_Ureteral Smooth Musc_100
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_500_k-means-cluster#5

CACNA2D1 CLIC5 MAP1B DHX32 DMD HOMER2

5.51e-04232936Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_500_K5
CoexpressionAtlasDevelopingKidney_e15.5_Ureteral Smooth Musc_emap-28812_top-relative-expression-ranked_1000

TUBB6 KIF18A CACNA2D1 MAP1B LNPEP PPP1R12A RTTN CGAS SORCS3 DNAJC3 SCAI

5.53e-047729311gudmap_developingKidney_e15.5_Ureteral Smooth Musc_1000
CoexpressionAtlasdev gonad_e11.5_F_GonadVasMes_Flk_k-means-cluster#1_top-relative-expression-ranked_200

ACE2 CLCA1 PDGFRB

5.67e-0437933gudmap_dev gonad_e11.5_F_GonadVasMes_Flk_k1_200
CoexpressionAtlasDevelopingLowerUrinaryTract_P2_bladder stroma (LCM)_emap-30396_top-relative-expression-ranked_1000

TUBB6 CLCA1 CLIC5 CGAS PLET1 SORCS3 TEK MCUB ENDOG ENPEP TMED3

6.21e-047839311gudmap_developingLowerUrinaryTract_P2_bladder stroma (LCM)_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_top-relative-expression-ranked_100

CACNA2D1 CLCA1 MAP1B LNPEP

6.34e-0489934DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_100
CoexpressionAtlasDevelopingKidney_e14.5 whole kidney - wildtype_emap-6674_k-means-cluster#4_top-relative-expression-ranked_100

CLIC5 ENPEP

6.70e-049932gudmap_developingKidney_e14.5 whole kidney - wildtype_100_k4
CoexpressionAtlaskidney_adult_RenMedVasc_Tie2_k-means-cluster#2_top-relative-expression-ranked_200

CLIC5 ENPEP

6.70e-049932gudmap_kidney_adult_RenMedVasc_Tie2_k2_200
CoexpressionAtlasStromal Cells, LEC.MLN, gp38+ CD31+, Lymph Node, avg-4

CLCA1 TJP1 TEK STAB1

6.89e-0491934GSM777059_100
CoexpressionAtlaskidney_adult_RenalCortexMixed_Std_k-means-cluster#4_top-relative-expression-ranked_1000

CLIC5 PTPRJ ENPEP

7.15e-0440933gudmap_kidney_adult_RenalCortexMixed_Std_k4_1000
CoexpressionAtlasDevelopingKidney_e15.5_Ureteral Smooth Musc_emap-28812_k-means-cluster#4_top-relative-expression-ranked_200

KIF18A CACNA2D1 PPP1R12A

7.15e-0440933gudmap_developingKidney_e15.5_Ureteral Smooth Musc_200_k4
CoexpressionAtlasDevelopingKidney_e15.5_Ureteral Smooth Musc_emap-28812_top-relative-expression-ranked_200

TUBB6 KIF18A CACNA2D1 MAP1B PPP1R12A

7.77e-04164935gudmap_developingKidney_e15.5_Ureteral Smooth Musc_200
CoexpressionAtlasdev gonad_e12.5_M_InterstitLeydig_MafB_k-means-cluster#2_top-relative-expression-ranked_500

ACE2 CACNA2D1 CLCA1 PDGFRB ENPEP

7.99e-04165935gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_k2_500
CoexpressionAtlasStromal Cells, LEC.SLN, gp38+ CD31+, Lymph Node, avg-4

CLCA1 TJP1 TEK STAB1

8.42e-0496934GSM777063_100
CoexpressionAtlasdev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_k-means-cluster#4_top-relative-expression-ranked_1000

ACE2 CLCA1 PDGFRB TRPC6 ABCD2

8.66e-04168935gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_k4_1000
CoexpressionAtlasDevelopingKidney_e15.5_Medullary collecting duct_emap-28063_k-means-cluster#4_top-relative-expression-ranked_1000

PMPCB LNPEP PPP1R12A DNAJC3 GOLGA4 TTC19

1.02e-03261936gudmap_developingKidney_e15.5_Medullary collecting duct_1000_k4
CoexpressionAtlasdev gonad_e13.5_M_InterstitTestis_Sma_top-relative-expression-ranked_500

ACE2 CACNA2D1 CLCA1 PDGFRB TRPC6 SORCS3 ENPEP

1.05e-03361937gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_500
CoexpressionAtlasDevelopingKidney_e15.5_stage III -IV renal corpusc_emap-27945_top-relative-expression-ranked_1000

