Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionsemaphorin receptor activity

PLXNA3 PLXNA4 PLXNA1 PLXNB3

9.37e-0812764GO:0017154
GeneOntologyMolecularFunctioncalcium ion binding

NELL1 NID2 FAT4 FBN2 MEGF6 MEGF8 SLIT1 DLL3 DLK1 PLCD1 LRP1B FBN3 NOTCH2 NOTCH4

7.69e-077497614GO:0005509
GeneOntologyMolecularFunctionNotch binding

ATRNL1 DLL3 NOTCH4

1.45e-0427763GO:0005112
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

PLXNA3 P2RX7 GPR62 PKD1 PLXNA4 LRP5 ITGB2 PTGIR PLXNA1 NOTCH2 PLXNB3 GPR179 IL27RA GP1BB

5.23e-0413537614GO:0004888
GeneOntologyBiologicalProcessskeletal system development

MKKS FAT4 FBN2 MEGF8 P2RX7 ADAMTS7 DLL3 PKD1 LRP5 DLK1 TWSG1 PDGFC ITGB6 ITGB8 NOTCH2

5.84e-096157615GO:0001501
GeneOntologyBiologicalProcessregulation of axon extension involved in axon guidance

PLXNA3 MEGF8 SLIT1 PLXNA4

3.91e-0717764GO:0048841
GeneOntologyBiologicalProcessaxon extension involved in axon guidance

PLXNA3 MEGF8 SLIT1 PLXNA4

1.18e-0622764GO:0048846
GeneOntologyBiologicalProcessneuron projection extension involved in neuron projection guidance

PLXNA3 MEGF8 SLIT1 PLXNA4

1.18e-0622764GO:1902284
GeneOntologyBiologicalProcessanatomical structure formation involved in morphogenesis

PLXNA3 FBN2 KDM4C DLL3 KIAA0319L PKD1 GRN PROK1 CLDN5 TWSG1 PLCD1 ITGB2 ITGB3 ITGB6 ITGB8 MEGF11 PLXNA1 NOTCH2 NOTCH4

1.24e-0614837619GO:0048646
GeneOntologyBiologicalProcesstube development

MKKS FAT4 MEGF8 PKD1 PLXNA4 LRP5 GRN PROK1 CLDN5 PLCD1 LOXL3 PDGFC ITGB2 ITGB3 ITGB6 ITGB8 NOTCH2 NOTCH4

2.44e-0614027618GO:0035295
GeneOntologyBiologicalProcesspositive regulation of axonogenesis

PLXNA3 MEGF8 GOLGA8H PLXNA4 PLXNA1 PLXNB3

3.98e-06114766GO:0050772
GeneOntologyBiologicalProcessregulation of axonogenesis

PLXNA3 MEGF8 GOLGA8H SLIT1 PLXNA4 PLXNA1 PLXNB3

6.90e-06192767GO:0050770
GeneOntologyBiologicalProcesscell-cell adhesion

FAT4 PKD1 LRP5 ASTN1 CLDN5 TWSG1 LOXL3 ITGB2 ITGB3 ITGB6 ITGB8 MEGF11 PLXNB3 NOTCH4 PEAR1

7.51e-0610777615GO:0098609
GeneOntologyBiologicalProcessregulation of anatomical structure morphogenesis

PLXNA3 MEGF8 GOLGA8H SLIT1 PLXNA4 GRN PROK1 CLDN5 ITGB2 ITGB3 ITGB8 PLXNA1 PLXNB3 NOTCH4 PINK1

8.67e-0610907615GO:0022603
GeneOntologyBiologicalProcessolfactory nerve formation

PLXNA3 PLXNA1

1.34e-052762GO:0021628
GeneOntologyBiologicalProcesspositive regulation of cell development

PLXNA3 MEGF8 GOLGA8H DLL3 PLXNA4 CLDN5 DLK1 ITGB3 PLXNA1 NOTCH2 PLXNB3

1.47e-056147611GO:0010720
GeneOntologyBiologicalProcesspositive regulation of cell differentiation

PLXNA3 NELL1 FBN2 MEGF8 GOLGA8H DLL3 PLXNA4 LRP5 CLDN5 DLK1 ITGB3 PLXNA1 NOTCH2 PLXNB3 NOTCH4

1.49e-0511417615GO:0045597
GeneOntologyBiologicalProcessplacenta blood vessel development

PKD1 PLCD1 ITGB8 NOTCH2

2.07e-0544764GO:0060674
GeneOntologyBiologicalProcessnegative chemotaxis

PLXNA3 SLIT1 PLXNA4 ITGB3

3.73e-0551764GO:0050919
GeneOntologyBiologicalProcessolfactory nerve morphogenesis

PLXNA3 PLXNA1

4.01e-053762GO:0021627
GeneOntologyBiologicalProcesssemaphorin-plexin signaling pathway

PLXNA3 PLXNA4 PLXNA1 PLXNB3

4.03e-0552764GO:0071526
GeneOntologyBiologicalProcessregulation of cell development

PLXNA3 MEGF8 GOLGA8H SLIT1 DLL3 PLXNA4 GRN CLDN5 DLK1 LOXL3 ITGB3 PLXNA1 NOTCH2 PLXNB3

4.08e-0510957614GO:0060284
GeneOntologyBiologicalProcesspositive regulation of neurogenesis

PLXNA3 MEGF8 GOLGA8H DLL3 PLXNA4 PLXNA1 NOTCH2 PLXNB3

4.75e-05354768GO:0050769
GeneOntologyBiologicalProcessanimal organ morphogenesis

MKKS FAT4 FBN2 MEGF8 P2RX7 SLIT1 PKD1 LRP5 CLDN5 TWSG1 PDGFC ITGB6 MEGF11 PLXNA1 NOTCH2

5.13e-0512697615GO:0009887
GeneOntologyBiologicalProcessbone development

FAT4 MEGF8 ADAMTS7 LRP5 PDGFC ITGB6 NOTCH2

5.35e-05264767GO:0060348
GeneOntologyBiologicalProcesstube morphogenesis

MKKS FAT4 MEGF8 PKD1 LRP5 GRN PROK1 CLDN5 PLCD1 ITGB2 ITGB3 ITGB8 NOTCH2 NOTCH4

5.47e-0511257614GO:0035239
GeneOntologyBiologicalProcessembryo development

MKKS FBN2 MEGF8 KDM4C DLL3 PKD1 PLXNA4 LRP5 GRN DLK1 TWSG1 PLCD1 LOXL3 LRP1B GRSF1 NOTCH2

5.67e-0514377616GO:0009790
GeneOntologyBiologicalProcesscellular response to growth factor stimulus

FAT4 FBN2 MEGF8 ADAMTS7 KCP CLDN5 TWSG1 ACAP2 ITGB3 ITGB6 ITGB8 NOTCH2

6.07e-058507612GO:0071363
GeneOntologyBiologicalProcessnegative regulation of cell adhesion

PLXNA3 SPACA7 PLXNA4 TWSG1 LOXL3 PLXNA1 PLXNB3 NOTCH4

7.11e-05375768GO:0007162
GeneOntologyBiologicalProcessLangerhans cell differentiation

ITGB6 ITGB8

8.00e-054762GO:0061520
GeneOntologyBiologicalProcessresponse to growth factor

FAT4 FBN2 MEGF8 ADAMTS7 KCP CLDN5 TWSG1 ACAP2 ITGB3 ITGB6 ITGB8 NOTCH2

8.73e-058837612GO:0070848
GeneOntologyBiologicalProcessmorphogenesis of an epithelium

MKKS FAT4 MEGF8 PKD1 LRP5 ITGB3 GRSF1 PLXNA1 NOTCH2 NOTCH4

8.85e-056197610GO:0002009
GeneOntologyBiologicalProcesstissue morphogenesis

MKKS FAT4 MEGF8 PKD1 LRP5 TWSG1 ITGB3 GRSF1 PLXNA1 NOTCH2 NOTCH4

9.07e-057507611GO:0048729
GeneOntologyBiologicalProcessintegrin-mediated signaling pathway

LOXL3 ITGB2 ITGB3 ITGB6 ITGB8

9.51e-05124765GO:0007229
GeneOntologyBiologicalProcesscell morphogenesis

PLXNA3 DIP2A MEGF8 P2RX7 GOLGA8H SLIT1 PLXNA4 ITGB2 ITGB3 ITGB6 PLXNA1 NOTCH2 PLXNB3 NOTCH4

1.03e-0411947614GO:0000902
GeneOntologyBiologicalProcessbone remodeling

P2RX7 LRP5 DLK1 ITGB3 NOTCH2

1.06e-04127765GO:0046849
GeneOntologyBiologicalProcessregulation of neurogenesis

PLXNA3 MEGF8 GOLGA8H SLIT1 DLL3 PLXNA4 PLXNA1 NOTCH2 PLXNB3

1.13e-04515769GO:0050767
GeneOntologyBiologicalProcessregulation of cell adhesion

PLXNA3 SPACA7 COL26A1 PKD1 PLXNA4 TWSG1 LOXL3 ITGB2 ITGB3 PLXNA1 PLXNB3 NOTCH4

1.38e-049277612GO:0030155
GeneOntologyBiologicalProcessblood vessel development

MEGF8 PKD1 LRP5 GRN PROK1 CLDN5 PLCD1 ITGB2 ITGB3 ITGB8 NOTCH2 NOTCH4

1.41e-049297612GO:0001568
GeneOntologyBiologicalProcessmyeloid dendritic cell differentiation

ITGB6 ITGB8 NOTCH2

1.47e-0428763GO:0043011
GeneOntologyBiologicalProcesscalcium ion transmembrane import into cytosol

P2RX7 PLCD1 ITGB3 TRPV5 GP1BB CEMIP

1.50e-04217766GO:0097553
GeneOntologyBiologicalProcesspositive regulation of nervous system development

PLXNA3 MEGF8 GOLGA8H DLL3 PLXNA4 PLXNA1 NOTCH2 PLXNB3

1.51e-04418768GO:0051962
GeneOntologyBiologicalProcessblood vessel morphogenesis

MEGF8 LRP5 GRN PROK1 CLDN5 PLCD1 ITGB2 ITGB3 ITGB8 NOTCH2 NOTCH4

1.92e-048177611GO:0048514
GeneOntologyBiologicalProcessestablishment of blood-retinal barrier

LRP5 CLDN5

1.99e-046762GO:1990963
GeneOntologyBiologicalProcesstrigeminal nerve morphogenesis

PLXNA3 PLXNA4

1.99e-046762GO:0021636
GeneOntologyBiologicalProcesstrigeminal nerve structural organization

PLXNA3 PLXNA4

1.99e-046762GO:0021637
GeneOntologyBiologicalProcessrelease of sequestered calcium ion into cytosol

P2RX7 PLCD1 ITGB3 GP1BB CEMIP

2.05e-04146765GO:0051209
GeneOntologyBiologicalProcessvasculature development

MEGF8 PKD1 LRP5 GRN PROK1 CLDN5 PLCD1 ITGB2 ITGB3 ITGB8 NOTCH2 NOTCH4

2.08e-049697612GO:0001944
GeneOntologyBiologicalProcessnegative regulation of sequestering of calcium ion

P2RX7 PLCD1 ITGB3 GP1BB CEMIP

2.11e-04147765GO:0051283
GeneOntologyBiologicalProcesscirculatory system development

MKKS FAT4 MEGF8 PKD1 PLXNA4 LRP5 GRN PROK1 CLDN5 PLCD1 ITGB2 ITGB3 ITGB8 NOTCH2 NOTCH4

2.13e-0414427615GO:0072359
GeneOntologyBiologicalProcesscranial nerve morphogenesis

PLXNA3 PLXNA4 PLXNA1

2.21e-0432763GO:0021602
GeneOntologyBiologicalProcessregulation of sequestering of calcium ion

P2RX7 PLCD1 ITGB3 GP1BB CEMIP

2.25e-04149765GO:0051282
GeneOntologyBiologicalProcesstransforming growth factor beta receptor superfamily signaling pathway

FBN2 MEGF8 KCP CLDN5 TWSG1 ITGB6 ITGB8 NOTCH2

2.30e-04445768GO:0141091
GeneOntologyBiologicalProcesssequestering of calcium ion

P2RX7 PLCD1 ITGB3 GP1BB CEMIP

2.54e-04153765GO:0051208
GeneOntologyBiologicalProcessepithelium development

MKKS FAT4 MEGF8 KRT40 DLL3 PKD1 PLXNA4 LRP5 CLDN5 LOXL3 ITGB3 GRSF1 PLXNA1 NOTCH2 NOTCH4

2.61e-0414697615GO:0060429
GeneOntologyBiologicalProcessregulation of osteoblast proliferation

NELL1 LRP5 ITGB3

2.65e-0434763GO:0033688
GeneOntologyBiologicalProcessconnective tissue development

MKKS ADAMTS7 PKD1 LRP5 TWSG1 ITGB3 ITGB8

2.70e-04343767GO:0061448
GeneOntologyBiologicalProcessgonadotrophin-releasing hormone neuronal migration to the hypothalamus

PLXNA3 PLXNA1

2.78e-047762GO:0021828
GeneOntologyBiologicalProcesshypothalamic tangential migration using cell-axon interactions

PLXNA3 PLXNA1

2.78e-047762GO:0021856
GeneOntologyBiologicalProcessbranchiomotor neuron axon guidance

PLXNA3 PLXNA4

2.78e-047762GO:0021785
GeneOntologyBiologicalProcessmotor neuron axon guidance

PLXNA3 SLIT1 PLXNA4

2.89e-0435763GO:0008045
GeneOntologyBiologicalProcessregulation of cell shape

PLXNA3 PLXNA4 ITGB2 PLXNA1 PLXNB3

3.04e-04159765GO:0008360
GeneOntologyBiologicalProcessregulation of locomotion

MKKS PLXNA3 FBN2 MEGF8 SLIT1 PLXNA4 GRN CLDN5 PDGFC ITGB3 PLXNA1 PLXNB3 IL27RA CEMIP

3.10e-0413277614GO:0040012
GeneOntologyBiologicalProcesscell adhesion mediated by integrin

ITGB2 ITGB3 ITGB6 ITGB8

3.57e-0491764GO:0033627
GeneOntologyBiologicalProcessolfactory nerve development

PLXNA3 PLXNA1

3.70e-048762GO:0021553
GeneOntologyBiologicalProcessmaintenance of location in cell

