Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionolfactory receptor activity

OR2T29 OR10A2 OR2T35 OR9G4 OR2T5 OR2T6 OR13C9 OR2AT4 OR56A5 OR5L2 OR8D4 GPR148

1.33e-064319812GO:0004984
GeneOntologyMolecularFunctionG protein-coupled receptor activity

OR2T29 NPY1R OR10A2 OR2T35 GPR39 OR9G4 OR2T5 GALR2 OR2T6 OR13C9 OR2AT4 OR56A5 OR5L2 OR8D4 GPR148

2.57e-058849815GO:0004930
GeneOntologyMolecularFunctionATP-dependent activity

ABCC3 MYO9A KIF12 MORC4 ABCC6 RECQL5 DNAH17 MTREX TAP1 DNAH9 ABCG5 DNAH11

4.68e-056149812GO:0140657
GeneOntologyMolecularFunctionATP hydrolysis activity

ABCC3 KIF12 MORC4 ABCC6 RECQL5 MTREX TAP1 DNAH9 ABCG5 DNAH11

6.17e-054419810GO:0016887
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DNAH17 DNAH9 DNAH11

8.87e-0518983GO:0008569
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

OR2T29 NPY1R OR10A2 OR2T35 GPR39 OR9G4 TMEM63C OR2T5 GALR2 ZACN OR2T6 OR13C9 OR2AT4 OR56A5 TNF OR5L2 OR8D4 GPR148

9.24e-0513539818GO:0004888
GeneOntologyMolecularFunctionABC-type transporter activity

ABCC3 ABCC6 TAP1 ABCG5

9.76e-0549984GO:0140359
GeneOntologyMolecularFunctionryanodine-sensitive calcium-release channel activity

RYR2 RYR3

1.42e-044982GO:0005219
GeneOntologyMolecularFunctiontransmembrane transporter activity

ABCC3 TMEM63C MFSD9 TMEM87A ABCC6 PANX3 RYR2 RYR3 KCNH4 GJB1 ZACN SLC22A8 TAP1 SLC38A6 SLC38A3 ABCG5

1.93e-0411809816GO:0022857
GeneOntologyMolecularFunctioncytoskeletal motor activity

MYO9A KIF12 DNAH17 DNAH9 DNAH11

2.90e-04118985GO:0003774
GeneOntologyMolecularFunctiondynein light intermediate chain binding

DNAH17 DNAH9 DNAH11

3.44e-0428983GO:0051959
GeneOntologyMolecularFunctioncalcium-induced calcium release activity

RYR2 RYR3

3.53e-046982GO:0048763
GeneOntologyMolecularFunctionmicrotubule motor activity

KIF12 DNAH17 DNAH9 DNAH11

3.90e-0470984GO:0003777
GeneOntologyMolecularFunctiontransporter activity

ABCC3 TMEM63C MFSD9 TMEM87A ABCC6 PANX3 RYR2 RYR3 KCNH4 GJB1 ZACN SLC22A8 TAP1 SLC38A6 SLC38A3 ABCG5

5.16e-0412899816GO:0005215
GeneOntologyMolecularFunctionxenobiotic transmembrane transporter activity

ABCC3 ABCC6 SLC22A8

6.14e-0434983GO:0042910
GeneOntologyMolecularFunctionABC-type glutathione S-conjugate transporter activity

ABCC3 ABCC6

6.55e-048982GO:0015431
GeneOntologyMolecularFunctionbHLH transcription factor binding

TCF15 TCF21 SCX

7.89e-0437983GO:0043425
GeneOntologyMolecularFunctiondynein intermediate chain binding

DNAH17 DNAH9 DNAH11

7.89e-0437983GO:0045505
GeneOntologyMolecularFunctionL-glutamine transmembrane transporter activity

SLC38A6 SLC38A3

8.39e-049982GO:0015186
GeneOntologyMolecularFunctionATPase-coupled inorganic anion transmembrane transporter activity

ABCC3 ABCC6

1.05e-0310982GO:0043225
GeneOntologyMolecularFunctionsulfur compound binding

HPSE2 ADAMTS5 RYR2 GSTP1 FBN1 FURIN SOAT2

1.07e-03323987GO:1901681
GeneOntologyMolecularFunctionmonoatomic cation channel activity

TMEM63C TMEM87A PANX3 RYR2 RYR3 KCNH4 ZACN

1.51e-03343987GO:0005261
GeneOntologyMolecularFunctionATPase-coupled transmembrane transporter activity

ABCC3 ABCC6 TAP1 ABCG5

2.05e-03109984GO:0042626
GeneOntologyMolecularFunctionABC-type xenobiotic transporter activity

ABCC3 ABCC6

2.40e-0315982GO:0008559
GeneOntologyMolecularFunctionicosanoid transmembrane transporter activity

ABCC3 SLC22A8

2.40e-0315982GO:0071714
GeneOntologyBiologicalProcesssensory perception

OR2T29 DMXL2 NPY1R OR10A2 MYO9A OR2T35 OR9G4 OR2T5 TMEM87A ABCC6 OR2T6 OR13C9 OR2AT4 OR56A5 FSCN2 TNF PPIP5K2 OR5L2 OR8D4 GPR148

2.09e-07107210120GO:0007600
GeneOntologyBiologicalProcessdetection of stimulus

OR2T29 OR10A2 OR2T35 OR9G4 OR2T5 TMEM87A RYR2 JUP OR2T6 OR13C9 OR2AT4 OR56A5 TNF OR5L2 OR8D4 GPR148

4.31e-0772210116GO:0051606
GeneOntologyBiologicalProcesssensory perception of smell

OR2T29 DMXL2 OR10A2 OR2T35 OR9G4 OR2T5 OR2T6 OR13C9 OR2AT4 OR56A5 OR5L2 OR8D4 GPR148

4.42e-0746510113GO:0007608
GeneOntologyBiologicalProcessdetection of stimulus involved in sensory perception

OR2T29 OR10A2 OR2T35 OR9G4 OR2T5 TMEM87A OR2T6 OR13C9 OR2AT4 OR56A5 TNF OR5L2 OR8D4 GPR148

9.33e-0758210114GO:0050906
GeneOntologyBiologicalProcessdetection of chemical stimulus involved in sensory perception of smell

OR2T29 OR10A2 OR2T35 OR9G4 OR2T5 OR2T6 OR13C9 OR2AT4 OR56A5 OR5L2 OR8D4 GPR148

1.36e-0643210112GO:0050911
GeneOntologyBiologicalProcessdetection of chemical stimulus

OR2T29 OR10A2 OR2T35 OR9G4 OR2T5 RYR2 OR2T6 OR13C9 OR2AT4 OR56A5 OR5L2 OR8D4 GPR148

1.68e-0652410113GO:0009593
GeneOntologyBiologicalProcesssensory perception of chemical stimulus

OR2T29 DMXL2 OR10A2 OR2T35 OR9G4 OR2T5 OR2T6 OR13C9 OR2AT4 OR56A5 OR5L2 OR8D4 GPR148

2.70e-0654710113GO:0007606
GeneOntologyBiologicalProcessdetection of chemical stimulus involved in sensory perception

