Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	helicase activity	MCM8 MCM7 NAV2 DDX39B DHX57 CHD8 DDX55 MTREX DDX39A	1.16e-04	158	237	9	GO:0004386
GeneOntologyMolecularFunction	3',5'-cyclic-AMP phosphodiesterase activity	PDE3A PDE6A PDE5A PDE7B	1.20e-04	22	237	4	GO:0004115
GeneOntologyMolecularFunction	3',5'-cyclic-GMP phosphodiesterase activity	PDE3A PDE6A PDE5A PDE7B	1.71e-04	24	237	4	GO:0047555
GeneOntologyMolecularFunction	3',5'-cyclic-nucleotide phosphodiesterase activity	PDE3A PDE6A PDE5A PDE7B	2.01e-04	25	237	4	GO:0004114
GeneOntologyMolecularFunction	cyclic-nucleotide phosphodiesterase activity	PDE3A PDE6A PDE5A PDE7B	2.74e-04	27	237	4	GO:0004112
GeneOntologyMolecularFunction	fibroblast growth factor binding	ITGAV ITGB3 GLG1 FGFBP1	2.74e-04	27	237	4	GO:0017134
GeneOntologyMolecularFunction	MutSbeta complex binding	MCM8 MUTYH	4.18e-04	3	237	2	GO:0032408
GeneOntologyMolecularFunction	MutLbeta complex binding	MCM8 MUTYH	4.18e-04	3	237	2	GO:0032406
GeneOntologyMolecularFunction	microtubule minus-end binding	HAUS4 TUBGCP3 MACF1	6.76e-04	15	237	3	GO:0051011
GeneOntologyMolecularFunction	ATP hydrolysis activity	MCM8 ABCA13 MCM7 NAV2 DDX39B KIF13B DHX57 CHD8 DDX55 ATP2C1 MACF1 ATP1A2 MTREX DDX39A	8.41e-04	441	237	14	GO:0016887
GeneOntologyMolecularFunction	fibronectin binding	ITGA3 ITGAV ITGB3 HSD17B12	1.04e-03	38	237	4	GO:0001968
GeneOntologyMolecularFunction	phosphoric diester hydrolase activity	PDE3A PDE6A ENPP2 PLCL1 PDE5A PDE7B	1.05e-03	97	237	6	GO:0008081
GeneOntologyMolecularFunction	ATP-dependent activity	MCM8 ABCA13 MCM7 MYO5C NAV2 DDX39B KIF13B DHX57 CHD8 DDX55 DNAH1 ATP2C1 MYH14 MACF1 ATP1A2 MTREX DDX39A	1.11e-03	614	237	17	GO:0140657
GeneOntologyMolecularFunction	nucleoside-triphosphatase regulator activity	STARD13 DOCK4 ARHGEF38 GBP3 DOCK5 DLC1 SYDE2 HERC1 SEC23A PREX2 DENND4C ARHGEF10L ARAP3 EIF2B1 RALGPS1	1.13e-03	507	237	15	GO:0060589
GeneOntologyMolecularFunction	GTPase regulator activity	STARD13 DOCK4 ARHGEF38 GBP3 DOCK5 DLC1 SYDE2 HERC1 SEC23A PREX2 DENND4C ARHGEF10L ARAP3 EIF2B1 RALGPS1	1.13e-03	507	237	15	GO:0030695
GeneOntologyCellularComponent	filopodium membrane	ITGA3 ITGAV ITGB3 VASP	8.28e-05	21	237	4	GO:0031527
GeneOntologyCellularComponent	actin cytoskeleton	GBP3 DAPK1 MYO5C ACTL7A DOCK5 DLC1 DST MPP4 AHNAK VASP CNN2 CLIC4 GAS2L2 PDLIM1 MYH14 MACF1 CORIN MYO16	1.08e-04	576	237	18	GO:0015629
GeneOntologyCellularComponent	alphav-beta3 integrin-PKCalpha complex	ITGAV ITGB3	3.81e-04	3	237	2	GO:0035866
GeneOntologyCellularComponent	alphav-beta3 integrin-HMGB1 complex	ITGAV ITGB3	3.81e-04	3	237	2	GO:0035868
GeneOntologyCellularComponent	integrin alphaIIb-beta3 complex	ITGA2B ITGB3	3.81e-04	3	237	2	GO:0070442
GeneOntologyCellularComponent	integrin alphav-beta3 complex	ITGAV ITGB3	3.81e-04	3	237	2	GO:0034683
GeneOntologyCellularComponent	integrin complex	ITGA2B ITGA3 ITGAV ITGB3	4.51e-04	32	237	4	GO:0008305
GeneOntologyCellularComponent	protein complex involved in cell adhesion	ITGA2B ITGA3 ITGAV ITGB3 LGALS1	5.46e-04	59	237	5	GO:0098636
GeneOntologyCellularComponent	alphav-beta3 integrin-IGF-1-IGF1R complex	ITGAV ITGB3	7.57e-04	4	237	2	GO:0035867
GeneOntologyCellularComponent	platelet alpha granule membrane	ITGA2B ITGB3 SELP	8.70e-04	17	237	3	GO:0031092
GeneOntologyCellularComponent	contractile actin filament bundle	DLC1 DST CNN2 GAS2L2 PDLIM1 MYH14	1.39e-03	107	237	6	GO:0097517
GeneOntologyCellularComponent	stress fiber	DLC1 DST CNN2 GAS2L2 PDLIM1 MYH14	1.39e-03	107	237	6	GO:0001725
GeneOntologyCellularComponent	gamma-tubulin complex	TUBGCP3 MZT2B MZT2A	1.65e-03	21	237	3	GO:0000930
GeneOntologyCellularComponent	cortical granule	NLRP5 PADI6	1.86e-03	6	237	2	GO:0060473
GeneOntologyCellularComponent	eukaryotic translation initiation factor 2 complex	EIF2S1 EIF2B1	1.86e-03	6	237	2	GO:0005850
GeneOntologyCellularComponent	host intracellular region	GBP6 GBP3	1.86e-03	6	237	2	GO:0043656
GeneOntologyCellularComponent	host cell cytoplasm	GBP6 GBP3	1.86e-03	6	237	2	GO:0030430
GeneOntologyCellularComponent	host cell part	GBP6 GBP3	1.86e-03	6	237	2	GO:0033643
GeneOntologyCellularComponent	host intracellular part	GBP6 GBP3	1.86e-03	6	237	2	GO:0033646
GeneOntologyCellularComponent	host cell cytoplasm part	GBP6 GBP3	1.86e-03	6	237	2	GO:0033655
GeneOntologyCellularComponent	symbiont-containing vacuole	GBP6 GBP3	1.86e-03	6	237	2	GO:0020003
GeneOntologyCellularComponent	symbiont-containing vacuole membrane	GBP6 GBP3	1.86e-03	6	237	2	GO:0020005
GeneOntologyCellularComponent	lamellipodium membrane	ITGAV ITGB3 VASP	1.89e-03	22	237	3	GO:0031258
GeneOntologyCellularComponent	actomyosin	DLC1 DST CNN2 GAS2L2 PDLIM1 MYH14	2.19e-03	117	237	6	GO:0042641
GeneOntologyCellularComponent	actin filament bundle	DLC1 DST CNN2 GAS2L2 PDLIM1 MYH14	2.29e-03	118	237	6	GO:0032432
MousePheno	biliary cyst	PKD1 PKHD1 AKT1 GAS2L2	1.15e-05	11	196	4	MP:0003266
MousePheno	abnormal placenta morphology	ERG ENPP2 ITGA3 ITGAV TRRAP TRIP12 BIRC6 ITGB3 EBF2 MED24 STK11 DLC1 ZPR1 PKD1 ANKMY2 AKT1 GNPTAB TFAP2C DENND4C ARAP3 DDX39A	1.53e-05	525	196	21	MP:0001711
MousePheno	abnormal placenta vasculature	ERG ITGAV BIRC6 EBF2 MED24 STK11 DLC1 PKD1 AKT1 GNPTAB ARAP3 DDX39A	1.68e-05	192	196	12	MP:0003231
MousePheno	abnormal extraembryonic tissue physiology	ERG USP9X ENPP2 DLGAP5 SUPT20HL2 ITGA2B TRIP12 BIRC6 HEPH MED24 STK11 PKD1 ANKMY2 AKT1 SEC23A ARAP3	2.89e-05	345	196	16	MP:0004264
MousePheno	excessive vocalization	MYT1L CHD8 ATP1A2	5.26e-05	6	196	3	MP:0013140
MousePheno	abnormal extraembryonic tissue morphology	ERG ENPP2 SUPT20HL2 ITGA3 ITGAV TRRAP TRIP12 BIRC6 ITGB3 EBF2 MED24 STK11 DLC1 ZPR1 PKD1 ANKMY2 AKT1 SEC23A EFL1 GNPTAB NSD1 AIP TFAP2C OPA1 DENND4C ARAP3 HSD17B12 DDX39A	6.76e-05	908	196	28	MP:0002086
MousePheno	abnormal neural tube closure	USP9X ENPP2 UNC5B SUPT20HL2 MED24 STK11 DLC1 PKD1 ANKMY2 FLRT3 SEC23A RAD9B OPA1 ATP2C1 GAS2L2 IFT122	8.58e-05	378	196	16	MP:0003720
MousePheno	abnormal placenta labyrinth morphology	ERG ITGAV TRIP12 BIRC6 ITGB3 MED24 STK11 DLC1 AKT1 TFAP2C ARAP3	9.19e-05	194	196	11	MP:0001716
Domain	CH-domain	SPEF2 DST CEP95 NAV2 CNN2 LRCH2 GAS2L2 MACF1	4.55e-06	75	235	8	IPR001715
Domain	P-loop_NTPase	GBP6 SAMD9 MCM8 ABCA13 SPEF2 GBP3 DAPK1 MCM7 MYO5C TRANK1 MPP4 NAV2 PARPBP DDX39B NLRP5 KIF13B EFL1 DHX57 CHD8 DDX55 OPA1 DNAH1 MYH14 MTREX DDX39A MYO16	2.61e-05	848	235	26	IPR027417
Domain	-	DST CEP95 NAV2 CNN2 LRCH2 GAS2L2 MACF1	3.06e-05	71	235	7	1.10.418.10
Domain	CH	SPEF2 DST NAV2 CNN2 LRCH2 GAS2L2 MACF1	3.67e-05	73	235	7	PS50021
Domain	GAR	DST GAS2L2 MACF1	3.82e-05	6	235	3	PS51460
Domain	GAS_dom	DST GAS2L2 MACF1	3.82e-05	6	235	3	IPR003108
Domain	GAS2	DST GAS2L2 MACF1	3.82e-05	6	235	3	PF02187
Domain	-	DST GAS2L2 MACF1	3.82e-05	6	235	3	3.30.920.20
Domain	GAS2	DST GAS2L2 MACF1	3.82e-05	6	235	3	SM00243
Domain	PDEase_I	PDE3A PDE6A PDE5A PDE7B	1.24e-04	21	235	4	PF00233
