Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionbeta-adrenergic receptor kinase activity

GRK2 GRK3

5.67e-054622GO:0047696
GeneOntologyMolecularFunctionAMPA glutamate receptor activity

GRIA3 GRIA4

5.67e-054622GO:0004971
GeneOntologyMolecularFunctionG protein-coupled receptor kinase activity

GRK2 GRK3

1.97e-047622GO:0004703
GeneOntologyMolecularFunctionprotein serine/threonine kinase activity

GRK2 GRK3 PIK3CB STK17A CAMK2G NRK RPS6KA6

4.51e-04446627GO:0004674
GeneOntologyMolecularFunctionkinase activity

ADK GRK2 GRK3 PIK3CB STK17A CAMK2G NRK RPS6KA6 NME1

5.52e-04764629GO:0016301
MousePhenoincreased urine bicarbonate level

NOS1 SLC4A5

2.64e-053422MP:0011462
MousePhenoabnormal urine bicarbonate level

NOS1 SLC4A5

2.64e-053422MP:0011461
DomainGPCR_kinase

GRK2 GRK3

2.48e-047652IPR000239
DomainAGC-kinase_C

GRK2 GRK3 RPS6KA6

9.78e-0456653IPR000961
DomainAGC_KINASE_CTER

GRK2 GRK3 RPS6KA6

9.78e-0456653PS51285
DomainS_TK_X

GRK2 GRK3 RPS6KA6

9.78e-0456653SM00133
DomainVitD_rcpt

NR2C1 NR2C2

1.06e-0314652IPR000324
DomainARM-type_fold

XPO5 PIK3CB ANKAR UBR4 CKAP5 STAG3L3

1.15e-03339656IPR016024
DomainSer/Thr_kinase_AS

GRK2 GRK3 STK17A CAMK2G NRK RPS6KA6

1.50e-03357656IPR008271
DomainS_TKc

GRK2 GRK3 STK17A CAMK2G NRK RPS6KA6

1.54e-03359656SM00220
DomainPROTEIN_KINASE_ST

GRK2 GRK3 STK17A CAMK2G NRK RPS6KA6

1.60e-03362656PS00108
DomainIontro_rcpt

GRIA3 GRIA4

1.76e-0318652IPR001320
DomainLig_chan-Glu_bd

GRIA3 GRIA4

1.76e-0318652PF10613
DomainIono_rcpt_met

GRIA3 GRIA4

1.76e-0318652IPR001508
DomainGlu/Gly-bd

GRIA3 GRIA4

1.76e-0318652IPR019594
DomainLig_chan-Glu_bd

GRIA3 GRIA4

1.76e-0318652SM00918
DomainLig_chan

GRIA3 GRIA4

1.76e-0318652PF00060
DomainPBPe

GRIA3 GRIA4

1.76e-0318652SM00079
DomainProtein_kinase_ATP_BS

GRK2 GRK3 STK17A CAMK2G NRK RPS6KA6

2.02e-03379656IPR017441
DomainPkinase

GRK2 GRK3 STK17A CAMK2G NRK RPS6KA6

2.08e-03381656PF00069
DomainKinase-like_dom

GRK2 GRK3 PIK3CB STK17A CAMK2G NRK RPS6KA6

2.71e-03542657IPR011009
DomainTUDOR

PHF1 ARID4B

3.96e-0327652SM00333
DomainTudor

PHF1 ARID4B

4.87e-0330652IPR002999
DomainPROTEIN_KINASE_ATP

GRK2 GRK3 STK17A CAMK2G NRK RPS6KA6

5.18e-03459656PS00107
DomainRGS

GRK2 GRK3

6.59e-0335652PF00615
DomainRGS

GRK2 GRK3

6.59e-0335652SM00315
DomainRGS

GRK2 GRK3

6.96e-0336652PS50132
DomainProt_kinase_dom

GRK2 GRK3 STK17A CAMK2G NRK RPS6KA6

7.00e-03489656IPR000719
DomainPROTEIN_KINASE_DOM

GRK2 GRK3 STK17A CAMK2G NRK RPS6KA6

7.28e-03493656PS50011
PathwayREACTOME_ACTIVATION_OF_NMDA_RECEPTORS_AND_POSTSYNAPTIC_EVENTS

CAMK2G RPS6KA6 GRIA3 GRIA4

4.82e-0635464MM15109
PathwayREACTOME_UNBLOCKING_OF_NMDA_RECEPTORS_GLUTAMATE_BINDING_AND_ACTIVATION

CAMK2G GRIA3 GRIA4

4.15e-0521463M838
PathwayREACTOME_UNBLOCKING_OF_NMDA_RECEPTORS_GLUTAMATE_BINDING_AND_ACTIVATION

CAMK2G GRIA3 GRIA4

4.79e-0522463MM15104
PathwayREACTOME_TRAFFICKING_OF_AMPA_RECEPTORS

CAMK2G GRIA3 GRIA4

1.12e-0429463MM15028
PathwayREACTOME_TRAFFICKING_OF_AMPA_RECEPTORS

CAMK2G GRIA3 GRIA4

1.37e-0431463M7223
PathwayREACTOME_ACTIVATION_OF_NMDA_RECEPTORS_AND_POSTSYNAPTIC_EVENTS

CAMK2G RPS6KA6 GRIA3 GRIA4

2.44e-0494464M2843
PathwayWP_EFFECTS_OF_NITRIC_OXIDE

AOX1 NOS1

2.88e-048462M39677
Pubmed

STAG3, a novel gene encoding a protein involved in meiotic chromosome pairing and location of STAG3-related genes flanking the Williams-Beuren syndrome deletion.

STAG3L1 STAG3L2 STAG3L3

7.13e-08568310698974
Pubmed

Adjacent asparagines in the NR2-subunit of the NMDA receptor channel control the voltage-dependent block by extracellular Mg2+.

CAMK2G GRIA3 GRIA4

3.20e-06156839481670
Pubmed

A novel nuclear receptor heterodimerization pathway mediated by orphan receptors TR2 and TR4.

NR2C1 NR2C2

3.77e-0626829737983
Pubmed

Cloning of GRK2 cDNA from S49 murine lymphoma cells.

GRK2 GRK3

3.77e-0626828638670
Pubmed

Kinetic properties of human AMPA-type glutamate receptors expressed in HEK293 cells.

GRIA3 GRIA4

3.77e-06268212670305
Pubmed

Control of kinetic properties of AMPA receptor channels by nuclear RNA editing.

GRIA3 GRIA4

3.77e-0626827992055
Pubmed

Dissecting the roles of GRK2 and GRK3 in μ-opioid receptor internalization and β-arrestin2 recruitment using CRISPR/Cas9-edited HEK293 cells.

GRK2 GRK3

3.77e-06268233060647
Pubmed

Roles of testicular orphan nuclear receptors 2 and 4 in early embryonic development and embryonic stem cells.

NR2C1 NR2C2

3.77e-06268219131575
Pubmed

Forced TR2/TR4 expression in sickle cell disease mice confers enhanced fetal hemoglobin synthesis and alleviated disease phenotypes.

NR2C1 NR2C2

3.77e-06268222042865
Pubmed

G protein--coupled receptor kinases.

GRK2 GRK3

3.77e-0626828035170
Pubmed

Elimination of redundant synaptic inputs in the absence of synaptic strengthening.

