Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncytoskeletal motor activity

KIF4A KIF4B MYH6 MYO5A

1.09e-04118424GO:0003774
GeneOntologyMolecularFunctioncytoskeletal protein binding

KIF4A KIF4B MYH6 DMD OFD1 MYO5A ANKRD1 SYNE2 TBCD

3.85e-041099429GO:0008092
GeneOntologyMolecularFunctioniron-sulfur cluster binding

KIF4A KIF4B POLR3F

5.90e-0478423GO:0051536
GeneOntologyMolecularFunctionmetal cluster binding

KIF4A KIF4B POLR3F

7.07e-0483423GO:0051540
GeneOntologyMolecularFunctionhistone H3K4 methyltransferase activity

SETD1A ASH1L

8.01e-0420422GO:0042800
GeneOntologyBiologicalProcesscardiac muscle tissue morphogenesis

PTCD2 MYH6 DSP ANKRD1

1.64e-0577414GO:0055008
GeneOntologyBiologicalProcessmuscle tissue morphogenesis

PTCD2 MYH6 DSP ANKRD1

3.45e-0593414GO:0060415
GeneOntologyBiologicalProcessmicrotubule-based movement

KIF4A KIF4B OFD1 MYO5A TTC21A SYNE2 ASH1L

4.75e-05493417GO:0007018
GeneOntologyBiologicalProcessmuscle organ morphogenesis

PTCD2 MYH6 DSP ANKRD1

4.96e-05102414GO:0048644
GeneOntologyBiologicalProcessmicrotubule-based transport

KIF4A OFD1 MYO5A TTC21A SYNE2

1.39e-04253415GO:0099111
GeneOntologyBiologicalProcessmicrotubule-based process

KIF4A KIF4B OFD1 MYO5A WEE1 TTC21A SYNE2 TBCD ASH1L

1.88e-041058419GO:0007017
GeneOntologyBiologicalProcessmitotic spindle midzone assembly

KIF4A KIF4B

2.10e-0411412GO:0051256
GeneOntologyBiologicalProcessactin filament-based transport

MYO5A SYNE2

2.10e-0411412GO:0099515
GeneOntologyBiologicalProcessventricular cardiac muscle tissue morphogenesis

PTCD2 MYH6 DSP

2.19e-0459413GO:0055010
GeneOntologyBiologicalProcessactin filament-based movement

MYH6 MYO5A DSP SYNE2

2.38e-04153414GO:0030048
GeneOntologyBiologicalProcessmitotic spindle elongation

KIF4A KIF4B

2.51e-0412412GO:0000022
GeneOntologyBiologicalProcesscardiac ventricle development

PTCD2 MYH6 DSP TRIP11

2.89e-04161414GO:0003231
GeneOntologyBiologicalProcessspindle midzone assembly

KIF4A KIF4B

3.46e-0414412GO:0051255
GeneOntologyBiologicalProcessspindle elongation

KIF4A KIF4B

3.46e-0414412GO:0051231
GeneOntologyBiologicalProcesssebaceous gland development

GSDMA ASH1L

3.98e-0415412GO:0048733
GeneOntologyBiologicalProcessanagen

GSDMA MYO5A

4.55e-0416412GO:0042640
GeneOntologyBiologicalProcessventricular cardiac muscle tissue development

PTCD2 MYH6 DSP

4.63e-0476413GO:0003229
GeneOntologyBiologicalProcesstransport along microtubule

KIF4A MYO5A TTC21A SYNE2

6.20e-04197414GO:0010970
GeneOntologyBiologicalProcesscardiac ventricle morphogenesis

PTCD2 MYH6 DSP

7.11e-0488413GO:0003208
GeneOntologyBiologicalProcessstriated muscle cell development

MYH6 DMD ANKRD1

7.35e-0489413GO:0055002
GeneOntologyBiologicalProcessmitotic spindle assembly

KIF4A KIF4B OFD1

8.10e-0492413GO:0090307
GeneOntologyBiologicalProcesscardiac chamber development

PTCD2 MYH6 DSP TRIP11

8.16e-04212414GO:0003205
GeneOntologyBiologicalProcessskin development

GSDMA MYO5A DSP CD109 ASH1L

8.26e-04373415GO:0043588
GeneOntologyCellularComponentsupramolecular fiber

KIF4A KIF4B MYH6 CDK5RAP3 DMD MYO5A DSP NBR1 ANKRD1 SYNE2 TBCD

1.49e-0511794211GO:0099512
GeneOntologyCellularComponentsupramolecular polymer

KIF4A KIF4B MYH6 CDK5RAP3 DMD MYO5A DSP NBR1 ANKRD1 SYNE2 TBCD

1.58e-0511874211GO:0099081
GeneOntologyCellularComponentsarcomere

MYH6 DMD NBR1 ANKRD1 SYNE2

1.37e-04249425GO:0030017
GeneOntologyCellularComponentmyofibril

MYH6 DMD NBR1 ANKRD1 SYNE2

2.10e-04273425GO:0030016
GeneOntologyCellularComponentcontractile muscle fiber

MYH6 DMD NBR1 ANKRD1 SYNE2

2.77e-04290425GO:0043292
GeneOntologyCellularComponentI band

MYH6 DMD ANKRD1 SYNE2

3.39e-04166424GO:0031674
GeneOntologyCellularComponentfilopodium membrane

DMD SYNE2

8.08e-0421422GO:0031527
GeneOntologyCellularComponentintermediate filament cytoskeleton

DMD MYO5A DSP SYNE2

1.88e-03263424GO:0045111
GeneOntologyCellularComponentpolymeric cytoskeletal fiber