Domain	PDEASE_I	PDE3A PDE6A PDE5A PDE7B	1.24e-04	21	235	4	PS00126
Domain	PDEase_CS	PDE3A PDE6A PDE5A PDE7B	1.24e-04	21	235	4	IPR023174
Domain	-	PDE3A PDE6A PDE5A PDE7B	1.50e-04	22	235	4	1.10.1300.10
Domain	MCM	MCM8 MCM7 MCMDC2	1.56e-04	9	235	3	SM00350
Domain	MCM_dom	MCM8 MCM7 MCMDC2	1.56e-04	9	235	3	IPR001208
Domain	MCM	MCM8 MCM7 MCMDC2	1.56e-04	9	235	3	IPR031327
Domain	MCM	MCM8 MCM7 MCMDC2	1.56e-04	9	235	3	PF00493
Domain	MOZART2	MZT2B MZT2A	1.58e-04	2	235	2	IPR024332
Domain	MOZART2	MZT2B MZT2A	1.58e-04	2	235	2	PF12926
Domain	CH	DST NAV2 CNN2 LRCH2 GAS2L2 MACF1	1.65e-04	65	235	6	SM00033
Domain	PDEase_catalytic_dom	PDE3A PDE6A PDE5A PDE7B	1.79e-04	23	235	4	IPR002073
Domain	TPR-like_helical_dom	SPAG1 SAMD9 PRPF6 TRRAP GTF3C3 TRANK1 FEM1A AIP TEX11 WDR19 IFT122	1.86e-04	233	235	11	IPR011990
Domain	HD/PDEase_dom	PDE3A PDE6A PDE5A PDE7B	2.13e-04	24	235	4	IPR003607
Domain	HDc	PDE3A PDE6A PDE5A PDE7B	2.13e-04	24	235	4	SM00471
Domain	CH	DST NAV2 CNN2 LRCH2 GAS2L2 MACF1	2.49e-04	70	235	6	PF00307
Domain	Integrin_dom	ITGA2B ITGA3 ITGAV ITGB3	2.51e-04	25	235	4	IPR032695
Domain	-	SPAG1 PRPF6 TRRAP GTF3C3 TRANK1 FEM1A AIP TEX11 WDR19 IFT122	3.03e-04	207	235	10	1.25.40.10
Domain	-	BIRC6 LYST HERC1 WDR17 ANAPC4 PLXNA3 DCAF8L2 WDR27 ARHGEF10L WDR19 NBAS IFT122 LRBA	3.22e-04	333	235	13	2.130.10.10
Domain	LRR_8	LRRC39 LGR4 PKD1 FLRT3 LRCH2 SLITRK4 IGFALS LRRC8B LRRN4	3.23e-04	171	235	9	PF13855
Domain	WD40/YVTN_repeat-like_dom	BIRC6 LYST HERC1 WDR17 ANAPC4 PLXNA3 DCAF8L2 WDR27 ARHGEF10L WDR19 NBAS IFT122 LRBA	3.41e-04	335	235	13	IPR015943
Domain	IPT	EBF2 NFATC4 PKHD1 PLXNA3	3.41e-04	27	235	4	SM00429
Domain	Leu-rich_rpt_typical-subtyp	LRRC39 LGR4 PKD1 FLRT3 LRCH2 SLITRK4 IGFALS LRRC8B LRRN4	4.16e-04	177	235	9	IPR003591
Domain	LRR_TYP	LRRC39 LGR4 PKD1 FLRT3 LRCH2 SLITRK4 IGFALS LRRC8B LRRN4	4.16e-04	177	235	9	SM00369
Domain	LRRNT	LGR4 PKD1 FLRT3 SLITRK4 IGFALS	5.30e-04	53	235	5	PF01462
Domain	TIG	EBF2 NFATC4 PKHD1 PLXNA3	5.89e-04	31	235	4	PF01833
Domain	IPT	EBF2 NFATC4 PKHD1 PLXNA3	6.66e-04	32	235	4	IPR002909
Domain	Leu-rich_rpt	LRRC39 LGR4 PKD1 FLRT3 NLRP5 LRCH2 SLITRK4 ZYG11B IGFALS LRRC8B LRRN4	6.69e-04	271	235	11	IPR001611
Domain	DEK_C	SSH1 SSH2	9.30e-04	4	235	2	PF08766
Domain	DEK_C	SSH1 SSH2	9.30e-04	4	235	2	IPR014876
Domain	Integrin_alpha_C_CS	ITGA2B ITGA3 ITGAV	9.76e-04	16	235	3	IPR018184
Domain	LRR	LRRC39 LGR4 PKD1 FLRT3 LRCH2 SLITRK4 ZYG11B IGFALS LRRC8B	1.03e-03	201	235	9	PS51450
Domain	INTEGRIN_ALPHA	ITGA2B ITGA3 ITGAV	1.40e-03	18	235	3	PS00242
Domain	Integrin_alpha	ITGA2B ITGA3 ITGAV	1.40e-03	18	235	3	IPR000413
Domain	Integrin_alpha-2	ITGA2B ITGA3 ITGAV	1.40e-03	18	235	3	IPR013649
Domain	Integrin_alpha2	ITGA2B ITGA3 ITGAV	1.40e-03	18	235	3	PF08441
Domain	DOCK_N	DOCK4 DOCK5	1.54e-03	5	235	2	PF16172
Domain	Somatomedin_B_chordata	ENPP2 PRG4	1.54e-03	5	235	2	IPR020436
Domain	DOCK_N	DOCK4 DOCK5	1.54e-03	5	235	2	IPR032376
Pathway	WP_INTEGRINMEDIATED_CELL_ADHESION	ITGA2B ITGA3 ITGAV ITGB3 AKT1 AKT2 VASP MAP2K5	2.35e-05	102	163	8	MM15830
Pathway	WP_INTEGRINMEDIATED_CELL_ADHESION	ITGA2B ITGA3 ITGAV ITGB3 AKT1 AKT2 VASP MAP2K5	2.35e-05	102	163	8	M39577
Pathway	WP_SILDENAFIL_TREATMENT	AKT1 AKT2 GUCY1A2 PDE5A	1.29e-04	23	163	4	M46455
Pathway	KEGG_MEDICUS_REFERENCE_ITGA_B_RHOGEF_RHOA_SIGNALING_PATHWAY	ITGA2B ITGA3 ITGAV ITGB3	1.29e-04	23	163	4	M47720
Pathway	KEGG_MEDICUS_REFERENCE_ITGA_B_RHOGAP_RHOA_SIGNALING_PATHWAY	ITGA2B ITGA3 ITGAV ITGB3	1.29e-04	23	163	4	M47537
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	DLGAP5 HEPH KMT2C SULF2 TRANK1 DST NAV2 FLRT3 USP53 SZT2 CHSY1 CHD8 CACHD1 DDX55 ARHGEF10L WDR19 ZNF592 RALGPS1 FAM53B HMGXB3 ATP1A2 MTREX	2.35e-11	529	240	22	14621295
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	MON2 SYNRG ITGA3 TRRAP BIRC6 LYST KMT2C HAUS4 URB1 DST SSH1 AHNAK PKD1 NAV2 PLA2G6 AKT1 AKT2 HERC1 FEM1A PLXNA3 SZT2 NSD1 CHSY1 CHD8 ARHGEF10L VAC14 ARAP3 ZNF592 RALGPS1 HMGXB3 LRBA	4.16e-11	1105	240	31	35748872
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	STARD13 MIS18BP1 DLGAP5 MCM7 PRPF6 TRRAP TRIP12 BIRC6 GTF3C3 HNRNPL CDCA2 URB1 DST AHNAK TUBGCP3 A2ML1 POP1 DDX39B SEC23A SPTLC2 IARS1 DHX57 CLIC4 CHD8 LGALS1 NMD3 ARAP3 MYH14 EIF2S1 MACF1 MTREX DDX39A	1.39e-09	1353	240	32	29467282
Pubmed	Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.	USP9X MCM7 PRPF6 TRRAP TRIP12 GTF3C3 CDCA2 POP1 DDX39B ANAPC4 PML LRCH2 CHD8 DDX55 ZNF592 MYH14 MTREX SLX4	2.12e-09	440	240	18	34244565
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	MYT1L DIPK1A DLGAP5 LGR4 TRIP12 MED24 STK11 KMT2C URB1 INTS14 GLG1 TEDDM1 POP1 HERC1 CPLANE1 PARPBP PML KIF13B FAM234B FRMPD1 NSD1 SPAG5 MACF1 HMGXB3 KDM1B DDX39A SLX4	1.03e-08	1084	240	27	11544199
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	SAMD9 MCM8 RPS6KA1 MPDZ ITGB3 DOCK5 SULF2 DST TUBGCP3 POP1 DHX57 CHD8 DDX55 SPAG5 ARAP3 HSD17B12 IFT122 CRYBG3 MTREX RUBCN	3.24e-08	650	240	20	38777146
Pubmed	The C-type lectin domain of CD62P (P-selectin) functions as an integrin ligand.	ITGA2B ITGAV ITGB3 SELP	7.62e-08	7	240	4	37184585
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	DOCK4 SYNRG MPDZ TRIP12 LYST CDCA2 DLC1 DST CEP95 SYDE2 AHNAK NAV2 NR3C2 PML USP53 KIF13B DENND4C MACF1 FAM53B SSH2 CRYBG3 MTREX	1.67e-07	861	240	22	36931259
Pubmed	Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.	STARD13 GBP3 DAPK1 MCM7 HNRNPL DST GLG1 AHNAK POP1 SEC23A IARS1 CHD8 LGALS1 SPAG5 DNAH1 NBAS MYH14 MACF1 LRBA DDX39A MYO16	2.40e-07	807	240	21	30575818
Pubmed	Relationship of Platelet Glycoprotein IIb/IIIa and CD62P With Hypercoagulable State After Oncologic Surgery.	ITGA2B ITGB3 SELP	3.25e-07	3	240	3	33259230
Pubmed	Factor XIII mediates adhesion of platelets to endothelial cells through alpha(v)beta(3) and glycoprotein IIb/IIIa integrins.	ITGA2B ITGAV ITGB3	3.25e-07	3	240	3	12031826
Pubmed	Akt phosphorylation of deleted in liver cancer 1 abrogates its suppression of liver cancer tumorigenesis and metastasis.	STARD13 DLC1 AKT1	3.25e-07	3	240	3	20600027
Pubmed	Binding of galectin-1 to αIIbβ₃ integrin triggers "outside-in" signals, stimulates platelet activation, and controls primary hemostasis.	ITGA2B ITGB3 LGALS1	3.25e-07	3	240	3	22456341
Pubmed	Identification of p122RhoGAP (deleted in liver cancer-1) Serine 322 as a substrate for protein kinase B and ribosomal S6 kinase in insulin-stimulated cells.	RPS6KA1 DLC1 AKT1	3.25e-07	3	240	3	16338927
Pubmed	A Leu262Pro mutation in the integrin beta(3) subunit results in an alpha(IIb)-beta(3) complex that binds fibrin but not fibrinogen.	ITGA2B ITGAV ITGB3	3.25e-07	3	240	3	10891446
Pubmed	P-selectin expression, but not GPIIb/IIIa activation, is enhanced in the inflammatory stage of Takayasu's arteritis.	ITGA2B ITGB3 SELP	3.25e-07	3	240	3	16636497
Pubmed	The roles of platelet GPIIb/IIIa and alphavbeta3 integrins during HeLa cells adhesion, migration, and invasion to monolayer endothelium under static and dynamic shear flow.	ITGA2B ITGAV ITGB3	3.25e-07	3	240	3	19888429