OR2T29 OR10A2 OR2T35 OR9G4 OR2T5 OR2T6 OR13C9 OR2AT4 OR56A5 OR5L2 OR8D4 GPR148

4.47e-0648510112GO:0050907
DomainGPCR_Rhodpsn_7TM

OR2T29 NPY1R OR10A2 OR2T35 GPR39 OR9G4 OR2T5 GALR2 OR2T6 OR13C9 OR2AT4 OR56A5 OR5L2 OR8D4 GPR148

3.05e-0667010115IPR017452
Domain7tm_1

OR2T29 NPY1R OR10A2 OR2T35 GPR39 OR9G4 OR2T5 GALR2 OR2T6 OR13C9 OR2AT4 OR56A5 OR5L2 OR8D4 GPR148

3.46e-0667710115PF00001
DomainG_PROTEIN_RECEP_F1_1

OR2T29 NPY1R OR10A2 OR2T35 GPR39 OR9G4 OR2T5 GALR2 OR2T6 OR13C9 OR2AT4 OR56A5 OR5L2 OR8D4 GPR148

4.00e-0668510115PS00237
DomainG_PROTEIN_RECEP_F1_2

OR2T29 NPY1R OR10A2 OR2T35 GPR39 OR9G4 OR2T5 GALR2 OR2T6 OR13C9 OR2AT4 OR56A5 OR5L2 OR8D4 GPR148

4.44e-0669110115PS50262
DomainGPCR_Rhodpsn

OR2T29 NPY1R OR10A2 OR2T35 GPR39 OR9G4 OR2T5 GALR2 OR2T6 OR13C9 OR2AT4 OR56A5 OR5L2 OR8D4 GPR148

4.52e-0669210115IPR000276
DomainOlfact_rcpt

OR2T29 OR10A2 OR2T35 OR9G4 OR2T5 OR2T6 OR13C9 OR2AT4 OR56A5 OR5L2 OR8D4

9.08e-0639310111IPR000725
DomainARM-type_fold

GBF1 TSC2 FRYL RYR3 FOCAD RANBP17 JUP URB1 DAAM2 GCN1

1.51e-0533910110IPR016024
DomainTILa

ZAN FCGBP

8.66e-0531012PF12714
DomainTILa_dom

ZAN FCGBP

8.66e-0531012IPR025615
DomainRyanrecept_TM4-6

RYR2 RYR3

8.66e-0531012IPR009460
DomainRyR

RYR2 RYR3

8.66e-0531012PF02026
DomainRyanodine_rcpt

RYR2 RYR3

8.66e-0531012IPR003032
DomainRR_TM4-6

RYR2 RYR3

8.66e-0531012PF06459
DomainRyan_recept

RYR2 RYR3

8.66e-0531012IPR013333
DomainABC_tran

ABCC3 ABCC6 TAP1 ABCG5

1.31e-04481014PF00005
DomainABC_TRANSPORTER_2

ABCC3 ABCC6 TAP1 ABCG5

1.31e-04481014PS50893
DomainAAA+_ATPase

ABCC3 ABCC6 TAP1 DNAH9 ABCG5 DNAH11

1.31e-041441016IPR003593
DomainAAA

ABCC3 ABCC6 TAP1 DNAH9 ABCG5 DNAH11

1.31e-041441016SM00382
DomainABC_TRANSPORTER_1

ABCC3 ABCC6 TAP1 ABCG5

1.42e-04491014PS00211
DomainABC_transporter-like

ABCC3 ABCC6 TAP1 ABCG5

1.53e-04501014IPR003439
DomainMultidrug-R_assoc

ABCC3 ABCC6

1.73e-0441012IPR005292
DomainABC_membrane

ABCC3 ABCC6 TAP1

2.86e-04241013PF00664
DomainRIH_assoc

RYR2 RYR3

4.28e-0461012PF08454
DomainRIH_assoc-dom

RYR2 RYR3

4.28e-0461012IPR013662
DomainRIH_dom

RYR2 RYR3

4.28e-0461012IPR000699
DomainIns145_P3_rcpt

RYR2 RYR3

4.28e-0461012IPR014821
DomainRyanodine_recept-rel

RYR2 RYR3

4.28e-0461012IPR015925
Domain-

RYR2 RYR3

4.28e-04610121.25.10.30
DomainRYDR_ITPR

RYR2 RYR3

4.28e-0461012PF01365
DomainIns145_P3_rec

RYR2 RYR3

4.28e-0461012PF08709
DomainABC_TM1F

ABCC3 ABCC6 TAP1

4.56e-04281013PS50929
DomainABC1_TM_dom

ABCC3 ABCC6 TAP1

4.56e-04281013IPR011527
DomainDHC_N1

DNAH9 DNAH11

7.94e-0481012PF08385
DomainDynein_heavy_dom-1

DNAH9 DNAH11

7.94e-0481012IPR013594
DomainMIR

RYR2 RYR3

1.27e-03101012PS50919
DomainMIR

RYR2 RYR3

1.27e-03101012PF02815
DomainMIR

RYR2 RYR3

1.27e-03101012SM00472
DomainMIR_motif

RYR2 RYR3

1.27e-03101012IPR016093
Domain-

TSC2 FRYL RANBP17 JUP DAAM2 GCN1

1.31e-0322210161.25.10.10
DomainABC_transporter_CS

ABCC3 ABCC6 TAP1

1.51e-03421013IPR017871
DomainTIL

ZAN FCGBP

1.84e-03121012PF01826
DomainC8

ZAN FCGBP

1.84e-03121012PF08742
DomainUnchr_dom_Cys-rich

ZAN FCGBP

2.17e-03131012IPR014853
DomainC8

ZAN FCGBP

2.17e-03131012SM00832
DomainDynein_heavy_chain_D4_dom

DNAH9 DNAH11

2.53e-03141012IPR024317
DomainDynein_HC_stalk

DNAH9 DNAH11

2.53e-03141012IPR024743
DomainDynein_heavy_dom-2

DNAH9 DNAH11

2.53e-03141012IPR013602
DomainDHC_N2

DNAH9 DNAH11

2.53e-03141012PF08393
DomainMT

DNAH9 DNAH11

2.53e-03141012PF12777
DomainAAA_8

DNAH9 DNAH11

2.53e-03141012PF12780
DomainTIL_dom

ZAN FCGBP

2.53e-03141012IPR002919
DomainATPase_dyneun-rel_AAA

DNAH9 DNAH11

2.53e-03141012IPR011704
DomainAAA_5

DNAH9 DNAH11

2.53e-03141012PF07728
Domain-

TCF15 TCF21 SCX TCF24

2.90e-0310910144.10.280.10
DomainDHC_fam

DNAH9 DNAH11

2.90e-03151012IPR026983
DomainDynein_heavy_dom

DNAH9 DNAH11

2.90e-03151012IPR004273
DomainDynein_heavy

DNAH9 DNAH11

2.90e-03151012PF03028
DomainHLH

TCF15 TCF21 SCX TCF24

3.10e-031111014PF00010
DomainVWD

ZAN FCGBP

3.31e-03161012SM00216
DomainVWF_type-D

ZAN FCGBP

3.31e-03161012IPR001846
DomainVWFD

ZAN FCGBP

3.31e-03161012PS51233
DomainVWD

ZAN FCGBP

3.31e-03161012PF00094
DomainARM-like

TSC2 FRYL RANBP17 JUP DAAM2 GCN1

3.48e-032701016IPR011989
DomainHLH

TCF15 TCF21 SCX TCF24

3.63e-031161014SM00353
DomainAa_trans

SLC38A6 SLC38A3

3.73e-03171012PF01490
DomainAA_transpt_TM

SLC38A6 SLC38A3

3.73e-03171012IPR013057
DomainBHLH

TCF15 TCF21 SCX TCF24

3.74e-031171014PS50888
DomainbHLH_dom

TCF15 TCF21 SCX TCF24

3.86e-031181014IPR011598
DomainVWC_out

ZAN FCGBP

4.66e-03191012SM00215
PathwayREACTOME_OLFACTORY_SIGNALING_PATHWAY

OR2T29 OR10A2 OR2T35 OR9G4 OR2T5 OR2T6 OR13C9 OR2AT4 OR56A5 OR5L2 OR8D4

1.19e-054177511M4072
PathwayKEGG_OLFACTORY_TRANSDUCTION

OR2T29 OR10A2 OR9G4 OR2T5 OR2T6 OR13C9 OR2AT4 OR56A5 OR5L2 OR8D4

3.82e-053897510M14091
PathwayKEGG_ABC_TRANSPORTERS

ABCC3 ABCC6 TAP1 ABCG5

8.54e-0544754M11911
PathwayREACTOME_SENSORY_PERCEPTION

OR2T29 OR10A2 OR2T35 OR9G4 OR2T5 OR2T6 OR13C9 OR2AT4 OR56A5 FSCN2 OR5L2 OR8D4

1.23e-046367512M41834
PathwayWP_PHOTODYNAMIC_THERAPYINDUCED_NFE2L2_NRF2_SURVIVAL_SIGNALING

ABCC3 ABCC6 GSTP1

2.37e-0423753M39709
PathwayWP_POSTCOVID_NEUROINFLAMMATION

TLR8 FURIN TNF

2.37e-0423753M48313
PathwayBIOCARTA_MRP_PATHWAY

ABCC3 GSTP1

2.76e-045752MM1586
Pubmed

Different evolutionary processes shaped the mouse and human olfactory receptor gene families.

OR2T29 OR10A2 OR2T35 OR9G4 OR2T5 OR2T6 OR2AT4 OR56A5 OR5L2 OR8D4

7.37e-083401031011875048
Pubmed

The olfactory receptor gene superfamily of the mouse.

OR2T29 OR10A2 OR2T35 OR9G4 OR2T5 OR2T6 OR2AT4 OR56A5 OR5L2 OR8D4

7.37e-083401031011802173
Pubmed

A unified nomenclature for vertebrate olfactory receptors.

OR2T29 OR10A2 OR2T35 OR9G4 OR2T5 OR2T6 OR2AT4 OR56A5 OR5L2 OR8D4

8.00e-083431031032295537
Pubmed

Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels.

OR2T29 OR10A2 OR2T35 OR9G4 OR2T5 OR2T6 OR2AT4 OR56A5 OR5L2 OR8D4

8.68e-083461031014611657
Pubmed

Fulfilling the promise of personalized medicine? Systematic review and field synopsis of pharmacogenetic studies.

GSTP1 FCGBP SLC22A8 KMT2A TNF ABCG5

8.73e-07108103619956635
Pubmed

Mutations in DNAH17, Encoding a Sperm-Specific Axonemal Outer Dynein Arm Heavy Chain, Cause Isolated Male Infertility Due to Asthenozoospermia.

DNAH17 DNAH9 DNAH11

8.75e-077103331178125
Pubmed

Furin-processed antigens targeted to the secretory route elicit functional TAP1-/-CD8+ T lymphocytes in vivo.

