Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionNotch binding

DNER ADAM17 DLL1 NOTCH1

3.16e-0727434GO:0005112
GeneOntologyMolecularFunctioncalcium ion binding

DNER LRP2 UMOD FBN1 STAB2 DLL1 NOTCH1 EGFEM1P VCAN CRB1

3.24e-067494310GO:0005509
GeneOntologyMolecularFunctioncargo receptor activity

LRP2 STAB2 EGFEM1P INSR

3.32e-0585434GO:0038024
GeneOntologyMolecularFunctionextracellular matrix structural constituent

LAMB2 LAMC1 FBN1 MUC2 VCAN

5.05e-05188435GO:0005201
GeneOntologyMolecularFunctionglycosaminoglycan binding

CCL15 FBN1 STAB2 ECM2 VCAN

2.66e-04268435GO:0005539
GeneOntologyMolecularFunctionextracellular matrix constituent conferring elasticity

LAMC1 FBN1

2.95e-0412432GO:0030023
GeneOntologyMolecularFunctioninsulin-like growth factor I binding

LRP2 INSR

3.48e-0413432GO:0031994
GeneOntologyMolecularFunctionstructural molecule activity conferring elasticity

LAMC1 FBN1

4.05e-0414432GO:0097493
GeneOntologyMolecularFunctionlow-density lipoprotein particle receptor activity

LRP2 STAB2

5.33e-0416432GO:0005041
GeneOntologyMolecularFunctionintegrin binding

LAMB2 ADAM17 FBN1 ECM2

5.39e-04175434GO:0005178
GeneOntologyMolecularFunctionstructural molecule activity

LAMB2 LAMC1 FBN1 MUC2 VCAN KRT40 INSR OTOG

5.50e-04891438GO:0005198
GeneOntologyMolecularFunctioninsulin-like growth factor binding

LRP2 INSR

7.57e-0419432GO:0005520
GeneOntologyMolecularFunctionlipoprotein particle receptor activity

LRP2 STAB2

9.27e-0421432GO:0030228
GeneOntologyMolecularFunctionscavenger receptor activity

STAB2 EGFEM1P

1.54e-0327432GO:0005044
GeneOntologyMolecularFunctionhyaluronic acid binding

STAB2 VCAN

1.77e-0329432GO:0005540
GeneOntologyMolecularFunctionPDZ domain binding

LRP2 ADAM17 CNTNAP2

2.35e-03123433GO:0030165
GeneOntologyBiologicalProcessmuscle structure development

DNER LRP2 LAMB2 LAMC1 CACNA1H CCL15 PLG DLL1 NOTCH1 ZFPM2 CNTNAP2

7.94e-078584211GO:0061061
GeneOntologyBiologicalProcessgliogenesis

DNER LRP2 LAMB2 DLL1 NOTCH1 VCAN CRB1 CNTNAP2

2.31e-06435428GO:0042063
GeneOntologyBiologicalProcessglial cell differentiation

DNER LAMB2 DLL1 NOTCH1 VCAN CRB1 CNTNAP2

3.50e-06321427GO:0010001
GeneOntologyBiologicalProcesslateral inhibition

TM2D3 DLL1

1.21e-053422GO:0046331
GeneOntologyBiologicalProcesscell-cell signaling involved in cell fate commitment

TM2D3 DLL1

1.21e-053422GO:0045168
GeneOntologyBiologicalProcessregulation of integrin-mediated signaling pathway

LAMB2 LAMC1 TIMP1

1.35e-0523423GO:2001044
GeneOntologyBiologicalProcessmuscle organ development

DNER LRP2 CACNA1H DLL1 NOTCH1 ZFPM2 CNTNAP2

2.56e-05436427GO:0007517
GeneOntologyBiologicalProcesscardiac septum morphogenesis

LRP2 NSD2 NOTCH1 ZFPM2

3.20e-0589424GO:0060411
GeneOntologyBiologicalProcessventricular septum development

LRP2 NSD2 NOTCH1 ZFPM2

3.49e-0591424GO:0003281
GeneOntologyBiologicalProcessmitral valve formation

NOTCH1 ZFPM2

4.03e-055422GO:0003192
GeneOntologyBiologicalProcessnegative regulation of inner ear receptor cell differentiation

DLL1 NOTCH1

4.03e-055422GO:2000981
GeneOntologyBiologicalProcesscompartment pattern specification

DLL1 NOTCH1

4.03e-055422GO:0007386
GeneOntologyBiologicalProcessnegative regulation of inner ear auditory receptor cell differentiation

DLL1 NOTCH1

4.03e-055422GO:0045608
GeneOntologyBiologicalProcessnegative regulation of mechanoreceptor differentiation

DLL1 NOTCH1

4.03e-055422GO:0045632
GeneOntologyBiologicalProcessheart morphogenesis

LRP2 DLL1 NSD2 NOTCH1 ZFPM2 INSR

4.44e-05321426GO:0003007
GeneOntologyBiologicalProcesscoronary vasculature morphogenesis

LRP2 NOTCH1 ZFPM2

4.50e-0534423GO:0060977
GeneOntologyBiologicalProcessnegative regulation of myoblast differentiation

CCL15 DLL1 NOTCH1

4.50e-0534423GO:0045662
GeneOntologyBiologicalProcesspositive regulation of growth

ADAM17 BCL11A DLL1 NOTCH1 ZFPM2 INSR

6.01e-05339426GO:0045927
GeneOntologyBiologicalProcessinner ear receptor cell fate commitment

DLL1 NOTCH1

6.04e-056422GO:0060120
GeneOntologyBiologicalProcessauditory receptor cell fate commitment

DLL1 NOTCH1

6.04e-056422GO:0009912
GeneOntologyBiologicalProcessinhibition of neuroepithelial cell differentiation

DLL1 NOTCH1

6.04e-056422GO:0002085
GeneOntologyBiologicalProcessarterial endothelial cell differentiation

DLL1 NOTCH1

6.04e-056422GO:0060842
GeneOntologyBiologicalProcessNotch signaling pathway

DNER ADAM17 TM2D3 DLL1 NOTCH1

6.53e-05210425GO:0007219
GeneOntologyBiologicalProcessregulation of somitogenesis

DLL1 NOTCH1

8.45e-057422GO:0014807
GeneOntologyBiologicalProcessmuscle cell differentiation

DNER LAMB2 LAMC1 CACNA1H DLL1 NOTCH1 CNTNAP2

8.89e-05531427GO:0042692
GeneOntologyBiologicalProcesskidney development

LRP2 UMOD LAMB2 FBN1 DLL1 NOTCH1

1.00e-04372426GO:0001822
GeneOntologyBiologicalProcesspositive regulation of cell population proliferation

LRP2 LAMC1 ADAM17 DLL1 TIMP1 NOTCH1 VCAN ZFPM2 INSR CDC7

1.06e-0411904210GO:0008284
GeneOntologyBiologicalProcesscell morphogenesis involved in neuron differentiation

LRP2 LAMB2 LAMC1 ADAM17 BCL11A HECW1 NOTCH1 CNTNAP2

1.14e-04748428GO:0048667
GeneOntologyBiologicalProcesspositive regulation of developmental growth

BCL11A DLL1 NOTCH1 ZFPM2 INSR

1.18e-04238425GO:0048639
GeneOntologyBiologicalProcessrenal system development

LRP2 UMOD LAMB2 FBN1 DLL1 NOTCH1

1.23e-04386426GO:0072001
GeneOntologyBiologicalProcessheart development

LRP2 FBN1 DLL1 NSD2 NOTCH1 VCAN ZFPM2 INSR

1.24e-04757428GO:0007507
GeneOntologyBiologicalProcessnephron epithelium development

UMOD LAMB2 DLL1 NOTCH1

1.32e-04128424GO:0072009
GeneOntologyBiologicalProcessaxonogenesis

LRP2 LAMB2 LAMC1 ADAM17 BCL11A NOTCH1 CNTNAP2

1.32e-04566427GO:0007409
GeneOntologyBiologicalProcessregulation of female gonad development

ZFPM2 INSR

1.44e-049422GO:2000194
GeneOntologyBiologicalProcessatrioventricular valve formation

NOTCH1 ZFPM2

1.44e-049422GO:0003190
GeneOntologyBiologicalProcesscardiac septum development

LRP2 NSD2 NOTCH1 ZFPM2

1.57e-04134424GO:0003279
GeneOntologyBiologicalProcessmyoblast differentiation

CCL15 PLG DLL1 NOTCH1

1.67e-04136424GO:0045445
GeneOntologyBiologicalProcesspositive regulation of Notch signaling pathway

TM2D3 DLL1 NOTCH1

1.71e-0453423GO:0045747
GeneOntologyBiologicalProcesscoronary artery morphogenesis

LRP2 NOTCH1

1.80e-0410422GO:0060982
GeneOntologyBiologicalProcessnegative regulation of cell-cell adhesion mediated by cadherin

PLG NOTCH1

1.80e-0410422GO:2000048
GeneOntologyBiologicalProcessNotch receptor processing

DNER ADAM17

1.80e-0410422GO:0007220
GeneOntologyBiologicalProcessloop of Henle development

UMOD DLL1

1.80e-0410422GO:0072070
GeneOntologyBiologicalProcessdistal tubule development

UMOD NOTCH1

1.80e-0410422GO:0072017
GeneOntologyBiologicalProcessneuron projection morphogenesis

LRP2 LAMB2 LAMC1 ADAM17 BCL11A HECW1 NOTCH1 CNTNAP2

1.84e-04802428GO:0048812
GeneOntologyBiologicalProcessventricular septum morphogenesis

NSD2 NOTCH1 ZFPM2

2.02e-0456423GO:0060412
GeneOntologyBiologicalProcessepithelial cell development

LAMB2 RAPGEF6 DLL1 MUC2 NOTCH1

2.08e-04269425GO:0002064
GeneOntologyBiologicalProcessplasma membrane bounded cell projection morphogenesis

LRP2 LAMB2 LAMC1 ADAM17 BCL11A HECW1 NOTCH1 CNTNAP2

2.12e-04819428GO:0120039
GeneOntologyBiologicalProcessregulation of basement membrane organization

LAMB2 LAMC1

2.20e-0411422GO:0110011
GeneOntologyBiologicalProcesscell projection morphogenesis

LRP2 LAMB2 LAMC1 ADAM17 BCL11A HECW1 NOTCH1 CNTNAP2

2.25e-04826428GO:0048858
GeneOntologyBiologicalProcessventricular cardiac muscle tissue morphogenesis

LRP2 NOTCH1 ZFPM2

2.36e-0459423GO:0055010
GeneOntologyBiologicalProcessregulation of inner ear receptor cell differentiation

DLL1 NOTCH1

2.64e-0412422GO:2000980
GeneOntologyBiologicalProcessregulation of inner ear auditory receptor cell differentiation

DLL1 NOTCH1

2.64e-0412422GO:0045607
GeneOntologyBiologicalProcessregulation of mechanoreceptor differentiation

DLL1 NOTCH1

2.64e-0412422GO:0045631
GeneOntologyBiologicalProcessaxon guidance

LRP2 LAMB2 LAMC1 ADAM17 NOTCH1

2.72e-04285425GO:0007411
GeneOntologyBiologicalProcessneuron projection guidance

LRP2 LAMB2 LAMC1 ADAM17 NOTCH1

2.77e-04286425GO:0097485
GeneOntologyBiologicalProcessaxon development

LRP2 LAMB2 LAMC1 ADAM17 BCL11A NOTCH1 CNTNAP2

2.86e-04642427GO:0061564
GeneOntologyBiologicalProcessfemale sex differentiation

LRP2 NOTCH1 ZFPM2 INSR

2.89e-04157424GO:0046660
GeneOntologyBiologicalProcesscollecting duct development

UMOD NOTCH1

3.11e-0413422GO:0072044
GeneOntologyBiologicalProcesscardiac chamber morphogenesis

LRP2 NSD2 NOTCH1 ZFPM2

3.18e-04161424GO:0003206
GeneOntologyBiologicalProcesscardiac ventricle development

LRP2 NSD2 NOTCH1 ZFPM2

3.18e-04161424GO:0003231
GeneOntologyBiologicalProcesskidney epithelium development

UMOD LAMB2 DLL1 NOTCH1

3.25e-04162424GO:0072073
GeneOntologyBiologicalProcessmyotube differentiation

DNER CACNA1H NOTCH1 CNTNAP2

3.41e-04164424GO:0014902
GeneOntologyBiologicalProcesspositive regulation of integrin-mediated signaling pathway

LAMB2 LAMC1

3.63e-0414422GO:2001046
GeneOntologyBiologicalProcessleft/right axis specification

DLL1 NOTCH1

3.63e-0414422GO:0070986
GeneOntologyBiologicalProcessmitral valve morphogenesis

NOTCH1 ZFPM2

4.18e-0415422GO:0003183
GeneOntologyBiologicalProcessregulation of timing of cell differentiation

DLL1 NOTCH1

4.18e-0415422GO:0048505
GeneOntologyBiologicalProcessblood vessel endothelial cell differentiation

DLL1 NOTCH1

4.18e-0415422GO:0060837
GeneOntologyBiologicalProcessnephron development

UMOD LAMB2 DLL1 NOTCH1

4.26e-04174424GO:0072006
GeneOntologyBiologicalProcessdevelopmental growth

LAMB2 BCL11A PLG DLL1 NOTCH1 ZFPM2 INSR CNTNAP2

4.35e-04911428GO:0048589
GeneOntologyBiologicalProcessmitral valve development

NOTCH1 ZFPM2

4.77e-0416422GO:0003174
GeneOntologyBiologicalProcessnegative regulation of epidermis development