ACE2 CACNA2D1 WWC2 CLIC5 PMPCB ACKR3 INPP5F DNAJC3 ENPEP TTC19 STAB1

1.07e-038379311gudmap_developingKidney_e15.5_stage III -IV renal corpusc_1000
CoexpressionAtlasdev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k-means-cluster#2_top-relative-expression-ranked_1000

ACE2 CACNA2D1 CLCA1 PDGFRB TRPC6 SCAI

1.10e-03265936gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k2_1000
CoexpressionAtlasdev gonad_e11.5_F_PrimGermCell_Oct_k-means-cluster#2_top-relative-expression-ranked_1000

SPO11 NUP93 TEX15 SETD3

1.13e-03104934gudmap_dev gonad_e11.5_F_PrimGermCell_Oct_k2_1000
CoexpressionAtlasFacebaseRNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_top-relative-expression-ranked_2500_k-means-cluster#4

DENND5B NR2C2 RNF123 ACKR3 SS18L1 SORCS3 DMD HOMER2 CCDC136 SCAI

1.22e-037219310Facebase_RNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_2500_K4
CoexpressionAtlasdev gonad_e13.5_M_InterstitFLeydig_MafB_k-means-cluster#4_top-relative-expression-ranked_500

ACE2 CACNA2D1 CLCA1 PDGFRB ENPEP

1.24e-03182935gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_k4_500
ToppCellCOVID-19-kidney-Podocyte|kidney / Disease (COVID-19 only), tissue and cell type

SERPINI2 CLIC5 MAP1B PDGFRB TJP1 TRPC6 PTPRQ ENPEP

5.77e-09183958fb5e2a31b560126e1c04a386c24c365901c60ad7
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SERPINI2 CLIC5 PDGFRB TRPC6 PTPRQ TEX15 ENPEP

8.79e-081729576c17a1e586a72d1bd80c20c06370429c61dc9f85
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SERPINI2 CLIC5 PDGFRB TJP1 TRPC6 PTPRQ ENPEP

1.34e-071839573c516fe5083f02bad1f464ed284010b4131a833c
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SERPINI2 CLIC5 PDGFRB TJP1 TRPC6 PTPRQ ENPEP

1.34e-07183957612d93df03252d4d2ccdce5a9bc162cfd9172a1a
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SERPINI2 CLIC5 PDGFRB TJP1 TRPC6 PTPRQ ENPEP

1.34e-071839579c2689d76fc6d30f5ab093428aa669d0a98953cf
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SERPINI2 CLIC5 PDGFRB TJP1 TRPC6 PTPRQ ENPEP

1.34e-071839577c4b775f351794a3de06bd503eecbc8ae8577c44
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SERPINI2 CLIC5 PDGFRB TJP1 TRPC6 PTPRQ ENPEP

1.39e-071849577294b379ce4cb8fa75e432559082f93cd106aaf5
ToppCellParenchymal-NucSeq-Stromal-Pericyte-Muscle_pericyte_systemic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MAP1B PDGFRB ASIC2 TRPC6 PLET1 GRM8 ENPEP

2.29e-07198957882710bd6215e299257dd3df234292db9a2823ba
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SERPINI2 CLIC5 TRPC6 PTPRQ ENPEP TGM5

1.02e-0615595690e629681a72baacc7981b82883866a487638dbc
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SERPINI2 CLIC5 TRPC6 PTPRQ ENPEP TGM5

1.02e-06155956e7f49e2fdaf184fa6b4e685518004e7deff1316d
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SERPINI2 CLIC5 TRPC6 PTPRQ ENPEP TGM5

1.02e-061559565a872ca70ae8c30b57f45a6772d7bf565e0c2663
ToppCellRV-13._Vascular_Smooth_Muscle|RV / Chamber and Cluster_Paper

MAP1B PDGFRB PPP1R12A TRPC6 DMD ENPEP

1.28e-0616195647b3b7662cbb671ccc086dc0a0cabd65f63eb5a1
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SERPINI2 CLIC5 TJP1 TRPC6 PTPRQ ENPEP

1.64e-06168956fc80e4fecfc92458eb627013a983041d8ca025a9
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SERPINI2 CLIC5 TJP1 TRPC6 PTPRQ ENPEP

1.64e-06168956315ca578c945aeeb77acda2727f3e6db8b43f43e
ToppCellControl-Epithelial_cells-AT1|Control / group, cell type (main and fine annotations)

WWC2 CLIC5 TJP1 PTPRQ HOMER1 SCAI

2.01e-06174956548d7f2b958a2bfd2c95eb049ceaab55a559c77d
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SERPINI2 CLIC5 PDGFRB TRPC6 PTPRQ ENPEP

2.01e-06174956dbdcdec08f1fc69fcdb5d8a6d78df8ef9c374d89
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SERPINI2 CLIC5 MAP1B TJP1 TRPC6 PTPRQ

