Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
DomainHECW_N

HECW1 HECW2

3.22e-062342IPR032348
DomainHECW_N

HECW1 HECW2

3.22e-062342PF16562
DomainSOHO

SORBS1 SORBS2

9.64e-063342PS50831
DomainSorb

SORBS1 SORBS2

9.64e-063342SM00459
DomainSorb

SORBS1 SORBS2

9.64e-063342PF02208
DomainSoHo_dom

SORBS1 SORBS2

9.64e-063342IPR003127
DomainSer/Thr_kinase_AS

DAPK1 SRPK1 SRPK3 ARAF KSR2

4.38e-04357345IPR008271
DomainS_TKc

DAPK1 SRPK1 SRPK3 ARAF KSR2

4.49e-04359345SM00220
DomainPROTEIN_KINASE_ST

DAPK1 SRPK1 SRPK3 ARAF KSR2

4.66e-04362345PS00108
DomainFibrinogen_CS

ANGPTL6 ANGPTL1

5.39e-0419342IPR020837
DomainPkinase

DAPK1 SRPK1 SRPK3 ARAF KSR2

5.88e-04381345PF00069
Domain-

CLVS1 MCF2L2

7.95e-04233423.40.525.10
Domain-

ANGPTL6 ANGPTL1

8.66e-04243424.10.530.10
DomainFibrinogen_a/b/g_C_2

ANGPTL6 ANGPTL1

8.66e-0424342IPR014715
DomainSEC14

CLVS1 MCF2L2

9.40e-0425342SM00516
DomainHECT

HECW1 HECW2

1.10e-0327342PF00632
DomainHECTc

HECW1 HECW2

1.10e-0327342SM00119
DomainHECT_dom

HECW1 HECW2

1.10e-0327342IPR000569
DomainHECT

HECW1 HECW2

1.10e-0327342PS50237
DomainFibrinogen_C

ANGPTL6 ANGPTL1

1.10e-0327342PF00147
DomainCRAL_TRIO

CLVS1 MCF2L2

1.10e-0327342PS50191
DomainCRAL-TRIO_dom

CLVS1 MCF2L2

1.18e-0328342IPR001251
DomainFBG

ANGPTL6 ANGPTL1

1.27e-0329342SM00186
Domain-

ANGPTL6 ANGPTL1

1.36e-03303423.90.215.10
DomainFibrinogen_a/b/g_C_1

ANGPTL6 ANGPTL1

1.36e-0330342IPR014716
DomainFibrinogen_a/b/g_C_dom

ANGPTL6 ANGPTL1

1.54e-0332342IPR002181
DomainFIBRINOGEN_C_2

ANGPTL6 ANGPTL1

1.54e-0332342PS51406
DomainFIBRINOGEN_C_1

ANGPTL6 ANGPTL1

1.54e-0332342PS00514
DomainC2

HECW1 SYTL4 HECW2

1.72e-03131343PF00168
DomainProt_kinase_dom

DAPK1 SRPK1 SRPK3 ARAF KSR2

1.79e-03489345IPR000719
DomainPROTEIN_KINASE_DOM

DAPK1 SRPK1 SRPK3 ARAF KSR2

1.86e-03493345PS50011
DomainC2

HECW1 SYTL4 HECW2

1.96e-03137343SM00239
DomainC2

HECW1 SYTL4 HECW2

2.17e-03142343PS50004
Domain-

HECW1 SYTL4 HECW2

2.44e-031483432.60.40.150
DomainKinase-like_dom

DAPK1 SRPK1 SRPK3 ARAF KSR2

2.80e-03542345IPR011009
DomainC2_dom

HECW1 SYTL4 HECW2

3.26e-03164343IPR000008
DomainWW

HECW1 HECW2

3.30e-0347342PF00397
DomainWW

HECW1 HECW2

3.44e-0348342SM00456
DomainWW_DOMAIN_2

HECW1 HECW2

3.88e-0351342PS50020
DomainWW_DOMAIN_1

HECW1 HECW2

3.88e-0351342PS01159
DomainWW_dom

HECW1 HECW2

4.03e-0352342IPR001202
DomainProtein_kinase_ATP_BS

DAPK1 SRPK1 SRPK3 ARAF

4.78e-03379344IPR017441
DomainC1_1

ARAF KSR2

4.82e-0357342PF00130
DomainZF_DAG_PE_1

ARAF KSR2

6.04e-0364342PS00479
DomainZF_DAG_PE_2

ARAF KSR2

6.04e-0364342PS50081
DomainC1

ARAF KSR2

6.23e-0365342SM00109
DomainPE/DAG-bd

ARAF KSR2

6.41e-0366342IPR002219
Domain-

PCSK4 NCCRP1

7.80e-03733422.60.120.260
DomainSH3_9

SORBS1 SORBS2

8.86e-0378342PF14604
DomainPROTEIN_KINASE_ATP

DAPK1 SRPK1 SRPK3 ARAF

9.32e-03459344PS00107
DomainSH3_2

SORBS1 SORBS2

1.07e-0286342IPR011511
DomainSH3_2

SORBS1 SORBS2

1.07e-0286342PF07653
Pubmed