DLL1 NOTCH1

4.77e-0416422GO:0045683
GeneOntologyBiologicalProcessnegative regulation of epidermal cell differentiation

DLL1 NOTCH1

4.77e-0416422GO:0045605
GeneOntologyBiologicalProcessventricular cardiac muscle tissue development

LRP2 NOTCH1 ZFPM2

4.98e-0476423GO:0003229
GeneOntologyBiologicalProcesscirculatory system development

LRP2 FBN1 STAB2 PLG DLL1 NSD2 NOTCH1 VCAN ZFPM2 INSR

5.04e-0414424210GO:0072359
GeneOntologyBiologicalProcesscardiac muscle tissue morphogenesis

LRP2 NOTCH1 ZFPM2

5.17e-0477423GO:0055008
GeneOntologyBiologicalProcesshair cell differentiation

LAMC1 DLL1 NOTCH1

5.37e-0478423GO:0035315
GeneOntologyBiologicalProcessheart valve formation

NOTCH1 ZFPM2

5.40e-0417422GO:0003188
GeneOntologyBiologicalProcessregulation of development, heterochronic

DLL1 NOTCH1

5.40e-0417422GO:0040034
GeneOntologyBiologicalProcesscell morphogenesis

LRP2 LAMB2 LAMC1 ADAM17 BCL11A HECW1 NOTCH1 CRB1 CNTNAP2

5.57e-041194429GO:0000902
GeneOntologyBiologicalProcessneuron development

LRP2 LAMB2 LAMC1 ADAM17 BCL11A HECW1 NOTCH1 CRB1 OTOG CNTNAP2

5.65e-0414634210GO:0048666
GeneOntologyBiologicalProcesspositive regulation of neural precursor cell proliferation

LRP2 NOTCH1 VCAN

5.78e-0480423GO:2000179
GeneOntologyBiologicalProcessnegative regulation of BMP signaling pathway

LRP2 FBN1 NOTCH1

5.78e-0480423GO:0030514
GeneOntologyBiologicalProcessvasculogenesis involved in coronary vascular morphogenesis

NOTCH1 ZFPM2

6.07e-0418422GO:0060979
GeneOntologyBiologicalProcessregulation of gonad development

ZFPM2 INSR

6.07e-0418422GO:1905939
GeneOntologyBiologicalProcesscoronary vasculature development

LRP2 NOTCH1 ZFPM2

6.44e-0483423GO:0060976
GeneOntologyBiologicalProcessnegative regulation of multicellular organismal process

ADAM17 BCL11A FBN1 PLG DLL1 TIMP1 NOTCH1 ZFPM2 INSR CNTNAP2

6.45e-0414884210GO:0051241
GeneOntologyBiologicalProcessregulation of extracellular matrix organization

LAMB2 LAMC1 NOTCH1

6.67e-0484423GO:1903053
GeneOntologyBiologicalProcessregulation of muscle cell differentiation

LAMB2 LAMC1 DLL1 NOTCH1

7.06e-04199424GO:0051147
GeneOntologyBiologicalProcessgrowth

LAMB2 ADAM17 BCL11A PLG DLL1 NOTCH1 ZFPM2 INSR CNTNAP2

7.11e-041235429GO:0040007
GeneOntologyBiologicalProcessepithelial cell fate commitment

DLL1 NOTCH1

7.51e-0420422GO:0072148
GeneOntologyBiologicalProcesscardiac ventricle morphogenesis

LRP2 NOTCH1 ZFPM2

7.64e-0488423GO:0003208
GeneOntologyBiologicalProcessretina morphogenesis in camera-type eye

DLL1 NOTCH1 CRB1

8.15e-0490423GO:0060042
GeneOntologyBiologicalProcesscardiac right ventricle morphogenesis

NOTCH1 ZFPM2

8.29e-0421422GO:0003215
GeneOntologyBiologicalProcessregulation of cell-cell adhesion mediated by cadherin

PLG NOTCH1

8.29e-0421422GO:2000047
GeneOntologyBiologicalProcessresponse to follicle-stimulating hormone

PAPPA NOTCH1

8.29e-0421422GO:0032354
GeneOntologyBiologicalProcessglandular epithelial cell differentiation

DLL1 MUC2 NOTCH1

8.42e-0491423GO:0002067
GeneOntologyBiologicalProcessanimal organ morphogenesis

LRP2 LAMB2 LAMC1 DLL1 NSD2 NOTCH1 ZFPM2 CRB1 INSR

8.64e-041269429GO:0009887
GeneOntologyBiologicalProcessregulation of myoblast differentiation

CCL15 DLL1 NOTCH1

8.69e-0492423GO:0045661
GeneOntologyBiologicalProcessmuscle tissue development

DNER LRP2 DLL1 NOTCH1 ZFPM2 CNTNAP2

8.75e-04558426GO:0060537
GeneOntologyBiologicalProcessretina development in camera-type eye

LAMB2 DLL1 NOTCH1 CRB1

8.79e-04211424GO:0060041
GeneOntologyCellularComponentapical plasma membrane

LRP2 UMOD ADAM17 RAPGEF6 DLL1 NOTCH1 CRB1 OTOG

8.28e-06487458GO:0016324
GeneOntologyCellularComponentextracellular matrix

LAMB2 LAMC1 FBN1 PLG TIMP1 MUC2 ECM2 VCAN OTOG

9.01e-06656459GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

LAMB2 LAMC1 FBN1 PLG TIMP1 MUC2 ECM2 VCAN OTOG

9.23e-06658459GO:0030312
GeneOntologyCellularComponentlaminin-11 complex

LAMB2 LAMC1

1.36e-053452GO:0043260
GeneOntologyCellularComponentcollagen-containing extracellular matrix

LAMB2 LAMC1 FBN1 PLG TIMP1 MUC2 ECM2 VCAN

1.53e-05530458GO:0062023
GeneOntologyCellularComponentapical part of cell

LRP2 UMOD ADAM17 RAPGEF6 DLL1 NOTCH1 CRB1 OTOG

3.37e-05592458GO:0045177
GeneOntologyCellularComponentendoplasmic reticulum lumen

LAMB2 LAMC1 ADAM17 FBN1 TIMP1 VCAN

7.41e-05332456GO:0005788
GeneOntologyCellularComponentcell surface

LRP2 UMOD ADAM17 STAB2 FCRL5 PLG NOTCH1 VCAN INSR CNTNAP2

1.00e-0411114510GO:0009986
GeneOntologyCellularComponentbasement membrane

LAMB2 LAMC1 FBN1 TIMP1

1.37e-04122454GO:0005604
GeneOntologyCellularComponentlaminin complex

LAMB2 LAMC1

2.02e-0410452GO:0043256
GeneOntologyCellularComponentprotein complex involved in cell-matrix adhesion

LAMB2 LAMC1

6.04e-0417452GO:0098637
GeneOntologyCellularComponentmembrane raft

CACNA1H ADAM17 DLL1 INSR CNTNAP2

1.05e-03362455GO:0045121
GeneOntologyCellularComponentmembrane microdomain

CACNA1H ADAM17 DLL1 INSR CNTNAP2

1.07e-03364455GO:0098857
GeneOntologyCellularComponentGolgi lumen

UMOD MUC2 VCAN

1.67e-03109453GO:0005796
GeneOntologyCellularComponentcell projection membrane

LRP2 UMOD ADAM17 INSR CNTNAP2

2.26e-03431455GO:0031253
GeneOntologyCellularComponentsynaptic cleft

LAMB2 LAMC1

2.29e-0333452GO:0043083
GeneOntologyCellularComponentplasma membrane raft

CACNA1H INSR CNTNAP2

3.90e-03147453GO:0044853
GeneOntologyCellularComponentvoltage-gated calcium channel complex

CACNA1H SLCO6A1

4.42e-0346452GO:0005891
GeneOntologyCellularComponentexternal side of plasma membrane

LRP2 STAB2 FCRL5 PLG INSR

4.99e-03519455GO:0009897
GeneOntologyCellularComponentprotein complex involved in cell adhesion

LAMB2 LAMC1

7.17e-0359452GO:0098636
HumanPhenoHypoplasia of the iris

LRP2 LAMB2 FBN1 NSD2

5.34e-0635184HP:0007676
HumanPhenoMotor stereotypy

CACNA1H BCL11A ZBTB20 DLL1 NSD2 CRB1 CNTNAP2

2.65e-05280187HP:0000733
MousePhenohemorrhage

LAMC1 ADAM17 TM2D3 FBN1 ZBTB20 PLG DLL1 TIMP1 NOTCH1 VCAN ZFPM2

1.90e-076643311MP:0001914
MousePhenoabnormal blood circulation

LAMC1 ADAM17 TM2D3 FBN1 ZBTB20 PLG DLL1 TIMP1 NOTCH1 VCAN ZFPM2

2.09e-068453311MP:0002128
MousePhenointernal hemorrhage

LAMC1 ADAM17 FBN1 ZBTB20 PLG TIMP1 NOTCH1 VCAN

2.43e-06387338MP:0001634
MousePhenoabnormal heart right ventricle morphology

LRP2 ADAM17 FBN1 VCAN ZFPM2

2.99e-05156335MP:0003920
MousePhenoabnormal blood vessel physiology

CACNA1H ADAM17 FBN1 PLG TIMP1 NOTCH1 CRB1

3.04e-05394337MP:0000249
MousePhenoabnormal vasculature physiology

CACNA1H ADAM17 FBN1 PLG TIMP1 NOTCH1 CRB1

3.56e-05404337MP:0031170
MousePhenothick semilunar valve

ADAM17 NOTCH1 ZFPM2

4.66e-0530333MP:0031584
MousePhenoaneurysm

LAMC1 FBN1 TIMP1

7.45e-0535333MP:0003279
MousePhenoabnormal blood vessel morphology

LRP2 LAMC1 CACNA1H ADAM17 FBN1 PLG DLL1 TIMP1 NOTCH1 VCAN ZFPM2 CRB1

7.63e-0514723312MP:0001614
MousePhenoenlarged pulmonary valve

ADAM17 ZFPM2

8.06e-056332MP:0010600
MousePhenolethality during fetal growth through weaning, complete penetrance

LRP2 LAMB2 LAMC1 ADAM17 BCL11A FBN1 DLL1 NSD2 VCAN ZFPM2 INSR

9.77e-0512693311MP:0011111
MousePhenopathological neovascularization

ADAM17 PLG NOTCH1 CRB1

1.16e-04108334MP:0003711
MousePhenoabnormal heart left ventricle morphology

LRP2 ADAM17 FBN1 NOTCH1 VCAN ZFPM2

1.97e-04369336MP:0003921
MousePhenodilated heart atrium

FBN1 VCAN ZFPM2

2.05e-0449333MP:0003140
MousePhenoenlarged semilunar valve

ADAM17 ZFPM2

2.93e-0411332MP:0031580
MousePhenoabnormal lung development

LAMC1 ADAM17 FBN1 ZFPM2

3.32e-04142334MP:0001176
MousePhenoventricular septal defect

LRP2 ADAM17 NSD2 VCAN ZFPM2

3.38e-04261335MP:0010402
MousePhenoeye hemorrhage

ZBTB20 PLG VCAN

3.74e-0460333MP:0006203
MousePhenoabnormal CNS glial cell morphology

DNER LAMB2 LAMC1 CRB1 CNTNAP2

4.08e-04272335MP:0000952
MousePhenoaortic aneurysm

FBN1 TIMP1

4.83e-0414332MP:0006278
MousePhenodecreased basal metabolism

UMOD DLL1

4.83e-0414332MP:0020234
MousePhenoabnormal artery morphology

LRP2 FBN1 DLL1 TIMP1 NOTCH1 ZFPM2

5.05e-04440336MP:0002191
MousePhenoabnormal respiratory system development

LAMC1 ADAM17 FBN1 ZFPM2

5.22e-04160334MP:0003115
MousePhenoabnormal mitral valve cusp morphology

ADAM17 FBN1

5.57e-0415332MP:0010614
MousePhenoabnormal heart valve morphology

ADAM17 FBN1 NOTCH1 ZFPM2

5.60e-04163334MP:0000285
MousePhenoabnormal atrioventricular valve morphology

ADAM17 FBN1 ZFPM2

5.65e-0469333MP:0002745
MousePhenoabnormal aortic valve morphology

ADAM17 NOTCH1 ZFPM2

6.40e-0472333MP:0002747
MousePhenoabnormal heart left ventricle outflow tract morphology

ADAM17 NOTCH1 ZFPM2

6.40e-0472333MP:0010429
MousePhenothick pulmonary valve

ADAM17 ZFPM2

7.19e-0417332MP:0010601
MousePhenoabnormal heart atrium and ventricle connection

ADAM17 FBN1 ZFPM2

7.21e-0475333MP:0010435
MousePhenoabnormal muscle morphology

LRP2 LAMC1 CACNA1H ADAM17 FBN1 DLL1 NOTCH1 ZFPM2 INSR

7.96e-041106339MP:0002108
MousePhenoincreased circulating estradiol level

PAPPA TIMP1

8.08e-0418332MP:0005182
MousePhenoabnormal cardiac epithelial to mesenchymal transition

NOTCH1 ZFPM2

8.08e-0418332MP:0008825
MousePhenoabnormal respiratory conducting tube morphology

