Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunction1-phosphatidylinositol-5-phosphate 4-kinase activity

PIP4K2A PIP4K2B PIP4K2C

1.39e-083493GO:0016309
GeneOntologyMolecularFunction1-phosphatidylinositol-4-phosphate 5-kinase activity

PIP4K2A PIP4K2B PIP4K2C

1.15e-069493GO:0016308
GeneOntologyMolecularFunctionphosphatidylinositol kinase activity

PIP4K2A PIP4K2B PIP4K2C

3.47e-0526493GO:0052742
GeneOntologyMolecularFunctionlipid kinase activity

PIP4K2A PIP4K2B PIP4K2C

1.39e-0441493GO:0001727
GeneOntologyMolecularFunctionphosphorylation-dependent protein binding

PTPN6 ANK2

2.62e-0410492GO:0140031
GeneOntologyMolecularFunctionDNA-binding transcription factor activity, RNA polymerase II-specific

CREBRF ZNF732 FEZF1 ZNF43 ZNF92 ZNF74 ZNF208 ZNF236 MGA ZNF730

1.96e-0314124910GO:0000981
GeneOntologyMolecularFunctiontransition metal ion binding

ZNF385D FLG ZNF346 CYP8B1 ZNF92 ZNF208 ZNF385B F8 ZMAT1

2.16e-031189499GO:0046914
GeneOntologyMolecularFunctionRNA polymerase II transcription regulatory region sequence-specific DNA binding

CREBRF ZNF732 FEZF1 ZNF43 ZNF92 ZNF74 ZNF208 ZNF236 MGA ZNF730

2.50e-0314594910GO:0000977
GeneOntologyMolecularFunctionRNA polymerase II cis-regulatory region sequence-specific DNA binding

ZNF732 FEZF1 ZNF43 ZNF92 ZNF74 ZNF208 ZNF236 MGA ZNF730

2.94e-031244499GO:0000978
GeneOntologyBiologicalProcess1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process

PIP4K2A PIP4K2B PIP4K2C

1.11e-083473GO:1902635
GeneOntologyBiologicalProcess1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate metabolic process

PIP4K2A PIP4K2B PIP4K2C

4.43e-084473GO:1902633
GeneOntologyBiologicalProcesspositive regulation of autophagosome assembly

PIP4K2A PIP4K2B PIP4K2C

1.23e-0520473GO:2000786
GeneOntologyBiologicalProcesspositive regulation of vacuole organization

PIP4K2A PIP4K2B PIP4K2C

2.46e-0525473GO:0044090
GeneOntologyBiologicalProcessregulation of autophagosome assembly

PIP4K2A PIP4K2B PIP4K2C

2.02e-0450473GO:2000785
GeneOntologyBiologicalProcessphosphatidylinositol biosynthetic process

BMX PIP4K2A PIP4K2B PIP4K2C

2.31e-04132474GO:0006661
GeneOntologyBiologicalProcessnegative regulation of insulin receptor signaling pathway

PIP4K2A PIP4K2B PIP4K2C

2.54e-0454473GO:0046627
GeneOntologyBiologicalProcessnegative regulation of cellular response to insulin stimulus

PIP4K2A PIP4K2B PIP4K2C

3.30e-0459473GO:1900077
GeneOntologyBiologicalProcessautophagosome-lysosome fusion

PIP4K2A PIP4K2B

3.31e-0412472GO:0061909
GeneOntologyBiologicalProcessregulation of vacuole organization

PIP4K2A PIP4K2B PIP4K2C

3.64e-0461473GO:0044088
GeneOntologyBiologicalProcessphosphatidylinositol phosphate biosynthetic process