Pubmed	Shotgun sequencing of the human transcriptome with ORF expressed sequence tags.	ABCA13 USP9X ENPP2 LYST HNRNPL DOCK5 TRANK1 AHNAK A2ML1 NAV2 CPLANE1 PLXNA3 SZT2 SPTLC2 ZSWIM6 HIPK3 STYXL1	3.55e-07	552	240	17	10737800
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	MYT1L BIRC6 HEPH KMT2C URB1 SULF2 DST NAV2 GNPTAB CHD8 MACF1	5.38e-07	225	240	11	12168954
Pubmed	USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.	PDE3A TRIP12 HNRNPL DST AHNAK POP1 HERC1 NSD1 MACF1 LRBA MTREX	7.92e-07	234	240	11	36243803
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	STARD13 SPAG1 PDE6A CES1 SPEF2 PRPF6 TRIP12 LYST CDCA2 STK11 DST AHNAK PKHD1 NAV2 MAP7D2 DDX39B PLXNA3 KIF13B DHX57 AHCYL2 DDX55 GUCY1A2 MYH14 MACF1 PADI6 IFT122 ATP1A2 DDX39A	9.06e-07	1442	240	28	35575683
Pubmed	Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing.	MAGEA11 MCM8 MCM7 STK11 NAV2 AKT1 DDX39B VASP SELP USP53 NR1H3 TEX11 SPAG5 GMCL1 VAC14 TRIM17 ATP1A2 DDX39A MUTYH	1.16e-06	742	240	19	26871637
Pubmed	Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.	STARD13 UNC5B GBP3 DAPK1 PRPF6 CLCC1 HEPH KMT2C INTS14 SRPX2 DLC1 DST SSH1 CEP95 AHNAK TUBGCP3 POP1 PLA2G6 PLCL1 WDR17 GNPTAB NR1H3 SPATS2L TM4SF4 HSD17B12 LRRN4	1.21e-06	1293	240	26	15342556
Pubmed	Entamoeba histolytica cysteine proteinase 5 binds integrin on colonic cells and stimulates NFkappaB-mediated pro-inflammatory responses.	ITGAV ITGB3 AKT1	1.29e-06	4	240	3	20837477
Pubmed	Alpha v beta3 integrin spatially regulates VASP and RIAM to control adhesion dynamics and migration.	ITGAV ITGB3 VASP	1.29e-06	4	240	3	20404115
Pubmed	Integrin alpha3beta1, a novel receptor for alpha3(IV) noncollagenous domain and a trans-dominant Inhibitor for integrin alphavbeta3.	ITGA3 ITGAV ITGB3	1.29e-06	4	240	3	16731529
Pubmed	Unique disulfide bonds in epidermal growth factor (EGF) domains of β3 affect structure and function of αIIbβ3 and αvβ3 integrins in different manner.	ITGA2B ITGAV ITGB3	1.29e-06	4	240	3	22308022
Pubmed	Lack of association between markers in the ITGA3, ITGAV, ITGA6 and ITGB3 and autism in an Irish sample.	ITGA3 ITGAV ITGB3	1.29e-06	4	240	3	21182210
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	MON2 STARD13 SPAG1 MCM7 PRPF6 ITGAV DOCK5 HAUS4 AHNAK ANKMY2 VASP KIF13B LRCH2 IARS1 ZYG11B OPA1 DENND4C SPAG5 WDR19 ERGIC1 PDLIM1 EIF2B1 PDE5A FAM53B IFT122 MUC5AC	1.79e-06	1321	240	26	27173435
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	USP9X PRPF6 TRRAP TRIP12 KMT2C TRANK1 NAV2 HERC1 ANAPC4 SLITRK4 DHX57 OPA1 MIDN ZNF592 LRBA	2.25e-06	497	240	15	36774506
Pubmed	Resveratrol inhibits cardiac hypertrophy via AMP-activated protein kinase and Akt.	STK11 AKT1 AKT2	3.21e-06	5	240	3	18562309
Pubmed	Integrin-linked kinase is required for vitronectin-mediated internalization of Streptococcus pneumoniae by host cells.	ITGAV ITGB3 AKT1	3.21e-06	5	240	3	19118218
Pubmed	Phosphatidylinositol 3-kinase/AKT-mediated activation of estrogen receptor alpha: a new model for anti-estrogen resistance.	RPS6KA1 AKT1 AKT2	3.21e-06	5	240	3	11139588
Pubmed	Basic amino-acid side chains regulate transmembrane integrin signalling.	ITGA2B ITGAV ITGB3	3.21e-06	5	240	3	22178926
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	USP9X PRPF6 TRRAP TRIP12 BIRC6 GTF3C3 URB1 DST AHNAK POP1 SEC23A NSD1 DHX57 CHD8 MYH14 MACF1 MTREX	3.47e-06	653	240	17	22586326
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	FAM186B TRIP12 BIRC6 HNRNPL DOCK5 KMT2C URB1 DST CEP95 SYDE2 AHNAK POP1 PKD1 PKHD1 IARS1 PDLIM1 ZNF592 PRG4	4.24e-06	736	240	18	29676528
Pubmed	Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.	MCM7 TRRAP TRIP12 BIRC6 GTF3C3 KMT2C HAUS4 SSH1 AHNAK PML CHD8 TFAP2C CCNB1 ZNF592	5.59e-06	469	240	14	27634302
Pubmed	Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.	GBP6 RPS6KA1 MRPL30 TRRAP LYST STK11 DST NFATC4 AKT1 AKT2 CPLANE1 ANAPC4 AIP LGALS1 CCNB1 HIPK3 EIF2B1 SLC4A4 MAP2K5 PDE7B	6.05e-06	910	240	20	36736316
Pubmed	Mouse screen reveals multiple new genes underlying mouse and human hearing loss.	MYT1L STARD13 MIS18BP1 DIPK1A ARHGEF38 KDM4E TRRAP C3orf20 GLG1 PLA2G6 AKT2 HERC1 SEC23A KIF13B USP30 SLITRK4 DDX55 DENND4C IDO2 GAS2L2 MYH14 TRIM17 HMGXB3 SLX4	6.21e-06	1242	240	24	30973865
Pubmed	Polymorphisms in predicted microRNA-binding sites in integrin genes and breast cancer: ITGB4 as prognostic marker.	ITGA3 ITGAV ITGB3	6.39e-06	6	240	3	18550570
Pubmed	Integrin αIIb (CD41) plays a role in the maintenance of hematopoietic stem cell activity in the mouse embryonic aorta.	ITGA2B ITGAV ITGB3	6.39e-06	6	240	3	23789102
Pubmed	Cell cycle-dependent phosphorylation regulates RECQL4 pathway choice and ubiquitination in DNA double-strand break repair.	USP9X MRPL30 MPDZ MCM7 TRRAP GTF3C3 HNRNPL POP1 ANKMY2 DDX39B CNN2 SEC23A ANAPC4 IARS1 ERVK13-1 DHX57 AIP OPA1 CCNB1 NMD3 EIF2S1 EIF2B1 HSD17B12 MTREX PRG4	6.77e-06	1335	240	25	29229926
Pubmed	Defining the membrane proteome of NK cells.	USP9X MCM7 PRPF6 BIRC6 CLCC1 HNRNPL GLG1 AHNAK TUBGCP3 CNN2 IARS1 CHSY1 DDX55 OPA1 NMD3 ERGIC1 NBAS ATP2C1 MYH14 EIF2S1 IFT122 LRBA DDX39A	7.23e-06	1168	240	23	19946888
Pubmed	A high-throughput approach for measuring temporal changes in the interactome.	MON2 PDE3A USP9X RPS6KA1 MCM7 BIRC6 PARP6 ZPR1 AHNAK POP1 ANKMY2 HERC1 DDX39B VASP CNN2 SEC23A EFL1 IARS1 AIP LGALS1 PDLIM1 MYH14 EIF2S1 MACF1 LRBA DDX39A	9.98e-06	1455	240	26	22863883
Pubmed	LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.	USP9X TRIP12 GTF3C3 CLCC1 MED24 URB1 SEC23A FAM234B SPTLC2 IARS1 CHSY1 CACHD1 OPA1 SPAG5 CCNB1 NMD3 VAC14 ATP2C1 EIF2S1 HSD17B12	1.00e-05	942	240	20	31073040
Pubmed	Role of integrins during fertilization in mammals.	ITGA3 ITGAV ITGB3	1.11e-05	7	240	3	10091056
Pubmed	Mapping the mammalian ribosome quality control complex interactome using proximity labeling approaches.	MON2 DOCK4 RPS6KA1 MRPL30 HAUS4 VASP CLIC4 AIP MYH14	1.24e-05	202	240	9	29540532
Pubmed	Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.	PDE3A DLGAP5 MRPL30 LGR4 ITGA3 ITGAV TRRAP TRIP12 BIRC6 DST GLG1 AHNAK POP1 CNN2 IARS1 AIP DDX55 LGALS1 CCNB1 ERGIC1 SPATS2L HSD17B12 MACF1 DDX39A	1.27e-05	1297	240	24	33545068
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	MON2 DOCK4 SYNRG MIS18BP1 USP9X MCM7 HAUS4 PML KIF13B AIP MACF1 CRYBG3 MTREX SLX4 ZMYM6	1.67e-05	588	240	15	38580884
Pubmed	Estrogen-dependent uterine secretion of osteopontin activates blastocyst adhesion competence.	ITGA2B ITGA3 ITGAV ITGB3	1.77e-05	23	240	4	23152823
Pubmed	Macrophage-induced integrin signaling promotes Schlemm's canal formation to prevent intraocular hypertension and glaucomatous optic neuropathy.	ITGAV ITGB3 AKT1	1.77e-05	8	240	3	38367239
Pubmed	COMP-Ang1 Potentiates EPC Treatment of Ischemic Brain Injury by Enhancing Angiogenesis Through Activating AKT-mTOR Pathway and Promoting Vascular Migration Through Activating Tie2-FAK Pathway.	ITGAV ITGB3 AKT1	1.77e-05	8	240	3	25792870
