Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	APOBEC_N	APOBEC3D APOBEC4	4.93e-04	12	52	2	PF08210
Domain	APOBEC_N	APOBEC3D APOBEC4	4.93e-04	12	52	2	IPR013158
Domain	CYT_DCMP_DEAMINASES_1	APOBEC3D APOBEC4	1.01e-03	17	52	2	PS00903
Domain	CMP_dCMP_Zn-bd	APOBEC3D APOBEC4	1.01e-03	17	52	2	IPR002125
Domain	-	NPHP3 OGT SPATA16 P3H4	2.62e-03	207	52	4	1.25.40.10
Domain	TPR-like_helical_dom	NPHP3 OGT SPATA16 P3H4	4.00e-03	233	52	4	IPR011990
Pubmed	NEUROD polymorphism Ala45Thr is associated with Type 1 diabetes mellitus in Czech children.	NEUROD1 HLA-DQB1	1.36e-05	4	53	2	12639765
Pubmed	INSM1 functions as a transcriptional repressor of the neuroD/beta2 gene through the recruitment of cyclin D1 and histone deacetylases.	HDAC3 NEUROD1	2.27e-05	5	53	2	16569215
Pubmed	Schwannoma development is mediated by Hippo pathway dysregulation and modified by RAS/MAPK signaling.	FOXN1 LATS2	4.76e-05	7	53	2	32960816
Pubmed	HDAC3 Is a Master Regulator of mTEC Development.	FOXN1 HDAC3	6.34e-05	8	53	2	27068467
Pubmed	The chromosomal distribution of mouse odorant receptor genes.	OR8B2 OR8B3 OR8B8	7.84e-05	54	53	3	8570653
Pubmed	Ptf1a determines horizontal and amacrine cell fates during mouse retinal development.	NEUROD1 FOXN4	8.15e-05	9	53	2	17075007
Pubmed	Interaction of nuclear receptor zinc finger DNA binding domains with histone deacetylase.	HDAC3 IKZF2	1.24e-04	11	53	2	12943985
Pubmed	Characterization of Olig2 expression during cerebellar development.	NEUROD1 SKOR2	1.76e-04	13	53	2	24594479
Pubmed	Ikaros confers early temporal competence to mouse retinal progenitor cells.	IKZF2 NEUROD1	1.76e-04	13	53	2	18940586
Pubmed	A molecular dissection of the repression circuitry of Ikaros.	HDAC3 IKZF2	2.05e-04	14	53	2	12015313
Pubmed	Enoyl-CoA hydratase-1 regulates mTOR signaling and apoptosis by sensing nutrients.	WDR87 BRWD3	2.05e-04	14	53	2	28878358
Pubmed	Rp58 is essential for the growth and patterning of the cerebellum and for glutamatergic and GABAergic neuron development.	NEUROD1 SKOR2	2.36e-04	15	53	2	22513377
Pubmed	Ptf1a is essential for the differentiation of GABAergic and glycinergic amacrine cells and horizontal cells in the mouse retina.	NEUROD1 FOXN4	2.70e-04	16	53	2	17301087
Pubmed	Regenerative Reprogramming of the Intestinal Stem Cell State via Hippo Signaling Suppresses Metastatic Colorectal Cancer.	FOXN1 LATS2	2.70e-04	16	53	2	32730753
Pubmed	The Lim homeobox gene Lhx2 is required for olfactory sensory neuron identity.	NEUROD1 OR8B8	3.05e-04	17	53	2	15456728
Pubmed	The bone microenvironment invigorates metastatic seeds for further dissemination.	FOXN1 APOBEC3D	3.05e-04	17	53	2	33878291