2.21e-061779564d2cdb57b427a42085c5f9affa0967b15e84dec3
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SERPINI2 CLIC5 MAP1B TJP1 TRPC6 PTPRQ

2.29e-06178956edc7143dc9959d36057cb9471681a23afcbc8cce
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SERPINI2 CLIC5 TJP1 TRPC6 PTPRQ ENPEP

2.36e-061799567394e77e665bf16d3733df91bb12907be460ab44
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

WWC2 CLIC5 TJP1 PTPRQ HOMER1 SCAI

2.36e-061799564f6ca313b78aa93557937a046c44dcf8bcc9963c
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SERPINI2 CLIC5 TJP1 TRPC6 PTPRQ ENPEP

2.52e-061819565bf7aa43f6e6ecce15c95928b91195544d6928c4
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SERPINI2 CLIC5 TJP1 TRPC6 PTPRQ ENPEP

2.52e-061819568e751f5d7cd2d328ec0196d874e8a507e8c4e1a9
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SERPINI2 CLIC5 PDGFRB TJP1 TRPC6 PTPRQ

2.68e-06183956848fc6dd129150897ee339343e83c645b6e779eb
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SERPINI2 CLIC5 TJP1 TRPC6 PTPRQ ENPEP

2.68e-06183956eb559ae3ae252d9365c24ef557dd49b78ed6d898
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1-D122|Adult / Lineage, Cell type, age group and donor

WWC2 CLIC5 TJP1 PTPRQ DMD SCAI

2.77e-06184956561592edc3083fad41b91811151b442207c65dd9
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1|Children_(3_yrs) / Lineage, Cell type, age group and donor

WWC2 CLIC5 TJP1 PTPRQ HOMER1 SCAI

2.86e-061859561c222f7285d6e3dae0354dc7e853ddc0ea55e63e
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1-D175|Adult / Lineage, Cell type, age group and donor

CACNA2D1 WWC2 CLIC5 PTPRQ DMD HOMER1

2.86e-0618595632b4e68e551d435a732f253f6ad83408c759a642
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SERPINI2 CLIC5 PDGFRB TJP1 TRPC6 PTPRQ

2.86e-061859569197f074e769d54031ec41abfc65fcc0c6552c7e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SERPINI2 CLIC5 PDGFRB TJP1 TRPC6 PTPRQ

2.86e-06185956ce7d62394b09c26ca65b8cdb280afec5e25bbb62
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SERPINI2 CLIC5 PDGFRB TJP1 TRPC6 PTPRQ

2.86e-06185956b848b63aff4d9dbb9e66a85876d4c7c6dacd0579
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

WWC2 CLIC5 TJP1 PTPRQ HOMER1 SCAI

3.04e-06187956d4b0afd9b92c47c8aa348bbd1af7eb54c3d478f2
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CLIC5 MAP1B TJP1 TRPC6 PTPRQ ENPEP

3.04e-0618795624c2a3962da364e46e98abeab5f8234376fa26bb
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Degenerative_Podocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CLIC5 MAP1B PDGFRB TJP1 PTPRQ ENPEP

3.14e-061889569db778c1d9e622a68337212296e3a1ed8f771fa5
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

WWC2 CLIC5 TJP1 PTPRQ HOMER1 SCAI

3.33e-0619095630b50d183d7649146eb1e79b47ba897355f1998a
ToppCellMesenchymal-vascular_smooth_muscle_cell|World / Lineage, Cell type, age group and donor

CACNA2D1 MAP1B PDGFRB TRPC6 DMD ENPEP

3.44e-06191956fd89fbc62aa1c73e0f659991e3bd726a0c97bd68
ToppCellParenchymal-NucSeq-Epithelial-Epi_alveolar-AT1|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

WWC2 CLIC5 TJP1 PTPRQ HOMER1 SCAI

4.11e-061979568d5097898dd01cedb04cb694cb480c931e08462c
ToppCellfacs-Heart-Unknown-3m-Endothelial-endothelial_cell_of_coronary_artery|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACE2 PTPRQ ROS1 TEX15 IQGAP3

1.30e-051419554aa4b3476dc5abefbd348353cfe711cd5fe3d52f
ToppCellfacs-Heart-Unknown-3m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACE2 PTPRQ ROS1 TEX15 IQGAP3

1.30e-05141955e40c6f1b7fbaa46b3eaa55f1b37ef360b04370a8
ToppCellfacs-Heart-Unknown-3m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACE2 PTPRQ ROS1 TEX15 IQGAP3

1.35e-05142955759fbbd15b4fb313bd6269b7f087edafebd530ef
ToppCelldroplet-Lung-nan-3m-Myeloid-Nonclassical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TUBB6 IL31RA SMPDL3B PTPRJ B4GALT5

