Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionneurexin family protein binding

NLGN4Y SYTL2 NLGN3 NLGN4X

1.56e-06161114GO:0042043
GeneOntologyMolecularFunctionestrogen response element binding

ESRRB ESRRG NR3C2

2.67e-05111113GO:0034056
GeneOntologyMolecularFunctionextracellular matrix constituent, lubricant activity

MUC3A MUC4

1.82e-0441112GO:0030197
GeneOntologyMolecularFunctiontranscription factor binding

TCF7L2 PCLO ESRRB ZMYND8 GATA2 GATA3 SIN3A IKZF4 NFATC3 BAZ2A CD34 NR3C2 NOTCH2

2.81e-0475311113GO:0008134
GeneOntologyMolecularFunctionnuclear steroid receptor activity

ESRRB ESRRG NR3C2

3.52e-04251113GO:0003707
GeneOntologyBiologicalProcesspostsynaptic membrane assembly

NLGN4Y MAGI2 NLGN3 NLGN4X

2.83e-07111144GO:0097104
GeneOntologyBiologicalProcesspostsynaptic membrane organization

NLGN4Y ZMYND8 MAGI2 NLGN3 NLGN4X

1.44e-05561145GO:0001941
GeneOntologyBiologicalProcesspresynaptic membrane assembly

NLGN4Y NLGN3 NLGN4X

1.92e-05101143GO:0097105
GeneOntologyBiologicalProcesspresynaptic membrane organization

NLGN4Y NLGN3 NLGN4X

4.52e-05131143GO:0097090
GeneOntologyBiologicalProcessneuron cell-cell adhesion

NLGN4Y NLGN3 NLGN4X

8.74e-05161143GO:0007158
GeneOntologyBiologicalProcessterritorial aggressive behavior

NLGN4Y NLGN4X

9.05e-0531142GO:0002124
GeneOntologyCellularComponentsymmetric, GABA-ergic, inhibitory synapse

NLGN4Y NLGN3 NLGN4X

6.13e-0741133GO:0098983
GeneOntologyCellularComponentinhibitory synapse

NLGN4Y PCLO NLGN3 NLGN4X

2.28e-05311134GO:0060077
GeneOntologyCellularComponentGABA-ergic synapse

NLGN4Y PCLO WNK1 MAGI2 NLGN3 NLGN4X NR3C2

3.09e-051641137GO:0098982
GeneOntologyCellularComponentsymmetric synapse

NLGN4Y NLGN3 NLGN4X

4.23e-05131133GO:0032280
GeneOntologyCellularComponentasymmetric, glutamatergic, excitatory synapse

NLGN4Y NLGN3 NLGN4X

2.87e-04241133GO:0098985
GeneOntologyCellularComponentkeratohyalin granule

FLG FLG2

2.87e-0451132GO:0036457
GeneOntologyCellularComponentGolgi lumen

HSPG2 MUC16 MUC5B MUC3A MUC4

3.15e-041091135GO:0005796
GeneOntologyCellularComponentcentriole

DZIP1L RTTN NEDD1 CEP170 MAGI2 PCNT

3.47e-041721136GO:0005814
GeneOntologyCellularComponentciliary basal body

DLG5 DZIP1L RTTN NEDD1 PTK2 PCNT

6.74e-041951136GO:0036064
GeneOntologyCellularComponentasymmetric synapse

DLG5 GPR50 NLGN4Y PCLO DNAJC6 MAGI2 NLGN3 NLGN4X NR3C2

1.14e-034771139GO:0032279
GeneOntologyCellularComponentpostsynaptic specialization