Cytoplasmic YAP1-mediated ESCRT-III assembly promotes autophagic cell death and is ubiquitinated by NEDD4L in breast cancer.

HECW1 SYTL4 HECW2

1.12e-062134337005481
Pubmed

[A novel adaptor protein family regulating cytoskeletal organization and signal transduction--Vinexin, CAP/ponsin, ArgBP2].

SORBS1 SORBS2

2.78e-06334212510380
Pubmed

The sorbin homology domain: a motif for the targeting of proteins to lipid rafts.

SORBS1 SORBS2

5.56e-06434211481476
Pubmed

Sorbs1 and -2 Interact with CrkL and Are Required for Acetylcholine Receptor Cluster Formation.

SORBS1 SORBS2

5.56e-06434226527617
Pubmed

NEDL1, a novel ubiquitin-protein isopeptide ligase for dishevelled-1, targets mutant superoxide dismutase-1.

HECW1 HECW2

9.26e-06534214684739
Pubmed

Recruitment of Pyk2 and Cbl to lipid rafts mediates signals important for actin reorganization in growing neurites.

SORBS1 SORBS2

1.94e-05734215128873
Pubmed

Angiopoietin-like gene expression in the mouse uterus during implantation and in response to steroids.

ANGPTL6 ANGPTL1

1.94e-05734222350948
Pubmed

Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition.

SRPK1 SRPK3 ARAF TRIM41 KSR2

2.94e-0537234522939624
Pubmed

NEDL2 is an essential regulator of enteric neural development and GDNF/Ret signaling.

HECW1 HECW2

5.07e-051134225555806
Pubmed

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

CCDC85C SORBS1 SORBS2 ARAF TRIM41

6.94e-0544634524255178
Pubmed

A novel isoform of Vinexin, Vinexin gamma, regulates Sox9 gene expression through activation of MAPK cascade in mouse fetal gonad.

SORBS1 SORBS2

8.38e-051434215836771
Pubmed

NEDL2 regulates enteric nervous system and kidney development in its Nedd8 ligase activity-dependent manner.

HECW1 HECW2

8.38e-051434227119228
Pubmed

Systematic analysis of candidate genes for Alzheimer's disease in a French, genome-wide association study.

DAPK1 CH25H

1.25e-041734220413850
Pubmed

Differential effects of Tat proteins derived from HIV-1 subtypes B and recombinant CRF02_AG on human brain microvascular endothelial cells: implications for blood-brain barrier dysfunction.

SORBS1 ANGPTL1 CH25H

1.49e-0410534324667918
Pubmed

SCFFBXL¹⁵ regulates BMP signalling by directing the degradation of HECT-type ubiquitin ligase Smurf1.

HECW1 HECW2

1.57e-041934221572392
Pubmed

Expanding the substantial interactome of NEMO using protein microarrays.

DAPK1 SRPK1 TRIM41

1.67e-0410934320098747
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

CCDC85C SRPK3 SORBS1 SORBS2 AFTPH ARAF

1.68e-0486134636931259
Pubmed

The E3 ubiquitin ligase FBXL6 controls the quality of newly synthesized mitochondrial ribosomal proteins.

CCDC85C RANBP6 SRPK1 SORBS1 SYTL4

1.80e-0454734537267103
Pubmed

Assessment of Alzheimer's disease case-control associations using family-based methods.

DAPK1 CH25H

2.12e-042234218830724
Pubmed

Identification of preferred protein interactions by phage-display of the human Src homology-3 proteome.