1.93e-051539556dcab3d50ab50051955204dc4e4a64c1ca855bcd
ToppCelldroplet-Lung-nan-3m-Myeloid-non-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TUBB6 IL31RA SMPDL3B PTPRJ B4GALT5

1.93e-05153955f6ef14d949107c08cb3690e26ec91e194cb43518
ToppCellRV-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

PDGFRB PPP1R12A TRPC6 DMD ENPEP

2.39e-0516095529c9b4770d0e73d59cffc7937b179484c76b6dcc
ToppCellfacs-Lung-ENDOMUCIN-18m-Myeloid-Nonclassical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL31RA SMPDL3B ARHGAP39 XKR5 B4GALT5

2.39e-051609552020b6defbaf5b5db12af37f0103ac028a8ca76e
ToppCellfacs-Lung-ENDOMUCIN-18m-Myeloid-non-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL31RA SMPDL3B ARHGAP39 XKR5 B4GALT5

2.39e-05160955af7cf0dc5fe7c02f7d6c436f6dde766c79ff0eae
ToppCellLV-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

PDGFRB IL1RAPL2 PPP1R12A DMD ENPEP

2.77e-05165955f37fd95adc95d7753cf6e55ae819976513c7ec77
ToppCellIonocyte-iono-3|World / Class top

TUBB6 ASIC2 XKR5 CCDC93 BCO1

2.85e-051669559c4a780f8af46d7552077c7a0ae0ab1b2413e5d4
ToppCelldroplet-Lung-18m-Hematologic-myeloid-intermediate_monocyte|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TUBB6 SMPDL3B PTPRJ MCUB B4GALT5

3.02e-0516895500cff4698db14e03ca1d1b409e5ed1ad23b12615
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SERPINI2 CLIC5 TRPC6 PTPRQ ENPEP

3.02e-05168955e96859dbf51cf8c4def8ee8db132f4d874fb4381
ToppCelldroplet-Lung-18m-Hematologic-myeloid-intermediate_monocyte-intermediate_monocyte_l4|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TUBB6 SMPDL3B PTPRJ MCUB B4GALT5

3.11e-0516995590c00ab30e582b0e2a2be751e1fae9024cfb9ea6
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CLIC5 MAP1B TJP1 PTPRQ ENPEP

3.20e-0517095560bbd738c12e64e483485586c30057304884f5a6
ToppCellControl-Fibroblasts-Pericytes|Control / group, cell type (main and fine annotations)

CACNA2D1 MAP1B PDGFRB TRPC6 GRM8

3.29e-05171955080003f698f867935c2bfc55d241d3650f45a0ab
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_artery-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

TJP1 NXPH1 FGF2 TEK IQGAP3

3.29e-051719551597459c971d6befa991d59dc66b41b6a522f797
ToppCellAdult-Mesenchymal-vascular_smooth_muscle_cell|Adult / Lineage, Cell type, age group and donor

CACNA2D1 MAP1B PDGFRB TRPC6 DMD

3.38e-05172955c62cad0f4212d1e9ea1ec3143ad3c4e06aff0ebf
ToppCell3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-Pericytes-angiogenic_pericyte|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MAP1B PDGFRB PPP1R12A TRPC6 ENPEP

3.38e-05172955107417cfab7775bc1f80807115047abfb50b7a7e
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SERPINI2 CLIC5 TRPC6 PTPRQ ENPEP

3.38e-05172955381ae1c3c07d0a424f43455ec571653b192a946a
ToppCellCOVID-19-Heart-Neuronal|Heart / Disease (COVID-19 only), tissue and cell type

PTPRJ IL1RAPL2 SORCS3 ARHGAP39 INPP5F

3.47e-051739556fb5f9e6536a5d57fd8e6657b494047a2d0bc9c7
ToppCellChildren_(3_yrs)-Mesenchymal-vascular_smooth_muscle_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

CACNA2D1 MAP1B PDGFRB TRPC6 DMD

3.47e-051739555416b092321c7d9b63f0418c60f2402a138355bf
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SMPDL3B ASIC2 NGEF SORCS3 ROS1

3.57e-05174955e4d65fe121a32ac4cdd6312e7b8f867f0852e991
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_FAM95C|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SMPDL3B ASIC2 TRPC6 TEX15 GRM8

3.67e-0517595590e29945aa861082c94bb4f331161adc3a6ef899
ToppCellCOVID-19-Heart-VSMC|COVID-19 / Disease (COVID-19 only), tissue and cell type

MAP1B PDGFRB ACKR3 DMD ENPEP

3.67e-051759551125f0d3a5b2388fa77a820dea0288e824d84a82
ToppCellThalamus-Neuronal-Excitatory|Thalamus / BrainAtlas - Mouse McCarroll V32

