Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	catalytic activity, acting on a nucleic acid	IARS2 CNOT7 MYO18A MCM7 MSH3 RAD54L2 PTBP1 DUS3L AARSD1 MOV10	7.97e-05	645	70	10	GO:0140640
GeneOntologyBiologicalProcess	cerebellar granule cell precursor tangential migration	TTBK2 PLXNA2	1.04e-05	2	67	2	GO:0021935
GeneOntologyBiologicalProcess	positive regulation of establishment of protein localization	FLNA CACNB3 CCT3 ABCC8 HPS4 MYO18A ISL1 PTBP1	4.72e-05	403	67	8	GO:1904951
GeneOntologyBiologicalProcess	cell migration in hindbrain	TTBK2 FLNA PLXNA2	5.54e-05	23	67	3	GO:0021535
GeneOntologyBiologicalProcess	detection of mechanical stimulus involved in sensory perception of touch	CACNB3 KCNK4	6.21e-05	4	67	2	GO:0050976
GeneOntologyBiologicalProcess	regulation of cell projection organization	LRIG2 TTBK2 FLNA TBC1D9B MYCBP2 PROM2 FAT3 ROBO2 PTBP1 PLXNA2 MOV10	9.71e-05	863	67	11	GO:0031344
GeneOntologyBiologicalProcess	hindbrain tangential cell migration	TTBK2 PLXNA2	1.03e-04	5	67	2	GO:0021934
GeneOntologyBiologicalProcess	negative regulation of protein K63-linked ubiquitination	PARP10 PLAA	1.03e-04	5	67	2	GO:1900045
GeneOntologyBiologicalProcess	positive regulation of protein localization	LRIG2 FLNA CACNB3 CCT3 ABCC8 HPS4 MYO18A ISL1 PTBP1	1.19e-04	591	67	9	GO:1903829
GeneOntologyBiologicalProcess	sensory perception of touch	CACNB3 KCNK4	2.16e-04	7	67	2	GO:0050975
Domain	Filamin	FLNA MYCBP2	7.03e-04	11	68	2	PF00630
Domain	FILAMIN_REPEAT	FLNA MYCBP2	7.03e-04	11	68	2	PS50194
Domain	Filamin/ABP280_rpt	FLNA MYCBP2	7.03e-04	11	68	2	IPR001298
Domain	Filamin/ABP280_repeat-like	FLNA MYCBP2	7.03e-04	11	68	2	IPR017868
Domain	zf-RING_2	AMFR MYCBP2 BRAP	8.98e-04	52	68	3	PF13639
Domain	P-loop_NTPase	CACNB3 ABCC8 MYO18A MAGI3 AK4 MCM7 MSH3 RAD54L2 MOV10	3.50e-03	848	68	9	IPR027417
Domain	EGF_CA	HMCN2 FAT3 LTBP2	3.81e-03	86	68	3	PF07645
Domain	Guanylate_kin	CACNB3 MAGI3	4.01e-03	26	68	2	PF00625
Domain	GK/Ca_channel_bsu	CACNB3 MAGI3	4.01e-03	26	68	2	IPR008145
Domain	Guanylate_kin-like_dom	CACNB3 MAGI3	4.01e-03	26	68	2	IPR008144
Domain	GuKc	CACNB3 MAGI3	4.01e-03	26	68	2	SM00072
Domain	EGF_Ca-bd_CS	HMCN2 FAT3 LTBP2	5.33e-03	97	68	3	IPR018097
Domain	-	CACNB3 ABCC8 MYO18A AK4 MCM7 MSH3 RAD54L2 MOV10	5.56e-03	746	68	8	3.40.50.300
Domain	EGF_CA	HMCN2 FAT3 LTBP2	5.64e-03	99	68	3	PS01187
Domain	ASX_HYDROXYL	HMCN2 FAT3 LTBP2	5.80e-03	100	68	3	PS00010
Domain	Ig_E-set	FLNA MYCBP2 PLXNA2	6.47e-03	104	68	3	IPR014756
Domain	EGF-type_Asp/Asn_hydroxyl_site	HMCN2 FAT3 LTBP2	6.82e-03	106	68	3	IPR000152
Pubmed	Defining the membrane proteome of NK cells.	CEP350 CYB5B AMFR FLNA MYCBP2 APMAP CNOT7 MYO18A GOLIM4 MCM7 MSH3 NUP93 PTBP1 NBR1 FKBP5 GNPAT	2.06e-09	1168	73	16	19946888
Pubmed	Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.	IVL CYB5B PARP10 FLNA IARS2 PLAA CCT3 MAT2A APMAP MYO18A GOLIM4 MCM7 NUP93 AARSD1 BRAP	1.30e-07	1367	73	15	32687490
Pubmed	Human Immunodeficiency Virus Type 1 Vpr Mediates Degradation of APC1, a Scaffolding Component of the Anaphase-Promoting Complex/Cyclosome.	CEP350 ALMS1 MYCBP2 NUP93 DUS3L NBR1 MOV10	7.98e-07	242	73	7	34011540
Pubmed	A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.	HAUS8 AMFR APMAP CNOT7 GOLIM4 MCM7 MSH3 NUP93 GNPAT	2.65e-06	560	73	9	35241646
Pubmed	AIMP2-DX2 provides therapeutic interface to control KRAS-driven tumorigenesis.	FLNA CCT3 MAT2A MCM7 NUP93 PTBP1	4.14e-06	200	73	6	35546148
Pubmed	The E3 ubiquitin ligase Mycbp2 genetically interacts with Robo2 to modulate axon guidance in the mouse olfactory system.	MYCBP2 ROBO2	4.35e-06	2	73	2	23525682
Pubmed	Proteomic identification of common SCF ubiquitin ligase FBXO6-interacting glycoproteins in three kinds of cells.	LRIG2 CCT3 AMOT MAT2A APMAP MCM7 NUP93 PTBP1 ITGAV	5.51e-06	613	73	9	22268729
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	CYB5B CRACD AMFR FLNA IARS2 TBC1D9B CCT3 CNOT7 MCM7 NUP93 PTBP1 FKBP5 MOV10	8.48e-06	1440	73	13	30833792
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	NUSAP1 EPC2 FLNA CCT3 MYCBP2 MAT2A MCM7 NUP93 RAD54L2 PTBP1 FKBP5	1.83e-05	1103	73	11	34189442
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	CEP350 HAUS8 IARS2 ALMS1 MYCBP2 ICE2 NBR1 FKBP5 BRAP	2.28e-05	733	73	9	34672954
Pubmed	Protein interactome reveals converging molecular pathways among autism disorders.	FLNA TBC1D9B KIAA1549L CCT3 MYCBP2 MAGI3 SPARCL1 RAD54L2	2.31e-05	560	73	8	21653829
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	FLNA PLAA CCT3 MYCBP2 MAT2A MCM7 MSH3 NUP93 PTBP1 DUS3L AARSD1 MOV10	2.34e-05	1353	73	12	29467282
Pubmed	Slit and Semaphorin signaling governed by Islet transcription factors positions motor neuron somata within the neural tube.	ROBO2 ISL1 PLXNA2	2.50e-05	27	73	3	25843547
Pubmed	Robo1 and 2 Repellent Receptors Cooperate to Guide Facial Neuron Cell Migration and Axon Projections in the Embryonic Mouse Hindbrain.	ROBO2 ISL1	2.60e-05	4	73	2	30685539
Pubmed	Tumor suppressor BAP1 nuclear import is governed by transportin-1.	FLNA CCT3 MYCBP2 AMOT MAT2A MYO18A MCM7 NUP93 PTBP1 FKBP5 MOV10	2.66e-05	1149	73	11	35446349