SORBS1 SORBS2

2.74e-042534216374509
Pubmed

Intermediate phenotypes identify divergent pathways to Alzheimer's disease.

DAPK1 CH25H

2.74e-042534220574532
Pubmed

Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.

SORBS1 SORBS2 MCF2L2

2.81e-0413034312421765
Pubmed

System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes.

HECW1 HECW2

2.97e-042634226949039
Pubmed

Association of CR1, CLU and PICALM with Alzheimer's disease in a cohort of clinically characterized and neuropathologically verified individuals.

DAPK1 CH25H

3.45e-042834220534741
Pubmed

Centronuclear myopathy in mice lacking a novel muscle-specific protein kinase transcriptionally regulated by MEF2.

SRPK1 SRPK3

4.24e-043134216140986
Pubmed

HIV-1 Vpr degrades the HLTF DNA translocase in T cells and macrophages.

MISP SORBS2

4.52e-043234227114546
Pubmed

Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.

SRPK1 HECW1 TENT4A PCSK4 HECW2

6.75e-0473034534857952
Pubmed

Competitive binding of E3 ligases TRIM26 and WWP2 controls SOX2 in glioblastoma.

SRPK1 TBL3 NCCRP1 RYR1 KSR2

6.84e-0473234534732716
Pubmed

Abnormal Mammary Development in 129:STAT1-Null Mice is Stroma-Dependent.

CCR3 CLCA1

8.55e-044434226075897
GeneFamilyMitogen-activated protein kinase kinase kinases|RAF family

ARAF KSR2

1.28e-0552121157
GeneFamilyFibrinogen C domain containing|Angiopoietin like

ANGPTL6 ANGPTL1

3.58e-058212905
GeneFamilyFibrinogen C domain containing

ANGPTL6 ANGPTL1

3.79e-0425212554
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

HECW1 HECW2

7.90e-0436212823
ToppCellfacs-Lung-nan-3m-Endothelial-vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SORBS2 CLCA1 SYTL4 HECW2 CH25H CA8

3.28e-0917034667d7e1da3ebd2d14cb2e67799e94d655027ed5c4
ToppCellfacs-Lung-nan-3m-Endothelial-Vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SORBS2 CLCA1 SYTL4 HECW2 CH25H CA8

3.28e-091703468e1f757ed62218c0fb6525f49d142dd2cd29acf9
ToppCell(5)_Epithelial_cells-(5)_Glands_duct|(5)_Epithelial_cells / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)

DAPK1 MISP SORBS2 CA8

1.19e-05186344219b1aeca17503244fabbb780bca58f22c7c0f27
ToppCelldroplet-Lung-LUNG-30m-Endothelial-Vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLCA1 HECW2 CH25H CA8

1.19e-0518634441f1674afc17661eccaa779cdeb663db5e45685d
ToppCelldroplet-Lung-LUNG-30m-Endothelial-vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLCA1 HECW2 CH25H CA8

1.19e-05186344aa006650cf21a2c51dfe1091681f67fdad939107
ToppCelldroplet-Lung-nan-18m-Endothelial-vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLCA1 HECW2 CH25H CA8

1.35e-0519234445929c757d873fe314cc36d27abd265414635490
ToppCelldroplet-Lung-nan-18m-Endothelial-Vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLCA1 HECW2 CH25H CA8

1.35e-05192344beb336d3479821bdab7e8e2c58812f155e44e9a2
ToppCellTransverse-(5)_Dendritic_cell-(53)_Lymphoid_DC|Transverse / shred on region, Cell_type, and subtype

DAPK1 ANGPTL6 NCCRP1 RYR1

1.49e-0519734415b87fd3906d7388c271d30d0c64b1bcc490801c
ToppCellTransverse-Dendritic_cell-Lymphoid_DC|Transverse / Region, Cell class and subclass

DAPK1 ANGPTL6 NCCRP1 RYR1

1.49e-05197344a58af0ea82f76f2a7abac1f62629ff20d552fc63
ToppCellPBMC-Control-Lymphocyte-T/NK-CD4+_T-Treg-Treg_2|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SRPK1 PCSK4 MCF2L2

1.32e-041303430f9d3e6297f48ae14d24ac997d8d3a94f337d4d4
ToppCellPBMC-Control-Lymphocyte-T/NK-CD4+_T-Treg-Treg_2|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