LAMC1 ADAM17 FBN1

8.39e-0479333MP:0004391
MousePhenoabnormal cardiac muscle tissue morphology

LRP2 CACNA1H ADAM17 FBN1 NOTCH1 ZFPM2

8.80e-04489336MP:0010630
MousePhenoincreased circulating estrogen level

PAPPA TIMP1

9.01e-0419332MP:0003370
MousePhenothick aortic valve cusps

ADAM17 NOTCH1

9.01e-0419332MP:0010593
MousePhenoabnormal trachea morphology

CACNA1H FBN1 PLG

9.02e-0481333MP:0002282
MousePhenoabnormal Muller cell morphology

LAMB2 CRB1

1.00e-0320332MP:0005547
MousePhenothick lung-associated mesenchyme

LAMC1 ADAM17

1.00e-0320332MP:0011143
MousePhenoabnormal interventricular septum morphology

LRP2 ADAM17 NSD2 VCAN ZFPM2

1.15e-03342335MP:0000281
DomainEGF-like_dom

DNER LRP2 UMOD LAMB2 LAMC1 FBN1 STAB2 DLL1 NOTCH1 VCAN CRB1 OTOG CNTNAP2

3.89e-152494113IPR000742
DomainEGF-like_CS

DNER LRP2 UMOD LAMB2 LAMC1 ADAM17 FBN1 STAB2 DLL1 NOTCH1 VCAN CRB1 CNTNAP2

7.15e-152614113IPR013032
DomainGrowth_fac_rcpt_

DNER LRP2 UMOD LAMB2 LAMC1 FBN1 STAB2 DLL1 NOTCH1 CRB1 INSR

2.46e-141564111IPR009030
DomainEGF

DNER LRP2 UMOD LAMB2 LAMC1 FBN1 STAB2 DLL1 NOTCH1 VCAN CRB1 CNTNAP2

6.80e-142354112SM00181
DomainEGF_1

DNER LRP2 UMOD LAMB2 LAMC1 FBN1 STAB2 DLL1 NOTCH1 VCAN CRB1 CNTNAP2

1.80e-132554112PS00022
DomainEGF_2

DNER LRP2 UMOD LAMB2 LAMC1 FBN1 STAB2 DLL1 NOTCH1 VCAN CRB1 CNTNAP2

2.84e-132654112PS01186
DomainEGF_3

DNER LRP2 UMOD FBN1 STAB2 DLL1 NOTCH1 VCAN CRB1 OTOG CNTNAP2

2.24e-122354111PS50026
DomainEGF_CA

DNER LRP2 UMOD FBN1 STAB2 DLL1 NOTCH1 VCAN CRB1

4.72e-12122419SM00179
DomainEGF-like_Ca-bd_dom

DNER LRP2 UMOD FBN1 STAB2 DLL1 NOTCH1 VCAN CRB1

5.47e-12124419IPR001881
DomainEGF

DNER LRP2 UMOD STAB2 DLL1 NOTCH1 VCAN CRB1 CNTNAP2

6.33e-12126419PF00008
DomainEGF_Ca-bd_CS

DNER LRP2 UMOD FBN1 DLL1 NOTCH1 VCAN CRB1

3.27e-1197418IPR018097
DomainEGF_CA

DNER LRP2 UMOD FBN1 DLL1 NOTCH1 VCAN CRB1

3.87e-1199418PS01187
DomainASX_HYDROXYL

DNER LRP2 UMOD FBN1 DLL1 NOTCH1 VCAN CRB1

4.20e-11100418PS00010
DomainEGF-type_Asp/Asn_hydroxyl_site

DNER LRP2 UMOD FBN1 DLL1 NOTCH1 VCAN CRB1

6.73e-11106418IPR000152
DomainhEGF

DNER DLL1 NOTCH1 CRB1

3.94e-0728414PF12661
DomainTIL_dom

LRP2 MUC2 OTOG

3.51e-0614413IPR002919
DomainEGF_extracell

DNER LRP2 STAB2 NOTCH1

8.92e-0660414IPR013111
DomainEGF_2

DNER LRP2 STAB2 NOTCH1

8.92e-0660414PF07974
DomainEGF_CA

LRP2 UMOD FBN1 NOTCH1

3.73e-0586414PF07645
DomainEGF_LAM_2

LAMB2 LAMC1 STAB2

3.83e-0530413PS50027
DomainEGF_LAM_1

LAMB2 LAMC1 STAB2

3.83e-0530413PS01248
DomainEGF_Lam

LAMB2 LAMC1 STAB2

6.12e-0535413SM00180
DomainLaminin_EGF

LAMB2 LAMC1 STAB2

7.85e-0538413IPR002049
Domain-

BCL11A ZBTB20 ZNF543 ZBTB3 ZNF691 ZFPM2 ZFP64 ZNF77

9.66e-056794183.30.160.60
DomainNotch_dom

PAPPA NOTCH1

9.81e-057412IPR000800
DomainNotch

PAPPA NOTCH1

9.81e-057412PF00066
DomainNL

PAPPA NOTCH1

9.81e-057412SM00004
DomainVWF_dom

MUC2 ECM2 OTOG

1.06e-0442413IPR001007
Domainzf-C2H2

BCL11A ZBTB20 ZNF543 ZBTB3 ZNF691 ZFPM2 ZFP64 ZNF77

1.11e-04693418PF00096
DomainZnf_C2H2/integrase_DNA-bd

BCL11A ZBTB20 ZNF543 ZBTB3 ZNF691 ZFPM2 ZFP64 ZNF77

1.12e-04694418IPR013087
DomainZINC_FINGER_C2H2_2

BCL11A ZBTB20 ZNF543 ZBTB3 ZNF691 ZFPM2 ZFP64 ZNF77

2.40e-04775418PS50157
DomainZINC_FINGER_C2H2_1

BCL11A ZBTB20 ZNF543 ZBTB3 ZNF691 ZFPM2 ZFP64 ZNF77

2.44e-04777418PS00028
Domain-

UMOD STAB2

2.55e-04114122.40.155.10
DomainGFP-like

UMOD STAB2

2.55e-0411412IPR023413
DomainZnf_C2H2-like

BCL11A ZBTB20 ZNF543 ZBTB3 ZNF691 ZFPM2 ZFP64 ZNF77

2.87e-04796418IPR015880
DomainEGF_3

UMOD STAB2

3.06e-0412412PF12947
DomainTIL

MUC2 OTOG

3.06e-0412412PF01826
DomainEGF_dom

UMOD STAB2

3.06e-0412412IPR024731
DomainC8

MUC2 OTOG

3.06e-0412412PF08742
DomainZnf_C2H2

BCL11A ZBTB20 ZNF543 ZBTB3 ZNF691 ZFPM2 ZFP64 ZNF77

3.10e-04805418IPR007087
DomainZnF_C2H2

BCL11A ZBTB20 ZNF543 ZBTB3 ZNF691 ZFPM2 ZFP64 ZNF77

3.18e-04808418SM00355
DomainLINK

STAB2 VCAN

3.61e-0413412SM00445
DomainUnchr_dom_Cys-rich

MUC2 OTOG

3.61e-0413412IPR014853
DomainLink_dom

STAB2 VCAN

3.61e-0413412IPR000538
DomainC8

MUC2 OTOG

3.61e-0413412SM00832
DomainXlink

STAB2 VCAN

3.61e-0413412PF00193
DomainLINK_1

STAB2 VCAN

3.61e-0413412PS01241
DomainLINK_2

STAB2 VCAN

3.61e-0413412PS50963
DomainVWD

MUC2 OTOG

5.53e-0416412SM00216
DomainVWF_type-D

MUC2 OTOG

5.53e-0416412IPR001846
DomainLaminin_N

LAMB2 LAMC1

5.53e-0416412IPR008211
DomainLAMININ_NTER

LAMB2 LAMC1

5.53e-0416412PS51117
DomainVWFD

MUC2 OTOG

5.53e-0416412PS51233
DomainLaminin_N

LAMB2 LAMC1

5.53e-0416412PF00055
DomainVWD

MUC2 OTOG

5.53e-0416412PF00094
DomainLamNT

LAMB2 LAMC1

5.53e-0416412SM00136
DomainVWC_out

MUC2 OTOG

7.85e-0419412SM00215
DomainCT

MUC2 OTOG

1.06e-0322412SM00041
DomainGalactose-bd-like

LAMB2 LAMC1 CNTNAP2

1.15e-0394413IPR008979
Domain-

PAPPA CRB1 CNTNAP2

1.18e-03954132.60.120.200
DomainCys_knot_C

MUC2 OTOG

1.37e-0325412IPR006207
DomainCTCK_2

MUC2 OTOG

1.37e-0325412PS01225
DomaincEGF

LRP2 FBN1

1.48e-0326412IPR026823
DomaincEGF

LRP2 FBN1

1.48e-0326412PF12662
DomainLaminin_EGF

LAMB2 LAMC1

2.67e-0335412PF00053
DomainVWFC_1

MUC2 ECM2

2.83e-0336412PS01208
DomainVWC

MUC2 ECM2

3.14e-0338412SM00214
DomainVWFC_2

MUC2 ECM2

3.14e-0338412PS50184
DomainLAM_G_DOMAIN

CRB1 CNTNAP2

3.14e-0338412PS50025
DomainKeratin_B2_2

KRTAP10-10 KRTAP10-7

3.31e-0339412PF13885
DomainLaminin_G_2

CRB1 CNTNAP2

3.48e-0340412PF02210
DomainLamG

CRB1 CNTNAP2

4.20e-0344412SM00282
DomainSushi

PAPPA VCAN

5.82e-0352412PF00084
DomainCCP

PAPPA VCAN

6.26e-0354412SM00032
PathwayREACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_TRANSPORT_AND_UPTAKE_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS

LAMB2 LAMC1 PAPPA FBN1 PLG TIMP1 VCAN

1.21e-08124337M27285
PathwayBIOCARTA_NOTCH_PATHWAY

ADAM17 DLL1 NOTCH1

2.33e-076333MM1584
PathwayBIOCARTA_NOTCH_PATHWAY

ADAM17 DLL1 NOTCH1

2.33e-076333M22074
PathwayREACTOME_SIGNALING_BY_NOTCH1_T_7_9_NOTCH1_M1580_K2555_TRANSLOCATION_MUTANT

ADAM17 DLL1 NOTCH1

4.06e-077333M27199
PathwayREACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS

DNER ADAM17 DLL1 NOTCH1

7.49e-0731334M592
PathwayBIOCARTA_PS1_PATHWAY

ADAM17 DLL1 NOTCH1

4.18e-0614333MM1459
PathwayBIOCARTA_PS1_PATHWAY

ADAM17 DLL1 NOTCH1

4.18e-0614333M16173
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

LAMB2 LAMC1 ADAM17 FBN1 PLG TIMP1 VCAN

4.90e-06300337M610
PathwayREACTOME_SIGNALING_BY_NOTCH1_HD_DOMAIN_MUTANTS_IN_CANCER

ADAM17 DLL1 NOTCH1

5.22e-0615333M27202
PathwayREACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX

LAMC1 ADAM17 FBN1 PLG TIMP1

1.71e-05140335M587
PathwayREACTOME_SIGNALING_BY_NOTCH1

DNER ADAM17 DLL1 NOTCH1

2.55e-0574334M616
PathwayWP_CANONICAL_AND_NONCANONICAL_NOTCH_SIGNALING

DNER DLL1 NOTCH1

3.29e-0527333M39545
PathwayKEGG_MEDICUS_REFERENCE_PLASMIN_MEDIATED_ACTIVATION_OF_LATENT_TGF_BETA

FBN1 PLG

1.47e-048332M47850
PathwayWP_NOTCH_SIGNALING_WP268

ADAM17 DLL1 NOTCH1

1.55e-0445333M39571
PathwayWP_NOTCH_SIGNALING_PATHWAY

ADAM17 DLL1 NOTCH1

1.66e-0446333MM15971
PathwayREACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_TRANSPORT_AND_UPTAKE_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS

PAPPA FBN1 TIMP1 VCAN

1.69e-04120334MM14982
PathwayKEGG_NOTCH_SIGNALING_PATHWAY

ADAM17 DLL1 NOTCH1

1.77e-0447333M7946
PathwayWP_SOMITOGENESIS_IN_THE_CONTEXT_OF_SPONDYLOCOSTAL_DYSOSTOSIS

DLL1 NOTCH1

1.89e-049332M39869
PathwayWP_GENE_REGULATORY_NETWORK_MODELLING_SOMITOGENESIS

DLL1 NOTCH1

2.36e-0410332MM15839
PathwayWP_VITAMIN_B12_METABOLISM

LRP2 PLG INSR

2.67e-0454333M39337
PathwayWP_GENE_REGULATORY_NETWORK_MODELING_SOMITOGENESIS

DLL1 NOTCH1

2.88e-0411332M39647
PathwayPID_INTEGRIN4_PATHWAY

LAMB2 LAMC1

2.88e-0411332M158
PathwayKEGG_MEDICUS_REFERENCE_NOTCH_PROTEOLYTIC_ACTIVATION

ADAM17 NOTCH1

2.88e-0411332M47865
PathwayREACTOME_SIGNALING_BY_NOTCH1_PEST_DOMAIN_MUTANTS_IN_CANCER

ADAM17 DLL1 NOTCH1

3.30e-0458333M29616
PathwayBIOCARTA_HES_PATHWAY

DLL1 NOTCH1

3.46e-0412332MM1562
PathwayBIOCARTA_HES_PATHWAY

DLL1 NOTCH1

3.46e-0412332M22042
PathwayPID_NOTCH_PATHWAY

DNER DLL1 NOTCH1

3.47e-0459333M17
PathwayWP_NOTCH_SIGNALING_WP61

ADAM17 DLL1 NOTCH1

3.83e-0461333M39540
PathwayWP_DYRK1A_INVOLVEMENT_REGARDING_CELL_PROLIFERATION_IN_BRAIN_DEVELOPMENT

DNER DLL1 NOTCH1

4.02e-0462333M45532
PathwayKEGG_MEDICUS_REFERENCE_NOTCH_SIGNALING_PATHWAY

DLL1 NOTCH1

4.08e-0413332M47423
PathwayPID_INTEGRIN1_PATHWAY

LAMB2 LAMC1 FBN1

4.84e-0466333M18
PathwayKEGG_MEDICUS_VARIANT_NOTCH_OVEREXPRESSION_TO_NOTCH_SIGNALING_PATHWAY

DLL1 NOTCH1

6.25e-0416332M47424
PathwayWP_NOTCH1_REGULATION_OF_ENDOTHELIAL_CELL_CALCIFICATION

DLL1 NOTCH1

7.07e-0417332M39389
PathwayREACTOME_ECM_PROTEOGLYCANS

LAMB2 LAMC1 VCAN

7.31e-0476333M27219
PathwayWP_DELTANOTCH_SIGNALING_PATHWAY

ADAM17 DLL1 NOTCH1

9.13e-0482333MM15922
PathwayWP_COMPLEMENT_SYSTEM

LRP2 LAMC1 PLG

1.44e-0396333M39581
PathwayREACTOME_MET_ACTIVATES_PTK2_SIGNALING

LAMB2 LAMC1

2.22e-0330332M27772
PathwayREACTOME_LAMININ_INTERACTIONS

LAMB2 LAMC1

2.22e-0330332M27216
PathwayWP_INFLAMMATORY_RESPONSE_PATHWAY

LAMB2 LAMC1

2.22e-0330332M39641
PathwayWP_INFLAMMATORY_RESPONSE_PATHWAY

LAMB2 LAMC1

2.22e-0330332MM15812
PathwayREACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX

FBN1 PLG TIMP1

2.35e-03114333MM14571
PathwayREACTOME_SIGNALING_BY_NOTCH

DNER ADAM17 DLL1 NOTCH1

2.49e-03246334M10189
PathwayWP_ALPHA_6_BETA_4_SIGNALING

LAMB2 LAMC1

2.68e-0333332M39503
PathwayREACTOME_ACTIVATION_OF_MATRIX_METALLOPROTEINASES

PLG TIMP1

2.68e-0333332M26976
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

FBN1 PLG TIMP1 VCAN

2.95e-03258334MM14572
PathwayKEGG_PRION_DISEASES

LAMC1 NOTCH1

3.01e-0335332M13036
PathwayREACTOME_ACTIVATION_OF_MATRIX_METALLOPROTEINASES

PLG TIMP1

3.54e-0338332MM14611
PathwayREACTOME_SIGNALING_BY_NOTCH

DLL1 NOTCH1

3.73e-0339332MM14604
PathwayREACTOME_MET_PROMOTES_CELL_MOTILITY

LAMB2 LAMC1

4.12e-0341332M27778
PathwayWP_MIRNA_TARGETS_IN_ECM_AND_MEMBRANE_RECEPTORS

LAMB2 LAMC1

4.52e-0343332M39565
PathwayPID_INTEGRIN3_PATHWAY

LAMC1 FBN1

4.52e-0343332M53
PathwayPID_A6B1_A6B4_INTEGRIN_PATHWAY

LAMB2 LAMC1

5.16e-0346332M239
PathwayPID_PS1_PATHWAY

DLL1 NOTCH1

5.16e-0346332M70
Pubmed

Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.

LAMB2 LAMC1 PAPPA ADAM17 FBN1 TIMP1 VCAN

3.10e-0824845724006456
Pubmed

Local anesthetics impair the growth and self-renewal of glioblastoma stem cells by inhibiting ZDHHC15-mediated GP130 palmitoylation.

LRP2 LAMC1 FBN1 CRB1 ZNF77

3.52e-087145533541421
Pubmed

Extracellular matrix signatures of human primary metastatic colon cancers and their metastases to liver.

LAMB2 LAMC1 FBN1 PLG MUC2 VCAN

4.64e-0815345625037231
Pubmed

The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.

LAMB2 LAMC1 FBN1 PLG MUC2 VCAN

7.81e-0816745622159717
Pubmed

Fringe glycosyltransferases differentially modulate Notch1 proteolysis induced by Delta1 and Jagged1.

ADAM17 DLL1 NOTCH1

1.69e-07945315574878
Pubmed

Expression of the type IV collagenase system during mouse kidney development and tubule segmentation.

LRP2 UMOD TIMP1

1.69e-07945311675412
Pubmed

Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics.

LAMB2 LAMC1 FBN1 PLG VCAN

8.82e-0713545528675934
Pubmed

Second-generation Notch1 activity-trap mouse line (N1IP::CreHI) provides a more comprehensive map of cells experiencing Notch1 activity.

UMOD DLL1 NOTCH1

9.11e-071545325725069
Pubmed

Interaction of human pregnancy-associated plasma protein-A with serine proteinases.

PAPPA PLG

1.64e-0624527586586
Pubmed

Cis-interactions between Notch and Delta generate mutually exclusive signalling states.

DLL1 NOTCH1

1.64e-06245220418862
Pubmed

Insulin receptor mutation results in insulin resistance and hyperinsulinemia but does not exacerbate Alzheimer's-like phenotypes in mice.

ZBTB20 INSR

1.64e-06245221549686
Pubmed

Zfp64 participates in Notch signaling and regulates differentiation in mesenchymal cells.

NOTCH1 ZFP64

1.64e-06245218430783
Pubmed

Versican interacts with fibrillin-1 and links extracellular microfibrils to other connective tissue networks.

FBN1 VCAN

1.64e-06245211726670
Pubmed

Alteration of Delta-like ligand 1 and Notch 1 receptor in various placental disorders with special reference to early onset preeclampsia.

DLL1 NOTCH1

1.64e-06245226014475
Pubmed

Dysregulation of the ADAM17/Notch signalling pathways in endometriosis: from oxidative stress to fibrosis.

ADAM17 NOTCH1

1.64e-06245228486700
Pubmed

ADAM17 regulates epidermal growth factor receptor expression through the activation of Notch1 in non-small cell lung cancer.

ADAM17 NOTCH1

1.64e-06245220551051
Pubmed

Notch1 endocytosis is induced by ligand and is required for signal transduction.

DLL1 NOTCH1

1.64e-06245226522918
Pubmed

Homotypic versican G1 domain interactions enhance hyaluronan incorporation into fibrillin microfibrils.

FBN1 VCAN

1.64e-06245223963449
Pubmed

Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain.

ADAM17 NOTCH1

1.64e-0624529620803
Pubmed

A novel proteolytic cleavage involved in Notch signaling: the role of the disintegrin-metalloprotease TACE.

ADAM17 NOTCH1

1.64e-06245210882063
Pubmed

Notch1 induces enhanced expression of Delta-like-1 in the U251MG glioma cell line.

DLL1 NOTCH1

1.64e-06245219724883
Pubmed

Epigenetic regulation of Delta-Like1 controls Notch1 activation in gastric cancer.

DLL1 NOTCH1

1.64e-06245222249198
Pubmed

A laminin-like adhesive protein concentrated in the synaptic cleft of the neuromuscular junction.

LAMB2 LAMC1

1.64e-0624522922051
Pubmed

NOTCH, a new signaling pathway implicated in holoprosencephaly.

DLL1 NOTCH1

1.64e-06245221196490
Pubmed

Combined Detection of Plasma Tumor Necrosis Factor-α Converting Enzyme and Notch1 is Valuable in Screening Endoleak After Endovascular Abdominal Aortic Aneurysms Repair.

ADAM17 NOTCH1

1.64e-06245233905845
Pubmed

Combining detection of Notch1 and tumor necrosis factor-α converting enzyme is a reliable biomarker for the diagnosis of abdominal aortic aneurysms.

ADAM17 NOTCH1

1.64e-06245225744398
Pubmed

Notch1 engagement by Delta-like-1 promotes differentiation of B lymphocytes to antibody-secreting cells.

DLL1 NOTCH1

1.64e-06245217878313
Pubmed

Spatiotemporal oscillations of Notch1, Dll1 and NICD are coordinated across the mouse PSM.

DLL1 NOTCH1

1.64e-06245225468943
Pubmed

Regulation of Notch1 signaling by Delta-like ligand 1 intracellular domain through physical interaction.

DLL1 NOTCH1

1.64e-06245221643850
Pubmed

A Disintegrin and Metalloproteinase Domain 17 Regulates Colorectal Cancer Stem Cells and Chemosensitivity Via Notch1 Signaling.

ADAM17 NOTCH1

1.64e-06245226744411
Pubmed

Generation of Distal Renal Segments Involves a Unique Population of Aqp2 + Progenitor Cells.

LRP2 UMOD NOTCH1

1.93e-061945334667084
Pubmed

Barx2 and Fgf10 regulate ocular glands branching morphogenesis by controlling extracellular matrix remodeling.

LAMB2 TIMP1 VCAN

2.27e-062045321750040
Pubmed

A novel gene family NBPF: intricate structure generated by gene duplications during primate evolution.

NBPF10 NBPF19 NBPF20

2.65e-062145316079250
Pubmed

FGF signaling expands embryonic cortical surface area by regulating Notch-dependent neurogenesis.

DLL1 NOTCH1 ZFPM2

3.06e-062245322031906
Pubmed

Ctip1 Regulates the Balance between Specification of Distinct Projection Neuron Subtypes in Deep Cortical Layers.

BCL11A STAB2 ZFPM2

3.06e-062245327117402
Pubmed

The ets-domain transcription factor Spdef promotes maturation of goblet and paneth cells in the intestinal epithelium.

CCL15 DLL1 MUC2

3.52e-062345319549527
Pubmed

GATA6 Regulates Aortic Valve Remodeling, and Its Haploinsufficiency Leads to Right-Left Type Bicuspid Aortic Valve.

FBN1 TIMP1 VCAN

3.52e-062345329567669
Pubmed

The COX-2 selective inhibitor-independent COX-2 effect on colon carcinoma cells is associated with the Delta1/Notch1 pathway.

DLL1 NOTCH1

4.91e-06345218320325
Pubmed

Activation of Notch signal pathway is associated with a poorer prognosis in acute myeloid leukemia.

DLL1 NOTCH1

4.91e-06345220812035
Pubmed

Delta-like 1-Lysine613 regulates notch signaling.

DLL1 NOTCH1

4.91e-06345221985982
Pubmed

The nephroblastoma overexpressed gene (NOV/ccn3) protein associates with Notch1 extracellular domain and inhibits myoblast differentiation via Notch signaling pathway.

DLL1 NOTCH1

4.91e-06345212050162
Pubmed

Both Notch1 and its ligands in B cells promote antibody production.

DLL1 NOTCH1

4.91e-06345228863329
Pubmed

Cancer stem cell and embryonic development-associated molecules contribute to prognostic significance in ovarian cancer.

DLL1 NOTCH1

4.91e-06345222080880
Pubmed

Control of vertebrate multiciliogenesis by miR-449 through direct repression of the Delta/Notch pathway.

DLL1 NOTCH1

4.91e-06345221602795
Pubmed

Verification of microRNA expression in human endometrial adenocarcinoma.

DLL1 NOTCH1

4.91e-06345227039384
Pubmed

Leukemia inhibitory factor increases the invasiveness of trophoblastic cells through integrated increase in the expression of adhesion molecules and pappalysin 1 with a concomitant decrease in the expression of tissue inhibitor of matrix metalloproteinases.

PAPPA TIMP1

4.91e-06345223122949
Pubmed

Expression of Notch-1 and its ligands, Delta-like-1 and Jagged-1, is critical for glioma cell survival and proliferation.

DLL1 NOTCH1

4.91e-06345215781650
Pubmed

Laminin-121--recombinant expression and interactions with integrins.

LAMB2 LAMC1

4.91e-06345220566382
Pubmed

Selective use of ADAM10 and ADAM17 in activation of Notch1 signaling.

ADAM17 NOTCH1

4.91e-06345219704010
Pubmed

Analysis of the Conditions That Affect the Selective Processing of Endogenous Notch1 by ADAM10 and ADAM17.

ADAM17 NOTCH1

4.91e-06345233673337
Pubmed

Lfng regulates the synchronized oscillation of the mouse segmentation clock via trans-repression of Notch signalling.

DLL1 NOTCH1

4.91e-06345223072809
Pubmed

Horizontal basal cells self-govern their neurogenic potential during injury-induced regeneration of the olfactory epithelium.

DLL1 NOTCH1

4.91e-06345237260223
Pubmed

Notch signaling confers antigen-presenting cell functions on mast cells.

DLL1 NOTCH1

4.91e-06345219130928
Pubmed

The intracellular region of Notch ligands Dll1 and Dll3 regulates their trafficking and signaling activity.

DLL1 NOTCH1

4.91e-06345218676613
Pubmed

Massive aggrecan and versican accumulation in thoracic aortic aneurysm and dissection.

FBN1 VCAN

4.91e-06345229515038
Pubmed

Human beta 2 chain of laminin (formerly S chain): cDNA cloning, chromosomal localization, and expression in carcinomas.

LAMB2 LAMC1

4.91e-0634527698745
Pubmed

Tissue inhibitor of metalloproteinase 3 deficiency causes hepatic steatosis and adipose tissue inflammation in mice.

ADAM17 INSR

4.91e-06345219027012
Pubmed

Laminin-11.