FURIN TAP1

8.69e-062103219752221
Pubmed

Decreased Toll-like receptor 8 expression and lower TNF-α synthesis in infants with acute RSV infection.

TLR8 TNF

8.69e-062103220946625
Pubmed

Translocation (4;11)(p12;q23) with rearrangement of FRYL and MLL in therapy-related acute myeloid leukemia.

FRYL KMT2A

8.69e-062103217854671
Pubmed

Inhibitors of TLR8 reduce TNF production from human rheumatoid synovial membrane cultures.

TLR8 TNF

8.69e-062103219017992
Pubmed

Tissue-specific alternative splicing of mouse brain type ryanodine receptor/calcium release channel mRNA.

RYR2 RYR3

8.69e-06210328898078
Pubmed

The mouse sino-atrial node expresses both the type 2 and type 3 Ca(2+) release channels/ryanodine receptors.

RYR2 RYR3

8.69e-062103214550562
Pubmed

AF4p12, a human homologue to the furry gene of Drosophila, as a novel MLL fusion partner.

FRYL KMT2A

8.69e-062103216061630
Pubmed

Direct inhibition of TNF-α promoter activity by Fanconi anemia protein FANCD2.

FANCD2 TNF

8.69e-062103221912593
Pubmed

Altered ryanodine receptor expression in mild cognitive impairment and Alzheimer's disease.

RYR2 RYR3

8.69e-062103221531043
Pubmed

Modulation of calcium signalling by dominant negative splice variant of ryanodine receptor subtype 3 in native smooth muscle cells.

RYR2 RYR3

8.69e-062103216678258
Pubmed

Activation of human bronchial epithelial cells by inflammatory cytokines IL-27 and TNF-alpha: implications for immunopathophysiology of airway inflammation.

TNF IL27

8.69e-062103220301193
Pubmed

Investigation of TNF-alpha gene (G308A) and GSTP1 gene (Ilel05Val) polymorphisms in Turkish patients with retinopathy of prematurity.

GSTP1 TNF

8.69e-062103225790547
Pubmed

Increased serum levels of TNF-α and decreased serum levels of IL-27 in patients with Parkinson disease and their correlation with disease severity.

TNF IL27

8.69e-062103229408778
Pubmed

STAT6 and Furin Are Successive Triggers for the Production of TGF-β by T Cells.

STAT6 FURIN

8.69e-062103230266770
Pubmed

Transcription factor Fli-1 positively regulates lipopolysaccharide-induced interleukin-27 production in macrophages.

FLI1 IL27

8.69e-062103226900987
Pubmed

Impact of IL-27p28 (rs153109) and TNF-α (rs1800629) Genetic Polymorphisms on the Progression of HCV Infection in Egyptian Patients.

TNF IL27

8.69e-062103230204505
Pubmed

Epigenetic regulation of tumor necrosis factor α (TNFα) release in human macrophages by HIV-1 single-stranded RNA (ssRNA) is dependent on TLR8 signaling.

TLR8 TNF

8.69e-062103222393042
Pubmed

Measurement of transporter associated with antigen processing 1 and tumor necrosis factor alpha expression in hepatitis B virus-related hepatocellular carcinoma and peritumor cirrhosis tissues using tissue chip technology.

TNF TAP1

8.69e-062103223682387
Pubmed

Decreased expression of ryanodine receptors alters calcium-induced calcium release mechanism in mdx duodenal myocytes.

RYR2 RYR3

8.69e-062103214985349
Pubmed

Suppression of TNF-α and IL-1 signaling identifies a mechanism of homeostatic regulation of macrophages by IL-27.

TNF IL27

8.69e-062103220971923
Pubmed

Cytoskeletal scaffolding proteins interact with Lynch-Syndrome associated mismatch repair protein MLH1.

ABCC3 GSTP1 FCGBP PARVA

2.37e-0556103420706999
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

ABCC3 GBF1 ITPRIPL2 KHNYN TSC2 FRYL PLEKHG5 FOCAD URB1 ARHGEF40 FURIN GCN1 SCARA3

2.38e-0511051031335748872
Pubmed

Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects.

ABCC3 ABCC6 GSTP1 SLC22A8 TAP1 ABCG5

2.47e-05193103619343046
Pubmed

Type 1 and type 3 ryanodine receptors are selectively involved in muscarinic antinociception in mice: an antisense study.

RYR2 RYR3

2.60e-053103218403125
Pubmed

Control of Neuronal Ryanodine Receptor-Mediated Calcium Signaling by Calsenilin.

RYR2 RYR3

2.60e-053103229730765
Pubmed

Memory type 2 helper T cells induce long-lasting antitumor immunity by activating natural killer cells.

STAT6 KMT2A

2.60e-053103221646476
Pubmed

The ryanodine receptor/calcium channel genes are widely and differentially expressed in murine brain and peripheral tissues.

RYR2 RYR3

2.60e-05310327876312
Pubmed

Variants in the genes encoding TNF-α, IL-10, and GSTP1 influence the effect of α-tocopherol on inflammatory cell responses in healthy men.

GSTP1 TNF

2.60e-053103222572643
Pubmed

Tgfβ-Smad and MAPK signaling mediate scleraxis and proteoglycan expression in heart valves.

SCX FBN1

2.60e-053103224157418
Pubmed

Bidirectional coupling between ryanodine receptors and Ca2+ release-activated Ca2+ (CRAC) channel machinery sustains store-operated Ca2+ entry in human T lymphocytes.

RYR2 RYR3

2.60e-053103222948152
Pubmed

Developmental changes in expression of the three ryanodine receptor mRNAs in the mouse brain.

RYR2 RYR3

2.60e-053103210788707
Pubmed

TLR-8, TNF-α, and ESR-1α Gene Polymorphism Susceptibility in Onset of Arthritis.

TLR8 TNF

2.60e-053103236262248
Pubmed

A novel class of ligand-gated ion channel is activated by Zn2+.

GALR2 ZACN

2.60e-053103212381728
Pubmed

Ca(2+)-induced Ca2+ release in myocytes from dyspedic mice lacking the type-1 ryanodine receptor.

RYR2 RYR3

2.60e-05310327621815
Pubmed

The genomic and clinical landscape of fetal akinesia.

RYR3 GCN1

2.60e-053103231680123
Pubmed

Monocytes maintain central nervous system homeostasis following helminth-induced inflammation.

STAT6 TNF

2.60e-053103236070344
Pubmed

Molecular identification of the ryanodine receptor pore-forming segment.

RYR2 RYR3

2.60e-053103210473538
Pubmed

Protein phosphatase 4 interacts with and down-regulates insulin receptor substrate 4 following tumor necrosis factor-alpha stimulation.

IRS4 TNF

2.60e-053103215331607
Pubmed

Identification of amino acid sequence motifs in desmocollin, a desmosomal glycoprotein, that are required for plakoglobin binding and plaque formation.

JUP GJB1

2.60e-05310327971964
Pubmed

Heterogeneous gene expression and functional activity of ryanodine receptors in resistance and conduit pulmonary as well as mesenteric artery smooth muscle cells.

RYR2 RYR3

2.60e-053103218434746
Pubmed

Genome-wide methylation profiling in Crohn's disease identifies altered epigenetic regulation of key host defense mechanisms including the Th17 pathway.

TNF IL27

2.60e-053103222021194
Pubmed

Influence of polymorphisms in VEGF, TNF-α, and GSTP1 genes on retinopathy of prematurity risk: a Meta-analysis.

GSTP1 TNF

2.60e-053103232264735
Pubmed

Recovery from spinal cord injury in tumor necrosis factor-alpha, signal transducers and activators of transcription 4 and signal transducers and activators of transcription 6 null mice.

STAT6 TNF

2.60e-053103217301687
Pubmed

SPRY domains in ryanodine receptors (Ca(2+)-release channels).

RYR2 RYR3

2.60e-05310329204703
Pubmed

Ryanodine receptors are expressed in epidermal keratinocytes and associated with keratinocyte differentiation and epidermal permeability barrier homeostasis.

RYR2 RYR3

2.60e-053103221881589
Pubmed

Targeted ablation of Abcc1 or Abcc3 in Abcc6(-/-) mice does not modify the ectopic mineralization process.

ABCC3 ABCC6

2.60e-053103217845218
Pubmed

Distribution of furin, TNF-α, and TGF-β2 in the endometrium of missed abortion and voluntary first trimester termination cases.

FURIN TNF

2.60e-053103226065233
Pubmed

Interactions between glutathione S-transferase P1, tumor necrosis factor, and traffic-related air pollution for development of childhood allergic disease.

GSTP1 TNF

2.60e-053103218709160
Pubmed

Isoform-dependent formation of heteromeric Ca2+ release channels (ryanodine receptors).

RYR2 RYR3

2.60e-053103212213830
Pubmed

Predictive potential of ABCB1, ABCC3, and GSTP1 gene polymorphisms on osteosarcoma survival after chemotherapy.

ABCC3 GSTP1

2.60e-053103224996541
Pubmed

Upregulation of tumor necrosis factor α and ADAMTS-5, but not ADAMTS-4, in human intervertebral cartilage endplate with modic changes.