Pubmed	The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.	CYB5B AMFR FLNA AMOT APMAP GOLIM4 MCM7 NUP93 PTBP1 ITGAV GNPAT	4.04e-05	1203	73	11	29180619
Pubmed	A protein-protein interaction map of the TNF-induced NF-κB signal transduction pathway.	IVL ALMS1 AMOT ROBO2 DUS3L NBR1	4.26e-05	302	73	6	30561431
Pubmed	Proximity interactions among centrosome components identify regulators of centriole duplication.	CEP350 HAUS8 ALMS1 MYCBP2	6.25e-05	101	73	4	24613305
Pubmed	∆F508 CFTR interactome remodelling promotes rescue of cystic fibrosis.	TTBK2 AMFR TBC1D9B MAT2A APMAP MYO18A MCM7 MOV10	6.38e-05	647	73	8	26618866
Pubmed	Semaphorin-Plexin signaling influences early ventral telencephalic development and thalamocortical axon guidance.	ISL1 PLXNA2	6.48e-05	6	73	2	28438183
Pubmed	PlexinA2 and Sema6A are required for retinal progenitor cell migration.	ISL1 PLXNA2	6.48e-05	6	73	2	27301906
Pubmed	Wnt5a and Wnt11 inhibit the canonical Wnt pathway and promote cardiac progenitor development via the Caspase-dependent degradation of AKT.	ISL1 PLXNA2	6.48e-05	6	73	2	25482987
Pubmed	hnRNPA1 couples nuclear export and translation of specific mRNAs downstream of FGF-2/S6K2 signalling.	IVL FLNA CCT3 PTBP1 FKBP5 MOV10	9.02e-05	346	73	6	25324306
Pubmed	SERBP1 Promotes Stress Granule Clearance by Regulating 26S Proteasome Activity and G3BP1 Ubiquitination and Protects Male Germ Cells from Thermostimuli Damage.	FLNA IARS2 PLAA CCT3 AMOT MAT2A AK4 MCM7 NUP93	9.15e-05	878	73	9	37223481
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	IVL HAUS8 GPBP1L1 MYCBP2 AMOT APMAP CNOT7 MCM7 ITGAV MOV10 CCDC144A	9.34e-05	1321	73	11	27173435
Pubmed	Cell cycle-dependent phosphorylation regulates RECQL4 pathway choice and ubiquitination in DNA double-strand break repair.	NUSAP1 HMCN2 CCT3 MAT2A ICE2 MCM7 NUP93 PTBP1 DUS3L FKBP5 MOV10	1.02e-04	1335	73	11	29229926
Pubmed	Compartmentalization of the SUMO/RNF4 pathway by SLX4 drives DNA repair.	CEP350 FLNA CCT3 MCM7 MSH3 PTBP1	1.07e-04	357	73	6	37059091
Pubmed	Mutual regulation between OGT and XIAP to control colon cancer cell growth and invasion.	NUSAP1 HAUS8 CCT3 MAT2A APMAP PTBP1 FKBP5 AARSD1	1.14e-04	704	73	8	32994395
Pubmed	Cardiac neural crest orchestrates remodeling and functional maturation of mouse semilunar valves.	ISL1 PLXNA2	1.21e-04	8	73	2	21157040
Pubmed	Motor axons are guided to exit points in the spinal cord by Slit and Netrin signals.	ROBO2 ISL1	1.21e-04	8	73	2	28986144
Pubmed	Expression, functional, and structural analysis of proteins critical for otoconia development.	DSPP SPARCL1	1.21e-04	8	73	2	20803598
Pubmed	The ATG5 interactome links clathrin-mediated vesicular trafficking with the autophagosome assembly machinery.	PLAA CCT3 MYO18A FKBP5 GNPAT	1.26e-04	230	73	5	35449600
Pubmed	DYRK1A regulates the recruitment of 53BP1 to the sites of DNA damage in part through interaction with RNF169.	ICE2 CNOT7 RAD54L2 MOV10	1.30e-04	122	73	4	30773093
Pubmed	VE-822 upregulates the deubiquitinase OTUD1 to stabilize FHL1 to inhibit the progression of lung adenocarcinoma.	FLNA CCT3 MAT2A MCM7	1.30e-04	122	73	4	36929488
Pubmed	Host E3 ligase HUWE1 attenuates the proapoptotic activity of the MERS-CoV accessory protein ORF3 by promoting its ubiquitin-dependent degradation.	AMFR FLNA AMOT AK4 MCM7 NUP93 PTBP1	1.31e-04	534	73	7	35032548
Pubmed	A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.	CEP350 HAUS8 FLNA MYCBP2 AMOT ICE2 MYO18A MOV10	1.39e-04	724	73	8	36232890
Pubmed	Prohibitin 1 regulates tumor cell apoptosis via the interaction with X-linked inhibitor of apoptosis protein.	NUSAP1 FLNA PLAA CCT3 MAT2A MCM7 NUP93 PTBP1	1.40e-04	725	73	8	27025967
Pubmed	The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation.	NUSAP1 FLNA CCT3 DSPP AMOT MAT2A PTBP1 DUS3L FKBP5 MOV10	1.44e-04	1153	73	10	29845934
Pubmed	PLK4 deubiquitination by Spata2-CYLD suppresses NEK7-mediated NLRP3 inflammasome activation at the centrosome.	FLNA ALMS1 AMOT	1.52e-04	49	73	3	31762063
Pubmed	Retinal ganglion cell axon guidance in the mouse optic chiasm: expression and function of robos and slits.	ROBO2 ISL1	1.55e-04	9	73	2	10864955
Pubmed	Spinocerebellar ataxia type 11-associated alleles of Ttbk2 dominantly interfere with ciliogenesis and cilium stability.	TTBK2 ISL1	1.55e-04	9	73	2	30532139
Pubmed	A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1.	NBR1 AARSD1	1.55e-04	9	73	2	7545954
Pubmed	Casz1 is required for cardiomyocyte G1-to-S phase progression during mammalian cardiac development.	FLNA ISL1	1.55e-04	9	73	2	25953344
Pubmed	Defective glucocorticoid receptor signaling and keratinocyte-autonomous defects contribute to skin phenotype of mouse embryos lacking the Hsp90 co-chaperone p23.	IVL FKBP5	1.55e-04	9	73	2	28650975
Pubmed	FGF11 induced by hypoxia interacts with HIF-1α and enhances its stability.	CCT3 MAT2A PTBP1 MOV10	1.57e-04	128	73	4	28027390
Pubmed	A regulatory circuit that involves HR23B and HDAC6 governs the biological response to HDAC inhibitors.	PLAA CCT3 MCM7	1.62e-04	50	73	3	23703321
Pubmed	TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.	NUSAP1 FLNA CCT3 MAT2A MYO18A MCM7 NUP93 PTBP1 MOV10	1.64e-04	949	73	9	36574265