GRIA3 GRIA4

3.77e-06268222090494
Pubmed

A bidirectional regulation between the TR2/TR4 orphan receptors (TR2/TR4) and the ciliary neurotrophic factor (CNTF) signaling pathway.

NR2C1 NR2C2

3.77e-0626829694834
Pubmed

Recent advances in the TR2 and TR4 orphan receptors of the nuclear receptor superfamily.

NR2C1 NR2C2

3.77e-06268212361719
Pubmed

Embryonic and fetal beta-globin gene repression by the orphan nuclear receptors, TR2 and TR4.

NR2C1 NR2C2

3.77e-06268217431400
Pubmed

Absence seizures in C3H/HeJ and knockout mice caused by mutation of the AMPA receptor subunit Gria4.

GRIA3 GRIA4

3.77e-06268218316356
Pubmed

Altered airway and cardiac responses in mice lacking G protein-coupled receptor kinase 3.

GRK2 GRK3

3.77e-06268210198406
Pubmed

G-protein coupled receptor kinase 2 and 3 expression in human detrusor cultured smooth muscle cells.

GRK2 GRK3

3.77e-06268211762794
Pubmed

GluA4 is indispensable for driving fast neurotransmission across a high-fidelity central synapse.

GRIA3 GRIA4

3.77e-06268221690196
Pubmed

Motor protein-dependent transport of AMPA receptors into spines during long-term potentiation.

CAMK2G GRIA3 GRIA4

5.71e-061868318311135
Pubmed

Human NK cells express CC chemokine receptors 4 and 8 and respond to thymus and activation-regulated chemokine, macrophage-derived chemokine, and I-309.

GRK2 GRK3

1.13e-05368210754297
Pubmed

Differential and bi-directional regulation between TR2/TR4 orphan nuclear receptors and a specific ligand mediated-peroxisome proliferator-activated receptor alpha in human HaCaT keratinocytes.

NR2C1 NR2C2

1.13e-05368212615366
Pubmed

The number and distribution of AMPA receptor channels containing fast kinetic GluA3 and GluA4 subunits at auditory nerve synapses depend on the target cells.

GRIA3 GRIA4

1.13e-05368228397107
Pubmed

Differential effects of CC chemokines on CC chemokine receptor 5 (CCR5) phosphorylation and identification of phosphorylation sites on the CCR5 carboxyl terminus.

GRK2 GRK3

1.13e-05368210085131
Pubmed

Cardiac function in mice overexpressing the beta-adrenergic receptor kinase or a beta ARK inhibitor.

GRK2 GRK3

1.13e-0536827761854
Pubmed

The N-termini of GRK2 and GRK3 simulate the stimulating effects of RKIP on β-adrenoceptors.

GRK2 GRK3

1.13e-05368231604529
Pubmed

Fas-associated death domain protein interacts with methyl-CpG binding domain protein 4: a potential link between genome surveillance and apoptosis.

XPO5 FADD

1.13e-05368212702765
Pubmed

The TR2 and TR4 orphan nuclear receptors repress Gata1 transcription.

NR2C1 NR2C2

1.13e-05368217974920
Pubmed

Study on GRIA2, GRIA3 and GRIA4 genes highlights a positive association between schizophrenia and GRIA3 in female patients.

GRIA3 GRIA4

1.13e-05368218163426
Pubmed

Blockage of Ca(2+)-permeable AMPA receptors suppresses migration and induces apoptosis in human glioblastoma cells.

GRIA3 GRIA4

1.13e-05368212172541
Pubmed

Orphanin FQ/nociceptin-mediated desensitization of opioid receptor-like 1 receptor and mu opioid receptors involves protein kinase C: a molecular mechanism for heterologous cross-talk.

GRK2 GRK3

1.13e-05368212130708
Pubmed

An embryonic/fetal beta-type globin gene repressor contains a nuclear receptor TR2/TR4 heterodimer.

NR2C1 NR2C2

1.13e-05368212093744
Pubmed

PH domain of G protein-coupled receptor kinase-2 binds to protein kinase C (PKC) and negatively regulates activity of PKC kinase.

GRK2 PLEK

1.13e-05368212456365
Pubmed

Synaptic AMPA receptor plasticity and behavior.

GRIA3 GRIA4

1.13e-05368219217372
Pubmed

Hypercapnic duty cycle is an intermediate physiological phenotype linked to mouse chromosome 5.

GRK3 NOS1

1.13e-05368212794091
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

NR2C1 NR2C2 CAMK2G UBR4 CKAP5 ZBTB9 NME1

1.78e-0541868734709266
Pubmed

A phylogenetic analysis reveals an unusual sequence conservation within introns involved in RNA editing.

GRIA3 GRIA4

2.25e-05468210688364
Pubmed

Signalling through AMPA receptors on oligodendrocyte precursors promotes myelination by enhancing oligodendrocyte survival.

GRIA3 GRIA4

2.25e-05468228608780
Pubmed

AMPA receptor subunits expressed by single astrocytes in the juvenile mouse hippocampus.

GRIA3 GRIA4

2.25e-0546829221927
Pubmed

Interaction proteomics reveals brain region-specific AMPA receptor complexes.

GRIA3 GRIA4

2.25e-05468225337787
Pubmed

Auditory sensitivity regulation via rapid changes in expression of surface AMPA receptors.

GRIA3 GRIA4

2.25e-05468217828255
Pubmed

Reduced expression of G protein-coupled receptor kinases in schizophrenia but not in schizoaffective disorder.

GRK2 GRK3

2.25e-05468221784156
Pubmed

The N-terminal domain modulates α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor desensitization.

GRIA3 GRIA4

2.25e-05468224652293
Pubmed

Electrophysiological properties of AMPA receptors are differentially modulated depending on the associated member of the TARP family.

GRIA3 GRIA4

2.25e-05468217409242
Pubmed

Compound loss of function of nuclear receptors Tr2 and Tr4 leads to induction of murine embryonic β-type globin genes.

NR2C1 NR2C2

2.25e-05468225561507
Pubmed

Aberrant formation of glutamate receptor complexes in hippocampal neurons of mice lacking the GluR2 AMPA receptor subunit.

GRIA3 GRIA4

2.25e-05468214561864
Pubmed

Clustering of AMPA receptors by the synaptic PDZ domain-containing protein PICK1.

GRIA3 GRIA4

2.25e-05468210027300
Pubmed

Chromosomal localization of human glutamate receptor genes.

GRIA3 GRIA4

2.25e-0546821319477
Pubmed

Characterization of phosphorylation sites on the glutamate receptor 4 subunit of the AMPA receptors.

CAMK2G GRIA4

2.25e-05468210366608
Pubmed

AMPA receptors regulate dynamic equilibrium of presynaptic terminals in mature hippocampal networks.

GRIA3 GRIA4

2.25e-05468212692557
Pubmed

Essential role of beta-adrenergic receptor kinase 1 in cardiac development and function.

GRK2 GRK3

2.25e-0546828917529
Pubmed

Flip and flop splice variants of AMPA receptor subunits in the spinal cord of amyotrophic lateral sclerosis.

GRIA3 GRIA4

2.25e-05468212125045
Pubmed

Phosphorylation of the type 1A angiotensin II receptor by G protein-coupled receptor kinases and protein kinase C.