Pubmed	A Non-catalytic Function of SETD1A Regulates Cyclin K and the DNA Damage Response.	OGT CCNK	3.43e-04	18	53	2	29474905
Pubmed	Foxn4 controls the genesis of amacrine and horizontal cells by retinal progenitors.	NEUROD1 FOXN4	3.83e-04	19	53	2	15363391
Pubmed	Altered visual function and interneuron survival in Atrx knockout mice: inference for the human syndrome.	NEUROD1 FOXN4	4.25e-04	20	53	2	19088125
Pubmed	Zac1 functions through TGFbetaII to negatively regulate cell number in the developing retina.	NEUROD1 FOXN4	4.70e-04	21	53	2	17559664
Pubmed	Sip1 regulates the generation of the inner nuclear layer retinal cell lineages in mammals.	NEUROD1 FOXN4	4.70e-04	21	53	2	27385012
Pubmed	Elavl2 Regulates Retinal Function Via Modulating the Differentiation of Amacrine Cells Subtype.	NEUROD1 FOXN4	6.16e-04	24	53	2	34061953
Pubmed	An interaction between OTULIN and SCRIB uncovers roles for linear ubiquitination in planar cell polarity.	CALU SNX27	6.68e-04	25	53	2	37589075
Pubmed	GDF11 controls the timing of progenitor cell competence in developing retina.	NEUROD1 FOXN4	6.68e-04	25	53	2	15976303
Pubmed	Crucial role for Mst1 and Mst2 kinases in early embryonic development of the mouse.	NEUROD1 LATS2	6.68e-04	25	53	2	19786569
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	DOCK3 ATP6V0A1 OGT WASHC4 FBXO11 PC BRWD3 SOS2	6.87e-04	1285	53	8	35914814
Pubmed	Forkhead box N4 (Foxn4) activates Dll4-Notch signaling to suppress photoreceptor cell fates of early retinal progenitors.	NEUROD1 FOXN4	7.80e-04	27	53	2	22323600
Pubmed	An isoform of retinoid-related orphan receptor β directs differentiation of retinal amacrine and horizontal interneurons.	NEUROD1 FOXN4	9.01e-04	29	53	2	23652001
Pubmed	Proteomic analysis of early melanosomes: identification of novel melanosomal proteins.	ATP6V0A1 CALU	9.01e-04	29	53	2	12643545
Pubmed	Pax6 is required for normal cell-cycle exit and the differentiation kinetics of retinal progenitor cells.	NEUROD1 FOXN4	9.64e-04	30	53	2	24073291
Pubmed	Role of Elavl-like RNA-binding protein in retinal development and signal transduction.	NEUROD1 FOXN4	1.03e-03	31	53	2	39307290
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	NPHP3 NEUROD1 OGT SLFN12 SNX27 FBXO11 PRAMEF12	1.24e-03	1084	53	7	11544199
Pubmed	Histone Deacetylase 3 Governs Perinatal Cerebral Development via Neural Stem and Progenitor Cells.	HDAC3 NEUROD1	1.24e-03	34	53	2	31569049
Pubmed	Roles for Dicer1 in the patterning and differentiation of the optic cup neuroepithelium.	NEUROD1 FOXN4	1.24e-03	34	53	2	21138975
Pubmed	Prdm12 represses the expression of the visceral neuron determinants Phox2a/b in developing somatosensory ganglia.	NEUROD1 SKOR2	1.31e-03	35	53	2	38025786
Cytoband	Xq21.1	P2RY10 BRWD3	6.75e-04	33	53	2	Xq21.1