LAMB2 LAMC1

4.91e-06345210481268
Pubmed

Sequencing of laminin B chain cDNAs reveals C-terminal regions of coiled-coil alpha-helix.

LAMB2 LAMC1

4.91e-0634526209134
Pubmed

Intrinsic selectivity of Notch 1 for Delta-like 4 over Delta-like 1.

DLL1 NOTCH1

4.91e-06345223839946
Pubmed

Differential genetic diagnoses of adult post-lingual hearing loss according to the audiogram pattern and novel candidate gene evaluation.

DLL1 NOTCH1

4.91e-06345234519870
Pubmed

Large-Scale Human Dendritic Cell Differentiation Revealing Notch-Dependent Lineage Bifurcation and Heterogeneity.

DLL1 NOTCH1

4.91e-06345230110645
Pubmed

Dose-dependent effects of the Notch ligand Delta1 on ex vivo differentiation and in vivo marrow repopulating ability of cord blood cells.

DLL1 NOTCH1

4.91e-06345215976178
Pubmed

Adamts18 modulates the development of the aortic arch and common carotid artery.

LAMC1 FBN1 VCAN

5.15e-062645334189436
Pubmed

Transcription factors expressed in olfactory bulb local progenitor cells revealed by genome-wide transcriptome profiling.

BCL11A ZBTB20 NSD2 NOTCH1

6.02e-069145421194568
Pubmed

Protein interactome reveals converging molecular pathways among autism disorders.

LAMB2 LAMC1 BCL11A FBN1 HECW1 NOTCH1 ZFPM2

7.22e-0656045721653829
Pubmed

Glycoproteomics Reveals Decorin Peptides With Anti-Myostatin Activity in Human Atrial Fibrillation.

LAMB2 LAMC1 FBN1 VCAN

7.76e-069745427559042
Pubmed

Proteomics characterization of extracellular space components in the human aorta.

LAMB2 LAMC1 FBN1 VCAN

9.11e-0610145420551380
Pubmed

Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins.

LRP2 FCRL5 NOTCH1 INSR

9.11e-0610145423382219
Pubmed

Delta-like 4 is the essential, nonredundant ligand for Notch1 during thymic T cell lineage commitment.

DLL1 NOTCH1

9.81e-06445218824585
Pubmed

Notch signalling pathway mediates hair cell development in mammalian cochlea.

DLL1 NOTCH1

9.81e-06445210080181
Pubmed

Differential regulation of osteoclastogenesis by Notch2/Delta-like 1 and Notch1/Jagged1 axes.

DLL1 NOTCH1

9.81e-06445222390640
Pubmed

Intracellular cleavage of Notch leads to a heterodimeric receptor on the plasma membrane.

DLL1 NOTCH1

9.81e-0644529244302
Pubmed

Delta-like1-induced Notch1 signaling regulates the human plasmacytoid dendritic cell versus T-cell lineage decision through control of GATA-3 and Spi-B.

DLL1 NOTCH1

9.81e-06445216317090
Pubmed

Attenuation of Notch signalling by the Down-syndrome-associated kinase DYRK1A.

DLL1 NOTCH1

9.81e-06445219383720
Pubmed

The Notch signalling pathway in hair growth.

DLL1 NOTCH1

9.81e-0644529858728
Pubmed

Analysis of HeyL expression in wild-type and Notch pathway mutant mouse embryos.

DLL1 NOTCH1

9.81e-06445211044625
Pubmed

ADAM10-Dependent Signaling Through Notch1 and Notch4 Controls Development of Organ-Specific Vascular Beds.

ADAM17 NOTCH1

9.81e-06445227354212
Pubmed

Laminins 411 and 421 differentially promote tumor cell migration via α6β1 integrin and MCAM (CD146).

LAMB2 LAMC1

9.81e-06445224951930
Pubmed

Timp3 deficiency in insulin receptor-haploinsufficient mice promotes diabetes and vascular inflammation via increased TNF-alpha.

ADAM17 INSR

9.81e-06445216294222
Pubmed

Isolation and functional analysis of a cDNA for human Jagged2, a gene encoding a ligand for the Notch1 receptor.

DLL1 NOTCH1

9.81e-0644529315665
Pubmed

Canonical Notch ligands and Fringes have distinct effects on NOTCH1 and NOTCH2.

DLL1 NOTCH1

9.81e-06445232820046
Pubmed

No evidence for a functional role of bi-directional Notch signaling during angiogenesis.

DLL1 NOTCH1

9.81e-06445223300864
Pubmed

DLL1-mediated Notch activation regulates endothelial identity in mouse fetal arteries.

DLL1 NOTCH1

9.81e-06445219144989
Pubmed

Regulation and Function of Laminin A5 during Mouse and Human Decidualization.

LAMB2 LAMC1

9.81e-06445235008625
Pubmed

Different downstream pathways for Notch signaling are required for gliogenic and chondrogenic specification of mouse mesencephalic neural crest cells.

DLL1 NOTCH1

9.81e-06445218299190
Pubmed

Notch controls the survival of memory CD4+ T cells by regulating glucose uptake.

DLL1 NOTCH1

9.81e-06445225501905
Pubmed

Role of recycling, Mindbomb1 association, and exclusion from lipid rafts of δ-like 4 for effective Notch signaling to drive T cell development.

DLL1 NOTCH1

9.81e-06445223162128
Pubmed

Epidermal ADAM17 is dispensable for notch activation.

ADAM17 NOTCH1

9.81e-06445223657465
Pubmed

Changes in laminin isoforms associated with brain tumor invasion and angiogenesis.

LAMB2 LAMC1

9.81e-06445216146715
Pubmed

Laminin chain assembly. Specific sequences at the C terminus of the long arm are required for the formation of specific double- and triple-stranded coiled-coil structures.

LAMB2 LAMC1

9.81e-0644528034675
Pubmed

The renal glomerulus of mice lacking s-laminin/laminin beta 2: nephrosis despite molecular compensation by laminin beta 1.

LAMB2 LAMC1

1.63e-0554527670489
Pubmed

Deletion of Notch1 converts pro-T cells to dendritic cells and promotes thymic B cells by cell-extrinsic and cell-intrinsic mechanisms.

DLL1 NOTCH1

1.63e-05545219110448
Pubmed

Immunohistochemical expression of Notch signaling in the lining epithelium of periapical cysts.

DLL1 NOTCH1

1.63e-05545221238798
Pubmed

The disintegrin/metalloprotease ADAM 10 is essential for Notch signalling but not for alpha-secretase activity in fibroblasts.

DLL1 NOTCH1

1.63e-05545212354787
Pubmed

Soluble M6P/IGF2R released by TACE controls angiogenesis via blocking plasminogen activation.

ADAM17 PLG

1.63e-05545221273553
Pubmed

The notch receptor and its ligands are selectively expressed during hematopoietic development in the mouse.

DLL1 NOTCH1

1.63e-05545211713346
Pubmed

Botch promotes neurogenesis by antagonizing Notch.

DLL1 NOTCH1

1.63e-05545222445366
Pubmed

Notch1 and its ligands Delta-like and Jagged are expressed and active in distinct cell populations in the postnatal mouse brain.

DLL1 NOTCH1

1.63e-05545212175503
Pubmed

Nrf2 Transcriptional Activity Governs Intestine Development.