GRK2 GRK3

2.25e-0546828662816
Pubmed

Hierarchical organization of multi-site phosphorylation at the CXCR4 C terminus.

GRK2 GRK3

2.25e-05468223734232
Pubmed

Altered glutamate protein co-expression network topology linked to spine loss in the auditory cortex of schizophrenia.

GRIA3 GRIA4

2.25e-05468225433904
Pubmed

AMPA receptor-mediated excitotoxicity in human NT2-N neurons results from loss of intracellular Ca2+ homeostasis following marked elevation of intracellular Na+.

GRIA3 GRIA4

2.25e-0546829648857
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

NR2C1 NR2C2 ZNF136 TCF7L2 ARID4B GNL2 ZBTB9 TMPO

2.45e-0560868836089195
Pubmed

NMDA Receptors Regulate the Development of Neuronal Intrinsic Excitability through Cell-Autonomous Mechanisms.

GRIA3 GRIA4

3.75e-05568229163060
Pubmed

RNA editing in brain controls a determinant of ion flow in glutamate-gated channels.

GRIA3 GRIA4

3.75e-0556821717158
Pubmed

Enhanced contractility and decreased beta-adrenergic receptor kinase-1 in mice lacking endogenous norepinephrine and epinephrine.

GRK2 GRK3

3.75e-05568210338466
Pubmed

Differential regulation of AMPA receptor subunit trafficking by palmitoylation of two distinct sites.

GRIA3 GRIA4

3.75e-05568216129400
Pubmed

Allosteric modulation of AMPA-type glutamate receptors increases activity of the promoter for the neural cell adhesion molecule, N-CAM.

GRIA3 GRIA4

3.75e-0556829482932
Pubmed

Calcium-permeable AMPA receptor plasticity is mediated by subunit-specific interactions with PICK1 and NSF.

GRIA3 GRIA4

3.75e-05568215797551
Pubmed

Regulation of RIPK1 activation by TAK1-mediated phosphorylation dictates apoptosis and necroptosis.

NR2C2 FADD

3.75e-05568228842570
Pubmed

beta2-Adrenergic receptor regulation by GIT1, a G protein-coupled receptor kinase-associated ADP ribosylation factor GTPase-activating protein.

GRK2 GRK3

5.62e-0566829826657
Pubmed

Cell adhesion molecule L1 affects the rate of differentiation of enteric neurons in the developing gut.

L1CAM NOS1

5.62e-05668219235728
Pubmed

Function of the cytoplasmic tail of human calcitonin receptor-like receptor in complex with receptor activity-modifying protein 2.

GRK2 GRK3

5.62e-05668220074556
Pubmed

Phosphoinositide 3-kinase regulates beta2-adrenergic receptor endocytosis by AP-2 recruitment to the receptor/beta-arrestin complex.

GRK2 PIK3CB

5.62e-05668212163475
Pubmed

Combinatorial depletions of G-protein coupled receptor kinases in immune cells identify pleiotropic and cell type-specific functions.

GRK2 GRK3

5.62e-05668236451830
Pubmed

HIV-1 subtypes B and C Tat differentially impact synaptic plasticity expression and implicates HIV-associated neurocognitive disorders.

CAMK2G GRIA3 NOS1

5.74e-053868325613138
Pubmed

Interaction network of human early embryonic transcription factors.

KMT2C NR2C1 NR2C2 TCF7L2 ARID4B ZBTB9

6.54e-0535168638297188
Pubmed

Glutamate receptor δ2 is essential for input pathway-dependent regulation of synaptic AMPAR contents in cerebellar Purkinje cells.

GRIA3 GRIA4

7.86e-05768221368048
Pubmed

Hippocampal AMPA receptor assemblies and mechanism of allosteric inhibition.

GRIA3 GRIA4

7.86e-05768233981040
Pubmed

Impairment of AMPA receptor function in cerebellar granule cells of ataxic mutant mouse stargazer.

GRIA3 GRIA4

7.86e-05768210407040
Pubmed

Glutamate receptors in cortical plasticity: molecular and cellular biology.

GRIA3 GRIA4

7.86e-0576829016303
Pubmed

Glutamate receptors: brain function and signal transduction.

GRIA3 GRIA4

7.86e-0576829651535
Pubmed

Members of the G protein-coupled receptor kinase family that phosphorylate the beta2-adrenergic receptor facilitate sequestration.

GRK2 GRK3

7.86e-0576828672451
Pubmed

TARP γ-2 and γ-8 Differentially Control AMPAR Density Across Schaffer Collateral/Commissural Synapses in the Hippocampal CA1 Area.

GRIA3 GRIA4

7.86e-05768227076426
Pubmed

Determination of bradykinin B2 receptor in vivo phosphorylation sites and their role in receptor function.

GRK2 GRK3

7.86e-05768211517230
Pubmed

Hippocampal AMPA receptor gating controlled by both TARP and cornichon proteins.

GRIA3 GRIA4

1.05e-04868221172611
Pubmed

The CREB/CREM transcription factors negatively regulate early synaptogenesis and spontaneous network activity.

L1CAM GRIA3

1.05e-04868219144833
Pubmed

Synaptic profiles during neurite extension, refinement and retraction in the developing cochlea.

GRIA3 GRIA4

1.05e-04868223217150
Pubmed

Phosphatidylinositol-3-kinase-atypical protein kinase C signaling is required for Wnt attraction and anterior-posterior axon guidance.

PIK3CB L1CAM

1.34e-04968218367611
Pubmed

Changes of several brain receptor complexes in the cerebral cortex of patients with Alzheimer disease: probable new potential pharmaceutical targets.

GRIA3 GRIA4

1.34e-04968224292102
Pubmed

Molecular determinants of response kinetics of mouse M1 intrinsically-photosensitive retinal ganglion cells.

GRK2 GRK3

1.34e-04968234873237
Pubmed

Expression of glutamate receptor subunit genes during development of the mouse retina.

GRIA3 GRIA4

1.34e-0496829051806
Pubmed

Cloning, expression, and chromosomal localization of beta-adrenergic receptor kinase 2. A new member of the receptor kinase family.

GRK2 GRK3

1.68e-04106821869533
Pubmed

Sleeping Beauty mutagenesis reveals cooperating mutations and pathways in pancreatic adenocarcinoma.

KMT2C ARID4B

1.68e-041068222421440
Pubmed

Polymorphisms in innate immunity genes and patients response to dendritic cell-based HIV immuno-treatment.

PIK3CB PLA2G2A CCL1 NOS1

1.72e-0414168420056178
Pubmed

A generic approach for the purification of signaling complexes that specifically interact with the carboxyl-terminal domain of G protein-coupled receptors.

GRK2 NOS1 SLC4A5

1.74e-045568318448421
Pubmed

Interaction of nuclear receptor zinc finger DNA binding domains with histone deacetylase.

NR2C1 NR2C2

2.05e-041168212943985
Pubmed

Abnormal nonshivering thermogenesis in mice with inherited defects of fatty acid oxidation.

GRK3 NOS1

2.05e-04116829802886
Pubmed

The PDZ proteins PICK1, GRIP, and syntenin bind multiple glutamate receptor subtypes. Analysis of PDZ binding motifs.