Pubmed	Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.	ALMS1 MCF2L2 MAGI3 PLXNA2	1.66e-04	130	73	4	12421765
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	FLNA IARS2 CCT3 AMOT MAT2A APMAP MCM7 MSH3 NUP93 PTBP1 NBR1	1.81e-04	1425	73	11	30948266
Pubmed	Plexin A3 and plexin A4 convey semaphorin signals during facial nerve development.	ISL1 PLXNA2	1.93e-04	10	73	2	18804103
Pubmed	The secondary heart field is a new site of calcineurin/Nfatc1 signaling for semilunar valve development.	ISL1 PLXNA2	1.93e-04	10	73	2	22300732
Pubmed	The spinocerebellar ataxia-associated gene Tau tubulin kinase 2 controls the initiation of ciliogenesis.	TTBK2 ISL1	1.93e-04	10	73	2	23141541
Pubmed	Beta-catenin directly regulates Islet1 expression in cardiovascular progenitors and is required for multiple aspects of cardiogenesis.	ISL1 PLXNA2	1.93e-04	10	73	2	17519333
Pubmed	Slit/Robo signals prevent spinal motor neuron emigration by organizing the spinal cord basement membrane.	ROBO2 ISL1	1.93e-04	10	73	2	31356769
Pubmed	Isl1 is upstream of sonic hedgehog in a pathway required for cardiac morphogenesis.	ISL1 PLXNA2	1.93e-04	10	73	2	16687132
Pubmed	In silico APC/C substrate discovery reveals cell cycle-dependent degradation of UHRF1 and other chromatin regulators.	NUSAP1 FLNA PLAA CCT3 MAT2A MCM7 PTBP1 FKBP5 MOV10	1.95e-04	971	73	9	33306668
Pubmed	Multi-omics profiling identifies a deregulated FUS-MAP1B axis in ALS/FTD-associated UBQLN2 mutants.	FLNA CCT3 MAT2A MCM7 NUP93	2.08e-04	256	73	5	35777956
Pubmed	Nuclear import of histone deacetylase 5 by requisite nuclear localization signal phosphorylation.	FLNA CCT3 MCM7 NUP93 PTBP1	2.15e-04	258	73	5	21081666
Pubmed	LINC01554-Mediated Glucose Metabolism Reprogramming Suppresses Tumorigenicity in Hepatocellular Carcinoma via Downregulating PKM2 Expression and Inhibiting Akt/mTOR Signaling Pathway.	CCT3 MYO18A MCM7 PTBP1	2.33e-04	142	73	4	30809309
Pubmed	Murine Jagged1/Notch signaling in the second heart field orchestrates Fgf8 expression and tissue-tissue interactions during outflow tract development.	ISL1 PLXNA2	2.36e-04	11	73	2	19509466
Pubmed	An Immunocompetent Mouse Model of HPV16(+) Head and Neck Squamous Cell Carcinoma.	IVL MCM7	2.36e-04	11	73	2	31693903
Pubmed	Motor axon exit from the mammalian spinal cord is controlled by the homeodomain protein Nkx2.9 via Robo-Slit signaling.	ROBO2 ISL1	2.36e-04	11	73	2	22399681
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	FLNA ALMS1 MYCBP2 AMOT ZKSCAN3 MCM7	2.51e-04	418	73	6	34709266
Pubmed	Association studies of variants in the genes involved in pancreatic beta-cell function in type 2 diabetes in Japanese subjects.	ABCC8 ISL1	2.83e-04	12	73	2	16873704
Pubmed	Robo2 is required for Slit-mediated intraretinal axon guidance.	ROBO2 ISL1	2.83e-04	12	73	2	19782674
Pubmed	The CEP19-RABL2 GTPase Complex Binds IFT-B to Initiate Intraflagellar Transport at the Ciliary Base.	CEP350 TTBK2	2.83e-04	12	73	2	28625565
Pubmed	mTORC1 activity regulates post-translational modifications of glycine decarboxylase to modulate glycine metabolism and tumorigenesis.	FLNA AMOT MYO18A PTBP1 MOV10	2.84e-04	274	73	5	34244482
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	CEP350 FLNA CCT3 MYCBP2 AMOT APMAP MCM7 NUP93 PTBP1	2.88e-04	1024	73	9	24711643
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	NUSAP1 FLNA IARS2 CCT3 MAT2A MYO18A MCM7 NUP93 PTBP1 MOV10	2.88e-04	1257	73	10	36526897
Pubmed	A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.	CEP350 KIAA1549L MYO18A ROBO2 RAD54L2 PTBP1 NBR1	2.90e-04	608	73	7	16713569
Pubmed	Wnt regulation: exploring Axin-Disheveled interactions and defining mechanisms by which the SCF E3 ubiquitin ligase is recruited to the destruction complex.	FLNA IARS2 CCT3 MYCBP2 AMOT MAT2A GOLIM4 PTBP1	2.93e-04	809	73	8	32129710
Pubmed	Network organization of the human autophagy system.	FLNA CCT3 AMOT NUP93 NBR1 FKBP5	3.18e-04	437	73	6	20562859
Pubmed	PARK2 promotes mitochondrial pathway of apoptosis and antimicrotubule drugs chemosensitivity via degradation of phospho-BCL-2.	CCT3 MAT2A MCM7 NUP93 PTBP1	3.68e-04	290	73	5	32929329
Pubmed	A protein interaction landscape of breast cancer.	CYB5B IARS2 PLAA MYO18A GOLIM4 MSH3 FKBP5	3.72e-04	634	73	7	34591612
Pubmed	ARHGAP24 represses β-catenin transactivation-induced invasiveness in hepatocellular carcinoma mainly by acting as a GTPase-independent scaffold.	CCT3 AMOT MAT2A MCM7 NUP93 MOV10	3.76e-04	451	73	6	36168627
Pubmed	Motor neuron cell bodies are actively positioned by Slit/Robo repulsion and Netrin/DCC attraction.	ROBO2 ISL1	3.89e-04	14	73	2	25530182
Pubmed	The role of Sema3-Npn-1 signaling during diaphragm innervation and muscle development.	ROBO2 ISL1	3.89e-04	14	73	2	27466379
Pubmed	Expression of the BMP receptor Alk3 in the second heart field is essential for development of the dorsal mesenchymal protrusion and atrioventricular septation.	FLNA ISL1	3.89e-04	14	73	2	23584254
Pubmed	Suppression of ACE2 SUMOylation protects against SARS-CoV-2 infection through TOLLIP-mediated selective autophagy.	PLAA CCT3 AMOT MAT2A MCM7 NUP93 PTBP1	3.98e-04	641	73	7	36057605