KIF4A KIF4B CDK5RAP3 DMD MYO5A DSP TBCD

1.92e-03899427GO:0099513
GeneOntologyCellularComponentfilopodium

DMD MYO5A SYNE2

1.93e-03123423GO:0030175
HumanPhenoEMG abnormality

MYH6 DMD NALCN DSP SMCHD1 ANKRD1 SYNE2

3.56e-05293187HP:0003457
HumanPhenoLipodystrophy

MYH6 DMD DSP ANKRD1 SYNE2

5.88e-05127185HP:0009125
HumanPhenoMyopathy

MYH6 DMD NALCN DSP SMCHD1 ANKRD1 SYNE2

9.46e-05341187HP:0003198
HumanPhenoThromboembolic stroke

MYH6 DMD DSP ANKRD1

1.13e-0475184HP:0001727
HumanPhenoLipoatrophy

MYH6 DMD DSP ANKRD1

1.39e-0479184HP:0100578
MousePhenoincreased dendritic spine number

KIF4A KIF4B

2.04e-053372MP:0021019
MousePhenodecreased cardiac stroke volume

MYH6 CDK5RAP3 DMD

6.60e-0530373MP:0011952
DomainSpectrin_repeat

DMD DSP SYNE2

3.71e-0529423IPR002017
DomainSpectrin/alpha-actinin

DMD DSP SYNE2

5.01e-0532423IPR018159
DomainSPEC

DMD DSP SYNE2

5.01e-0532423SM00150
DomainCH

EHBP1 DMD SYNE2

4.19e-0465423SM00033
DomainCH

EHBP1 DMD SYNE2

5.21e-0470423PF00307
Domain-

EHBP1 DMD SYNE2

5.43e-04714231.10.418.10
DomainPost-SET_dom

SETD1A ASH1L

5.81e-0416422IPR003616
DomainPostSET

SETD1A ASH1L

5.81e-0416422SM00508
DomainPOST_SET

SETD1A ASH1L

5.81e-0416422PS50868
DomainCH

EHBP1 DMD SYNE2

5.89e-0473423PS50021
DomainCH-domain

EHBP1 DMD SYNE2

6.38e-0475423IPR001715
DomainZF_ZZ_2

DMD NBR1

7.38e-0418422PS50135
DomainZF_ZZ_1

DMD NBR1

7.38e-0418422PS01357
DomainZZ

DMD NBR1

7.38e-0418422PF00569
DomainZnf_ZZ

DMD NBR1

8.24e-0419422IPR000433
DomainZnF_ZZ

DMD NBR1

8.24e-0419422SM00291
Domain-

TEX11 DNAJC7 TTC21A GPS1

1.18e-032074241.25.40.10
DomainActinin_actin-bd_CS

DMD SYNE2

1.21e-0323422IPR001589
DomainACTININ_2

DMD SYNE2

1.21e-0323422PS00020
DomainACTININ_1

DMD SYNE2

1.21e-0323422PS00019
DomainSpectrin

DMD SYNE2

1.21e-0323422PF00435
DomainTPR-like_helical_dom

TEX11 DNAJC7 TTC21A GPS1

1.82e-03233424IPR011990
DomainTPR

TEX11 DNAJC7 TTC21A

3.04e-03129423SM00028
DomainMYOSIN_MOTOR

MYH6 MYO5A

3.30e-0338422PS51456
DomainMyosin_head

MYH6 MYO5A

3.30e-0338422PF00063
DomainMyosin_head_motor_dom

MYH6 MYO5A

3.30e-0338422IPR001609
DomainMYSc

MYH6 MYO5A

3.30e-0338422SM00242
DomainTPR_repeat

TEX11 DNAJC7 TTC21A

3.31e-03133423IPR019734
DomainSET

SETD1A ASH1L

3.83e-0341422PF00856
DomainKinesin_motor_CS

KIF4A KIF4B

3.83e-0341422IPR019821
DomainKinesin-like_fam

KIF4A KIF4B

4.20e-0343422IPR027640
DomainKINESIN_MOTOR_1

KIF4A KIF4B

4.40e-0344422PS00411
Domain-

KIF4A KIF4B

4.40e-03444223.40.850.10
DomainKinesin_motor_dom

KIF4A KIF4B

4.40e-0344422IPR001752
DomainKinesin

KIF4A KIF4B

4.40e-0344422PF00225
DomainKISc

KIF4A KIF4B

4.40e-0344422SM00129
DomainKINESIN_MOTOR_2

KIF4A KIF4B

4.40e-0344422PS50067
DomainSET

SETD1A ASH1L

4.80e-0346422SM00317
DomainSET_dom

SETD1A ASH1L

5.65e-0350422IPR001214
DomainSET

SETD1A ASH1L

5.65e-0350422PS50280
DomainTPR_8

DNAJC7 TTC21A

6.33e-0353422PF13181
Pubmed

ALS/FTD-causing mutation in cyclin F causes the dysregulation of SFPQ.

RPL10A KRI1 GSDMA SETD1A KIF4B DNAJC7 SNRPA WEE1 GPS1

5.96e-0862443933729478
Pubmed

Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.

RPL10A KRI1 KIF4A UBE2O DNAJC7 SNRPA USO1 DSP NBR1 ERC1 SMCHD1 SYNE2

9.34e-081415431228515276
Pubmed

HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.

KIF4A DMD DNAJC7 SNRPA DSP TRIP11 ERC1 SMCHD1 SYNE2

2.94e-0775443935906200
Pubmed

Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.

RPL10A IST1 GSDMA UBE2O CDK5RAP3 DNAJC7 USO1 DSP SYNE2 TBCD GPS1

6.00e-071367431132687490
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

EHBP1 PLEKHG1 OFD1 USO1 DSP TRIP11 WEE1 ERC1 SYNE2

8.88e-0786143936931259
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

SLC44A2 MYH6 DMD DNAJC7 MYO5A DSP ERC1 SMCHD1 SYNE2 GPS1 ASH1L

1.01e-061442431135575683
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

RPL10A KRI1 KIF4A UBE2O MYO5A DSP SMCHD1 SYNE2

1.20e-0665343822586326
Pubmed

KIF4 regulates neuronal morphology and seizure susceptibility via the PARP1 signaling pathway.

KIF4A KIF4B

1.49e-06243236482480
Pubmed

KIF4 regulates midzone length during cytokinesis.

KIF4A KIF4B

1.49e-06243221565503
Pubmed

Whole genome expression microarray reveals novel roles for Kif4 in monocyte/macrophage cells.

KIF4A KIF4B

1.49e-06243231486502
Pubmed

Assignment of the kinesin family member 4 genes (KIF4A and KIF4B) to human chromosome bands Xq13.1 and 5q33.1 by in situ hybridization.

KIF4A KIF4B

1.49e-06243210773663
Pubmed

A novel microtubule-based motor protein (KIF4) for organelle transports, whose expression is regulated developmentally.

KIF4A KIF4B

1.49e-0624327929562
Pubmed

The multiple functions of kinesin-4 family motor protein KIF4 and its clinical potential.

KIF4A KIF4B

1.49e-06243230081192
Pubmed

Missense Pathogenic variants in KIF4A Affect Dental Morphogenesis Resulting in X-linked Taurodontism, Microdontia and Dens-Invaginatus.

KIF4A KIF4B

1.49e-06243231616463
Pubmed

Structural basis for the ATP-induced isomerization of kinesin.

KIF4A KIF4B

1.49e-06243223500491
Pubmed

Chromokinesin Kif4 promotes proper anaphase in mouse oocyte meiosis.

KIF4A KIF4B

1.49e-06243231067151
Pubmed

Kif4 regulates the expression of VEGFR1 through the PI3K/Akt signaling pathway in RAW264.7 monocytes/macrophages.

KIF4A KIF4B

1.49e-06243228350061
Pubmed

Binding of murine leukemia virus Gag polyproteins to KIF4, a microtubule-based motor protein.

KIF4A KIF4B

1.49e-0624329658142
Pubmed

Cellular motor protein KIF-4 associates with retroviral Gag.

KIF4A KIF4B

1.49e-06243210559369
Pubmed

Kif4 interacts with EB1 and stabilizes microtubules downstream of Rho-mDia in migrating fibroblasts.

KIF4A KIF4B

1.49e-06243224658398
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

RPL10A EHBP1 IST1 KIF4A UBE2O DSP TRIP11 ERC1 SMCHD1

1.74e-0693443933916271
Pubmed

Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.