GRIA3 GRIA4

2.45e-041268211891216
Pubmed

EB1-binding-myomegalin protein complex promotes centrosomal microtubules functions.

CAMK2G CKAP5 TMPO

2.61e-046368329162697
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

KMT2C NR2C1 NR2C2 TCF7L2 XPO5 CAMK2G CKAP5 ZBTB9 TMPO

2.89e-04110368934189442
Pubmed

Glutamatergic gene variants impact the clinical profile of efficacy and side effects of haloperidol.

GRIA3 GRIA4

2.90e-041368220859245
Pubmed

Deletion of olfactomedin 2 induces changes in the AMPA receptor complex and impairs visual, olfactory, and motor functions in mice.

GRIA3 GRIA4

2.90e-041368225218043
Pubmed

Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment.

GRK3 L1CAM GRIA3 GRIA4 NOS1

3.09e-0430068519086053
Pubmed

A directed protein interaction network for investigating intracellular signal transduction.

KMT2C NR2C1 GRK2 PIK3CB UBR4 RPS6KA6 FADD PLA2G2A RPP14

3.32e-04112468921900206
Pubmed

From the Cover: Indispensability of the glutamate transporters GLAST and GLT1 to brain development.

L1CAM GRIA4

3.38e-041468216880397
Pubmed

Genetics meets metabolomics: a genome-wide association study of metabolite profiles in human serum.

FGF12 PLEK

3.89e-041568219043545
Cytoband10q22

ADK CAMK2G

3.26e-041868210q22
Cytoband7q11.23

STAG3L1 STAG3L2 STAG3L3

4.15e-04976837q11.23
Cytoband11q13.3

LTO1 FADD

4.90e-042268211q13.3
Cytoband12q22

NR2C1 TMPO

1.71e-034168212q22
GeneFamilyGlutamate ionotropic receptor AMPA type subunits

GRIA3 GRIA4

3.46e-0544421200
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

GRK2 GRK3 PLEK FARP2

1.56e-03206444682
ToppCellcellseq-Mesenchymal-Fibroblastic-Fibroblastic_1-Mesothelial|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

NRK AOX1 PLA2G2A GRIA4 ABCA8 SVEP1

3.73e-071866767812ed80d2378aca9957ef22fc3c8fb7fb58434b
ToppCell3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CCDC154 AOX1 PLA2G2A ABCA8 SVEP1

6.14e-06172675e37c0b5b547a7345179ab258dd2141fec7064c17
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B-B_cell|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

ADK GRK3 ARID4B PLEK FARP2

6.32e-06173675d56e337eae727a29cd53cfd628e1b3c0a98e1f51
ToppCelldroplet-Marrow-nan-3m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRK3 PIK3CB DDX60 L1CAM PLEK

6.68e-06175675cf53a15bfb37b6019e7052ffdf594a9ac040900e
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.4.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

AOX1 PLA2G2A GRIA3 ABCA8 SVEP1

8.98e-0618667507d94d5d1c2fe7bb909a07ca81058a0eabc65c60
ToppCellnucseq-Immune-Immune_Myeloid-pMON-pMON|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

TCF7L2 GRK2 GRK3 CHST15 TMPO

1.10e-05194675e237384b02be460d44eeada3026a5691c66f6fc1
ToppCellnucseq-Immune-Immune_Myeloid-pMON|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

TCF7L2 GRK2 GRK3 CHST15 TMPO

1.10e-051946750bc83ae79873a5e473e6e1e3111924cd003986a1
ToppCellCOVID-19_Mild|World / Disease group, lineage and cell class

KMT2C SAMD9 GRK2 ARID4B DDX60

1.19e-051976755c33454b10023decd2f5ccda9229b6512659711e
ToppCellPBMC-Mild|PBMC / Location, Disease Group, Cell group, Cell class (2021.03.09)

KMT2C SAMD9 GRK2 ARID4B DDX60

1.21e-0519867544417089b62056269cac38d3134ff209c05b7007
ToppCellPBMC-Mild|PBMC / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

KMT2C SAMD9 GRK2 ARID4B DDX60

1.21e-0519867528ef3fc4c17dcb765537b75917f7db78baa522db
ToppCellBiopsy_Control_(H.)-Mesenchymal-Mesothelial_cells|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

NRK AOX1 PLA2G2A ABCA8 SVEP1

1.24e-05199675ca970114b5aef4518ce580897a62ac88688b2671
ToppCellBiopsy_Other_PF-Mesenchymal-PLIN2+_Fibroblasts|Biopsy_Other_PF / Sample group, Lineage and Cell type

AOX1 PLA2G2A GRIA3 ABCA8 SVEP1

1.27e-052006750aa316b71f195ecf17ee897e307f8928a755a637
ToppCellVE|World / Condition, Cell_class and T cell subcluster

SAMD9 GRK2 STK17A DDX60 TMPO

1.27e-052006758ae7cb81de3ffac5acdf3466d4b516d80cac95d3
ToppCellBiopsy_Control_(H.)-Mesenchymal-PLIN2+_Fibroblasts|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

AOX1 PLA2G2A GRIA4 ABCA8 SVEP1

1.27e-05200675cdaf462b1db29dab61038eeab5ddd3eef3386763
ToppCelldroplet-Lung-nan-3m-Myeloid-Nonclassical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCF7L2 GRK3 L1CAM PLEK

8.34e-051536746dcab3d50ab50051955204dc4e4a64c1ca855bcd
ToppCelldroplet-Lung-nan-3m-Myeloid-non-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCF7L2 GRK3 L1CAM PLEK

8.34e-05153674f6ef14d949107c08cb3690e26ec91e194cb43518
ToppCell367C-Fibroblasts-Fibroblast-D-|367C / Donor, Lineage, Cell class and subclass (all cells)

AOX1 PLA2G2A ABCA8 SVEP1

8.56e-05154674dd3d34f065820e706515a13619f19a5b12734c8e
ToppCell367C-Fibroblasts-Fibroblast-D|367C / Donor, Lineage, Cell class and subclass (all cells)

AOX1 PLA2G2A ABCA8 SVEP1

8.56e-051546744bfda1c41efbb86d829b3797d1168bf2587c3c97
ToppCellLPS-antiTNF-Myeloid-Monocytes,_Macrophages-Neutrophils|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GRK3 TECPR2 PIK3CB PLEK

9.92e-051606745d8d97c3da5837ba5fe743d2f8438f5cb7cea64b
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

GRK3 PLA2G2A ABCA8 SVEP1

1.02e-04161674a006491c991e6a134be20ad75092a91f3b7c3c91
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

ADK GRK3 PLEK FARP2

1.07e-041636746bed27d2f67a430a847da5eb47878d14b4949c45
ToppCellfacs-Lung-EPCAM-24m-Myeloid-Nonclassical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRK2 GRK3 L1CAM PLEK

1.09e-0416467415d52666e5150e7c34b1f641a937fb2d5e8aaf8a
ToppCellfacs-Lung-EPCAM-24m-Myeloid-non-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRK2 GRK3 L1CAM PLEK

1.09e-04164674d622f0d8d8bad48dfdf160ec63c545df192637a9
ToppCelldroplet-Lung-30m-Hematologic-myeloid-non-classical_monocyte-nonclassical_monocyte_l4|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TCF7L2 GRK3 L1CAM PLEK