ADAMTS5 TNF

2.60e-053103224732836
Pubmed

Expression of the ryanodine receptor type 3 calcium release channel during development and differentiation of mammalian skeletal muscle cells.

RYR2 RYR3

2.60e-05310329242641
Pubmed

RYR2 proteins contribute to the formation of Ca(2+) sparks in smooth muscle.

RYR2 RYR3

2.60e-053103215024040
Pubmed

Calcineurin upregulates local Ca(2+) signaling through ryanodine receptor-1 in airway smooth muscle cells.

RYR2 RYR3

2.60e-053103225239916
Pubmed

Synergy of IL-27 and TNF-α in regulating CXCL10 expression in lung fibroblasts.

TNF IL27

2.60e-053103223333920
Pubmed

A gene-specific cerebral types 1, 2, and 3 RyR protein knockdown induces an antidepressant-like effect in mice.

RYR2 RYR3

2.60e-053103218643873
Pubmed

Identification of mutations in the cardiac ryanodine receptor gene in families affected with arrhythmogenic right ventricular cardiomyopathy type 2 (ARVD2).

RYR2 RYR3

2.60e-053103211159936
Pubmed

Impaired Toll-like receptor 8-mediated IL-6 and TNF-alpha production in antigen-presenting cells from patients with X-linked agammaglobulinemia.

TLR8 TNF

2.60e-053103217090647
Pubmed

Associations of tumor necrosis factor G-308A with childhood asthma and wheezing.

GSTP1 TNF

2.60e-053103216456144
Pubmed

Prospective tracing of MLL-FRYL clone with low MEIS1 expression from emergence during neuroblastoma treatment to diagnosis of myelodysplastic syndrome.

FRYL KMT2A

2.60e-053103218195096
Pubmed

Interaction between early maternal smoking and variants in TNF and GSTP1 in childhood wheezing.

GSTP1 TNF

2.60e-053103220210814
Pubmed

Chromosomal localization of murine ryanodine receptor genes RYR1, RYR2, and RYR3 by in situ hybridization.

RYR2 RYR3

2.60e-05310327959768
Pubmed

The organization of proteins in the human red blood cell membrane. A review.

RYR2 RYR3

2.60e-05310324600883
Pubmed

Regulation of mouse egg activation: presence of ryanodine receptors and effects of microinjected ryanodine and cyclic ADP ribose on uninseminated and inseminated eggs.

RYR2 RYR3

2.60e-05310327635066
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

IRS4 GBF1 MYO9A PSMD7 TSC2 FRYL JUP SYNJ2 KMT2A MTREX PPIP5K2

5.06e-058611031136931259
Pubmed

Paraxis: a basic helix-loop-helix protein expressed in paraxial mesoderm and developing somites.

TCF15 SCX

5.19e-05410327729571
Pubmed

ACAT2 and ABCG5/G8 are both required for efficient cholesterol absorption in mice: evidence from thoracic lymph duct cannulation.

ABCG5 SOAT2

5.19e-054103222669916
Pubmed

Polymorphisms in HLA-related genes and psoriasis heredity in patients with psoriasis.

TNF TAP1

5.19e-054103223834030
Pubmed

IL-4-Stat6 signaling induces tristetraprolin expression and inhibits TNF-alpha production in mast cells.

STAT6 TNF

5.19e-054103214638848
Pubmed

Ryanodine receptor calcium release channels: lessons from structure-function studies.

RYR2 RYR3

5.19e-054103223413940
Pubmed

Associations between second-trimester amniotic fluid levels of ADAMTS4, ADAMTS5, IL-6, and TNF-α and spontaneous preterm delivery in singleton pregnancies.

ADAMTS5 TNF

5.19e-054103230730845
Pubmed

A role for T helper 2 cells in mediating skin fibrosis in tight-skin mice.

STAT6 FBN1

5.19e-054103210486156
Pubmed

Recombinant protein glutathione S-transferases P1 attenuates inflammation in mice.

GSTP1 TNF

5.19e-054103218962899
Pubmed

Partial cloning and differential expression of ryanodine receptor/calcium-release channel genes in human tissues including the hippocampus and cerebellum.

RYR2 RYR3

5.19e-05410329607712
Pubmed

Conserved and divergent functions of Nfix in skeletal muscle development during vertebrate evolution.

RYR2 RYR3

5.19e-054103223482488
Pubmed

A glutathione deficit alters dopamine modulation of L-type calcium channels via D2 and ryanodine receptors in neurons.

RYR2 RYR3

5.19e-054103218206662
Pubmed

Clustering of Genetic Anomalies of Cilia Outer Dynein Arm and Central Apparatus in Patients with Transposition of the Great Arteries.

DNAH9 DNAH11

5.19e-054103236140829
Pubmed

Bruton's tyrosine kinase regulates TLR7/8-induced TNF transcription via nuclear factor-κB recruitment.

TLR8 TNF

5.19e-054103229567473
Pubmed

Integration of CREB and bHLH transcriptional signaling pathways through direct heterodimerization of the proteins: role in muscle and testis development.

TCF15 SCX

5.19e-054103218361414
Pubmed

Expression of pro-inflammatory TACE-TNF-α-amphiregulin axis in Sjögren's syndrome salivary glands.

FURIN TNF

5.19e-054103220811902
Pubmed

Requirement for the ryanodine receptor type 3 for efficient contraction in neonatal skeletal muscles.

RYR2 RYR3

5.19e-05410329384575
Pubmed

IL-27 Limits Type 2 Immunopathology Following Parainfluenza Virus Infection.

STAT6 IL27

5.19e-054103228129374
Pubmed

Tumor necrosis factor alpha production from CD8+ T cells mediates oviduct pathological sequelae following primary genital Chlamydia muridarum infection.

TNF TAP1

5.19e-054103221536799
Pubmed

Replication of genetic association studies in asthma and related phenotypes.

STAT6 GSTP1 TNF

6.24e-0526103320395963
Pubmed

A transporter associated with antigen-processing independent vacuolar pathway for the MHC class I-mediated presentation of endogenous transmembrane proteins.

FURIN TAP1

8.64e-055103217548631
Pubmed

Presenilins regulate calcium homeostasis and presynaptic function via ryanodine receptors in hippocampal neurons.

RYR2 RYR3

8.64e-055103223918386
Pubmed

Protein kinase C-epsilon regulates local calcium signaling in airway smooth muscle cells.

RYR2 RYR3

8.64e-055103219011160
Pubmed

Extracellular signal-regulated kinase regulation of tumor necrosis factor-alpha mRNA nucleocytoplasmic transport requires TAP-NxT1 binding and the AU-rich element.

TNF TAP1

8.64e-055103218048358
Pubmed

Sorcin is an early marker of neurodegeneration, Ca2+ dysregulation and endoplasmic reticulum stress associated to neurodegenerative diseases.

RYR2 RYR3

8.64e-055103233060591
Pubmed

DNAH11 Localization in the Proximal Region of Respiratory Cilia Defines Distinct Outer Dynein Arm Complexes.

DNAH9 DNAH11

8.64e-055103226909801
Pubmed

Novel alleles at the lymphotoxin alpha (LTalpha) locus mark extended HLA haplotypes in native Africans.

TNF TAP1

8.64e-055103211250044
Pubmed

Inhibition of Hematopoietic Cell Kinase Activity Suppresses Myeloid Cell-Mediated Colon Cancer Progression.

STAT6 TNF

8.64e-055103228399411
Pubmed

Interleukin-4 downregulates TNFalpha-induced IL-8 production in keratinocytes.

STAT6 TNF

8.64e-055103216004996
Pubmed

[The expression of Toll-like receptor 8 and cytokines in rheumatoid arthritis mice induced by chicken II collogen].