IST1 UBE2O CDK5RAP3 DNAJC7 SNRPA TBCD GPS1 ASH1L

1.79e-0668943836543142
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

RPL10A KRI1 GSDMA TMA16 SNRPA MYO5A DSP ERC1 SMCHD1 CD109

2.37e-061257431036526897
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

KRI1 DMD OFD1 DNAJC7 MYO5A DSP NBR1 ERC1 SYNE2

4.47e-06104943927880917
Pubmed

Dystrophin and calcium current are decreased in cardiomyocytes expressing Cre enzyme driven by αMHC but not TNT promoter.

MYH6 DMD

4.48e-06343231857666
Pubmed

Identification of the human homologue of mouse KIF4, a kinesin superfamily motor protein.

KIF4A KIF4B

4.48e-06343210978527
Pubmed

Participation of myosin Va and Pka type I in the regeneration of neuromuscular junctions.

DMD MYO5A

4.48e-06343222815846
Pubmed

KIF4 motor regulates activity-dependent neuronal survival by suppressing PARP-1 enzymatic activity.

KIF4A KIF4B

4.48e-06343216630823
Pubmed

CircKIF4A enhances osteosarcoma proliferation and metastasis by sponging MiR-515-5p and upregulating SLC7A11.

KIF4A KIF4B

4.48e-06343235579738
Pubmed

Tumor formation via loss of a molecular motor protein.

KIF4A KIF4B

4.48e-06343216890532
Pubmed

KIF4 mediates anterograde translocation and positioning of ribosomal constituents to axons.

KIF4A KIF4B

4.48e-06343219158085
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

KIF4A SETD1A UBE2O DNAJC7 DSP ERC1 SMCHD1

4.63e-0654943738280479
Pubmed

Compartmentalization of the SUMO/RNF4 pathway by SLX4 drives DNA repair.

KIF4A GSDMA DSP SMCHD1 NAB1 POLR3F

4.96e-0635743637059091
Pubmed

Interactomes of Glycogen Synthase Kinase-3 Isoforms.

UBE2O OFD1 USO1 NBR1 ERC1

5.97e-0620943536779422
Pubmed

Transcription factor Foxp3 and its protein partners form a complex regulatory network.

KRI1 KIF4A KIF4B SNRPA USO1 SMCHD1

6.09e-0637043622922362
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

RPL10A MYH6 UBE2O DMD MYO5A USO1 DSP TRIP11 ERC1 TTC21A

7.46e-061431431037142655
Pubmed

The deubiquitinase USP7 stabilizes Maf proteins to promote myeloma cell survival.

KRI1 UBE2O TMA16 SNRPA GPS1

7.66e-0622043531822558
Pubmed

Dilated Cardiomyopathy Overview

MYH6 DMD ANKRD1

8.52e-063243320301486
Pubmed

Kinesin KIF4 regulates intracellular trafficking and stability of the human immunodeficiency virus type 1 Gag polyprotein.

KIF4A KIF4B

8.94e-06443218684836
Pubmed

Localization of dystrophin gene transcripts during mouse embryogenesis.

MYH6 DMD

8.94e-0644321429837
Pubmed

Kif4 Is Essential for Mouse Oocyte Meiosis.

KIF4A KIF4B

8.94e-06443228125646
Pubmed

Identification of NAB1, a repressor of NGFI-A- and Krox20-mediated transcription.

DMD NAB1

8.94e-0644327624335
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

RPL10A KRI1 PLEKHG1 UBE2O CDK5RAP3 OFD1 DNAJC7 MYO5A NBR1 SYNE2

1.04e-051487431033957083
Pubmed

Proteomic and Biochemical Comparison of the Cellular Interaction Partners of Human VPS33A and VPS33B.

PLEKHG1 OFD1 TRIP11 ERC1 SYNE2

1.45e-0525143529778605
Pubmed

Cardiac ankyrin repeat protein is a marker of skeletal muscle pathological remodelling.

DMD ANKRD1

1.49e-05543219143834
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

IST1 UBE2O DNAJC7 MYO5A DSP TRIP11 ERC1 HPF1 ASH1L

2.26e-05128543935914814
Pubmed

High-sensitivity profiling of SARS-CoV-2 noncoding region-host protein interactome reveals the potential regulatory role of negative-sense viral RNA.

RPL10A TMA16 SNRPA DSP GPS1 POLR3F

2.33e-0546943637314180
Pubmed

BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.

RPL10A EHBP1 CDK5RAP3 DNAJC7 USO1 DSP ERC1

2.40e-0570843739231216
Pubmed

MYC multimers shield stalled replication forks from RNA polymerase.

RPL10A KRI1 KIF4A TMA16 DNAJC7 DSP SMCHD1 ANKRD1

2.49e-0598943836424410
Pubmed

Unusual chromatin status and organization of the inactive X chromosome in murine trophoblast giant cells.

KIF4A KIF4B

3.12e-05743223362347
Pubmed

Kinesin family in murine central nervous system.

KIF4A KIF4B

3.12e-0574321447303
Pubmed

Genetic mapping in the mouse of Kif4, a gene encoding a kinesin-like motor protein.

KIF4A KIF4B

3.12e-0574329196009
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

RPL10A OFD1 DNAJC7 SNRPA MYO5A DSP SMCHD1 SYNE2

3.19e-05102443824711643
Pubmed

Skirting the pitfalls: a clear-cut nomenclature for H3K4 methyltransferases.

SETD1A ASH1L

4.16e-05843223130995
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

RPL10A KRI1 UBE2O DNAJC7 SNRPA USO1 DSP NBR1 SMCHD1

5.07e-05142543930948266
Pubmed

Human transcription factor protein interaction networks.

RPL10A KRI1 SETD1A UBE2O OFD1 DNAJC7 MYO5A SMCHD1 SYNE2

5.19e-05142943935140242
Pubmed

Interactions with LC3 and polyubiquitin chains link nbr1 to autophagic protein turnover.

UBE2O NBR1

5.35e-05943219427866
Pubmed

Generation and characterization of a Myh6-driven Cre knockin mouse line.

MYH6 DSP

6.68e-051043234542814
Pubmed

Contribution of epigenetic landscapes and transcription factors to X-chromosome reactivation in the inner cell mass.

KIF4A KIF4B

6.68e-051043229101321
Pubmed

Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis.

EHBP1 CDK5RAP3 DSP TRIP11 ERC1 SYNE2

6.74e-0556843637774976
Pubmed

The human cytoplasmic dynein interactome reveals novel activators of motility.

IST1 KRI1 PLEKHG1 OFD1 DNAJC7 DSP ERC1

7.78e-0585343728718761
Pubmed

Defining the membrane proteome of NK cells.

RPL10A KIF4A CDK5RAP3 OFD1 DNAJC7 MYO5A USO1 NBR1

8.05e-05116843819946888
Pubmed

Cardiac disease and arrhythmogenesis: Mechanistic insights from mouse models.

MYH6 DSP

8.15e-051143227766308
Pubmed

Functional analysis of human microtubule-based motor proteins, the kinesins and dyneins, in mitosis/cytokinesis using RNA interference.

KIF4A KIF4B

8.15e-051143215843429
Pubmed

Characterization of nuclear factors modulating the apolipoprotein D promoter during growth arrest: implication of PARP-1, APEX-1 and ERK1/2 catalytic activities.