1.20e-04168674d823979335ac6b5d1f062ebb741c759d2f919dbf
ToppCelldroplet-Kidney-nan-3m-Epithelial-kidney_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRK2 GRK3 DUSP6 PLEK

1.20e-04168674f45dbcd7753117a3e41e1412bce2100d52fa7fd0
ToppCelldroplet-Lung-18m-Hematologic-myeloid-non-classical_monocyte-nonclassical_monocyte_l4|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TCF7L2 GRK3 L1CAM PLEK

1.20e-041686744b5be7c6662eceddf90a65015f12908278d1664e
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

AOX1 PLA2G2A ABCA8 SVEP1

1.20e-041686744b2d29a7843bf45922038c093ca7ec0600756adc
ToppCellfacs-Lung-24m-Hematologic-myeloid-non-classical_monocyte-nonclassical_monocyte_l4|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

GRK2 GRK3 L1CAM PLEK

1.20e-04168674c0aef5947b1d7e2c81a7481c509feda1687fcd7f
ToppCelldroplet-Lung-18m-Hematologic-myeloid-non-classical_monocyte|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TCF7L2 GRK3 L1CAM PLEK

1.20e-04168674689c41f6e9f65381570991cc311cba49a57ec955
ToppCellfacs-Lung-24m-Hematologic-myeloid-non-classical_monocyte|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

GRK2 GRK3 L1CAM PLEK

1.20e-04168674c861f80aa12caf54a94d93e38539ff41dc5227a6
ToppCelldroplet-Lung-30m-Hematologic-myeloid-non-classical_monocyte|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TCF7L2 GRK3 L1CAM PLEK

1.20e-04168674f377ff4c066a9857ad14d245e56325ad220e22e1
ToppCelldroplet-Lung-nan-18m-Myeloid-non-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCF7L2 GRK3 L1CAM PLEK

1.22e-04169674ba023ee7bb165c2bfbefc2d969ff32ca1eeed33b
ToppCelldroplet-Lung-LUNG-30m-Myeloid-Nonclassical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCF7L2 GRK3 L1CAM PLEK

1.22e-04169674411556e93adcbb7e4d79b02f3dc72963ec8a0759
ToppCelldroplet-Lung-nan-18m-Myeloid-Nonclassical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCF7L2 GRK3 L1CAM PLEK

1.22e-04169674c96e0f3241d13926dbee9f91c0c8c5bfa7479a0d
ToppCelldroplet-Lung-LUNG-30m-Myeloid-non-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCF7L2 GRK3 L1CAM PLEK

1.22e-0416967439b1acfd099abb9de18c29c05c7a67709ea76775
ToppCelltumor_Lymph_Node_/_Brain-Fibroblasts-COL13A1+_matrix_FBs|Fibroblasts / Location, Cell class and cell subclass

PLA2G2A TMPO ABCA8 SVEP1

1.22e-0416967484b898a9fd8ced67c6a501d5cef6416f519902c4
ToppCellE17.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CHST15 ECSCR C16orf96 SVEP1

1.25e-041706747fa022471e14ac8a3bc147c793368a4d56a8e591
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

AOX1 PLA2G2A ABCA8 SVEP1

1.28e-041716745d31fc9b60329d4ae3c77e4ca679359d9314397d
ToppCell3'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature-Differentiating_glia|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DUSP6 L1CAM CFAP61 ABCA8

1.31e-04172674bc3ed05fdd94d5e1f19285aea867b1453292baec
ToppCelldroplet-Lung-LUNG-1m-Myeloid-non-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCF7L2 GRK3 L1CAM PLEK

1.40e-04175674c8cfe0ac0c1ac447c626a623cc49692a0b177a1c
ToppCelldroplet-Lung-LUNG-1m-Myeloid-Nonclassical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCF7L2 GRK3 L1CAM PLEK

1.40e-0417567461fbd8f685d3daad46449e4c0386a38886496566
ToppCell343B-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)-|343B / Donor, Lineage, Cell class and subclass (all cells)

AOX1 PLA2G2A ABCA8 SVEP1

1.43e-041766742e94bbe17c0bb65dc58b4ebc0cb829258bd7373b
ToppCelltumor_Lymph_Node_/_Brain-Fibroblasts-COL13A1+_matrix_FBs|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

AOX1 PLA2G2A ABCA8 SVEP1

1.43e-04176674510f9a14dc1c151d24d079e0cc004cdf4f86336c
ToppCell343B-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)|343B / Donor, Lineage, Cell class and subclass (all cells)

AOX1 PLA2G2A ABCA8 SVEP1

1.43e-04176674f33ab41d121b59d871ad7d48ca021524a027d2ef
ToppCell356C-Fibroblasts-Fibroblast-E-|356C / Donor, Lineage, Cell class and subclass (all cells)

AOX1 PLA2G2A ABCA8 SVEP1

1.49e-04178674a493a277d175e5e153410a745b26ebe2e0839ea0
ToppCell356C-Fibroblasts-Fibroblast-E|356C / Donor, Lineage, Cell class and subclass (all cells)

AOX1 PLA2G2A ABCA8 SVEP1

1.49e-04178674371218babddfd3d8a7bb82a46ce65327ee3fcf12
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Monocytic-Non-classical_Monocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GRK3 CHST15 DUSP6 PLEK

1.59e-041816748657d35cd3dff6c89d0fde67d7e7e81e1d6c8884
ToppCelltumor_Lung-Fibroblasts-Undetermined|tumor_Lung / Location, Cell class and cell subclass

AOX1 PLA2G2A ABCA8 SVEP1

1.59e-0418167453bcab4d6df4a3255d81877ba22fb95d4492ce9f
ToppCellFLU-Healthy-0|FLU / Virus stimulation, Condition and Cluster

STK17A L1CAM CCDC154 PLEK

1.66e-04183674058604ddb06b3bef131183d86b83b422dae8f6cb
ToppCellCalu_3-infected|Calu_3 / Cell line, Condition and Strain

KMT2C SAMD9 ARID4B DDX60

1.66e-041836748f7f5000645f24f20a8d7700c4df1f8953a1780b
ToppCellFLU-Healthy-0|Healthy / Virus stimulation, Condition and Cluster

STK17A L1CAM CCDC154 PLEK

1.66e-041836747a6f18246c39864479e114f698581f667fa9c600
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-4|TCGA-Pancreas / Sample_Type by Project: Shred V9

NRK PABPC4L ABCA8 SVEP1

1.70e-0418467467164bb6bcae7322cb89b585c7aa10bce35b0ecd
ToppCellAdult-Mesenchymal-matrix_fibroblast_2_cell-D122|Adult / Lineage, Cell type, age group and donor

AOX1 GRIA3 ABCA8 SVEP1

1.70e-041846742b7e6f91e11c228f0521e099886867d9e998e78d
ToppCellCOVID-19-Fibroblasts-Adventitial_FB|COVID-19 / group, cell type (main and fine annotations)

AOX1 PLA2G2A ABCA8 SVEP1

1.73e-04185674a5aebf2b9b05b550d021272731d68af9a6b1229d
ToppCell343B-Fibroblasts-Fibroblast-E-|343B / Donor, Lineage, Cell class and subclass (all cells)