MUC2 NOTCH1

1.63e-05545235682851
InteractionFBXO2 interactions

LRP2 LAMB2 LAMC1 ADAM17 TM2D3 FBN1 TIMP1 NOTCH1 INSR

2.11e-07411449int:FBXO2
InteractionIGFL3 interactions

LRP2 LAMB2 TM2D3 NOTCH1 INSR

6.05e-0775445int:IGFL3
InteractionNCR3 interactions

LAMB2 LAMC1 ADAM17 TIMP1 VCAN

6.21e-06120445int:NCR3
InteractionTAFA4 interactions

LRP2 LAMC1 VCAN INSR

6.21e-0655444int:TAFA4
InteractionITGB4 interactions

NBPF19 LAMB2 LAMC1 KRTAP10-7 KRT40

7.58e-06125445int:ITGB4
InteractionZDHHC15 interactions

LRP2 LAMC1 FBN1 CRB1 ZNF77

7.58e-06125445int:ZDHHC15
InteractionTAPBPL interactions

NBPF19 KRTAP10-7 KRT40

9.18e-0619443int:TAPBPL
InteractionHOXA1 interactions

NBPF19 LAMB2 FBN1 KRTAP10-10 NOTCH1 KRTAP10-7 KRT40

1.11e-05356447int:HOXA1
InteractionZNF408 interactions

LRP2 NBPF19 FBN1 KRTAP10-7 KRT40

1.56e-05145445int:ZNF408
InteractionNTN5 interactions

LRP2 FBN1 NOTCH1

1.90e-0524443int:NTN5
InteractionSLC23A1 interactions

NBPF19 KRTAP10-7 KRT40

2.44e-0526443int:SLC23A1
InteractionZNF580 interactions

NBPF19 KRTAP10-7 KRT40

4.61e-0532443int:ZNF580
InteractionZNF697 interactions

ZBTB20 KRTAP10-7 KRT40

5.06e-0533443int:ZNF697
InteractionSDF2L1 interactions

LAMB2 LAMC1 ADAM17 TIMP1 VCAN INSR

6.72e-05322446int:SDF2L1
InteractionLY86 interactions

LAMB2 LAMC1 TIMP1 VCAN INSR

1.07e-04217445int:LY86
InteractionBRME1 interactions

NBPF19 KRTAP10-7 KRT40

1.21e-0444443int:BRME1
InteractionDNER interactions

DNER NOTCH1

1.29e-048442int:DNER
InteractionAEN interactions

KRTAP10-7 ZFP64 KRT40

1.47e-0447443int:AEN
InteractionWNT3A interactions

LAMC1 NOTCH1 INSR

1.67e-0449443int:WNT3A
InteractionGGH interactions

LAMB2 LAMC1 TIMP1 VCAN INSR

1.81e-04243445int:GGH
InteractionCCDC26 interactions

KRTAP10-7 KRT40

2.07e-0410442int:CCDC26
InteractionZNF587 interactions

NBPF19 KRTAP10-10 KRTAP10-7 KRT40

2.12e-04135444int:ZNF587
InteractionHBZ interactions

NBPF19 KRTAP10-7 KRT40

2.23e-0454443int:HBZ
InteractionMXI1 interactions

NBPF19 KRTAP10-7 KRT40

2.35e-0455443int:MXI1
InteractionMYPOP interactions

NBPF19 KRTAP10-7 KRT40

2.35e-0455443int:MYPOP
InteractionPOM121L8P interactions

KRTAP10-7 KRT40

2.53e-0411442int:POM121L8P
InteractionZFP41 interactions

LRP2 FBN1 KRTAP10-7

2.62e-0457443int:ZFP41
InteractionSLURP1 interactions

LAMB2 LAMC1 VCAN INSR

2.72e-04144444int:SLURP1
InteractionINSL5 interactions

LAMB2 ADAM17 INSR

2.76e-0458443int:INSL5
InteractionWDR25 interactions

NBPF19 LAMC1 KRT40

2.76e-0458443int:WDR25
InteractionZNF124 interactions

NBPF19 KRTAP10-7 KRT40

2.90e-0459443int:ZNF124
InteractionCTSZ interactions

NBPF19 KRTAP10-10 KRT40

2.90e-0459443int:CTSZ
InteractionITGB5 interactions

NBPF19 STAB2 KRTAP10-7 KRT40

2.94e-04147444int:ITGB5
InteractionGLIDR interactions

KRTAP10-7 KRT40

3.03e-0412442int:GLIDR
InteractionLCE3E interactions

NBPF19 KRTAP10-7 KRT40

3.05e-0460443int:LCE3E
InteractionSPATA24 interactions

NBPF19 KRTAP10-7 KRT40

3.05e-0460443int:SPATA24
InteractionFAM27E3 interactions

KRTAP10-7 KRT40

3.58e-0413442int:FAM27E3
InteractionPRG2 interactions

LAMB2 LAMC1 PAPPA NOTCH1 VCAN

3.78e-04285445int:PRG2
InteractionZBTB24 interactions

BCL11A ZBTB3 KRTAP10-7 KRT40

3.96e-04159444int:ZBTB24
InteractionFBLN2 interactions

FBN1 VCAN ZNF77

4.04e-0466443int:FBLN2
InteractionPHLDA1 interactions

NBPF19 KRTAP10-7 KRT40

4.04e-0466443int:PHLDA1
InteractionDOCK2 interactions

NBPF19 KRTAP10-7 KRT40

4.04e-0466443int:DOCK2
InteractionZNF26 interactions

KRTAP10-7 KRT40

4.17e-0414442int:ZNF26
InteractionZNF844 interactions

KRTAP10-7 KRT40

4.17e-0414442int:ZNF844
InteractionRTN4RL1 interactions

NBPF19 KRTAP10-7

4.17e-0414442int:RTN4RL1
InteractionLCE3C interactions

NBPF19 KRTAP10-10 KRTAP10-7

4.22e-0467443int:LCE3C
InteractionLCE1E interactions

NBPF19 KRTAP10-10 KRTAP10-7

4.41e-0468443int:LCE1E
InteractionKRT83 interactions

NBPF19 KRTAP10-7 KRT40

4.41e-0468443int:KRT83
InteractionCREB5 interactions

NBPF19 KRTAP10-10 KRTAP10-7 KRT40

4.45e-04164444int:CREB5
InteractionMBD3L1 interactions

BCL11A ZBTB20 ZNF77

4.80e-0470443int:MBD3L1
InteractionZNF266 interactions

KRTAP10-7 KRT40

4.80e-0415442int:ZNF266
InteractionZNF625 interactions

KRTAP10-7 KRT40

4.80e-0415442int:ZNF625
InteractionCHIC2 interactions

NBPF19 KRTAP10-7 KRT40

5.43e-0473443int:CHIC2
InteractionCCER1 interactions

NBPF19 KRT40

5.48e-0416442int:CCER1
InteractionMAPKBP1 interactions

NBPF19 KRTAP10-7 KRT40

5.65e-0474443int:MAPKBP1
InteractionCST11 interactions

LAMB2 ZBTB20 TIMP1

5.88e-0475443int:CST11
InteractionZNF337 interactions

KRTAP10-7 KRT40

6.21e-0417442int:ZNF337
InteractionCATIP interactions

KRTAP10-7 KRT40

6.21e-0417442int:CATIP
InteractionZNF707 interactions

HECW1 NOTCH1 KRTAP10-7

6.84e-0479443int:ZNF707
InteractionKRTAP4-4 interactions

NBPF19 KRTAP10-10 KRTAP10-7

7.36e-0481443int:KRTAP4-4
InteractionZNF138 interactions

KRTAP10-7 KRT40

7.78e-0419442int:ZNF138
InteractionLCE1B interactions

NBPF19 KRTAP10-10 KRTAP10-7

8.46e-0485443int:LCE1B
InteractionNPBWR2 interactions

KRTAP10-7 KRT40

8.63e-0420442int:NPBWR2
InteractionDMRT3 interactions

NBPF19 KRTAP10-7 KRT40

9.06e-0487443int:DMRT3
InteractionLCE2C interactions

NBPF19 KRTAP10-10 KRTAP10-7

9.36e-0488443int:LCE2C
InteractionZNF786 interactions

NBPF19 KRTAP10-7

9.53e-0421442int:ZNF786
InteractionGARIN6 interactions

NBPF19 KRT40

9.53e-0421442int:GARIN6
InteractionZNF543 interactions

ZNF543 KRTAP10-7

9.53e-0421442int:ZNF543
InteractionANKRD36BP1 interactions

KRTAP10-7 KRT40

9.53e-0421442int:ANKRD36BP1
InteractionCXCL16 interactions

LRP2 NBPF19 KRTAP10-7

9.67e-0489443int:CXCL16
InteractionPAPPA interactions

PAPPA PLG

1.05e-0322442int:PAPPA
InteractionLCE1F interactions

NBPF19 KRTAP10-10 KRTAP10-7

1.06e-0392443int:LCE1F
InteractionRLN1 interactions

LAMB2 ADAM17 INSR

1.10e-0393443int:RLN1
InteractionCHRD interactions

NBPF19 TM2D3 KRTAP10-7

1.13e-0394443int:CHRD
InteractionKRTAP5-6 interactions

NBPF19 KRTAP10-10 KRTAP10-7

1.13e-0394443int:KRTAP5-6
InteractionIL10 interactions

LRP2 NBPF19

1.14e-0323442int:IL10
InteractionMOBP interactions

KRTAP10-7 KRT40

1.14e-0323442int:MOBP
InteractionCHRNG interactions

NBPF19 KRTAP10-7

1.14e-0323442int:CHRNG
InteractionNTN4 interactions

NBPF19 LAMC1

1.14e-0323442int:NTN4
InteractionADAMTS1 interactions

VCAN KRT40 INSR

1.17e-0395443int:ADAMTS1
InteractionTSHR interactions

LAMB2 LAMC1 TIMP1

1.20e-0396443int:TSHR
InteractionSHFL interactions

NBPF19 KRTAP10-7 KRT40

1.24e-0397443int:SHFL
InteractionKLHL38 interactions

NBPF19 KRTAP10-7 KRT40

1.32e-0399443int:KLHL38
InteractionGNE interactions

NBPF19 KRTAP10-7 KRT40

1.52e-03104443int:GNE
InteractionZNF319 interactions

NBPF19 KRT40

1.58e-0327442int:ZNF319
InteractionKRTAP10-10 interactions

NBPF19 KRTAP10-10

1.58e-0327442int:KRTAP10-10
InteractionZNF439 interactions

KRTAP10-7 KRT40

1.58e-0327442int:ZNF439
InteractionMFNG interactions

DLL1 NOTCH1

1.58e-0327442int:MFNG
InteractionZNF575 interactions

KRTAP10-7 KRT40

1.58e-0327442int:ZNF575
InteractionTNFAIP6 interactions

LRP2 VCAN

1.58e-0327442int:TNFAIP6
InteractionFAM74A4 interactions

KRTAP10-7 KRT40

1.58e-0327442int:FAM74A4
InteractionFEZF1 interactions

LRP2 KRT40

1.70e-0328442int:FEZF1
InteractionLIMS2 interactions

KRTAP10-7 KRT40

1.70e-0328442int:LIMS2
GeneFamilyNeuroblastoma breakpoint family

NBPF10 NBPF19 NBPF20

9.57e-0623333662
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

BCL11A ZBTB20 ZNF543 ZBTB3 ZNF691 ZFPM2 ZFP64 ZNF77

3.42e-0571833828
GeneFamilyLaminin subunits

LAMB2 LAMC1

2.11e-0412332626
GeneFamilyHyalectan proteoglycans|V-set domain containing|Sushi domain containing|C-type lectin domain containing

PAPPA VCAN

4.84e-03573321179
CoexpressionNABA_MATRISOME

LAMB2 LAMC1 PAPPA ADAM17 CCL15 FBN1 PLG TIMP1 MUC2 ECM2 EGFEM1P VCAN OTOG

8.67e-0910084513MM17056
CoexpressionNABA_MATRISOME

LAMB2 LAMC1 PAPPA ADAM17 CCL15 FBN1 PLG TIMP1 MUC2 ECM2 VCAN OTOG

1.06e-0710264512M5889
CoexpressionNABA_CORE_MATRISOME

LAMB2 LAMC1 FBN1 ECM2 EGFEM1P VCAN OTOG

3.70e-07270457MM17057
CoexpressionNABA_ECM_GLYCOPROTEINS

LAMB2 LAMC1 FBN1 ECM2 EGFEM1P OTOG

8.90e-07191456MM17059
CoexpressionNABA_CORE_MATRISOME

LAMB2 LAMC1 FBN1 ECM2 VCAN OTOG

7.30e-06275456M5884
CoexpressionNABA_ECM_GLYCOPROTEINS

LAMB2 LAMC1 FBN1 ECM2 OTOG

2.13e-05196455M3008
CoexpressionHALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION

LAMC1 FBN1 TIMP1 ECM2 VCAN

2.35e-05200455M5930
CoexpressionCLASPER_LYMPHATIC_VESSELS_DURING_METASTASIS_DN

FBN1 TIMP1 VCAN

2.98e-0535453M11788
CoexpressionCLASPER_LYMPHATIC_VESSELS_DURING_METASTASIS_DN

FBN1 TIMP1 VCAN

3.24e-0536453MM1212
CoexpressionHEBERT_MATRISOME_TNBC_LUNG_METASTASIS_TUMOR_CELL_DERIVED

LAMB2 LAMC1

4.30e-056452M48000
CoexpressionHALLMARK_WNT_BETA_CATENIN_SIGNALING

ADAM17 DLL1 NOTCH1

5.18e-0542453M5895
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HGABA

DNER PAPPA BCL11A RAPGEF6 MUC2 VCAN ZFPM2 ZNF77 CNTNAP2

9.23e-051106459M39071
CoexpressionAIZARANI_LIVER_C13_LSECS_2

LAMB2 STAB2 DLL1 TIMP1 INSR

1.22e-04283455M39117
CoexpressionRUBENSTEIN_SKELETAL_MUSCLE_FBN1_FAP_CELLS

NBPF10 LAMB2 FBN1 TIMP1 VCAN

1.34e-04289455M41750
CoexpressionDESCARTES_FETAL_PANCREAS_ENS_NEURONS

DNER HECW1 SLCO6A1 CNTNAP2

1.84e-04165454M40270
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_500_k-means-cluster#3

BCL11A ZBTB20 DLL1 CNTNAP2

7.10e-05118404Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_500_K3
CoexpressionAtlaskidney_P4_CapMesRenVes_Crym_top-relative-expression-ranked_1000

LRP2 LAMC1 FBN1 ZBTB20 DLL1 NSD2 NOTCH1 VCAN

8.90e-05783408gudmap_kidney_P4_CapMesRenVes_Crym_1000
CoexpressionAtlaskidney_P4_CapMesRenVes_Crym_top-relative-expression-ranked_500

LRP2 LAMC1 ZBTB20 DLL1 NOTCH1 VCAN

9.35e-05398406gudmap_kidney_P4_CapMesRenVes_Crym_500
CoexpressionAtlasStromal Cells, Fi.Sk, gp38+ CD140a+, Skin, avg-4

LAMB2 LAMC1 FBN1 TIMP1 ECM2 VCAN

1.56e-04437406GSM777046_500
CoexpressionAtlasStromal Cells, Fi.MTS15+.Th, CD45- PDGFRa+ MTS15+, Thymus, avg-3

LAMB2 LAMC1 FBN1 ZBTB20 ECM2 VCAN

1.72e-04445406GSM777043_500
CoexpressionAtlasDevelopingLowerUrinaryTract_P1_bladder_J_emap-30374_k-means-cluster#1_top-relative-expression-ranked_1000

DNER LAMC1 ZBTB20 INSR

1.75e-04149404gudmap_developingLowerUrinaryTract_P1_bladder_J_1000_k1
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_2500_k-means-cluster#3

LAMB2 CACNA1H ZBTB20 DLL1 INSR CNTNAP2

1.76e-04447406Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_2500_K3
ToppCell3'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PAPPA FBN1 TIMP1 SLCO6A1 ECM2 VCAN ZFPM2

1.17e-091994579846d6a31635fde759d55674631c11ab9270a603
ToppCelldroplet-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP2 PAPPA FBN1 ECM2 VCAN ZFPM2

3.39e-081874564e553721fa5598cb211f44e3226280b7e6885484
ToppCelldroplet-Pancreas-Exocrine-18m-Mesenchymal|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP2 PAPPA FBN1 ECM2 VCAN ZFPM2

3.39e-08187456d36e7fc6125e7a4310499365022d38f34b757a73
ToppCelldroplet-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP2 PAPPA FBN1 ECM2 VCAN ZFPM2

3.39e-08187456827eae63fabf6892a82ce7779b5f395958d3d628
ToppCellfacs-Lung-nan-3m-Mesenchymal-Adventitial_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNER LAMC1 FBN1 TIMP1 ECM2 VCAN

3.96e-08192456a2c31390da4962bda9a936470b0b68fa1f5d47d1
ToppCellfacs-Lung-nan-3m-Mesenchymal-adventitial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNER LAMC1 FBN1 TIMP1 ECM2 VCAN

3.96e-08192456eeab1cef7c36ae824381952c5b2c982368c379fd
ToppCelldroplet-Lung-immune-endo-depleted-3m-Mesenchymal-adventitial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNER LAMB2 LAMC1 FBN1 TIMP1 ECM2

4.08e-08193456858a186804b36d45957238d3d3eed2768b961641
ToppCelldroplet-Lung-immune-endo-depleted-3m-Mesenchymal-Adventitial_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNER LAMB2 LAMC1 FBN1 TIMP1 ECM2

4.08e-081934567865e7ec0a288249540d4cba94ae01c93e1b617c
ToppCellfacs-GAT-Fat-3m-Mesenchymal-mesenchymal_progenitor|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMB2 LAMC1 FBN1 ZBTB20 ECM2 VCAN

4.34e-0819545669a29d03e664b72f32d41876510c62345c3aed31
ToppCellfacs-GAT-Fat-3m-Mesenchymal|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMB2 LAMC1 FBN1 ZBTB20 ECM2 VCAN

4.34e-081954561cffae2b08dbfa1c633ce24023e89b66d28b5431
ToppCellfacs-GAT-Fat-3m-Mesenchymal-mesenchymal_stem_cell_of_adipose|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMB2 LAMC1 FBN1 ZBTB20 ECM2 VCAN

4.34e-081954569cef6f18664518060af7c192310dddce6d70345a
ToppCell3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PAPPA FBN1 TIMP1 SLCO6A1 ECM2 ZFPM2

4.61e-081974566b6440f1baad5680cf9e13ca3ab72a2c65523d59
ToppCellCOVID-19-Fibroblasts|COVID-19 / group, cell type (main and fine annotations)

LAMC1 PAPPA FBN1 TIMP1 VCAN ZFPM2

4.61e-08197456fb847f2277609c31fffcdf49517243ce0684facf
ToppCellPBMC-Control-Lymphocyte-B-B_cell-B_naive-B_naive-1|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

NBPF10 LAMC1 BCL11A FCRL5 CNTNAP2

9.31e-07176455ad05dd934f4ac2e656b3455de091f4c8772de6c8
ToppCellP15-Mesenchymal-mesenchymal_fibroblast-mesenchymal_alveolar_niche_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

DNER FBN1 TIMP1 ECM2 VCAN

1.10e-06182455e9fcae9d03a6faf85b91882c5da699037bc61aeb
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DNER LAMC1 PAPPA FBN1 VCAN

1.10e-061824553dfa9187e9d2bab1d199079d29209c4648220ada
ToppCelldroplet-Heart-4Chambers-18m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMC1 FBN1 TIMP1 ECM2 VCAN

1.10e-06182455f4b74c2756989812abe4e7055ec8918f69d56025
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LRP2 PAPPA PLG HECW1 INSR