DLG5 GPR50 NLGN4Y PCLO DNAJC6 MAGI2 NLGN3 NLGN4X NR3C2

1.65e-035031139GO:0099572
DomainNlgn

NLGN4Y NLGN3 NLGN4X

2.03e-0651113IPR000460
DomainSEA

HSPG2 MUC16 UMODL1 MUC3A

9.59e-06231114PS50024
DomainSEA_dom

HSPG2 MUC16 UMODL1 MUC3A

9.59e-06231114IPR000082
DomainFHA

KIF13B FOXK2 CEP170 CHEK2

2.17e-05281114SM00240
Domain-

ESRRB ESRRG GATA2 GATA3 NR3C2

2.22e-055711153.30.50.10
DomainZnf_NHR/GATA

ESRRB ESRRG GATA2 GATA3 NR3C2

2.41e-05581115IPR013088
DomainFHA_DOMAIN

KIF13B FOXK2 CEP170 CHEK2

3.28e-05311114PS50006
DomainFHA

KIF13B FOXK2 CEP170 CHEK2

3.28e-05311114PF00498
DomainNLGN4

NLGN4Y NLGN4X

3.50e-0521112IPR030025
DomainFilaggrin

FLG FLG2

3.50e-0521112IPR003303
DomainCarboxylesterase_B_CS

NLGN4Y NLGN3 NLGN4X

5.59e-05131113IPR019819
DomainFHA_dom

KIF13B FOXK2 CEP170 CHEK2

6.01e-05361114IPR000253
Domain-

KIF13B FOXK2 CEP170 CHEK2

6.01e-053611142.60.200.20
DomainSEA

HSPG2 MUC16 MUC3A

7.09e-05141113SM00200
DomainCARBOXYLESTERASE_B_2

NLGN4Y NLGN3 NLGN4X

7.09e-05141113PS00941
DomainCOesterase

NLGN4Y NLGN3 NLGN4X

7.09e-05141113PF00135
DomainCarbesteraseB

NLGN4Y NLGN3 NLGN4X

7.09e-05141113IPR002018
DomainOest-rel_rcp

ESRRB ESRRG

1.05e-0431112IPR027289
DomainTF_GATA-2/3

GATA2 GATA3

1.05e-0431112IPR016374
DomainDUF1908

MAST2 MAST1

2.08e-0441112PF08926
DomainMA_Ser/Thr_Kinase_dom

MAST2 MAST1

2.08e-0441112IPR015022
DomainMAST_pre-PK_dom

MAST2 MAST1

2.08e-0441112IPR023142
Domain-

MAST2 MAST1

2.08e-04411121.20.1480.20
DomainZnf_FYVE_PHD

PCLO SYTL2 ZMYND8 KMT2E RBSN BAZ2A

2.46e-041471116IPR011011
DomainSMAD_FHA_domain

KIF13B FOXK2 CEP170 CHEK2

2.57e-04521114IPR008984
DomainPDZ

DLG5 PCLO MAST2 MAGI2 MAST1 SNTG2

2.85e-041511116PS50106
DomainSEA

HSPG2 MUC16 UMODL1

2.90e-04221113PF01390
DomainPDZ

DLG5 PCLO MAST2 MAGI2 MAST1 SNTG2

2.95e-041521116IPR001478
DomainOest_rcpt/oest-rel_rcp

ESRRB ESRRG

3.46e-0451112IPR024178
DomainRetinoid-X_rcpt/HNF4

ESRRB ESRRG

1.53e-03101112IPR000003
DomainPDZ

DLG5 MAST2 MAGI2 MAST1 SNTG2

1.54e-031411115PF00595
DomainIntegrin_alpha

ITGAD ITGAM

1.86e-03111112PF00357
DomainPDZ

DLG5 MAST2 MAGI2 MAST1 SNTG2

1.91e-031481115SM00228
Domain-

DLG5 MAST2 MAGI2 MAST1 SNTG2

2.02e-0315011152.30.42.10
DomainZnF_GATA

GATA2 GATA3

2.22e-03121112SM00401
Domainzf-C4

ESRRB ESRRG NR3C2

2.58e-03461113PF00105
DomainZnf_hrmn_rcpt

ESRRB ESRRG NR3C2

2.58e-03461113IPR001628
DomainNUCLEAR_REC_DBD_2

ESRRB ESRRG NR3C2

2.58e-03461113PS51030
DomainNUCLEAR_REC_DBD_1

ESRRB ESRRG NR3C2

2.58e-03461113PS00031
DomainZnF_C4

ESRRB ESRRG NR3C2

2.58e-03461113SM00399
DomainRoc

AGAP1 AGAP3

2.62e-03131112PF08477
DomainMIRO-like

AGAP1 AGAP3

2.62e-03131112IPR013684
Domain-

ESRRB ESRRG NR3C2

2.74e-034711131.10.565.10
DomainHOLI

ESRRB ESRRG NR3C2

2.91e-03481113SM00430
DomainNucl_hrmn_rcpt_lig-bd

ESRRB ESRRG NR3C2

2.91e-03481113IPR000536
DomainHormone_recep

ESRRB ESRRG NR3C2

2.91e-03481113PF00104
DomainZnf_GATA

GATA2 GATA3

3.49e-03151112IPR000679
DomainGATA

GATA2 GATA3

3.49e-03151112PF00320
DomainVWD

MUC5B MUC4

3.98e-03161112SM00216
DomainGATA_ZN_FINGER_1

GATA2 GATA3

3.98e-03161112PS00344
DomainIntegrin_alpha_C_CS

ITGAD ITGAM

3.98e-03161112IPR018184
DomainVWF_type-D

MUC5B MUC4

3.98e-03161112IPR001846
DomainVWFD

MUC5B MUC4

3.98e-03161112PS51233
DomainGATA_ZN_FINGER_2

GATA2 GATA3

3.98e-03161112PS50114
DomainVWD

MUC5B MUC4

3.98e-03161112PF00094
DomainVWA

ITGAD ITGAM VWA3B

4.50e-03561113PF00092
DomainIntegrin_alpha-2

ITGAD ITGAM

5.03e-03181112IPR013649
DomainIntegrin_alpha2

ITGAD ITGAM

5.03e-03181112PF08441
DomainIntegrin_alpha

ITGAD ITGAM

5.03e-03181112IPR000413
DomainINTEGRIN_ALPHA

ITGAD ITGAM

5.03e-03181112PS00242
DomainInt_alpha_beta-p

ITGAD ITGAM

5.60e-03191112IPR013519
DomainInt_alpha

ITGAD ITGAM

5.60e-03191112SM00191
PathwayREACTOME_DEFECTIVE_GALNT3_CAUSES_HFTC

MUC16 MUC5B MUC3A MUC4

1.84e-0616824M27410
PathwayREACTOME_DEFECTIVE_C1GALT1C1_CAUSES_TNPS

MUC16 MUC5B MUC3A MUC4

2.39e-0617824M27412
PathwayREACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS

MUC16 MUC5B MUC3A MUC4

8.66e-0623824M556
PathwayREACTOME_DECTIN_2_FAMILY

MUC16 MUC5B MUC3A MUC4

1.44e-0526824M27483
PathwayREACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS

MUC16 MUC5B MUC3A MUC4 NOTCH2

4.61e-0568825M27303
PathwayREACTOME_MITF_M_DEPENDENT_GENE_EXPRESSION

TCF7L2 SYTL2 SIN3A

1.01e-0416823MM17241
PathwayREACTOME_DISEASES_OF_GLYCOSYLATION

HSPG2 MUC16 MUC5B MUC3A MUC4 NOTCH2

1.82e-04143826M27275
PathwayREACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS

MUC16 MUC5B MUC4

2.34e-0421823MM15706
PathwayREACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS

MUC16 MUC5B MUC3A MUC4

4.59e-0462824M546
Pubmed

Neuroligins 3 and 4X interact with syntrophin-gamma2, and the interactions are affected by autism-related mutations.

NLGN4Y NLGN3 NLGN4X SNTG2

1.17e-104116417292328
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

KIF13B DLG5 TEX2 WWTR1 MAST2 ARHGEF17 WNK1 CEP170 NHSL1 RBSN NFATC3 XRN1 RBM7 NR3C2 NOTCH2 AGAP3

3.00e-088611161636931259
Pubmed

GATA3 regulates FLG and FLG2 expression in human primary keratinocytes.

FLG GATA3 FLG2

3.62e-083116328928464
Pubmed

Evolution of the Autism-Associated Neuroligin-4 Gene Reveals Broad Erosion of Pseudoautosomal Regions in Rodents.

NLGN4Y NLGN3 NLGN4X

3.62e-083116332011705
Pubmed

Analysis of the neuroligin 4Y gene in patients with autism.

NLGN4Y NLGN3 NLGN4X

3.62e-083116318628683
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

TCF7L2 FOXK2 SGSM1 NLGN4Y TRIOBP TNRC6C NEDD1 UBN2 PTK2 PCNX2 CEP170 NLGN3 KIDINS220 MAST1 SNTG2 NOTCH2 AGAP1 PCNT AGAP3 FAM149A

1.05e-0714891162028611215
Pubmed

A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.

TCF7L2 FOXK2 ESRRB ESRRG ZMYND8 GATA2 GATA3 PRDM4 IKZF4 ZIC4 RBSN BAZ2A NR3C2 MNT

1.13e-077091161422988430
Pubmed

Mutations of the X-linked genes encoding neuroligins NLGN3 and NLGN4 are associated with autism.

NLGN4Y NLGN3 NLGN4X

1.44e-074116312669065
Pubmed

Homodimerization and isoform-specific heterodimerization of neuroligins.

NLGN4Y NLGN3 NLGN4X

1.44e-074116322671294
Pubmed

Ultrasonic vocalizations in mouse models for speech and socio-cognitive disorders: insights into the evolution of vocal communication.

NLGN4Y NLGN3 NLGN4X

1.44e-074116320579107
Pubmed

Analysis of four neuroligin genes as candidates for autism.

NLGN4Y NLGN3 NLGN4X

1.44e-074116316077734
Pubmed

Mucin gene expression in human laryngeal epithelia: effect of laryngopharyngeal reflux.

MUC16 MUC5B MUC3A MUC4

3.47e-0718116418834073
Pubmed

Multiple N-linked glycosylation sites critically modulate the synaptic abundance of neuroligin isoforms.

NLGN4Y NLGN3 NLGN4X

3.60e-075116337865312
Pubmed

Synapse formation: if it looks like a duck and quacks like a duck ...

NLGN4Y NLGN3 NLGN4X

3.60e-075116310996085
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

ZSWIM8 PCLO ESRRG ZMYND8 MAST2 GCN1

4.90e-0787116612465718
Pubmed

The synaptic protein neuroligin-1 interacts with the amyloid β-peptide. Is there a role in Alzheimer's disease?

NLGN4Y NLGN3 NLGN4X

7.18e-076116321838267
Pubmed

Autism-associated neuroligin-4 mutation selectively impairs glycinergic synaptic transmission in mouse brainstem synapses.

NLGN4Y NLGN3 NLGN4X

7.18e-076116329724786
Pubmed

Direct protein interactions are responsible for Ikaros-GATA and Ikaros-Cdk9 cooperativeness in hematopoietic cells.

GATA2 GATA3 IKZF4

7.18e-076116323732910
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

HSPG2 FOXK2 TMEM94 RTTN GATA2 TNRC6C MAST2 WNK1 PCNX2 NHSL1 KCTD15 UNKL GCN1 NOTCH2 PCNT AGAP3

8.57e-0711051161635748872
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

TMEM94 TNRC6C SMC5 ARHGEF17 DNAJC6 MAGI2 KIDINS220 BAZ2A MAST1 PCNT

1.17e-064071161012693553
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

TCF7L2 AFF2 ZMYND8 SIN3A KMT2E PRDM4 WNK1 PTK2 SCN10A PCNT

1.91e-064301161035044719
Pubmed

Neuroligin-1 Signaling Controls LTP and NMDA Receptors by Distinct Molecular Pathways.

NLGN4Y NLGN3 NLGN4X

2.00e-068116330871858
Pubmed

Using mouse models of autism spectrum disorders to study the neurotoxicology of gene-environment interactions.

NLGN4Y NLGN3 NLGN4X

2.99e-069116323010509
Pubmed

Rewiring of RSK-PDZ Interactome by Linear Motif Phosphorylation.

MAST2 MAGI2 MAST1 SNTG2

5.04e-0634116430726710
Pubmed

A high-resolution molecular atlas of the fetal mouse lower urogenital tract.

ESRRG GATA2 PTK2 EDAR BAZ2A

5.42e-0675116521905163
Pubmed

SPARCL1 Promotes Excitatory But Not Inhibitory Synapse Formation and Function Independent of Neurexins and Neuroligins.

NLGN4Y NLGN3 NLGN4X

5.85e-0611116332973045
Pubmed

Behavioral phenotypes of genetic mouse models of autism.

NLGN4Y NLGN3 NLGN4X

5.85e-0611116326403076
Pubmed

Quantifying domain-ligand affinities and specificities by high-throughput holdup assay.

MAST2 MAGI2 MAST1 SNTG2

6.37e-0636116426053890
Pubmed

Advancing the understanding of autism disease mechanisms through genetics.

NLGN4Y NLGN3 NLGN4X

1.01e-0513116327050589
Pubmed

Expression of estrogen-related receptors in ovarian cancer and impact on survival.

ESRRB ESRRG

1.10e-052116234089362
Pubmed

Association Analysis of Noncoding Variants in Neuroligins 3 and 4X Genes with Autism Spectrum Disorder in an Italian Cohort.

NLGN3 NLGN4X

1.10e-052116227782075
Pubmed

Not all neuroligin 3 and 4X missense variants lead to significant functional inactivation.

NLGN3 NLGN4X

1.10e-052116228948087
Pubmed

Novel splice isoforms for NLGN3 and NLGN4 with possible implications in autism.

NLGN3 NLGN4X

1.10e-052116216648374
Pubmed

A substitution involving the NLGN4 gene associated with autistic behavior in the Greek population.

NLGN3 NLGN4X

1.10e-052116219645625
Pubmed

GATA motifs regulate early hematopoietic lineage-specific expression of the Gata2 gene.