ZNF613 AOX1 PLA2G2A ABCA8

1.77e-041866741bac7825c2fe3e6cdff65026b09b9ccaa40fa27f
ToppCell343B-Fibroblasts-Fibroblast-E|343B / Donor, Lineage, Cell class and subclass (all cells)

ZNF613 AOX1 PLA2G2A ABCA8

1.77e-0418667459db239f1864a5d4f1570c93219dbd7ac5b6db35
ToppCellTCGA-Head_and_Esophagus-Primary_Tumor-Head_and_Neck_Carcinoma-Squamous_Cell_Carcinoma-9|TCGA-Head_and_Esophagus / Sample_Type by Project: Shred V9

ADK STK17A DUSP6 FAM83A

1.81e-04187674f002ff1a7cb7577f28acff008bc2aa561ac1a4bf
ToppCellControl-Fibroblasts-Adventitial_FB|Control / group, cell type (main and fine annotations)

AOX1 PLA2G2A ABCA8 SVEP1

1.84e-04188674706a26c372add839d947749f0521a0e1f5c9b0ec
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

AOX1 PLA2G2A ABCA8 SVEP1

1.84e-04188674e18065bbc26d6f3774fd1f478fb41d8fb555fa26
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

AOX1 PLA2G2A ABCA8 SVEP1

1.88e-04189674d531399749409d614adca13d181830c6e3287508
ToppCellAdult-Mesenchymal-matrix_fibroblast_2_cell-D175|Adult / Lineage, Cell type, age group and donor

AOX1 PLA2G2A ABCA8 SVEP1

1.92e-041906747dcca3469f3a3b70db0420cb94f7765f39492f06
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Myeloid-Monocytic-Classical_Monocyte-Mono_c2-CD14-HLA-DPB1|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

TCF7L2 CHST15 DUSP6 PLEK

1.92e-041906744b9bac17eb7ceadada932f2d4a20a5f176088d53
ToppCell10x5'-Lung-Myeloid_Monocytic-Nonclassical_monocytes|Lung / Manually curated celltypes from each tissue

TCF7L2 GRK2 CHST15 TMPO

1.96e-04191674a862a571625ab7238589ff201e5954f602c3bd7e
ToppCellLV-02._Fibroblast_II|World / Chamber and Cluster_Paper

NRK PLA2G2A ABCA8 SVEP1

1.96e-04191674d36565257ccba8c1bbed2c1c01be66a9cbb5f834
ToppCellRV-01._Fibroblast_I|World / Chamber and Cluster_Paper

AOX1 PLA2G2A ABCA8 SVEP1

1.96e-0419167470c067c54084bfb02c29bab085f4defd477194fb
ToppCellRV-01._Fibroblast_I|RV / Chamber and Cluster_Paper

AOX1 PLA2G2A ABCA8 SVEP1

2.00e-04192674356160b113c3305a61ceeaff33ce3c9da0be2878
ToppCellAdult-Mesenchymal-matrix_fibroblast_2_cell|Adult / Lineage, Cell type, age group and donor

AOX1 PLA2G2A ABCA8 SVEP1

2.00e-04192674d21f0f577156f17c899b08871046a26b88aea011
ToppCellMesenchymal-matrix_fibroblast_2_cell|World / Lineage, Cell type, age group and donor

NRK AOX1 ABCA8 SVEP1

2.00e-04192674a769158c49d2b208c4224d85e7ae68c85cc372ed
ToppCellMonocytes-Inflammatory_CD16+_macrophages|World / Immune cells in Kidney/Urine in Lupus Nephritis

TCF7L2 GRK3 CHST15 DUSP6

2.00e-041926744be5c2c946337cd3e710137726358adca563f146
ToppCellCOVID-19_Moderate-CD4+_T_activated|World / disease group, cell group and cell class

PHF1 SUSD4 SAMD9 DDX60

2.04e-04193674c2a2a2c14a7085690262db5c2a70e38db67dee18
ToppCellSmart-seq2-spleen_(Smart-seq2)-myeloid|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

GRK2 CHST15 DUSP6 PLEK

2.04e-041936745f732598cdb6f3bd519f044a9cc553bd2e8b1052
ToppCell3'-Distal_airway-Immune_Myeloid-Myeloid_monocytic-non-classical_monocyte-Non-classical_monocytes-Non-classical_monocytes_L.1.2.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GRK2 GRK3 CHST15 DUSP6

2.04e-04193674cb0fb21510124883e716780bea46575620c366b8
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

SAMD9 STK17A DDX60 PLEK

2.04e-04193674fce4f805e53669acb4c188f87ac7d84408c0c218
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

SAMD9 STK17A DDX60 PLEK

2.04e-041936746e1498153a7766c03fddbda1701dbf1596d21736
ToppCellLV-01._Fibroblast_I|LV / Chamber and Cluster_Paper

AOX1 PLA2G2A ABCA8 SVEP1

2.04e-04193674dc17f3b9758936d428cf17f77a1ce6d4c479b165
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

AOX1 PLA2G2A ABCA8 SVEP1

2.04e-04193674261cafc167c86ab277be4ea7f08b0173e2dde26e
ToppCell3'-Distal_airway-Immune_Myeloid-Myeloid_monocytic-non-classical_monocyte|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GRK2 GRK3 CHST15 DUSP6

2.04e-041936740c207879f994c227dcd1322faa69ec9e3749cdaa
ToppCell3'-Distal_airway-Immune_Myeloid-Myeloid_monocytic-non-classical_monocyte-Non-classical_monocytes|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GRK2 GRK3 CHST15 DUSP6

2.04e-041936740fbbfcc803edc3cd96b35467ad5cc573af07fd67
ToppCellfacs-Brain_Myeloid-Cortex-3m-Myeloid-nan|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAJB13 ECSCR DUSP6 PLEK

2.08e-0419467450c5fc349533281a426bc7227a8ea9eca8d11985
ToppCellCOVID_non-vent-Myeloid-Monocytic-CD16+_Monocyte|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

TCF7L2 GRK3 CHST15 DUSP6

2.08e-041946741b4a17d58793e8889484fe592dce8ee1e8fe77a9
ToppCellhealthy_donor-Myeloid-Monocytic-CD16+_Monocyte|healthy_donor / Disease condition, Lineage, Cell class and subclass

TCF7L2 GRK3 CHST15 DUSP6

2.08e-04194674ecf746ef1c5c4d6d9ca06a6d3e3778670b5700c2
ToppCellIPF-Stromal-Fibroblast|Stromal / Disease state, Lineage and Cell class

AOX1 PLA2G2A ABCA8 SVEP1

2.08e-04194674da3e1d39575969a069ef43e552afe94b2f441d0b
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_monocytic-non-classical_monocyte-Non-classical_monocytes-Non-classical_monocytes_L.1.2.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GRK2 GRK3 CHST15 PLEK

2.08e-0419467416c6fcbd36d473b883fb5361caca86eb134767ab
ToppCellPBMC-Mild|PBMC / Compartment, Disease Groups and Clusters

KMT2C SAMD9 DDX60 PLEK

2.08e-04194674d1366b169d14011194e61d16b6b0953349febc78
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibro-meso-mesothelial_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

AOX1 PLA2G2A ABCA8 SVEP1

2.08e-0419467479baee8b35b7707bbeb07c73b5e17b68bcd7bbc2
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibro-meso|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