PIP4K2A PIP4K2B PIP4K2C

4.59e-0466473GO:0046854
DomainPInositol-4-P-5-kinase

PIP4K2A PIP4K2B PIP4K2C

5.90e-077493IPR023610
DomainZnf_C2H2-like

ZNF385D ZNF346 ZNF732 FEZF1 ZNF43 ZNF92 ZNF74 ZNF208 ZNF385B ZNF236 ZMAT1 ZNF730

7.12e-077964912IPR015880
DomainZnf_C2H2

ZNF385D ZNF346 ZNF732 FEZF1 ZNF43 ZNF92 ZNF74 ZNF208 ZNF385B ZNF236 ZMAT1 ZNF730

8.02e-078054912IPR007087
DomainZnF_C2H2

ZNF385D ZNF346 ZNF732 FEZF1 ZNF43 ZNF92 ZNF74 ZNF208 ZNF385B ZNF236 ZMAT1 ZNF730

8.34e-078084912SM00355
DomainPIPK

PIP4K2A PIP4K2B PIP4K2C

9.42e-078493PS51455
DomainPIPKc

PIP4K2A PIP4K2B PIP4K2C

9.42e-078493SM00330
Domain-

PIP4K2A PIP4K2B PIP4K2C

9.42e-0784933.30.800.10
DomainPInositol-4-P-5-kinase_N

PIP4K2A PIP4K2B PIP4K2C

9.42e-078493IPR027484
DomainPInositol-4-P-5-kinase_C

PIP4K2A PIP4K2B PIP4K2C

9.42e-078493IPR027483
Domain-

PIP4K2A PIP4K2B PIP4K2C

9.42e-0784933.30.810.10
DomainPInositol-4-P-5-kinase_core

PIP4K2A PIP4K2B PIP4K2C

9.42e-078493IPR002498
DomainPIP5K

PIP4K2A PIP4K2B PIP4K2C

9.42e-078493PF01504
DomainZnF_U1

ZNF385D ZNF346 ZNF385B ZMAT1

9.46e-0729494SM00451
DomainZnf_U1

ZNF385D ZNF346 ZNF385B ZMAT1

9.46e-0729494IPR003604
DomainZnf_C2H2_matrin

ZNF385D ZNF346 ZNF385B

3.67e-0612493IPR000690
DomainRIBOSOMAL_L44E

RPL36AL RPL36A

6.74e-062492PS01172
DomainRibosomal_L44e

RPL36AL RPL36A

6.74e-062492IPR000552
DomainRibosomal_L44

RPL36AL RPL36A

6.74e-062492PF00935
Domain-

RPL36AL RPL36A

6.74e-0624923.10.450.80
DomainRibosomal_L44e

RPL36AL RPL36A

6.74e-062492PD002841
DomainZF_MATRIN

ZNF385D ZNF346 ZNF385B

1.35e-0518493PS50171
Domainzf-C2H2_6

ZNF732 FEZF1 ZNF43 ZNF92 ZNF208 ZNF236 ZNF730

1.66e-05314497PF13912
DomainRibosomal_zn-bd

RPL36AL RPL36A

2.40e-049492IPR011332
DomainKRAB

ZNF732 ZNF43 ZNF92 ZNF74 ZNF208 ZNF730

3.32e-04358496PS50805
DomainKRAB

ZNF732 ZNF43 ZNF92 ZNF74 ZNF208 ZNF730

3.32e-04358496PF01352
Domain-

ZNF732 FEZF1 ZNF43 ZNF92 ZNF74 ZNF208 ZNF236 ZNF730

3.53e-046794983.30.160.60
DomainKRAB

ZNF732 ZNF43 ZNF92 ZNF74 ZNF208 ZNF730

3.90e-04369496SM00349
DomainKRAB

ZNF732 ZNF43 ZNF92 ZNF74 ZNF208 ZNF730

3.95e-04370496IPR001909
Domainzf-C2H2

ZNF732 FEZF1 ZNF43 ZNF92 ZNF74 ZNF208 ZNF236 ZNF730

4.05e-04693498PF00096
DomainZnf_C2H2/integrase_DNA-bd

ZNF732 FEZF1 ZNF43 ZNF92 ZNF74 ZNF208 ZNF236 ZNF730

4.09e-04694498IPR013087
DomainZINC_FINGER_C2H2_2

ZNF732 FEZF1 ZNF43 ZNF92 ZNF74 ZNF208 ZNF236 ZNF730

8.45e-04775498PS50157
DomainZINC_FINGER_C2H2_1

ZNF732 FEZF1 ZNF43 ZNF92 ZNF74 ZNF208 ZNF236 ZNF730

8.59e-04777498PS00028
Domainzf-C2H2_jaz

ZNF385D ZNF385B

1.51e-0322492PF12171
DomainBRCT

SLF1 RFC1

1.51e-0322492SM00292
DomainZnf_C2H2_jaz

ZNF385D ZNF385B

1.51e-0322492IPR022755
Domain-

SLF1 RFC1

1.65e-03234923.40.50.10190
DomainBRCT

SLF1 RFC1

2.11e-0326492PS50172
DomainBRCT_dom

SLF1 RFC1

2.44e-0328492IPR001357
PathwayREACTOME_PI5P_REGULATES_TP53_ACETYLATION

PIP4K2A PIP4K2B PIP4K2C

1.76e-069403M27655
PathwayREACTOME_PI5P_REGULATES_TP53_ACETYLATION

PIP4K2A PIP4K2B PIP4K2C

1.76e-069403MM15357
PathwayREACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE

BMX PIP4K2A PIP4K2B PIP4K2C

1.16e-0550404MM14641
PathwayREACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE

BMX PIP4K2A PIP4K2B PIP4K2C

1.47e-0553404M662
PathwayREACTOME_RNA_POLYMERASE_II_TRANSCRIPTION

CCNT2 ZNF732 ZNF43 ZNF92 PIP4K2A ZNF74 PIP4K2B ZNF208 PIP4K2C THOC2 MGA ZNF730 NLRC4 RPAP2

1.48e-0513874014M734
PathwayREACTOME_PI_METABOLISM

BMX PIP4K2A PIP4K2B PIP4K2C

6.48e-0577404MM14590
PathwayREACTOME_REGULATION_OF_TP53_ACTIVITY_THROUGH_ACETYLATION

PIP4K2A PIP4K2B PIP4K2C

7.35e-0529403MM15340
PathwayREACTOME_INFLUENZA_INFECTION

RPL36AL RPL36A NUP107 CANX RPS23

7.72e-05157405M4669
PathwayREACTOME_REGULATION_OF_TP53_ACTIVITY_THROUGH_ACETYLATION

PIP4K2A PIP4K2B PIP4K2C

8.15e-0530403M27637
PathwayREACTOME_PI_METABOLISM

BMX PIP4K2A PIP4K2B PIP4K2C

9.10e-0584404M676
PathwayWP_PHOSPHATIDYL_INOSITOL_PHOSPHATE_PATHWAY

PIP4K2A PIP4K2B PIP4K2C

2.95e-0446403M48317
PathwayWP_PHOSPHOINOSITIDES_METABOLISM

PIP4K2A PIP4K2B PIP4K2C

3.56e-0449403M40046
PathwayREACTOME_GENE_EXPRESSION_TRANSCRIPTION

CCNT2 NUP107 ZNF43 PIP4K2A PIP4K2B ZNF208 PIP4K2C THOC2 MGA RPAP2

4.38e-0410224010MM15436
PathwayKEGG_INOSITOL_PHOSPHATE_METABOLISM

PIP4K2A PIP4K2B PIP4K2C

4.75e-0454403M3896
PathwayREACTOME_PLATELET_SENSITIZATION_BY_LDL

PTPN6 APOB

1.04e-0317402MM15096
PathwayREACTOME_PLATELET_SENSITIZATION_BY_LDL

PTPN6 APOB

1.04e-0317402M919
Pubmed

Functional analysis of the biochemical activity of mammalian phosphatidylinositol 5 phosphate 4-kinase enzymes.

PIP4K2A PIP4K2B PIP4K2C

2.63e-09349330718367
Pubmed

Evolutionarily conserved structural changes in phosphatidylinositol 5-phosphate 4-kinase (PI5P4K) isoforms are responsible for differences in enzyme activity and localization.

PIP4K2A PIP4K2B PIP4K2C

2.63e-09349323758345
Pubmed

The function of phosphatidylinositol 5-phosphate 4-kinase γ (PI5P4Kγ) explored using a specific inhibitor that targets the PI5P-binding site.

PIP4K2A PIP4K2B PIP4K2C

2.63e-09349325495341
Pubmed

The Lipid Kinase PI5P4Kβ Is an Intracellular GTP Sensor for Metabolism and Tumorigenesis.

PIP4K2A PIP4K2B PIP4K2C

2.63e-09349326774281
Pubmed

A new pathway for synthesis of phosphatidylinositol-4,5-bisphosphate.

PIP4K2A PIP4K2B PIP4K2C

1.05e-0844939367159
Pubmed

PIP4Ks Suppress Insulin Signaling through a Catalytic-Independent Mechanism.

PIP4K2A PIP4K2B PIP4K2C

1.05e-08449331091439
Pubmed

Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.

CCNT2 RPL36AL NUP107 CANX PKP2 MCM5 PPIL2 RPS23 RFC1 TOPORS THOC2 MGA RPAP2

1.20e-081247491327684187
Pubmed

Localization of mRNAs for phosphatidylinositol phosphate kinases in the mouse brain during development.

PIP4K2A PIP4K2B PIP4K2C

9.16e-08749315018809
Pubmed

Btk-dependent regulation of phosphoinositide synthesis.

PIP4K2A PIP4K2B PIP4K2C

1.46e-07849315046600
Pubmed

Targeted and Interactome Proteomics Revealed the Role of PHD2 in Regulating BRD4 Proline Hydroxylation.

RPL36A PIP4K2A PIP4K2B MCM5 RPS23 PIP4K2C RFC1 MGA

1.79e-0744149831239290
Pubmed

PI(5)P regulates autophagosome biogenesis.

PIP4K2A PIP4K2B PIP4K2C

3.13e-071049325578879
Pubmed

UBE2O promotes lipid metabolic reprogramming and liver cancer progression by mediating HADHA ubiquitination.

ZNF346 RPL36AL MCM5 PPIL2 APOB RPS23 PIP4K2C THOC2

4.05e-0749149836273042
Pubmed

The deubiquitinase USP7 stabilizes Maf proteins to promote myeloma cell survival.