SRPK1 PCSK4 MCF2L2

1.32e-04130343fc68a648161dd314d9ee6612fd039cb12171b8c6
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligoastrocytoma-9|TCGA-Brain / Sample_Type by Project: Shred V9

SORBS1 SYTL4 RYR1

1.44e-041343432647453f44b0e0a8f27ef9bba750e99eb40efc8b
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Degenerative_Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RANBP6 CCR3 RSPH1

1.79e-04144343cf9f049ab6cd80521598124f057c2debdde24788
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_104|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RANBP6 CCR3 RSPH1

1.79e-0414434341eaeca54b3c39de417597267cbdb1f195dd885a
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TBL3 NCCRP1 CA8

1.86e-04146343ec1f793409d1a81c0f9323eb3c82ffe01dae0e44
ToppCellsevere_influenza-Treg|World / disease group, cell group and cell class (v2)

HECW1 MCF2L2 CH25H

1.98e-041493432a3a00cdf604c8f3f3863df0ddb06938549bf86d
ToppCellCOVID_non-vent-Myeloid-Monocytic-SC_&_Eosinophil|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

CCR3 SYTL4 CA8

2.35e-041583430d4fe87fc7901dd5f9c004e91708a03cafdb4ad9
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_2-Inh_L1-6_PVALB_SCUBE3_(Chandelier_1)|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NCCRP1 RYR1 CA8

2.44e-04160343e8b02b9eb86d92ab691e576e3860247c238254f7
ToppCellLPS-IL1RA-Myeloid-Dendritic_cells-pDC|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CDH23 SRPK3 CCR3

2.44e-04160343dee756a2dc9725520d439e7273c489c2284015d8
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_II-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ANGPTL6 MCF2L2 CH25H

2.57e-04163343a6e272e043859858084b8d4d96fa4ff9e6eca454
ToppCellfacs-Marrow-Granulocytes-24m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SRPK3 RYR1 CA8

2.57e-041633438509b87748ec460992ae6cedbb155e1c6f6e2e48
ToppCellfacs-Marrow-Granulocytes-24m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SRPK3 RYR1 CA8

2.57e-04163343e04de78a52cc886623689a913f7852200a77605b
ToppCellLPS_only-Epithelial_airway|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CLCA1 RSPH1 NCCRP1

2.62e-0416434356e6934e6c7503a300d7be06762d45a1d6f1ae0f
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma-9|TCGA-Brain / Sample_Type by Project: Shred V9

SORBS1 SYTL4 RYR1

2.76e-04167343013971700e80b71e4b8c79b8fff0d8beeac295c3
ToppCell5'-Adult-Appendix-Hematopoietic-Myeloid-Lymphoid_DC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DAPK1 ANGPTL6 NCCRP1

2.76e-041673438b223333c0c7a85b5a1af6f2f5b12ee0d94357f6
ToppCellE17.5-Mesenchymal-mesenchymal_fibroblast-tracheal_fibroblast|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SORBS2 PCSK4 ANGPTL1

2.86e-0416934358e22f9119240664515fe91ca53812611a8f17d6
ToppCell5'-Adult-LargeIntestine-Epithelial-goblet-Goblet_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CLCA1 KSR2 CA8

2.96e-0417134348125d825ca2d7ef34564250f5b47d2a579e03c9
ToppCellPND28-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CLCA1 CH25H CA8

3.01e-04172343fc092a0631555d79e00ef9890cbd806e15bca2d4
ToppCellPND28-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CLCA1 CH25H CA8

3.01e-04172343745725bd10c82017d678463b8fef0d2dcf09a8fd
ToppCelldroplet-Fat-SCAT-30m-Endothelial-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDH23 SORBS1 CA8

3.06e-04173343eb58b0189e71e38d4f4f1cf544a82cde8d1c86bc
ToppCellfacs-Marrow-Granulocytes-3m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCR3 SYTL4 HECW2

3.17e-041753431b35acece23712ab7e3f92d9d68266efd38b3ef5
ToppCellfacs-Marrow-Granulocytes-3m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCR3 SYTL4 HECW2

3.17e-04175343a9f88054e2c28d604c65ed785f63021aadb7f4c8
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal-mesothelial_cell-Mesothelium_(RGS5+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DAPK1 SORBS2 NCCRP1

3.17e-04175343f5451c29c487b998778e50349b3d774d5e20fd28
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_2-Inh_L3-6_PVALB_MFI2_(Chandelier_2)|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SRPK3 RYR1 CA8