Cytoband	12q24.11	WASHC4 FOXN4	6.75e-04	33	53	2	12q24.11
Cytoband	Ensembl 112 genes in cytogenetic band chr11q24	OR8B2 OR8B3 OR8B8	1.42e-03	191	53	3	chr11q24
Cytoband	11q24.2	OR8B3 OR8B8	2.44e-03	63	53	2	11q24.2
GeneFamily	Olfactory receptors, family 8	OR8B2 OR8B3 OR8B8	1.60e-04	49	39	3	155
GeneFamily	Apolipoprotein B mRNA editing enzyme catalytic subunits	APOBEC3D APOBEC4	2.95e-04	12	39	2	406
GeneFamily	Forkhead boxes	FOXN1 FOXN4	3.87e-03	43	39	2	508
Disease	Generalized hypotonia	PIGB SNX27	2.80e-04	15	49	2	C1858120
Disease	bilirubin measurement	HLA-DQB1 SPATA16 SLCO1B3 TRIB1 SOS2	8.18e-04	442	49	5	EFO_0004570
Disease	Crohn's disease (is_implicated_in)	BPI HLA-DQB1	1.14e-03	30	49	2	DOID:8778 (is_implicated_in)
Disease	low density lipoprotein cholesterol measurement, C-reactive protein measurement	HLA-DQB1 TRIB1	1.55e-03	35	49	2	EFO_0004458, EFO_0004611

Protein segments in the cluster

Peptide	Gene	Start	Entry
EAMYPHIFYFHFKNL	APOBEC3D	206	Q96AK3
SIYFSQLYHTEMDFP	APOBEC4	151	Q8WW27
FYMFHSFKQFPRYVT	CCNK	81	O75909
KYYEKIPDQMFFHTD	BRWD3	546	Q6RI45
FTAFLHPEEYDYMKD	CALU	176	O43852
HTPMYFFLYNLSFID	OR8B8	56	Q15620
VDVKLYTPMYFFLSH	OR9I1	51	Q8NGQ6
SYSPYAFKFFMEQHV	LATS2	596	Q9NRM7
FFSGYTFKHKMVYED	F8	671	P00451
HTPMYYFLFNLSFID	OR8B3	56	Q8NGG8
RFSYPDIHFDMNLTY	IKZF2	291	Q9UKS7
MYFELPDSFQHYRSV	NBPF1	1161	Q3BBV0
RVMTVSFHKYGNYFF	HDAC3	186	O15379
IMDVFKTGYYSSFFE	OTOP2	116	Q7RTS6
DYFQKLYMHSVSFLE	PRAMEF12	266	O95522
PEDFVYQFKAMCYFT	HLA-DQB1	36	P01920
DNTYNVVHMKDFFYF	DYRK4	161	Q9NR20
DHFNMFTGKFYCYVP	C1QTNF1	176	Q9BXJ1
DIKYFHFRPVMDTYI	DOCK3	676	Q8IZD9
LYKISSYTSYPMHDF	FBXO11	836	Q86XK2
HYSFYSMDIREFQLP	BPI	81	P17213
FTPYHINFIFYTMVK	P2RY10	256	O00398
QYSEKLAYMPHTFFI	OGT	691	O15294
HTPMYYFLFNLSFID	OR8B2	56	Q96RD0
YFSFDEFMVPYFGRH	PGBD3	266	Q8N328
VSEIYSFMKEHFPYF	FOXN4	216	Q96NZ1
VYSMLSHKEFRFIYP	PIGB	351	Q92521
MSHTLIYIPSYFDFV	UTP25	611	Q68CQ4
LTYHMYADPNFVRTF	SOS2	611	Q07890
TMGYFFHAVYFPIDV	NPHP3	331	Q7Z494
AIHKYAFMTSDYPVV	PLCZ1	231	Q86YW0
EIYNFMTEHFPYFKT	FOXN1	296	O15353
YTPQFKVFTVSYFHE	NFAM1	71	Q8NET5
AFTKTHPAYAEYMYT	SPATA16	346	Q9BXB7
CVFHSKYAGFMVPYF	TAS2R1	141	Q9NYW7
AYVFFEKDFGDMHSY	TRIB1	156	Q96RU8
PEYMLEKSFYQFQHY	MTREX	581	P42285
VSFYYFFLMVAGHPN	SULT1E1	136	P49888
EFYFRYPSFQDVHAM	RHBG	56	Q9H310
YFVDKFVATMYHYLQ	P3H4	286	Q92791
SFIGSFTYVFKYMEQ	SLCO1B3	351	Q9NPD5
GHFYDYPMALFSTFE	TRPV6	561	Q9H1D0
YTFHMVQDEEFKGYS	SLFN12	456	Q8IYM2
KIFTPYFNYMHECFE	SNX27	501	Q96L92
GQFLHYIFPYQFMDS	POPDC2	171	Q9HBU9
YCNMYFSPNKFIFHS	SKOR2	176	Q2VWA4
HFINMFLFSYPESGY	ATP6V0A1	611	Q93050
RSGYIFFYMHKEIFD	USP37	941	Q86T82
FFPHFKYSMDTYVFK	UEVLD	31	Q8IX04
YIFSQFMYDEHIKSR	WASHC4	851	Q2M389
SFFFSFETMFVPKYI	WDR87	666	Q6ZQQ6
AMYPDVFAHFKDFTA	PC	1011	P11498
AEFEKNYAFTMHYPA	NEUROD1	291	Q13562