Pubmed	Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.	CEP350 NUSAP1 EPC2 HAUS8 ALMS1 MYCBP2 AMOT	4.13e-04	645	73	7	25281560
Pubmed	The p300/YY1/miR-500a-5p/HDAC2 signalling axis regulates cell proliferation in human colorectal cancer.	NUSAP1 FLNA GPBP1L1 CCT3 MCM7	4.17e-04	298	73	5	30737378
Pubmed	Rewiring of the Human Mitochondrial Interactome during Neuronal Reprogramming Reveals Regulators of the Respirasome and Neurogenesis.	CYB5B IARS2 CCT3 AK4 LTBP2 NUP93 ITGAV GNPAT	4.37e-04	859	73	8	31536960
Pubmed	Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.	HAUS8 ALMS1 CCT3 MCM7 NUP93 MOV10	4.62e-04	469	73	6	27634302
Pubmed	PINK1 Content in Mitochondria is Regulated by ER-Associated Degradation.	AMFR FLNA IARS2 CCT3 NUP93 MOV10	5.05e-04	477	73	6	31300519
Pubmed	The Amot/Patj/Syx signaling complex spatially controls RhoA GTPase activity in migrating endothelial cells.	FLNA AMOT	5.12e-04	16	73	2	18824598
Pubmed	A Tbx1-Six1/Eya1-Fgf8 genetic pathway controls mammalian cardiovascular and craniofacial morphogenesis.	ISL1 PLXNA2	5.12e-04	16	73	2	21364285
Pubmed	DNA damage shifts circadian clock time via Hausp-dependent Cry1 stabilization.	FLNA MYCBP2 MCM7 PTBP1	5.14e-04	175	73	4	25756610
Pubmed	Charting the landscape of tandem BRCT domain-mediated protein interactions.	CEP350 AMFR FLNA ALMS1 NUP93 MOV10 GNPAT	5.17e-04	670	73	7	22990118
Pubmed	The ubiquitin-specific protease USP36 SUMOylates EXOSC10 and promotes the nucleolar RNA exosome function in rRNA processing.	CEP350 NUSAP1 FLNA CCT3 MAT2A MCM7	5.40e-04	483	73	6	36912080
Pubmed	A human MAP kinase interactome.	CEP350 FLNA KIAA1549L CCT3 HPS4 MYO18A	5.57e-04	486	73	6	20936779
Pubmed	A critical role for the chromatin remodeller CHD7 in anterior mesoderm during cardiovascular development.	ROBO2 ISL1	5.79e-04	17	73	2	26102480
Pubmed	Fbxo45 forms a novel ubiquitin ligase complex and is required for neuronal development.	MYCBP2 ISL1	5.79e-04	17	73	2	19398581
Pubmed	Slit2 activity in the migration of guidepost neurons shapes thalamic projections during development and evolution.	ROBO2 ISL1	5.79e-04	17	73	2	21435555
Pubmed	Proximity labeling reveals dynamic changes in the SQSTM1 protein network.	GPBP1L1 PLAA ALMS1 AMOT NBR1	5.92e-04	322	73	5	39098523
Pubmed	Quantitative interaction proteomics of neurodegenerative disease proteins.	TBC1D9B CCT3 MAT2A CNOT7 MOV10	6.00e-04	323	73	5	25959826
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	CEP350 LRIG2 TBC1D9B ALMS1 MAGI3 MOV10	6.01e-04	493	73	6	15368895
Pubmed	FBXW7 modulates cellular stress response and metastatic potential through HSF1 post-translational modification.	CCT3 MYCBP2 FKBP5	6.03e-04	78	73	3	25720964
Pubmed	CHK2-BRCA1 tumor-suppressor axis restrains oncogenic Aurora-A kinase to ensure proper mitotic microtubule assembly.	FLNA ALMS1 CCT3 NUP93 PTBP1 MOV10	6.07e-04	494	73	6	26831064
Pubmed	Cracking the egg: molecular dynamics and evolutionary aspects of the transition from the fully grown oocyte to embryo.	HAUS8 PLAA ALMS1 CNOT7 DUS3L	6.26e-04	326	73	5	17015433
Pubmed	Forkhead transcription factors, Foxc1 and Foxc2, are required for the morphogenesis of the cardiac outflow tract.	ISL1 PLXNA2	6.51e-04	18	73	2	16839542
Interaction	ASB8 interactions	IARS2 MYCBP2 MCM7 MOV10	4.72e-06	32	71	4	int:ASB8
ToppCell	TCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_NOS\|TCGA-Stomach / Sample_Type by Project: Shred V9	NUSAP1 CYB5B CCT3 APMAP MCM7 NUP93 BRAP	3.32e-08	198	72	7	08f9f05abad4e4078362ea8537c616084cb5d70a
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM2_(12)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	FLNA FIBCD1 ROBO2 LTBP2 PLXNA2	1.35e-05	188	72	5	3004e961d214919e08c7cd5f10c3de5cf85b35a3
ToppCell	droplet-Trachea-3m-Epithelial-airway_epithelial-neuroendocrine_cell-neuroendocrine\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FLNA XIRP1 ADAMTS20 SPARCL1 QRICH2	1.45e-05	191	72	5	72f1ddc09080dbfea8d51294cbf7f9d4925f9cc0
ToppCell	droplet-Trachea-3m-Epithelial-airway_epithelial-neuroendocrine_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FLNA XIRP1 ADAMTS20 SPARCL1 QRICH2	1.45e-05	191	72	5	6e7f589efc997f32175e0789c5ea7ca46e1389b8
ToppCell	droplet-Trachea-nan-3m-Epithelial-neuroendocrine_cell\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLNA XIRP1 ADAMTS20 SPARCL1 QRICH2	1.45e-05	191	72	5	3ce403e0beedb544edeb3ae6eb30267040d00c21
ToppCell	wk_08-11-Mesenchymal-Myofibro_&_SMC-Early_airway_SMC_1\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	FLNA FIBCD1 ROBO2 SPARCL1 LTBP2	1.49e-05	192	72	5	7ae3e1ca8bfc078c0e12a1595ecb0e343dab5d2f
ToppCell	Control-Stromal-Myofibroblast\|Stromal / Disease state, Lineage and Cell class	FLNA FAT3 ROBO2 SPARCL1 PLXNA2	1.53e-05	193	72	5	5896242f713ae5fd1a4ebb63827f15d7279dced2
ToppCell	E17.5-Mesenchymal-myocytic_cell-aortic_smooth_muscle_cell\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	CACNB3 ROBO2 LTBP2 FKBP5 PLXNA2	1.61e-05	195	72	5	1daddd801bd4596fffbdb822fc326d5127c96004
ToppCell	metastatic_Lymph_Node-B_lymphocytes-GC_B_cells_in_the_DZ\|metastatic_Lymph_Node / Location, Cell class and cell subclass	NUSAP1 HAUS8 C21orf58 MCM7 CCDC144A	1.61e-05	195	72	5	3c5b7cce4a1c4b28fa3b657cce4148669a59e55e