1.13e-0618345584b64cf728629c3af9a8d2ed15b93adf562c54b8
ToppCell5'-GW_trimst-2-LymphNode-Mesenchymal-fibroblastic-Stromal_3_(C7+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PAPPA FBN1 ECM2 VCAN ZFPM2

1.16e-061844554d4d8f3f44c67d74c57e7af7b7c158f0157b2f49
ToppCellCOVID-19-kidney-Mito-rich_PCT|COVID-19 / Disease (COVID-19 only), tissue and cell type

LRP2 PAPPA PLG HECW1 INSR

1.19e-061854551bbc2ba8a20f72f61981b1301cdd6018cdd9150d
ToppCelldroplet-Heart-4Chambers-18m-Mesenchymal-fibroblast|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMC1 FBN1 TIMP1 ECM2 VCAN

1.22e-0618645535c88cc4eb388811fcac4323b549e5897fa8dc27
ToppCelldroplet-Heart-4Chambers-18m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMC1 FBN1 TIMP1 ECM2 VCAN

1.22e-06186455d998c5b00083cf2a7cd5341a98b7374b4de73c63
ToppCellCOVID-19-kidney-Mito-rich_PCT|kidney / Disease (COVID-19 only), tissue and cell type

LRP2 PAPPA PLG HECW1 INSR

1.26e-06187455738ec2611b4be6a08eedad16b57fba84e1f11fef
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LRP2 PAPPA PLG HECW1 INSR

1.32e-06189455204ab61ae606b2d9be0cb6bf6a83a011740693a8
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LRP2 PAPPA PLG HECW1 INSR

1.32e-0618945513fd07cc408a9486f61a7b2c3a132c52d14b438d
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_2_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

PAPPA FBN1 TIMP1 VCAN CDC7

1.36e-061904550fea33f2dc1efa23aaa2da1c318482a52a313ff1
ToppCellPND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DNER PAPPA FBN1 ECM2 VCAN

1.39e-061914559f478f36a0b895e607e3bb77fa0f9f03cc0f33fc
ToppCellLV-02._Fibroblast_II|World / Chamber and Cluster_Paper

LAMC1 FBN1 ZBTB20 TIMP1 VCAN

1.39e-06191455d36565257ccba8c1bbed2c1c01be66a9cbb5f834
ToppCelldroplet-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DNER LAMB2 FBN1 TIMP1 VCAN

1.43e-061924550e7e55505bd5454d7cf952a63fdcb46ec76f1973
ToppCellfacs-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l1|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LAMC1 FBN1 TIMP1 ECM2 VCAN

1.43e-061924557b48df661f61ce494bf6f0b9a74b0422e29c24bf
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMB2 LAMC1 FBN1 ECM2 VCAN

1.43e-06192455beac6b3c191b11add8e39e8d04562b478ea8929e
ToppCellfacs-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LAMC1 FBN1 TIMP1 ECM2 VCAN

1.43e-0619245532acd89617934016cd135d2cc797e8e79ae1b37f
ToppCellfacs-Lung-nan-3m-Mesenchymal|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMC1 FBN1 TIMP1 ECM2 VCAN

1.47e-06193455d9c20a092b507c43fcf7ccb04073fecd27d1749c
ToppCelldroplet-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l1|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DNER LAMB2 FBN1 TIMP1 VCAN

1.47e-06193455025836c5c5a711e477c326559e618e47cae42d11
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

DNER LAMC1 PAPPA FBN1 ZFPM2

1.47e-06193455261cafc167c86ab277be4ea7f08b0173e2dde26e
ToppCelldroplet-Limb_Muscle-nan-18m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMB2 LAMC1 FBN1 TIMP1 VCAN

1.47e-0619345545b5cab4dfeb0ed3b13631db5963740a792b810f
ToppCellControl-Fibroblasts-Intermediate_pathological_FB|Control / group, cell type (main and fine annotations)

PAPPA FBN1 TIMP1 VCAN ZFPM2

1.50e-0619445503a269f75a481ea54aea8e6444605db8d6df493d
ToppCellLV-02._Fibroblast_II|LV / Chamber and Cluster_Paper

LAMC1 PAPPA FBN1 TIMP1 VCAN

1.50e-06194455014d2feb5db2a6a35ef759761a41e466e108c3c1
ToppCellCOVID-19-Heart-Fib_2|Heart / Disease (COVID-19 only), tissue and cell type

LAMC1 PAPPA FBN1 TIMP1 VCAN

1.50e-06194455d91c9f2ec47319051fc398320693fddbe8bbd4d6
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LAMC1 FBN1 ECM2 VCAN ZFPM2

1.54e-06195455f54bc4454270ff06e85596f98199372b50d0179f
ToppCellRA-02._Fibroblast_II|RA / Chamber and Cluster_Paper

LAMC1 PAPPA FBN1 VCAN ZFPM2

1.54e-061954556a02ebbeb3199447ddce64d92d8809436e040eba
ToppCell3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PAPPA FBN1 TIMP1 ECM2 VCAN

1.54e-0619545551db90e7611f7d69980878c046505ff34212079b
ToppCellfacs-Lung-nan|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMB2 LAMC1 FBN1 ECM2 VCAN

1.58e-06196455b05f77f3990b662682ffeaf0e4c2fb190e0a6e65
ToppCellfacs-Lung-nan-3m|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMB2 LAMC1 FBN1 ECM2 VCAN

1.58e-06196455787c6cd92035e0b1108c2c086c42a229016e476b
ToppCellRA-02._Fibroblast_II|World / Chamber and Cluster_Paper

LAMC1 PAPPA FBN1 TIMP1 VCAN

1.58e-06196455e8cbda03837f1f26470a9d93aa7fdaa04e08e38a
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PAPPA FBN1 TIMP1 VCAN ZFPM2

1.66e-061984559541d68a1a6247dbd7161a62644eea6527c2c8ff
ToppCellfacs-Trachea-nan-3m-Mesenchymal-fibroblast|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMC1 FBN1 ZBTB20 ECM2 VCAN

1.66e-061984550dc7d59a07428a7b7e8bdc81f0e2417dd4ce3cf2
ToppCellCOVID-19-lung-Fibroblast|lung / Disease (COVID-19 only), tissue and cell type

LAMC1 PAPPA FBN1 TIMP1 VCAN

1.66e-06198455df3de77216f5c5d6141ec44d01c56b942f611838
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal-fibroblastic|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LAMC1 FBN1 DLL1 TIMP1 VCAN

1.70e-0619945530ab0750d51f168b18c434c974d24a4e70f29cc7
ToppCellFibroblasts|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

LAMB2 LAMC1 FBN1 ECM2 VCAN

1.70e-0619945540de6d4a31cf22efa2864f79e4ec8e2b7bfc9d4a
ToppCellFibroblasts-CD34+_Fibroblasts|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

LAMB2 LAMC1 FBN1 ECM2 VCAN

1.70e-0619945513ff7409e200a0b46cdb7924d15ef33639693622
ToppCelldistal-3-mesenchymal-Myofibroblast|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PAPPA FBN1 HECW1 ECM2 VCAN

1.70e-061994551f20addc0d138fec02ed6ca4c518169c568de263
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LAMC1 FBN1 DLL1 TIMP1 VCAN

1.70e-06199455e78f661b40da34768469549b6e755d330be6bbd8
ToppCelldistal-mesenchymal-Myofibroblast-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PAPPA FBN1 HECW1 ECM2 VCAN

1.75e-06200455069c8949b33ecfdb6da32992002d4060ff6082bc
ToppCell5'-Adult-SmallIntestine-Mesenchymal|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LAMC1 FBN1 TIMP1 ECM2 VCAN

1.75e-06200455a637281d91e95734ee4f8510b3780e0272b16fda
ToppCell5'-Adult-SmallIntestine-Mesenchymal-fibroblastic-Transitional_Stromal_3_(C3+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LAMC1 FBN1 TIMP1 ECM2 VCAN

1.75e-062004556f7f015b5fa1f52374f2c7d9ba339012395eda5f
ToppCellcellseq2-Mesenchymal-Fibroblastic-Fibroblastic_1-AF2|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

LAMC1 PAPPA FBN1 TIMP1 VCAN

1.75e-0620045544317fbf4d1480a37b50ab2777bf1a3e4fc0c05f
ToppCellTracheal-NucSeq-Stromal-Fibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

LAMC1 FBN1 ECM2 VCAN ZFPM2

1.75e-06200455b4ccffdd79526c85e5273d27b668dbddcddba1ee
ToppCell5'-Adult-SmallIntestine-Mesenchymal-fibroblastic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LAMC1 FBN1 TIMP1 ECM2 VCAN

1.75e-062004553a164e3971bcd62b148b813171c103adb81f972e
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

LAMC1 FBN1 ECM2 VCAN ZFPM2

1.75e-062004553dd022e974fec7013ba18f333da63f58fbf2dd7c
ToppCellParenchymal-NucSeq-Stromal-Fibroblastic-Fibro_adventitial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PAPPA FBN1 TIMP1 VCAN ZFPM2

1.75e-0620045574e74123ea7bf38d337a3a0248a6a51437c6ab42
ToppCellcellseq2-Mesenchymal-Fibroblastic|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

LAMC1 PAPPA FBN1 TIMP1 VCAN

1.75e-062004551c10597edd532bf172ca09870a937d35e2585081
ToppCellcellseq2-Mesenchymal-Fibroblastic-Fibroblastic_1|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

LAMC1 PAPPA FBN1 TIMP1 VCAN

1.75e-06200455440dda48b09c6a8581b7ca634b0d67f1ecacf65e
ToppCellTCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_Mucinous-3|TCGA-Stomach / Sample_Type by Project: Shred V9

PAPPA STAB2 DLL1 MUC2

1.51e-05148454c95a732163050cfb5d604c2a4c9eb1afa9f19a95
ToppCellTCGA-Bone_and_Soft_Tissue-Solid_Tissue_Normal|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

LRP2 UMOD CCL15 PLG

1.76e-0515445489a60a79d07466d7ad05888d10a72d3b1ab384af
ToppCellTCGA-Bone_and_Soft_Tissue-Solid_Tissue_Normal-Connective_tissue_normal|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

LRP2 UMOD CCL15 PLG

1.76e-05154454f1fea1a87e977221fa125b62287368be9af4987d
ToppCellTCGA-Bone_and_Soft_Tissue-Solid_Tissue_Normal-Connective_tissue_normal-Connective_tissue_normal|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

LRP2 UMOD CCL15 PLG

1.76e-05154454b5604c0b0b9b283352a3f612f40883b9123475d1
ToppCellTCGA-Bone_and_Soft_Tissue-Solid_Tissue_Normal-Connective_tissue_normal-Connective_tissue_normal-1|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

LRP2 UMOD CCL15 PLG

1.76e-05154454160b170a3ade8b246843c9854af332475c047ba0
ToppCell3'_v3-Lung-Lymphocytic_B-ABC_aged-B_memory|Lung / Manually curated celltypes from each tissue

BCL11A FCRL5 DLL1 CNTNAP2

2.26e-051644547766900740f67dbbe3c4d90fbfdcc1665cee6515
ToppCellPND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DNER FBN1 PLG TIMP1

2.54e-05169454031465190cd3623a25ef2b868daab8d932c8ff08
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FBN1 VCAN ZFPM2 CDC7

2.66e-05171454b0373ed8283ee1792b6a490bff93906546978593
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LRP2 PLG HECW1 INSR

2.66e-05171454f5014e3c387fe3118944af392abe10d6b9b0abab
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FBN1 VCAN ZFPM2 CDC7

2.66e-05171454b92963f9f247d2e5e2e6c51c6dbf70e527cd2f55
ToppCellPND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DNER FBN1 PLG TIMP1

2.66e-0517145415cb4670ff4234ac46aea8a5911138d6913c4482
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LRP2 PLG HECW1 INSR

3.04e-051774542f81b26be89cc2fd8eafadaf7eae3c6ad6521462
ToppCellPBMC-Convalescent-Lymphocyte-B-B_cell-B_naive-B_naive-9|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

LAMC1 BCL11A ZNF543 ZNF691

3.04e-05177454ae55773c531099a9e94f44f01ba48b5e71dddc53
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Rectal_Adenocarcinoma-7|TCGA-Colorectal / Sample_Type by Project: Shred V9

LAMC1 FBN1 VCAN KRT40

3.11e-05178454edc76b8f15056ec1c9a1c61a048b6331a92592d6
ToppCellCOVID-19-kidney-PCT-S1/S2|COVID-19 / Disease (COVID-19 only), tissue and cell type

LRP2 PAPPA PLG HECW1

3.11e-0517845423a12d3d971b857d5be8e907334d1f6b49eeeb32
ToppCellLA-01._Fibroblast_I|LA / Chamber and Cluster_Paper

LAMC1 FBN1 ZBTB20 VCAN

3.18e-05179454dcb6ec9ae72b13fe388b72dace2815293fafe8ee
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LRP2 PLG HECW1 INSR

3.25e-051804541363b3254470f6ff98630d1df83a1bdbacc137e0
ToppCellP28-Mesenchymal-mesenchymal_fibroblast-mesenchymal_alveolar_niche_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

DNER FBN1 TIMP1 VCAN

3.25e-051804549adebde5f4ca6dcb90e9113622862e14298465ac
ToppCellfacs-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FBN1 TIMP1 ECM2 VCAN

3.25e-0518045439ae8586efd91536e9ac6408d26de7e6d6237c41
ToppCellRA-01._Fibroblast_I|World / Chamber and Cluster_Paper