TLR8 TNF

8.64e-055103219351498
InteractionFPR1 interactions

DMXL2 GBF1 TUBGCP2 FANCD2 URB1 RARS2 GCN1

7.07e-06147977int:FPR1
InteractionNPY2R interactions

DMXL2 GBF1 TUBGCP2 RARS2 GCN1

1.65e-0566975int:NPY2R
CytobandEnsembl 112 genes in cytogenetic band chr17q25

SDK2 FADS6 GALR2 ZACN RECQL5 DNAH17 FSCN2

6.39e-063071037chr17q25
Cytoband1q44

OR2T29 OR2T35 OR2T5 OR2T6

1.15e-0411010341q44
CytobandEnsembl 112 genes in cytogenetic band chr1q44

OR2T29 OR2T35 OR2T5 OR2T6

2.06e-041281034chr1q44
Cytoband17q25.3

GALR2 ZACN DNAH17

1.56e-03101103317q25.3
CytobandXq22.3

IRS4 MORC4

2.52e-03331032Xq22.3
GeneFamilyDyneins, axonemal

DNAH17 DNAH9 DNAH11

4.65e-0517763536
GeneFamilyRyanodine receptors|Protein phosphatase 1 regulatory subunits

RYR2 RYR3

5.22e-053762287
GeneFamilyOlfactory receptors, family 2

OR2T29 OR2T35 OR2T5 OR2T6 OR2AT4

1.13e-04113765149
GeneFamilyBasic helix-loop-helix proteins

TCF15 TCF21 SCX TCF24

1.19e-03110764420
GeneFamilyATP binding cassette subfamily C

ABCC3 ABCC6

1.32e-0313762807
ToppCell-Unknown-Endothelial-Myofibroblast| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MYO9A HPSE2 ADAMTS5 RYR2 TCAIM KMT2A RARS2

2.81e-0718810376468fa95ad0395395301115286f2d8c0df5d3882
ToppCell-Unknown-Endothelial| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MYO9A HPSE2 ADAMTS5 RYR2 TCAIM KMT2A RARS2

2.81e-0718810377a81ac5c79c3eb26639b52d2b9fd5e7ef9798fd6
ToppCell-Unknown| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MYO9A HPSE2 ADAMTS5 RYR2 TCAIM KMT2A RARS2

2.81e-0718810379cb718bfe1358c6fd842f096e228eb0abb9aefc6
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6_CT-L6_CT_VISp_Krt80_Sla|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SDK2 ADAMTS5 RYR3 FANCD2 JUP TPBG

1.41e-061511036f50c5ae9dae507df750df25e151b58685fec70ce
ToppCellfacs-Marrow-KLS-18m-Lymphocytic-BM_CD4_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCF21 GALR2 TLR8 TCAIM SLC38A6 SOAT2

2.45e-061661036aa2df07eff323ded751ced8938af08223d7f2029
ToppCellfacs-Marrow-KLS-18m-Lymphocytic-CD4-positive,_alpha-beta_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCF21 GALR2 TLR8 TCAIM SLC38A6 SOAT2

2.45e-061661036695298a94d62b8adab083900003ec636fbaae5d9
ToppCellfacs-Diaphragm-Limb_Muscle-24m|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZAN RYR2 RYR3 KCNH4 DNAH9 DNAH11

2.72e-06169103612bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FLI1 NPY1R TCF21 HPSE2 FBN1 DAAM2

5.33e-0619010362306aa9dbeaef3be8484a5b236605de23cd75d4c
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FLI1 NPY1R TCF21 HPSE2 FBN1 DAAM2

5.33e-0619010361f83f7f24288a3b9ab33c2e113e845dba96adc8a
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FLI1 NPY1R TCF21 HPSE2 FBN1 DAAM2

5.50e-061911036a58c75e9580139fb370b498d95660f10f3a2a27b
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FLI1 NPY1R TCF21 HPSE2 FBN1 DAAM2

5.66e-0619210369093a9e94a25682d109a7f6edc256a25a61103a0
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FLI1 NPY1R TCF21 HPSE2 FBN1 DAAM2

5.66e-0619210369ed5d49621ec1aa01716dc369bba1450b5f015f5
ToppCellLPS-IL1RA-Stromal_mesenchymal|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SDK2 TCF21 RYR2 FBN1 DAAM2 SCARA3

5.66e-0619210364e47a02007f562f29ba5910df64d32a0167d0bd1
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC3 MYO9A KIF12 GSTP1 FCGBP TPBG

6.95e-0619910362e7f517c0444b4f29ff11c26ab32e9cc0f7e99ef
ToppCellControl_saline-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast|Control_saline / Treatment groups by lineage, cell group, cell type

HPSE2 ADAMTS5 SCX RYR2 FBN1 SCARA3

7.15e-062001036c5e051f1aac8dda376c342a9932785a23450e073
ToppCellControl_saline-Mesenchymal_myocytic-Myofibroblastic|Control_saline / Treatment groups by lineage, cell group, cell type

HPSE2 ADAMTS5 SCX RYR2 FBN1 SCARA3

7.15e-0620010369d5b3c2dcfa55d50acc2ce2c319d51aa525d4cd1
ToppCellControl_saline-Mesenchymal_myocytic|Control_saline / Treatment groups by lineage, cell group, cell type

HPSE2 ADAMTS5 RYR2 FBN1 DAAM2 SCARA3

7.15e-0620010365ed4261157cd51109b314818133ac3a0d34ee5fa
ToppCellLPS_anti-TNF-Mesenchymal_myocytic|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

HPSE2 ADAMTS5 RYR2 FBN1 DAAM2 SCARA3

7.15e-06200103667dcbd86fbc79fd585d0793f979e4aac100326c9
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6b-L6b_VISp_Col8a1_Rxfp1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SDK2 FANCD2 JUP ZDHHC12 TPBG

1.35e-05131103581efe8b0ca4377e557a42ddb12aecaf3f46b15bf
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6b-L6b_VISp_Col8a1_Rprm|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SDK2 RYR3 FANCD2 JUP ZDHHC12

1.40e-05132103566ec5a06eece27c0aafb548f51db9fee595e71bc
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L6b|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SDK2 FANCD2 JUP ZDHHC12 TPBG

1.86e-05140103517005ca714ba03d7528fe7979ffb4654a46b666c
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6b|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SDK2 FANCD2 JUP ZDHHC12 TPBG

1.93e-0514110355ef3166c5271aa90fd0633016edfe2c74b835319
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L6_CT-L6_CT_ALM_Cpa6|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SDK2 TCF15 FANCD2 JUP ZDHHC12

2.94e-05154103512cbc38bc1f7231c67e1d2d5e86e95bc12e24682
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC3 OR2T29 MYO9A RYR3 RANBP17

3.97e-0516410351cb5fbd7050650047ad6f2ca792118e98d58d22b
ToppCellfacs-Trachea-nan-18m-Mesenchymal-chondrocyte|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITGA10 GALR2 DAAM2 SCARA3 SLC38A3

4.33e-0516710357b1fd19946cee67dae68f0f0d98420abcd532482
ToppCellAdult-Mesenchymal-myofibroblast_cell|Adult / Lineage, Cell type, age group and donor

SDK2 HPSE2 FBN1 SYNJ2 FSCN2

4.33e-051671035d584a8548a5317bd9686b3be8246ae6ed568796b
ToppCellfacs-Trachea-18m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l34|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SDK2 ITGA10 GALR2 SCARA3 SLC38A3

4.33e-051671035102b3d160a44c8623fab1fd10e9054178c42a78b
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MYO9A FCGBP DNAH17 SCARA3 DNAH11

4.71e-0517010355d5f208682be21ed58320f5fc083a7898f8712da
ToppCellfacs-Brain_Myeloid-Cerebellum-3m-Myeloid-nan|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITPRIPL2 MYO9A TUT7 TMEM87A SOAT2

5.12e-051731035869da6a65d1b9b7529c666ec44e3c8ddec2ea408
ToppCellfacs-Brain_Myeloid-Cerebellum-3m-Myeloid|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITPRIPL2 MYO9A TUT7 TMEM87A SOAT2

5.12e-0517310350672bd8a4a9d18af343d01f09253fb3388896c10
ToppCellfacs-Brain_Myeloid-Cerebellum-3m|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITPRIPL2 MYO9A TUT7 TMEM87A SOAT2

5.12e-051731035870e091ec30be01a900e1cb8b9ef1880e3b7b50d
ToppCellfacs-Diaphragm-Limb_Muscle-24m-Mesenchymal|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RYR2 RYR3 KCNH4 GSTP1 DNAH9

5.12e-05173103566f37c1437705734b20601656fa4aa1d92ca30be
ToppCellfacs-Diaphragm-Limb_Muscle-24m-Mesenchymal-nan|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RYR2 RYR3 KCNH4 GSTP1 DNAH9

5.12e-051731035649b08a409095592cccf31883be69c754411280d
ToppCellfacs-Marrow-KLS-18m-Lymphocytic-late_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANKRD6 RANBP17 FBN1 OXNAD1 DNAH11

5.56e-0517610353766e0533b103ec92ac75eba3df02e287efc53fa
ToppCellfacs-Trachea-24m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l34|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SDK2 ITGA10 GALR2 SCARA3 SLC38A3

5.56e-05176103577c3da2eaa072a6baefb5087fd07ec18c5e271cd
ToppCellfacs-Marrow-KLS-18m-Lymphocytic-late_pro_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANKRD6 RANBP17 FBN1 OXNAD1 DNAH11

5.56e-051761035aa1bada2175d8370fc71939a607407155259d195
ToppCelldroplet-Liver-LIVER_HEP-30m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO9A KIF12 SCX DNAH17 SCARA3

5.56e-0517610355e46a09a36b9645b1b1fcb0b64bd0898561af3a9
ToppCell5'-Adult-Distal_Rectal-Epithelial-goblet-Goblet_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DMXL2 TSC2 SCX RANBP17 FCGBP

5.71e-051771035e1e45956887371b1c18f1eb479dd930031497520
ToppCelldroplet-Liver-LIVER_HEP-30m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO9A KIF12 SCX DNAH17 SCARA3

5.71e-05177103514fb8d182775dfd0e49aa7e4e12543a85b3b8bd6
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_FAM95C|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SDK2 ANKRD6 RYR3 SYNJ2 SCARA3