NR2C2 MAP1B TEX15 HOMER2 CCDC136

3.77e-05176955d2bbf13d21fb7582d7e5f90cd61a4ebe1cfccd66
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SMPDL3B ASIC2 NGEF SORCS3 NXPH3

3.87e-051779554c069f0d044a96118090b85ca592a21d6b5d9399
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_A_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TUBB6 ACE2 MAP1B DMD MCUB

3.87e-051779551dc69c661e70e7e22bd9d7cf953eb638da9fd43c
ToppCelldroplet-Bladder-BLADDER-1m-Endothelial-nan|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLIC5 ASIC2 ABCD2 TEK CCDC136

3.98e-051789556bef4ef48f649c6e38ae732bc08e6d7814db588b
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_FAM95C|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

IL31RA SMPDL3B ASIC2 NGEF GRM8

4.09e-051799557954c0026754ab869b88ab7feb13c2f27d6e272d
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_FAM95C|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SMPDL3B ASIC2 TRPC6 NGEF TEX15

4.09e-05179955f65889bf1e41396979cce44a5e63f49dea2bbd9b
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L4-5_RORB_RPL31P31|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

IL1RAPL2 NGEF SORCS2 SORCS3 GRM8

4.09e-05179955b35a7f8115c997c390201da01d7cb10b10769aec
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-SMC_prolif|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TUBB6 PDGFRB TRPC6 GRM8 ENPEP

4.20e-0518095564956a85c404a2ea7e4eaf6f95ebcc52c198b7cc
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L4-5_RORB_RPL31P31|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

IL1RAPL2 SORCS2 SORCS3 DMD GRM8

4.20e-05180955b7513b9816a9cb9f3caaddb2a9fed0be1c7f9805
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

IL1RAPL2 SORCS2 SORCS3 DMD GRM8

4.20e-05180955f96c5be4705e3d338c0393d2885ac8d5beccd6fd
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CLIC5 MAP1B TJP1 PTPRQ ENPEP

4.20e-05180955d685fa2b013bc085dbef7c40956ed3043f83e483
ToppCellChildren_(3_yrs)-Mesenchymal-pericyte_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

CACNA2D1 MAP1B PDGFRB TRPC6 DMD

4.31e-05181955451b87ac95154bb80018b8dd245b4a6389d81411
ToppCellCOVID-19-Heart-Pericyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

ACE2 CACNA2D1 MAP1B PDGFRB ENPEP

4.31e-0518195533cac65ed1ea5e7bd72250495df4f850b143d5aa
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

WWC2 CLIC5 PTPRQ SORCS2 HOMER1

4.31e-05181955b45b11428d13950369347e051d4d517efb2bd4fd
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Degenerative_Podocyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CLIC5 PDGFRB TJP1 PTPRQ ENPEP

4.42e-05182955cde8fa4f42d25545abaa9ee885b4b1e24a5a8e08
ToppCelldroplet-Marrow-nan-24m-Lymphocytic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERGIC1 DNAJC3 KRTCAP2 STAB1 TMED3

4.54e-05183955b5782b18decfe85026acf42daac0670d92385861
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SMPDL3B ASIC2 TRPC6 NGEF TEX15

4.54e-0518395565f2a5895d166189a095cf7ea9dda171f0419b08
ToppCelldroplet-Marrow-nan-24m-Lymphocytic-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERGIC1 DNAJC3 KRTCAP2 STAB1 TMED3

4.54e-05183955e32847cfebba7c8bb2026e33c3c85f64819460a9
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT1-AT1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

WWC2 CLIC5 TJP1 PTPRQ SCAI

4.66e-0518495557c792e6e2fedba25d3350ffe649fd74750b579d
ToppCellFrontal_cortex-Neuronal-Excitatory|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

CACNA2D1 BTBD10 NGEF GRM8 HOMER1

4.66e-051849556e17c8151d6dc543de16d804db956c63c3fda414
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L4-5_RORB_RPL31P31|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

IL1RAPL2 NGEF SORCS2 SORCS3 GRM8

4.66e-051849559cc5c588f7c6631b3fb8a522214a09ca32947e72
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

WWC2 CLIC5 TJP1 PTPRQ SCAI

4.66e-05184955d7bd0f0c607bade67c99e9fb3578a570298bf926
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-Pericytes-angiogenic_pericyte|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MAP1B PDGFRB PPP1R12A TRPC6 ENPEP

4.78e-0518595535d39a1d04c871edcfb749653538dc5fd0054281
ToppCell(5)_Pericytes|World / Cell class and subclass of bone marrow stroma cells in homeostatis