P2RX7 PLCD1 ITGB3 PINK1 GP1BB CEMIP

3.88e-04259766GO:0051651
GeneOntologyBiologicalProcesscell surface receptor protein serine/threonine kinase signaling pathway

FBN2 MEGF8 KCP CLDN5 TWSG1 ITGB6 ITGB8 NOTCH2

3.93e-04482768GO:0007178
GeneOntologyBiologicalProcesspositive regulation of cellular component organization

PLXNA3 MEGF8 P2RX7 GOLGA8H PLXNA4 ANAPC11 LRP5 SIVA1 GRN CLDN5 PLXNA1 PLXNB3 SLX1A PINK1

4.16e-0413667614GO:0051130
GeneOntologyBiologicalProcessmaintenance of synapse structure

PLXNA4 GRN ITGB3

4.31e-0440763GO:0099558
GeneOntologyBiologicalProcessactivation of protein kinase activity

PDGFC ITGB3 NOTCH2 PINK1

4.55e-0497764GO:0032147
GeneOntologyBiologicalProcesspositive regulation of cell projection organization

PLXNA3 MEGF8 P2RX7 GOLGA8H PLXNA4 GRN PLXNA1 PLXNB3

4.63e-04494768GO:0031346
GeneOntologyBiologicalProcessosteoblast proliferation

NELL1 LRP5 ITGB3

4.63e-0441763GO:0033687
GeneOntologyBiologicalProcesshypothalamus cell migration

PLXNA3 PLXNA1

4.74e-049762GO:0021855
GeneOntologyBiologicalProcesshypothalamus gonadotrophin-releasing hormone neuron differentiation

PLXNA3 PLXNA1

4.74e-049762GO:0021886
GeneOntologyBiologicalProcesshypothalamus gonadotrophin-releasing hormone neuron development

PLXNA3 PLXNA1

4.74e-049762GO:0021888
GeneOntologyBiologicalProcessregulation of nervous system development

PLXNA3 MEGF8 GOLGA8H SLIT1 DLL3 PLXNA4 PLXNA1 NOTCH2 PLXNB3

4.75e-04625769GO:0051960
GeneOntologyBiologicalProcesscell-matrix adhesion

NID2 PKD1 ITGB2 ITGB3 ITGB6 ITGB8

4.83e-04270766GO:0007160
GeneOntologyBiologicalProcesspositive regulation of BMP signaling pathway

KCP TWSG1 NOTCH2

4.98e-0442763GO:0030513
GeneOntologyBiologicalProcessembryonic heart tube development

MKKS MEGF8 PLXNA4 NOTCH2

5.71e-04103764GO:0035050
GeneOntologyBiologicalProcesspositive regulation of osteoclast differentiation

DLK1 ITGB3 NOTCH2

5.71e-0444763GO:0045672
GeneOntologyBiologicalProcessaxon development

PLXNA3 MEGF8 GOLGA8H SLIT1 PLXNA4 GRN PLXNA1 NOTCH2 PLXNB3

5.76e-04642769GO:0061564
GeneOntologyBiologicalProcessfacial nerve structural organization

PLXNA3 PLXNA4

5.92e-0410762GO:0021612
GeneOntologyBiologicalProcesshard palate development

ITGB6 ITGB8

5.92e-0410762GO:0060022
GeneOntologyBiologicalProcessregulation of axon extension

PLXNA3 MEGF8 SLIT1 PLXNA4

5.92e-04104764GO:0030516
GeneOntologyBiologicalProcessroof of mouth development

CLDN5 LOXL3 ITGB6 ITGB8

5.92e-04104764GO:0060021
GeneOntologyBiologicalProcesscalcium ion transmembrane transport

P2RX7 PKD1 PLCD1 ITGB3 TRPV5 GP1BB CEMIP

6.02e-04392767GO:0070588
GeneOntologyBiologicalProcessmaintenance of location

FBN2 P2RX7 PLCD1 ITGB3 PINK1 GP1BB CEMIP

6.39e-04396767GO:0051235
GeneOntologyBiologicalProcessmyeloid dendritic cell activation

ITGB6 ITGB8 NOTCH2

6.51e-0446763GO:0001773
GeneOntologyBiologicalProcessneuron projection guidance

PLXNA3 MEGF8 SLIT1 PLXNA4 PLXNA1 NOTCH2

6.54e-04286766GO:0097485
GeneOntologyBiologicalProcessregulation of osteoblast differentiation

NELL1 FBN2 LRP5 DLK1 TWSG1

7.18e-04192765GO:0045667
GeneOntologyBiologicalProcessinositol trisphosphate biosynthetic process

SCP2 PLCD1

7.21e-0411762GO:0032959
GeneOntologyBiologicalProcessnegative regulation of axon extension involved in axon guidance

PLXNA3 SLIT1

7.21e-0411762GO:0048843
GeneOntologyBiologicalProcesscranial nerve formation

PLXNA3 PLXNA1

7.21e-0411762GO:0021603
GeneOntologyBiologicalProcessnegative regulation of Notch signaling pathway

DLL3 DLK1 NOTCH4

7.38e-0448763GO:0045746
GeneOntologyBiologicalProcesscell-substrate adhesion

NID2 COL26A1 PKD1 ITGB2 ITGB3 ITGB6 ITGB8

7.83e-04410767GO:0031589
GeneOntologyBiologicalProcesspositive regulation of bone mineralization

NELL1 FBN2 P2RX7

7.84e-0449763GO:0030501
GeneOntologyBiologicalProcessplacenta development

FBN2 PKD1 PLCD1 ITGB8 NOTCH2

8.06e-04197765GO:0001890
GeneOntologyBiologicalProcesscell fate determination

DLL3 NOTCH2 NOTCH4

8.32e-0450763GO:0001709
GeneOntologyBiologicalProcessfacial nerve morphogenesis

PLXNA3 PLXNA4

8.63e-0412762GO:0021610
GeneOntologyBiologicalProcessfacial nerve development

PLXNA3 PLXNA4

8.63e-0412762GO:0021561
GeneOntologyBiologicalProcesscell projection morphogenesis

PLXNA3 DIP2A MEGF8 GOLGA8H SLIT1 PLXNA4 ITGB3 PLXNA1 NOTCH2 PLXNB3

8.77e-048267610GO:0048858
GeneOntologyBiologicalProcessregulation of angiogenesis

GRN PROK1 CLDN5 ITGB2 ITGB3 ITGB8 NOTCH4

9.02e-04420767GO:0045765
GeneOntologyBiologicalProcessepithelial tube morphogenesis

MKKS FAT4 MEGF8 PKD1 LRP5 NOTCH2 NOTCH4

9.14e-04421767GO:0060562
GeneOntologyBiologicalProcessbiomineral tissue development

NELL1 FBN2 P2RX7 DLK1 ITGB6

9.22e-04203765GO:0031214
GeneOntologyCellularComponentreceptor complex

PLXNA3 GPR62 PLXNA4 LRP5 LRP1B ITGB2 ITGB3 ITGB6 ITGB8 PLXNA1 NOTCH2 PLXNB3 IL27RA GP1BB

2.36e-085817714GO:0043235
GeneOntologyCellularComponentsemaphorin receptor complex

PLXNA3 PLXNA4 PLXNA1 PLXNB3

1.19e-0713774GO:0002116
GeneOntologyCellularComponentcell surface

NID2 DIP2A P2RX7 ADAMTS7 PKD1 ASTN1 DLK1 GPC5 PDGFC ITGB2 ITGB3 ITGB6 ITGB8 NOTCH2 PLXNB3 NOTCH4 IL27RA

4.54e-0711117717GO:0009986
GeneOntologyCellularComponentintegrin complex

ITGB2 ITGB3 ITGB6 ITGB8

5.66e-0632774GO:0008305
GeneOntologyCellularComponentextracellular matrix

NID2 FCGBP FBN2 COL26A1 MEGF6 ADAMTS7 MUC5B GPC5 LOXL3 SSPOP FBN3

2.72e-056567711GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

NID2 FCGBP FBN2 COL26A1 MEGF6 ADAMTS7 MUC5B GPC5 LOXL3 SSPOP FBN3

2.80e-056587711GO:0030312
GeneOntologyCellularComponentprotein complex involved in cell adhesion

ITGB2 ITGB3 ITGB6 ITGB8

6.64e-0559774GO:0098636
GeneOntologyCellularComponentcerebellar climbing fiber to Purkinje cell synapse

PLXNA4 GRN

7.21e-0411772GO:0150053
GeneOntologyCellularComponentmicrofibril

FBN2 FBN3

1.02e-0313772GO:0001527
GeneOntologyCellularComponentGolgi membrane

LITAF GOLGA8H KIAA0319L PKD1 SERINC3 PDGFC GALNT4 NOTCH2 NOTCH4

1.31e-03721779GO:0000139
GeneOntologyCellularComponentside of membrane

P2RX7 LITAF ASTN1 DLK1 GPC5 ITGB2 ITGB3 ITGB6 ALG1 IL27RA

1.36e-038757710GO:0098552
MousePhenoabnormal vertebrae development

NELL1 FAT4 DLL3 PKD1 TWSG1 LOXL3 PDGFC

1.18e-0859677MP:0005225
MousePhenoabnormal skeleton physiology

NELL1 NID2 FAT4 FBN2 MEGF8 P2RX7 DLL3 PKD1 LRP5 TWSG1 ITGB2 ITGB3 NOTCH2 IL27RA

1.37e-066326714MP:0001533
MousePhenoabnormal macrophage cell number

P2RX7 LITAF GOLGA8H LRP5 ITGB2 ITGB3 TRPV5 NOTCH2 CEMIP

6.66e-06278679MP:0020202
MousePhenoabnormal skeleton development

NELL1 FAT4 FBN2 P2RX7 DLL3 PKD1 TWSG1 LOXL3 PDGFC NOTCH2 CEMIP

8.07e-064476711MP:0002113
MousePhenoabnormal trabecular bone morphology

DLL3 PKD1 LRP5 TWSG1 ITGB2 ITGB3 TRPV5 PLXNA1 NOTCH2

9.11e-06289679MP:0000130
MousePhenoabnormal mononuclear phagocyte morphology

P2RX7 LITAF GOLGA8H LRP5 GRN TWSG1 PDGFC ITGB2 ITGB3 ITGB6 TRPV5 NOTCH2 CEMIP

2.49e-057056713MP:0008248
MousePhenoabnormal osteoclast cell number

P2RX7 LRP5 ITGB3 TRPV5 NOTCH2 CEMIP

3.31e-05128676MP:0004983
MousePhenodecreased diameter of femur

P2RX7 LRP5 NOTCH2

5.64e-0516673MP:0008152
MousePhenoabnormal trabecular bone mass

PKD1 LRP5 ITGB2 PLXNA1

6.19e-0545674MP:0010871
MousePhenoabnormal macrophage morphology

P2RX7 LITAF GOLGA8H LRP5 GRN ITGB2 ITGB3 TRPV5 NOTCH2 CEMIP

6.58e-054636710MP:0002446
MousePhenoabnormal appendicular skeleton morphology

FAT4 FBN2 MEGF8 P2RX7 DLL3 PKD1 LRP5 TWSG1 ITGB2 SSPOP TRPV5 PLXNA1 NOTCH2 CEMIP

7.17e-058966714MP:0009250
MousePhenodecreased bone mineral density of femur

LRP5 TWSG1 ITGB2 NOTCH2

7.36e-0547674MP:0020010
MousePhenothin neurocranium

NELL1 LRP5 TWSG1

8.16e-0518673MP:0030279
MousePhenoabnormal bone ossification

NELL1 FAT4 MEGF8 DLL3 PKD1 LRP5 TWSG1 ITGB2 NOTCH2

1.05e-04395679MP:0008271
MousePhenodecreased trabecular bone mass

PKD1 LRP5 ITGB2

1.13e-0420673MP:0010873
MousePhenoabnormal professional antigen presenting cell morphology

P2RX7 LITAF GOLGA8H LRP5 GRN DLK1 ITGB2 ITGB3 ITGB6 TRPV5 NOTCH2 CEMIP

1.51e-047266712MP:0008195
MousePhenoabnormal compact bone morphology

DLL3 PKD1 LRP5 ITGB3 TRPV5 NOTCH2

1.71e-04172676MP:0003797
MousePhenodecreased diameter of long bones

P2RX7 LRP5 NOTCH2

1.74e-0423673MP:0008150
MousePhenoabnormal bone structure

NELL1 FBN2 MEGF6 P2RX7 DLL3 KIAA0319L PKD1 LRP5 SERINC3 TWSG1 ITGB2 ITGB3 TRPV5 PLXNA1 NOTCH2 PINK1 CEMIP

2.02e-0413796717MP:0003795
MousePhenoabnormal vertebral arch development

PKD1 TWSG1 PDGFC

2.24e-0425673MP:0005226
MousePhenoabnormal bone mineral density of femur

LRP5 TWSG1 ITGB2 NOTCH2

2.32e-0463674MP:0020009
MousePhenoabnormal osteoclast morphology

P2RX7 LRP5 ITGB3 TRPV5 NOTCH2 CEMIP

2.39e-04183676MP:0004982
MousePhenoabnormal kidney cell proliferation

FAT4 PKD1 NOTCH2

2.53e-0426673MP:0011439
MousePhenoabnormal vertebrae morphology

NELL1 FAT4 FBN2 DLL3 PKD1 LRP5 TWSG1 LOXL3 PDGFC NOTCH2

2.54e-045466710MP:0000137
MousePhenoabnormal myeloid leukocyte morphology

P2RX7 LITAF GOLGA8H PKD1 LRP5 GRN TWSG1 PLCD1 PDGFC ITGB2 ITGB3 ITGB6 TRPV5 ALG1 NOTCH2 CEMIP

3.10e-0412926716MP:0008250
MousePhenoabnormal phagocyte morphology

P2RX7 LITAF GOLGA8H PKD1 LRP5 GRN TWSG1 PDGFC ITGB2 ITGB3 ITGB6 TRPV5 NOTCH2 CEMIP

3.21e-0410336714MP:0008251
MousePhenodecreased diameter of tibia

P2RX7 LRP5

3.35e-046672MP:0008156
MousePhenodecreased bone mineral density

NELL1 KIAA0319L PKD1 LRP5 SERINC3 TWSG1 ITGB2 NOTCH2 PINK1

4.22e-04476679MP:0000063
MousePhenothin parietal bone

NELL1 LRP5

4.68e-047672MP:0030281
MousePhenoincreased osteoclast cell number

P2RX7 ITGB3 TRPV5 NOTCH2

5.01e-0477674MP:0004984
MousePhenoabnormal femur morphology

FBN2 P2RX7 LRP5 TWSG1 NOTCH2 CEMIP

5.50e-04214676MP:0000559
MousePhenoabnormal hindlimb stylopod morphology

FBN2 P2RX7 LRP5 TWSG1 NOTCH2 CEMIP

5.64e-04215676MP:0003856
MousePhenodecreased bone ossification

NELL1 LRP5 ITGB2

7.28e-0437673MP:0020040
MousePhenodecreased kidney cell proliferation

FAT4 NOTCH2

7.97e-049672MP:0011441
DomainEGF_2

NELL1 NID2 FAT4 FBN2 MEGF6 MEGF8 ATRNL1 SLIT1 DLL3 LRP5 ASTN1 DLK1 LRP1B ITGB2 SSPOP ITGB3 ITGB6 ITGB8 MEGF11 FBN3 NOTCH2 NOTCH4 PEAR1