5.86e-051781035431e7557b8e8764e16e9e48368ce6bfa3c61561a
ToppCell5'-Adult-Distal_Rectal-Epithelial-goblet|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CAPN9 TSC2 PLEKHG5 FCGBP OR8D4

5.86e-0517810359099b47e0756d6a1b7ba1c6aa7b47c5425f649e0
ToppCell(5)_Epithelial_cells-(5)_Glands_mucous|(5)_Epithelial_cells / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)

CAPN9 NPY1R RYR2 GJB1 FCGBP

6.18e-051801035a4118adaf4b09e2ca01b662ed60e7bbf32a24d58
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_FAM95C|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SDK2 NPY1R RYR3 SYNJ2 SCARA3

6.18e-051801035b514c55e52b46e8a1a2f09ed2c59a7683367a505
ToppCellChildren_(3_yrs)-Mesenchymal-myofibroblast_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

ITGA10 HPSE2 FBN1 DAAM2 SCARA3

6.18e-05180103501f2e5d96016823482f89ba503d007d4bd88eeac
ToppCellFetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ITGA10 HPSE2 ADAMTS5 RYR3 SCARA3

6.34e-05181103525915e2500430a902db37d79a749ce2990b69810
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SDK2 HPSE2 RYR2 FBN1 SCARA3

6.34e-051811035b116c68393d8836bac080f81a8fcbeb52e0403e7
ToppCell10x3'2.3-week_12-13-Mesenchymal_osteo-stroma-osteoblast|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

SDK2 ITGA10 PANX3 SLC38A3 TPBG

6.51e-051821035193cb2df3d7ea4cb9a11390b92955e7d9b0a053a
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HPSE2 ADAMTS5 RYR2 DAAM2 SCARA3

6.68e-0518310357eae9b3b4d1c9b135fa7cff348393d4adec474b4
ToppCelldroplet-Lung-30m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TCF15 ADAMTS5 MORC4 FBN1 SCARA3

6.68e-051831035351d575339038bd4a66f408da518c567444208e8
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZAN RYR2 RYR3 DNAH9 DNAH11

6.86e-0518410352cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZAN RYR2 RYR3 DNAH9 DNAH11

6.86e-051841035ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZAN RYR2 RYR3 DNAH9 DNAH11

6.86e-0518410352b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1-D122|Adult / Lineage, Cell type, age group and donor

CAPN9 GPR39 ABCC6 RANBP17 PARVA

6.86e-051841035561592edc3083fad41b91811151b442207c65dd9
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_Arw_fibro_(16)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

ADAMTS5 RYR2 RYR3 FBN1 TPBG

7.04e-0518510357dcdc009c5681ee05dd18968f7e85c3403fe34af
ToppCellControl-Epithelial-Club|Epithelial / Disease state, Lineage and Cell class

ABCC3 TUT7 JUP FBN1 SYNJ2

7.04e-0518510356814b3c94c7558443c038a227b5c8563d2cfeac4
ToppCelldroplet-Lung-18m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l39|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NPY1R TMEM63C HPSE2 ADAMTS5 SCARA3

7.40e-051871035218c9b4f28499389c43005d9626af2ac01066027
ToppCelldroplet-Lung-18m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NPY1R TMEM63C HPSE2 ADAMTS5 SCARA3

7.40e-051871035c7ac4b328efc2ebb72f71154661914193ff402ca
ToppCellLPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HPSE2 ADAMTS5 SCX RYR2 SCARA3

7.59e-0518810353177b2c1723268d330d3e9f24f9e24492ace6286
ToppCelldroplet-Lung-nan-18m-Mesenchymal-Airway_Smooth_Muscle|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NPY1R TMEM63C HPSE2 RYR2 SCARA3

7.59e-05188103561f010c165826b434ca3d27553d4c9e13d2c0c51
ToppCelldroplet-Lung-nan-18m-Mesenchymal-bronchial_smooth_muscle_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NPY1R TMEM63C HPSE2 RYR2 SCARA3

7.59e-0518810357553ef7de3575af4cf34704b405b551c1af8eb83
ToppCellFetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

HPSE2 ADAMTS5 SCX RYR3 SCARA3

7.59e-0518810354d1e5f85342ae550086609d7680e32730b78b5d2
ToppCellMesenchymal-chondrocyte|World / Lineage, Cell type, age group and donor

SDK2 ITGA10 FBN1 DAAM2 SCARA3

7.59e-0518810357b1e3f8a941eaa68e89c562129a92314642eec66
ToppCelldroplet-Lung-LUNG-1m-Mesenchymal-adventitial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR39 ADAMTS5 FBN1 SCARA3 ABCG5

7.78e-051891035f0a2d4ef9896d764971ebbc6952510c128bb76e8
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HPSE2 ADAMTS5 RYR2 DAAM2 SCARA3

7.78e-0518910357ab1cfc1657277858339f7258a0c4ae9cb42fdf8
ToppCelldroplet-Lung-LUNG-1m-Mesenchymal-Adventitial_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR39 ADAMTS5 FBN1 SCARA3 ABCG5

7.78e-051891035378f26f751ab4b470948c35dd8347de72dd12ff7
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HPSE2 ADAMTS5 RYR2 DAAM2 SCARA3

7.78e-05189103545e588b2a4ad9e3ff74e22d9d627ed3571f3b8b8
ToppCellControl-Stromal_mesenchymal|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HPSE2 ADAMTS5 RYR2 DAAM2 SCARA3

8.18e-05191103514057205ddb9b4bbc582d1358d13cf36d979a61b
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HPSE2 ADAMTS5 SCX RYR2 SCARA3

8.18e-051911035b133ee1c0e58d00ddd2e4e05b01fd04947524c18
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HPSE2 ADAMTS5 RYR2 DAAM2 SCARA3

8.38e-051921035992d08092edbc68c47b945deb8708379738c239a
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SDK2 TCF21 RYR2 FBN1 SCARA3

8.38e-051921035f4fc2b0121f879bab2bee99dfb5ff2c3ca1c0e1b
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NPY1R ITGA10 HPSE2 ADAMTS5 SCARA3

8.38e-05192103526d9207e72bbef5e0046de511e2c9ff752b726f3
ToppCell5'-GW_trimst-2-SmallIntestine-Epithelial-goblet|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CAPN9 ABCC3 KIF12 FRYL FCGBP

8.59e-051931035402aad2f9e789ad1f2e1536cdc9ce61de7625427
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FLI1 NPY1R HPSE2 FBN1 DAAM2

8.59e-051931035f1199518c3626fd29bfce65070dd21a660671213
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NPY1R ITGA10 HPSE2 ADAMTS5 SCARA3

8.59e-0519310357fc3ab7261c88c1df71744bf5b17e8e46c4300e0
ToppCell5'-GW_trimst-2-SmallIntestine-Epithelial-goblet-Goblet_cell|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CAPN9 ABCC3 KIF12 FRYL FCGBP

8.59e-0519310357ee3b1ef5c455f321b4e154ae62c69543fe9b30e
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ITGA10 HPSE2 SCX DAAM2 SCARA3

8.80e-0519410358fae8061b350336299aa81f378e07deadbd55123
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SDK2 TCF21 HPSE2 RYR2 FBN1

8.80e-051941035011e14d9ed1393275f892060e7708ffadcd0767f
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NPY1R TCF21 HPSE2 FBN1 DAAM2

8.80e-051941035240d122dcb9dd1ab2867503ad85869853adcacae
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NPY1R TCF21 HPSE2 FBN1 DAAM2

8.80e-051941035ae7df037592f1c20c9d32be15fe6fc3c562ebeb1
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ITGA10 HPSE2 SCX DAAM2 SCARA3

8.80e-0519410354d7d24390fdb379f943ddcc70a63f23955e10163
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NPY1R TCF21 HPSE2 FBN1 DAAM2

9.01e-051951035d8ebb94f30d4a655d6b29dd6a3076be2403d2356
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NPY1R TCF21 HPSE2 FBN1 DAAM2

9.01e-05195103544d7bef5f59c2c2bad1392ee6aabdaa5d7f531d9
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FLI1 NPY1R HPSE2 FBN1 DAAM2

9.23e-051961035a12dd986df65c36f248cf10815c3b8b6238613b0
ToppCellMesenchymal_cells-Fibro/Chondro_p.|World / Lineage and Cell class

SDK2 ITGA10 GALR2 SCX SCARA3

9.23e-051961035ddc168849e0e97005a111be004463bb72d433853
ToppCellfacs-Heart-LA-3m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCF21 ADAMTS5 ARHGEF40 FBN1 SCARA3

9.23e-051961035ad1838dabd043cb140260843e3527d8c7d58850e
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NPY1R TCF21 HPSE2 FBN1 DAAM2

9.23e-051961035ba869f7a86f37fd6d84d6ad69baca0e0faaf5887
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NPY1R TCF21 HPSE2 FBN1 DAAM2

9.23e-05196103530ad56d49000e4ddce73b4443b3994564bd1e2d6
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FLI1 NPY1R HPSE2 FBN1 DAAM2