3.27e-041773434d67e24653caa318039870114849426ff2582e0c
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_2-Inh_L3-6_PVALB_MFI2_(Chandelier_2)|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SRPK3 RYR1 CA8

3.33e-04178343c982a73955c9c193bcab21d60d453afcc09cd586
ToppCellfacs-Lung-Endomucin-3m-Endothelial-Vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SORBS2 CH25H CA8

3.33e-041783435cc182e6faa7ba5b88378d2c953be29bbbb95a7e
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ANGPTL1 NCCRP1 CA8

3.33e-041783433d6d03bc57062f74ba19fc675dd36b12b6c7115d
ToppCellfacs-Lung-18m-Endothelial-venous_endothelial-vein_endothelial_cell-vein_endothelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SORBS2 CH25H CA8

3.33e-04178343ccd37575b60102f5e647c01546e8ff8fec638bd7
ToppCellfacs-Lung-Endomucin-3m-Endothelial-vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SORBS2 CH25H CA8

3.33e-04178343f9a16bc3f09c35c7d30e3809da024bc2dcf746ed
ToppCellfacs-Lung-18m-Endothelial-venous_endothelial|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SORBS2 CH25H CA8

3.33e-0417834387b04753650e45f12299c8456fb980d6c0d5961c
ToppCellfacs-Lung-18m-Endothelial-venous_endothelial-vein_endothelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SORBS2 CH25H CA8

3.33e-04178343ebfae386a518ea33911ba3ff40464c94d18ef695
ToppCell343B-Lymphocytic-CD4_T-cell-Treg_cell_4|343B / Donor, Lineage, Cell class and subclass (all cells)

AFTPH RYR1 TRMT12

3.38e-04179343c09c3eed43d1aa3b7aa8f3021e6f2737840cde16
ToppCellrenal_papilla_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

KSR2 MCF2L2 CA8

3.44e-0418034349829e833fe6d2431cfd2e8f378c2aaa3b2b46a4
ToppCelldroplet-Limb_Muscle-Pre-Sort|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SORBS1 SORBS2 CH25H

3.44e-04180343af2bafcd1b2082629de3ea336711add01565c4c4
ToppCellFetal_29-31_weeks-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CCDC85C SORBS1 HECW2

3.44e-04180343d8ef44710a77ad0fc03243428e5e1dc4d41200cb
ToppCelldroplet-Marrow-nan-21m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCR3 HECW2 CA8

3.44e-0418034341e8155cc7b3dac9d496e4077845ca6af1591a5c
ToppCelldroplet-Limb_Muscle-Pre-Sort-18m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SORBS1 SORBS2 CH25H

3.44e-04180343f29a995cf6e1a1836ed68b73258d9370bf3d4434
ToppCellfacs-Lung-3m-Endothelial-venous_endothelial-vein_endothelial_cell-vein_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SORBS2 CH25H CA8

3.50e-0418134372c28baf4fd417ff4a7068603830d55074960144
ToppCellfacs-Lung-3m-Endothelial-venous_endothelial-vein_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SORBS2 CH25H CA8

3.50e-041813432ac4d3e8987d5a009d7908d8787e18165826202a
ToppCellfacs-Lung-3m-Endothelial-venous_endothelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SORBS2 CH25H CA8

3.50e-041813432628c7ac345eaaeecf8e34617e81948925962cb9
ToppCellhealthy_donor-Myeloid-Monocytic-SC_&_Eosinophil|healthy_donor / Disease condition, Lineage, Cell class and subclass

CCR3 SYTL4 CA8

3.55e-041823436bd6c32c48fecd6d03ac8a09e405b3b99bdc12ae
ToppCell343B-Lymphocytic-CD4_T-cell-Treg_cell_4|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

AFTPH RYR1 TRMT12

3.61e-041833433cbe0175d05fd39bc430de1ef471ff2c5b56460e
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Macrovascular_EC|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SORBS2 CH25H CA8

3.61e-04183343fc9a7ba148c22d0c8a46f6bc56c772929ac496f7
ToppCellMesenchymal_cells-Smooth_muscle|Mesenchymal_cells / Lineage and Cell class

SRPK3 SORBS1 SORBS2

3.67e-0418434383987abaedc26e6da477bc70d65e10b1ab1aea60
ToppCell3'-GW_trimst-1-LargeIntestine-Mesenchymal-mesothelial_cell-Mesothelium_(RGS5+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DAPK1 SORBS2 NCCRP1