ToppCell	Bronchial-NucSeq-Stromal-Fibroblastic-Fibro_myofibroblast\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PARP10 CRACD FAT3 ROBO2 LTBP2	1.61e-05	195	72	5	f5e91ce20a7ce528dc4c1a968c7bf096bf45c528
ToppCell	11.5-Distal-Mesenchymal-Airway_Smooth_Muscle\|Distal / Age, Tissue, Lineage and Cell class	FLNA FIBCD1 ROBO2 LTBP2 PLXNA2	1.65e-05	196	72	5	05530fe7a5681c2f39b95016cd22ef99d6ac0430
ToppCell	E16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FLNA CACNB3 ROBO2 SPARCL1 LTBP2	1.73e-05	198	72	5	63f7d25201613bd3404c28fb936954190bca91d3
ToppCell	E16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FLNA CACNB3 ROBO2 SPARCL1 LTBP2	1.73e-05	198	72	5	a73534b6ca202c277a70a52281d5b97a3e6cb8ef
ToppCell	Tracheal-10x5prime-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	FLNA XIRP1 FAT3 SPARCL1 FKBP5	1.73e-05	198	72	5	1e1ea54f0c234f3b6d29064c4881d8a0c0949a75
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW13-Stem_cells\|GW13 / Sample Type, Dataset, Time_group, and Cell type.	NUSAP1 C21orf58 GOLIM4 MCM7 PTBP1	1.77e-05	199	72	5	fd1d1b95e01719e3d0a17d9d1f29717a47209d32
ToppCell	11.5-Airway-Mesenchymal-Airway_Smooth_Muscle\|Airway / Age, Tissue, Lineage and Cell class	FLNA FIBCD1 ROBO2 SPARCL1 LTBP2	1.77e-05	199	72	5	1a8c77d241bd817a195e1532fd25f51358cb1ff1
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW13-Stem_cells-Stem_cells\|GW13 / Sample Type, Dataset, Time_group, and Cell type.	NUSAP1 C21orf58 GOLIM4 MCM7 PTBP1	1.77e-05	199	72	5	91882af9dc7265c9b419f4415cbcf656087a2ab3
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW13-Stem_cells\|GW13 / Sample Type, Dataset, Time_group, and Cell type.	NUSAP1 C21orf58 GOLIM4 MCM7 PTBP1	1.81e-05	200	72	5	d933978b55fefe52cad599b36f6b47a0c7f71f96
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW13-Stem_cells-Neuroepithelial_cell\|GW13 / Sample Type, Dataset, Time_group, and Cell type.	NUSAP1 C21orf58 GOLIM4 MCM7 PTBP1	1.81e-05	200	72	5	3d932765c31aef1f80a118d51e8e66c50a758dbb
ToppCell	COVID-19_Moderate-B_cell\|World / disease group, cell group and cell class	MAGI3 LTBP2 AARSD1 MOV10	7.63e-05	139	72	4	b93e1da87d44e55d75e8cc1b87c2970645679c01
ToppCell	COVID-19_Moderate-B_cell\|COVID-19_Moderate / disease group, cell group and cell class	MAGI3 LTBP2 AARSD1 MOV10	8.28e-05	142	72	4	88bb8d9bca66131df4ee7021b88248e146aa7aa6
ToppCell	3'_v3-lymph-node_spleen-Lymphocytic_B-GC_B_(II)\|lymph-node_spleen / Manually curated celltypes from each tissue	CRACD MYO18A QRICH2 CCDC144A	1.08e-04	152	72	4	4f690aed23338687bdefc47e8a2f3d1fdb2b6447
ToppCell	E16.5-samps-Mesenchymal-Myofibroblast-Migrating_MyoFibroblast\|E16.5-samps / Age Group, Lineage, Cell class and subclass	CACNB3 ROBO2 LTBP2 PLXNA2	1.16e-04	155	72	4	1882fa5fd25f77d6e3ac47b613f6fb3c67d8e50c
ToppCell	wk_15-18-Mesenchymal-Myofibro_&_SMC-Myofibro_2\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	FLNA FAT3 ROBO2 LTBP2	1.22e-04	157	72	4	b9d04ee417c0d8ea0801d10f1c54e138587009fd
ToppCell	Adult-Mesenchymal-myofibroblast_cell-D122\|Adult / Lineage, Cell type, age group and donor	CRACD ZSCAN32 ROBO2 LTBP2	1.25e-04	158	72	4	410fa08c9d880d27e80ec939fa5ba5a41dcb31ab
ToppCell	Children_(3_yrs)-Mesenchymal-chondrocyte-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FAT3 FIBCD1 ROBO2 LTBP2	1.25e-04	158	72	4	e5636c0b608d68bd426a2b446ac508e4512e86a4
ToppCell	Adult-Mesenchymal-chondrocyte\|Adult / Lineage, Cell type, age group and donor	FIBCD1 ROBO2 SPARCL1 LTBP2	1.28e-04	159	72	4	3f7305ee76447064b5c846c4f576360a2f7e0b7c
ToppCell	RV-13._Vascular_Smooth_Muscle\|RV / Chamber and Cluster_Paper	FLNA HMCN2 FAT3 SPARCL1	1.34e-04	161	72	4	47b3b7662cbb671ccc086dc0a0cabd65f63eb5a1
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma\|TCGA-Brain / Sample_Type by Project: Shred V9	LRIG2 GPBP1L1 ZNF436-AS1 AMOT	1.38e-04	162	72	4	810881210e015c788814e4fe8d7a24c929cf2621
ToppCell	ICU-NoSEP-Lymphocyte-T_NK-MAIT\|ICU-NoSEP / Disease, Lineage and Cell Type	AMFR AMOT ZKSCAN3 ANKRD16	1.51e-04	166	72	4	d3fa2e42497201f1ca57f4f977fbaa0def950033
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CRACD GOLIM4 ROBO2 ITGAV	1.58e-04	168	72	4	fc80e4fecfc92458eb627013a983041d8ca025a9
ToppCell	367C-Fibroblasts-Fibroblast-G\|367C / Donor, Lineage, Cell class and subclass (all cells)	FIBCD1 ROBO2 SPARCL1 LTBP2	1.58e-04	168	72	4	8c95093b1ea45826f62893edd3c410fe53b563a4
ToppCell	TCGA-Bile_Duct-Primary_Tumor-Cholangiocarcinoma-Intrahepatic-2\|TCGA-Bile_Duct / Sample_Type by Project: Shred V9	TTBK2 ALMS1 LTBP2 ITGAV	1.58e-04	168	72	4	c70bf73bb800e4722cedc35bbc17ea3113d1012d
ToppCell	367C-Fibroblasts-Fibroblast-G-\|367C / Donor, Lineage, Cell class and subclass (all cells)	FIBCD1 ROBO2 SPARCL1 LTBP2	1.58e-04	168	72	4	b8c65542a0701ae31f49d332d87a64578e24b4e3
ToppCell	390C-Lymphocytic-NK_cells-Proliferating_NK_cell\|390C / Donor, Lineage, Cell class and subclass (all cells)	NUSAP1 HMCN2 C21orf58 MCM7	1.66e-04	170	72	4	5319f73cff64f2bb67472c7156ee1d0f006c6fc0