GATA2 GATA3

1.10e-052116216055713
Pubmed

Mutation screening of X-chromosomal neuroligin genes: no mutations in 196 autism probands.

NLGN3 NLGN4X

1.10e-052116215274046
Pubmed

Inhibition of integrin αDβ2-mediated macrophage adhesion to end product of docosahexaenoic acid (DHA) oxidation prevents macrophage accumulation during inflammation.

ITGAD ITGAM

1.10e-052116231395659
Pubmed

Mechanistic Understanding of Cell Recognition and Immune Reaction via CR1/CR3 by HAP- and SiO2-NPs.

CR1 ITGAM

1.10e-052116232382571
Pubmed

Development of an autism severity score for mice using Nlgn4 null mutants as a construct-valid model of heritable monogenic autism.

NLGN4Y NLGN4X

1.10e-052116223183221
Pubmed

Juvenile manifestation of ultrasound communication deficits in the neuroligin-4 null mutant mouse model of autism.

NLGN4Y NLGN4X

1.10e-052116224855039
Pubmed

Sex-specific microglia state in the Neuroligin-4 knock-out mouse model of autism spectrum disorder.

NLGN4Y NLGN4X

1.10e-052116237001827
Pubmed

GATA2-dependent and region-specific regulation of Gata2 transcription in the mouse midbrain.

GATA2 GATA3

1.10e-052116219371385
Pubmed

The GATA transcriptional program dictates cell fate equilibrium to establish the maternal-fetal exchange interface and fetal development.

GATA2 GATA3

1.10e-052116238346193
Pubmed

Immunocytochemistry for MUC4 and MUC16 is a useful adjunct in the diagnosis of pancreatic adenocarcinoma on fine-needle aspiration cytology.

MUC16 MUC4

1.10e-052116223544943
Pubmed

No evidence for involvement of genetic variants in the X-linked neuroligin genes NLGN3 and NLGN4X in probands with autism spectrum disorder on high functioning level.

NLGN3 NLGN4X

1.10e-052116218189281
Pubmed

Expression of mucins in mucoid otitis media.

MUC5B MUC4

1.10e-052116214690056
Pubmed

The essential role of GATA transcription factors in adult murine prostate.

GATA2 GATA3

1.10e-052116227374105
Pubmed

Disorder-associated mutations lead to functional inactivation of neuroligins.

NLGN3 NLGN4X

1.10e-052116215150161
Pubmed

GATA3 is downregulated during hair cell differentiation in the mouse cochlea.

GATA2 GATA3

1.10e-052116210447238
Pubmed

Analysis of the neuroligin 3 and 4 genes in autism and other neuropsychiatric patients.

NLGN3 NLGN4X

1.10e-052116215622415
Pubmed

Context-dependent function of regulatory elements and a switch in chromatin occupancy between GATA3 and GATA2 regulate Gata2 transcription during trophoblast differentiation.

GATA2 GATA3

1.10e-052116219106099
Pubmed

DLG5 suppresses breast cancer stem cell-like characteristics to restore tamoxifen sensitivity by inhibiting TAZ expression.

DLG5 WWTR1

1.10e-052116230450766
Pubmed

Oral administration of K-11706 inhibits GATA binding activity, enhances hypoxia-inducible factor 1 binding activity, and restores indicators in an in vivo mouse model of anemia of chronic disease.

GATA2 GATA3

1.10e-052116215328158
Pubmed

Detailed analysis of bone marrow from patients with ischemic heart disease and left ventricular dysfunction: BM CD34, CD11b, and clonogenic capacity as biomarkers for clinical outcomes.

ITGAM CD34

1.10e-052116225136078
Pubmed

Unusually rapid evolution of Neuroligin-4 in mice.

NLGN4Y NLGN4X

1.10e-052116218434543
Pubmed

Analysis of the genes encoding neuroligins NLGN3 and NLGN4 in Bulgarian patients with autism.

NLGN3 NLGN4X

1.10e-052116223431752
Pubmed

Increased Network Inhibition in the Dentate Gyrus of Adult Neuroligin-4 Knock-Out Mice.

NLGN4Y NLGN4X

1.10e-052116237080762
Pubmed

Zinc improves the development of human CD34+ cell progenitors towards NK cells and increases the expression of GATA-3 transcription factor in young and old ages.

GATA3 CD34

1.10e-052116219043799
Pubmed

Identification of two hERR2-related novel nuclear receptors utilizing bioinformatics and inverse PCR.

ESRRB ESRRG

1.10e-052116210072763
Pubmed

Absence of coding mutations in the X-linked genes neuroligin 3 and neuroligin 4 in individuals with autism from the IMGSAC collection.

NLGN3 NLGN4X

1.10e-052116216508939
Pubmed

Autism Related Neuroligin-4 Knockout Impairs Intracortical Processing but not Sensory Inputs in Mouse Barrel Cortex.

NLGN4Y NLGN4X

1.10e-052116229106499
Pubmed

NLGN3/NLGN4 gene mutations are not responsible for autism in the Quebec population.

NLGN3 NLGN4X

1.10e-052116215389766
Pubmed

Perturbed Hippocampal Synaptic Inhibition and γ-Oscillations in a Neuroligin-4 Knockout Mouse Model of Autism.

NLGN4Y NLGN4X

1.10e-052116226456829
Pubmed

An ERRbeta/gamma agonist modulates GRalpha expression, and glucocorticoid responsive gene expression in skeletal muscle cells.

ESRRB ESRRG

1.10e-052116219631715
Pubmed

Nlgn4 knockout induces network hypo-excitability in juvenile mouse somatosensory cortex in vitro.

NLGN4Y NLGN4X

1.10e-052116224104404
Pubmed

GATA factor activity is required for the trophoblast-specific transcriptional regulation of the mouse placental lactogen I gene.

GATA2 GATA3

1.10e-05211627720565
Pubmed

A Cluster of Autism-Associated Variants on X-Linked NLGN4X Functionally Resemble NLGN4Y.

NLGN4Y NLGN4X

1.10e-052116232243781
Pubmed

Absence of deficits in social behaviors and ultrasonic vocalizations in later generations of mice lacking neuroligin4.

NLGN4Y NLGN4X

1.10e-052116222989184
Pubmed

Variations analysis of NLGN3 and NLGN4X gene in Chinese autism patients.

NLGN3 NLGN4X

1.10e-052116224570023
Pubmed

Complement receptor 3 mediates Aspergillus fumigatus internalization into alveolar epithelial cells with the increase of intracellular phosphatidic acid by activating FAK.

ITGAM PTK2

1.10e-052116234338598
Pubmed

Rhinovirus colocalizes with CD68- and CD11b-positive macrophages following experimental infection in humans.

ITGAM CD68

1.10e-052116223727038
Pubmed

Mutation screening in the Greek population and evaluation of NLGN3 and NLGN4X genes causal factors for autism.

NLGN3 NLGN4X

1.10e-052116223851596
Pubmed

Expression of filaggrin-2 protein in the epidermis of human skin diseases: a comparative analysis with filaggrin.

FLG FLG2

1.10e-052116224813994
Pubmed

Reduced social interaction and ultrasonic communication in a mouse model of monogenic heritable autism.

NLGN4Y NLGN3 NLGN4X

1.60e-0515116318227507
Pubmed

Genomic analysis of mouse retinal development.

ZSWIM8 IL15RA TCF7L2 TMEM94 ESRRB UBN2 MAST2 PTK2 RBSN BAZ2A KCTD15 MAST1 MNT

3.24e-0510061161315226823
Pubmed

GATA suppresses erythropoietin gene expression through GATA site in mouse erythropoietin gene promoter.

GATA2 GATA3

3.30e-053116212041667
Pubmed

Notch2-dependent GATA3+ Treg cells alleviate allergic rhinitis by suppressing the Th2 cell response.

GATA3 NOTCH2

3.30e-053116236155282
Pubmed

Microbial products alter the expression of membrane-associated mucin and antimicrobial peptides in a three-dimensional human endocervical epithelial cell model.

MUC16 MUC4

3.30e-053116223053434
Pubmed

Functionally recurrent rearrangements of the MAST kinase and Notch gene families in breast cancer.

MAST2 MAST1

3.30e-053116222101766
Pubmed

HBV suppresses expression of MICA/B on hepatoma cells through up-regulation of transcription factors GATA2 and GATA3 to escape from NK cell surveillance.

GATA2 GATA3

3.30e-053116227528231
Pubmed

Integrative analysis of the cancer genome atlas and cancer cell lines encyclopedia large-scale genomic databases: MUC4/MUC16/MUC20 signature is associated with poor survival in human carcinomas.

MUC16 MUC4

3.30e-053116230236127
Pubmed

GATA-1, -2 and -3 genes expression in bone marrow microenviroment with chronic aplastic anemia.

GATA2 GATA3

3.30e-053116217654061
Pubmed

Hematopoietic (stem) cell development - how divergent are the roads taken?