3.73e-0418534311fbea1eb1d9a3e4480d0d2b0f7b02e2866b8142
ToppCellpdx-Tumor_cells-T0|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

DAPK1 SORBS1 SORBS2

3.73e-041853431d874608aa2062024323512f68889219471b2f00
ToppCellP28-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_vein|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SORBS2 CH25H CA8

3.79e-04186343153c8b2fd8a6e2141ca97c626f82e5f081f3180a
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ANGPTL1 NCCRP1 CA8

3.79e-04186343c2b65b8345487710704c3eb043e9bef2e2b1ff27
ToppCell(5)_Glands_duct|World / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)

MISP SORBS2 CA8

3.79e-04186343ad8d5010e5095508f4995e0c6c016a44e8ffb8dd
ToppCelldroplet-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l30|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SRPK3 SORBS1 SORBS2

3.85e-041873438e8b147258982b359447add5027318f5b6d51963
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)-Club_(non-nasal)_L.0.4.0.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CCDC85C SORBS2 SYTL4

3.85e-04187343f5a202d5f8eb57b57d80815ce98774e04c387383
ToppCellP03-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_vein|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SORBS2 CH25H CA8

3.91e-041883435eb107122064f0a99dfd445cc87d3766f7257216
ToppCellChildren_(3_yrs)-Endothelial-capillary_endothelial_cell_(Cap1)-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

SORBS1 SORBS2 HECW2

3.91e-04188343117dc80fa940e6aa1b0187a43fdde33f3fcb578f
ToppCellP28-Endothelial-large_vessel_endothelial_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SORBS2 CH25H CA8

3.91e-04188343263169029293e005bcffd87db20221fdd2d3917e
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ANGPTL1 NCCRP1 CA8

3.97e-041893431fd763c4e9904e866586a506ee7b0b285170481d
ToppCell5'-Adult-Appendix-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SORBS1 SORBS2 ANGPTL1

3.97e-04189343b6bb4327b4560d07d2b728abcc5f144f428948a5
ToppCell5'-Adult-Appendix-Mesenchymal-Pericytes|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SORBS1 SORBS2 ANGPTL1

3.97e-041893430daa8efac08dca9525d2b8d421952068cab4eb50
ToppCellCOVID-19-Endothelial_cells-Endothelial_cells_(general)|COVID-19 / group, cell type (main and fine annotations)

SORBS1 SORBS2 HECW2

4.03e-04190343812e11314c76c0179fbe5a9bea29b41ce5cbc93d
ToppCellControl-Endothelial-VE_Capillary_B|Endothelial / Disease state, Lineage and Cell class

SORBS1 SORBS2 HECW2

4.03e-041903437f3f419fffe02934b6f27b697f7a6401072491ed
ToppCellP15-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_vein|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SORBS2 CH25H CA8

4.03e-04190343d072bb285bd34d518b958e7c9ad44739c60b359c
ToppCellInfluenza_Severe-Non-classical_Monocyte|Influenza_Severe / Disease group and Cell class

CDH23 DAPK1 CA8

4.09e-04191343197edf6feb1cfc71d88e532d74f77305a42a3486
ToppCell(011)_pDC|World / immune cells in Peripheral Blood (logTPM normalization)

CCR3 RSPH1 PCSK4

4.09e-04191343d82ac4f6d9863734e09bf3cb71c1354a49b66b4f
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ANGPTL1 NCCRP1 CA8

4.09e-04191343feec8617678b778475747ad406c80231e07fd6f7
ToppCellChildren_(3_yrs)-Epithelial-club_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

DAPK1 SORBS2 CA8

4.09e-0419134323776c7302cead3881b39127398f3b3e0d27885e
ToppCelldroplet-Lung-1m-Endothelial-venous_endothelial|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SORBS2 CH25H CA8

4.15e-041923431990dc8a81594018a5bf596be99d0b5f0af0f58f
ToppCelldroplet-Lung-1m-Endothelial-venous_endothelial-vein_endothelial_cell-vein_endothelial_cell|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SORBS2 CH25H CA8

4.15e-04192343845cc9c18b4436b07dd3ce7980052683937546d2
ToppCelldroplet-Lung-30m-Endothelial-venous_endothelial-vein_endothelial_cell-vein_endothelial_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HECW2 CH25H CA8