KIF4A KIF4B

8.15e-051143220493910
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

DNAJC7 USO1 DSP TRIP11 WEE1 ERC1

8.16e-0558843638580884
Pubmed

Exome sequencing reveals pathogenic mutations in 91 strains of mice with Mendelian disorders.

GSDMA MYO5A DSP

9.89e-057243325917818
Pubmed

Molecular Characterization of the Oncogene BTF3 and Its Targets in Colorectal Cancer.

RPL10A IST1 KIF4A KIF4B MYO5A DSP

1.15e-0462643633644029
Pubmed

Dynamic patterns of histone H3 lysine 4 methyltransferases and demethylases during mouse preimplantation development.

SETD1A ASH1L

1.15e-041343224619213
Pubmed

A novel LZAP-binding protein, NLBP, inhibits cell invasion.

RPL10A CDK5RAP3

1.15e-041343220164180
Pubmed

The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.

RPL10A UBE2O DNAJC7 SNRPA USO1 GPS1

1.27e-0463843633239621
Pubmed

Mapping the MOB proteins' proximity network reveals a unique interaction between human MOB3C and the RNase P complex.

KIF4A DNAJC7 MYO5A USO1 DSP

1.30e-0439943537536630
Pubmed

c-Abl tyrosine kinase regulates cardiac growth and development.

MYH6 ANKRD1

1.35e-041443220080568
Pubmed

Loss of mXinalpha, an intercalated disk protein, results in cardiac hypertrophy and cardiomyopathy with conduction defects.

MYH6 DSP

1.35e-041443217766470
Pubmed

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.

UBE2O DNAJC7 USO1 NBR1 ERC1 TBCD GPS1

1.44e-0494243731073040
Pubmed

ZZW-115-dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents.

IST1 KIF4A SNRPA MYO5A SMCHD1 CD109

1.53e-0466043632780723
Pubmed

Large-scale mapping of human protein-protein interactions by mass spectrometry.

KIF4A CDK5RAP3 SNRPA USO1 DSP WEE1 ERC1 GPS1

1.55e-04128443817353931
Pubmed

Golgi disruption and early embryonic lethality in mice lacking USO1.

USO1 TRIP11

1.55e-041543223185636
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

KIF4A KIF4B UBE2O MYO5A TRIP11 ERC1 SYNE2

1.65e-0496343728671696
Pubmed

Loss of TRIM31 promotes breast cancer progression through regulating K48- and K63-linked ubiquitination of p53.

RPL10A TMA16 SNRPA USO1 WDR87

1.67e-0442143534650049
Pubmed

In silico APC/C substrate discovery reveals cell cycle-dependent degradation of UHRF1 and other chromatin regulators.

RPL10A KRI1 UBE2O TMA16 DNAJC7 SNRPA SMCHD1

1.73e-0497143733306668
Pubmed

A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.

RPL10A KRI1 UBE2O DMD SMCHD1 GPS1 CD109

1.77e-0497443728675297
Pubmed

Gene essentiality and synthetic lethality in haploid human cells.

IST1 SETD1A UBE2O ERC1

1.85e-0422943426472760
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

EHBP1 OFD1 TRIP11 WEE1 ERC1 TTC21A TBCD GPS1

1.88e-04132143827173435
Pubmed

PPARγ Interaction with UBR5/ATMIN Promotes DNA Repair to Maintain Endothelial Homeostasis.

RPL10A DNAJC7 DSP

1.92e-049043330699358
Pubmed

USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.

KRI1 DMD MYO5A DSP

2.01e-0423443436243803
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

RPL10A KIF4A GSDMA SETD1A SNRPA MYO5A DSP SMCHD1

2.21e-04135343829467282
Pubmed

Myocardial overexpression of ANKRD1 causes sinus venosus defects and progressive diastolic dysfunction.

MYH6 ANKRD1

2.26e-041843231688894
Pubmed

Human Immunodeficiency Virus Type 1 Vpr Mediates Degradation of APC1, a Scaffolding Component of the Anaphase-Promoting Complex/Cyclosome.

UBE2O OFD1 NBR1 ERC1

2.28e-0424243434011540
Pubmed

Myocardial-specific ablation of Jumonji and AT-rich interaction domain-containing 2 (Jarid2) leads to dilated cardiomyopathy in mice.

MYH6 ANKRD1

2.52e-041943230700554
Pubmed

Proximity interactions among centrosome components identify regulators of centriole duplication.

GSDMA UBE2O OFD1

2.70e-0410143324613305
Pubmed

BAC contig from a 3-cM region of mouse chromosome 11 surrounding Brca1.

DNAJC7 NBR1

3.09e-042143211013085
Pubmed

DOT1L regulates dystrophin expression and is critical for cardiac function.

MYH6 DMD

3.09e-042143221289070
Pubmed

Prokineticin receptor-1 signaling promotes Epicardial to Mesenchymal Transition during heart development.

MYH6 DMD

3.09e-042143227150455
Pubmed

The nuclear interactome of DYRK1A reveals a functional role in DNA damage repair.

KRI1 DNAJC7 ERC1

3.11e-0410643331024071
Pubmed

RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.

EHBP1 UBE2O TRIP11 NBR1

3.13e-0426343434702444
Pubmed

A new role for the calcineurin/NFAT pathway in neonatal myosin heavy chain expression via the NFATc2/MyoD complex during mouse myogenesis.

MYH6 DMD

3.40e-042243224301466
Pubmed

Noncoding RNA MaIL1 is an integral component of the TLR4-TRIF pathway.

WEE1 CD109

3.40e-042243232241891
Pubmed

CHK2-BRCA1 tumor-suppressor axis restrains oncogenic Aurora-A kinase to ensure proper mitotic microtubule assembly.

RPL10A SETD1A USO1 DSP ERC1

3.49e-0449443526831064
Pubmed

The DNA sequence and analysis of human chromosome 14.