7.35e-252657523PS01186
DomainEGF_1

NELL1 FAT4 FBN2 MEGF6 MEGF8 ATRNL1 SLIT1 DLL3 LRP5 ASTN1 DLK1 LRP1B ITGB2 SSPOP ITGB3 ITGB6 ITGB8 MEGF11 FBN3 NOTCH2 NOTCH4 PEAR1

1.03e-232557522PS00022
DomainEGF-like_CS

NELL1 NID2 FAT4 FBN2 MEGF6 MEGF8 ATRNL1 SLIT1 DLL3 LRP5 ASTN1 DLK1 LRP1B ITGB2 ITGB3 ITGB6 ITGB8 MEGF11 FBN3 NOTCH2 NOTCH4 PEAR1

1.72e-232617522IPR013032
DomainEGF

NELL1 NID2 FAT4 FCGBP FBN2 MEGF6 MEGF8 ATRNL1 SLIT1 DLL3 LRP5 ASTN1 DLK1 LRP1B ITGB8 MEGF11 FBN3 NOTCH2 GPR179 NOTCH4 PEAR1

5.81e-232357521SM00181
DomainEGF_3

NELL1 NID2 FAT4 FBN2 MEGF6 MEGF8 ATRNL1 SLIT1 DLL3 LRP5 ASTN1 DLK1 LRP1B SSPOP MEGF11 FBN3 NOTCH2 NOTCH4 PEAR1

5.80e-202357519PS50026
DomainEGF-like_dom

NELL1 NID2 FAT4 FCGBP FBN2 MEGF6 MEGF8 ATRNL1 SLIT1 DLL3 LRP5 ASTN1 DLK1 LRP1B MEGF11 FBN3 NOTCH2 NOTCH4 PEAR1

1.75e-192497519IPR000742
DomainEGF-like_Ca-bd_dom

NELL1 NID2 FAT4 FBN2 MEGF6 MEGF8 SLIT1 DLL3 LRP5 DLK1 LRP1B FBN3 NOTCH2 NOTCH4

6.07e-171247514IPR001881
DomainEGF_extracell

NELL1 MEGF6 ATRNL1 DLL3 DLK1 LRP1B ITGB2 ITGB3 ITGB6 ITGB8 MEGF11

5.97e-16607511IPR013111
DomainEGF_2

NELL1 MEGF6 ATRNL1 DLL3 DLK1 LRP1B ITGB2 ITGB3 ITGB6 ITGB8 MEGF11

5.97e-16607511PF07974
DomainhEGF

FAT4 FBN2 MEGF6 SLIT1 DLL3 MEGF11 FBN3 NOTCH2 NOTCH4

1.07e-1528759PF12661
DomainPSI

PLXNA3 MEGF8 ATRNL1 PLXNA4 ITGB2 ITGB3 ITGB6 ITGB8 PLXNA1 PLXNB3

1.30e-15447510IPR016201
DomainEGF_CA

NELL1 NID2 FAT4 FBN2 MEGF6 MEGF8 SLIT1 DLL3 DLK1 LRP1B FBN3 NOTCH2 NOTCH4

1.84e-151227513SM00179
DomainPSI

PLXNA3 MEGF8 ATRNL1 PLXNA4 ITGB2 ITGB3 ITGB6 ITGB8 PLXNA1 PLXNB3

2.12e-15467510SM00423
DomainEGF_CA

NELL1 NID2 FAT4 FBN2 MEGF6 MEGF8 SLIT1 LRP5 LRP1B FBN3 NOTCH2 NOTCH4

4.91e-15997512PS01187
DomainEGF-type_Asp/Asn_hydroxyl_site

NELL1 NID2 FAT4 FBN2 MEGF6 MEGF8 SLIT1 DLK1 LRP1B FBN3 NOTCH2 NOTCH4

1.14e-141067512IPR000152
DomainGrowth_fac_rcpt_

NELL1 NID2 FAT4 FBN2 MEGF6 MEGF8 SLIT1 DLL3 LRP1B FBN3 NOTCH2 GPR179 NOTCH4

4.70e-141567513IPR009030
DomainEGF_Ca-bd_CS

NELL1 NID2 FAT4 FBN2 MEGF6 MEGF8 SLIT1 LRP1B FBN3 NOTCH2 NOTCH4

1.54e-13977511IPR018097
DomainASX_HYDROXYL

NELL1 NID2 FAT4 FBN2 MEGF6 MEGF8 DLK1 LRP1B FBN3 NOTCH2 NOTCH4

2.17e-131007511PS00010
DomainEGF_CA

NELL1 NID2 FAT4 FBN2 MEGF6 MEGF8 LRP1B FBN3 NOTCH2 NOTCH4

1.62e-12867510PF07645
DomainEGF

NID2 MEGF6 SLIT1 DLL3 LRP5 DLK1 LRP1B ITGB3 FBN3 NOTCH2 NOTCH4

2.87e-121267511PF00008
DomainIntegin_beta_N

MEGF8 ITGB2 ITGB3 ITGB6 ITGB8

1.13e-109755IPR033760
DomainPSI_integrin

MEGF8 ITGB2 ITGB3 ITGB6 ITGB8

1.13e-109755PF17205
DomainPSI

PLXNA3 MEGF8 ATRNL1 PLXNA4 PLXNA1 PLXNB3

2.85e-0932756PF01437
DomainPlexin_repeat

PLXNA3 MEGF8 ATRNL1 PLXNA4 PLXNA1 PLXNB3

2.85e-0932756IPR002165
DomainEMI

COL26A1 MEGF6 SSPOP MEGF11 PEAR1

5.43e-0917755PS51041
DomainVWC_out

NELL1 FCGBP KCP MUC5B SSPOP

1.01e-0819755SM00215
DomainIntegrin_beta

ITGB2 ITGB3 ITGB6 ITGB8

1.66e-088754PF00362
DomainINB

ITGB2 ITGB3 ITGB6 ITGB8

1.66e-088754SM00187
DomainIntegrin_bsu_VWA

ITGB2 ITGB3 ITGB6 ITGB8

1.66e-088754IPR002369
DomainPlexin_cytopl

PLXNA3 PLXNA4 PLXNA1 PLXNB3

2.98e-089754PF08337
DomainPlexin_cytoplasmic_RasGAP_dom

PLXNA3 PLXNA4 PLXNA1 PLXNB3

2.98e-089754IPR013548
DomainIntegrin_bsu

ITGB2 ITGB3 ITGB6 ITGB8

2.98e-089754IPR015812
DomainPlexin

PLXNA3 PLXNA4 PLXNA1 PLXNB3

2.98e-089754IPR031148
DomainINTEGRIN_BETA

ITGB2 ITGB3 ITGB6 ITGB8

2.98e-089754PS00243
DomainUnchr_dom_Cys-rich

FCGBP KCP MUC5B SSPOP

1.67e-0713754IPR014853
DomainC8

FCGBP KCP MUC5B SSPOP

1.67e-0713754SM00832
DomainTIL_dom

FCGBP KCP MUC5B SSPOP

2.33e-0714754IPR002919
DomainEGF_Lam

MEGF6 MEGF8 ATRNL1 MEGF11 PEAR1

2.69e-0735755SM00180
DomainVWC

NELL1 FCGBP KCP MUC5B SSPOP

4.13e-0738755SM00214
DomainLaminin_EGF

MEGF6 MEGF8 ATRNL1 MEGF11 PEAR1

4.13e-0738755IPR002049
DomainVWD

FCGBP KCP MUC5B SSPOP

4.21e-0716754SM00216
DomainEMI_domain

COL26A1 MEGF6 MEGF11 PEAR1

4.21e-0716754IPR011489
DomainVWF_type-D

FCGBP KCP MUC5B SSPOP

4.21e-0716754IPR001846
DomainVWFD

FCGBP KCP MUC5B SSPOP

4.21e-0716754PS51233
DomainVWD

FCGBP KCP MUC5B SSPOP

4.21e-0716754PF00094
DomainVWF_dom

NELL1 FCGBP KCP MUC5B SSPOP

6.91e-0742755IPR001007
DomainIntegrin_bsu_cyt_dom

ITGB2 ITGB3 ITGB6

1.23e-066753IPR014836
DomainIntegrin_b_cyt

ITGB2 ITGB3 ITGB6

1.23e-066753SM01241
DomainIntegrin_b_cyt

ITGB2 ITGB3 ITGB6

1.23e-066753PF08725
DomainIntegrin_bsu_tail

ITGB2 ITGB3 ITGB6

2.15e-067753IPR012896
DomainIntegrin_B_tail

ITGB2 ITGB3 ITGB6

2.15e-067753SM01242
DomainIntegrin_B_tail

ITGB2 ITGB3 ITGB6

2.15e-067753PF07965
DomainIntegrin_dom

ITGB2 ITGB3 ITGB6 ITGB8

2.85e-0625754IPR032695
DomaincEGF

NID2 FBN2 LRP1B FBN3

3.35e-0626754IPR026823
DomaincEGF

NID2 FBN2 LRP1B FBN3

3.35e-0626754PF12662
DomainIPT

PLXNA3 PLXNA4 PLXNA1 PLXNB3

3.92e-0627754SM00429
DomainTIG

PLXNA3 PLXNA4 PLXNA1 PLXNB3

6.95e-0631754PF01833
DomainSema

PLXNA3 PLXNA4 PLXNA1 PLXNB3

6.95e-0631754SM00630
DomainSemap_dom

PLXNA3 PLXNA4 PLXNA1 PLXNB3

6.95e-0631754IPR001627
DomainSema

PLXNA3 PLXNA4 PLXNA1 PLXNB3

6.95e-0631754PF01403
DomainSEMA

PLXNA3 PLXNA4 PLXNA1 PLXNB3

6.95e-0631754PS51004
DomainIPT

PLXNA3 PLXNA4 PLXNA1 PLXNB3

7.92e-0632754IPR002909
DomainLaminin_EGF

MEGF6 MEGF8 MEGF11 PEAR1

1.14e-0535754PF00053
DomainVWFC_1

NELL1 KCP MUC5B SSPOP

1.28e-0536754PS01208
DomainEGF_3

NELL1 NID2 MEGF8

1.33e-0512753PF12947
DomainTIL

FCGBP MUC5B SSPOP

1.33e-0512753PF01826
DomainEGF_dom

NELL1 NID2 MEGF8

1.33e-0512753IPR024731
DomainC8

FCGBP MUC5B SSPOP

1.33e-0512753PF08742
DomainVWFC_2

NELL1 KCP MUC5B SSPOP

1.60e-0538754PS50184
DomainLdl_recept_b

NID2 LRP5 LRP1B

2.19e-0514753PF00058
DomainLDLRB

NID2 LRP5 LRP1B

2.19e-0514753PS51120
DomainLY

NID2 LRP5 LRP1B

2.73e-0515753SM00135
DomainLDLR_classB_rpt

NID2 LRP5 LRP1B

2.73e-0515753IPR000033
DomainLDLRA_1

PKD1 LRP5 LRP1B SSPOP

4.08e-0548754PS01209
DomainLDLRA_2

PKD1 LRP5 LRP1B SSPOP

4.43e-0549754PS50068
DomainFBN

FBN2 FBN3

4.76e-053752IPR011398
DomainCTCK_1

SLIT1 MUC5B SSPOP

4.86e-0518753PS01185
DomainNotch

NOTCH2 NOTCH4

9.50e-054752IPR008297
DomainNODP

NOTCH2 NOTCH4

9.50e-054752PF07684
DomainNotch_NODP_dom

NOTCH2 NOTCH4

9.50e-054752IPR011656
DomainNotch_NOD_dom

NOTCH2 NOTCH4

9.50e-054752IPR010660
DomainNOD

NOTCH2 NOTCH4

9.50e-054752PF06816
Domain-

ITGB3 ITGB6

9.50e-0547521.20.5.630
DomainNOD

NOTCH2 NOTCH4

9.50e-054752SM01338
DomainNODP

NOTCH2 NOTCH4

9.50e-054752SM01339
DomainCys_knot_C

SLIT1 MUC5B SSPOP

1.34e-0425753IPR006207
DomainCTCK_2

SLIT1 MUC5B SSPOP

1.34e-0425753PS01225
DomainLNR

NOTCH2 NOTCH4

1.58e-045752PS50258
DomainVWC

NELL1 KCP MUC5B

1.90e-0428753PF00093
Domain-

ITGB2 ITGB3 ITGB6 ITGB8

2.23e-04747543.40.50.410
DomainPKD/REJ-like

KIAA0319L PKD1

2.36e-046752IPR002859
DomainREJ

KIAA0319L PKD1

2.36e-046752PF02010
DomainWxxW_domain

MUC5B CEMIP

2.36e-046752IPR025155
DomainMucin2_WxxW

MUC5B CEMIP

2.36e-046752PF13330
DomainTB

FBN2 FBN3

3.30e-047752PF00683
DomainNotch_dom

NOTCH2 NOTCH4

3.30e-047752IPR000800
DomainNotch

NOTCH2 NOTCH4

3.30e-047752PF00066
DomainNL

NOTCH2 NOTCH4

3.30e-047752SM00004
DomainVWFA

ITGB2 ITGB3 ITGB6 ITGB8

3.31e-0482754PS50234
DomainVWA

ITGB2 ITGB3 ITGB6 ITGB8

3.63e-0484754SM00327
PathwayREACTOME_ELASTIC_FIBRE_FORMATION

FBN2 LOXL3 ITGB3 ITGB6 ITGB8 FBN3

4.25e-0844646M26969
PathwayREACTOME_MOLECULES_ASSOCIATED_WITH_ELASTIC_FIBRES

FBN2 ITGB3 ITGB6 ITGB8 FBN3

6.41e-0737645M27134
PathwayREACTOME_ELASTIC_FIBRE_FORMATION

FBN2 LOXL3 ITGB3 ITGB6 ITGB8

8.41e-0739645MM14601
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

NID2 FBN2 COL26A1 MEGF6 LOXL3 ITGB2 ITGB3 ITGB6 ITGB8

2.29e-06258649MM14572
PathwayREACTOME_DISEASES_OF_GLYCOSYLATION

ADAMTS7 MUC5B GPC5 SSPOP ALG1 NOTCH2 NOTCH4

3.66e-06143647M27275
PathwayPID_INTEGRIN_CS_PATHWAY

ITGB2 ITGB3 ITGB6 ITGB8

5.36e-0626644M47
PathwayWP_CANONICAL_AND_NONCANONICAL_NOTCH_SIGNALING

DLL3 DLK1 NOTCH2 NOTCH4

6.27e-0627644M39545
PathwayPID_NOTCH_PATHWAY

DLL3 DLK1 SSPOP NOTCH2 NOTCH4

6.82e-0659645M17
PathwayREACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION

PLXNA3 PLXNA4 PLXNA1

7.35e-069643MM15030
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

NID2 FBN2 COL26A1 LOXL3 ITGB2 ITGB3 ITGB6 ITGB8 FBN3

7.83e-06300649M610
PathwayWP_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_IN_COLORECTAL_CANCER

DLL3 PKD1 LRP5 CLDN5 DLK1 NOTCH2 NOTCH4

8.00e-06161647M39770
PathwayREACTOME_MOLECULES_ASSOCIATED_WITH_ELASTIC_FIBRES

FBN2 ITGB3 ITGB6 ITGB8

1.26e-0532644MM14854
PathwayREACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS

ADAMTS7 MUC5B SSPOP NOTCH2 NOTCH4

1.38e-0568645M27303
PathwayKEGG_MEDICUS_REFERENCE_NOTCH_SIGNALING_PATHWAY

DLL3 NOTCH2 NOTCH4

2.47e-0513643M47423
PathwayREACTOME_SEMA3A_PAK_DEPENDENT_AXON_REPULSION

PLXNA3 PLXNA4 PLXNA1

3.13e-0514643MM15029
PathwayREACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION

PLXNA3 PLXNA4 PLXNA1

3.13e-0514643M7578
PathwayREACTOME_CRMPS_IN_SEMA3A_SIGNALING

PLXNA3 PLXNA4 PLXNA1

3.91e-0515643MM15031
PathwayREACTOME_SEMA3A_PAK_DEPENDENT_AXON_REPULSION

PLXNA3 PLXNA4 PLXNA1

4.79e-0516643M16498
PathwayREACTOME_CRMPS_IN_SEMA3A_SIGNALING

PLXNA3 PLXNA4 PLXNA1

4.79e-0516643M8245
PathwayWP_MECHANOREGULATION_AND_PATHOLOGY_OF_YAPTAZ_VIA_HIPPO_AND_NONHIPPO_MECHANISMS

ITGB2 ITGB3 ITGB6 ITGB8

5.95e-0547644M39829
PathwayREACTOME_OTHER_SEMAPHORIN_INTERACTIONS

PLXNA4 PLXNA1 PLXNB3

8.21e-0519643M10959
PathwayREACTOME_SEMAPHORIN_INTERACTIONS

PLXNA3 PLXNA4 PLXNA1 PLXNB3

8.23e-0551644MM14967
PathwayREACTOME_DISEASES_OF_METABOLISM

ADAMTS7 MUC5B GPC5 SSPOP ALG1 NOTCH2 NOTCH4

1.33e-04250647M27554
PathwayKEGG_MEDICUS_REFERENCE_ITGA_B_RHOGAP_RHOA_SIGNALING_PATHWAY

ITGB3 ITGB6 ITGB8

1.48e-0423643M47537
PathwayKEGG_MEDICUS_REFERENCE_ITGA_B_RHOGEF_RHOA_SIGNALING_PATHWAY

ITGB3 ITGB6 ITGB8

1.48e-0423643M47720
PathwayREACTOME_SEMAPHORIN_INTERACTIONS

PLXNA3 PLXNA4 PLXNA1 PLXNB3

2.00e-0464644M7923
PathwayREACTOME_DEFECTIVE_LFNG_CAUSES_SCDO3

NOTCH2 NOTCH4

2.01e-045642M27411
PathwayKEGG_MEDICUS_REFERENCE_ITGA_B_FAK_CDC42_SIGNALING_PATHWAY

ITGB3 ITGB6 ITGB8

2.15e-0426643M47719
PathwayKEGG_MEDICUS_REFERENCE_ITGA_B_RHOG_RAC_SIGNALING_PATHWAY

ITGB3 ITGB6 ITGB8

2.70e-0428643M47655
PathwayREACTOME_PRE_NOTCH_PROCESSING_IN_THE_ENDOPLASMIC_RETICULUM

NOTCH2 NOTCH4

3.01e-046642M27068
PathwayKEGG_MEDICUS_REFERENCE_ITGA_B_TALIN_VINCULIN_SIGNALING_PATHWAY

ITGB3 ITGB6 ITGB8

3.32e-0430643M47724
PathwayKEGG_MEDICUS_REFERENCE_ITGA_B_FAK_RAC_SIGNALING_PATHWAY

ITGB3 ITGB6 ITGB8

3.32e-0430643M47718
PathwayREACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS

ITGB2 ITGB3 ITGB6 ITGB8

3.88e-0476644MM14867
PathwayKEGG_ECM_RECEPTOR_INTERACTION

ITGB3 ITGB6 ITGB8 GP1BB

5.68e-0484644M7098
PathwayREACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS

ITGB2 ITGB3 ITGB6 ITGB8

5.94e-0485644M16441
PathwayREACTOME_TGF_BETA_RECEPTOR_SIGNALING_ACTIVATES_SMADS

ITGB3 ITGB6 ITGB8

6.72e-0438643MM14874
PathwayKEGG_MEDICUS_REFERENCE_NOTCH_PROTEOLYTIC_ACTIVATION

NOTCH2 NOTCH4

1.09e-0311642M47865
PathwayWP_NOTCH_SIGNALING_WP268

DLL3 NOTCH2 NOTCH4

1.11e-0345643M39571
PathwayWP_INTEGRINMEDIATED_CELL_ADHESION

ITGB2 ITGB3 ITGB6 ITGB8

1.18e-03102644M39577
PathwayWP_INTEGRINMEDIATED_CELL_ADHESION

ITGB2 ITGB3 ITGB6 ITGB8

1.18e-03102644MM15830
PathwayWP_NOTCH_SIGNALING_PATHWAY

DLL3 NOTCH2 NOTCH4

1.18e-0346643MM15971
PathwayREACTOME_TGF_BETA_RECEPTOR_SIGNALING_ACTIVATES_SMADS

ITGB3 ITGB6 ITGB8

1.25e-0347643M646
PathwayKEGG_NOTCH_SIGNALING_PATHWAY

DLL3 NOTCH2 NOTCH4

1.25e-0347643M7946
PathwayKEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00380

NOTCH2 NOTCH4

1.30e-0312642M47532
PathwayKEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00381

NOTCH2 NOTCH4

1.30e-0312642M47533
PathwayREACTOME_O_LINKED_GLYCOSYLATION

ADAMTS7 MUC5B SSPOP GALNT4

1.50e-03109644MM15164
PathwayKEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00382

NOTCH2 NOTCH4

1.53e-0313642M47534
PathwayWP_FOCAL_ADHESION

PDGFC ITGB2 ITGB3 ITGB6 ITGB8

1.58e-03187645MM15913
PathwayREACTOME_O_LINKED_GLYCOSYLATION

ADAMTS7 MUC5B SSPOP GALNT4

1.61e-03111644M27416
PathwayREACTOME_OTHER_SEMAPHORIN_INTERACTIONS

PLXNA1 PLXNB3

1.78e-0314642MM15047
PathwayWP_OSTEOCLAST_SIGNALING

ITGB3 TRPV5

1.78e-0314642MM15987
PathwayWP_OSTEOBLAST_DIFFERENTIATION_AND_RELATED_DISEASES

DLL3 LRP5 NOTCH2 NOTCH4

2.01e-03118644M39852
PathwayWP_GPR40_PATHWAY

PKD1 PLCD1

2.05e-0315642M39526
PathwayREACTOME_LAMININ_INTERACTIONS

NID2 MEGF6

2.05e-0315642MM14922
PathwayWP_HIPPOMERLIN_SIGNALING_DYSREGULATION

ITGB2 ITGB3 ITGB6 ITGB8

2.21e-03121644M39823
PathwayKEGG_MEDICUS_VARIANT_NOTCH_OVEREXPRESSION_TO_NOTCH_SIGNALING_PATHWAY

DLL3 NOTCH4

2.34e-0316642M47424
PathwayWP_OSTEOCLAST_SIGNALING

ITGB3 TRPV5

2.34e-0316642M39694
PathwayPID_INTEGRIN5_PATHWAY

ITGB6 ITGB8

2.64e-0317642M212
PathwayWP_NOTCH_SIGNALING_WP61

DLL3 NOTCH2 NOTCH4

2.66e-0361643M39540
PathwayKEGG_REGULATION_OF_ACTIN_CYTOSKELETON

PDGFC ITGB2 ITGB3 ITGB6 ITGB8

2.78e-03213645M18306
PathwayKEGG_AXON_GUIDANCE

PLXNA3 SLIT1 PLXNA1 PLXNB3

2.78e-03129644M5539
PathwayREACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI

NOTCH2 NOTCH4

2.96e-0318642M614
PathwayREACTOME_NOTCH4_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION

NOTCH2 NOTCH4

3.66e-0320642M27881
Pubmed

The expression of plexins during mouse embryogenesis.

PLXNA3 PLXNA4 PLXNA1 PLXNB3

1.71e-09879415661641
Pubmed

Transmembrane semaphorin signalling controls laminar stratification in the mammalian retina.

PLXNA3 PLXNA4 PLXNA1 PLXNB3

1.20e-081279421270798
Pubmed

Plexins are a large family of receptors for transmembrane, secreted, and GPI-anchored semaphorins in vertebrates.

PLXNA3 PLXNA4 PLXNA1 PLXNB3

1.74e-081379410520995
Pubmed

Chromosome assignment of four plexin A genes (Plxna1, Plxna2, Plxna3, Plxna4) in mouse, rat, Syrian hamster and Chinese hamster.

PLXNA3 PLXNA4 PLXNA1

4.50e-08479311306810
Pubmed

PlexinA polymorphisms mediate the developmental trajectory of human corpus callosum microstructure.

PLXNA3 PLXNA4 PLXNA1

4.50e-08479325518740
Pubmed

Plexin-A3 mediates semaphorin signaling and regulates the development of hippocampal axonal projections.

PLXNA3 PLXNA4 PLXNA1 PLXNB3

5.74e-081779411683995
Pubmed

Segmental expression of Notch and Hairy genes in nephrogenesis.

DLL3 DLK1 NOTCH2 NOTCH4

5.74e-081779415821257
Pubmed

Semaphorin signaling facilitates cleft formation in the developing salivary gland.

PLXNA3 PLXNA4 PLXNA1 PLXNB3

5.74e-081779417626059
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

PLXNA3 FAT4 FBN2 MEGF8 KIAA0319L LRP5 GRN TWSG1 LRP1B ITGB8 PLXNA1 ALG1 GALNT4 NOTCH2 PCYOX1

7.38e-081201791535696571
Pubmed

Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins.

GPR62 LRP1B ITGB2 ITGB3 ITGB6 NOTCH2

1.21e-0710179623382219
Pubmed

Targeting of αv integrin identifies a core molecular pathway that regulates fibrosis in several organs.

ITGB3 ITGB6 ITGB8

2.24e-07679324216753
Pubmed

Semaphorin-6A controls guidance of corticospinal tract axons at multiple choice points.

PLXNA3 PLXNA4 PLXNA1

3.92e-07779319063725
Pubmed

Increased proximal bifurcation of CA1 pyramidal apical dendrites in sema3A mutant mice.

PLXNA3 PLXNA4 PLXNA1

3.92e-07779319655386
Pubmed

Perlecan regulates pericyte dynamics in the maintenance and repair of the blood-brain barrier.

ITGB2 ITGB3 ITGB6 ITGB8

4.16e-072779431541017
Pubmed

Expression of Robo/Slit and Semaphorin/Plexin/Neuropilin family members in the developing hypothalamic paraventricular and supraoptic nuclei.

PLXNA3 SLIT1 PLXNA4 PLXNA1

4.84e-072879418617019
Pubmed

Notch signaling in stomach epithelial stem cell homeostasis.

DLL3 DLK1 NOTCH2 NOTCH4

5.61e-072979421402740
Pubmed

Integration of opposing semaphorin guidance cues in cortical axons.

PLXNA3 PLXNA4 PLXNA1

6.27e-07879322368082
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

DIP2A FAT4 MEGF6 PKD1 PLXNA4 ANAPC11 GRN TWSG1 SSPOP FBN3 PLXNB3

8.66e-07736791129676528
Pubmed

Identification of high-molecular-weight proteins with multiple EGF-like motifs by motif-trap screening.

MEGF6 MEGF8 SLIT1

9.38e-0797939693030
Pubmed

Dynamic expression patterns of the pudgy/spondylocostal dysostosis gene Dll3 in the developing nervous system.

DLL3 NOTCH2 NOTCH4

9.38e-07979311118901
Pubmed

Notch1 signals through Jagged2 to regulate apoptosis in the apical ectodermal ridge of the developing limb bud.

DLL3 NOTCH2 NOTCH4

9.38e-07979316245338
Pubmed

The role of neuropilins in cell signalling.