GATA2 CD34

3.30e-053116227543859
Pubmed

Significance of neurexin and neuroligin polymorphisms in regulating risk of Hirschsprung's disease.

NLGN3 NLGN4X

3.30e-053116229622757
Pubmed

Regulation of endogenous retrovirus-derived regulatory elements by GATA2/3 and MSX2 in human trophoblast stem cells.

GATA2 GATA3

3.30e-053116236806146
Pubmed

Estrogen-Related Receptors Mediate the Adaptive Response of Brown Adipose Tissue to Adrenergic Stimulation.

ESRRB ESRRG

3.30e-053116229888756
Pubmed

Repression via the GATA box is essential for tissue-specific erythropoietin gene expression.

GATA2 GATA3

3.30e-053116218202227
Pubmed

Iterative Single-Cell Analyses Define the Transcriptome of the First Functional Hematopoietic Stem Cells.

GATA2 CD34

3.30e-053116232402290
Pubmed

Bile acids-mediated overexpression of MUC4 via FAK-dependent c-Jun activation in pancreatic cancer.

PTK2 MUC4

3.30e-053116227185392
Pubmed

Three-gene prognostic biomarkers for seminoma identified by weighted gene co-expression network analysis.

ITGAM CD68

3.30e-053116233104706
Pubmed

Cytokine and integrin stimulation synergize to promote higher levels of GATA-2, c-myb, and CD34 protein in primary human hematopoietic progenitors from bone marrow.

GATA2 CD34

3.30e-053116217095623
Pubmed

Expression and functional study of estrogen receptor-related receptors in human prostatic cells and tissues.

ESRRB ESRRG

3.30e-053116215598686
Pubmed

Filaggrin and filaggrin 2 processing are linked together through skin aspartic acid protease activation.

FLG FLG2

3.30e-053116232437351
Pubmed

Axed MUC4 (MUC4/X) aggravates pancreatic malignant phenotype by activating integrin-β1/FAK/ERK pathway.

PTK2 MUC4

3.30e-053116229777904
Pubmed

T Cell Factor 4 Is Involved in Papillary Thyroid Carcinoma via Regulating Long Non-Coding RNA HCP5.

TCF7L2 HCP5

3.30e-053116233371788
Pubmed

Functional Consequences of Differential O-glycosylation of MUC1, MUC4, and MUC16 (Downstream Effects on Signaling).

MUC16 MUC4

3.30e-053116227483328
Pubmed

MicroRNA-200c modulates the expression of MUC4 and MUC16 by directly targeting their coding sequences in human pancreatic cancer.

MUC16 MUC4

3.30e-053116224204560
Pubmed

The Role of Integrins αMβ2 (Mac-1, CD11b/CD18) and αDβ2 (CD11d/CD18) in Macrophage Fusion.

ITGAD ITGAM

3.30e-053116227315778
Pubmed

CHK2-FOXK axis promotes transcriptional control of autophagy programs.

FOXK2 CHEK2

3.30e-053116231911943
Pubmed

Expression of the transmembrane mucins, MUC1, MUC4 and MUC16, in normal endometrium and in endometriosis.

MUC16 MUC4

3.30e-053116224939955
InteractionYWHAH interactions

KIF13B DLG5 NHSL2 TEX2 WWTR1 MAST2 ARHGEF17 WNK1 CEP170 NHSL1 RBSN NFATC3 XRN1 RBM7 MAST1 NR3C2 NOTCH2 AGAP1 PCNT AGAP3

3.42e-06110211420int:YWHAH
GeneFamilyCD molecules|Mucins

MUC16 MUC5B MUC3A MUC4

1.31e-0621724648
GeneFamilyPDZ domain containing

DLG5 PCLO MAST2 MAGI2 MAST1 SNTG2

3.16e-051527261220
GeneFamilyEF-hand domain containing|S100 fused type protein family

FLG FLG2

3.24e-0477221350
GeneFamilyADAM metallopeptidase domain containing|CD molecules

IL15RA ITGAD CR1 ITGAM TNFSF8 CD34 CD68

9.65e-04394727471
GeneFamilyNuclear hormone receptors

ESRRB ESRRG NR3C2

9.78e-044972371
GeneFamilyGATA zinc finger domain containing|Myb/SANT domain containing

GATA2 GATA3

1.59e-031572282
GeneFamilyX-linked mental retardation|Rho GTPase activating proteins|BAR-PH domain containing

AGAP1 AGAP3

2.05e-03177221291
GeneFamilyCD molecules|Integrin alpha subunits

ITGAD ITGAM

2.30e-03187221160
GeneFamilyCalcium voltage-gated channel subunits|Membrane associated guanylate kinases

DLG5 MAGI2

4.78e-0326722904
GeneFamilyPHD finger proteins

ZMYND8 KMT2E BAZ2A

5.55e-039072388
GeneFamilyArfGAPs

AGAP1 AGAP3

7.62e-0333722395
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HGABA

PSD2 AFF2 PCLO ESRRG VSTM2A SYTL2 ZMYND8 GATA3 SIN3A TNRC6C IRGQ KMT2E UBN2 DNAJC6 IKZF4 MAGI2 NLGN4X MAST1 CACNA1I AGAP1

6.96e-08110611520M39071
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HNBML5

PSD2 AFF2 ESRRG VSTM2A SYTL2 GATA2 GATA3 IRGQ UBN2 DNAJC6 MAST1

6.61e-0646511511M39066
CoexpressionPEREZ_TP53_TARGETS

FLG DLG5 GATA2 GATA3 TNRC6C IRGQ TYSND1 ITGAM ARHGEF17 DNAJC6 EDAR UMODL1 UNKL MN1 AGAP1 AGAP3 FAM149A

1.93e-05120111517M4391
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

TCF7L2 FOXK2 ZMYND8 WWTR1 SMC5 MAST2 PTK2 CEP170 KIDINS220 NFATC3 MN1 MNT AGAP1 PCNT

2.37e-0585611514M4500
CoexpressionGSE8515_IL1_VS_IL6_4H_STIM_MAC_DN

ARHGEF17 WNK1 MAGI2 CHEK2 SNTG2 CACNA1I UTY

2.44e-051941157M5767
CoexpressionGAO_LARGE_INTESTINE_24W_C8_GOBLET_CELL

SYTL2 ZMYND8 MUC5B MUC4

3.14e-05411154M39158
CoexpressionSTREICHER_LSM1_TARGETS_UP

IL15RA GATA2 GATA3 NR3C2

4.17e-05441154M15031
ToppCelldroplet-Lung-30m-Hematologic-myeloid-alveolar_macrophage-proliferating_alveolar_macrophage|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TCF7L2 PCLO ESRRG VSTM2A SLC18A1 AGAP1 AGAP3

5.67e-071851167b4af9ae4c358b48357cb135b740266e1652d886a
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SGSM1 ESRRB ESRRG GATA3 WNK1 TMEM213 NR3C2

6.32e-071881167bc089cd73d283ed7d2ecbb3936673b4edc89f666
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SGSM1 ESRRB ESRRG GATA3 WNK1 TMEM213 NR3C2

6.32e-071881167eec3d353e51358db4c7621265ee0fdd4298e5b0e
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SGSM1 ESRRB ESRRG WNK1 MAGI2 MAGEB10

3.68e-0615811667960337d87afecf2692ab65e5991f052ceddfacc
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF13B AFF2 TMEM94 PCLO ITGAD MUC4

6.40e-061741166f1fe1f4216748a9562dd03bd48c70b23c7ff4d1d
ToppCellE16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HSPG2 NHSL2 ESRRG GATA2 GATA3 CD34

6.84e-06176116677516048aefbe1f48e825052756df0c310c1c486
ToppCell3'-Adult-SmallIntestine-Endothelial-blood_vessel_EC-Mature_arterial_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NHSL2 GATA2 WWTR1 WNK1 CD34 SNTG2

7.29e-061781166e2363810d77b6b245394a666eb51bacd345c43f7
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DLG5 SYTL2 MUC16 MUC5B MUC4 MNT

7.53e-0617911666e965e424eebef50f0202cff75f458be395cfca1
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SGSM1 ESRRB ESRRG WNK1 MAGI2 MAGEB10

8.02e-061811166e0abf2707d9e0aa942c657eef7d2cbcd02f060dd
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ESRRB ESRRG GATA3 WNK1 TMEM213 NR3C2

8.28e-0618211665f513bbb7125956eb528e3120de3fd776770a7c3
ToppCellControl-Epithelial_cells-Airway_mucous|Control / group, cell type (main and fine annotations)

TCF7L2 MUC16 MUC5B MUC3A MUC4 AGAP1

8.54e-06183116615d24a4fb1ffe6cbafbd54fcd7dde9ddcfbe03b2
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ESRRB ESRRG GATA3 WNK1 TMEM213 NR3C2

8.54e-0618311662e831a4d99c6f983793df71c0994124c943c6da9
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Degenerative_Connecting_Tubule_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SYTL2 GATA2 GATA3 WNK1 TMEM213 NR3C2