ToppCell	PND14-Immune-Immune_Myeloid-DC-cDC1-cDC1_prolif\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	HAUS8 HPS4 MCM7 FKBP5	1.81e-04	174	72	4	09b091e24317c3f7bac043f04762a533e30793de
ToppCell	367C-Epithelial_cells-Epithelial-I_(AT1)-\|367C / Donor, Lineage, Cell class and subclass (all cells)	PROM2 MYO18A CBLC MAGI3	1.81e-04	174	72	4	edf839d79ac58921f4e788f3b2cb2ae0d6af4b9e
ToppCell	367C-Epithelial_cells-Epithelial-I_(AT1)\|367C / Donor, Lineage, Cell class and subclass (all cells)	PROM2 MYO18A CBLC MAGI3	1.81e-04	174	72	4	65539f69100db0b7d90b1b39ee15ab8281f86461
ToppCell	E16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KIAA1549L ROBO2 LTBP2 AARSD1	1.85e-04	175	72	4	1d8aab491dcc27ea5dbfb6462d18ee280b21a05e
ToppCell	E16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KIAA1549L ROBO2 LTBP2 AARSD1	1.85e-04	175	72	4	427a7ee92fe16a90625946492062d37aa0f7235b
ToppCell	pdx-Tumor_cells-T2\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	GPBP1L1 ROBO2 NBR1 GNPAT	1.89e-04	176	72	4	1e21f80cf0e695ffdd63e4a72cf1e3fa41b60341
ToppCell	droplet-Lung-LUNG-30m-Epithelial\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IVL C21orf58 PROM2 CBLC	1.89e-04	176	72	4	5201f003192c033655ba47f0faf8c47a96eae03d
ToppCell	390C-Lymphocytic-NK_cells-Proliferating_NK_cell\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	NUSAP1 HMCN2 C21orf58 MCM7	1.89e-04	176	72	4	8813c01ea080f373fe3970c5e1ba4c2dca0f7f02
ToppCell	PND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_prolif\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GOLIM4 ROBO2 MCM7 LTBP2	2.02e-04	179	72	4	ff678e2f33c914e3dd0f338ada25f506c3e3c980
ToppCell	390C-Lymphocytic-NK_cells-Proliferating_NK_cell\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	NUSAP1 HMCN2 C21orf58 MAGI3	2.02e-04	179	72	4	e67ad7ab04d0c1309296f57c1f53c5ca14c213fe
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_B-B_plasma-male\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	MYO18A MAGI3 QRICH2 CCDC144A	2.06e-04	180	72	4	8e96f8646c002768b272359af485dc0ab57e0ccd
ToppCell	Fetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	FLNA ROBO2 SPARCL1 LTBP2	2.11e-04	181	72	4	25915e2500430a902db37d79a749ce2990b69810
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Neuronal-medium_spiny_neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIAA1549L SLC24A4 ROBO2 ISL1	2.15e-04	182	72	4	d41ff834b8fc1d0e23cac7ae261de5f72874e462
ToppCell	5'-Airway_Nasal-Epithelial-Airway_epithelium-brush_cell_of_trachebronchial_tree-Tuft\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NUSAP1 CRACD CBLC ROBO2	2.15e-04	182	72	4	d1c3cc2942faec7527a3c25869fd65c17899e5e4
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Neuronal-SPN_Neuron_STR\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIAA1549L SLC24A4 ROBO2 ISL1	2.15e-04	182	72	4	6cde859edfe7607bd7ada89d20258413d06f4207
ToppCell	5'-Airway_Nasal-Epithelial-Airway_epithelium-brush_cell_of_trachebronchial_tree\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NUSAP1 CRACD CBLC ROBO2	2.15e-04	182	72	4	92f83f29e358000cd86a709eb8b6199761ffe8bd
ToppCell	5'-Airway_Nasal-Epithelial-Airway_epithelium-brush_cell_of_trachebronchial_tree-Tuft-Tuft_L.0.7.1.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NUSAP1 CRACD CBLC ROBO2	2.15e-04	182	72	4	02baca9a72c7b559c3e452693b3b134af804c868
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	IVL NUSAP1 CBLC AK4	2.15e-04	182	72	4	007fa56ed8b91f9af0df2114c00410b2f6cec8b6
ToppCell	RA-13._Vascular_Smooth_Muscle\|RA / Chamber and Cluster_Paper	FLNA HMCN2 FAT3 SPARCL1	2.20e-04	183	72	4	818fd886e0188091310825f9145fa53328f2c979
ToppCell	RA-13._Vascular_Smooth_Muscle\|World / Chamber and Cluster_Paper	FLNA HMCN2 FAT3 SPARCL1	2.20e-04	183	72	4	cae2ee08f985a6f005b4b8e959e465350315156a
ToppCell	droplet-Limb_Muscle-Pre-Sort-18m-Macroglial-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CRACD KIAA1549L CHDH CBLC	2.29e-04	185	72	4	11c147f3f5570c4761d2bcff3bad28146b4a5861
ToppCell	wk_15-18-Epithelial-Distal_epithelial_progenitor-epi-tip_intermediate\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	ZSCAN32 QRICH2 PLXNA2 CCDC144A	2.29e-04	185	72	4	636505a3d96f75d951ab42bcf8af6ae07abc732d
ToppCell	facs-Heart-LA-24m-Mesenchymal-ventricular_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CRACD XIRP1 C21orf58 ABCC8	2.34e-04	186	72	4	337f768cc43db2db96ba6495b076006b1a5b0331
ToppCell	facs-Heart-LA-24m-Mesenchymal-ventricular_myocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CRACD XIRP1 C21orf58 ABCC8	2.34e-04	186	72	4	e378c82ef6d6cb24751515aa499a01372b3e7ccf
ToppCell	5'-GW_trimst-2-SmallIntestine-Neuronal-neuron_precursor-cycling_neuroblast\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NUSAP1 KIAA1549L PROM2 MCM7	2.34e-04	186	72	4	4fe8e0bf74c7dbf73634cafdacad89020d2634d0
ToppCell	356C-Endothelial_cells-Endothelial-E-\|356C / Donor, Lineage, Cell class and subclass (all cells)	HMCN2 HHIPL2 SPARCL1 QRICH2	2.34e-04	186	72	4	2e024097ee361eeb1d855a4edb8ac8cdad35da06
ToppCell	356C-Endothelial_cells-Endothelial-E\|356C / Donor, Lineage, Cell class and subclass (all cells)	HMCN2 HHIPL2 SPARCL1 QRICH2	2.34e-04	186	72	4	c3449e54454009973818fc1101933c6f0168258c