PDGFRB PPP1R12A TRPC6 DMD ENPEP

4.91e-05186955acbca8cc048d87faf859b3e77bdb38d0a3dad71c
ToppCell(5)_Pericytes-(50)_Pericytes|World / Cell class and subclass of bone marrow stroma cells in homeostatis

PDGFRB PPP1R12A TRPC6 DMD ENPEP

4.91e-0518695567b59defdd1ed3608229cc5e2a3b480d92312afa
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

IL1RAPL2 SORCS2 ROS1 DMD DNAH14

4.91e-051869552ea5ff14861e5f91d0e6a5767c403a24045d715c
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CLIC5 MAP1B TJP1 PTPRQ ENPEP

4.91e-051869551094c7140131454b2583200e1c01e81ccab3db23
ToppCellhuman_hepatoblastoma-Hepatic_Stellate_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

CACNA2D1 MAP1B PDGFRB TRPC6 ENPEP

4.91e-05186955cb1fc4b9140666b43415e21c9b434dc9b144e9d0
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CACNA2D1 MAP1B PDGFRB TRPC6 DMD

4.91e-051869554780af76237d7af2abbe2d8d5530cdf53e3ed0b7
ToppCellEpithelial-alveolar_epithelial_cell_type_1|World / Lineage, Cell type, age group and donor

WWC2 CLIC5 TJP1 PTPRQ SCAI

4.91e-0518695509d95daa3387a4814cffaa4b798cc2810c3759d0
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1|Adult / Lineage, Cell type, age group and donor

WWC2 CLIC5 TJP1 PTPRQ SCAI

5.03e-0518795577f78aec946bc6bd85c29aee9ca978ce49f853a3
ToppCellControl-Epithelial_cells|Control / group, cell type (main and fine annotations)

WWC2 CLIC5 ROS1 DNAH14 SCAI

5.16e-05188955707ebf76cc6fb600b2f07793cf4ea9482c0de79d
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CLIC5 MAP1B TJP1 PTPRQ ENPEP

5.16e-05188955047c4e0b03fc8334e38c48977e41d26dbe229d47
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CACNA2D1 MAP1B PDGFRB TRPC6 DMD

5.29e-051899557ab1cfc1657277858339f7258a0c4ae9cb42fdf8
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PTPRJ PKP4 SORCS3 GRM8 HOMER2

5.29e-051899558c8ca3b30d9be6c854615459a7bfba82b427c8bc
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PTPRJ PKP4 SORCS3 GRM8 HOMER2

5.29e-051899555d902a4660a27548764bf04c6de152b565da835c
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CACNA2D1 ASIC2 NGEF HOMER1 SCAI

5.29e-05189955c3df0e3c50af8f1cfb4d790e668bd7f42b276992
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CACNA2D1 ASIC2 NGEF HOMER1 SCAI

5.43e-05190955d594da827e3c16644952b9589cc12b947ce36279
ToppCellFetal_29-31_weeks-Mesenchymal-vascular_smooth_muscle_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

MAP1B PDGFRB TRPC6 DMD ENPEP

5.43e-05190955d6b3a92119b210974a32af3fe9875d60eb02761e
ToppCell5'-Adult-LymphNode-Endothelial-lymphatic_endothelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TUBB6 MAP1B ACKR3 TEK HOMER3

5.43e-051909556b704deeb44e1ffa10e604d0e5612b022f6cd9a6
DrugKarakoline [39089-30-0]; Up 200; 10.6uM; PC3; HT_HG-U133A

ACE2 CACNA2D1 CLCA1 ASIC2 PKP4 TEX15 HOMER3 STAB1

1.88e-061999584297_UP
Diseasebiological sex

PTPRJ PKP4 NXPH1 SORCS3 ARHGAP39 KRTCAP2

9.10e-05230936PATO_0000047
Diseaseasymmetrical dimethylarginine measurement, serum dimethylarginine measurement

CACNA2D1 CLCA4 CLCA1

1.54e-0433933EFO_0005418, EFO_0006522
Diseaseserum metabolite measurement

CACNA2D1 CLIC5 ACKR3 NGEF SORCS3 CELA2B TEK ENDOG ENPEP PMFBP1 BCO1

1.91e-049459311EFO_0005653
Diseaseintelligence, specific language impairment, dyslexia

CCDC136 PMFBP1

2.72e-048932EFO_0004337, EFO_0005424, EFO_1001510
Disease2-hydroxystearate measurement

MUC19 TEK

3.49e-049932EFO_0021059
Diseasecognitive disorder (is_implicated_in)

FGF2 DMD

3.49e-049932DOID:1561 (is_implicated_in)
Diseasesevere acute respiratory syndrome, COVID-19

CACNA2D1 PGS1 CLIC5 SORCS2 DMD B4GALT5 TMED3

5.40e-04447937EFO_0000694, MONDO_0100096
Diseasespecific language impairment, dyslexia