9.23e-0519610353e6803587d8566fd08cb8b290be3b6461743d79c
ToppCellfacs-Heart-LA-3m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCF21 ADAMTS5 ARHGEF40 FBN1 SCARA3

9.23e-051961035cbc15c0769016fe9972445169029bd8d14a7e6ef
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FLI1 NPY1R HPSE2 FBN1 DAAM2

9.46e-0519710356d027119a5f7ca2aac1b10837e43f9a2bb54db85
ToppCellfacs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SDK2 ITGA10 GALR2 SCARA3 SLC38A3

9.46e-0519710354b6c0e028b9669c102df8e9dc63e284f8d5fd9ee
ToppCellfacs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l1|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

GALR2 SCX DAAM2 SCARA3 TPBG

9.46e-0519710353fe665c0277d091290b63f0dd24c0c6536a45309
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FLI1 NPY1R HPSE2 FBN1 DAAM2

9.46e-051971035b349f8e96d61a4c296af64711e11fc44459a9413
ToppCell10x3'2.3-week_12-13-Mesenchymal_osteo-stroma|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

ITGA10 PANX3 PARVA SCARA3 TPBG

9.46e-05197103563b63c6b2f842adb87bc83222ff86796bd9b58f6
ToppCellfacs-Trachea-3m-Mesenchymal-myofibroblast|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SDK2 ITGA10 GALR2 SCARA3 SLC38A3

9.46e-051971035ece0c17eb68f394b20e588c0b0626d3987a4dbbb
ToppCell10x3'2.3-week_12-13-Mesenchymal_osteo|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

ITGA10 PANX3 PARVA SCARA3 TPBG

9.46e-051971035fb50903b87498b400c8e16e6a561b6d9458e5d97
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FLI1 NPY1R HPSE2 FBN1 DAAM2

9.46e-051971035c2e390653d5dee7e731c1840cfdab41987dede9b
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TCF21 HPSE2 ADAMTS5 FBN1 DAAM2

9.69e-05198103509be07ebfc3e49c3858e9b74605b69cf4fc28b56
ToppCellTracheal-10x5prime-Stromal-Chondrocytic|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

SDK2 ITGA10 SLC22A8 DAAM2 SCARA3

9.69e-051981035c72ef2ddcbb6dacbed4c6200d89e17d57314dcdc
ToppCell3'-GW_trimst-1-LargeIntestine-Epithelial-epithelial_progenitor_cell-TA|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ABCC3 KIF12 GSTP1 GJB1 ZDHHC12

9.69e-0519810352ada078be27588ab46f2d4e53d20f8e9bc8761df
DrugCholates

ABCC3 SLC22A8 TNF ABCG5

8.98e-07171034ctd:D020355
Drug(+)-Isoproterenol (+)-bitartrate salt [14638-70-1]; Up 200; 11uM; MCF7; HT_HG-U133A

CAPN9 ABCC3 STAT6 GSTP1 FBN1 SYNJ2 FURIN SCARA3

3.21e-0619710385009_UP
DrugDoxycycline

ABCC3 CCNG2 GSTP1 TNF ABCG5

7.70e-06601035ctd:D004318
DrugGsts

ABCC3 ZAN GALR2 ABCC6 GSTP1 SLC38A6 GPR148

1.39e-051731037CID000128079
Drugtrimethylarsine oxide

ABCC3 GSTP1 GJB1 TNF

1.46e-05331034ctd:C052920
Diseaseextrinsic allergic alveolitis (is_implicated_in)

TNF TAP1

9.83e-062932DOID:841 (is_implicated_in)
Diseasemucopolysaccharidosis VI (biomarker_via_orthology)

ADAMTS5 TNF

2.94e-053932DOID:12800 (biomarker_via_orthology)
Diseasecongenital myopathy 1A (implicated_via_orthology)

RYR2 RYR3

2.94e-053932DOID:3529 (implicated_via_orthology)
Diseasemalignant hyperthermia (implicated_via_orthology)

RYR2 RYR3

2.94e-053932DOID:8545 (implicated_via_orthology)
DiseaseCor pulmonale (is_marker_for)

TNF IL27

2.94e-053932DOID:8515 (is_marker_for)
Diseasesystemic scleroderma (implicated_via_orthology)

FLI1 FBN1

2.94e-053932DOID:418 (implicated_via_orthology)
Diseasecervical cancer (is_implicated_in)

KMT2A TNF TAP1

1.16e-0430933DOID:4362 (is_implicated_in)
Diseasecoronary artery disease (is_implicated_in)

TCF21 ABCC6 TNF SOAT2

2.88e-04100934DOID:3393 (is_implicated_in)
Diseasepulmonary tuberculosis (is_implicated_in)

TNF TAP1 IL27

3.18e-0442933DOID:2957 (is_implicated_in)
Diseasecholestasis (biomarker_via_orthology)

ABCC3 GSTP1 ABCG5

5.03e-0449933DOID:13580 (biomarker_via_orthology)
Diseasetuberculosis (is_marker_for)

TNF IL27

5.31e-0411932DOID:399 (is_marker_for)
DiseaseDiabetic Cardiomyopathies

RYR2 TNF

5.31e-0411932C0853897
Diseasecorneal resistance factor

FADS6 RANBP17 NPHP3 FBN1 SYNJ2 KMT2A SLC38A6

5.69e-04451937EFO_0010067
Diseaseobesity (implicated_via_orthology)

CAPN9 SDK2 NPY1R GSTP1 JUP

6.06e-04215935DOID:9970 (implicated_via_orthology)
Diseaseopen-angle glaucoma (is_implicated_in)

TNF TAP1

6.35e-0412932DOID:1067 (is_implicated_in)
Diseaseliver disease (is_implicated_in)

GSTP1 TNF

6.35e-0412932DOID:409 (is_implicated_in)
Diseasebronchopulmonary dysplasia (is_implicated_in)

GSTP1 TNF

7.49e-0413932DOID:11650 (is_implicated_in)
DiseaseSarcoma, Spindle Cell

GSTP1 TNF

8.72e-0414932C0205945
DiseaseSarcoma, Epithelioid

GSTP1 TNF

8.72e-0414932C0205944
Diseaseallergic disease (is_implicated_in)

GSTP1 TAP1

1.00e-0315932DOID:1205 (is_implicated_in)
Diseasechronic obstructive pulmonary disease (is_implicated_in)

GSTP1 TNF IL27

1.05e-0363933DOID:3083 (is_implicated_in)
DiseaseChromosome Aberrations

GSTP1 KMT2A

1.15e-0316932C0008625
DiseaseAutosome Abnormalities

GSTP1 KMT2A

1.15e-0316932C0004403
Diseasenon-alcoholic fatty liver disease (biomarker_via_orthology)

ABCC3 TNF ABCG5

1.15e-0365933DOID:0080208 (biomarker_via_orthology)
DiseasePsychoses, Substance-Induced

NPY1R GSTP1

1.30e-0317932C0033941
DiseaseTachycardia

RYR2 TNF

1.45e-0318932C0039231
DiseaseTachyarrhythmia

RYR2 TNF

1.45e-0318932C0080203
Diseaseasthma (is_implicated_in)

GSTP1 TNF TAP1 IL27

1.56e-03157934DOID:2841 (is_implicated_in)
Diseasesensorineural hearing loss (implicated_via_orthology)

DNAH17 DNAH9

1.62e-0319932DOID:10003 (implicated_via_orthology)
DiseasePsychoses, Drug

NPY1R GSTP1

1.98e-0321932C0033937
DiseaseSarcoma

GSTP1 TNF

1.98e-0321932C1261473
Diseaseanxiety disorder (implicated_via_orthology)

NPY1R TSC2

2.18e-0322932DOID:2030 (implicated_via_orthology)
DiseaseBronchiectasis

TNF DNAH11

2.18e-0322932C0006267
DiseaseMyocardial Ischemia

RYR2 GSTP1 TNF TAP1

2.36e-03176934C0151744
DiseaseCoronary heart disease

ABCG5 DNAH11

2.59e-0324932C0010068
DiseaseDyslipidemias

ABCG5 DNAH11

2.59e-0324932C0242339
DiseaseDyslipoproteinemias

ABCG5 DNAH11

2.59e-0324932C0598784
Diseasedescending aortic diameter

STAT6 ARHGEF40 FBN1

2.74e-0388933EFO_0021788
Diseasepre-eclampsia (is_implicated_in)

GSTP1 TNF

2.81e-0325932DOID:10591 (is_implicated_in)
DiseaseFanconi Anemia

FANCD2 TNF

2.81e-0325932C0015625
Diseasebreast cancer (is_marker_for)

LETMD1 TSC2 FANCD2 TNF

2.83e-03185934DOID:1612 (is_marker_for)
DiseaseEdema

STAT6 TNF

3.04e-0326932C0013604
Diseaseanogenital venereal wart (is_marker_for)

TLR8 TNF

3.04e-0326932DOID:11168 (is_marker_for)
Diseaseatopic dermatitis (is_implicated_in)