ToppCell	E16.5-samps-Mesenchymal-Myofibroblast\|E16.5-samps / Age Group, Lineage, Cell class and subclass	ROBO2 SPARCL1 LTBP2 PLXNA2	2.34e-04	186	72	4	e044b3428b7eacfdc72d0f57cdabaa1de04c74cd
ToppCell	TCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1\|TCGA-Pancreas / Sample_Type by Project: Shred V9	CEP350 CRACD ALMS1 GOLIM4	2.34e-04	186	72	4	03db813598b67b1e08f759758a1c2023396921fa
ToppCell	LA-01._Fibroblast_I\|World / Chamber and Cluster_Paper	HMCN2 SPARCL1 LTBP2 FKBP5	2.38e-04	187	72	4	4ea486991f66c29728d127171a07b81404ec0b78
ToppCell	Control-Fibroblasts-Alveolar_FB\|Control / group, cell type (main and fine annotations)	FAT3 ROBO2 SPARCL1 LTBP2	2.38e-04	187	72	4	92d468dde81125d51daf7abd4703741abe1ab91c
ToppCell	Control-Fibroblasts-Other_FB\|Control / group, cell type (main and fine annotations)	CRACD FAT3 ROBO2 LTBP2	2.38e-04	187	72	4	bd3739c4a52aa1ba5deffd778e113a9800f7e158
ToppCell	3'-GW_trimst-2-SmallIntestine-Mesenchymal-Pericytes-angiogenic_pericyte\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HMCN2 ABCC8 LTBP2 KCNK4	2.43e-04	188	72	4	0a5b93c131ce8514e996b0c2f39e0fc98636c122
ToppCell	10x5'-Liver-Lymphocytic_NK-Cycling_NK\|Liver / Manually curated celltypes from each tissue	NUSAP1 XIRP1 C21orf58 MCM7	2.43e-04	188	72	4	5eb94e652a734c6f15c68a178e9d05f0febcf34c
ToppCell	10x_3'_v2v3-Neoplastic-Stem-like-NPC-like-NPC-like_neural-C\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	PROM2 FIBCD1 ROBO2 AARSD1	2.43e-04	188	72	4	e239bcdbd210a398a5850cb6fbf171d402f45a4f
ToppCell	Fetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	FLNA HMCN2 SPARCL1 LTBP2	2.43e-04	188	72	4	c29aaae3c5bb7cd6b9b3defd4d27afde3af19ba0
ToppCell	facs-Heart-RA-24m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CRACD XIRP1 C21orf58 ABCC8	2.48e-04	189	72	4	e4efbb0733b382f4c855f6653dcddf36e0f8df28
ToppCell	facs-Heart-RA-24m-Mesenchymal-ventricular_myocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CRACD XIRP1 C21orf58 ABCC8	2.48e-04	189	72	4	e758b264c0a47127e33e66c395cf5a3224c7305b
ToppCell	(1)_Osterolineage_cells-(10)_OLC-1\|World / Cell class and subclass of bone marrow stroma cells in homeostatis	CACNB3 FAT3 ROBO2 PLXNA2	2.48e-04	189	72	4	46c5b975fb9d33017f2d9b7770d45a8bdf95baa2
ToppCell	facs-Heart-RA-24m-Mesenchymal-ventricular_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CRACD XIRP1 C21orf58 ABCC8	2.48e-04	189	72	4	b98f60875b1a12b2ec9dc91889298ae57f98602f
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM2_(12)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	FLNA FIBCD1 LTBP2 PLXNA2	2.48e-04	189	72	4	0abc7a4900cc9033bc1be69b770ccc54a6bf41b4
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FLNA HMCN2 ABCC8 LTBP2	2.53e-04	190	72	4	2e88e366d377d74deb53a4ea870973ce5c6532e8
ToppCell	wk_15-18-Mesenchymal-Myofibro_&_SMC-Myofibro_1\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	FAT3 ROBO2 SPARCL1 LTBP2	2.53e-04	190	72	4	d24af6af3271e34afab744352afd28be8a7cc5c3
ToppCell	droplet-Tongue-nan-3m-Epithelial-filiform\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FIBCD1 ROBO2 ISL1 PLXNA2	2.53e-04	190	72	4	251e3a33041023bfc4b547c7eb68cfb8f421636f
ToppCell	Mesenchymal-airway_smooth_muscle_cell\|World / Lineage, Cell type, age group and donor	FLNA ROBO2 SPARCL1 LTBP2	2.53e-04	190	72	4	645e56b02edc3702c7db917b8ecd5eed0decaf71
ToppCell	PND07-28-samps-Mesenchymal-Matrix_fibroblast-FB-3\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	FAT3 CHDH ROBO2 SPARCL1	2.53e-04	190	72	4	1196b8ea2c44c7c80f5ee589dd517e6a413f2077
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FLNA HMCN2 ABCC8 LTBP2	2.53e-04	190	72	4	0028f886c789ba238c031eae5d96acaed4af8c25
ToppCell	NS-moderate-d_16-33-Epithelial-FOXN4+\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	ALMS1 C21orf58 FIBCD1 MCM7	2.53e-04	190	72	4	250ca4a605c1cccd77d23383e4fe6f91cf3609ba
ToppCell	PND10\|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FLNA MYCBP2 ROBO2 LTBP2	2.53e-04	190	72	4	d67e2814047c8df2ae4b7bc8be9539f5df6ecef2
ToppCell	Control-Fibroblasts\|Control / group, cell type (main and fine annotations)	FAT3 ROBO2 SPARCL1 LTBP2	2.53e-04	190	72	4	3a42a9b98d954685d38a741f44545898d0e3e9ce
ToppCell	droplet-Tongue-TONGUE-1m-Epithelial-filiform\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FIBCD1 ROBO2 ISL1 PLXNA2	2.53e-04	190	72	4	8a53f4d3c9aca45b5826f53f7dcdfb8bc8280acb
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_proliferating_SM_(20)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	NUSAP1 C21orf58 FAT3 PLXNA2	2.53e-04	190	72	4	e83fa8b711aa79a1767818474f1c193b674b1c31
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c06-TNF\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	NUSAP1 FLNA APMAP GOLIM4	2.58e-04	191	72	4	04faa7d2237e45418611153294eb6f7bb690cbde
ToppCell	facs-Pancreas-Endocrine-3m\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCC8 GOLIM4 ROBO2 ISL1	2.58e-04	191	72	4	b3de0393d6510543533cd851e47a0f95739a0e4e
ToppCell	3'-GW_trimst-2-LargeIntestine-Mesenchymal-immature_mesenchymal_cell-cycling_stromal\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NUSAP1 KIAA1549L C21orf58 MCM7	2.58e-04	191	72	4	50854384fdaa0efa2e3227659d544ed09ac102f2