CCDC136 PMFBP1

6.35e-0412932EFO_0005424, EFO_1001510
DiseaseDEAFNESS, AUTOSOMAL RECESSIVE (disorder)

CLIC5 PTPRQ

7.49e-0413932C1846647
Diseasethalamus volume change measurement

ASIC2 SORCS2

8.72e-0414932EFO_0021496
Diseasepulmonary hypertension (is_marker_for)

TRPC6 FGF2 TEK

1.10e-0364933DOID:6432 (is_marker_for)
Diseaseclostridium difficile infection

NXPH1 SORCS2 TEK PCID2

1.13e-03144934EFO_0009130
DiseaseAstrocytosis

FGF2 GRM8

1.30e-0317932C3887640
DiseaseGliosis

FGF2 GRM8

1.30e-0317932C0017639
Diseasesphingosine 1-phosphate measurement

SORCS2 DMD

1.45e-0318932EFO_0800185
Diseasewellbeing measurement

CACNA2D1 PTPRQ MUC19 SORCS3 TEX15 GRM8 SCAI STAB1

1.56e-03692938EFO_0007869
Diseasepreeclampsia

LNPEP TRPC6 PCID2

1.94e-0378933EFO_0000668
Diseasefemale reproductive system disease

ASIC2 PSMD13

2.38e-0323932EFO_0009549
Diseasefeeling nervous measurement

CACNA2D1 SORCS3 DNAH14

2.65e-0387933EFO_0009597
DiseaseS-6-hydroxywarfarin to S-warfarin ratio measurement

PDGFRB ASIC2 CCDC93

2.74e-0388933EFO_0803332
Diseasepallidum volume change measurement, age at assessment