GSTP1 TNF

3.04e-0326932DOID:3310 (is_implicated_in)
DiseaseAcute monocytic leukemia

FANCD2 KMT2A

3.04e-0326932C0023465
DiseaseEndogenous Hyperinsulinism

FBN1 TNF

3.04e-0326932C1257963
DiseaseExogenous Hyperinsulinism

FBN1 TNF

3.04e-0326932C1257964
DiseaseCompensatory Hyperinsulinemia

FBN1 TNF

3.04e-0326932C1257965
DiseaseAnasarca

STAT6 TNF

3.04e-0326932C0151603

Protein segments in the cluster

PeptideGeneStartEntry
DTLNTTLHYLHSLLR

ARHGEF40

566

Q8TER5
THISALLQYINLSLT

ANAPC4

256

Q9UJX5
LLTLASIANRLYSHA

ADAMTS5

291

Q9UNA0
TTALNFLHLYHTIIL

CCNG2

156

Q16589
LTDRCYITLTQSLHL

DNAH11

1871

Q96DT5
LGRALTAHLYSLLQT

ARFIP2

146

P53365
VYLSLLIHALATNSS

DMXL2

2351

Q8TDJ6
AARYNHLSIIRLLLT

ANKRD6

181

Q9Y2G4
LSVSHSDLLQYRKLS

RANBP17

871

Q9H2T7
ELQLLRTAAYLHTTT

ABCC3

521

O15438
TTILLRTFLNYLLHL

RSPH10B

486

P0C881
TTILLRTFLNYLLHL

RSPH10B2

486

B2RC85
TKSSIDRNISLLHYL

DAAM2

831

Q86T65
ISYAFILTSILRIHS

OR8D4

216

Q8NGM9
TKTHLLSLSSLTYQR

KIAA0100

1411

Q14667
ATLLHVLTLSFERYI

GPR39

121

O43194
LSLLLHNVVLLSTNY

LETMD1

341

Q6P1Q0
HSSILTCTLLLLYSL

MFSD9

356

Q8NBP5
SSRSHALLTLYISRQ

KIF12

226

Q96FN5
SLHAITIFSLSTLLI

TMEM63C

681

Q9P1W3
TIISSSYLLILLTVH

OR2T5

216

Q6IEZ7
FLLSHLSVIDTLYIS

OR2T6

61

Q8NHC8
LLQIIYSLLSHIDLS

FRYL

2201

O94915
LLYIFNITVTSLVHL

KCNH4

321

Q9UQ05
AHLLDLLARLSIYST

TUBGCP2

831

Q9BSJ2
YTSHLRSLVSGLIRL

GCN1

2186

Q92616
LSVISVSYTHILLTV

OR2T35

211

Q8NGX2
ALYLALLLHLSLSSQ

HPSE2

26

Q8WWQ2
SVLFYAITTLHNLLL

JUP

241

P14923
HLLVVSLFYISLSLT

OR10A2

231

Q9H208
TIISSSYLLILLTVH

OR2T29

216

Q8NH02
RSHSLVATYLLRNSL

PANX3

201

Q96QZ0
LRNSLLLIFTSATYL

PANX3

211

Q96QZ0
ISYVNILLAILRIHS

OR9G4

231

Q8NGQ1
ATLLITIYLEASLHQ

OR56A5

46

P0C7T3
LRLTLSTLRHLTLTS

OXNAD1

26

Q96HP4
SHRLSYTTLLLVLQY

NPY1R

206

P25929
LTRATYALRILSHLV

GALR2

266

O43603
VYKSRIQSLHLLFSL

IFT46

251

Q9NQC8
TTIYNTILTQHLAFR

DNAH17

2601

Q9UFH2
RSVTLQIYNHSLTLS

FCGBP

3331

Q9Y6R7
TRSVTLQIYNHSLTL

FCGBP

4531

Q9Y6R7
LPALTTLTNHNRYLI

FBN1

2781

P35555
ITRLEHAQARLTLSY

FURIN

481

P09958
YSRARGTLLIHSVLI

GPR148

256

Q8TDV2
GTLLIHSVLITLYVS

GPR148

261

Q8TDV2
LRATTLYNTEVLLSH

FLI1

176

Q01543
VLLSHLSYLRESSLL

FLI1

186

Q01543
LSTYRLLHSLELVLS

IL27

201

Q8NEV9
LTLYQSNTILRHLGR

GSTP1

61

P09211
SLTVRETLHYTALLA

ABCG5

141

Q9H222
LYTLLSGVNRHSTAI

GJB1

6

P08034
SLSLIFSRNLHLASL

ITGA10

841

O75578
YTTHLLSLDALLTVI

GBF1

571

Q92538
HFLQKLYSLSLLSLT

KHNYN

496

O15037
LLNSRTTSHLLRYRQ

KMT2A

1651

Q03164
DALSSIYSIILTQHL

DNAH9

2621

Q9NYC9
HIQLYNLSISRISFI

FAM135B

1201

Q49AJ0
QLSSHLLQLIVLRYA

CAPN9

626

O14815
FITILSLSYLGRHTT

SLC22A8

371

Q8TCC7
ILAYQITHRLNTTTA

SDK2

1331

Q58EX2
LHTSVRILYLFLALL

SCARA3

51

Q6AZY7
LILVSVSSERYLHLS

RYR2

181

Q92736
HSLSLNTKRYLLISA

FOCAD

1456

Q5VW36
ALRTLALISLGLYSH

FADS6

196

Q8N9I5
LLYSALHVLSSRLKQ

FANCD2

1086

Q9BXW9
SLVLVSYSHILAAIL

OR2A1;

211

Q8NGT9
LSYVHILASVLRISS

OR2AT4

221

A6NND4
LIALIYTHNTLGSLN

MT-ND4

161

P03905
YTHNTLGSLNILLLT

MT-ND4

166

P03905
RSYSISIGAHLLTLL

IRS4

341

O14654
QSHLQRSLATVRYSL

ITPRIPL2

256

Q3MIP1
ISYSLIISSILKIHS

OR13C9

216

Q8NGT0
TAVLLRSSHLGRYLS

FSCN2

56

O14926
LLIPHTRYTLHINTL

ALOX15B

401

O15296
TRYTLHINTLARELL

ALOX15B

406

O15296
IVSYLLTLSHLAAVA

RARS2

521

Q5T160
HTRDLLSTVLYILNS

TCAIM

116

Q8N3R3
VALLSSYSIHLLLKS

SLC38A3

106

Q99624
SRSHRYILLTSAQLV

SYNJ2

616

O15056
RHLSTYLCLSLVVAQ

ABCC6

166

O95255
CQDTLSLYRLVLHSI

NPHP3

741

Q7Z494
YLASLIRSVVALHNL

PSMD7

261

P51665
KLTRLRIHVSYLLTS

MORC4

891

Q8TE76
LLLTVALLASYSVHL

SLC38A6

81

Q8IZM9
RYSRSVLLITQHLSL

TAP1

691

Q03518
SLVAILHLLVALSQY

PARVA

186

Q9NVD7
TYLTAVLTDLLHTQR

URB1

811

O60287
SLIHSSLALRILFYR

OR5L2

156

Q8NGL0
TSYLLILTTILKIHS

OR5L2

216

Q8NGL0
FSTRALVLSILHATL

SOAT2

331

O75908
LHRLQTALSLYSTSL

C12orf4

311

Q9NQ89
TLNSLVSRHLLSYLV

RECQL5

141

O94762
LLLATTYIAHLTRSL

TCF24

91

Q7RTU0
AQLYRIRTTLLLNST

PLEKHG5

986

O94827
LASSYIAHLANVLLL

TCF15

116

Q12870
LTQLRYLNLSSTSLR

TLR8

286

Q9NR97
VLVHLLSAISSVRLY

MTREX

731

P42285
LILVSVSSERYLHLS

RYR3

171

Q15413
LLQALRKTYTISHTS

RYR3

1996

Q15413
TILQHISTLESIYQR

STAT6

76

P42226
LLARSSLSHYLGISL

WDR97

966

A6NE52
LRLASSYIAHLRQIL

TCF21

121

O43680
VTLLLSYLVLHSSLV

ZACN

266

Q401N2
ARILLSIYHTTRLLE

ZSWIM3

301

Q96MP5
LVSLTYVSFRNLTHL

TPBG

246

Q13641
VYSLIQSLTSQIRHR

PPIP5K2

666

O43314
SLVASLLLVSHLYLV

ZDHHC12

191

Q96GR4
LLLVSHLYLVASNTT

ZDHHC12

196

Q96GR4
TLRLASSYISHLGNV

SCX

116

Q7RTU7
SLYNTLALHNTRLLS

TUT7

1121

Q5VYS8
LALHNTRLLSAYSAI

TUT7

1126

Q5VYS8
LLTHTISRIAVSYQT

TNF

151

P01375
VKLSLYRHFTNTLIL

TMEM87A

396

Q8NBN3
SSLLNLISYRAQSIH

TSC2

421

P49815
RVTIRLSSNLVLLYT

ZAN

1636

Q9Y493
YSVIDQLSRTHLNTL

MYO9A

2171

B2RTY4