ToppCell	facs-Pancreas-Endocrine-3m-Epithelial\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCC8 GOLIM4 ROBO2 ISL1	2.58e-04	191	72	4	657297cd19d05a7e7bb74fc3a086fbd95f47aae4
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	FAT3 ROBO2 SPARCL1 LTBP2	2.58e-04	191	72	4	6688cee34beee4f151ac17fccbc9c26a9aad72e1
ToppCell	PND07\|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FLNA GOLIM4 ROBO2 LTBP2	2.64e-04	192	72	4	8171a60df481195c39a7f740effcae8e4deb6ca7
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	FAT3 ROBO2 SPARCL1 LTBP2	2.64e-04	192	72	4	99ce9e3c4c50cf64ebb62145f2b5420efa0db309
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ROBO2 SPARCL1 LTBP2 KCNK4	2.64e-04	192	72	4	b9e4585bea280ca0ae159f0c6a2bf7b88a15a6e6
ToppCell	COPD-Stromal-Myofibroblast\|Stromal / Disease state, Lineage and Cell class	FAT3 ROBO2 LTBP2 PLXNA2	2.64e-04	192	72	4	62904f94dfce430456f05066522cbf9bd29f4d7e
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.4.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	HHIPL2 FIBCD1 AK4 LTBP2	2.69e-04	193	72	4	5bee7abc550ddaa28cbb3b9ecaf6b924ab175de0
ToppCell	E15.5-Mesenchymal-myocytic_cell-aortic_smooth_muscle_cell\|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	FLNA ROBO2 SPARCL1 LTBP2	2.69e-04	193	72	4	e787e618f6e8a1e22be366ce606bf78831b60a90
ToppCell	normal_Lymph_Node-B_lymphocytes-GC_B_cells_in_the_DZ\|normal_Lymph_Node / Location, Cell class and cell subclass	NUSAP1 C21orf58 MCM7 CCDC144A	2.69e-04	193	72	4	5ce93860bc60ce6ecfed3a3d985f84e28781eec1
ToppCell	PND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_prolif\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GOLIM4 ROBO2 MCM7 LTBP2	2.69e-04	193	72	4	f25bdd10ef531b8d8441ea84573078b4b1b0f105
Disease	SPARC-like protein 1 measurement	DSPP SPARCL1	8.75e-05	6	72	2	EFO_0008289
Disease	platelet glycoprotein ib alpha chain measurement	AK4 BRAP	2.61e-04	10	72	2	EFO_0020645
Disease	brain connectivity measurement	FAT3 CNOT7 ADAMTS20 ROBO2 PLXNA2 MOV10	4.39e-04	400	72	6	EFO_0005210
Disease	diet measurement, HOMA-B	CYB5B FAT3	9.77e-04	19	72	2	EFO_0004469, EFO_0008111
Disease	acetate measurement	APMAP AK4	1.08e-03	20	72	2	EFO_0010112
Disease	S-warfarin to R-warfarin ratio measurement	CRACD SLC24A4 GOLIM4	1.64e-03	95	72	3	EFO_0803331
Disease	lysophosphatidylethanolamine 20:4 measurement	LRIG2 MAGI3	2.28e-03	29	72	2	EFO_0010370

Protein segments in the cluster

Peptide	Gene	Start	Entry
NHEPERLGLNGIAET	EPC2	786	Q52LR7
INHLPAETRQEIQEG	BRAP	546	Q7Z569
LVAHAARQEPQGQEI	AMOT	71	Q4VCS5
NLGVIQELVEHGANP	ANKRD16	116	Q6P6B7
ELGQAEPQQRIHVSE	CBLC	321	Q9ULV8
NQQLLGERGEEHSPL	CACNB3	381	P54284
NAEDRGHEIIEPGNQ	ALMS1	3221	Q8TCU4
DHAGPIRVVNIEGVD	AARSD1	191	Q9BTE6
GHNEDVAVVQEDGPQ	DSPP	171	Q9NZW4
ENQLVGPESIAHIGD	APMAP	96	Q9HDC9
DGLNQQIPRKENGEH	CCDC144CP	506	Q8IYA2
LRPGVQEDSREHGQV	ZNF436-AS1	51	Q8NC38
GAHLRPEGQNLVQEE	DUS3L	181	Q96G46
GRVLVNLNHPPEEEN	RAD54L2	246	Q9Y4B4
LEDNENQVVHPSVRG	ADAMTS20	1291	P59510
HLPGVGQNLQDHLEI	CHDH	326	Q8NE62
LPHVERNLQEIQQAG	NUP93	26	Q8N1F7
LQNGRHENIENGNVP	SLC24A4	366	Q8NFF2
QIDVVQPGADQHGLV	QRICH2	531	Q9H0J4
NPNEGATVEIHLEGR	FKBP5	161	Q13451
NGRHPVIDVLLGEQD	MSH3	861	P20585
RIHVGDQIVEINGEP	MAGI3	1061	Q5TCQ9
EEQHNLPVIGAGSVD	ERVS71-1	86	P61550
HQNGLALPVVEEGEV	GPBP1L1	366	Q9HC44
ALEQPHEQQAQRELG	KCNK4	26	Q9NYG8
HGIDDVTGEPLVQQE	AK4	146	P27144
GGPHLQVQEDGQVLR	HMCN2	1481	Q8NDA2
EQQSPDIAQGVHLDR	MAT2A	111	P31153
QEQRLPTGEDAPQEH	HPS4	221	Q9NQG7
HERGNPELEQQARLG	MCF2L2	601	Q86YR7
DHPVLRELEVQGNGQ	PLXNA2	1331	O75051
VPGDRLVEINGHNVE	MYO18A	271	Q92614
HLGQQGADEEVIPVT	KIAA1549L	1236	Q6ZVL6
ISNQEEAERQPLGHV	NUSAP1	71	Q9BXS6
ELPVRSIHLEGDGQQ	HAUS8	246	Q9BT25
LVEGENTRIAQPGDH	MCM7	256	P33993
QRQAELEEGRPQHQE	GOLIM4	461	O00461
LELERIGPQHQAGSD	CNOT7	216	Q9UIV1
HADGERPNVLENLDN	ICE2	536	Q659A1
VVDNQGLGLPVDIQH	C2orf83	26	Q53S99
EEGIQKLQRAIQEHP	GNPAT	141	O15228
EQERQNVEGGPEGLH	C21orf58	106	P58505
HGGKAPLRVQVQDNE	FLNA	701	P21333
RLAQDPQHEQGGLES	CRACD	176	Q6ZU35
QEREQLQPHENGEGN	ITGAV	1031	P06756
LNEHPGGEEVLLEQA	CYB5B	56	O43169
GHLVTQVQAIDPDDG	FAT3	2616	Q8TDW7
DFHIGDRVLIGNVQP	CEP350	2496	Q5VT06
LEQRDGTQQAVPLEH	LTBP2	321	Q14767
EHQAQPRLVGDQEQE	FIBCD1	121	Q8N539
LGLHVNEEEQERPVG	C5orf49	81	A4QMS7
DGLNQQIPRKENGEH	CCDC144A	556	A2RUR9
VILEIEEPASNHNGG	HHIPL2	326	Q6UWX4
HRSLEPQGQVAEQEE	PARP10	661	Q53GL7
ERLPGGENQPQEHSI	NBR1	781	Q14596
VEVQGPHEARDGQLL	MOV10	126	Q9HCE1
QEHGPQAITGLEPRE	PPP1R32	136	Q7Z5V6
NDGNAILREIQVQHP	CCT3	61	P49368
VPGVNIEEHLQLRQE	MYCBP2	846	O75592
NVIHPDVVVNGGQDQ	IARS2	671	Q9NSE4
LEHQEGQLGLPEQQV	IVL	356	P07476
ERHDGGLQANPVEVQ	ISL1	271	P61371
HGIIAEENKNLQPQG	TBC1D9B	116	Q66K14
IDILPHGDQTQIGER	ABCC8	811	Q09428
REEHQGENLDENLVP	AMFR	391	Q9UKV5
IEAGELNHQNGEPTE	ZSCAN32	361	Q9NX65
LQAGQQDLEPAIREH	PROM2	276	Q8N271
KEPGEVGTHNDNQER	SPARCL1	206	Q14515
SRDIDPHVEGQIGQV	TTBK2	856	Q6IQ55
DINAEQLPGREHLNE	PLAA	331	Q9Y263
PAQGVDHRQVQKELG	ROBO2	621	Q9HCK4
GNHRPNPDVDQLEET	TMEM174	206	Q8WUU8
RIHTGDKNVQEPEQG	ZKSCAN3	446	Q9BRR0
HQNVQLPREGQEDQG	PTBP1	411	P26599
KVQVGHLQRVDPQDG	XIRP1	396	Q702N8
QLHQNEGLAGREPDC	LRIG2	1021	O94898