RPL36AL RPL36A PIP4K2A PIP4K2B PIP4K2C RFC1

6.67e-0722049631822558
Pubmed

Clustered organization of homologous KRAB zinc-finger genes with enhanced expression in human T lymphoid cells.

ZNF43 ZNF92 ZNF208

1.45e-06164938467795
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

NUP107 ZNF92 CANX PIP4K2A PPIL2 PIP4K2C TOPORS RPAP2

1.56e-0658849838580884
Pubmed

Proteasome-mediated degradation of apolipoprotein B targets both nascent peptides cotranslationally before translocation and full-length apolipoprotein B after translocation into the endoplasmic reticulum.

CANX APOB

1.94e-0624929765244
Pubmed

Phosphatidylinositol-5-Phosphate 4-Kinases Regulate Cellular Lipid Metabolism By Facilitating Autophagy.

PIP4K2A PIP4K2B

1.94e-06249229727621
Pubmed

PIP4K2A and PIP4K2C transcript levels are associated with cytogenetic risk and survival outcomes in acute myeloid leukemia.

PIP4K2A PIP4K2C

1.94e-06249231109595
Pubmed

A role for palmitoylation in the quality control, assembly and secretion of apolipoprotein B.

CANX APOB

1.94e-06249214498830
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

CREBRF FLG RPL36AL RPL36A ANK2 PIP4K2A PIP4K2B MCM5 APOB RPS23 NEB

4.08e-061442491135575683
Pubmed

Depletion of a putatively druggable class of phosphatidylinositol kinases inhibits growth of p53-null tumors.

PIP4K2A PIP4K2B

5.83e-06349224209622
Pubmed

Characterisation of an mRNA encoding a human ribosomal protein homologous to the yeast L44 ribosomal protein.

RPL36AL RPL36A

5.83e-0634923542712
Pubmed

Pharmacological inhibition of PI5P4Kα/β disrupts cell energy metabolism and selectively kills p53-null tumor cells.

PIP4K2A PIP4K2B

5.83e-06349234001596
Pubmed

TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.

RPL36AL RPL36A CANX PKP2 MCM5 PPIL2 APOB RPS23 THOC2

6.23e-0694949936574265
Pubmed

Global mapping of herpesvirus-host protein complexes reveals a transcription strategy for late genes.

RANBP10 ZNF346 CANX PIP4K2A PIP4K2B PIP4K2C RPAP2

9.39e-0653349725544563
Pubmed

Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.

CCNT2 RANBP10 RPL36A PIP4K2C RFC1 THOC2 MGA

9.39e-0653349730554943
Pubmed

Upregulation of TIPE1 in tubular epithelial cell aggravates diabetic nephropathy by disrupting PHB2 mediated mitophagy.

CANX PIP4K2B PIP4K2C

1.04e-053049335152003
Pubmed

PI5P4Ks drive metabolic homeostasis through peroxisome-mitochondria interplay.

PIP4K2A PIP4K2B

1.16e-05449233984270
Pubmed

Differential interaction of coagulation factor VIII and factor V with protein chaperones calnexin and calreticulin.

CANX F8

1.16e-0544929525969
Pubmed

BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.

RPL36AL RPL36A CANX PIP4K2A PIP4K2B MCM5 RPS23 PIP4K2C RFC1 THOC2

1.26e-051318491030463901
Pubmed

Distribution and localization of phosphatidylinositol 5-phosphate, 4-kinase alpha and beta in the brain.

PIP4K2A PIP4K2B

1.94e-05549232449185
Pubmed

Two-Dimensional Fractionation Method for Proteome-Wide Cross-Linking Mass Spectrometry Analysis.

RPL36AL RPL36A CANX PIP4K2A MCM5 RPS23 PIP4K2C THOC2

2.23e-0584749835235311
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

NUP107 ZNF43 PIP4K2A PKP2 PIP4K2B PIP4K2C TOPORS MGA RPAP2

2.26e-05111649931753913
Pubmed

Branches of the B cell antigen receptor pathway are directed by protein conduits Bam32 and Carma1.

PIP4K2A PIP4K2B

2.91e-05649214614850
Pubmed

Tissue-Specific Regulation of the Wnt/β-Catenin Pathway by PAGE4 Inhibition of Tankyrase.

RPL36A CANX MCM5 RPS23 MGA

3.04e-0525649532698014
Pubmed

Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS.

CCNT2 PIP4K2A PIP4K2B RPS23 PIP4K2C NEB

3.16e-0543249623455922
Pubmed

Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.

PIP4K2A PIP4K2B PPIL2 PIP4K2C RFC1 THOC2 RPAP2

3.19e-0564549725281560
Pubmed

Intracellular lipidation of newly synthesized apolipoprotein A-I in primary murine hepatocytes.

CANX APOB

4.07e-05749216204232
Pubmed

PIKES Analysis Reveals Response to Degraders and Key Regulatory Mechanisms of the CRL4 Network.

PIP4K2A PIP4K2B PIP4K2C

4.63e-054949331973889
Pubmed

Phosphatidylinositol-4-phosphate 5-kinases and phosphatidylinositol 4,5-bisphosphate synthesis in the brain.

PIP4K2A PIP4K2B

5.42e-05849220622009
Pubmed

The evolutionarily conserved Krüppel-associated box domain defines a subfamily of eukaryotic multifingered proteins.

ZNF43 ZNF92

5.42e-0584922023909
Pubmed

RNA-binding proteins with basic-acidic dipeptide (BAD) domains self-assemble and aggregate in Alzheimer's disease.

CCNT2 RPL36AL RPL36A PKP2 RPS23 RFC1 THOC2

6.01e-0571349729802200
Pubmed

EDEM1 Drives Misfolded Protein Degradation via ERAD and Exploits ER-Phagy as Back-Up Mechanism When ERAD Is Impaired.

CANX PIP4K2A PIP4K2B PIP4K2C

6.06e-0515049432423001
Pubmed

Analysis of Ku70 S155 Phospho-Specific BioID2 Interactome Identifies Ku Association with TRIP12 in Response to DNA Damage.

RPL36A CANX RFC1 MGA

7.05e-0515649437108203
Pubmed

New interaction partners for Nek4.1 and Nek4.2 isoforms: from the DNA damage response to RNA splicing.

RPL36A CANX MCM5 APOB RPS23 NEB

8.17e-0551349625798074
Pubmed

Functional analysis of the SRY-KRAB interaction in mouse sex determination.

ZNF43 ZNF208

8.69e-051049218588511
Pubmed

Sry associates with the heterochromatin protein 1 complex by interacting with a KRAB domain protein.

ZNF43 ZNF208

1.06e-041149215469996
Pubmed

MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.

FLG CCNT2 RPL36AL RPL36A CANX PPIL2 RPS23 THOC2

1.24e-04108249838697112
Pubmed

Epigenetic gene silencing by the SRY protein is mediated by a KRAB-O protein that recruits the KAP1 co-repressor machinery.