SORCS2 GRM8

2.81e-0325932EFO_0008007, EFO_0021494
DiseaseL lactate dehydrogenase measurement

PTPRJ STAB1

3.04e-0326932EFO_0004808

Protein segments in the cluster

PeptideGeneStartEntry
YSTQYGLKSTTNYVD

PKP4

1156

Q99569
TNYVDFYSTKRPSYR

PKP4

1166

Q99569
EEYSQIIYSTKLYRF

BTBD10

331

Q9BSF8
TYFTNQTYYKVINMD

ABCD2

186

Q9UBJ2
FKSYAYTQAAYVTTS

DMD

296

P11532
YKAYQDTTLNSSSEY

DHX32

551

Q7L7V1
YFANITYDALYKNIT

B4GALT5

361

O43286
QKYLSTLLYNTANYS

BBS12

596

Q6ZW61
EYSNTRAYYFVKFKR

CGAS

241

Q8N884
NTEAFYKISTLYYQL

DNAJC3

221

Q13217
YSTIYDTIQNERTYE

CLIC5

6

Q9NZA1
SERVSYYFSYQHVTK

ASIC2

61

Q16515
YLEQSYKNYTLVTVF

NUP93

261

Q8N1F7
QDYVQKTYSEDTYRL

NR2C2

526

P49116
NTSRFYYYNASTQRT

ARHGAP39

76

Q9C0H5
NTSKYAESYRIQTYA

PARN

496

O95453
NAYTSREQTVYYAKA

PMPCB

131

O75439
YRTEVTYLNFSTSYN

PTPRJ

776

Q12913
NITKYESSLYSQEYS

MAP1B

1161

P46821
YFIVTRQDYTYSAVK

MCUB

266

Q9NWR8
KETSYTQYTVKRTYA

IL31RA

46

Q8NI17
SSYRGKYSELVTAYQ

GOLGA4

151

Q13439
SVFYDDTYNTLKYAN

KIF18A

336

Q8NI77
QSTLQRYYVYNSVSY

SMPDL3B

386

Q92485
AVTVSYFYDVTRNSY

HOMER2

31

Q9NSB8
YNTYASRLYRTVSST

FGF3

126

P11487
YYINKISSTLYQAAA

KRTCAP2

106

Q8N6L1
TVSYFYDATRNVYRI

HOMER3

36

Q9NSC5
YYSDKIQIFNASSSY

MUC19

901

Q7Z5P9
KVYLTTGYFNLTQAY

PGS1

381

Q32NB8
SYQYTVANKEYVAYS

ERGIC1

206

Q969X5
LSYVTEGRNYSKYQS

LNPEP

656

Q9UIQ6
FTVIRYISYNSYGKN

ENPEP

851

Q07075
VHSRFYDLSSKYYQT

PSMD13

151

Q9UNM6
YDIFQYQITNKSTEY

GRM8

471

O00222
AVTVSYFYDSTRNVY

HOMER1

31

Q86YM7
TKTTFYEEQGDYYSQ

IQGAP3

1496

Q86VI3
DYNVEYSAYVTASTR

PTPRQ

956

Q9UMZ3
KDDYSTAQRVTYKYY

PCID2

201

Q5JVF3
DYIRSYSVSQFQKTY

CCDC93

136

Q567U6
YYKPSIFTRVSNYND

CELA2B

246

P08218
LVNISVYAFNKSYDY

CACNA2D1

886

P54289
YYNAISVTTSYNLAR

CTR9

491

Q6PD62
YNSYDISRDTLYVSK

DENND5B

176

Q6ZUT9
YYLKTVTSASNNETY

ACKR3

181

P25106
VSNDYSFIRYYTRTL

ACE2

506

Q9BYF1
YFTYKVRYTNSSTEI

ELOC

76

Q15369
NRKYFEETGRFYYTT

DNAH14

2216

Q0VDD8
ESNNYNTYRSRKYTS

FGF2

241

P09038
VNKYYSNLTKSERYS

EEF2K

56

O00418
FYYSLTYDLTNSVQR

INPP5F

176

Q9Y2H2
SDAYYVYRLQVSSIN

PDGFRB

201

P09619
VYIAFYSTDYRLVQK

NXPH3

221

O95157
TEELQTSYYSLRQYQ

PMFBP1

101

Q8TBY8
TSYYSLRQYQSILEK

PMFBP1

106

Q8TBY8
NYSIYKRTAEAVYSI

RTTN

536

Q86VV8
YISFYSTDYKLVQKV

NXPH1

241

P58417
ATYQKYRLTFYIQSL

SORCS3

286

Q9UPU3
FYSYIRTNYSTAQST

IL1RAPL2

56

Q9NP60
KYSRSLTRSYQNVYV

ENDOG

181

Q14249
SVYITYVSNQTYQER

NGEF

361

Q8N5V2
YVSNQTYQERTYKQL

NGEF

366

Q8N5V2
FKATSANQTKYYVSY

SORCS2

356

Q96PQ0
VFSQYKNTARQYAYF

SETD3

206

Q86TU7
YAYNSNKVVSVLYTV

OR6Y1

271

Q8NGX8
VLYNSSAKVANASYY

U2SURP

601

O15042
EVYYRSKYLRSDTYN

BCO1

66

Q9HAY6
VDDNESYYKSYTSTQ

CCDC136

766

Q96JN2
STTTKFCYRYSYQDT

CLDN34

66

H7C241
YFTTYDTNGRYSVKV

CLCA1

661

A8K7I4
KNDGVYSRYFTAYTE

CLCA4

656

Q14CN2
YQQSSYTEQSYDRSF

SS18L1

281

O75177
YSNSTYYVKDQYMTV

PLET1

96

Q6UQ28
AYQTDNKKAITYTYD

TTC19

126

Q6DKK2
IYRSQSYKTGIYSVE

UBE2Q2

216

Q8WVN8
YSSQSDQIDVDYQYK

WWC2

471

Q6AWC2
QSNTYATKRDIYYTD

SPO11

126

Q9Y5K1
RINVYYNESSSQKYV

TUBB6

46

Q9BUF5
YLSVAINSYSALKNY

RNF123

866

Q5XPI4
TIYRETKKQYDSFTY

TMED3

76

Q9Y3Q3
FETEFRQYKRTYYMT

XRN1

426

Q8IZH2
FSFYSAIRQRSYYSQ

SCAI

151

Q8N9R8
RTTQIYTYFVYKTRN

SEC63

226

Q9UGP8
KTEAKSFLSQYRYYT

SPATA7

246

Q9P0W8
RTKYGYFSESSLNYQ

SERPINI2

221

O75830
ITVTFNQFTKYSYKY

STAB1

451

Q9NY15
TYLVYYAEVNDRKNS

ROS1

1486

P08922
TYVNTTLYEKFTYAG

TEK

1101

Q02763
YSQYSQYLSTDKLIR

TGM5

581

O43548
SISVYETQTKYQSYN

NSD3

76

Q9BZ95
QPTYRYESSSYTDQF

TJP1

1056

Q07157
AESKQYFEQYSRSYE

TJP1

1186

Q07157
YSYYIGAKQNEAFTT

TRPC6

656

Q9Y210
LQGYSSVSQRKYYST

TEX15

1046

Q9BXT5
EQSARLYTVAYYFTT

XKR5

16

Q6UX68
SYQSFQTFRLYREYK

GTF3C1

1446

Q12789
NTISYSLQDYIFQSY

UGT2A2

221

P0DTE5
YYKIFDNIDRSVIYS

PP2D1

146

A8MPX8
QKYSRTYDETYQRYR

PPP1R12A

756

O14974