PLXNA3 PLXNA4 PLXNA1

9.38e-07979319909241
Pubmed

Plexin A3 and plexin A4 convey semaphorin signals during facial nerve development.

PLXNA3 PLXNA4 PLXNA1

1.34e-061079318804103
Pubmed

Spatiotemporal expression of Notch receptors and ligands in developing mouse placenta.

DLL3 NOTCH2 NOTCH4

1.34e-061079323665443
Pubmed

Localisation of members of the notch system and the differentiation of vibrissa hair follicles: receptors, ligands, and fringe modulators.

DLL3 NOTCH2 NOTCH4

1.84e-061179310878608
Pubmed

Foxp1/4 control epithelial cell fate during lung development and regeneration through regulation of anterior gradient 2.

DLL3 MUC5B NOTCH2 NOTCH4

2.34e-064179422675208
Pubmed

Functional loss of semaphorin 3C and/or semaphorin 3D and their epistatic interaction with ret are critical to Hirschsprung disease liability.

PLXNA3 PLXNA4 PLXNA1

2.45e-061279325839327
Pubmed

PLXNA1 and PLXNA3 cooperate to pattern the nasal axons that guide gonadotropin-releasing hormone neurons.

PLXNA3 PLXNA4 PLXNA1

2.45e-061279331690636
Pubmed

On and off retinal circuit assembly by divergent molecular mechanisms.

PLXNA3 PLXNA4 PLXNA1

2.45e-061279324179230
Pubmed

Integrins.

ITGB2 ITGB3 ITGB6

2.45e-061279319693543
Pubmed

Deletion of Sema3a or plexinA1/plexinA3 causes defects in sensory afferent projections of statoacoustic ganglion neurons.

PLXNA3 PLXNA4 PLXNA1

2.45e-061279323991118
Pubmed

Developmental expression of the Notch signaling pathway genes during mouse preimplantation development.

DLL3 NOTCH2 NOTCH4

2.45e-061279315465494
Pubmed

Transcriptome profiling reveals expression signatures of cranial neural crest cells arising from different axial levels.

PLXNA3 PLXNA4 PLXNA1

2.45e-061279328407732
Pubmed

Functional assembly of accessory optic system circuitry critical for compensatory eye movements.

PLXNA3 PLXNA4 PLXNA1

3.17e-061379325959730
Pubmed

Vascular expression of Notch pathway receptors and ligands is restricted to arterial vessels.

DLL3 NOTCH2 NOTCH4

3.17e-061379311578869
Pubmed

Plexin signaling via off-track and rho family GTPases.

PLXNA3 PLXNA4 PLXNA1

3.17e-061379311604131
Pubmed

Semaphorin3A, Neuropilin-1, and PlexinA1 are required for lymphatic valve formation.

PLXNA3 PLXNA4 PLXNA1

3.17e-061379322723296
Pubmed

A midline switch of receptor processing regulates commissural axon guidance in vertebrates.

PLXNA3 PLXNA4 PLXNA1

4.03e-061479320159958
Pubmed

Math1 controls cerebellar granule cell differentiation by regulating multiple components of the Notch signaling pathway.

DLL3 NOTCH2 NOTCH4

4.03e-061479314757642
Pubmed

TrkB-dependent EphrinA reverse signaling regulates callosal axon fasciculate growth downstream of Neurod2/6.

PLXNA3 SLIT1 PLXNA4 PLXNA1

4.08e-064779435462405
Pubmed

Expression of Notch pathway genes in the embryonic mouse metanephros suggests a role in proximal tubule development.

DLL3 NOTCH2 NOTCH4

5.03e-061579312971992
Pubmed

New low-frequency platelet glycoprotein polymorphisms associated with neonatal alloimmune thrombocytopenia.

ITGB2 ITGB3

5.09e-06279219821948
Pubmed

Receptor-binding domain of SARS-CoV-2 is a functional αv-integrin agonist.

ITGB3 ITGB6

5.09e-06279236669646
Pubmed

Notch receptors and hematopoiesis.

NOTCH2 NOTCH4

5.09e-06279211532344
Pubmed

Fusion of epithelial cells by Epstein-Barr virus proteins is triggered by binding of viral glycoproteins gHgL to integrins alphavbeta6 or alphavbeta8.

ITGB6 ITGB8

5.09e-06279219920174
Pubmed

Quantitative proteome analysis of alveolar type-II cells reveals a connection of integrin receptor subunits beta 2/6 and WNT signaling.

ITGB2 ITGB6

5.09e-06279224175614
Pubmed

Expression of integrin cell adhesion receptors during human airway epithelial repair in vivo.

ITGB6 ITGB8

5.09e-0627929252563
Pubmed

A refinement to the formalin test in mice.

SLIT1 PINK1

5.09e-06279231489182
Pubmed

The Tat protein of the caprine arthritis encephalitis virus interacts with the Notch2 EGF-like repeats and the epithelin/granulin precursor.

GRN NOTCH2

5.09e-06279212931033
Pubmed

Distinct cytoplasmic domains in Plexin-A4 mediate diverse responses to semaphorin 3A in developing mammalian neurons.

PLXNA3 PLXNA4

5.09e-06279224619647
Pubmed

notch2, notch4 gene polymorphisms in psoriasis vulgaris.

NOTCH2 NOTCH4

5.09e-06279223587900
Pubmed

Inflammation dysregulates Notch signaling in endothelial cells: implication of Notch2 and Notch4 to endothelial dysfunction.

NOTCH2 NOTCH4

5.09e-06279220643108
Pubmed

Comparative proteomic analysis of supportive and unsupportive extracellular matrix substrates for human embryonic stem cell maintenance.

NID2 FBN2 COL26A1 ITGB3

5.24e-065079423658023
Pubmed

An extracellular biochemical screen reveals that FLRTs and Unc5s mediate neuronal subtype recognition in the retina.

PLXNA3 PLXNA4 PLXNA1 PLXNB3

6.14e-065279426633812
Pubmed

Expression of Notch pathway components in fetal and adult mouse small intestine.

DLL3 NOTCH2 NOTCH4

6.18e-061679312617809
Pubmed

Allocation of paraventricular and supraoptic neurons requires Sim1 function: a role for a Sim1 downstream gene PlexinC1.

PLXNA3 PLXNA4 PLXNA1

6.18e-061679317356169
Pubmed

Requirement of Math1 for secretory cell lineage commitment in the mouse intestine.

DLL3 NOTCH2 NOTCH4

6.18e-061679311739954
Pubmed

Expression of the semaphorins Sema 3D and Sema 3F in the developing parathyroid and thymus.

PLXNA3 PLXNA4 PLXNA1

6.18e-061679318489001
Pubmed

Gamma-secretase activation of notch signaling regulates the balance of proximal and distal fates in progenitor cells of the developing lung.

DLL3 NOTCH2 NOTCH4

7.50e-061779318694942
Pubmed

Unravelling differential Hes1 dynamics during axis elongation of mouse embryos through single-cell tracking.

DLL3 NOTCH2 NOTCH4

7.50e-061779339315665
Pubmed

Comparison of an expanded ataxia interactome with patient medical records reveals a relationship between macular degeneration and ataxia.

NELL1 MEGF6 MEGF8 SCP2 GRN

7.61e-0611879521078624
Pubmed

RBPjkappa-dependent Notch function regulates Gata2 and is essential for the formation of intra-embryonic hematopoietic cells.

DLL3 NOTCH2 NOTCH4

8.98e-061879315689374
Pubmed

A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.

NELL1 FAT4 COL26A1 MEGF6 MEGF8 SLIT1 GRN SSPOP MEGF11

9.97e-0660879916713569
Pubmed

Neurovascular EGFL7 regulates adult neurogenesis in the subventricular zone and thereby affects olfactory perception.

DLL3 NOTCH2 NOTCH4

1.46e-052179328656980
Pubmed

Structural Basis for Plexin Activation and Regulation.

PLXNA4 PLXNA1

1.53e-05379227397516
Pubmed

Identification of plexin family molecules in mice.

PLXNA3 PLXNA1

1.53e-0537928806646
Pubmed

αVβ8 integrin targeting to prevent posterior capsular opacification.

ITGB6 ITGB8

1.53e-05379234554928
Pubmed

Repulsive and attractive semaphorins cooperate to direct the navigation of cardiac neural crest cells.

PLXNA4 PLXNA1

1.53e-05379218625214
Pubmed

EGFL7 participates in regulating biological behavior of growth hormone-secreting pituitary adenomas via Notch2/DLL3 signaling pathway.

DLL3 NOTCH2

1.53e-05379228705113
Pubmed

Differential expression of plexin-A subfamily members in the mouse nervous system.

PLXNA3 PLXNA1

1.53e-05379211241833
Pubmed

Differential expression of Notch genes in human osteoblastic cells.

NOTCH2 NOTCH4

1.53e-05379211836628
Pubmed

Plexin signaling selectively regulates the stereotyped pruning of corticospinal axons from visual cortex.

PLXNA3 PLXNA4

1.53e-05379218523013
Pubmed

Increased Expressions of Integrin Subunit β1, β2 and β3 in Patients with Acute Infection.

ITGB2 ITGB3

1.53e-05379226283883
Pubmed

ADAMTS-7, a direct target of PTHrP, adversely regulates endochondral bone growth by associating with and inactivating GEP growth factor.

ADAMTS7 GRN

1.53e-05379219487464
Pubmed

αvβ6- and αvβ8-integrins serve as interchangeable receptors for HSV gH/gL to promote endocytosis and activation of membrane fusion.

ITGB6 ITGB8

1.53e-05379224367260
Pubmed

The EGF-like homeotic protein dlk affects cell growth and interacts with growth-modulating molecules in the yeast two-hybrid system.

GRN DLK1

1.53e-05379211846389
Pubmed

Integrity of intracellular domain of Notch ligand is indispensable for cleavage required for release of the Notch2 intracellular domain.

NOTCH2 NOTCH4

1.53e-05379211823422
Pubmed

A novel form of integrin dysfunction involving beta1, beta2, and beta3 integrins.

ITGB2 ITGB3

1.53e-05379212511588
Pubmed

Notch signaling: cell fate control and signal integration in development.

NOTCH2 NOTCH4

1.53e-05379210221902
Pubmed

Dissociation of HSV gL from gH by αvβ6- or αvβ8-integrin promotes gH activation and virus entry.

ITGB6 ITGB8

1.53e-05379226157134
Pubmed

Integrins as triggers of Epstein-Barr virus fusion and epithelial cell infection.

ITGB6 ITGB8

1.53e-05379221178476
Pubmed

Interaction of alphaVbeta3 and alphaVbeta6 integrins with human parechovirus 1.

ITGB3 ITGB6

1.53e-05379220554778
Pubmed

Integrin expression and glycosylation patterns regulate cell-matrix adhesion and alter with breast cancer progression.

ITGB3 ITGB6

1.53e-05379229577899
Pubmed

No association between hip geometry and four common polymorphisms associated with fracture: the Danish osteoporosis prevention study.

P2RX7 LRP5

1.53e-05379219225709
Pubmed

Pharmacologic Blockade of αvβ1 Integrin Ameliorates Renal Failure and Fibrosis In Vivo.

ITGB3 ITGB8

1.53e-05379228220032
Pubmed

Myeloid translocation gene 16b is a dual A-kinase anchoring protein that interacts selectively with plexins in a phospho-regulated manner.

PLXNA3 PLXNA1

1.53e-05379220138877
Pubmed

The PINK1 p.Asn521Thr Variant Is Associated with Earlier Disease Onset in GRN/C9orf72 Frontotemporal Lobar Degeneration.

GRN PINK1

1.53e-05379236361641
Pubmed

The gene organization of the human beta 7 subunit, the common beta subunit of the leukocyte integrins HML-1 and LPAM-1.

ITGB3 ITGB6

1.53e-0537921382574
Pubmed

Notch promotes epithelial-mesenchymal transition during cardiac development and oncogenic transformation.

DLL3 NOTCH2 NOTCH4

1.93e-052379314701881
Pubmed

A semaphorin code defines subpopulations of spinal motor neurons during mouse development.

PLXNA3 PLXNA4 PLXNA1

2.21e-052479315869472
Pubmed

A radial axis defined by semaphorin-to-neuropilin signaling controls pancreatic islet morphogenesis.

PLXNA3 PLXNA4 PLXNA1

2.21e-052479328893946
Pubmed

Hepatic Notch2 deficiency leads to bile duct agenesis perinatally and secondary bile duct formation after weaning.

DLK1 NOTCH2 NOTCH4

2.82e-052679325446530
Pubmed

Prognostic roles of mRNA expression of notch receptors in non-small cell lung cancer.

NOTCH2 NOTCH4

3.05e-05479228061457
Pubmed

The 4 Notch receptors play distinct and antagonistic roles in the proliferation and hepatocytic differentiation of liver progenitors.

NOTCH2 NOTCH4

3.05e-05479224145721
Pubmed

Integrin alpha v beta 8. Interaction with vitronectin and functional divergence of the beta 8 cytoplasmic domain.

ITGB3 ITGB8

3.05e-0547927525578
Pubmed

A switch in Notch gene expression parallels stem cell to endothelial transition in infantile hemangioma.

NOTCH2 NOTCH4

3.05e-05479220069356
Pubmed

ATP release into ADPKD cysts via pannexin-1/P2X7 channels decreases ENaC activity.

P2RX7 PKD1

3.05e-05479230952430
Pubmed

Expression and clinical significance of Notch receptors in human renal cell carcinoma.

NOTCH2 NOTCH4

3.05e-05479219404845
Pubmed

Notch signaling pathway regulates the growth and the expression of inflammatory cytokines in mouse basophils.

NOTCH2 NOTCH4

3.05e-05479228669409
Pubmed

P2RX7 sensitizes Mac-1/ICAM-1-dependent leukocyte-endothelial adhesion and promotes neurovascular injury during septic encephalopathy.