ZNF43 ZNF208

1.50e-041349219850934
Pubmed

Human transcription factor protein interaction networks.

FLG RPL36AL SLF1 RPL36A NUP107 CANX PPIL2 RFC1 MGA

1.51e-04142949935140242
Pubmed

Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.

RANBP10 RPL36AL RPL36A CANX PIP4K2A PIP4K2B MCM5 RPS23 PIP4K2C

1.70e-04145149930550785
Pubmed

The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation.

CCNT2 ZNF346 RPL36AL SLF1 RPL36A CANX MCM5 RPS23

1.92e-04115349829845934
Pubmed

FBW7 suppresses ovarian cancer development by targeting the N6-methyladenosine binding protein YTHDF2.

FLG ZNF346 NUP107 CANX RPS23 RFC1

1.93e-0460149633658012
Pubmed

Structure and evolution of mammalian ribosomal proteins.

RPL36AL RPL36A RPS23

2.00e-04804938722009
Pubmed

Detailed characterization of the mouse embryonic stem cell transcriptome reveals novel genes and intergenic splicing associated with pluripotency.

RPL36AL RPL36A

2.02e-041549218400104
Pubmed

Expansion and diversification of KRAB zinc-finger genes within a cluster including Regulator of sex-limitation 1 and 2.

ZNF43 ZNF208

2.02e-041549215885501
Pubmed

WWP2 ubiquitylates RNA polymerase II for DNA-PK-dependent transcription arrest and repair at DNA breaks.

RPL36AL RPL36A PKP2 RPS23 RFC1 RPAP2

2.19e-0461549631048545
Pubmed

Intestinal SURF4 is essential for apolipoprotein transport and lipoprotein secretion.

CANX APOB

2.30e-041649238042368
Pubmed

Molecular Characterization of the Oncogene BTF3 and Its Targets in Colorectal Cancer.

RPL36AL RPL36A CANX PKP2 RPS23 RFC1

2.41e-0462649633644029
Pubmed

The C-terminal cytoplasmic tail of hedgehog receptor Patched1 is a platform for E3 ubiquitin ligase complexes.

PIP4K2A PIP4K2B PIP4K2C

2.48e-048649326885983
Pubmed

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.

CCNT2 RPL36AL RPL36A CANX PIP4K2A PIP4K2B PIP4K2C

2.71e-0491049736736316
Pubmed

A conserved acetylation switch enables pharmacological control of tubby-like protein stability.

RANBP10 PIP4K2A PIP4K2B PIP4K2C

2.78e-0422349433187986
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

NUP107 CANX MCM5 RPS23 RFC1 THOC2

3.01e-0465349622586326
Pubmed

C9orf72 protein quality control by UBR5-mediated heterotypic ubiquitin chains.

RPL36AL RPL36A NUP107 CANX MCM5 RPS23 RFC1 THOC2

3.44e-04125749837317656
Pubmed

Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.

NUP107 PKP2 MCM5 RPS23 RPAP2

3.82e-0444049534244565
Pubmed

Nuclear lamina genetic variants, including a truncated LAP2, in twins and siblings with nonalcoholic fatty liver disease.

CANX MCM5 APOB RPS23

3.91e-0424449428902428
Pubmed

Structural snapshots of actively translating human ribosomes.

RPL36A RPS23

4.01e-042149225957688
Pubmed

MYC multimers shield stalled replication forks from RNA polymerase.

RPL36A CANX MCM5 PPIL2 RPS23 RFC1 THOC2

4.46e-0498949736424410
Pubmed

Cell cycle-dependent phosphorylation regulates RECQL4 pathway choice and ubiquitination in DNA double-strand break repair.

RANBP10 ZNF346 RPL36A CANX MCM5 RPS23 RFC1 RPAP2

5.13e-04133549829229926
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

NUP107 PIP4K2A PKP2 MCM5 RPS23 PIP4K2C RFC1 MGA

5.60e-04135349829467282
Pubmed

Unbiased Identification of trans Regulators of ADAR and A-to-I RNA Editing.

ZNF346 ANK2 RFC1 THOC2

5.80e-0427149432433965
Pubmed

TNIP1 inhibits selective autophagy via bipartite interaction with LC3/GABARAP and TAX1BP1.

FLG PPIL2 PIP4K2C

6.11e-0411749336898370
Pubmed

Impaired plasma membrane localization of ubiquitin ligase complex underlies 3-M syndrome development.

BMX RPL36AL CANX APOB RFC1

6.58e-0449649531343991
Pubmed

In Vitro Identification of Histatin 5 Salivary Complexes.

FLG F8

6.67e-042749226544073
Pubmed

TRAIP regulates replication fork recovery and progression via PCNA.

MCM5 RFC1

6.67e-042749227462463
Pubmed

Mapping the Ku Interactome Using Proximity-Dependent Biotin Identification in Human Cells.

PPIL2 RFC1 THOC2 MGA

6.82e-0428349430585729
Pubmed

Comprehensive Proteomic Analysis of PGC7-Interacting Proteins.

ZNF346 NUP107 CANX PKP2

7.18e-0428749428712289
Pubmed

Mitochondrial Raf1 Regulates Glutamine Catabolism.

RANBP10 ANK2 CANX PKP2

7.28e-0428849438496616
Pubmed

Regulator of sex-limitation (Rsl) encodes a pair of KRAB zinc-finger genes that control sexually dimorphic liver gene expression.

ZNF43 ZNF208

7.71e-042949214563677
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

RPL36A NUP107 CANX MCM5 APOB RPS23 RFC1 THOC2

7.86e-04142549830948266
Pubmed

NOTCH1 nuclear interactome reveals key regulators of its transcriptional activity and oncogenic function.

RANBP10 MCM5 RFC1

8.11e-0412949323022380
Pubmed

High-density SNP association study and copy number variation analysis of the AUTS1 and AUTS5 loci implicate the IMMP2L-DOCK4 gene region in autism susceptibility.

FEZF1 ZNF385B

8.25e-043049219401682
Pubmed

Wnt regulation: exploring Axin-Disheveled interactions and defining mechanisms by which the SCF E3 ubiquitin ligase is recruited to the destruction complex.

RPL36A CANX MCM5 RPS23 RFC1 THOC2

9.28e-0480949632129710
Pubmed

Expression of genes involved in mammalian meiosis during the transition from egg to embryo.

PTPN6 MCM5

9.98e-043349211389549
Pubmed

TNRC6 proteins modulate hepatitis C virus replication by spatially regulating the binding of miR-122/Ago2 complexes to viral RNA.

RPL36AL RPL36A RPS23 RFC1

1.04e-0331749430997501
Pubmed

Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.

RPL36AL RPL36A NUP107 RPS23 RFC1 THOC2

1.17e-0384749635850772
Pubmed

Characterization of the Cardiac Overexpression of HSPB2 Reveals Mitochondrial and Myogenic Roles Supported by a Cardiac HspB2 Interactome.

RPL36AL RPL36A PKP2

1.18e-0314749326465331
Pubmed

A systems wide mass spectrometric based linear motif screen to identify dominant in-vivo interacting proteins for the ubiquitin ligase MDM2.