CCDC175 TRIP11 SYNE2

3.56e-0411143312508121
InteractionH3C1 interactions

RPL10A KRI1 KIF4A SETD1A DNAJC7 SNRPA DSP WDR87 SMCHD1 HPF1 ASH1L

2.07e-069014311int:H3C1
InteractionTTN interactions

RPL10A KRI1 MYH6 DSP WEE1 NBR1 ANKRD1

3.01e-06299437int:TTN
InteractionKRT8 interactions

PLEKHG1 DMD OFD1 DSP TRIP11 NBR1 ERC1

3.74e-05441437int:KRT8
InteractionPEG10 interactions

UBE2O DNAJC7 SNRPA SMCHD1

7.62e-05106434int:PEG10
InteractionOFD1 interactions

EHBP1 PLEKHG1 OFD1 DNAJC7 DSP ERC1

8.89e-05347436int:OFD1
InteractionPRNP interactions

IST1 UBE2O CDK5RAP3 DMD DNAJC7 SNRPA USO1 TBCD GPS1 ASH1L

1.27e-0411584310int:PRNP
InteractionB3GAT1 interactions

EHBP1 CDK5RAP3 USO1 TRIP11 NBR1 SYNE2

1.40e-04377436int:B3GAT1
InteractionDNAJB6 interactions

KRI1 UBE2O CDK5RAP3 DNAJC7 USO1 ANKRD1

1.44e-04379436int:DNAJB6
InteractionSIRT7 interactions

RPL10A KRI1 KIF4A UBE2O MYO5A DSP SMCHD1 SYNE2

1.53e-04744438int:SIRT7
InteractionPCNT interactions

SETD1A OFD1 DNAJC7 USO1 TRIP11

1.56e-04241435int:PCNT
InteractionMAFB interactions

KRI1 UBE2O TMA16 SNRPA GPS1

1.72e-04246435int:MAFB
InteractionNAA40 interactions

RPL10A EHBP1 IST1 KIF4A UBE2O DSP TRIP11 ERC1 SMCHD1

1.83e-04978439int:NAA40
InteractionBICD1 interactions

IST1 KRI1 PLEKHG1 OFD1 ERC1

1.85e-04250435int:BICD1
InteractionTNIP1 interactions

RPL10A GSDMA TMA16 DMD OFD1 SNRPA MYO5A DSP NBR1 CD109

1.91e-0412174310int:TNIP1
InteractionGJA1 interactions

EHBP1 MYH6 CDK5RAP3 USO1 TRIP11 NBR1 SYNE2

2.13e-04583437int:GJA1
InteractionFBXO42 interactions

RPL10A USO1 DSP TRIP11 ERC1

2.18e-04259435int:FBXO42
InteractionCLEC4D interactions

CDK5RAP3 MYO5A TRIP11 NBR1 SYNE2

2.26e-04261435int:CLEC4D
InteractionTRRAP interactions

KIF4A DMD OFD1 DNAJC7 SNRPA DSP NBR1 SMCHD1

2.31e-04790438int:TRRAP
InteractionLHX5 interactions

DMD SYNE2

2.42e-0411432int:LHX5
InteractionKRT18 interactions

UBE2O OFD1 DSP NBR1 ERC1 SMCHD1

2.48e-04419436int:KRT18
InteractionKIF23 interactions

RPL10A PTCD2 KRI1 UBE2O DMD MYO5A DSP ERC1 CD109

2.71e-041031439int:KIF23
InteractionHSF1 interactions

RPL10A KIF4A DSP TRIP11 ERC1 SMCHD1 SYNE2

2.78e-04609437int:HSF1
CytobandXq13.1

KIF4A TEX11

9.40e-0448432Xq13.1
CytobandEnsembl 112 genes in cytogenetic band chr17q21

GSDMA CDK5RAP3 DNAJC7 NBR1

9.99e-04473434chr17q21
CytobandEnsembl 112 genes in cytogenetic band chr17q25

UBE2O TBCD GPS1

3.00e-03307433chr17q25
Cytoband17q25.3

TBCD GPS1

4.08e-0310143217q25.3
GeneFamilyZinc fingers ZZ-type|Lysine acetyltransferases

DMD NBR1

2.77e-041825291
GeneFamilyZinc fingers C2H2-type|Lysine methyltransferases|PR/SET domain family

SETD1A ASH1L

1.00e-0334252487
GeneFamilyKinesins|Pleckstrin homology domain containing

KIF4A KIF4B

1.83e-0346252622
GeneFamilyX-linked mental retardation|Angiotensin receptors

KIF4A DMD

2.42e-0353252103
GeneFamilyTetratricopeptide repeat domain containing|Bardet-Biedl syndrome associated|BBSome

DNAJC7 TTC21A

1.09e-02115252769
ToppCellTCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Classical-8|TCGA-Thryoid / Sample_Type by Project: Shred V9

PLEKHG1 DMD NAB1 CD109

2.07e-0516843400646601548b0fee42ae16bfa5e93603bc7c5129
ToppCelldroplet-Limb_Muscle-MUSCLE-30m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRIP11 SMCHD1 SYNE2 ASH1L

2.59e-0517843401dafd19de04eff459253eaa9a35debf8f3deedf
ToppCellCOVID-19-kidney-PLVAP+EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

PLEKHG1 SYNE2 TBCD CD109

2.71e-05180434493cf8d1a8f2a1ed2672f394a0338b110fd81d88
ToppCellCalu_3-infected|Calu_3 / Cell line, Condition and Strain

DSP SMCHD1 SYNE2 ASH1L

2.89e-051834348f7f5000645f24f20a8d7700c4df1f8953a1780b
ToppCellCOVID-19-Heart-CM_1|COVID-19 / Disease (COVID-19 only), tissue and cell type

MYH6 DMD NALCN ANKRD1

2.95e-05184434e737f0f14c49b07bbb04a165083ac32210bc5690
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DSP TRIP11 SYNE2 ASH1L

3.41e-0519143460c986d2dcbc19d9338c03da6cb5e1d92fd48f8e
ToppCelldroplet-Heart-nan-3m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EHBP1 MYH6 DSP ANKRD1

3.41e-0519143497fb4232417a39801e87725755fd16a57c250209
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DSP TRIP11 SYNE2 ASH1L

3.41e-0519143409db184cb90fe282a14474d7217068c58092c6f8
ToppCelldroplet-Heart-nan-3m-Mesenchymal-cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EHBP1 MYH6 DSP ANKRD1

3.41e-0519143464070a309d7e3f6001272409ab9ce206d0e7d73f
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DSP TRIP11 SYNE2 ASH1L

3.41e-05191434973117730d6ba5f127e7a0bfabfd0ff2ca7ac131
ToppCelldroplet-Heart-nan-24m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EHBP1 MYH6 DSP ANKRD1

3.48e-051924341a0c25106ae08eac912a4edd5fc1a3ee776f69c2
ToppCelldroplet-Heart-nan-24m-Mesenchymal-cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EHBP1 MYH6 DSP ANKRD1

3.48e-05192434f6a4e348406a852ace9fb21db8fbdff539217645
ToppCellCOVID-19-kidney-Glomerular_EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

SLC44A2 PLEKHG1 SYNE2 CD109

3.63e-05194434660535b492445063d965095a50e1e299ce04c50a
ToppCelldroplet-Limb_Muscle-MUSCLE|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRIP11 WEE1 ERC1 ASH1L

3.63e-05194434e3d63874111d1e8da3977329426e4dcf68d6de87
ToppCellCOVID-19-kidney-PLVAP+EC|kidney / Disease (COVID-19 only), tissue and cell type

PLEKHG1 SMCHD1 TBCD CD109

3.70e-05195434a436483fec137584611f86b7a498a4dc2aa19cd3
ToppCell(1)_T_cells-(1)_T_CD4_naive|(1)_T_cells / Spleen cell shreds - cell class (v1) and cell subclass (v1)

TRIP11 ERC1 SMCHD1 ASH1L

3.70e-05195434d3fa551bc6f5ee5890af1040415e61ecd5d46201
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

PLEKHG1 OFD1 SMCHD1 SYNE2

3.77e-05196434c225c8eb2fe9a10f0cf574c7d8b6206887aac2df
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CCDC175 DMD TTC21A SYNE2

3.85e-0519743474a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-lymphocytic|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

RPL10A OFD1 SMCHD1 SYNE2

3.93e-051984345024d43b4cf7dea305ed911f1e123ca7fd44e990
ToppCellCOVID-19_Moderate|World / disease group, cell group and cell class

DSP SMCHD1 SYNE2 ASH1L

4.00e-05199434952fac67588ad5676f5939e3c7f8bac803c27064
ToppCellSepsis-ICU-SEP-Lymphocyte-T/NK-MAIT|ICU-SEP / Disease, condition lineage and cell class

EHBP1 TIGD7 OFD1 NAB1

4.00e-051994342f10622319c6146dfed8cfe3844180c1e1d56e94
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW12-Mesenchymal-Unfolded_protein_responsible_cell|GW12 / Sample Type, Dataset, Time_group, and Cell type.