AOX1 PLA2G2A ABCA8 SVEP1

2.08e-04194674f6e348f1f35c526cad6c349f1fdd0bd92d18aa3c
ToppCellfacs-Brain_Myeloid-Cortex-3m|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAJB13 ECSCR DUSP6 PLEK

2.08e-041946741662b110f84584e75150df0ac970e7df82f26e7e
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibro-meso-mesothelial_cell-Mesothelium-Mesothelium_L.2.6.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

AOX1 PLA2G2A ABCA8 SVEP1

2.08e-04194674421344cc4b601d9745fa72d0af3124dab11d1d27
ToppCellfacs-Brain_Myeloid-Cortex-3m-Myeloid|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAJB13 ECSCR DUSP6 PLEK

2.08e-04194674b31d6361fa939a92a4a3dc63c209ecd3eb514e6a
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibro-meso-mesothelial_cell-Mesothelium|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

AOX1 PLA2G2A ABCA8 SVEP1

2.08e-04194674ce599ed0dc181aea0584e426636de5098f34ebe6
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

AOX1 PLA2G2A ABCA8 SVEP1

2.12e-04195674f54bc4454270ff06e85596f98199372b50d0179f
ToppCellIPF-Stromal-Fibroblast|World / Disease state, Lineage and Cell class

AOX1 PLA2G2A ABCA8 SVEP1

2.12e-041956749c32756edb54f0c211185d9a98073fe01fd1526a
ToppCellcontrol-Myeloid-CD16_Monocytes|control / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

TCF7L2 GRK3 DUSP6 TMPO

2.12e-04195674f398d08a23fdfa6202f73a7aeac3ff4c997fbdfd
ToppCellRA-02._Fibroblast_II|RA / Chamber and Cluster_Paper

AOX1 PLA2G2A ABCA8 SVEP1

2.12e-041956746a02ebbeb3199447ddce64d92d8809436e040eba
ToppCellmild_COVID-19_(asymptomatic)-Non-classical_Monocyte|World / disease group, cell group and cell class (v2)

TCF7L2 GRK3 CHST15 DUSP6

2.12e-04195674eb809331557f8c40de45b1208cbc49b621930a4b
ToppCellCOVID-19_Moderate-Non-classical_Monocyte|COVID-19_Moderate / disease group, cell group and cell class

TCF7L2 GRK3 CHST15 DUSP6

2.16e-04196674256c557fa11414c9d2cbb1fcff33f482ee1c78ac
ToppCellAdult-Immune-monocyte|Adult / Lineage, Cell type, age group and donor

GRK2 GRK3 CHST15 PLEK

2.16e-041966743ef193c5180de3137daf886492e74fc574bc9767
ToppCellIPF-Stromal-Fibroblast|IPF / Disease state, Lineage and Cell class

AOX1 PLA2G2A ABCA8 SVEP1

2.16e-04196674f7ae604ba32b322d86d68b2b54892e7c6ab06c49
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Myeloid-Monocytic-Nonclassical_Monocyte|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TCF7L2 GRK3 CHST15 DUSP6

2.16e-0419667429246378ffb1010fe6858da756ae3d13df2306ba
ToppCellControl-Stromal-Fibroblast|Control / Disease state, Lineage and Cell class

AOX1 PLA2G2A ABCA8 SVEP1

2.16e-041966747ca94477498a84cafcdd9933ee92a6cbde76c70e
Drug1NaPP1

PIK3CB GRIA3 GRIA4

5.50e-0612683CID000004877
Drug8-chloroadenosine

ADK GRK2 GRK3 NRK

6.13e-0640684CID000147569
DrugProgestins

ECSCR UBR4 GNL2 NME1 NNT

8.23e-0692685ctd:D011372
DrugBiM4

GRK2 GRK3 PIK3CB DUSP6 RPS6KA6 FADD PLEK

2.16e-05283687CID000002399
Drug8-azidoadenosine

ADK GRK2 GRK3

2.39e-0519683CID000160751
DrugCeforanide [60925-61-3]; Up 200; 7.6uM; MCF7; HT_HG-U133A

TCF7L2 TECPR2 STK17A RPS6KA6 SVEP1 FARP2

2.57e-051956863309_UP
DrugTocainide hydrochloride; Down 200; 17.4uM; MCF7; HT_HG-U133A

TCF7L2 SAMD9 GRK2 TECPR2 TIGD6 FARP2

2.80e-051986864838_DN
DrugHemicholinium bromide [312-45-8]; Up 200; 7uM; MCF7; HT_HG-U133A

NR2C1 GRK2 GRK3 CAMK2G RPS6KA6 FGF12

2.88e-051996863216_UP
Drughydroxyl radical

AOX1 ZBTB9 TMPO GRIA3 GRIA4 NOS1

3.50e-05206686CID000157350
Drug8-Cl-cAMP

ADK GRK2 GRK3 NRK

4.84e-0567684CID000100299
Drug3-pyridazinol 1-oxide

GRIA3 GRIA4

5.25e-054682CID000574311
Drugamthamine

GRK2 GRK3 NOS1

6.31e-0526683CID000126688
DrugAC1L1GTT

GRK2 GRK3 CAMK2G CCL1 GRIA3 GRIA4

6.94e-05233686CID000003837
DrugGF109203X

GRK2 GRK3 PIK3CB RPS6KA6 TMPO GRIA4 PLEK

7.04e-05341687CID000002396
DrugAC1L1E5T

RPS6KA6 GRIA3 GRIA4 NOS1

7.15e-0574684CID000002653
DrugDiC8

GRK2 GRK3 RPS6KA6 PLEK NOS1

7.62e-05146685CID000001323
DrugAC1L1YEG

GRIA3 GRIA4

8.74e-055682CID000063114
DrugChicago acid

GRIA3 GRIA4

8.74e-055682CID000065740
DrugCHEBI:570577

GRIA3 GRIA4

8.74e-055682CID011334126
Drug1-BCP

GRIA3 GRIA4

8.74e-055682CID000001370
Drugirampanel

GRIA3 GRIA4

8.74e-055682CID003038472
Drugbeta-N-oxalylaminoalanine

GRIA3 GRIA4

8.74e-055682CID000107978
DrugLY395153

GRIA3 GRIA4

8.74e-055682CID000656707
Drug5-h PCA

GRIA3 GRIA4

8.74e-055682CID000129091
DiseaseAnoxemia

ADK NME1 NOS1

5.81e-0533673C0003129
DiseaseHypoxemia

ADK NME1 NOS1

5.81e-0533673C0700292
DiseaseHypoxia

ADK NME1 NOS1

5.81e-0533673C0242184
DiseaseAnoxia

ADK NME1 NOS1

5.81e-0533673C0003130
Diseasephospholipase A2, membrane associated measurement

PLA2G2A ABCA8

2.26e-0410672EFO_0008259
DiseaseSpastic Paraplegia, Hereditary

TECPR2 L1CAM

4.54e-0414672C0037773
DiseaseEndometrioma

NR2C1 NR2C2 PLA2G2A CCL1

5.01e-04161674C0269102
DiseaseEndometriosis

NR2C1 NR2C2 PLA2G2A CCL1

5.01e-04161674C0014175
Diseaseaggressive behaviour measurement, ADHD symptom measurement