CANX RPS23

1.25e-033749224583282
Pubmed

Large-scale identification of mammalian proteins localized to nuclear sub-compartments.

ZNF346 RFC1

1.32e-033849211555636
Pubmed

The Tumor Suppressor CIC Directly Regulates MAPK Pathway Genes via Histone Deacetylation.

NUP107 RPS23 RFC1 THOC2 MGA

1.35e-0358349529844126
Pubmed

The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.

CCNT2 NUP107 CANX RPS23 TOPORS THOC2 MGA

1.41e-03120349729180619
InteractionKLHL40 interactions

ZNF92 PKP2 NEB MGA

1.17e-0559484int:KLHL40
InteractionUBE2O interactions

ZNF346 RPL36AL ZNF92 PIP4K2A MCM5 PPIL2 APOB RPS23 PIP4K2C THOC2

1.37e-057904810int:UBE2O
InteractionMAFB interactions

RPL36AL RPL36A PIP4K2A PIP4K2B PIP4K2C RFC1

2.49e-05246486int:MAFB
InteractionPRICKLE3 interactions

RANBP10 PIP4K2A PIP4K2B PIP4K2C

2.88e-0574484int:PRICKLE3
InteractionZNF428 interactions

PIP4K2A PIP4K2B PIP4K2C

4.92e-0530483int:ZNF428
CytobandEnsembl 112 genes in cytogenetic band chr19p12

ZNF43 ZNF208 ZNF730

3.09e-04122493chr19p12
CytobandEnsembl 112 genes in cytogenetic band chr5q35

CREBRF ZNF346 CANX

2.05e-03235493chr5q35
Cytoband19p12

ZNF208 ZNF730

4.21e-039049219p12
Cytoband22q11.21

ZNF74 PPIL2

6.33e-0311149222q11.21
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZNF732 FEZF1 ZNF43 ZNF92 ZNF74 ZNF208 ZNF236 ZNF730

3.42e-0571833828
GeneFamilyL ribosomal proteins

RPL36AL RPL36A

3.90e-0351332729
GeneFamilyAnkyrin repeat domain containing

ANKRD31 SLF1 ANK2

9.61e-03242333403
GeneFamilySH2 domain containing

PTPN6 BMX

1.46e-02101332741
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF732 WNT9A MCM5 ZNF730

3.57e-05169494121768fc51fc3441ec725346a1bbe29e21d05971
ToppCellILEUM-inflamed-(5)_Plasma-(5)_IgM_plasma_cells|(5)_Plasma / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

PTPN6 RPL36AL CANX RPS23

5.07e-0518549426ea60b6392410fab048f2e406a9860a018429cc
ToppCellmetastatic_Lymph_Node-Endothelial_cells-Tumor_ECs|metastatic_Lymph_Node / Location, Cell class and cell subclass

ZNF385D BMX ZNF208 TPD52L1

5.29e-051874942713f526f86911fbbf6c7a3e69230f2e6bde31c3
ToppCelldroplet-Lung-30m-Hematologic|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PTPN6 RPL36AL RPL36A RPS23

5.40e-05188494614b6b83b54bceaf213698310cbb97139bf8dce2
ToppCellPND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SLF1 ANK2 MCM5 RFC1

5.98e-05193494f25bdd10ef531b8d8441ea84573078b4b1b0f105
ToppCellNS-moderate-d_07-13-Epithelial-Basal|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ZNF385D RPS23 TPD52L1

6.05e-0569493c2d7333a9d7c7e1cdc36d28192ddb6afa2013816
ToppCellPBMC|World / Location, Disease Group, Cell group, Cell class (2021.03.09)

RPL36AL RPL36A PIP4K2A RPS23

6.22e-05195494211eba45a502b961873ca2d4642f7852e6e89d7a
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(3)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

SLF1 ZNF732 MCM5 ZNF730

6.22e-0519549456d8734d020b3da08a5aa9e67999706a9e023a99
ToppCellPBMC|World / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

RPL36AL RPL36A PIP4K2A RPS23

6.22e-051954948cd7667a65d77dd7b301090a9b65aba254741375
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(3)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

SLF1 ZNF732 MCM5 ZNF730

6.35e-05196494df366d76ea55f49e349d622effa57c1535df8400
ToppCellMild/Remission|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

CREBRF RPL36A ZNF92 RPS23

6.35e-0519649471603a3b7df40eb3f267345f55e44a812fea7926
ToppCellBL-critical-LOC-Lymphoid|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

RPL36A PIP4K2A RPS23 RFC1

6.60e-051984941c0227e58a64c0bf509bfb9578fb91277316b120
ToppCellPBMC_fresh-frozen|World / Compartment, severity and other cell annotations on 10x 3' data (130k)

RPL36AL RPL36A PIP4K2A RPS23

6.60e-05198494dcc223a0396b8b673e4ed8c6733ec6cd74e9a03a
ToppCell367C-Endothelial_cells-Endothelial-A_(Artery)-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

ZNF385D RPL36AL RPL36A TPD52L1

6.73e-0519949462936fb64b33f7ad671f9c610bed665f17d3145e
ToppCellParenchymal|World / Cell types per location group and 10X technology with lineage, and cell group designations

RPL36AL RPL36A ZNF385B RPS23

6.73e-05199494cce684df78421b814083aed16c4cbbac5f287bbc
ToppCell367C-Endothelial_cells-Endothelial-A_(Artery)|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

ZNF385D RPL36AL RPL36A TPD52L1

6.73e-05199494f53e0e4c34e6aec81ab07593aa11e045ba04df06
ToppCellMegakaryocytic-erythropoietic-Megakaryo-cells-Megakaryocyte|Megakaryo-cells / Lineage, cell class and subclass

RPL36AL RPL36A CANX RPS23

6.86e-05200494f36023bb369d17b8ec8724616737738e3df01987
ToppCellParenchymal-NucSeq-Stromal-Schwann|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ANK2 MCM5 PIP4K2C

4.21e-041334938819fd897b97812355e1709fcc42754522d5fb27
ToppCellParenchymal-NucSeq-Stromal-Schwann-Schwann_nonmyelinating|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ANK2 MCM5 PIP4K2C

4.21e-04133493b4e68a9a223e5188f1a00c7dc9bb2d675cde1d40
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Lymphocytic-T_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPN6 RPL36AL RPS23

5.10e-0414249358c2882cb0ede8cc5d84c85a650d28267268e748
ToppCellICU-SEP-Lymphocyte-T_NK-Treg|ICU-SEP / Disease, Lineage and Cell Type

ANKRD31 FSIP2 MCM5

5.42e-04145493ee99b58462f955b96d036aa67e343db047d66f64
ToppCellASK454-Immune|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq

PTPN6 RPL36AL RPS23

5.75e-041484931076c69bf2a5e4557aa35643fd9bd86e8610815b
ToppCellTCGA-Bone_and_Soft_Tissue-Primary_Tumor-Sarcoma-Poorly_Differentiated_or_Epithelioid_Leiomyosarcoma|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