9.37e-061861166b3358e0fa6d845c81e94d56c8575f016621d28ff
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

NLGN4Y ESRRB ESRRG SYTL2 WWTR1 NR3C2

9.66e-06187116677886f99c229610abd28c4c370d2c7d1536c9782
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SGSM1 ESRRB ESRRG WNK1 TMEM213 NR3C2

1.03e-051891166f51cdc9a47371cab8ed9ae63a6f14da07ede446c
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SGSM1 ESRRB ESRRG WNK1 TMEM213 NR3C2

1.03e-051891166977a813e5d7a5a561c1fced2bbf21c20056b88d8
ToppCellrenal_medulla_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

ESRRB ESRRG ZMYND8 PTK2 NR3C2 UTY

1.03e-051891166830d9cd0dd706bce22eb2416f07b2c31c870a05a
ToppCellCOVID-19-Endothelial_cells-Endothelial_cells_(general)|COVID-19 / group, cell type (main and fine annotations)

GATA2 WWTR1 PTK2 NLGN4X CD34 SNTG2

1.06e-051901166812e11314c76c0179fbe5a9bea29b41ce5cbc93d
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SGSM1 ESRRB ESRRG WNK1 TMEM213 NR3C2

1.06e-051901166b94df372bc08de11585b2467dba8c8fffff5cd92
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SGSM1 ESRRB ESRRG WNK1 TMEM213 NR3C2

1.06e-051901166e252e925600e6457fa6e362a55217f4cffa75cdb
ToppCellfacs-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l20-25|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

IL15RA SYTL2 SBSN NHSL1 FNDC1 CD34

1.12e-05192116630cefa0990ba1f379f350bfbf994a78db145075e
ToppCellTCGA-Adrenal-Primary_Tumor-Pheochromocytoma|TCGA-Adrenal / Sample_Type by Project: Shred V9

VSTM2A GATA2 GATA3 ARHGEF17 SLC18A1 MAST1

1.19e-051941166b6488bc3a8905e926ad298332963e1bbaf010046
ToppCellTCGA-Adrenal-Primary_Tumor-Pheochromocytoma-Pheochromocytoma|TCGA-Adrenal / Sample_Type by Project: Shred V9

VSTM2A GATA2 GATA3 ARHGEF17 SLC18A1 MAST1

1.19e-0519411661e1f4139ad584f493d75a9b7f1568eca4653c5a2
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_secretory|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MUC16 MUC5B PTK2 TMEM171 MUC4 FAM149A

1.23e-051951166e7230a849ea31e6eef9bc6f5468938499450582d
ToppCellTracheal-NucSeq|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations

ESRRG PTK2 MAGI2 NR3C2 UTY AGAP1

1.38e-05199116694b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCellBrain_organoid-organoid_Tanaka_cellReport-10w-Neuronal-Interneuron|10w / Sample Type, Dataset, Time_group, and Cell type.

PCLO VSTM2A GATA2 GATA3 CEP170 KIDINS220

1.41e-052001166f5c63ef52bd7a898cf009b8bf9b2f7f4890d1c9b
ToppCelldroplet-Bladder-nan-3m-Epithelial-nan|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AFF2 DZIP1L SMC5 ITGAM IKZF4

1.51e-051191165018162114bc22a9780fded5887f1f78211851700
ToppCell10x_3'_v3-blood_(10x_3'_v3)-hematologic-hematopoietic_progenitor-common_myeloid_progenitor|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

HSPG2 GATA2 DNAJC6 CD34 MROH7

2.98e-0513711656d90da42dcc06aa895f920218055068f3c76d57d
ToppCellThalamus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)|Thalamus / BrainAtlas - Mouse McCarroll V32

AFF2 ESRRG GATA3 SLC18A1 CACNA1I

4.30e-051481165afebb64365c94b9476494bffe7c364677f19c8cf
ToppCellThalamus-Neuronal-Inhibitory|Thalamus / BrainAtlas - Mouse McCarroll V32

AFF2 ESRRG GATA3 SLC18A1 CACNA1I

4.30e-0514811655f82e5ecacfd223020b8ee975c17d68c1fe6db38
ToppCellChildren_(3_yrs)-Immune-mast_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

KIF13B AFF2 SYTL2 GATA2 TMEM213

4.74e-051511165bbf735c6433c3fc2feedb24ed6f48c51d545fb60
ToppCellPND07-28-samps-Mesenchymal-Mesothelial|PND07-28-samps / Age Group, Lineage, Cell class and subclass

MUC16 DNAJC6 SBSN PCNX2 MAGI2

5.53e-051561165574f761962a7dd3308bd41fc529dd3ea1b8625f8
ToppCellPND07-28-samps-Mesenchymal-Mesothelial-Mesothelial|PND07-28-samps / Age Group, Lineage, Cell class and subclass

MUC16 DNAJC6 SBSN PCNX2 MAGI2

5.53e-051561165605d95a900e1443d3f6aae163ef2e893d3293203
ToppCell10x5'v1-week_17-19-Hematopoietic-HSC/MPP_and_pro|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

GOLGA8S ITGAD UMODL1 CD34 MN1

6.81e-051631165edca1d1a345109dbdeb7ee5464faefab1993fdb2
ToppCellIIF-Other-HSPC|IIF / Disease, Lineage and Cell Type

PCLO GATA2 ARHGEF17 CD34 MN1

6.81e-0516311651e0d38fbed38ac48478868a1480172a1a3f7c1b7
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_B-B_cell-B_c01-TCL1A|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

NLGN4Y ODAD1 GATA3 MUC5B NR3C2

7.85e-0516811659a8709d34865cfa668d8f3335dc34fc86fc32482
ToppCelltumor_Lymph_Node_/_Brain-T/NK_cells-Exhausted_Tfh|T/NK_cells / Location, Cell class and cell subclass

SLC25A18 MUC5B TNFSF8 MUC4 REV1

8.07e-051691165625788d86f0ceebcf2653a251db1f1a9f9746d29
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HSPG2 NLGN4Y ESRRG ARHGEF17 NOTCH2

8.30e-0517011655570c0e825bca77613bf0ebde620cf744fa1cb84
ToppCellE12.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

HSPG2 SGSM1 IRGQ FAM221B CD34

8.77e-0517211653b9be685fcd1634498a603b692f5ac6ddd0de176
ToppCellfacs-Marrow-T-cells-24m-Myeloid-CD4+_macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TEX2 ITGAD PTK2 CD68 SNTG2

9.01e-051731165ca3d2a9562734f76127e3e7d54c10b63e95141bb
ToppCellfacs-Marrow-T-cells-24m-Myeloid-macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TEX2 ITGAD PTK2 CD68 SNTG2

9.01e-05173116519a9e10885173d7712996be8660a3a5a7a9aa39f
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SGSM1 ESRRB ESRRG WNK1 AGAP1

9.01e-0517311654bc6d93716f093b460c8b047199db8cab5fea720
ToppCell10x5'-GI_small-bowel-Mast|GI_small-bowel / Manually curated celltypes from each tissue

HSPG2 AFF2 GATA2 ITGAM MROH7

9.26e-051741165e94c980b25edfd0e8598c416828801fcc00e8ead
ToppCell10x5'-GI_small-bowel-Mast-Mast_cells|GI_small-bowel / Manually curated celltypes from each tissue

HSPG2 AFF2 GATA2 ITGAM MROH7

9.26e-05174116505525bf0a2bde2be4f7c147b17a24530ce8819e0
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Degenerative_Distal_Convoluted_Tubule_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ESRRB ESRRG GATA3 WNK1 TMEM213

9.51e-051751165787ac1a12cda10af5c8830471702a4cbaf43e79e
ToppCellCOVID-19-kidney-Distal_Epi_Doublet_(PCT)|kidney / Disease (COVID-19 only), tissue and cell type

PCLO ESRRG SYTL2 NR3C2 FAM149A

9.77e-05176116536f77d878a53b30465b0dea8333a3865dba75613
ToppCellAdult-Epithelial-club_cell-D122|Adult / Lineage, Cell type, age group and donor

WWTR1 MAGI2 MUC4 UTY AGAP1

1.03e-04178116535a2e3ba98b6f857dbb79cf8ddb4846ddcda6c17
ToppCellSomatosensory_Cortex_(S1)|World / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NLGN4Y ESRRG VSTM2A NR3C2 UTY

1.06e-04179116582348bf56a4525b2f485696cab5b2ea6e96c2f91
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ESRRB ESRRG GATA3 WNK1 NR3C2

1.06e-041791165666072c0e8448dbaec1683d18368ec2502453f90
ToppCell5'-Adult-Appendix-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC25A18 VSTM2A ARHGEF17 MAGI2 NLGN4X

1.06e-041791165a1ea8daa0fe8900f5a04b555c77fe8ebdaa3908d
ToppCellwk_20-22-Epithelial-Proximal_epithelial-Pulmonary_neuroendocrine|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