PAPPA FBN1 TIMP1 VCAN

3.32e-051814542b6ddeb53a79a658e2ba78527ff48c155b20daa6
ToppCellfacs-Pancreas-Exocrine-18m-Mesenchymal|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN1 TIMP1 ECM2 VCAN

3.32e-05181454269b39ac65790061d54eab47a8eeb024403f0348
ToppCellfacs-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN1 TIMP1 ECM2 VCAN

3.32e-05181454cd4f744b6b64ba6c22ec07afd1d3058a2546909d
ToppCellfacs-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN1 TIMP1 ECM2 VCAN

3.32e-05181454c8395ae872aa80b3ae1ab7c53e57b3ca15aeb0e2
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

LRP2 UMOD INSR CNTNAP2

3.32e-05181454c80ffa2ded5975a88e9a1a7d333196f95237bf0a
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LRP2 PLG HECW1 INSR

3.39e-051824544a9c13932e7163fd37a3dcc4c6ca3bbea5372459
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP2 STAB2 HECW1 OTOG

3.54e-051844542cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP2 STAB2 HECW1 OTOG

3.54e-05184454ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP2 STAB2 HECW1 OTOG

3.54e-051844542b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellCOVID-19-Heart-Fib_2|COVID-19 / Disease (COVID-19 only), tissue and cell type

LAMC1 FBN1 VCAN ZFPM2

3.61e-051854548f95d8e591bf7379d13f5a0545b0cb49e2b1ab5d
ToppCell343B-Fibroblasts-Fibroblast-E-|343B / Donor, Lineage, Cell class and subclass (all cells)

PAPPA FBN1 ECM2 ZFPM2

3.69e-051864541bac7825c2fe3e6cdff65026b09b9ccaa40fa27f
ToppCell343B-Fibroblasts-Fibroblast-E|343B / Donor, Lineage, Cell class and subclass (all cells)

PAPPA FBN1 ECM2 ZFPM2

3.69e-0518645459db239f1864a5d4f1570c93219dbd7ac5b6db35
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LRP2 PLG HECW1 INSR

3.69e-051864548287146f0ba415ea04475588117d4668ae00f75c
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LRP2 PLG HECW1 INSR

3.69e-05186454a417e1e21313a7e05951038cdef5ac672a9f727c
ToppCellLA-01._Fibroblast_I|World / Chamber and Cluster_Paper

LAMC1 FBN1 ZBTB20 VCAN

3.77e-051874544ea486991f66c29728d127171a07b81404ec0b78
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LRP2 PLG HECW1 INSR

3.77e-051874541b82920588f9e26ef1db244d452736d75fcfd342
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LRP2 PLG HECW1 INSR

3.77e-0518745471eb26ebf60cb0848e5bf1cd01edccda621aecd8
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LRP2 PLG HECW1 INSR

3.77e-05187454c1e4c0345f9bfa0538730bad5ff3fa5240168b25
DrugLY 294002; Up 200; 10uM; MCF7; HT_HG-U133A

PAPPA ADAM17 STAB2 VCAN ZFP64 CNTNAP2

1.59e-061884465596_UP
DrugD-Val-Phe-Lys-chloromethyl ketone

PLG TIMP1

3.65e-062442CID005491924
DrugNSC-343257

DNER PLG DLL1 TIMP1 VCAN INSR

4.85e-06228446CID000004242
DrugA0395

LAMB2 LAMC1 ADAM17 TIMP1

1.33e-0575444CID009906466
DrugAC1L1DD6

PAPPA ADAM17 PLG TIMP1 VCAN

2.41e-05179445CID000002299
DrugFurosemide [54-31-9]; Up 200; 12uM; PC3; HT_HG-U133A

PAPPA STAB2 ECM2 ZFPM2 CNTNAP2

3.45e-051934454503_UP
DrugUrapidil hydrochloride [64887-14-5]; Up 200; 9.4uM; PC3; HT_HG-U133A

ZBTB20 HECW1 NSD2 VCAN CRB1

3.54e-051944456696_UP
DrugTerconazole [67915-31-5]; Up 200; 7.6uM; MCF7; HT_HG-U133A

LRP2 LAMB2 BCL11A ZBTB20 CRB1

3.54e-051944452844_UP
DrugMolsidomine [25717-80-0]; Up 200; 16.6uM; MCF7; HT_HG-U133A

BCL11A FBN1 STAB2 MUC2 ZFP64

3.71e-051964452862_UP
DrugDelcorine; Up 200; 8.4uM; PC3; HT_HG-U133A

FBN1 STAB2 HECW1 MUC2 VCAN

3.71e-051964454275_UP
DrugTerconazole [67915-31-5]; Up 200; 7.6uM; MCF7; HT_HG-U133A

CACNA1H STAB2 MUC2 ZFP64 CNTNAP2

3.71e-051964454407_UP
DrugAlfuzosin hydrochloride [81403-68-1]; Up 200; 9.4uM; MCF7; HT_HG-U133A

STAB2 PLG MUC2 CRB1 INSR

3.81e-051974455605_UP
DrugBufexamac [2438-72-4]; Up 200; 18uM; MCF7; HT_HG-U133A

BCL11A HECW1 ECM2 VCAN CNTNAP2

3.90e-051984455515_UP
DrugCiprofloxacin hydrochloride [93107-08-5]; Up 200; 10.8uM; PC3; HT_HG-U133A

LRP2 HECW1 NSD2 VCAN ZFP64

3.99e-051994456700_UP
DrugCTMs

DNER TIMP1

5.45e-056442CID000192530
DrugFR 139317

LAMB2 TIMP1

7.62e-057442ctd:C079574
DrugRgd Peptide

LAMB2 LAMC1 FBN1 PLG TIMP1

9.51e-05239445CID000104802
Drugcobalt-60

DNER LAMB2 LAMC1 CACNA1H HECW1 TIMP1

9.90e-05390446CID000061492
DiseaseScoliosis, unspecified

DLL1 NOTCH1

4.99e-058402C0036439
Diseasediabetic nephropathy

UMOD LAMC1 PLG CNTNAP2

5.08e-05150404EFO_0000401
DiseaseFamilial thoracic aortic aneurysm and aortic dissection

FBN1 NOTCH1 VCAN

5.16e-0553403C4707243
DiseaseMarfan Syndrome, Type I

LAMC1 FBN1

6.41e-059402C4721845
DiseaseSemantic-Pragmatic Disorder

BCL11A CNTNAP2

9.78e-0511402C0454655
DiseaseAuditory Processing Disorder, Central

BCL11A CNTNAP2

9.78e-0511402C0751257
DiseaseLanguage Delay

BCL11A CNTNAP2

9.78e-0511402C0023012
DiseaseLanguage Development Disorders

BCL11A CNTNAP2

9.78e-0511402C0023014
DiseaseMarfan Syndrome

LAMC1 FBN1

9.78e-0511402C0024796
DiseaseSpeech Delay

BCL11A CNTNAP2

9.78e-0511402C0241210
Diseasemyocardial infarction

LAMB2 LAMC1 PLG ZFPM2 ZNF77

1.07e-04350405EFO_0000612
Diseasecaffeine measurement

LAMB2 LAMC1

1.86e-0415402EFO_0021177
Diseaseautism spectrum disorder (is_implicated_in)

BCL11A CNTNAP2

2.12e-0416402DOID:0060041 (is_implicated_in)
Diseasepre-malignant neoplasm (biomarker_via_orthology)

MUC2 INSR

2.41e-0417402DOID:0060071 (biomarker_via_orthology)
Diseasechronic kidney disease

LRP2 UMOD ECM2 ZNF77

2.86e-04235404EFO_0003884
DiseaseAdenoid Cystic Carcinoma

BCL11A NOTCH1 VCAN

3.41e-04100403C0010606
DiseaseCongenital diaphragmatic hernia

ZFPM2 INSR

3.70e-0421402C0235833
DiseasePR interval

LAMB2 LAMC1 EGFEM1P ZFPM2 CDC7

5.28e-04495405EFO_0004462
Diseasecreatinine measurement, glomerular filtration rate

LRP2 UMOD EGFEM1P

5.39e-04117403EFO_0004518, EFO_0005208
DiseaseMalignant neoplasm of breast

BCL11A FCRL5 DLL1 ZBTB3 NSD2 NOTCH1 ZFP64

5.41e-041074407C0006142
DiseaseHeart valve disease

TIMP1 NOTCH1

5.70e-0426402C0018824
DiseaseEndogenous Hyperinsulinism

FBN1 INSR

5.70e-0426402C1257963
DiseaseExogenous Hyperinsulinism

FBN1 INSR

5.70e-0426402C1257964
DiseaseCompensatory Hyperinsulinemia

FBN1 INSR

5.70e-0426402C1257965
DiseaseHyperinsulinism

FBN1 INSR

6.62e-0428402C0020459
DiseaseHyperglycemia, Postprandial

FBN1 INSR

7.61e-0430402C1855520
DiseaseHyperglycemia

FBN1 INSR

7.61e-0430402C0020456
Diseasehyperuricemia

LRP2 UMOD

9.21e-0433402EFO_0009104
Diseasefactor VIII measurement, venous thromboembolism

STAB2 ZFPM2

9.78e-0434402EFO_0004286, EFO_0004630
Diseaseliver cirrhosis (biomarker_via_orthology)

FBN1 MUC2

9.78e-0434402DOID:5082 (biomarker_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
GGTCYPTETSYVCTC

VCAN

3101

P13611
ADCCTSYISQSIPCS

CCL15

51

Q16663
SSNTCEPCSAYVICT

KRT40

411

Q6A162
TDCVDSYTCTCPAGF

NOTCH1

961

P46531
SCCSPSCYSSSCYST

HECW1

676

Q76N89
PGASLKCTVCSYTAD

ZFPM2

331

Q8WW38
GICKDEPSSYTCTTC

BCL11A

161

Q9H165
CTGYKESCCPVSSNT

FCRL5

166

Q96RD9
GSPVYSSKCQDCVCT

MUC2

4936

Q02817
TAFSCTPDGRSYCCE

NSD2

1311

O96028
STPCDPNSGSCYCKR

LAMB2

481

P55268
CTDTLTSFYCSCRPG

LRP2

3126

P98164
EYEDSAGECCSCPKT

INSR

701

P06213
CNYDGGDCCTSTVKT

PAPPA

1576

Q13219
TASSCPASLTCDCYA

CDC7

341

O00311
PASLTCDCYATDKVC

CDC7

346

O00311
GSCTDLENSYSCTCP

DLL1

341

O00548
NCEKKIDYCSSSPCS

DLL1

401

O00548
GAVTKSECCCASTEY

FBN1

676

P35555
GECCPVCSATVSYSL

ECM2

151

O94769
KPVYCVPVCSGDSSC

KRTAP10-7

121

P60409
CSKSVCYVPVCSGAS

KRTAP10-10

151

P60014
LSTQCDSYGRCSCKP

LAMC1

406

P11047
FKCTCDETGYSGATC

CNTNAP2

576

Q9UHC6
CKCPPGYSGTICETT

CRB1

96

P82279
GTLTCELKSCPYCTR

CACNA1H

691

O95180
TCRSVGTSYKCLCDP

DNER

481

Q8NFT8
NCDCTPDYTRKSCTI

EGFEM1P

126

Q0D2K5
CALSCEASKEYSPCV

OTOG

776

Q6ZRI0
TDSEPYSCSKSCSRT

RAPGEF6

1406

Q8TEU7
EPYCSCSDCQSPLST

TMCO2

161

Q7Z6W1
CYSTPSGCLELTDSC

NBPF10

1371

Q6P3W6
CYSTPSSCLEQPDSC

NBPF10

1521

Q6P3W6
CYSTPSGCLELTDSC

NBPF10

2591

Q6P3W6
CYSTPSSCLEQPDSC

NBPF10

2741

Q6P3W6
CYSTPSGCLELTDSC

NBPF19

856

A0A087WUL8
CYSTPSSCLEQPDSC

NBPF19

1006

A0A087WUL8
CYSTPSGCLELTDSC

NBPF19

2076

A0A087WUL8
CYSTPSSCLEQPDSC

NBPF19

2226

A0A087WUL8
CYSTPSGCLELTDSC

NBPF19

3296

A0A087WUL8
CYSTPSSCLEQPDSC

NBPF19

3446

A0A087WUL8
CYSTPSGCLELTDSC

NBPF20

756

P0DPF2
CYSTPSSCLEQPDSC

NBPF20

906

P0DPF2
CYSTPSGCLELTDSC

NBPF20

1976

P0DPF2
CYSTPSSCLEQPDSC

NBPF20

2126

P0DPF2
CYSTPSSCLEQPDSC

NBPF20

3346

P0DPF2
CYSTPSSCLEQPDSC

NBPF20

4491

P0DPF2
PCNEKCRCSSSIYSS

SLCO6A1

501

Q86UG4
YCKIPSCDSSPVSTE

PLG

346

P00747
TCKGVSYCTGNSSEC

ADAM17

541

P78536
KTYTVGCEECTVFPC

TIMP1

141

P01033
PYECTECGKAYSCSS

ZNF77

491

Q15935
PYICCECGKSFSNSS

ZNF691

226

Q5VV52
YCTDPSSVEGTCEEC

UMOD

286

P07911
ATCEYSNGTASCICK

STAB2

841

Q8WWQ8
VVACTEGTTYVCSVC

ZBTB20

706

Q9HC78
PYECTECGKTFSKST

ZNF543

226

Q08ER8
KCPECSYSCSSAAAL

ZFP64

496

Q9NTW7
CIDCTTNFSCTYGKP

TM2D3

81

Q9BRN9
VPTCKTCGKTFSCSY

ZBTB3

471

Q9H5J0