4.15e-04192343452d54f0aca8657722d7ac61e8422921d08c06b3
ToppCelldroplet-Lung-30m-Endothelial-venous_endothelial-vein_endothelial_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HECW2 CH25H CA8

4.15e-041923437ddaca206599603d4d0b2afb73ed2850225d277d
ToppCell3'-GW_trimst-1-LargeIntestine-Mesenchymal-mesothelial_cell|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DAPK1 SORBS2 NCCRP1

4.15e-041923432f539653a20006bef814e6b4acd1023d6fdad5c6
ToppCelldroplet-Lung-30m-Endothelial-venous_endothelial|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HECW2 CH25H CA8

4.15e-04192343bf0b996aeedc34a79c71df3379ec9c1aabe06a8c
ToppCelldroplet-Lung-1m-Endothelial-venous_endothelial-vein_endothelial_cell|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SORBS2 CH25H CA8

4.15e-04192343c72a082c93a8825adbfef37f889ba3a7052f201b
ToppCellfacs-MAT-Fat-3m-Endothelial-endothelial_cell|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SORBS1 SORBS2 CLCA1

4.22e-04193343e164f6403a8b541ced08a6feec915d2e855036ea
ToppCellnucseq|World / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

DAPK1 CLVS1 MCF2L2

4.22e-04193343779276e775cb2492e8dd36436295a536084a6415
ToppCellP15-Endothelial-large_vessel_endothelial_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SORBS2 CH25H CA8

4.22e-041933435f9a7cd5f8eb9ac294cdb50518fedf872f3f78f5
ToppCellfacs-MAT-Fat-3m-Endothelial|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SORBS1 SORBS2 CLCA1

4.22e-04193343b32533afeff1905e188becaa09079e9699722e4b
ToppCellfacs-MAT-Fat-3m-Endothelial-nan|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SORBS1 SORBS2 CLCA1

4.22e-041933432ff573ba2c74583ed1cb071a3bbc01bb71117e5f
ToppCellfacs-Lung-ENDOMUCIN-18m-Endothelial-Vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SORBS2 CH25H CA8

4.28e-04194343e8102c8811333f04de7280b7d9b6b85cebb815ac
ToppCellfacs-Lung-ENDOMUCIN-18m-Endothelial-vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SORBS2 CH25H CA8

4.28e-041943434b0d63babb8a46ff45731d5f82b29ccaf6c9402d
ToppCelldroplet-Lung-18m-Endothelial-venous_endothelial-vein_endothelial_cell-vein_endothelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CLCA1 CH25H CA8

4.35e-041953430c15be3e7c238e329505dcbbe197a977d1019d45
ToppCelldroplet-Lung-18m-Endothelial-venous_endothelial|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CLCA1 CH25H CA8

4.35e-0419534345ac0fdbeb0982d798c613a6d15715d725608aa9
ToppCelldroplet-Lung-18m-Endothelial-venous_endothelial-vein_endothelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CLCA1 CH25H CA8

4.35e-041953435b1f04a745467876b09113ee17ababd3fcf9fb01
ToppCellfacs-GAT-Fat-3m-Endothelial|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SORBS1 SORBS2 CLCA1

4.41e-04196343b6cc1f466d45479764080d34b1daeb8243a5a9f3
ToppCell356C-Fibroblasts-Fibroblast-K_(Pericytes)|356C / Donor, Lineage, Cell class and subclass (all cells)

SORBS1 SORBS2 ANGPTL1

4.41e-04196343a5cc4f76e1a3825aaccba9a686d7da6f7e4300ff
ToppCell356C-Fibroblasts-Fibroblast-K_(Pericytes)-|356C / Donor, Lineage, Cell class and subclass (all cells)

SORBS1 SORBS2 ANGPTL1

4.41e-04196343476812fc1422aca8010d771eff11fa6081f15a2d
ToppCell3'-Broncho-tracheal-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell-Fibromyocytes|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SRPK3 SORBS1 ANGPTL1

4.41e-041963435159d8625d80c20eb28157b2603c8bde9d377a35
ToppCellMid-temporal_gyrus_(MTG)-Neuronal|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SORBS2 HECW1 KSR2

4.41e-04196343676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCellInfluenza_Severe-Non-classical_Monocyte|World / Disease group and Cell class