Pubmed	Knockout and knockin of the beta1 exon D define distinct roles for integrin splice variants in heart function and embryonic development.	ITGA3 ITGAV ITGB3	1.77e-05	8	240	3	9553049
Pubmed	The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.	USP9X MCM7 DST AHNAK MAP7D2 DDX39B IARS1 NSD1 CHD8 MACF1 HMGXB3	2.21e-05	332	240	11	37433992
Pubmed	Overview of PDEs and their regulation.	PDE3A PDE6A PDE5A PDE7B	2.50e-05	25	240	4	17307970
Pubmed	Integrin recognition of different cell-binding fragments of laminin (P1, E3, E8) and evidence that alpha 6 beta 1 but not alpha 6 beta 4 functions as a major receptor for fragment E8.	ITGA3 ITGAV ITGB3	2.64e-05	9	240	3	1693624
Pubmed	KSHV attachment and entry are dependent on αVβ3 integrin localized to specific cell surface microdomains and do not correlate with the presence of heparan sulfate.	ITGA3 ITGAV ITGB3	2.64e-05	9	240	3	25063885
Pubmed	Platelet alpha-granules.	ITGA2B ITGB3 SELP	2.64e-05	9	240	3	8467233
Pubmed	Characterization of integrin engagement during defined human embryonic stem cell culture.	ITGA3 ITGAV ITGB3	2.64e-05	9	240	3	19933311
Pubmed	Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.	PRPF6 TRRAP TRIP12 GTF3C3 HNRNPL URB1 TUBGCP3 A2ML1 POP1 IARS1 DDX55 SPATS2L ZNF592 MYH14 EIF2S1 LRRC8B MTREX DDX39A	2.78e-05	847	240	18	35850772
Pubmed	Congenital Hepatic Fibrosis Overview ─ RETIRED CHAPTER, FOR HISTORICAL REFERENCE ONLY	PKD1 PKHD1 CPLANE1 WDR19 IFT122	2.99e-05	52	240	5	20301743
Pubmed	Perlecan regulates pericyte dynamics in the maintenance and repair of the blood-brain barrier.	ITGA2B ITGA3 ITGAV ITGB3	3.43e-05	27	240	4	31541017
Pubmed	KAP1 facilitates reinstatement of heterochromatin after DNA replication.	MCM7 PRPF6 TRRAP TRIP12 BIRC6 HNRNPL DDX39B KIF13B EFL1 ERGIC1 NBAS EIF2S1 LRBA ATP1A2 MTREX DDX39A	3.54e-05	704	240	16	29955894
Pubmed	Oscillatory flow-induced proliferation of osteoblast-like cells is mediated by alphavbeta3 and beta1 integrins through synergistic interactions of focal adhesion kinase and Shc with phosphatidylinositol 3-kinase and the Akt/mTOR/p70S6K pathway.	ITGAV ITGB3 AKT1	3.76e-05	10	240	3	19889638
Pubmed	Role of scaffold protein afadin dilute domain-interacting protein (ADIP) in platelet-derived growth factor-induced cell movement by activating Rac protein through Vav2 protein.	ITGAV ITGB3 AKT1	3.76e-05	10	240	3	22027834
Pubmed	CDK5RAP2 stimulates microtubule nucleation by the gamma-tubulin ring complex.	TUBGCP3 MZT2B MZT2A	3.76e-05	10	240	3	21135143
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	MCM7 BIRC6 GTF3C3 DST AHNAK ATF7IP2 CHD8 DENND4C SPAG5 ZNF592 CRYBG3 LRBA	3.83e-05	418	240	12	34709266
Pubmed	A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.	MYT1L ERG NDRG3 BIRC6 KMT2C HOXD3 NFATC4 ZPR1 NR3C2 PLXNA3 NR1H3 AIP TFAP2C MACF1 HMGXB3 RFPL2	3.85e-05	709	240	16	22988430
Pubmed	A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.	SYNRG MCM8 USP9X GTF3C3 HAUS4 TUBGCP3 VASP SEC23A ANAPC4 AHCYL2 DENND4C CCNB1 NMD3 VAC14 ARAP3 EIF2S1 EIF2B1 FAM53B SSH2 MTREX	3.96e-05	1038	240	20	26673895
Pubmed	A protein interaction landscape of breast cancer.	DOCK4 USP9X STK11 DST NAV2 AKT1 AKT2 ANAPC4 SPTLC2 CLIC4 SPAG5 CCNB1 ATP2C1 MACF1 MTREX	3.96e-05	634	240	15	34591612
Pubmed	Different functions of AKT1 and AKT2 in molecular pathways, cell migration and metabolism in colon cancer cells.	AKT1 AKT2	4.74e-05	2	240	2	27878243
Pubmed	Cardiac αVβ3 integrin expression following acute myocardial infarction in humans.	ITGAV ITGB3	4.74e-05	2	240	2	27927700
Pubmed	Intracranial microenvironment reveals independent opposing functions of host alphaVbeta3 expression on glioma growth and angiogenesis.	ITGAV ITGB3	4.74e-05	2	240	2	17028191
Pubmed	Expression profiling reveals genes associated with transendothelial migration of tumor cells: a functional role for alphavbeta3 integrin.	ITGAV ITGB3	4.74e-05	2	240	2	17621633
Pubmed	Adipocyte Mineralocorticoid Receptor Activation Leads to Metabolic Syndrome and Induction of Prostaglandin D2 Synthase.	PTGDS NR3C2	4.74e-05	2	240	2	25966493
Pubmed	BAY 1125976, a selective allosteric AKT1/2 inhibitor, exhibits high efficacy on AKT signaling-dependent tumor growth in mouse models.	AKT1 AKT2	4.74e-05	2	240	2	27699769
Pubmed	Alpha(v)beta(3) integrin engagement enhances cell invasiveness in human multiple myeloma.	ITGAV ITGB3	4.74e-05	2	240	2	12161360
Pubmed	Integrin alphaVbeta3 Binds to the RGD motif of glycoprotein B of Kaposi's sarcoma-associated herpesvirus and functions as an RGD-dependent entry receptor.	ITGAV ITGB3	4.74e-05	2	240	2	18045938
Pubmed	A mutation in the β3 cytoplasmic tail causes variant Glanzmann thrombasthenia by abrogating transition of αIIb β3 to an active state.	ITGA2B ITGB3	4.74e-05	2	240	2	22136613
Pubmed	Hypoxia impairs agonist-induced integrin αIIbβ3 activation and platelet aggregation.	ITGA2B ITGB3	4.74e-05	2	240	2	28790378
Pubmed	Association of platelet ITGA2B and ITGB3 polymorphisms with ex vivo antiplatelet effect of ticagrelor in healthy Chinese male subjects.	ITGA2B ITGB3	4.74e-05	2	240	2	24474638
Pubmed	Isoform-Specific Role of Akt in Oral Squamous Cell Carcinoma.	AKT1 AKT2	4.74e-05	2	240	2	31252679
Pubmed	Genetic and epigenetic changes in the eutopic endometrium of women with endometriosis: association with decreased endometrial αvβ3 integrin expression.	ITGAV ITGB3	4.74e-05	2	240	2	33693877
Pubmed	Full-length αIIbβ3 cryo-EM structure reveals intact integrin initiate-activation intrinsic architecture.	ITGA2B ITGB3	4.74e-05	2	240	2	38579706
Pubmed	Expression of AKT1 along with AKT2 in granulosa-lutein cells of hyperandrogenic PCOS patients.	AKT1 AKT2	4.74e-05	2	240	2	28271235
Pubmed	Integrin alpha IIb beta 3 in a membrane environment remains the same height after Mn2+ activation when observed by cryoelectron tomography.	ITGA2B ITGB3	4.74e-05	2	240	2	18405917
Pubmed	A novel adaptation of the integrin PSI domain revealed from its crystal structure.	ITGAV ITGB3	4.74e-05	2	240	2	15299032
Pubmed	Immunodiagnosis of platelet activation in immune thrombocytopenia through scFv antibodies cognate to activated IIb3 integrins.	ITGA2B ITGB3	4.74e-05	2	240	2	26301697
Pubmed	Non-cytotoxic cobra cardiotoxin A5 binds to alpha(v)beta3 integrin and inhibits bone resorption. Identification of cardiotoxins as non-RGD integrin-binding proteins of the Ly-6 family.	ITGAV ITGB3	4.74e-05	2	240	2	16407244
Pubmed	Glanzmann thrombasthenia: state of the art and future directions.	ITGA2B ITGB3	4.74e-05	2	240	2	23929305
Pubmed	Influence of αvβ3 integrin on the mechanical properties and the morphology of M21 and K562 cells.	ITGAV ITGB3	4.74e-05	2	240	2	27553273
Pubmed	Clinical disability progression and platelet GP IIb/IIIa values in patients with atopic myelitis.	ITGA2B ITGB3	4.74e-05	2	240	2	22484027