KRI1 SLC26A6 TTC21A CD109

4.08e-052004346b7314c425f6b40f1301dd39cc02b0436e96a2ec
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW12-Mesenchymal|GW12 / Sample Type, Dataset, Time_group, and Cell type.

KRI1 SLC26A6 TTC21A CD109

4.08e-05200434be83f442179ba4217d12f0458059586ff3130991
ToppCellRV-03._Atrial_Cardiomyocyte|RV / Chamber and Cluster_Paper

MYH6 DMD WEE1

1.42e-0410543349e16b11f16e83a7d17d162c14bce991201bcc2a
ToppCellLV-03._Atrial_Cardiomyocyte|LV / Chamber and Cluster_Paper

MYH6 DMD ANKRD1

2.11e-041204333b77bd0e3630cdd45001cecf5e47660a90ebc92e
ToppCell3'_v3-bone_marrow-Lymphocytic_T_CD4-T_CD4/CD8|bone_marrow / Manually curated celltypes from each tissue

SMCHD1 SYNE2 ASH1L

2.16e-0412143319333a660800b583fa27b495c1f7828e6636a257
ToppCellfacs-Heart-RV-24m-Myeloid-macrophage|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KRI1 TMA16 DSP

2.99e-041354331fe684ed5913ae757ad6befbbe12d1bee481dd12
ToppCellfacs-Heart-RV-24m-Myeloid-macrophage|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KRI1 TMA16 DSP

2.99e-0413543399e7ac9b1139fe4ff036f6f048a8f1cc514c1fb9
ToppCell(08)_Brush+PNEC-(2)_GFP_FOXI1|(08)_Brush+PNEC / shred by cell type by condition

TRIP11 SYNE2 ASH1L

3.18e-04138433817e3f639604ea95adae01e8685ffaa2e0aff7a8
ToppCellPBMC-Control-Lymphocyte-B-B_cell-B_naive-B_activate-7|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PLEKHG1 DMD DSP

3.18e-0413843376be06136c83c167cedece7515228ed4d29dd1f0
ToppCellLA-15._Ventricular_Cardiomyocyte_III|World / Chamber and Cluster_Paper

MYH6 DMD ANKRD1

3.25e-041394339e2a84d5ed7232b70eadbba754d9ca13f2d50fe9
ToppCellsevere_COVID-19-B_cell|World / disease group, cell group and cell class (v2)

PTCD2 PLEKHG1 TMA16

3.53e-0414343328b0e168126a9fe60541dc12bfab385b7a0a2342
ToppCellsevere_COVID-19-B_cell|severe_COVID-19 / disease group, cell group and cell class (v2)

PTCD2 PLEKHG1 TMA16

3.61e-04144433c7f696e55e2d959c58ec32640c71ef86ee25203c
ToppCellLA-15._Ventricular_Cardiomyocyte_III|LA / Chamber and Cluster_Paper

MYH6 DMD ANKRD1

3.83e-041474338970eb6b82589f39439c61a57d999661ec8342de
ToppCell3'_v3-Lung-Lymphocytic_B-Naive_B_cells|Lung / Manually curated celltypes from each tissue

PLEKHG1 DMD DSP

4.39e-041544332b7d7f09c75bbc22de1358fc44b8ad5d3f656617
ToppCell10x5'-bone_marrow-Lymphocytic_T_CD4-T_CD4/CD8|bone_marrow / Manually curated celltypes from each tissue

KIF4B SMCHD1 SYNE2

4.56e-041564331545169694f686d28648a68b552c2ae606599d66
ToppCell10x5'-blood-Lymphocytic_T_CD4-T_CD4/CD8|blood / Manually curated celltypes from each tissue

SMCHD1 SYNE2 ASH1L

5.09e-04162433b4535bcb3f469bc139e73f1122f4070013e5a1de
ToppCellPBMC-Mild-Lymphocyte-B-B_cell-B_naive-B_naive-13|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PLEKHG1 DMD DSP

5.09e-0416243328b3a6ae5519a267eefb70436d3190a387d027b9
ToppCellfacs-Pancreas-Exocrine-18m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GSDMA MYO5A USO1

5.18e-04163433132aece9c79499b4bb3c2bde68d3d7202e1d8772
ToppCellfacs-Heart-LA-18m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCDC175 MYH6 ANKRD1

5.37e-0416543395866f7cc6eb1bb51a034a104a0eb2a53b0256f2
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_B-B_naive-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

PLEKHG1 DMD TTC21A

5.37e-041654338003fd2aa3f5c9d0e99054af4ad2d79a4a3c4829
ToppCellfacs-Heart-LA-18m-Mesenchymal-atrial_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCDC175 MYH6 ANKRD1

5.37e-04165433f8bfe336b9a4460b9349c01acd0bd3167812662f
ToppCelldroplet-Liver-Npc-18m-Myeloid-plasmacytoid_dendritic_cells|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC44A2 DNAJC7 MYO5A

5.56e-04167433a66552667aa6e8992c159df27a57c2e8ae14a9ce
ToppCellPND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYH6 DMD SLC26A6

5.56e-0416743391b14df450bfb6a2b406c88f8c75cd51eeb9e82b
ToppCelldroplet-Liver-Npc-18m-Myeloid-plasmacytoid_dendritic_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC44A2 DNAJC7 MYO5A

5.56e-041674331248f809afbcccb42ce9e29cfe6fa1f6f6b65005
ToppCelldroplet-Liver-LIVER-NPC-1m-Myeloid-plasmacytoid_dendritic_cells|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC44A2 DNAJC7 MYO5A

5.66e-04168433e8878ec68b21c8d5694d7209b816d2f869673164
ToppCelldroplet-Liver-LIVER-NPC-1m-Myeloid-plasmacytoid_dendritic_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC44A2 DNAJC7 MYO5A

5.66e-04168433a007758c219d3d5db2b5529f29af63be0d408304
ToppCellnormal_Pleural_Fluid-Myeloid_cells-CD163+CD14+_DCs|Myeloid_cells / Location, Cell class and cell subclass

SLC44A2 WEE1 SYNE2

5.75e-04169433bea8aba1f3cc3d0e8d448c1c45f5354d26ebf850
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

KIF4A DMD NALCN

5.85e-04170433fa753cc8fbd04e63c9a303da4dc17ee2ce907f92
ToppCellCOVID-19-Heart-CM_+_Macrophage|COVID-19 / Disease (COVID-19 only), tissue and cell type

MYH6 DMD ANKRD1

5.85e-041704333f15242a1d3e4e9871d9170b2ef05842fb609c29
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