CALHM1 VSTM2A GREB1L SLC18A1 MUC3A

1.09e-04180116557689ccbbd44c0e78e061edd87d3102c5f2dcc9a
ToppCellfacs-Kidney-nan-3m-Epithelial-kidney_collecting_duct_principal_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AFF2 ESRRB VSTM2A WNK1 TMEM213

1.09e-041801165fc5b9d0e3215652e490ca72d69f776e9725608b2
ToppCellfacs-Kidney-nan-3m-Epithelial-kidney_collecting_duct_principal_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AFF2 ESRRB VSTM2A WNK1 TMEM213

1.09e-0418011656763b22f2383931c747b37cd0ae2f60b08f64d90
ToppCellControl-Epithelial_cells-Airway_club|Control / group, cell type (main and fine annotations)

WWTR1 PTK2 MUC4 AGAP1 FAM149A

1.11e-041811165c755d23dd9aabc717dc73e2b3fa99a1f751e6507
ToppCellPBMC-Severe-Lymphocyte-T/NK-CD8+_T-MAIT-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SYTL2 GATA3 KMT2E TMEM171 AGAP1

1.14e-041821165f30e5a21b49f30b82e2b6f1fd2daefd805a40083
ToppCellCOVID-19-kidney-CD-IC-B|COVID-19 / Disease (COVID-19 only), tissue and cell type

KIF13B DLG5 ESRRG TMEM213 NR3C2

1.14e-041821165ee6a8c356bbbdae55e4ea858337e079491f9f4aa
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

KIF13B ESRRB ESRRG NLGN4X NR3C2

1.14e-041821165a8cc56f32efe180e8fb5d69dbe606a794b3db700
ToppCellPBMC-Severe-Lymphocyte-T/NK-CD8+_T-MAIT-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

SYTL2 GATA3 KMT2E TMEM171 AGAP1

1.14e-041821165cccac9f85825f4e310b86e37ee6320769a670501
ToppCellPBMC-Severe-Lymphocyte-T/NK-CD8+_T-MAIT|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SYTL2 GATA3 KMT2E TMEM171 AGAP1

1.14e-0418211651444cdc4522a70a40d697ccadf54cf26d327ade0
ToppCellPBMC-Severe-Lymphocyte-T/NK-CD8+_T-MAIT|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

SYTL2 GATA3 KMT2E TMEM171 AGAP1

1.14e-04182116549eced222e8f90c2b59bcc7d56b62c3e703fcce5
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

AFF2 NLGN4Y SYTL2 ARHGEF17 SNTG2

1.17e-0418311658a799807fbf24456a9811e0c64068187940a2f71
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-Epcam_____kidney_distal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM94 ESRRB MUC5B WNK1 TMEM213

1.17e-041831165f3728b1a51951c7349f77a3e4d2671ca3a8d2a44
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

AFF2 NLGN4Y SYTL2 ARHGEF17 SNTG2

1.20e-041841165689a8af81a79a4bb3123cfa01958c953eab5de98
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Degenerative_Connecting_Tubule_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SYTL2 GATA3 WNK1 TMEM213 NR3C2

1.20e-0418411659690d4290e70f9bda889754ffb30b0af1f7cb94b
ToppCellCiliated_cells-A-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

ODAD1 MUC16 MUC5B VWA3B MUC4

1.20e-04184116507c5a9633ccdcd18771e3230d6198a55c400afa6
ToppCellCOVID-19-Epithelial_cells-Airway_club|COVID-19 / group, cell type (main and fine annotations)

WWTR1 PTK2 MUC4 AGAP1 FAM149A

1.23e-041851165cfe6fd73d817e173fe803bc1683c291d9bcb8608
ToppCellCOVID-19-Endothelial_cells-Systemic_venous_endothelial_cells|COVID-19 / group, cell type (main and fine annotations)

HSPG2 WWTR1 PTK2 CD34 SNTG2

1.23e-041851165f5e14181f45c37d13ee9e017a4c8bc248c353676
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ESRRG GATA2 GATA3 TMEM213 NR3C2

1.23e-0418511653d73b3e0bceb192257e5cfbe64b7ccb379b6e22d
ToppCell(5)_Epithelial_cells-(5)_Glands_duct|(5)_Epithelial_cells / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)

ESRRG SYTL2 MUC16 MUC5B TMEM213

1.27e-041861165219b1aeca17503244fabbb780bca58f22c7c0f27
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ESRRG GATA2 GATA3 WNK1 NR3C2

1.27e-04186116508632045d499e61dd96ff29a5a9a208afe58dc58
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1-6_FGFR3_ETNPPL|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SLC25A18 TCF7L2 NHSL1 ZIC4 NOTCH2

1.30e-0418711654d2115a05ec36dd179ca1d4a525f2d4501aea557
ToppCellpdx-Tumor_cells-T5|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

RTTN ZMYND8 MAGI2 CACNA1I AGAP1

1.30e-0418711657e376831a11ee72ed87abcdac631ca46ae29c250
ToppCelldroplet-Lung-1m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HSPG2 ODAD1 NLGN3 FNDC1 FAM149A

1.30e-041871165ed7ab4cf4629d96dad5c74d536fc428d0a8d4eb9
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ESRRB ESRRG SYTL2 WWTR1 NR3C2

1.30e-041871165f124d2c699b717b7c02a1a70493f515b83dc2f4c
ToppCellCOVID-19-kidney-DCT|kidney / Disease (COVID-19 only), tissue and cell type

ESRRB ESRRG WNK1 TMEM213 NR3C2

1.33e-041881165df1fd0819d301679f3c9ea404e942e39095912eb
ToppCellCOVID-19-kidney-DCT|COVID-19 / Disease (COVID-19 only), tissue and cell type

ESRRB ESRRG GATA3 TMEM213 NR3C2

1.33e-0418811651d56cd409793f05cca20757ab26e91f1a1ee67b5
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SYTL2 MUC16 MUC5B TMEM213 MUC4

1.33e-0418811655901b276f2379abf486b8285957277e95f08464e
ToppCell5'-Adult-Appendix-Endothelial-blood_vessel_EC-arterial_capillary|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HSPG2 NHSL2 GATA2 CD34 KCTD15

1.33e-041881165a11b12f1857953bcdbfb5f25e127f2350c39567d
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ESRRG SYTL2 GATA3 WNK1 NR3C2

1.33e-0418811654154f4787483c7e076e87a187733a9f666742c3d
ToppCellhuman_hepatoblastoma-Tumor_cells-T5|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

RTTN ZMYND8 GATA3 IKZF4 AGAP1

1.33e-041881165b070a0667f1ee9b825b267b6c389b7c42fc436f9
ToppCelldroplet-Kidney-nan-3m-Epithelial-kidney_distal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM94 VSTM2A GATA3 WNK1 TMEM213

1.36e-041891165e127e3be626bc513e151d41812f0b7adb89d5da6
ToppCellCOVID-19-Heart-EC_(POSTN)|COVID-19 / Disease (COVID-19 only), tissue and cell type

HSPG2 NHSL2 WWTR1 CD34 SNTG2

1.36e-0418911657346c1112e2e155dbd71b6dbc80e680fd262a691
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ESRRG GATA2 GATA3 TMEM213 NR3C2

1.36e-041891165a9864873b19ab3e60acf11f288fa7275badc2e42
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ESRRG SYTL2 GATA3 WNK1 NR3C2

1.36e-04189116590aae7e806882bebfad78a78e9a16cf56af3ecd4
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ESRRB ESRRG GATA3 WNK1 NR3C2

1.36e-041891165975c0f079903ae36b0ffa54e86294d42ec7697de
ToppCelldroplet-Kidney-nan-3m-Epithelial-Epcam_____kidney_distal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM94 VSTM2A GATA3 WNK1 TMEM213

1.36e-041891165ff637ae0afdb1fdc67451be7e1e4fe575fbcfff4
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ESRRB ESRRG GATA3 WNK1 NR3C2

1.36e-0418911657eb8f5a951e80f1cfac4d7c9eb169f4eb100c917
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ESRRB ESRRG SYTL2 WWTR1 NR3C2

1.36e-041891165e32172ad09e93f6ac6ea2b92145b2b73003f7970
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KIF13B GATA2 GATA3 GREB1L NR3C2

1.36e-041891165532aaf02b364c5c4f58a2021c7c21d86df3875c9
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ESRRG GATA2 GATA3 TMEM213 NR3C2

1.40e-041901165b3bccf4dd95e986db3cee324a6737f5fcc22e8e5
ToppCellfacs-GAT-Fat-3m|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NHSL2 ITGAM WNK1 KIDINS220 CD68

1.40e-0419011651d92be1b41cff59e834a9d28868f554bd1f3e471
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Inner_Medullary_Collecting_Duct_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KIF13B ESRRG GATA3 GREB1L NR3C2