Pubmed	Acf7 (MACF) is an actin and microtubule linker protein whose expression predominates in neural, muscle, and lung development.	DST MACF1	4.74e-05	2	240	2	11002341
Pubmed	Low concentration detergent sclerosants induce platelet activation but inhibit aggregation due to suppression of GPIIb/IIIa activation in vitro.	ITGA2B ITGB3	4.74e-05	2	240	2	22531012
Pubmed	Quantitative gene-expression of the tumor angiogenesis markers vascular endothelial growth factor, integrin alphaV and integrin beta3 in human neuroendocrine tumors.	ITGAV ITGB3	4.74e-05	2	240	2	19212638
Pubmed	Binding of the human cytomegalovirus (HCMV) tegument protein UL69 to UAP56/URH49 is not required for efficient replication of HCMV.	DDX39B DDX39A	4.74e-05	2	240	2	20610707
Pubmed	Akt induces down regulation of MUC5AC production in NCI-H292 human airway epithelial cells cultured on extracellular matrix.	AKT1 MUC5AC	4.74e-05	2	240	2	25036673
Pubmed	Knockout of Akt1/2 suppresses the metastasis of human prostate cancer cells CWR22rv1 in vitro and in vivo.	AKT1 AKT2	4.74e-05	2	240	2	33377281
Pubmed	αvβ3 Integrin drives fibroblast contraction and strain stiffening of soft provisional matrix during progressive fibrosis.	ITGAV ITGB3	4.74e-05	2	240	2	30333317
Pubmed	Integrin activation and matrix binding mediate cellular responses to mechanical stretch.	ITGAV ITGB3	4.74e-05	2	240	2	15760908
Interaction	ANGPTL3 interactions	ITGAV BIRC6 ITGB3 DDX39A	3.46e-06	10	233	4	int:ANGPTL3
Interaction	H2BC9 interactions	ABCA13 ENPP2 DLGAP5 DAPK1 TRRAP CDCA2 SULF2 DST AHNAK ATF7IP2 MAP7D2 DDX39B LRCH2 NSD1 PREX2 DNAH1 ARAP3 PDE5A	4.79e-06	446	233	18	int:H2BC9
Interaction	SGK2 interactions	RPS6KA1 DAPK1 HNRNPL AKT1 AKT2 AIP	9.55e-06	43	233	6	int:SGK2
Interaction	LRRC27 interactions	MCM8 HNRNPL INTS14 WDR19 DDX39A	1.07e-05	26	233	5	int:LRRC27
Interaction	SIRT6 interactions	USP9X MCM7 PRPF6 TRRAP TRIP12 GTF3C3 CDCA2 POP1 MAP7D2 AKT1 DDX39B ANAPC4 PML LRCH2 CHD8 DDX55 ZNF592 MYH14 MTREX SLX4 MUTYH	1.40e-05	628	233	21	int:SIRT6
Interaction	TOP3B interactions	MON2 SYNRG ITGA3 TRRAP BIRC6 LYST KMT2C HAUS4 URB1 DST SSH1 AHNAK PKD1 NAV2 PLA2G6 AKT1 AKT2 HERC1 FEM1A DDX39B SEC23A PLXNA3 SZT2 IARS1 NSD1 CHSY1 DHX57 CHD8 ARHGEF10L VAC14 ARAP3 ZNF592 RALGPS1 HSD17B12 HMGXB3 LRBA	1.49e-05	1470	233	36	int:TOP3B
GeneFamily	Phosphodiesterases	PDE3A PDE6A PDE5A PDE7B	4.83e-05	24	155	4	681
GeneFamily	MCM family	MCM8 MCM7 MCMDC2	5.00e-05	9	155	3	1085
GeneFamily	Slingshot protein phosphatases	SSH1 SSH2	2.18e-04	3	155	2	898
GeneFamily	CD molecules\|Integrin alpha subunits	ITGA2B ITGA3 ITGAV	4.59e-04	18	155	3	1160
GeneFamily	Hyalectan proteoglycans\|V-set domain containing\|Sushi domain containing\|C-type lectin domain containing	CSMD3 SRPX2 SELP PAPPA	1.44e-03	57	155	4	1179
GeneFamily	WD repeat domain containing	LYST HERC1 WDR17 DCAF8L2 WDR27 WDR19 IFT122 LRBA	1.93e-03	262	155	8	362
GeneFamily	EF-hand domain containing\|Plakins	DST MACF1	1.98e-03	8	155	2	939
GeneFamily	PDZ domain containing	MPDZ MPP4 AHNAK FRMPD1 PREX2 PDLIM1	2.00e-03	152	155	6	1220
GeneFamily	WD repeat domain containing\|BEACH domain containing	LYST LRBA	2.53e-03	9	155	2	1230
Coexpression	LAKE_ADULT_KIDNEY_C26_MESANGIAL_CELLS	STARD13 DOCK4 PDE3A DLC1 DST AHNAK ADGRF5 PLCL1 HERC1 USP53 PDE7B	6.56e-07	177	236	11	M39245
Coexpression	MULLIGHAN_MLL_SIGNATURE_2_DN	DAPK1 ITGAV MYO5C MN1 PML GNPTAB CLIC4 TEX11 KLRK1 ATP2C1 HSD17B12 MACF1 LRRC8B	1.67e-06	279	236	13	M16867
Coexpression	LAKE_ADULT_KIDNEY_C2_PODOCYTES	DOCK4 DACH1 ITGAV DOCK5 RNF150 DST AHNAK ZSWIM6 SPATS2L MACF1 PDE7B	3.83e-06	212	236	11	M39221
Coexpression	LAKE_ADULT_KIDNEY_C21_COLLECTING_DUCT_INTERCALATED_CELLS_TYPE_B	DACH1 LGR4 KMT2C RNF150 NR3C2 PLCL1 HERC1 KIF13B	4.37e-06	103	236	8	M39240
Coexpression	MURARO_PANCREAS_DUCTAL_CELL	SPAG1 PDE3A SAMD9 CES1 LGR4 GBP3 DAPK1 ITGA3 ITGAV DST AHNAK UPK1B PKHD1 FLRT3 CXCL5 VASP CNN2 KIF13B GNPTAB CLIC4 ZSWIM6 ERGIC1 SPATS2L NEURL3 PDLIM1 MYH14 MACF1 PDE5A SLC4A4	4.64e-06	1276	236	29	M39173
Coexpression	LAKE_ADULT_KIDNEY_C24_ENDOTHELIAL_CELLS_AEA_AND_DVR	DOCK4 PDE3A ENPP2 DST AHNAK ADGRF5 CLIC4 MACF1 CRYBG3	1.03e-05	152	236	9	M39243
Coexpression	FAN_EMBRYONIC_CTX_ASTROCYTE_2	LGR4 KMT2C DST CACHD1 EDNRB SPATS2L MACF1 ATP1A2 SLC4A4	1.14e-05	154	236	9	M39034
Coexpression	LIU_PROSTATE_CANCER_DN	UNC5B PTGDS LYST HEPH PARP6 DST NAV2 NR3C2 PLCL1 FLRT3 CLIC4 CACHD1 PREX2 LGALS1 PDLIM1 ATP1A2	1.15e-05	493	236	16	M19391
Coexpression	MURARO_PANCREAS_MESENCHYMAL_STROMAL_CELL	PDE3A UNC5B ITGAV ITGB3 SRPX2 SULF2 DLC1 SSH1 AHNAK CNN2 SEC23A IARS1 CHSY1 CLIC4 LGALS1 EDNRB SPATS2L GUCY1A2 PAPPA	1.47e-05	681	236	19	M39175
Coexpression	HE_LIM_SUN_FETAL_LUNG_C3_INTERMEDIATE_LYMPHATIC_ENDO_CELL	UNC5B DAPK1 ITGAV MYO5C DOCK5 SULF2 HOXD3 SSH1 LRCH2 NR1H3 CCNJ EDNRB PDLIM1 PDE7B	1.89e-05	402	236	14	M45754
Coexpression	ZHOU_CELL_CYCLE_GENES_IN_IR_RESPONSE_24HR	MCM8 DLGAP5 MCM7 SULF2 PARPBP SPAG5 CCNB1 EIF2S1	2.05e-05	127	236	8	M2608
Coexpression	HAY_BONE_MARROW_STROMAL	ENPP2 UNC5B PTGDS ITGAV HEPH SRPX2 DLC1 HOXD3 NFATC4 NAV2 FLRT3 PNLIPRP3 CLIC4 CACHD1 THSD7B PREX2 EDNRB GUCY1A2 MYH14 PAPPA	2.30e-05	767	236	20	M39209
Coexpression	LAKE_ADULT_KIDNEY_C13_THICK_ASCENDING_LIMB	LGR4 RNF150 PKHD1 NR3C2 PLCL1 USP53 LRBA PDE7B	2.56e-05	131	236	8	M39232
Coexpression	LAKE_ADULT_KIDNEY_C15_CONNECTING_TUBULE	STARD13 DACH1 LGR4 ITGAV KMT2C PKHD1 NR3C2 SSH2 LRBA	2.63e-05	171	236	9	M39234
Coexpression	LEE_CALORIE_RESTRICTION_NEOCORTEX_DN	USP9X PRPF6 SEC23A PML IARS1 EIF2S1	3.73e-05	69	236	6	M1609
Coexpression	HE_LIM_SUN_FETAL_LUNG_C3_SCG3_POS_LYMPHATIC_ENDOTHELIAL_CELL	UNC5B DAPK1 ITGAV HEPH MYO5C SULF2 HOXD3 NAV2 FLRT3 NR1H3 CCNJ EDNRB NMD3 NBAS PDLIM1 IFT122 PDE7B	3.75e-05	604	236	17	M45760
Coexpression	GINESTIER_BREAST_CANCER_20Q13_AMPLIFICATION_DN	MON2 RPS6KA1 TRRAP PARP6 DDX39B PML SZT2 CCNJ RUBCN	4.66e-05	184	236	9	M19988
Coexpression	CHEMNITZ_RESPONSE_TO_PROSTAGLANDIN_E2_UP	DIPK1A DLGAP5 URB1 MZT2B SPAG5 CCNB1 ARAP3 MZT2A	5.30e-05	145	236	8	M3045
Coexpression	LAKE_ADULT_KIDNEY_C20_COLLECTING_DUCT_INTERCALATED_CELLS_TYPE_A_CORTEX	LGR4 ITGAV ADGRF5 NR3C2 PLCL1 AHCYL2 ZSWIM6 SLC26A7	7.39e-05	152	236	8	M39239
Coexpression	GSE19512_NAUTRAL_VS_INDUCED_TREG_UP	MAGEA11 ERG IMPG1 PTGDS ITGB3 AHNAK UPK1B MN1 FAM234B	7.89e-05	197	236	9	M8361
Coexpression	GSE29618_PRE_VS_DAY7_POST_LAIV_FLU_VACCINE_PDC_DN	CES1 ITGAV ANKMY2 NSD1 AIP NMD3 ZNF592 EIF2B1 ZMYM6	8.21e-05	198	236	9	M5001
Coexpression	GSE24142_DN2_VS_DN3_THYMOCYTE_ADULT_DN	USP9X TRIP12 LYST PKD1 HERC1 IARS1 DHX57 ARHGEF10L EIF2S1	8.53e-05	199	236	9	M4567
Coexpression	GSE17301_ACD3_ACD28_VS_ACD3_ACD28_AND_IFNA2_STIM_CD8_TCELL_DN	DIPK1A ENPP2 DACH1 NDRG3 CLCC1 ATF7IP2 LRRC8B LRBA RUBCN	8.86e-05	200	236	9	M8040
Coexpression	GSE37301_MULTIPOTENT_PROGENITOR_VS_CD4_TCELL_DN	CES1 MCM7 NDRG3 ITGB3 MED24 HERC1 ATP2C1 IGFALS PDLIM1	8.86e-05	200	236	9	M8847