KIF4A DMD NALCN

5.85e-0417043303044e1436443b28dd39d5ef4fdb25c18e3a7546
ToppCell3'_v3-Lung-Lymphocytic_T_CD4/8-lo|Lung / Manually curated celltypes from each tissue

KIF4A OFD1 SYNE2

5.95e-04171433dfd4a15ab68ef5a9a1954b1b1540ae04017885a6
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8|lymph-node_spleen / Manually curated celltypes from each tissue

SMCHD1 ANKRD1 SYNE2

5.95e-041714332e9a20f8980b78325c52065a9c14ab3656267c05
ToppCellfacs-Marrow-Granulocytes-24m-Myeloid-granulocyte_monocyte_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMA16 SLC26A6 TTC21A

5.95e-04171433dca4aa921896ec935fb7acdf25a62d8eba679602
ToppCellfacs-Marrow-Granulocytes-24m-Myeloid-granulocyte_monocyte_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMA16 SLC26A6 TTC21A

5.95e-04171433add2f7d34889ec654b8c71b4b1f084736111dc88
ToppCellfacs-Heart-Unknown-3m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH6 DSP ANKRD1

6.06e-04172433bd468a7ea6ec832dcf6a816a1e0c03fa0f176dad
ToppCellfacs-Heart-Unknown-3m-Mesenchymal-atrial_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH6 DSP ANKRD1

6.06e-04172433ee8ce9e8c9a6d3ee2be113f77743958005f4b3f0
ToppCellBAL-Control-Lymphocyte-T/NK-Other_T-T/NK_proliferative-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

KIF4A WEE1 SYNE2

6.26e-04174433b43fb0fbb492c1be6e791a1c4d6c4e5956955ee4
ToppCellBAL-Control-Lymphocyte-T/NK-Other_T|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

KIF4A WEE1 SYNE2

6.26e-0417443394575a605c725de83f66a6cf7df9d7bb360ffc56
ToppCellBAL-Control-Lymphocyte-T/NK-Other_T-T/NK_proliferative|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

KIF4A WEE1 SYNE2

6.26e-0417443340c81ab36d7931e271e20d7d56fed32463c75f41
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-lymphocytic-T_lymphocytic-regulatory_T_cell|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

SMCHD1 SYNE2 NAB1

6.47e-04176433856a8c4211ea33d926b18d8959a03909562aa563
ToppCellCOVID-19-Heart-CM_3|COVID-19 / Disease (COVID-19 only), tissue and cell type

MYH6 DMD ANKRD1

6.47e-041764339df7a124ebafb0087da0cda133a394275d7bed81
ToppCelldroplet-Heart-nan-3m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH6 DMD TRIP11

6.47e-04176433749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCellCOPD-Lymphoid-T_Regulatory|World / Disease state, Lineage and Cell class

SMCHD1 SYNE2 NAB1

6.91e-0418043351a12fbad5fa7bb12e6d616a02ff9b5141e2b063
ToppCellControl-Lymphoid-T_Regulatory|World / Disease state, Lineage and Cell class

SMCHD1 SYNE2 NAB1

6.91e-0418043347036eee4c128fbb443d1fc767b4de5cced93f0e
ToppCellCOVID-19-Heart-CM_+_EC_+_Pericyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

MYH6 DMD ANKRD1

7.02e-04181433719eb532453ab7cd7893726885bc75d74a10b21e
ToppCell10x5'-Liver-Lymphocytic_T_CD4-T_CD4/CD8|Liver / Manually curated celltypes from each tissue

SMCHD1 SYNE2 ASH1L

7.02e-04181433f2315414e714ac86211546a935660c4be6e85f1b
ToppCelldroplet-Spleen-nan-18m|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRIP11 SMCHD1 ASH1L

7.13e-04182433eeb5dfa4539e9ca5220f26bc2b65717ddcf13b6c
ToppCellnormal-na-Lymphocytic_B-B_mem-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

PLEKHG1 WEE1 SMCHD1

7.13e-04182433ee36ea6cb9a5a08aeb83f2b7a249255f0b1a9870
ToppCellfacs-Heart-LA-3m-Mesenchymal-atrial_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH6 DSP ANKRD1

7.25e-04183433905e1e9be0f15be184447df04b134a6aa8279074
ToppCellfacs-Heart-LA-3m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH6 DSP ANKRD1

7.25e-0418343392eed783347a372b850de3189e72525082390014
ToppCellPCW_05-06-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

PLEKHG1 DMD DSP

7.25e-04183433c5b10571599dc26476170b54b53f09c23e6b3117
ToppCellCOVID-19-Heart-EC_3|COVID-19 / Disease (COVID-19 only), tissue and cell type

PLEKHG1 TBCD CD109

7.25e-04183433ff95382cfed592190d0636d2b750328471f82e0d
ToppCelldroplet-Spleen-nan-18m-Lymphocytic|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPL10A SMCHD1 ASH1L

7.25e-0418343328cbf909424f3be4491d49832f0aca0386560814
ToppCell343B-Lymphocytic-CD4_T-cell-Treg_cell_4|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

WEE1 NBR1 NAB1

7.25e-041834333cbe0175d05fd39bc430de1ef471ff2c5b56460e
ToppCelldroplet-Spleen-nan-18m-Lymphocytic-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPL10A SMCHD1 ASH1L

7.25e-041834333fa608aa6b119869ec3280dc388dfee57160e63a
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_B-B_cell-B_c03-CD27-AIM2|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

DMD WDR87 SMCHD1

7.48e-041854333563dd39ec58d3273f95f5bb36b9ccdc0aafb63a
ToppCellCOVID-19-Heart-CM_2|COVID-19 / Disease (COVID-19 only), tissue and cell type

MYH6 DMD ANKRD1

7.48e-04185433549eeb521c3985bff396ea0f202db21822efa51f
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DMD DSP ASH1L

7.48e-04185433eb7d3c1363d5fedc611f9c1a91ea823de251355e
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CCDC175 MYO5A ERC1

7.48e-04185433a0a629e5d2b65f670ea907bd3f5e3caf17687d8f
ToppCellBLOOD--(2)_Naive_B_cells| / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

PLEKHG1 DSP TTC21A

7.60e-041864332e55a3892459152fc4a3a7834ccbf5d71b65d29a
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-epithelial_cell_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPL10A KIF4A SYNE2

7.60e-041864334ed1b97e2552f3c4134f25665d7513498ffac16c
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-Lgr5-_amplifying_undifferentiated_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPL10A KIF4A SYNE2

7.60e-0418643315ab6666748a641226e42e6ca6eeaf186a501c95
ToppCelldroplet-Bladder-nan|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRIP11 SYNE2 ASH1L

7.72e-04187433663991a8afe652e92363b64bcbd68c14d0307f0e
ToppCellAdult-Endothelial-capillary_endothelial_cell_(Cap1)-D175|Adult / Lineage, Cell type, age group and donor

PLEKHG1 KIF4B CD109

7.72e-04187433f3548817f2fded5978137bb252cb628ac199e4f6
ToppCelldroplet-Lung-18m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l39|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DMD ANKRD1 CD109

7.72e-04187433218c9b4f28499389c43005d9626af2ac01066027
ToppCell390C-Lymphocytic-CD4_T-cell-Treg_cell_3|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