P2RX7 ITGB2

3.05e-05479225998681
InteractionIGFL3 interactions

FBN2 ADAMTS7 LMLN LRP5 GRN LOXL3 LRP1B NOTCH2

3.86e-1075768int:IGFL3
InteractionSEMA5A interactions

PLXNA3 PLXNA4 PLXNA1 PLXNB3

6.48e-097764int:SEMA5A
InteractionFBXO2 interactions

PLXNA3 NID2 FBN2 MEGF8 ADAMTS7 KIAA0319L GRN LRP1B PLXNA1 NOTCH2 PCYOX1 CEMIP

4.22e-084117612int:FBXO2
InteractionSLURP1 interactions

PLXNA3 NID2 MEGF8 ADAMTS7 LMLN GRN PLXNA1 NOTCH2

6.99e-08144768int:SLURP1
InteractionTAFAZZIN interactions

PLXNA3 NID2 MEGF8 ADAMTS7 LMLN LRP5 LRP1B PLXNA1

1.12e-06207768int:TAFAZZIN
InteractionATN1 interactions

NELL1 MEGF6 MEGF8 SLIT1 GRN SSPOP MEGF11

6.74e-06187767int:ATN1
InteractionCFC1 interactions

MEGF8 ADAMTS7 LRP5 PLXNA1 NOTCH2 CEMIP

8.10e-06126766int:CFC1
InteractionEGFL7 interactions

NELL1 GRN DLK1 NOTCH2 NOTCH4

1.07e-0577765int:EGFL7
InteractionIQUB interactions

DIP2A KRT40 ANAPC11 PLCD1 VSIG8

1.29e-0580765int:IQUB
InteractionCRISP2 interactions

PLXNA3 ADAMTS7 LRP5 PLXNA1

1.54e-0540764int:CRISP2
InteractionSIRPD interactions

PLXNA3 MEGF8 ADAMTS7 LRP5 PLXNA1

1.83e-0586765int:SIRPD
InteractionDEFB135 interactions

PLXNA3 ATRNL1 LRP5 LRP1B

1.87e-0542764int:DEFB135
InteractionSEMA5B interactions

PLXNA3 PLXNA4 PLXNA1

2.27e-0515763int:SEMA5B
InteractionTIMP3 interactions

NELL1 ADAMTS7 LRP5 LRP1B NOTCH2

2.28e-0590765int:TIMP3
InteractionDLK1 interactions

DIP2A GRN DLK1 NOTCH2 PCYOX1

3.99e-05101765int:DLK1
InteractionMAML3 interactions

NID2 NOTCH2 NOTCH4

5.61e-0520763int:MAML3
InteractionRNF123 interactions

DIP2A FAT4 MEGF6 PKD1 PLXNA4 ANAPC11 GRN TWSG1 SSPOP GRSF1 FBN3 PLXNB3

5.63e-058247612int:RNF123
InteractionHOXA1 interactions

NELL1 MEGF6 MEGF8 SLIT1 KRT40 SIVA1 GRN PCYOX1

5.81e-05356768int:HOXA1
InteractionZFP41 interactions

FBN2 GRN LRP1B NOTCH2

6.34e-0557764int:ZFP41
InteractionLYPD1 interactions

MEGF8 ADAMTS7 LRP5 NOTCH2

6.79e-0558764int:LYPD1
InteractionCLEC12B interactions

PLXNA3 LMLN KIAA0319L PLXNA1 GALNT4 GP1BB

6.87e-05184766int:CLEC12B
InteractionKLK3 interactions

PLXNA3 ADAMTS7 LRP5 GRN

7.76e-0560764int:KLK3
InteractionSEMA6D interactions

PLXNA3 PLXNA4 PLXNA1

8.65e-0523763int:SEMA6D
InteractionDNASE1L1 interactions

PLXNA3 MEGF8 ADAMTS7 PLXNA1 CEMIP

9.07e-05120765int:DNASE1L1
InteractionNTN5 interactions

FBN2 LRP1B NOTCH2

9.85e-0524763int:NTN5
InteractionLYPD4 interactions

PLXNA3 LRWD1 FBN2 ADAMTS7 LMLN

1.02e-04123765int:LYPD4
InteractionCACNA1A interactions

NELL1 MEGF6 MEGF8 SCP2 GRN

1.02e-04123765int:CACNA1A
InteractionIL5RA interactions

PLXNA3 MEGF8 ADAMTS7 LRP5 PLXNA1

1.06e-04124765int:IL5RA
InteractionCBLN4 interactions

PLXNA3 MEGF8 ADAMTS7 PLXNA1 CEMIP

1.19e-04127765int:CBLN4
InteractionCA6 interactions

PLXNA3 ADAMTS7 KRT40 PLXNA1

1.34e-0469764int:CA6
InteractionFIBIN interactions

PLXNA3 MEGF8 ADAMTS7 PLXNA1

1.50e-0471764int:FIBIN
InteractionNMS interactions

LRP5 VSIG8 LRP1B

1.94e-0430763int:NMS
InteractionZNF408 interactions

FBN2 KRT40 GRN LRP1B NOTCH2

2.21e-04145765int:ZNF408
InteractionPI15 interactions

ADAMTS7 KIAA0319L LRP5 PLXNA1

2.74e-0483764int:PI15
InteractionCELA2B interactions

ADAMTS7 KRT40 GRN

2.84e-0434763int:CELA2B
InteractionST8SIA4 interactions

PLXNA3 KIAA0319L LRP5 PLXNA1

2.87e-0484764int:ST8SIA4
InteractionCOL15A1 interactions

GRSF1 PINK1

2.91e-047762int:COL15A1
InteractionNDP interactions

ADAMTS7 LRP5 LRP1B

3.09e-0435763int:NDP
InteractionZNF446 interactions

DPH7 KRT40 SIVA1 NOTCH2

3.43e-0488764int:ZNF446
InteractionMGAT4C interactions

KIAA0319L LRP5 PLXNA1

3.95e-0438763int:MGAT4C
InteractionC1QB interactions

PLXNA3 ADAMTS7 PLXNA1 PINK1

4.40e-0494764int:C1QB
InteractionHSPG2 interactions

NID2 GRN GPC5 LOXL3

5.16e-0498764int:HSPG2
InteractionPTPRK interactions

PLXNA3 NID2 MEGF8 LRP1B PLXNA1

5.51e-04177765int:PTPRK
GeneFamilyCD molecules|Integrin beta subunits

ITGB2 ITGB3 ITGB6 ITGB8

4.18e-0994541159
GeneFamilyPlexins

PLXNA3 PLXNA4 PLXNA1 PLXNB3

4.18e-099454683
GeneFamilyLow density lipoprotein receptors

LRP5 LRP1B

4.64e-0413452634
GeneFamilyAnkyrin repeat domain containing

ACAP2 TRPV5 NOTCH2 NOTCH4

3.03e-03242454403
GeneFamilyHyalectan proteoglycans|V-set domain containing|Sushi domain containing|C-type lectin domain containing

ATRNL1 PKD1

4.67e-03414521298
CoexpressionNABA_MATRISOME

PLXNA3 NELL1 NID2 FBN2 COL26A1 MEGF6 MEGF8 ADAMTS7 SLIT1 PLXNA4 KCP MUC5B GPC5 LOXL3 PDGFC SSPOP MEGF11 PLXNA1 FBN3 PLXNB3

1.76e-1110267920M5889
CoexpressionNABA_MATRISOME

PLXNA3 NELL1 NID2 FBN2 COL26A1 MEGF6 MEGF8 ADAMTS7 SLIT1 PLXNA4 KCP MUC5B GPC5 LOXL3 PDGFC SSPOP MEGF11 PLXNA1 PLXNB3

1.10e-1010087919MM17056
CoexpressionNABA_CORE_MATRISOME

NELL1 NID2 FBN2 COL26A1 SLIT1 KCP SSPOP FBN3

1.82e-06275798M5884
CoexpressionNABA_MATRISOME_ASSOCIATED

PLXNA3 MEGF6 MEGF8 ADAMTS7 PLXNA4 MUC5B GPC5 LOXL3 PDGFC MEGF11 PLXNA1 PLXNB3

2.07e-067387912MM17058
CoexpressionNABA_ECM_GLYCOPROTEINS

NELL1 NID2 FBN2 SLIT1 KCP SSPOP FBN3

2.16e-06196797M3008
CoexpressionNABA_MATRISOME_ASSOCIATED

PLXNA3 MEGF6 MEGF8 ADAMTS7 PLXNA4 MUC5B GPC5 LOXL3 PDGFC MEGF11 PLXNA1 PLXNB3

2.48e-067517912M5885
CoexpressionMEISSNER_BRAIN_HCP_WITH_H3K4ME3_AND_H3K27ME3

NELL1 NID2 FAT4 COL26A1 ADAMTS7 LITAF DLL3 PLXNA4 LRP5 CLDN5 GPC5 MEGF11 PEAR1 CEMIP

3.58e-0610747914M1941
CoexpressionNABA_ECM_AFFILIATED

PLXNA3 PLXNA4 MUC5B GPC5 PLXNA1 PLXNB3

8.43e-06158796MM17063
CoexpressionNABA_ECM_AFFILIATED

PLXNA3 PLXNA4 MUC5B GPC5 PLXNA1 PLXNB3

1.28e-05170796M5880
CoexpressionFUKUSHIMA_TNFSF11_TARGETS

DLL3 NOTCH2 NOTCH4

1.43e-0516793MM1296
CoexpressionFUKUSHIMA_TNFSF11_TARGETS

DLL3 NOTCH2 NOTCH4

1.43e-0516793M2207
CoexpressionHE_LIM_SUN_FETAL_LUNG_C0_MESENCHYMAL_3_CELL

FBN2 COL26A1 DLK1 ITGB8 FBN3 PINK1

1.46e-05174796M45676
CoexpressionNABA_CORE_MATRISOME

NELL1 NID2 FBN2 COL26A1 SLIT1 KCP SSPOP

1.75e-05270797MM17057
CoexpressionGSE32255_UNSTIM_VS_4H_LPS_STIM_DC_UP

PLXNA3 P2RX7 TWSG1 PLCD1 ITGB8 PEAR1

2.13e-05186796M8914
CoexpressionNABA_ECM_GLYCOPROTEINS

NELL1 NID2 FBN2 SLIT1 KCP SSPOP

2.47e-05191796MM17059
CoexpressionLI_ESTROGENE_LATE_E2_RESPONSE_DN

FBN2 SSPOP ITGB6 CEMIP

1.02e-0480794M48218
CoexpressionVART_KSHV_INFECTION_ANGIOGENIC_MARKERS_UP

DLL3 DLK1 ITGB3 NOTCH2 NOTCH4

1.36e-04163795M12112
CoexpressionZHONG_PFC_C3_ASTROCYTE

PLXNA3 MEGF6 SLIT1 PKD1 PLXNA4 CLDN5 FBN3

1.74e-04389797M39102
ToppCell10x5'-lymph-node_spleen-Hematopoietic_Erythro-Mega|lymph-node_spleen / Manually curated celltypes from each tissue

CLDN5 DLK1 ITGB3 PLXNB3 PEAR1 GP1BB

6.98e-071757965ca3369ce2c2bb88ba097260195aecd67cec1a3a
ToppCell10x5'-lymph-node_spleen-Hematopoietic_Erythro-Mega-Megakaryocyte_early|lymph-node_spleen / Manually curated celltypes from each tissue

CLDN5 DLK1 ITGB3 PLXNB3 PEAR1 GP1BB

7.22e-0717679650fe3fd862dd6a6550ebb8c27f337cde468efedc
ToppCell3'_v3-blood-Hematopoietic_Erythro-Mega-Megakaryocyte_early|blood / Manually curated celltypes from each tissue

CLDN5 DLK1 GPC5 ITGB3 PEAR1 GP1BB

7.97e-07179796290772eece76d70555dca8b8d82bd88b47e2fc35
ToppCell3'_v3-blood-Hematopoietic_Erythro-Mega|blood / Manually curated celltypes from each tissue

CLDN5 DLK1 GPC5 ITGB3 PEAR1 GP1BB

8.78e-071827963100165c5ba8c3016f9a2f7a8e4ea136750823fe
ToppCell3'_v3-bone_marrow-Hematopoietic_Erythro-Mega-Megakaryocyte_early|bone_marrow / Manually curated celltypes from each tissue

CLDN5 DLK1 PDGFC ITGB3 PEAR1 GP1BB

8.78e-071827961a755ea44daf8447a3a1c30de7fdb9c3888bcbde
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NELL1 P2RX7 SLIT1 PLXNA4 LRP1B ITGB8

8.78e-0718279635b2a5625323bf0917214d3b82fafc4a8f5e75ff
ToppCell10x5'v1-week_17-19-Hematopoietic-MK-MK|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

CLDN5 DLK1 ITGB3 PLXNB3 PEAR1 GP1BB

9.06e-071837969c66a40c355387f805dbdca4162dd05af5c1d8d4
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NELL1 P2RX7 PLXNA4 PDGFC LRP1B ITGB8

9.35e-071847969a185e6ea86bbfbb48bfe88650a8c05ceba78d7f
ToppCell10x5'v1-week_17-19-Hematopoietic-MK|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

CLDN5 DLK1 ITGB3 PLXNB3 PEAR1 GP1BB

1.03e-0618779634cad5ac8602fe88ca3d421257190c9a388d4cb0
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-lymphatic_endothelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MEGF6 ADAMTS7 CLDN5 TM4SF18 PEAR1 CEMIP

1.06e-0618879626915db8863f4115b46a81982e187322e21600fd
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MEGF6 ADAMTS7 CLDN5 TM4SF18 PEAR1 CEMIP

1.06e-061887963f76c0f912f8f023ea425be7f43593b3d7f967e3
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MEGF6 ADAMTS7 CLDN5 TM4SF18 PEAR1 CEMIP

1.06e-0618879661ee7b152745164293d8a44ef91ee2393efbdca5
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Ascending_Thin_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FCGBP FBN2 COL26A1 PLXNA4 GPC5 ITGB8

1.13e-0619079659bbbd2c8d4b7ce46c54ca8022b1557e7e5eee2a
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_arterial-G|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NID2 ADAMTS7 CLDN5 TM4SF18 NOTCH4 PEAR1

1.39e-06197796a312d9cf4ced949307eb9620be4eed926300b892
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_arterial-F|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NID2 ADAMTS7 CLDN5 TM4SF18 NOTCH4 PEAR1

1.48e-06199796463ba77dc4c85eebb343f29a42c7ac889b0497c9
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW16-Macroglial|GW16 / Sample Type, Dataset, Time_group, and Cell type.