Coexpression	GSE34156_UNTREATED_VS_24H_NOD2_LIGAND_TREATED_MONOCYTE_DN	DOCK4 SULF2 ALAS1 UBE2Z FAM234B CLIC4 NR1H3 LGALS1 KDM1B	8.86e-05	200	236	9	M8682
Coexpression	GSE4748_CTRL_VS_LPS_STIM_DC_3H_UP	STARD13 UNC5B ITGAV AHNAK UBE2Z SEC23A IARS1 NMD3 LRBA	8.86e-05	200	236	9	M6480
Coexpression	LAKE_ADULT_KIDNEY_C14_DISTAL_CONVOLUTED_TUBULE	DACH1 LGR4 RNF150 DST PKHD1 NAV2 NR3C2 PLCL1 LRBA	1.19e-04	208	236	9	M39233
Coexpression	LEE_CALORIE_RESTRICTION_NEOCORTEX_DN	USP9X PRPF6 SEC23A PML IARS1 EIF2S1	1.21e-04	85	236	6	MM684
Coexpression	AIZARANI_LIVER_C29_MVECS_2	ERG PTGDS SULF2 DLC1 AHNAK ADGRF5 SELP CHSY1 PREX2 MIDN PDLIM1	1.37e-04	313	236	11	M39128
Coexpression	GSE7568_CTRL_VS_3H_TGFB_TREATED_MACROPHAGES_WITH_IL4_AND_DEXAMETHASONE_DN	PARP6 CEP95 SYDE2 PKD1 ANAPC4 CHD8 HIPK3 MACF1	1.42e-04	167	236	8	M361
Coexpression	LAZARO_GENETIC_MOUSE_MODEL_HIGH_GRADE_LARGE_CELL_NEUROENDOCRINE_LUNG_CARCINOMA_DN	STARD13 DOCK4 GBP6 ERG DACH1 AHNAK UPK1B ADGRF5 PREX2 ARAP3 GUCY1A2 MACF1 PDE5A ATP1A2	1.60e-04	491	236	14	MM455
Coexpression	AIZARANI_LIVER_C10_MVECS_1	ERG PTGDS DLC1 ADGRF5 CHSY1 CLIC4 EDNRB MIDN ARAP3 PDLIM1	1.75e-04	269	236	10	M39114
CoexpressionAtlas	dev gonad_e13.5_F_MeioticGermCell_Oct_top-relative-expression-ranked_1000	MAGEA11 MIS18BP1 MCM8 USP9X MCMDC2 LYST KMT2C URB1 TRANK1 ATF7IP2 MAP7D2 HERC1 CPLANE1 PARPBP RAD9B TEX11 NMD3 GMCL1 PDE5A SSH2 LRBA KDM1B TCFL5 ZMYM6	1.12e-05	820	231	24	gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_1000
CoexpressionAtlas	FacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_1000_k-means-cluster#3	MIS18BP1 PRPF6 CLCC1 CPLANE1 GNPTAB DHX57 ZYG11B OPA1 WDR19 MACF1 CORIN LRBA SLX4	1.95e-05	291	231	13	Facebase_RNAseq_e10.5_Lateral Nasal Eminence_1000_K3
CoexpressionAtlas	DevelopingGonad_e14.5_ ovary_emap-6699_top-relative-expression-ranked_500	DOCK4 MAGEA11 MIS18BP1 BIRC6 ATF7IP2 MAP7D2 HERC1 DMRT1 CPLANE1 USP53 CHD8 AHCYL2 THSD7B TEX11 TCFL5	2.06e-05	382	231	15	gudmap_developingGonad_e14.5_ ovary_500
CoexpressionAtlas	DevelopingGonad_e18.5_ovary_emap-12283_top-relative-expression-ranked_500	MYT1L DOCK4 MAGEA11 BIRC6 KMT2C MAP7D2 HERC1 CPLANE1 NLRP5 USP53 CHD8 THSD7B TEX11 KDM1B TCFL5	2.40e-05	387	231	15	gudmap_developingGonad_e18.5_ovary_500
CoexpressionAtlas	dev gonad_e13.5_F_MeioticGermCell_Oct_k-means-cluster#1_top-relative-expression-ranked_1000	MCMDC2 HERC1 RAD9B TEX11 KDM1B TCFL5 ZMYM6	3.95e-05	85	231	7	gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_k1_1000
CoexpressionAtlas	kidney_P0_JuxtaGlom_Ren1_k-means-cluster#2_top-relative-expression-ranked_1000	PDE3A DACH1 ITGAV DLC1 PLCL1 CNN2 GUCY1A2 SLC26A7 PDE5A	7.66e-05	163	231	9	gudmap_kidney_P0_JuxtaGlom_Ren1_k2_1000
CoexpressionAtlas	DevelopingGonad_e16.5_epididymis_emap-29702_k-means-cluster#4_top-relative-expression-ranked_1000	BIRC6 KMT2C NAV2 HERC1 CPLANE1 USP53 CHD8 AHCYL2	7.67e-05	127	231	8	gudmap_developingGonad_e16.5_epididymis_1000_k4
CoexpressionAtlas	DevelopingGonad_e18.5_epididymis_emap-13166_k-means-cluster#4_top-relative-expression-ranked_1000	BIRC6 KMT2C HERC1 CPLANE1 USP53 CHD8 AHCYL2	9.22e-05	97	231	7	gudmap_developingGonad_e18.5_epididymis_1000_k4
CoexpressionAtlas	DevelopingGonad_e18.5_ovary_emap-12283_k-means-cluster#1_top-relative-expression-ranked_500	DOCK4 BIRC6 KMT2C MAP7D2 HERC1 THSD7B TEX11 TCFL5	1.12e-04	134	231	8	gudmap_developingGonad_e18.5_ovary_500_k1
CoexpressionAtlas	dev gonad_e11.5_M_PrimGermCell_Oct_k-means-cluster#2_top-relative-expression-ranked_1000	MAGEA11 MIS18BP1 MCM8 DLGAP5 MCM7 CDCA2 ATF7IP2 NMD3 PDE5A LRRN4 DDX39A	1.29e-04	258	231	11	gudmap_dev gonad_e11.5_M_PrimGermCell_Oct_k2_1000
CoexpressionAtlas	DevelopingGonad_e12.5_epididymis_emap-29139_k-means-cluster#5_top-relative-expression-ranked_1000	DOCK4 BIRC6 HERC1 CPLANE1 USP53 CHD8 THSD7B TEX11	1.37e-04	138	231	8	gudmap_developingGonad_e12.5_epididymis_k5_1000
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_top-relative-expression-ranked_500	PDE3A USP9X DACH1 DLC1 DST UPK1B CPLANE1 NSD1 PHYHD1 TFAP2C EDNRB HIPK3 SLC26A7 PDE5A	1.63e-04	408	231	14	DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_500
CoexpressionAtlas	dev gonad_e12.5_F_DevVasOvary_Flk_top-relative-expression-ranked_500	STARD13 DOCK4 ERG UNC5B DLC1 ADGRF5 PLCL1 CNN2 PREX2 EDNRB ARAP3 SSH2 CRYBG3 PDE7B	1.94e-04	415	231	14	gudmap_dev gonad_e12.5_F_gudmap_devVasOvary_Flk_500
CoexpressionAtlas	dev gonad_e13.5_M_GermCell_Oct_k-means-cluster#4_top-relative-expression-ranked_1000	MCMDC2 MAP7D2 HERC1 CPLANE1 TEX11 TCFL5 ZMYM6	2.03e-04	110	231	7	gudmap_dev gonad_e13.5_M_GermCell_Oct_k4_1000
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_top-relative-expression-ranked_1000	PDE3A ERG USP9X DACH1 LGR4 ITGAV TRIP12 DLC1 DST UPK1B CPLANE1 NSD1 PHYHD1 TFAP2C EDNRB SPAG5 HIPK3 SLC26A7 PDE5A SLC4A4 PDE7B	2.06e-04	806	231	21	DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_1000
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k-means-cluster#3_top-relative-expression-ranked_1000	PDE3A USP9X LGR4 TRIP12 DLC1 CPLANE1 NSD1 PHYHD1 EDNRB SPAG5 HIPK3 SLC4A4 PDE7B	2.16e-04	369	231	13	DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k3_1000
CoexpressionAtlas	NK cells, NK.H+.MCMV1.Sp, NK1.1+ TCRb- Ly49H+, Spleen, avg-3	GBP6 MCM7 DOCK5 SULF2 AHNAK PML GNPTAB CHSY1 CLIC4 ZSWIM6 LGALS1 KLRK1 PDE5A	2.21e-04	370	231	13	GSM538300_500
CoexpressionAtlas	DevelopingGonad_P2_ovary_emap-30224_k-means-cluster#3_top-relative-expression-ranked_500	MYT1L BIRC6 MAP7D2 HERC1 TEX11 TCFL5	2.23e-04	79	231	6	gudmap_developingGonad_P2_ovary_500_k3
CoexpressionAtlas	DevelopingGonad_P2_ovary_emap-30224_top-relative-expression-ranked_500	MYT1L BIRC6 SRPX2 MAP7D2 HERC1 CPLANE1 NLRP5 CHD8 TEX11 SLC26A7 PADI6 KDM1B TCFL5	2.79e-04	379	231	13	gudmap_developingGonad_P2_ovary_500
CoexpressionAtlas	DevelopingGonad_e14.5_ ovary_emap-6699_k-means-cluster#2_top-relative-expression-ranked_500	DOCK4 MIS18BP1 BIRC6 THSD7B	2.99e-04	30	231	4	gudmap_developingGonad_e14.5_ ovary_500_k2
CoexpressionAtlas	dev gonad_e13.5_M_InterstitFLeydig_MafB_top-relative-expression-ranked_1000	PDE3A DLGAP5 LGR4 PTGDS HEPH SRPX2 SULF2 TRANK1 DLC1 UPK1B ANKMY2 ALAS1 CNN2 CHSY1 LGALS1 SPATS2L GUCY1A2 SLC26A7 PAPPA PDE5A	3.20e-04	773	231	20	gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_1000
CoexpressionAtlas	DevelopingGonad_e18.5_ovary_emap-12283_top-relative-expression-ranked_1000	MYT1L DOCK4 MAGEA11 BIRC6 KMT2C SRPX2 NAV2 MAP7D2 HERC1 CPLANE1 NLRP5 USP53 SLITRK4 CHD8 AHCYL2 THSD7B TEX11 SLC26A7 KDM1B TCFL5	3.48e-04	778	231	20	gudmap_developingGonad_e18.5_ovary_1000
CoexpressionAtlas	dev gonad_e11.5_M_PrimGermCell_Oct_top-relative-expression-ranked_1000	MAGEA11 MIS18BP1 MCM8 DLGAP5 MCM7 ITGB3 CDCA2 SYDE2 POP1 ATF7IP2 MAP7D2 PML TEX11 TFAP2C CCNB1 NMD3 VAC14 PDE5A LRRN4 DDX39A	3.65e-04	781	231	20	gudmap_dev gonad_e11.5_M_PrimGermCell_Oct_1000