CDH23 DAPK1 CA8

4.41e-041963438ef9810ee99082a9c803c7ecad6ceb5710d16b54
ToppCelltumor_Lymph_Node_/_Brain|World / Location, Cell class and cell subclass

MISP SORBS2 CH25H

4.41e-04196343b39f938cbef54f08c53035738b97c76e7295733a
ToppCellfacs-GAT-Fat-3m-Endothelial-endothelial_cell|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SORBS1 SORBS2 CLCA1

4.41e-04196343ede6104cdfa4ee5287efcca9bbc36677cbf7a8d8
ToppCellfacs-GAT-Fat-3m-Endothelial-nan|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SORBS1 SORBS2 CLCA1

4.41e-04196343039044ab28c53391c34d8226fb8cf78549e63ef4
Diseaseangiopoietin-related protein 1 measurement

ANGPTL6 ANGPTL1

1.72e-0418322EFO_0801382
Diseasecolorectal adenocarcinoma (is_implicated_in)

RSPH1 PCSK4

6.63e-0435322DOID:0050861 (is_implicated_in)
Diseasecystic fibrosis (is_marker_for)

CCR3 CLCA1

2.07e-0362322DOID:1485 (is_marker_for)
Diseasemyocardial infarction (implicated_via_orthology)

CCR3 RYR1

2.34e-0366322DOID:5844 (implicated_via_orthology)
Diseasebasophil percentage of granulocytes

CCR3 RYR1

3.67e-0383322EFO_0007995
Diseasechronic obstructive pulmonary disease (is_marker_for)

CCR3 CLCA1

4.97e-0397322DOID:3083 (is_marker_for)

Protein segments in the cluster

PeptideGeneStartEntry
GGSNAVYWAARHGHV

DAPK1

411

P53355
QDIHDAHGLRYQWGG

AFTPH

706

Q6ULP2
RGGHYRSKHQDGIFW

ANGPTL1

456

O95841
EGEFGRVWYRILHGN

CDH23

1131

Q9H251
EYRGGYHDNHIVIRW

HECW2

1466

Q9P2P5
GWQVYRLGARDAHQG

MISP

91

Q8IVT2
YRGGYHDGHLVIRWF

HECW1

1501

Q76N89
RFGQVYHGRWHGEVA

KSR2

676

Q6VAB6
QRFGRHAAGAVWHEV

CCDC85C

106

A6NKD9
RWVQVSHVFRHYGPG

NCCRP1

226

Q6ZVX7
GGTLEYRHGQWVNHR

MCF2L2

186

Q86YR7
WRTNGVGRQVSHHYG

PCSK4

416

Q6UW60
VGNRGHHQYNRTGWR

TENT4A

741

Q5XG87
FGTVFRGRWHGDVAV

ARAF

321

P10398
IHYVRGHNWVFGHGM

CCR3

91

P51677
QGHEFELYEVRFHWG

CA8

106

P35219
VWHHGGHYRSRYQDG

ANGPTL6

431

Q8NI99
HGGTGRDGWIVDYIH

C17orf98

71

A8MV24
YVFNGHRGQRWHLGS

RYR1

1121

P21817
RLVPFGWYGGVVHHD

CH25H

226

O95992
LHWEVVTHGYFGLGV

PSMF1

26

Q92530
YGKTLRQHHGWVVRG

PLEKHA8P1

321

O95397
VWHHGRFGRNTFLGE

SYTL4

446

Q96C24
FRSGRHYWEVEVGGR

TRIM41

481

Q8WV44
GFHVDRRFGWDCHGL

IARS1

76

P41252
EGEWANDLRHGHGVY

RSPH1

91

Q8WYR4
FNGRYHVIRKLGWGH

SRPK1

76

Q96SB4
HVFWHFPGIFGTQER

RANBP6

161

O60518
IDQNWYEGEHHGRVG

SORBS2

896

O94875
NGRYHVVRKLGWGHF

SRPK3

76

Q9UPE1
EYGPQGRAFVHEWAH

CLCA1

146

A8K7I4
RFGGVHFVNQPWYIH

CLVS1

216

Q8IUQ0
GAVRVWDIVRHYGTH

TBL3

131

Q12788
IDQNWYEGEHHGRVG

SORBS1

826

Q9BX66
HGWVEHVDNGIRYKF

TRMT12

196

Q53H54