P2RX7 LITAF PLCD1 ITGB8 NOTCH2 NOTCH4

1.52e-0620079625b573f4427ecafe050ca90bea459f1b25b451cf
ToppCellASK454-Epithelial-Type_2|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq

MEGF8 LMLN PLCD1 ITGB8 PLXNA1

4.41e-06136795ff9a5e111993fdb3ac64c5ef269e3460ff994517
ToppCellLPS-IL1RA+antiTNF-Unknown-Endothelial-Pericyte_2|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KCP GPC5 TM4SF18 PDGFC PLXNB3

4.91e-061397952fb51abb3ce88c21726c026d6365b2582e2e79f6
ToppCellGlobus_pallidus-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Pappa2_(Mural.Rgs5Acta2.Pappa2)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

MKKS PDGFC ITGB3 PTGIR GPR179

5.27e-06141795a32947b13e888850c979a54c137512e4b96d2f36
ToppCellGlobus_pallidus-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Pappa2_(Mural.Rgs5Acta2.Pappa2)-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

MKKS PDGFC ITGB3 PTGIR GPR179

5.27e-061417952cb651d63466fdcce011d1dd8de409ef439d03e7
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN2 KCP ASTN1 MUC5B LRP1B

9.74e-06160795c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN2 KCP ASTN1 MUC5B LRP1B

9.74e-0616079525c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellfacs-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NID2 SLIT1 PDGFC PLXNA1 PLXNB3

1.23e-0516879504e168fe1d6f5f9e3d3bf9d7c13e800e3594868a
ToppCellILEUM-non-inflamed-(3)_MNP-(3)_mature_DC|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

GOLGA8H PTGIR ITGB6 GRSF1 MEGF11

1.34e-05171795341f9f79c1ed654ab347e25dc4936f89ffdf9617
ToppCellEndothelial-B-Donor_06|World / lung cells shred on cell class, cell subclass, sample id

NID2 ADAMTS7 CLDN5 TM4SF18 PEAR1

1.38e-051727958a527dff06d841a86c7eb04a1dd9630787294da4
ToppCellEndothelial-A-IPF_03|World / lung cells shred on cell class, cell subclass, sample id

FAT4 CLDN5 TM4SF18 NOTCH4 PEAR1

1.38e-05172795a3201773a25832e92dd113fad165f1ecd37f5e91
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Degenerative_Ascending_Thin_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FCGBP FBN2 COL26A1 PLXNA4 ITGB2

1.46e-0517479546bd0ef7d0541386de7a901d85d53d0176dc92bf
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6-Exc_L6_THEMIS_LINC00343|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NELL1 SLIT1 PDGFC LRP1B ITGB8

1.59e-05177795921783ed0fe20294d2f384d9136924b679df01bb
ToppCell3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL26A1 ASTN1 DLK1 PTGIR NOTCH2

1.59e-051777957af1a19692f7fe8f691178a4e57d62bc379e3d56
ToppCell368C-Myeloid-Macrophage-SPP1+_Macrophage_3|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

TBC1D13 MEGF6 KCP NOTCH4 CEMIP

1.59e-05177795eb0cfe8e9a91910f9979608ed47add48d98ce4dd
ToppCell368C-Myeloid-Macrophage-SPP1+_Macrophage_3|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

TBC1D13 MEGF6 KCP NOTCH4 CEMIP

1.63e-051787959d575902d3dbe33437c9d4200df093a741269803
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NELL1 SLIT1 PDGFC LRP1B ITGB8

1.67e-051797951ac79c82c52fa95bb4e170ab20fec0f648db2134
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NELL1 SLIT1 PDGFC LRP1B ITGB8

1.67e-05179795445eeb0356d9fd894aa33dd9f45d893b21424149
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Ascending_Thin_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FCGBP FBN2 COL26A1 PLXNA4 ITGB8

1.67e-0517979555bc69f107fc710db7617c428575792adfdbbcc1
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6-Exc_L6_THEMIS_LINC00343|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NELL1 SLIT1 PDGFC LRP1B ITGB8

1.77e-051817959de2f2cc5f02e0ca599c9e0d2cb1e1e4b5aac112
ToppCellPCW_07-8.5-Neuronal-Neuronal_SCP-neuro_SCP_(0)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

P2RX7 DLL3 PLXNA4 DLK1 PLXNB3

1.77e-05181795fad7ba168f541ac9d04edebc206f191e48bb7e99
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6-Exc_L6_THEMIS_LINC00343|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NELL1 P2RX7 PDGFC LRP1B ITGB8

1.81e-05182795cc6f9d606a4f8717dc44928ceec2a257636043fd
ToppCell10x5'-bone_marrow-Hematopoietic_Erythro-Mega-Megakaryocyte_early|bone_marrow / Manually curated celltypes from each tissue

CLDN5 ITGB3 PTGIR PEAR1 GP1BB

1.86e-051837953cc9f3dc3bc4bde1d3408b0a6ba58e135a11036d
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FCGBP FBN2 COL26A1 PLXNA4 ITGB8

1.86e-0518379583592c332b1e82673f993d37c7f480befdc3dcda
ToppCell10x5'v1-week_12-13-Hematopoietic-MK-MK|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

CLDN5 ITGB3 PLXNB3 PEAR1 GP1BB

1.86e-051837956cbc88c27dc957d182526e84824f70c8e860bf74
ToppCell(7)_DC_plasmacytoid|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)

NELL1 COL26A1 PLXNA4 GRN NOTCH4

1.86e-051837952c6475c935b5a90931be6b3c53f1f707cfcd11f4
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 FBN2 MUC5B LRP1B SSPOP

1.91e-051847952cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 FBN2 MUC5B LRP1B SSPOP

1.91e-05184795ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 FBN2 MUC5B LRP1B SSPOP

1.91e-051847952b19a8c5f823e00812908b23e66bb4e563278aff
ToppCelldroplet-Kidney-nan-18m-Epithelial-Pecam____Kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MEGF6 PLXNA4 CLDN5 ITGB3 NOTCH4

2.07e-05187795e93cad16a087d1443cbf4e1690dc1b35d7a84c41
ToppCellCOVID-19-kidney-DCT|COVID-19 / Disease (COVID-19 only), tissue and cell type

NELL1 LRP1B ITGB6 TRPV5 MEGF11

2.12e-051887951d56cd409793f05cca20757ab26e91f1a1ee67b5
ToppCell10x5'v1-week_17-19-Hematopoietic|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

DLK1 ITGB3 PLXNB3 PEAR1 GP1BB

2.12e-05188795c00ba0abd0c7bb2c8f9166a2ac6220aae4f4d857
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NELL1 ATRNL1 PLXNA4 PDGFC NOTCH2

2.17e-0518979545e588b2a4ad9e3ff74e22d9d627ed3571f3b8b8
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FCGBP COL26A1 PLXNA4 GPC5 ITGB8

2.23e-051907951cf023e3c6924d6a06f353d4b62444b6f2fee8a7
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_arterial-C|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NID2 BRWD1-AS2 CLDN5 TM4SF18 NOTCH4

2.23e-0519079506bfb62b94b0faf467ef93d5bc5d08924c770098
ToppCellEndothelial-A-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

FAT4 CLDN5 TM4SF18 NOTCH4 PEAR1

2.29e-05191795f702dfe88a9b04091dae87df61b2b4f43525f86a
ToppCellPCW_07-8.5|World / Celltypes from embryonic and fetal-stage human lung

FBN2 COL26A1 ATRNL1 PDGFC FBN3

2.46e-051947955759c83308df017f1faae248e9b85388e25254f0
ToppCell10x5'-blood-Hematopoietic_Erythro-Mega-Megakaryocyte_early|blood / Manually curated celltypes from each tissue

CLDN5 ITGB3 PTGIR PEAR1 GP1BB

2.46e-0519479563dea7d630962761a70aa88e720ee35c22cbc81a
ToppCell10x5'-blood-Hematopoietic_Erythro-Mega|blood / Manually curated celltypes from each tissue

CLDN5 ITGB3 PTGIR PEAR1 GP1BB

2.46e-05194795d0e7d35b5086834929c4bd39d4c6719b2d5fc71e
ToppCellASK454-Endothelial|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq

FAT4 CLDN5 TM4SF18 NOTCH4 PEAR1

2.59e-0519679514dd6956ef420b660be0baf52a66960e57d75d16
ToppCell10x_3'_v2v3-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia_independent-F|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MEGF8 PKD1 PDGFC PLXNA1 CEMIP

2.59e-05196795b8b9801181d7604871b48aebacb295d0a57a5eaf
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FAT4 CLDN5 GPC5 TM4SF18 NOTCH4

2.59e-05196795e224338490691d92c1f70b57112fabdcc92b06a9
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_immature|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NID2 CLDN5 TM4SF18 NOTCH4 PEAR1

2.65e-0519779562c0a90869431e582bb7bb329e0b0cc59123d3d1
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FAT4 CLDN5 GPC5 TM4SF18 NOTCH4

2.65e-05197795c10dd1aaec01fb662eac83dfde90e3e426665d65
ToppCell10x3'2.3-week_17-19-Endothelial-stroma-tip_EC|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

NID2 CLDN5 TM4SF18 NOTCH4 PEAR1

2.65e-05197795b212ff28ca2d1fea4140f186ab90941bdca21249
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_immature-Tip-like-A|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NID2 CLDN5 TM4SF18 NOTCH4 PEAR1

2.65e-051977959e948b2e0f7e426f1e6f95bbbf4282fbddc2b99d
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FAT4 CLDN5 GPC5 TM4SF18 NOTCH4

2.65e-051977952844dbcd0a673ed81c99920aa45858651a00736d
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_immature-Tip-like|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NID2 CLDN5 TM4SF18 NOTCH4 PEAR1

2.65e-0519779516f0eb047df9d702518f82ee99c6e7dc1350b2fb
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c08-IL2RB|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

DIP2A P2RX7 LITAF SCP2 ITGB2

2.65e-05197795b6689a3e01e4c285fc2cb33f8c437078722a3892
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NID2 COL26A1 MEGF6 DLK1 PTGIR

2.72e-051987959541d68a1a6247dbd7161a62644eea6527c2c8ff
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Endothelial-Endothelial_immature-Tip-like-A|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NID2 CLDN5 TM4SF18 NOTCH4 PEAR1

2.72e-0519879572e8b9cccb7b0a2ea9d415218fff4fa2f09728f4
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Endothelial|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NID2 CLDN5 TM4SF18 NOTCH4 PEAR1

2.72e-05198795e1fa02184ce93c4f8aa5cf04b70949cd4c425ff0
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c01-FCGR3A|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

DIP2A FAT4 P2RX7 LITAF ITGB2

2.72e-051987951a189b2b213099505c5d871fb8aedd55a97d44e0
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_ILC|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

DIP2A FAT4 P2RX7 LITAF ITGB2

2.72e-05198795716c27d2a37b5f865b9d191e1851917340b400af
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_ILC-NK_cell|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

DIP2A FAT4 P2RX7 LITAF ITGB2

2.72e-05198795b12914c3c5b8dd628cb456cb40283c5016641872
ToppCellTracheal-10x3prime_v2-Immune_Myeloid-Macrophage_other-Macro_AW_CX3CR1|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

FCGBP KCP LOXL3 PDGFC ALG1

2.78e-05199795514dbf128b6832b1cbd65be023d4fe02400e8dec
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Endothelial-Endothelial_immature|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NID2 CLDN5 TM4SF18 NOTCH4 PEAR1

2.78e-051997959c40b3ee39860e9d8edafd007daec11abdd95435
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ATRNL1 ASTN1 LRP1B MEGF11 PLXNB3

2.78e-05199795333056c2abe9724efeab542c0365fcfe4eff8f18
ToppCell10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-Scavenging_endothelial|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NID2 CLDN5 TM4SF18 NOTCH4 PEAR1

2.78e-05199795d95d78b2ebc9a20532466e4d4be579b4faf6776f
ToppCell10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-Scavenging_endothelial-F|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NID2 CLDN5 TM4SF18 NOTCH4 PEAR1

2.78e-05199795cdcfca94baba66e213cc3ffb0cfb4c75d6ab44ec
ToppCellBiopsy_Control_(H.)-Mesenchymal-Mesothelial_cells|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

NELL1 NID2 ATRNL1 ASTN1 CEMIP

2.78e-05199795ca970114b5aef4518ce580897a62ac88688b2671
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Endothelial-Endothelial_immature-Tip-like|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NID2 CLDN5 TM4SF18 NOTCH4 PEAR1

2.78e-0519979572b34bce8157abe389e95cd3ed8ba578dce0cbf6
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ATRNL1 ASTN1 LRP1B MEGF11 PLXNB3

2.78e-05199795e60ecbb8fa7bcd3e2ce7d78f6efb2cfd1fd77698
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_immature-Tip-like-G|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NID2 CLDN5 TM4SF18 NOTCH4 PEAR1

2.78e-051997951295f34a350bf48987e2fad411aaac3630efd3f1
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_arterial|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NID2 CLDN5 TM4SF18 NOTCH4 PEAR1

2.78e-051997950602e2b2aa56d106da63bd342a38bef437b4d496
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c05-ZNF683|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

DIP2A P2RX7 LITAF SCP2 ITGB2

2.85e-052007952bd8c35484fe6b0bc0f9314216786baaa97d1e95
ToppCellCOVID-19-COVID-19_Convalescent-Others-Platelet|COVID-19_Convalescent / Disease, condition lineage and cell class

CLDN5 PDGFC ITGB3 PTGIR PEAR1

2.85e-052007955547e7173293fce403706f69331ce3976da73a32
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NID2 CLDN5 TM4SF18 NOTCH4 PEAR1

2.85e-05200795061ba851f941c616ddb462512e826c412881c3ce
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PLXNA3 NELL1 GPC5 TRPV5

9.78e-0513579452b5c664c0b7a303c6084d508748dcb6c38a0c23
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NELL1 GPC5 TRPV5 MEGF11

1.04e-0413779485b3a98039c1f68addad0334aa5b2584f6045aaa
ToppCellE18.5-samps-Mesenchymal-Pericyte-pericyte_D|E18.5-samps / Age Group, Lineage, Cell class and subclass

MEGF6 PLCD1 ALG1 GP1BB

1.43e-04149794dcf68eb25733b5db2893728fe4dca5c7267eb58c
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m-Macroglial-oligodendrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LITAF ANAPC11 LRP1B SSPOP