CoexpressionAtlas	kidney_P0_JuxtaGlom_Ren1_top-relative-expression-ranked_1000	PDE3A DIPK1A ENPP2 DACH1 ITGAV ITGB3 DLC1 NFATC4 AFM UPK1B PKHD1 ADGRF5 PLCL1 CNN2 GNPTAB EDNRB GUCY1A2 PDLIM1 SLC26A7 CORIN PDE5A SLC4A4	3.79e-04	905	231	22	gudmap_kidney_P0_JuxtaGlom_Ren1_1000
ToppCell	LPS_only-Endothelial-Endothelial\|LPS_only / Treatment groups by lineage, cell group, cell type	ERG DACH1 GBP3 DLC1 DST ADGRF5 PML SPTLC2 PREX2 EDNRB ARAP3 MACF1	9.70e-10	200	239	12	4bb609a284d4e6066f17470a1736076aa4a1f84c
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	ERG ENPP2 SPEF2 MPDZ BIRC6 KMT2C DLC1 DST ADGRF5 PREX2 ARAP3 MACF1	9.70e-10	200	239	12	dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell	LPS_only-Endothelial\|LPS_only / Treatment groups by lineage, cell group, cell type	ERG DACH1 GBP3 DLC1 DST ADGRF5 PML SPTLC2 PREX2 EDNRB ARAP3 MACF1	9.70e-10	200	239	12	81e76508c9050d533853d5fd2f3097b27613d836
ToppCell	CD8+_Memory_T_cell-CV-7\|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster	MON2 BIRC6 LYST URB1 GLG1 KIF13B GNPTAB NSD1 NBAS MACF1 LRBA	7.52e-09	191	239	11	9454f642c3621370fa23640b631301346b300950
ToppCell	Control_saline-Endothelial-Endothelial-Gen_Cap\|Control_saline / Treatment groups by lineage, cell group, cell type	ERG ENPP2 SPEF2 MPDZ DLC1 DST ADGRF5 PML PREX2 ARAP3 MACF1	1.21e-08	200	239	11	3b97920e1e6e2f09ddba2a861baa9c00c2970f4c
ToppCell	CV-Severe-7\|Severe / Virus stimulation, Condition and Cluster	LYST URB1 DST GLG1 DDX39B KIF13B GNPTAB NSD1 NBAS HSD17B12	4.38e-08	177	239	10	82fdd6185b368f54f03de389427cbe3071d21a99
ToppCell	Calu_3-infected\|Calu_3 / Cell line, Condition and Strain	SAMD9 USP9X GBP3 TRIP12 KMT2C TRANK1 DST PML CHD8 NEURL3	6.00e-08	183	239	10	8f7f5000645f24f20a8d7700c4df1f8953a1780b
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1-6_FGFR3_ETNPPL\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PTGDS HEPH DOCK5 NFATC4 AHNAK PHYHD1 PREX2 EDNRB ATP1A2 SLC4A4	7.36e-08	187	239	10	4d2115a05ec36dd179ca1d4a525f2d4501aea557
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DACH1 LGR4 MYO5C RNF150 HOXD3 PKHD1 NAV2 NR3C2 CACHD1 LRBA	8.13e-08	189	239	10	975c0f079903ae36b0ffa54e86294d42ec7697de
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DACH1 LGR4 MYO5C RNF150 HOXD3 PKHD1 NAV2 NR3C2 CACHD1 LRBA	8.13e-08	189	239	10	7eb8f5a951e80f1cfac4d7c9eb169f4eb100c917
ToppCell	PND07-28-samps-Mesenchymal-Matrix_fibroblast-FB-3\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	STARD13 DOCK4 DLC1 UPK1B NAV2 CNN2 PREX2 SPATS2L MACF1 ATP1A2	8.54e-08	190	239	10	1196b8ea2c44c7c80f5ee589dd517e6a413f2077
ToppCell	(5)_Fibroblasts-(5)_Fibroblast-C_(Myofibroblast)\|(5)_Fibroblasts / Lung cell shreds - cell class (v4) and cell subclass (v4)	DOCK4 CES1 ENPP2 PTGDS HEPH DST USP53 MACF1 PDE5A PRG4	8.54e-08	190	239	10	71e112dfb8c3190fe0286b45a046ea789eb6a8db
ToppCell	COPD-Endothelial-VE_Arterial\|Endothelial / Disease state, Lineage and Cell class	PDE3A ERG ENPP2 DACH1 LYST SELP KIF13B CHSY1 CLIC4 PREX2	8.97e-08	191	239	10	ef16ad1c1cd2c0c0377957398c98775b62a81754
ToppCell	Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)\|World / Lineage, Cell type, age group and donor	DAPK1 ITGA3 MYO5C DLC1 PKHD1 NAV2 ADGRF5 NR3C2 CACHD1 MYH14	8.97e-08	191	239	10	d3733c8c4bda70c4390e5601fdda6188a64be944
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6\|TCGA-Prostate / Sample_Type by Project: Shred V9	SYNRG USP9X BIRC6 GTF3C3 CPLANE1 SPTLC2 DENND4C LRRC8B CRYBG3 KDM1B	9.89e-08	193	239	10	abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	DOCK4 DACH1 SRPX2 DLC1 DST NAV2 USP53 PREX2 MACF1 PDE5A	9.89e-08	193	239	10	99525545552b371c86b18b6ea6f4897dc6e9a9ec
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK4 ERG DLC1 SSH1 ADGRF5 SELP CLIC4 PREX2 ARAP3 PDLIM1	1.14e-07	196	239	10	7cbb19108b4553ef60ef5c230a29de1662c02efe
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Endothelial\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK4 ERG DLC1 SSH1 ADGRF5 SELP CLIC4 PREX2 ARAP3 PDLIM1	1.14e-07	196	239	10	4cd1e6b7a791e11a40b19f971b7011bd11fe6273
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PDE3A ERG HEPH SRPX2 DLC1 CLIC4 PREX2 EDNRB GUCY1A2 PDLIM1	1.14e-07	196	239	10	3a6c942e2907aa07b5e12dbf9019d18f7bfca507
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PDE3A ERG HEPH SRPX2 DLC1 CLIC4 PREX2 EDNRB GUCY1A2 PDLIM1	1.14e-07	196	239	10	bba88e91cd3e3a6f5a9b443e3a4da33c5b455e70
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK4 ERG ENPP2 DLC1 ADGRF5 SELP CACHD1 PREX2 ARAP3 PDLIM1	1.14e-07	196	239	10	e224338490691d92c1f70b57112fabdcc92b06a9
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK4 ERG ENPP2 DLC1 ADGRF5 SELP CACHD1 PREX2 ARAP3 PDLIM1	1.20e-07	197	239	10	c10dd1aaec01fb662eac83dfde90e3e426665d65
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK4 ERG ENPP2 DLC1 ADGRF5 SELP CACHD1 PREX2 ARAP3 PDLIM1	1.20e-07	197	239	10	2844dbcd0a673ed81c99920aa45858651a00736d
ToppCell	LPS_only-Endothelial-Endothelial-FOXM1\|LPS_only / Treatment groups by lineage, cell group, cell type	MIS18BP1 DLGAP5 MPDZ NAV2 ANKMY2 PARPBP DHX57 SPAG5 CCNB1 MIDN	1.20e-07	197	239	10	038fd92750257d43d5e980fd06d77742b543f11a
ToppCell	normal_Lung-Fibroblasts-COL13A1+_matrix_FBs\|Fibroblasts / Location, Cell class and cell subclass	CES1 ENPP2 PTGDS DST NAV2 CNN2 HSD17B12 MACF1 PDE5A PRG4	1.26e-07	198	239	10	e0e47cf65774191981840b22905b2094b95abe0f
ToppCell	IPF-Endothelial-VE_Peribronchial\|Endothelial / Disease state, Lineage and Cell class	DOCK4 ERG ENPP2 MYO5C DLC1 NAV2 CACHD1 PREX2 HIPK3 LRRC8B	1.26e-07	198	239	10	b8bd1ba268480f54451648e01631b615a3401144
ToppCell	Tracheal-NucSeq\|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations	MON2 STARD13 BIRC6 KMT2C NR3C2 HERC1 ZSWIM6 NBAS SSH2 LRBA	1.32e-07	199	239	10	94b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCell	LPS_IL1RA-Endothelial\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	ERG DACH1 DLC1 DST AHNAK ADGRF5 CLIC4 EDNRB ARAP3 MACF1	1.38e-07	200	239	10	5c092b2ecc081b5d04476c56333c338cd89ab984
ToppCell	LPS_IL1RA-Endothelial-Endothelial\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	ERG DACH1 DLC1 DST AHNAK ADGRF5 CLIC4 EDNRB ARAP3 MACF1	1.38e-07	200	239	10	72ea9882a8ed26fa1534aeb6ba0d1897dccc20c5
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-Gen_Cap\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	ERG ENPP2 SPEF2 DLC1 DST ADGRF5 SPTLC2 PREX2 ARAP3 MACF1	1.38e-07	200	239	10	a2b9d1cd291d17abddc3ee2e242121412c864b8b
ToppCell	PBMC-Mild-Myeloid-cDC-cDC-cDC_4\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	DIPK1A LGR4 DST TUBGCP3 RAD9B PHYHD1 SPATS2L PADI6 PDE7B	1.49e-07	153	239	9	91e9d70a5d3f6fd68c284ed0cc113f03d7d1e10b
ToppCell	PBMC-Mild-Myeloid-cDC-cDC-cDC_4\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	DIPK1A LGR4 DST TUBGCP3 RAD9B PHYHD1 SPATS2L PADI6 PDE7B	1.49e-07	153	239	9	f17f62646633cf95c810dcd5328978058741b276