1.43e-0419111653e828cffa24ded19f591a7ed6c1fe88ad57fdcac
ToppCellfacs-Lung-EPCAM-24m-Epithelial-Neuroendocrine|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SGSM1 PCLO TMEM171 SLC18A1 GPR75

1.43e-041911165501d4f6ad389d9ac5051d4247b9bd3da96f713f9
ToppCellnucseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ODAD1 ESRRG MUC16 VWA3B MUC4

1.43e-041911165e417bf491f8b8d7838a61f7f4f6b1740ba97aa3f
ToppCellsevere_COVID-19-CD4+_T_naive|World / disease group, cell group and cell class (v2)

EDAR TNFSF8 SNTG2 CACNA1I NR3C2

1.43e-04191116555a282478488efd1561ea57a6f0218f55f711bb0
ToppCellnucseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ODAD1 ESRRG MUC16 VWA3B MUC4

1.43e-0419111659d31c8424d35bdc0c27188b68bfd0f731af3600b
ToppCellfacs-Lung-EPCAM-24m-Epithelial-lung_neuroendocrine_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SGSM1 PCLO TMEM171 SLC18A1 GPR75

1.43e-0419111658e06cc61eaff1796c2ce014074029408ba88d561
ToppCellnucseq-Epithelial-Epithelial_Airway|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ODAD1 ESRRG MUC16 VWA3B MUC4

1.43e-0419111651c528f72c9ef3ef3a850b05e4a9715190832270c
ToppCellCOVID-19-kidney-CNT|COVID-19 / Disease (COVID-19 only), tissue and cell type

ESRRG SYTL2 GATA3 TMEM213 NR3C2

1.47e-041921165760c6b9628de9693034b00c5025c5c4df94bb2e8
ToppCellEntopeduncular-Neuronal|Entopeduncular / BrainAtlas - Mouse McCarroll V32

SGSM1 VSTM2A USP29 MAST1 CACNA1I

1.47e-0419211654c35e5c28a40b439044797ba1f06cb7c36b2a8de
DiseaseAutism Spectrum Disorders

GPR50 SIN3A NLGN3 NLGN4X SNTG2

1.70e-05851105C1510586
Diseasecholangiocarcinoma (is_marker_for)

MUC16 MUC5B MUC3A MUC4

9.78e-05641104DOID:4947 (is_marker_for)
Diseasehearing loss

TRIOBP MAST2 ITGAM PTK2

1.17e-04671104EFO_0004238
DiseaseGlycosuria

TCF7L2 ITGAD

2.86e-0471102HP_0003076
Diseasepseudohypoaldosteronism (is_implicated_in)

WNK1 NR3C2

3.80e-0481102DOID:4479 (is_implicated_in)
Diseasefemale breast cancer (is_implicated_in)

CHEK2 MAST1

3.80e-0481102DOID:0050671 (is_implicated_in)
DiseaseNeoplasm of uncertain or unknown behavior of breast

GATA3 CHEK2 NOTCH2

4.85e-04411103C0496956
DiseaseBreast adenocarcinoma

GATA3 CHEK2 NOTCH2

4.85e-04411103C0858252
Diseaseobsolete_red blood cell distribution width

TPP2 FOXK2 ASAH2 ITGAD WNK1 HCP5 PTK2 CEP170 TMEM171 CHEK2 MAST1 CD68 MUC4 AGAP1

4.88e-04134711014EFO_0005192
Diseaseautistic disorder (is_implicated_in)

KMT2E NLGN3 NLGN4X

5.21e-04421103DOID:12849 (is_implicated_in)
Diseaseheart rate response to exercise

TCF7L2 SCN10A MUC3A

5.58e-04431103EFO_0009184
DiseasePseudohypoaldosteronism, Type I

WNK1 NR3C2

6.08e-04101102C0268436
DiseasePseudohypoaldosteronism

WNK1 NR3C2

6.08e-04101102C0033805
Diseaseotitis media (is_marker_for)

MUC5B MUC4

6.08e-04101102DOID:10754 (is_marker_for)
DiseaseHyperpotassemia and Hypertension, Familial

WNK1 NR3C2

6.08e-04101102C2713447
DiseasePseudohypoaldosteronism, Type I, Autosomal Recessive

WNK1 NR3C2

6.08e-04101102C1449843
DiseasePseudohypoaldosteronism, Type II

WNK1 NR3C2

6.08e-04101102C1449844
DiseasePseudohypoaldosteronism, Type I, Autosomal Dominant

WNK1 NR3C2

6.08e-04101102C1449842
Diseasemyeloid leukemia (is_implicated_in)

GATA2 MN1

1.05e-03131102DOID:8692 (is_implicated_in)
Diseasehyperglycemia (is_marker_for)

HSPG2 ITGAM

1.05e-03131102DOID:4195 (is_marker_for)
Diseasefactor VII activating protease measurement

TCF7L2 SGSM1 ZMYND8

1.15e-03551103EFO_0009368
DiseaseGastro-enteropancreatic neuroendocrine tumor

GATA3 NOTCH2

1.40e-03151102C2930967
Diseaseadverse effect, response to xenobiotic stimulus

ESRRG MAGI2 VWA3B

1.41e-03591103EFO_0009658, GO_0009410
Diseasebreast carcinoma

TCF7L2 FOXK2 ESRRG SIN3A MAST2 CD34 CHEK2 MAST1 MN1 NOTCH2 PCNT

1.50e-03101911011EFO_0000305
Diseasepancreatic ductal carcinoma (is_marker_for)

MUC5B MUC3A MUC4

1.55e-03611103DOID:3587 (is_marker_for)
Disease2-hydroxyglutarate measurement

ESRRG PCNT

1.60e-03161102EFO_0021506
DiseaseBipolar Disorder

TCF7L2 GPR50 PCLO ITGAM MAGI2 SLC18A1 PCNT

2.10e-034771107C0005586
Diseaseautism spectrum disorder (implicated_via_orthology)

NLGN4Y NLGN3 NLGN4X NR3C2

2.56e-031521104DOID:0060041 (implicated_via_orthology)
DiseaseCraniofacial Abnormalities

HSPG2 GATA2 SIN3A MNT

2.81e-031561104C0376634
Diseasecortical thickness

HSPG2 TCF7L2 TRIOBP MAST2 NHSL1 ZIC4 PHYH UMODL1 CD68 AGAP1 AGAP3

2.97e-03111311011EFO_0004840
DiseaseAutistic Disorder

KMT2E NLGN3 NLGN4X SNTG2 AGAP1

3.00e-032611105C0004352
Diseasegestational diabetes

IL15RA TCF7L2

3.31e-03231102EFO_0004593
Diseasecancer (implicated_via_orthology)