CHRDL2 ZNF385B TPD52L1

6.21e-041524936f9c343669883618cd9c1c8921a90c34d153f303
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_ALM_Tnc|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

WNT9A NEB TPD52L1

6.46e-041544930066b2b8cfc74603e97f271ef5efc7ec512110dc
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_artery-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

BMX ZNF732 F8

6.83e-04157493275a4c6fef1fff8da2bdc48e3924ad05c5e5cfc8
ToppCellLPS-IL1RA-Stromal_mesenchymal-Fibroblasts-Pericyte_2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CHRDL2 TXNRD3 F8

6.95e-041584937f5426585d0d299d2b48e5fcb349950feffdef33
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_ALM_Cbln4_Fezf2|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

WNT9A PIP4K2C TPD52L1

7.21e-04160493d8241404d775f9a709abdf17988f36293fcf4c58
ToppCellLPS-IL1RA+antiTNF-Lymphocytic_NKT-iNKT/MAIT-T-cells|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ZNF74 MCM5 ZMAT1

7.21e-041604935c931e859acf67c1c8664941e0e44d195f8ba75b
ToppCellPND28-Immune-Immune_Myeloid-DC-cDC1-cDC1_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RPL36AL CYP8B1 PIP4K2A

7.34e-0416149376c993a4533362db2250c88b3ee3ede55362d54e
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast-Proliferative_MatrixFB|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

APOB RPS23 TPD52L1

7.48e-04162493b24298910eb39ea5103ae24439b3901205ed55b6
ToppCellPND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SLF1 WNT9A MCM5

7.48e-041624933f264263878af630921911c2b344ac56eb1e7099
ToppCell356C-Endothelial_cells-Endothelial-F_(Lymphatics)|356C / Donor, Lineage, Cell class and subclass (all cells)

BMX CHRDL2 F8

8.02e-041664936bd5aa205b6e4b88ba9f8cd0999e2191d7d1d16c
ToppCell356C-Endothelial_cells-Endothelial-F_(Lymphatics)-|356C / Donor, Lineage, Cell class and subclass (all cells)

BMX CHRDL2 F8

8.02e-041664935ba45407a47207ff01e4a3f9f5d91d8247fe9b6f
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-Stem_cells-ectodermal/neuroectodermal-like_cells|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

PTPN6 RPS23 TPD52L1

8.02e-04166493d7e49416426a62801ea1062d7aaf55ea622ae118
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c03-GZMK|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

ANKRD31 PIP4K2A F8

8.16e-04167493abc4ba308ca3be41b0da604f5d82579fd58dff7b
ToppCell3'-Child09-12-SmallIntestine-Hematopoietic-T_cells-NK_T_cell|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PTPN6 PIP4K2A ZNF730

8.31e-04168493b4b73f3fc9f4c3d87ca0a63ff8b2842141ccd0e6
ToppCellEndothelial-B-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

BMX APOB F8

8.45e-041694938889c9e8af1ab0b093d57b69abd80b59b3461be9
ToppCell356C-Endothelial_cells-Endothelial-B_(Artery)-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

CCNT2 ZNF346 PKP2

8.74e-041714936a2f88c2a62cb2f69797804e24eb1137a3e148de
ToppCell356C-Endothelial_cells-Endothelial-B_(Artery)|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

CCNT2 ZNF346 PKP2

8.74e-041714939be3554626408bb897d1f1c43b3ab4a92651f2e2
ToppCellfacs-Heart-LV-3m-Endothelial-endothelial_cell_of_endocardium|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BMX TXNRD3 PKP2

8.89e-04172493f2c17c49b375b28ad47dc6cabda62f1c238023dd
ToppCellfacs-Heart-LV-3m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BMX TXNRD3 PKP2

8.89e-041724936ab4f01098dddb789df298ddf97b3c384405ee6c
ToppCellBronchial_Biopsy-Endothelial-Lymphatic|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X

ZNF385D BMX CHRDL2

8.89e-04172493c41f5a66781bbf63afce7ca5d118cc6d8e0fe0bc
ToppCell3'-Airway_Nasal-Endothelial-Blood_vessel_EC|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ZNF385D RPS23 TPD52L1

9.04e-04173493b7d8702409b86fbc8741a472b84d509ba261a852
ToppCell3'-Airway_Nasal-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_systemic-EC_venous_systemic_L.2.2.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ZNF385D RPS23 TPD52L1

9.04e-04173493b83c9e274999c9325908616cee4a89d425c8c4ed
ToppCellfacs-Large_Intestine-Distal-24m-Epithelial-Brush_cell_of_epithelium_proper_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPN6 BMX ZNF385B

9.04e-04173493f0eb48c1283bdde313bb75f6ffc0d2626922d24b
ToppCell3'-Airway_Nasal-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_systemic|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ZNF385D RPS23 TPD52L1

9.04e-041734930068c059ef118b5ef85c5b01ad8680ce11493aa5
ToppCell3'-Airway_Nasal-Endothelial-Blood_vessel_EC-vein_endothelial_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ZNF385D RPS23 TPD52L1

9.04e-041734933c96e269ca7b7029f533268f68ca4466edd20edd
ToppCell3'-Airway_Nasal-Endothelial|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ZNF385D RPS23 TPD52L1

9.04e-04173493383edcd3bb14d3934506260dbbac7167282546af
ToppCellmetastatic_Lymph_Node-Endothelial_cells-Lymphatic_ECs|metastatic_Lymph_Node / Location, Cell class and cell subclass

ZNF385D BMX CHRDL2

9.19e-04174493d551bc29afef071adf4c9bb80345352ec33441d8
ToppCelldroplet|World / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPL36AL RPL36A RPS23

9.19e-0417449362553b0979e6d8f0b5fb95015f4d7adb116d6269
ToppCell368C-Endothelial_cells-Endothelial-D|368C / Donor, Lineage, Cell class and subclass (all cells)

ZNF385D F8 TPD52L1

9.34e-04175493c4088b5f9fa145869cf5dd8bee7680b1c8fada42
ToppCell368C-Endothelial_cells-Endothelial-D-|368C / Donor, Lineage, Cell class and subclass (all cells)

ZNF385D F8 TPD52L1

9.34e-04175493ca0d3e3a0a271cccdd3881b055fecb626712478d
ToppCellIIF-Lymphocyte-T_NK-CD4_TEM|IIF / Disease, Lineage and Cell Type

RPL36AL RPL36A RPS23

9.34e-041754930e7cde3bd638ab85abe915d40c432123f92af4fc
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHRDL2 RPL36A RPS23

9.50e-0417649312bccbd56742fcfe19749da802ea1cf62ec9a872
ToppCell3'-GW_trimst-2-LargeIntestine-Endothelial-lymphatic_endothelial-LEC2_(MADCAM1+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

BMX ZNF385B F8

9.66e-04177493d6596a0b6fd146fefc27717c1a7dbaa3774cc644
ToppCellmetastatic_Lymph_Node-Endothelial_cells|metastatic_Lymph_Node / Location, Cell class and cell subclass