SETD1A ERC1 POLR3F

7.72e-041874331eed2c1a05e80a7c8f639437c117afe0c18dfb0c
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PLEKHG1 TBCD CD109

7.72e-0418743335c382c0aabd46906113e5db30ea24bb8e658899
ToppCelldroplet-Lung-18m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DMD ANKRD1 CD109

7.72e-04187433c7ac4b328efc2ebb72f71154661914193ff402ca
ToppCellPBMC-Mild-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-6|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PLEKHG1 DMD WEE1

7.84e-0418843318d16e3f095a109b6a690f46fe7fcd5674c3636b
ToppCellLA-03._Atrial_Cardiomyocyte|World / Chamber and Cluster_Paper

MYH6 DMD ANKRD1

7.84e-041884336d249fe92d51a19da19ec14bb2262d394255d577
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

SMCHD1 SYNE2 ASH1L

7.84e-04188433ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCellfacs-Heart-LA/RA-3m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH6 DSP ANKRD1

7.84e-0418843390dc0e15798d0b984518ad58c7e416e30aff687a
ToppCellfacs-Heart-LA/RA-3m-Mesenchymal-atrial_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH6 DSP ANKRD1

7.84e-04188433f63dfd076ced81013918363282ae25cbbd8948ae
ToppCelldroplet-Lung-nan-18m-Mesenchymal-Airway_Smooth_Muscle|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DMD ANKRD1 CD109

7.84e-0418843361f010c165826b434ca3d27553d4c9e13d2c0c51
ToppCellfacs-Heart-LA/RA-3m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH6 DSP ANKRD1

7.84e-041884330554d542149cef654ff1e5e32dfbffd8990b52bd
ToppCellnormal-na-Lymphocytic_B-B_naive-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

PLEKHG1 DSP SMCHD1

7.84e-04188433ec72ba73b10c6f2ff39699b6b46b90a3e95a4c24
ToppCellPCW_10-12-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

PLEKHG1 DMD DSP

7.84e-04188433beb2df2332a46cc81b10e8e29fc9829020111f03
ToppCelldroplet-Lung-nan-18m-Mesenchymal-bronchial_smooth_muscle_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DMD ANKRD1 CD109

7.84e-041884337553ef7de3575af4cf34704b405b551c1af8eb83
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

PLEKHG1 DMD DSP

7.96e-041894337659c7bbd58ee959a159294fb8d17317bbcc5681
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

TRIP11 SMCHD1 SYNE2 ASH1L

6.72e-0650274GAVISH_3CA_MALIGNANT_METAPROGRAM_4_CHROMATIN
Diseasedilated cardiomyopathy (is_implicated_in)

DMD DSP ANKRD1

3.18e-0543423DOID:12930 (is_implicated_in)
DiseaseFamilial dilated cardiomyopathy

MYH6 DMD ANKRD1

3.41e-0544423C0340427
DiseaseCardiomyopathies

MYH6 DMD DSP ANKRD1

3.54e-05130424C0878544
DiseaseCardiomyopathy

MYH6 DSP ANKRD1

4.16e-0547423cv:C0878544
DiseaseHypertrophic Cardiomyopathy

MYH6 DSP ANKRD1

7.44e-0557423C0007194
DiseaseMuscle Weakness

DMD TBCD

8.84e-0510422C0151786
Diseasesphingosine 1-phosphate measurement

UBE2O DMD

2.98e-0418422EFO_0800185
Diseaseretinal degeneration (biomarker_via_orthology)

DMD OFD1

7.30e-0428422DOID:8466 (biomarker_via_orthology)
DiseaseDevelopmental Disabilities

SETD1A TBCD

8.39e-0430422C0008073
DiseasePrimary dilated cardiomyopathy

MYH6 ANKRD1

1.08e-0334422cv:C0007193

Protein segments in the cluster

PeptideGeneStartEntry
KNLDHVNKILKAKKL

ASH1L

1821

Q9NR48
KKKKLEQRSKLENLE

ANKRD1

71

Q15327
LSKLLGKKKELQDLE

GSDMA

286

Q96QA5
QKLAVLKADLEKKKQ

DMD

601

P11532
KKDLKDLKEKVSLLQ

ERC1

651

Q8IUD2
KEEKLELLAQNKLLK

OFD1

441

O75665
KKLREITDKKKINLL

HPF1

171

Q9NWY4
NEVKELLKTNKKLAK

NAB1

216

Q13506
KKALLKLEKLDTDLK

GPS1

136

Q13098
KQLKNLKRKEILAKL

KRI1

351

Q8N9T8
KKKQLTDNLKEKALS

CD109

941

Q6YHK3
QKADLLLLENKKLKE

CCDC175

651

P0C221
KLDLLLEKTKELQKL

CDK5RAP3

471

Q96JB5
LKKIKNDLNLKKSLL

DSP

811

P15924
EQNSKLVDLKLKKLL

EHBP1

941

Q8NDI1
LLKNAQLELKKSKRK

DNAJC7

366

Q99615
RLKLLEKKKTELAQK

IST1

21

P53990
DLKKKLNEQSKLLKL

KIF4A

611

O95239
DLKKKLNEQSKLLKL

KIF4B

611

Q2VIQ3
TLKKLLNKTNKKAAE

SLC44A2

691

Q8IWA5
KKKLTQNKLILKGEL

PTCD2

81

Q8WV60
QDQKILSLKNKLKDL

USO1

916

O60763
LLKRKLSEQEELKKK

SMCHD1

1691

A6NHR9
LTLQKEKLQKLLKDS

SYNE2

306

Q8WXH0
KKFLKKAQDLTSLLK

SYNE2

2186

Q8WXH0
QRKAEVKELKKQLKL

NBR1

311

Q14596
LKLKQLQKEEKLRKQ

SLC26A6

586

Q9BXS9
ILKNLESKKLIKAVK

POLR3F

126

Q9H1D9
LENDKLQLEEKLKKK

MYH6

1071

P13533
DLLKLNQLKFRKKKL

SETD1A

1556

O15047
AEKFKNSLLQKELKK

WEE1

586

P30291
KKFLDDIKKLQENLK

UBE2O

851

Q9C0C9
IALKALKKALLLYKK

TEX11

791

Q8IYF3
LGKLLLKLKKVNKAE

TTC21A

801

Q8NDW8
DIEALKKLNKNKKLV

RPL10A

86

P62906
KQLKEKQDVLQKLLK

TRIP11

1396

Q15643
KQDVLQKLLKEKDLL

TRIP11

1401

Q15643
QKLLKEKDLLIKAKS

TRIP11

1406

Q15643
KKEIKNSKDIQKLLS

TBCD

1076

Q9BTW9
KIKKANQLLKVKSLE

PLEKHG1

986

Q9ULL1
KKNKKLILDFVLKQD

TIGD7

46

Q6NT04
KDLKLLLNDTINKSK

WDR87

11

Q6ZQQ6
NLNEKIKKDELKKSL

SNRPA

16

P09012
KKEKLKNEKALRLNL

TMA16

36

Q96EY4
NLELDEDLKKLKQLK

NALCN

601

Q8IZF0
KKLKNELNELRKALS

MYO5A

1216

Q9Y4I1