TCF7L2 CAMK2G DUSP6

5.05e-0468673EFO_0007826, EFO_0007860
Diseaseimpotence (implicated_via_orthology)

GRK2 NOS1

5.23e-0415672DOID:1875 (implicated_via_orthology)
Diseasecentral nervous system disease (implicated_via_orthology)

GRIA3 GRIA4

5.97e-0416672DOID:331 (implicated_via_orthology)
DiseaseMyocardial Ischemia

TCF7L2 DUSP6 PLA2G2A TMPO

7.00e-04176674C0151744
Diseasebipolar disorder (is_marker_for)

GRK3 L1CAM

8.47e-0419672DOID:3312 (is_marker_for)
DiseaseLeft Ventricle Remodeling

TCF7L2 NOS1

1.04e-0321672C0600520
DiseaseVentricular Remodeling

TCF7L2 NOS1

1.04e-0321672C0600519
Diseaseactivities of daily living score measurement

NOS1 FARP2

1.04e-0321672EFO_0008451
Diseasevenous thromboembolism, plasminogen activator inhibitor 1 measurement

CKAP5 PLEK

1.04e-0321672EFO_0004286, EFO_0004792
Diseaseaggressive behavior

SAMD9 PLEK

1.47e-0325672EFO_0003015
DiseaseAdenoid Cystic Carcinoma

KMT2C ARID4B STAG3L1

1.55e-03100673C0010606
Diseasehypertension (biomarker_via_orthology)

GRK2 GRK3 FADD NOS1

1.79e-03227674DOID:10763 (biomarker_via_orthology)
Diseasecytotoxicity measurement, response to clozapine

CHST15 CCL1

1.98e-0329672EFO_0006952, GO_0097338
DiseaseParkinson's disease (biomarker_via_orthology)

GRK2 GRK3

2.12e-0330672DOID:14330 (biomarker_via_orthology)
Diseasetemporal lobe epilepsy (biomarker_via_orthology)

ADK NOS1

2.26e-0331672DOID:3328 (biomarker_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
RGAFCEAKIKTAKRL

ARID4B

21

Q4LE39
ICSNEGLIFKLKRGK

CCL1

56

P22362
GLIFKLKRGKEACAL

CCL1

61

P22362
DKKCILFRIKGGKQF

GRK3

616

P35626
CIKSLIRKFTCKLFG

CFAP61

26

Q8NHU2
IRKFTCKLFGKLNII

CFAP61

31

Q8NHU2
CIGIDKFGEILKRKA

ADK

106

P55263
SLRFLKREAKLCGFL

CCDC154

236

A6NI56
KREAKLCGFLQKSFL

CCDC154

241

A6NI56
KARTCFVSDLKRGLK

ACTR10

211

Q9NZ32
ERKCLLLKIRGGKQF

GRK2

616

P25098
LRKKLRLTGTKYGCG

AOX1

31

Q06278
EGCKGFFKRSIRKNL

NR2C1

131

P13056
GCKGFFKRSVRKNLT

NR2C2

136

P49116
KKRIAKGTTVARFCG

PGBD4

366

Q96DM1
YKRLEKRGCGTKFLS

PLA2G2A

71

P14555
KKDIRRGIGYLKLIC

ANKAR

306

Q7Z5J8
FLEKLAFRTGKLLKG

GNL2

421

Q13823
CKVVILGSGVRKSFK

KMT2C

4201

Q8NEZ4
GTLFGGEVCKVIKKR

TMPO

676

P42166
NLKKKDRGVGSTLFC

LRRC53

401

A6NM62
TLQKVFGRVKFERKG

DDX60

1236

Q8IY21
GVARVRKSKGKFAFL

GRIA3

721

P42263
GVARVRKSKGKFAFL

GRIA4

711

P48058
FDSFIKRKVISLKGC

OR4X1

81

Q8NH49
VLLILCFIKRSKGGK

L1CAM

1136

P32004
KSGRKFAGQIREKFI

FAM83A

231

Q86UY5
KGGELLDRILKQKCF

RPS6KA6

501

Q9UK32
FKRKVGGLGFLVKER

NOS1

21

P29475
RRAIGFKKLAEAVKF

NOS1

731

P29475
AKCLTGLAVGLRKKF

CKAP5

341

Q14008
GKGGFIRAKLVCKTL

FBH1

546

Q8NFZ0
GFRRKLFKRVKCISC

C16orf96

901

A6NNT2
LVGVVSLRFKCRKSK

ECSCR

141

Q19T08
TELKFLCLGRVGKRK

FADD

21

Q13158
LDKIRGKFKQFCSLL

LTO1

106

Q8WV07
LFFGCTKKIKISRRV

DNAJB13

151

P59910
CVFRVSVRKELKGGK

FAM102A

81

Q5T9C2
FIREGCLHKLTKKGL

FARP2

756

O94887
GLLLKKLKDEGCRAF

DUSP6

116

Q16828
GKGAFSVVRRCVKKT

CAMK2G

21

Q13555
LLKGCKVFVGRFKNR

PABPC4L

161

P0CB38
FISGREIKKRKCLFG

PHF1

316

O43189
KLRFLCTRGDKLFFT

NRK

1541

Q7Z2Y5
GSCKGLRVKKDFLRT

NNT

21

Q13423
LGVFSKVRFCSGRKR

FGF12

46

P61328
RGGKKAKQRLTALFC

TIGD6

201

Q17RP2
KRFEQKGFRLVGLKF

NME1

26

P15531
FFLGKGKRLERLVHK

SAMD9

1481

Q5K651
KCIEGGQKFARKSTR

PLEK

101

P08567
EALIRFGGFRKRKKA

SLCO6A1

56

Q86UG4
RVKCVKALKGLYGNR

STAG3L1

61

P0CL83
ILGNFKSKFGIKRER

PIK3CB

941

P42338
KAARIQCFKGFKLLG

SVEP1

3026

Q4LDE5
ELGRGKFAVVRKCIK

STK17A

66

Q9UEE5
IASCLRKEYAGKRKG

ABCA8

1281

O94911
FLRFKKGKRCSLVFG

CHST15

71

Q7LFX5
CPFSRGKKCLDFRKI

WFDC6

61

Q9BQY6
KECGKAFIRRGNLKE

ZNF540

526

Q8NDQ6
KECGKTFFSLKRIRR

ZNF136

171

P52737
QDGFKLKGATKRLCL

SUSD4

86

Q5VX71
RRKKKCVRYIQGEGS

TCF7L2

481

Q9NQB0
RKDQFKRLIAGCIGK

XPO5

1146

Q9HAV4
TGRFFGGLCLDIKRK

SLC4A5

491

Q9BY07
RVKCVKALKGLYGNR

STAG3L2

61

P0CL84
NRAFACGKVTIKGKR

TECPR2

871

O15040
GKRFGCLCGKRFAVK

ZBTB9

381

Q96C00
SDCGKGFIKKSRLIN

ZNF613

291

Q6PF04
RVKCVKALKGLYGNR

STAG3L3

61

P0CL85
CRKLGGVKKSATFRS

TPD52L3

106

Q96J77
LLGSYKGKKCAFRVI

RPP14

91

O95059
RCKDYQGIKFVKRLG

WDR35

721

Q9P2L0
RKLLLFICGSKEKYR

UBR4

3211

Q5T4S7