1.47e-04150794afd651c654e715414eff64cf3a37378d057a56a2
ToppCell356C-Lymphocytic-ILC-ILC-3|356C / Donor, Lineage, Cell class and subclass (all cells)

KDM4C DLL3 PAQR8 TWSG1

1.62e-04154794923f5eb8e9258105dbdbe57a5e7976ef60dae29b
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Rectal_Adenocarcinoma-3|TCGA-Colorectal / Sample_Type by Project: Shred V9

ADAMTS7 ANAPC11 SIVA1 PTGIR

1.71e-04156794b464871ad7c8ce0d58013a27996639eac1e526d8
ToppCell356C-Lymphocytic-ILC-ILC-3|ILC / Donor, Lineage, Cell class and subclass (all cells)

KDM4C PKD1 TWSG1

1.74e-0461793d0b33a48ee2faf68b270f9279c630437f3e8b20b
ToppCellmetastatic_Brain-Fibroblasts-Myofibroblasts|Fibroblasts / Location, Cell class and cell subclass

FBN2 COL26A1 MEGF6 PDGFC

1.79e-04158794ab05f6d7968ccd6d3826cd71b763dbedc83822c3
ToppCellPND01-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PLXNA4 ITGB3 PTGIR GP1BB

1.93e-0416179452556b89808e551540f33a13f57417a6696c2438
ToppCellPND01-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet-Megakaryocyte/Platelet_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PLXNA4 ITGB3 PTGIR GP1BB

1.93e-0416179454f156cf2bd5a6ba9a78ec4e3ee28b89998aec2e
ToppCellPND01-Immune-Immune_Myeloid-Megakaryocyte/Platelet|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PLXNA4 ITGB3 PTGIR GP1BB

1.93e-04161794242891be849a4398fe8bea44875ae1ba57950944
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma|TCGA-Brain / Sample_Type by Project: Shred V9

MEGF8 KIAA0319L SCP2 NOTCH2

1.97e-04162794810881210e015c788814e4fe8d7a24c929cf2621
ToppCell5'-Airway_Nasal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_acinar_cell-SMG_duct|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FCGBP MUC5B LRP1B ITGB8

2.02e-04163794a1fbefe53523a9879a4d4b493071059798b5f917
ToppCell5'-Airway_Nasal_SMG-Epithelial|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FCGBP MUC5B LRP1B ITGB8

2.02e-04163794454a5e87e2f9f66e38cc5aa1b433c47b54c9be42
ToppCell5'-Airway_Nasal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_acinar_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FCGBP MUC5B LRP1B ITGB8

2.02e-04163794d9bd9d90cfa4e85d5ea51f8f3ee14a700571f508
ToppCell5'-Airway_Nasal_SMG-Epithelial-Epithelial_transtional-secretory|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FCGBP MUC5B LRP1B ITGB8

2.02e-04163794f6847f47a8856c0d4136c1af317432d45eccfde9
ToppCell5'-Airway_Nasal_SMG|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FCGBP MUC5B LRP1B ITGB8

2.02e-04163794d8450bf9c6d2ec5dd1472952c9e65f82f995337a
ComputationalGenes in the cancer module 275.

ITGB2 ITGB3 ITGB6

3.95e-0516463MODULE_275
Drugoxypertine

GRN ITGB2 ITGB3 ITGB6 ITGB8

7.48e-0749795CID000004640
Diseaseconnective tissue disease (implicated_via_orthology)

FBN2 FBN3

2.01e-053772DOID:65 (implicated_via_orthology)
Diseaseobesity (implicated_via_orthology)

MKKS FAT4 SCP2 NOTCH2 PLXNB3 NOTCH4

2.15e-05215776DOID:9970 (implicated_via_orthology)
Diseaseautosomal dominant polycystic kidney disease (is_implicated_in)

PKD1 LRP5

4.02e-054772DOID:898 (is_implicated_in)
Diseasecancer (implicated_via_orthology)

ACAP2 ITGB2 ITGB3 ITGB6 NOTCH2 NOTCH4

7.34e-05268776DOID:162 (implicated_via_orthology)
DiseaseNeonatal Alloimmune Thrombocytopenia

ITGB3 GP1BB

1.00e-046772C3853779
DiseaseFNAITP

ITGB3 GP1BB

1.00e-046772C3854603
Diseasepolycystic liver disease (implicated_via_orthology)

PKD1 LRP5

1.40e-047772DOID:0050770 (implicated_via_orthology)
DiseaseAutosomal dominant macrothrombocytopenia

ITGB3 GP1BB

1.40e-047772C4304021
DiseaseTetralogy of Fallot

NELL1 GPC5

2.98e-0410772HP_0001636
Diseaseparental longevity

TBC1D13 NELL1 COL26A1 DLK1 TWSG1 LRP1B CEMIP

3.09e-04494777EFO_0007796
Diseaseresponse to lithium ion

MEGF6 SLIT1 NOTCH4

4.29e-0456773GO_0010226
Diseasedementia (is_implicated_in)

GRN NOTCH4

4.36e-0412772DOID:1307 (is_implicated_in)
Diseaseautosomal dominant polycystic kidney disease (implicated_via_orthology)

PKD1 LRP5

5.99e-0414772DOID:898 (implicated_via_orthology)
DiseaseVan Buchem disease

DLL3 LRP5

8.91e-0417772C0432272
Diseasealpha-tocopherol measurement

KDM4C GPC5

1.24e-0320772EFO_0007898
DiseaseHodgkins lymphoma

FCGBP DLK1 MEGF11

1.30e-0382773EFO_0000183
Diseaseserum iron measurement

NELL1 LRP1B NOTCH4

1.50e-0386773EFO_0006332
DiseaseHepatitis

FAT4 LITAF

1.50e-0322772HP_0012115
Diseaseulcerative colitis

LITAF SLIT1 KCP PTGIR NOTCH4

1.85e-03335775EFO_0000729
DiseaseCerebral Astrocytoma

DLL3 NOTCH2

1.94e-0325772C0750935
DiseaseIntracranial Astrocytoma

DLL3 NOTCH2

1.94e-0325772C0750936
DiseasePilocytic Astrocytoma

DLL3 NOTCH2

1.94e-0325772C0334583
DiseaseAstrocytoma

DLL3 NOTCH2

1.94e-0325772C0004114
DiseaseJuvenile Pilocytic Astrocytoma

DLL3 NOTCH2

1.94e-0325772C0280783
DiseaseDiffuse Astrocytoma

DLL3 NOTCH2

1.94e-0325772C0280785
DiseaseGrade I Astrocytoma

DLL3 NOTCH2

1.94e-0325772C1704230
DiseaseSubependymal Giant Cell Astrocytoma

DLL3 NOTCH2

1.94e-0325772C0205768
DiseaseMixed oligoastrocytoma

DLL3 NOTCH2

1.94e-0325772C0547065
DiseaseChildhood Cerebral Astrocytoma

DLL3 NOTCH2

1.94e-0325772C0338070
DiseaseGemistocytic astrocytoma

DLL3 NOTCH2

2.10e-0326772C0334581
DiseaseProtoplasmic astrocytoma

DLL3 NOTCH2

2.10e-0326772C0334580
DiseaseFibrillary Astrocytoma

DLL3 NOTCH2

2.10e-0326772C0334582
DiseaseAnaplastic astrocytoma

DLL3 NOTCH2

2.26e-0327772C0334579
DiseaseDisorder of eye

MKKS LRP5 GRN GPR179

2.33e-03212774C0015397
Diseasecortical surface area measurement

NELL1 FBN2 COL26A1 MEGF6 ADAMTS7 PKD1 TWSG1 PDGFC ITGB8 FBN3

2.55e-0313457710EFO_0010736
DiseaseThrombocytopenia

ITGB3 GP1BB

2.61e-0329772C0040034

Protein segments in the cluster

PeptideGeneStartEntry
LCLGALWDECCDCVG

TWSG1

61

Q9GZX9
LTQGCCYPQAWILAC

LINC00479

61

Q96M42
RCILCNFLPGCWLVG

BRWD1-AS2

26

P59051
GDDCPLVWGQCSHCF

ANAPC11

41

Q9NYG5
PSIAVCWFVGCLCGS

ALG1

136

Q9BT22
CCRLQSGAWGCCPFT

GRN

296

P28799
CCPSLGGSWACCQLP

GRN

456

P28799
PNICASNPCWGDLLC

FAT4

4401

Q6V0I7
ECRCLEGWTGPLCTV

DLL3

236

Q9NYJ7
NASCCDCGLADPRWA

ACAP2

411

Q15057
CATVGRAWGLPCELC

FBN3

211

Q75N90
PGQCICTDGWDGELC

DLK1

71

P80370
CINVPDWRGAICSGC

CEMIP

986

Q8WUJ3
MALAGLCALLACCWG

ASTN1

1

O14525
LCALLACCWGPAAVL

ASTN1

6

O14525
CGENKWCLSGECVPV

ADAMTS7

516

Q9UKP4
SCTCSGGLWQCQDLP

MUC5B

406

Q9HC84
WVLGALLRGCGCNCS

GRSF1

6

Q12849
WLSCGSLCLLGCIAG

LITAF

116

Q99732
DARLLAGCEGGCCCW

LRWD1

456

Q9UFC0
WPGCLLVKRCGGNCA

PDGFC

271

Q9NRA1
QCLCPSGWAGAYCDV

NOTCH2

1086

Q04721
TCKEGWQGLDCTLPC

MEGF11

466

A6BM72
CTLPCPSGTWGLNCN

MEGF11

476

A6BM72
PCLVGNCAWCEDGVF

KRT40

71

Q6A162
CVANWPDLLSQCGCG

MKKS

486

Q9NPJ1
PWGLLLCLLCSSCLG

LOXL3

11

P58215
AACWLPYGCACLAPA

GPR62

251

Q9BZJ7
LCVLPTWICDGSNDC

LRP1B

2651

Q9NZR2
LGCCFVCAWALGGPR

GPR179

16

Q6PRD1
CANELAAADGLPCWN

GPC5

406

P78333
LEGTPSLQSCWAACC

KIAA0319L

76

Q8IZA0
CCQLWLLSLRQGCGA

KCNK16

261

Q96T55
GNLLCPSCWDFCELC

LMLN

591

Q96KR4
CATGEIDCIPGAWRC

LRP5

1266

O75197
CAPGPLCWGALAAQL

GP1BB

141

P13224
SLLGLWLLLCSCGCP

PCYOX1

11

Q9UHG3
WLLLCSCGCPEGAEL

PCYOX1

16

Q9UHG3
CGLCLKADPRFECGW

PLXNA1

816

Q9UIW2
CWAQRPSCGLCLKAD

PLXNA3

786

P51805
CLKADPRFNCGWCIS

PLXNA3

796

P51805
CGLCLKADPDFACGW

PLXNA4

811

Q9HCM2
ASCLQAQDPLCGWCV

PLXNB3

481

Q9ULL4
AQDPLCGWCVLQGRC

PLXNB3

486

Q9ULL4
GCPWLVIADFGCCLA

PINK1

376

Q9BXM7
CEDCLLIGPQCAWCA

ITGB6

31

P18564
SCLPGWAGLHCNESC

PEAR1

381

Q5VY43
GITCCCSLIPSGAEW

IL27RA

281

Q6UWB1
GCLADQGCGWCLTSA

MEGF8

856

Q7Z7M0
WTAECCLCNLRGGAL

KDM4C

751

Q9H3R0
CRCLEGEVDCWPLTC

NELL1

716

Q92832
GEVDCWPLTCPNLSC

NELL1

721

Q92832
GCRCLELDCWDGPNQ

PLCD1

336

P51178
PLQCHGSTGFCWCVD

NID2

971

Q14112
QCGAGTCCAISLWLR

PROK1

31

P58294
PAAAFCGWLSCAGCC

PAQR8

181

Q8TEZ7
ARCLALGPECGWCVQ

ITGB8

56

P26012
CIESGPGCTWCQKLN

ITGB2

36

P05107
WCQCGSCLPSQLPES

P2RX7

476

Q99572
WCPLQGCRHLLACGT

DPH7

21

Q9BTV6
SADRCVPLNNGCGCW

FCGBP

1996

Q9Y6R7
LDCHCECNSGWLEPL

GALNT4

226

Q8N4A0
LRTCGQCLEQPGCGW

ATRNL1

946

Q5VV63
PGLGSNCCVPLLCWA

GOLGA8H

611

P0CJ92
CRCGPGWLGSQCECS

ITGB3

486

P05106
DPYCGLGFALWCLCS

DIP2A

1196

Q14689
CATLGAAWGSPCERC

FBN2

921

P35556
CCCSLGKAWGNPCET

FBN2

1606

P35556
WCCGICEEAPLGRAY

nan

6

Q1T7F1
CAWGAAVALGTLCLC

PRRT3

606

Q5FWE3
LLPWACCCLCGSALA

COL26A1

6

Q96A83
WCPGANICLPLDASC

PKD1

646

P98161
DCPEGWTGLICNETC

MEGF6

541

O75095
GRWGLGCQEICPACQ

MEGF6

776

O75095
GDGTLCFVLLLCCWQ

SPACA7

6

Q96KW9
CECPRGLFWNGTLCV

SSPOP

506

A2VEC9
SCVAGCNCPLGLLWD

SSPOP

856

A2VEC9
CNCPLGLLWDPEGQC

SSPOP

861

A2VEC9
PSPTAACHLCLCWEG

KCP

741

Q6ZWJ8
PLGATGLAQCAELCW

SCP2

356

P22307
FHCLCLQGWTGPLCN

NOTCH4

866

Q99466
VGGCLLCCGAWVCTG

CLDN5

176

O00501
LCCGAWVCTGRPDLS

CLDN5

181

O00501
LGCLAVGIWGLVCCC

VSIG8

276

P0DPA2
CGGCLSCLLIPLALW

TM4SF18

6

Q96CE8
WVCCLCLGPAHGDSQ

PTGIR

306

P43119
FSGIPCEGGLRCLCW

TBC1D13

31

Q9NVG8
ASWVPCLCSGASCLL

SERINC3

11

Q13530
LEGQCPCCEKSLLWG

SLX1A

231

Q9BQ83
AWRLGASACPALCTC

SLIT1

26

O75093
TCWGCGSVACTLCGL

SIVA1

141

O15304
CLWPRSGICGCEFGL

TRPV5

611

Q9NQA5