ZNF385D BMX CHRDL2

9.66e-0417749371bf5d4bc67bda37a0499e5ec01af7dd5254041d
ToppCell3'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC1_(ACKR4+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

BMX CHRDL2 F8

9.66e-04177493dfaed388926ce050730492a532824af68bf4feff
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF385D ANK2 ZNF385B

9.81e-04178493dfed0fbf7a73b8a9e00178ec58dc4592b271c344
ToppCelldroplet-Lung-LUNG-30m-Myeloid-intermediate_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPN6 RPL36AL RPS23

9.81e-041784933c1246dccdebd6f504ffdfd6eba3a676db9d2e8a
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF385D ANK2 FRG2C

9.81e-041784934df6218b20c2f076c22346d23260964cc0d73e65
ToppCelldroplet-Lung-LUNG-30m-Myeloid-Intermediate_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPN6 RPL36AL RPS23

9.81e-0417849325a4545dbef4246cf6d27b9b5dde24881da6887e
ToppCell5'-Adult-LymphNode-Endothelial-lymphatic_endothelial-LEC6_(ADAMTS4+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

BMX CHRDL2 F8

9.97e-041794939fd9b136ecbcbd4e4f0d5875ede98d8d48608afb
ToppCell5'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC5_(CLDN11+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CYP8B1 HTRA4 F8

9.97e-0417949340c65e8623547aeb80f9cd2366e29072467ce069
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF385D ANK2 ZNF385B

9.97e-04179493d0fa700648db8ce76a8aa689879a25048299fa40
ToppCelldroplet|World / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPL36AL RPL36A RPS23

9.97e-041794931c29ecd294c140d73417bf1c11fe8bd3edd24eb7
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF385D ANK2 ZNF385B

9.97e-041794932e49b215b71438400aebb483f2c2c08d5e956961
ToppCell5'-Airway_Nasal-Epithelial-Neuro-endocrine/ionocytic-ionocyte-Ionocyte|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FSIP2 ANK2 PKP2

1.03e-031814932b53a65ca5616a7b9f64232c3e0b7212d1e2f063
ToppCell5'-Airway_Nasal-Epithelial-Neuro-endocrine/ionocytic-ionocyte|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FSIP2 ANK2 PKP2

1.03e-031814936aef84616e8d2faf54b7e9e6cd02f33c3066dabc
ToppCell367C-Endothelial_cells-Endothelial-F_(Lymphatics)-|367C / Donor, Lineage, Cell class and subclass (all cells)

BMX CHRDL2 F8

1.03e-03181493b244ecaa442bbef51289d8ec574ef08fa9e96318
ToppCelldroplet-Lung-30m-Hematologic-myeloid|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PTPN6 RPL36AL RPS23

1.03e-0318149375751d390812c98cc2b32ab578cdb15b34a80750
ToppCell5'-Airway_Nasal-Epithelial-Neuro-endocrine/ionocytic-ionocyte-Ionocyte-Ionocyte_L.0.7.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FSIP2 ANK2 PKP2

1.03e-0318149340df0afcb6848202da54670e84f22d7c3a515d01
ToppCell5'-Airway_Nasal-Epithelial-Neuro-endocrine/ionocytic|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FSIP2 ANK2 PKP2

1.03e-0318149340d3829ae4aaf81e8616c3499ff8933137fc1cc4
ToppCell367C-Endothelial_cells-Endothelial-F_(Lymphatics)|367C / Donor, Lineage, Cell class and subclass (all cells)

BMX CHRDL2 F8

1.03e-03181493dd79de8098edb385a0f85d0e9621503cdf76ec43
ToppCellPBMC-Control-cDC_12|Control / Compartment, Disease Groups and Clusters

SLF1 ZNF43 MCM5

1.05e-031824934774066d0f9986abc3d13a2a3bc99ce4f1327ae0
ToppCell5'-Adult-Appendix-Endothelial-lymphatic_endothelial-LEC6_(ADAMTS4+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ZNF385D CHRDL2 F8

1.05e-03182493fd786c88826ad3d5cc5c3d80f8e392d6be1b5267
ToppCellCOVID-19-Heart-Fib_+_EC_+_Pericyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

ZNF385D CHRDL2 F8

1.05e-03182493fbd5e332df73bf7141c822fa67b76367dc962017
ToppCelldroplet-Lung-LUNG|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPN6 RPL36AL RPS23

1.05e-03182493a7887b81d4da1a61763c6b02f33de19efb321d42
ToppCellE12.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_myogenic_precursor_(Axin2+)|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

RPL36AL NUP107 MCM5

1.06e-03183493523896bd1a93bdda81a009768baa3a1bdbd108b8
ToppCell5'-Adult-LymphNode-Endothelial-blood_vessel_EC-Mature_venous_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ZNF385D F8 TPD52L1

1.06e-03183493a644258ba90acc62d571623e429d72ffc4b69203
ToppCelldroplet-Lung-30m|Lung / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PTPN6 RPL36AL RPS23

1.06e-03183493c752a7abdca087e230935af867bf8ae829b3f0cb
ToppCell5'-Adult-LymphNode-Endothelial-lymphatic_endothelial-LEC1_(ACKR4+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

BMX CHRDL2 F8

1.06e-031834932d0d3b486498a7903fa9a1f48b189291da49c430
ToppCellMild/Remission-B_intermediate-10|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)

ANK2 PIP4K2A NEB

1.06e-03183493278064c9f0582463b83bf156d34e77f60187613b
ToppCelldroplet-Lung-LUNG-30m-Myeloid|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPN6 RPL36AL RPS23

1.06e-03183493f2e993c7fee631a0cc9d0c8f118f6da33a7c2296
ToppCell(6)_Endothelial-F_(Lymphatics)|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

BMX CHRDL2 F8

1.08e-0318449303ea613e00b45c81b752c14505a0538d698f551e
ToppCellLV-15._Ventricular_Cardiomyocyte_III|LV / Chamber and Cluster_Paper

ANK2 PKP2 TPD52L1

1.08e-03184493ab7a1620c14a9d9b6be1b47c559931e345e9eef8
ToppCell5'-Adult-Appendix-Endothelial-lymphatic_endothelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ZNF385D CHRDL2 F8

1.08e-03184493453295362888c9a59d0e73c7a5b15914c50ff591
ToppCelldroplet-Lung-LUNG-30m|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPN6 RPL36AL RPS23

1.08e-0318449352d62e1fcc92295d63197b2908083081b3ce1a6d
ToppCelldroplet-Limb_Muscle-Pre-Sort-18m-Mesenchymal-skeletal_muscle_satellite_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHRDL2 RPL36A RPS23

1.10e-031854935414a66169c39d09a67b1050aad5e61f46b3749a
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-lymphocytic-T_lymphocytic-CD8-positive,_alpha-beta_cytotoxic_T_cell|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

RPL36AL RPL36A RPS23

1.10e-03185493eeef122d64b48b950a4cf3948b64f4ffd9f3ebe0
ToppCellCOVID-19-Endothelial_cells-Systemic_venous_endothelial_cells|COVID-19 / group, cell type (main and fine annotations)