ESRRB ESRRG WWTR1 SIN3A NOTCH2

3.36e-032681105DOID:162 (implicated_via_orthology)
Diseasealcohol drinking

ESRRG KMT2E MNT

3.48e-03811103EFO_0004329
DiseaseHodgkins lymphoma

GATA3 HCP5 CACNA1I

3.60e-03821103EFO_0000183

Protein segments in the cluster

PeptideGeneStartEntry
STVHHLHSAPGNAST

UMODL1

211

Q5DID0
GTGAPHSASSASLHS

AGAP3

461

Q96P47
DTPSSHITGAGHASF

CEP170

266

Q5SW79
LSGSGTHSHGNQSTT

AMMECR1L

26

Q6DCA0
THSHGNQSTTVPGSS

AMMECR1L

31

Q6DCA0
HISPNSGNVTSASGS

AGAP1

436

Q9UPQ3
QTHLPSGASSGTGSA

BAG6

91

P46379
VSHTTTSGILNSAPH

BAZ2A

61

Q9UIF9
HTAGHSEQSTFSIPG

AFF2

376

P51816
GHTHGTLATAPASAA

CALHM1

261

Q8IU99
GHSADSSRQSGTPHA

FLG

996

P20930
HTTPQGRSDASHGQS

FLG

1521

P20930
THEQSESAHGRTGPS

FLG

1771

P20930
HSGIQSRGSPHSSSS

FLG

3941

P20930
QSHGSSACSQPHGSV

CHEK2

11

O96017
HTLAATTGTTQHSTP

MUC5B

2236

Q9HC84
LGTTHITEPSTGTSH

MUC5B

4036

Q9HC84
IPGSSYGISLHSSTH

MROH7

301

Q68CQ1
TVSVLHGTHSGPSYT

HSPG2

2131

P98160
STHTSPSQSPNSVHG

RBSN

211

Q9H1K0
SIHETATSGGCHSPG

GOLGA8S

41

H3BPF8
LSSSSAQTNHHGPGT

ARHGEF17

671

Q96PE2
TTGTTSHGPTTATHN

CD68

66

P34810
TATHNPTTTSHGNVT

CD68

76

P34810
HGNVTVHPTSNSTAT

CD68

86

P34810
TATHSPATTSHGNAT

CD68

106

P34810
HGNATVHPTSNSTAT

CD68

116

P34810
PPTRQSHGSHGSSLT

DZIP1L

571

Q8IYY4
SHGSHGSSLTQVSAP

DZIP1L

576

Q8IYY4
GGTHSTVSQGFPHSE

MUC16

5591

Q8WXI7
AHTEAVHPSTNTGGT

MUC16

7761

Q8WXI7
SGTHSTASPGFSHSE

MUC16

8521

Q8WXI7
GHTTPLHVTDASSAS

MUC4

1356

Q99102
TNASSLSTGHATPLH

MUC4

1636

Q99102
SASTGHATPLHVTDA

MUC4

2296

Q99102
HVTDASSASTGHATP

MUC4

2306

Q99102
STGHATPLHVTDASS

MUC4

2346

Q99102
TGHATHLPVTGLSSA

MUC4

2411

Q99102
TSSASTGHANPLHVT

MUC4

3046

Q99102
TDASSASTGHATPLH

MUC4

3316

Q99102
SHHHIVSPGSGSAGS

NOTCH2

2226

Q04721
TTHGQTGDTSGHSQS

FLG2

1846

Q5D862
SEGPSGVSHTHSGHT

FLG2

1961

Q5D862
EASPTHSGHTHSQAG

FLG2

2191

Q5D862
SGVRSSESSPNHSLH

KIDINS220

1586

Q9ULH0
SRSHSPAHASNVGSP

NR3C2

246

P08235
STSATAASHTRHPEG

MAGEB10

71

Q96LZ2
ENGRSPGSVSTHHSS

MAGI2

871

Q86UL8
GTTEISSHESSHGTP

IL15RA

161

Q13261
HSVTTNLSSTPFGHG

NEDD1

146

Q8NHV4
SFSSSGSHTPTGAHT

FAM149A

231

A5PLN7
HAGVLSAHSSGAQTP

FOXK2

376

Q01167
DNVILSGTHTHSGPA

ASAH2

186

Q9NR71
GTSGSSTLSPFQHAH

EDAR

161

Q9UNE0
PITGHHVSAGSHSKS

GPR50

476

Q13585
SAAQAGSHATHPGTS

NHSL1

1251

Q5SYE7
HSSPGSSKSSSEGHL

PCLO

4876

Q9Y6V0
SRGQSITSHHSSGPL

PCNX2

146

A6NKB5
TTPTTITHHSVGSTG

MUC3A

446

Q02505
SDSTAHTAQPGHQLG

FAM221B

186

A6H8Z2
SSHLDPAGTHSTLQG

DLG5

1441

Q8TDM6
AVTPGSHIHSQTAGH

KMT2E

1661

Q8IZD2
GGSTVIAHTATTHAS

MNT

436

Q99583
IGSVSHHVVSGPSSQ

GCN1

366

Q92616
SGSLSHSEPSHGLAD

GREB1L

791

Q9C091
TFGGLSSSTGHLPSH

ODAD1

561

Q96M63
SSSTGHLPSHITHGD

ODAD1

566

Q96M63
SSPTSVLGGSRHQSH

PCNT

2191

O95613
SAGHQHCGQSSSTPI

GPR75

461

O95800
SSSHPLVSGHILSNS

HCP5

96

Q6MZN7
LPGHTVGSSHTTQSF

MAST1

1221

Q9Y2H9
TGTDLGTNTSPQHHF

MFSD14A

406

Q96MC6
HGASESGISPSHSQR

ITGAD

556

Q13349
AAGFNSTGLPHSHST

NLGN3

831

Q9NZ94
GQNSTNLPHGHSTTR

NLGN4Y

801

Q8NFZ3
GSGSSVASLTPTAAH

GATA2

151

P23769
ASSSSLSGGHASPHL

GATA3

136

P23771
TALGGASSSTHHPIT

GATA3

206

P23771
HETGSNNPLGITSHS

MT-CYB

201

P00156
HSQGGSSVHPRTLQT

CR1

2016

P17927
LAVHHQGSASAPSTS

SLC25A18

136

Q9H1K4
ASASPAHHASTQGTS

FNDC1

616

Q4ZHG4
DSVNHHSPGGSSDAS

ESRRG

51

P62508
RAHQRSHSSGGSTSP

CACNA1I

2081

Q9P0X4
ATSPTGSSHGTPTHQ

DNAJC6

656

O75061
AVHSVGGNSSQSSSP

MAST2

1286

Q6P0Q8
STTFGSHHLPNRVGS

FAM102B

336

Q5T8I3
GIDALSHHSPSGSSD

ESRRB

26

O95718
PHSSNGHSPQDTSTS

ZMYND8

26

Q9ULU4
SGSSSHQGGATTTPL

SBSN

551

Q6UWP8
GQNSTNLPHGHSTTR

NLGN4X

801

Q8N0W4
TLGSTSLHPVSQHGN

CD34

66

P28906
TGHLRTHSVSSPTVG

IKZF4

231

Q9H2S9
HTGTATTAAAASHPT

IRGQ

281

Q8WZA9
SSVSNALPVSGSHLG

PRDM4

21

Q9UKN5
VAHPTSGTISSASFH

PHYH

26

O14832
ASFHGLPSSSGSDSH

MN1

201

Q10571
GIQHASHGTASAASP

GARIN3

236

Q8TC56
NGSSVSSPIQLHHGD

KIF13B

516

Q9NQT8
RGTHHSQNPSPGSSS

RTTN

296

Q86VV8
TSGSFPINGLHSHSE

SYTL2

411

Q9HCH5
NSVTSLNSPHSGLHT

UTY

786

O14607
QHHVGNSSPTSTSPS

RBM7

101

Q9Y580
QSPASHRNPTGAHSS

TNP2

51

Q05952
GAHSSSGHQSQSPNT

TNP2

61

Q05952
SSGPTSHTQASLSHE

TNRC6C

1446

Q9HCJ0
DQGHSNSPAGSVAHS

NHSL2

296

Q5HYW2
NHTPNSSTKTHLGTG

PTK2

11

Q05397
SHAGTTQCSIHSPSS

GAS8-AS1

101

O95177
SGSHGPAIAAVHSSH

SIN3A

71

Q96ST3
SGLHLNGNSSTTAPS

SNTG2

186

Q9NY99
HGTSGSGISPSHSQR

ITGAM

556

P11215
NLPSRATSSSHNPGH

TRIOBP

971

Q9H2D6
ATSSSHNPGHQSTSR

TRIOBP

976

Q9H2D6
HNPGHQSTSRTSSPV

TRIOBP

981

Q9H2D6
HVPAGSVASHLGTTS

TNFSF8

21

P32971
TTHSSSLIAGHTGPV

UBN2

826

Q6ZU65
PSSIHGSANQRTHST

VSTM2A

181

Q8TAG5
SPDTHSGGHSSSSNS

RBMXL3

526

Q8N7X1
GAHHSTVQGPSSTKS

REV1

311

Q9UBZ9
GGTSPTLSHSSSLLH

TMEM94

391

Q12767
HGRSKHPSGSNVSFS

TMEM94

506

Q12767
ERPSGSSLHTHGSTG

KCTD15

6

Q96SI1
THSSPALSQGHVTGS

PSD2

746

Q9BQI7
GIDTTSLHSHNGSPL

SCN10A

436

Q9Y5Y9
QPSTSSLHSHSSLAG

TCF7L2

591

Q9NQB0
SIVTSGGAHGTHVAS

TPP2

256

P29144
SHTPTPGTQGHSSGT

UBL7

286

Q96S82
SSSVSSGHLGALNHS

XRN1

1201

Q8IZH2
ISVVSHIGSSPNSGH

USP29

826

Q9HBJ7
SIPFHSSNSGSTGHL

NFATC3

851

Q12968
SSNSGSTGHLLAHTP

NFATC3

856

Q12968
DSGHPSSHNFSSGLS

SGSM1

766

Q2NKQ1
ISGTNSSSEASHTPH

TMEM171

281

Q8WVE6
HDLHLTSPSSTGSGQ

UNKL

321

Q9H9P5
KESSSSSGHHGPQLT

ZIC4

21

Q8N9L1
SSGHHGPQLTAASSP

ZIC4

26

Q8N9L1
SSTSIFTHPSSSGGH

ZSWIM8

1256

A7E2V4
PSDSDGSSHGISSHG

VWA3B

1221

Q502W6
GSAPISAASATSLGH

WNK1

2301

Q9H4A3
SPSGHLTHSRSSSKG

TEX2

736

Q8IWB9
LTPHHQSGGERSVST

SMC5

986

Q8IY18
SSNSSSLTAHHPDPG

TMEM213

31

A2RRL7
VHSGSSGGPLFSNHS

TYSND1

476

Q2T9J0
HSRQSSTDSSGGHPG

WWTR1

61

Q9GZV5
EVNSSLHLGHAGSSP

SLC18A1

56

P54219
SIHETATSGGCHSPG

GOLGA8CP

41

A6NN73