ZNF385D F8 TPD52L1

1.10e-03185493f5e14181f45c37d13ee9e017a4c8bc248c353676
ToppCelldroplet|World / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPL36AL RPL36A RPS23

1.10e-031854934c8a25f36cbf43fc78d38dfeb3f1cab160bb029d
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c05-FOS|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

RPL36AL RPL36A RPS23

1.10e-03185493f60b39010b9210a5f18ccd113758512bd15d7eec
ToppCellLV-15._Ventricular_Cardiomyocyte_III|World / Chamber and Cluster_Paper

ANK2 PKP2 TPD52L1

1.10e-031854936baccb26f999145e51b91d94315bf8d4655bef31
ToppCellCOVID-19-Neuronal_cells|COVID-19 / group, cell type (main and fine annotations)

ZNF385D CYP8B1 F8

1.10e-0318549336ce23893915f5c380cca39b2c33a516edf31c3a
ToppCellCOVID-19-Neuronal_cells-Neuronal_cells|COVID-19 / group, cell type (main and fine annotations)

ZNF385D CYP8B1 F8

1.10e-031854934a095829992b39856a73bdfac03ee68b9aa0d3b8
ToppCellSmart-seq2-bone_marrow_(Smart-seq2)-hematologic-hematopoietic_progenitor-hematopoietic_stem_cell|bone_marrow_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ZNF385D RPL36A RPS23

1.11e-03186493aefb9c186254ba7b02a5ae2bcea7bff2574178f7
ToppCelldroplet|World / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPL36AL RPL36A RPS23

1.11e-03186493fd69a94144710d63fe047cdc50813f42ac7ab68d
ToppCellnormal_Lung-Myeloid_cells-CD141+_DCs|normal_Lung / Location, Cell class and cell subclass

PKP2 MCM5 RPS23

1.11e-03186493a6698a2f4edd81b67e06531ede0e207dd0309205
ToppCelldroplet-Limb_Muscle-nan-21m-Mesenchymal-skeletal_muscle_satellite_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHRDL2 RPL36A RPS23

1.11e-031864931cbb1a1c4f0f6078e9c7b4e0dc93d6b6de7e57db
ToppCell(4)_Lymph_vessel|World / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)

BMX CHRDL2 F8

1.11e-031864936b3afc2ae870ff73e30a60ce84fcee0eb365d809
DiseaseUterine leiomyoma

ZNF346 NUP107 ZNF208

4.17e-0491473HP_0000131
DiseaseBrugada Syndrome (disorder)

ANK2 PKP2

6.70e-0424472C1142166
Diseasecholesterol to total lipids in small LDL percentage

ANKRD31 APOB

8.50e-0427472EFO_0022241
Diseasecholesterol to total lipids in medium LDL percentage

ANKRD31 APOB

8.50e-0427472EFO_0022238
Diseasecholesteryl ester 18:2 measurement

APOB ZMAT1

1.27e-0333472EFO_0010345
Diseasetriglycerides to total lipids in large VLDL percentage

ANKRD31 APOB

1.77e-0339472EFO_0022332

Protein segments in the cluster

PeptideGeneStartEntry
AAHYKGTKHAKKLKA

ZNF385D

96

Q9H6B1
VKQEYTHKAGSSKHH

CCNT2

406

O60583
QKNGLHHGKYAVKKS

CREBRF

466

Q8IUR6
SKAVNDKKGTVKHYH

BMX

336

P51813
DKKGTVKHYHVHTNA

BMX

341

P51813
EEYGKNHHNSSKKEK

FLG

171

P20930
HYKGHGKNHKDAASV

RANBP10

76

Q6VN20
KKVDKLNAAHYSTGK

PPIL2

231

Q13356
TFTEKVAHEHKEKKY

NUP107

781

P57740
HKTGLFEHKSAKQKQ

ANK2

2006

Q01484
VYQHKKPKFSSKSHI

ANKRD31

631

Q8N7Z5
IQKNKHKHKGVAASD

NLRC4

371

Q9NPP4
KGGSKTKHFQRKAAH

MGA

1091

Q8IWI9
KDFTKQKYPEHAIHK

MCM5

696

P33992
HIKGQSIISKHKYNK

FSIP2

616

Q5CZC0
KKHTAHFSKKGEEEN

F8

1281

P00451
EKHKKACVHGGKTYS

CHRDL2

246

Q6WN34
GKHQPHKVTQYKKGK

RPL36AL

16

Q969Q0
KGKGKTAFSHSSEKH

FRG2C

41

A6NGY1
LSVKAQYKKNKHRHS

APOB

3171

P04114
HEHQMKGKAFSNKKY

HTRA4

366

P83105
HKNPKTGIYEEKHAK

CANX

206

P27824
KVDFFKTGKKIHHYT

CYP8B1

416

Q9UNU6
AKKKAAHAAKTVKHG

PIP4K2A

366

P48426
AKKKAAHAAKTVKHG

PIP4K2C

381

Q8TBX8
GKHQPHKVTQYKKGK

RPL36A

16

P83881
ANLSKAEKHKYPHKV

RFC1

256

P35251
AEKHKYPHKVKTAQV

RFC1

261

P35251
KGNYKNHKLTHSGEK

FEZF1

356

A0PJY2
TKKKAAHAAKTVKHG

PIP4K2B

376

P78356
KWHDKQYKKAHLGTA

RPS23

21

P62266
FTKHKIIHTEGKSYK

ZNF92

496

Q03936
SEKGSKQQHKVHKYI

THOC2

836

Q8NI27
KAGHKANSKHKDKEQ

RPAP2

251

Q8IXW5
QAEAHYKGSKHAKKV

ZNF385B

171

Q569K4
KYQFHKTPVHKTKGE

nan

6

Q6ZUG5
LIQHHKKEKFSGSSK

SLF1

261

Q9BQI6
SSKHKEDVYENLHTK

PTPN6

556

P29350
HKKIHTGEKSYKCEE

ZNF730

191

Q6ZMV8
LTTHKKIHTGEKFYK

ZNF43

581

P17038
YKKTHETLSHAGQKA

TPD52L1

96

Q16890
VFSKHKKTHAGEKFY

ZNF208

931

O43345
SHYLGKTHAKNLKLK

ZNF346

151

Q9UL40
YEGKATDTTKHHKKK

TOPORS

871

Q9NS56
KHLKHKYETALKVGS

WNT9A

241

O14904
HHKIKATNKKGQETY

TXNRD3

281

Q86VQ6
HQKIHSGEKSFKCEK

ZNF74

546

Q16587
YCNKGFKKSSHLKQH

ZNF236

971

Q9UL36
SNFAKHKVHTGEKSY

ZNF732

236

B4DXR9
TELHHAYKKAQFKKT

PKP2

851

Q99959
AQSHYVGKVHAKKLK

ZMAT1

136

Q5H9K5
SELKYKAEHVKQKGH

NEB

4246

P20929
HVKEVTKHVSDTNYK

NEB

5676

P20929