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PDE3A UNC5B HEPH DLC1 TEDDM1 PLCL1 USP53 ATP1A2 PDE7B	3.64e-07	170	239	9	876b84740e15399bfff2b9c7f0b80fd759bbdb3f
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PDE3A UNC5B HEPH DLC1 TEDDM1 PLCL1 USP53 ATP1A2 PDE7B	3.64e-07	170	239	9	1f8738acf439d893880db7e1fdc9b3615ca00c39
ToppCell	droplet-Heart-nan-3m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDE3A PRPF6 LYST AHNAK NR3C2 KIF13B NSD1 MACF1 ATP1A2	4.87e-07	176	239	9	749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCell	droplet-Limb_Muscle-MUSCLE-30m\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GBP6 ERG DACH1 GBP3 LYST NR3C2 KIF13B NSD1 PREX2	5.35e-07	178	239	9	01dafd19de04eff459253eaa9a35debf8f3deedf
ToppCell	3'_v3-bone_marrow-Hematopoietic_Erythro-Mega-Erythrocytic-Meg\|bone_marrow / Manually curated celltypes from each tissue	PDE3A ITGA2B ITGB3 DLC1 SELP CCNB1 PDLIM1 PDE5A LRRN4	5.88e-07	180	239	9	44ba37bead1ac39bce4d3eef00961063c50ced0d
ToppCell	PND01-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYT1L MIS18BP1 DLGAP5 DACH1 CDCA2 ADGRF5 PARPBP CCNB1 ARAP3	5.88e-07	180	239	9	b35a8c6169f4b548b912af005e92ae7c6596f376
ToppCell	facs-Kidney-nan-3m\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA13 USP9X PTGDS HNRNPL DST ADGRF5 FLRT3 MIDN MTREX	6.45e-07	182	239	9	4c5d14e33ebdf117b5aa9e2f57aaa89aa51f72bf
ToppCell	COVID-19-Heart-EC_+_Pericyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PDE3A ERG DACH1 EBF2 DLC1 PLCL1 PREX2 GUCY1A2 PDE7B	6.45e-07	182	239	9	e67f3234165199085c793915ebb1f9bbd845e933
ToppCell	E18.5-samps-Endothelial-Mature_fetal_endothelial-endothelial_cells_A\|E18.5-samps / Age Group, Lineage, Cell class and subclass	ERG DLGAP5 DACH1 CDCA2 ADGRF5 PARPBP CCNB1 IDO2 ARAP3	6.45e-07	182	239	9	ea4f6c8f600ffe9f8e0609637b3371a5ac48ca03
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK4 ERG ENPP2 DLC1 ADGRF5 PLCL1 PREX2 ARAP3 PDLIM1	6.75e-07	183	239	9	dc19857b66dcadbf7c87de91f7b1f4e8ef2857ed
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK4 ERG ENPP2 DLC1 ADGRF5 PLCL1 PREX2 ARAP3 PDLIM1	6.75e-07	183	239	9	4759560e5b4f4e5a00e5f933e3451a27c7c4aefe
ToppCell	COVID-19-Fibroblasts-Pericytes\|COVID-19 / group, cell type (main and fine annotations)	PDE3A DACH1 EBF2 DLC1 ADGRF5 LRCH2 PREX2 EDNRB GUCY1A2	7.39e-07	185	239	9	4905adaeeffd353e089578e5ea614437dbe794e6
ToppCell	COVID-19-Endothelial_cells-Systemic_venous_endothelial_cells\|COVID-19 / group, cell type (main and fine annotations)	ERG ENPP2 DACH1 SELP CLIC4 CACHD1 PREX2 PDLIM1 PDE7B	7.39e-07	185	239	9	f5e14181f45c37d13ee9e017a4c8bc248c353676
ToppCell	Primary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1-6_FGFR3_ETNPPL\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PTGDS HEPH NFATC4 AHNAK PHYHD1 CACHD1 TFAP2C PREX2 ATP1A2	7.73e-07	186	239	9	73cf266aeecd3cc15e8cb6094588a393bca8fbe6
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ABCA13 ARHGEF38 ITGA3 MYO5C NAV2 ADGRF5 NR3C2 CACHD1 SLC4A4	7.73e-07	186	239	9	acfa68a2afb7d2b51c9b469a1965fe5cc5d5e64e
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Astro-Astrocyte\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PTGDS HEPH NFATC4 AHNAK PHYHD1 PREX2 EDNRB ATP1A2 SLC4A4	8.09e-07	187	239	9	dd1d91f101b837bba513f77defa6e6902b2c0570
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Astro-Astrocyte\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PTGDS HEPH SRPX2 NFATC4 AHNAK PHYHD1 PREX2 EDNRB ATP1A2	8.09e-07	187	239	9	5c73010fe4c85fb5cc1273f5504821229ca0cc4b
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Astro\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PTGDS HEPH NFATC4 AHNAK PHYHD1 PREX2 EDNRB ATP1A2 SLC4A4	8.09e-07	187	239	9	ae90c263f80c36a410150d499e268d198944a3d9
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Astro\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PTGDS HEPH SRPX2 NFATC4 AHNAK PHYHD1 PREX2 EDNRB ATP1A2	8.09e-07	187	239	9	5d3d68519c8e19f10c29f9d81712125be78ca15a
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ARHGEF38 LGR4 RNF150 NAV2 NR3C2 PLCL1 USP53 RALGPS1 LRBA	8.84e-07	189	239	9	f51cdc9a47371cab8ed9ae63a6f14da07ede446c
ToppCell	PND07-28-samps-Mesenchymal-Matrix_fibroblast\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	STARD13 DOCK4 DLC1 UPK1B NAV2 CNN2 PREX2 MACF1 ATP1A2	8.84e-07	189	239	9	dc5164591dea45b420798b94dda211be03daa70c
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	DAPK1 ITGA3 MYO5C DLC1 PKHD1 NR3C2 CACHD1 MYH14 LRBA	9.23e-07	190	239	9	8aea807a2bcf0b653b4de6202b6ecb0f0683cc2e
ToppCell	Children_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ERG DACH1 ITGA3 ADGRF5 CLIC4 PREX2 EDNRB NMD3 ARAP3	9.23e-07	190	239	9	0a351609a72fd638c84b2435782e312ee6a33aac
ToppCell	Primary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Astro-Astrocyte\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PTGDS HEPH NFATC4 AHNAK PHYHD1 CACHD1 TFAP2C PREX2 ATP1A2	9.23e-07	190	239	9	e67d9400467b438592690b23d681e6c2fb8f09fd
ToppCell	Primary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Astro\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PTGDS HEPH NFATC4 AHNAK PHYHD1 CACHD1 TFAP2C PREX2 ATP1A2	9.23e-07	190	239	9	78cc6c28b31de041c24175a98f47da256ecc15a2
ToppCell	COVID-19-Heart-EC_3\|Heart / Disease (COVID-19 only), tissue and cell type	DOCK4 ERG LYST MYO5C SULF2 SELP CACHD1 PREX2 ARAP3	9.23e-07	190	239	9	78e7c502b0450c0b37652b1896a2a752fd8a2111
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	DAPK1 ITGA3 MYO5C DLC1 PKHD1 NAV2 ADGRF5 NR3C2 CACHD1	9.65e-07	191	239	9	ca5669bd6f4a17471acae3eb229f845cc2e08efa
ToppCell	Epithelial\|World / Lineage, Cell type, age group and donor	ARHGEF38 ITGA3 MYO5C DLC1 NAV2 ADGRF5 NR3C2 CACHD1 MYH14	1.01e-06	192	239	9	499e8893afea5e6d3371e0bd018f7e86a524d669
ToppCell	renal_cortex_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	DACH1 PKHD1 PLCL1 AHCYL2 ZSWIM6 MACF1 SSH2 LRBA SLC4A4	1.01e-06	192	239	9	e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCell	RV-10._Endothelium_II\|World / Chamber and Cluster_Paper	DOCK4 ERG DAPK1 SULF2 ADGRF5 SELP CHSY1 ARAP3 PDE7B	1.05e-06	193	239	9	2531266bc57339d4e2b22a88817008e32b8c1598
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_adventitial_fibro_(10)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	PDE3A CSMD3 EBF2 SULF2 AHNAK PLCL1 MN1 LGALS1 PAPPA	1.05e-06	193	239	9	cd45118ced91b10baed3b1068d4673ec99824b86
ToppCell	Fetal_29-31_weeks-Epithelial\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ARHGEF38 DAPK1 ITGA3 MYO5C PKHD1 NAV2 ADGRF5 NR3C2 MYH14	1.05e-06	193	239	9	a0ca3231992f14abcf1a6129573bace320e89d2a
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PDE3A HEPH SRPX2 TRANK1 DLC1 NFATC4 NAV2 EDNRB GUCY1A2	1.10e-06	194	239	9	81713e0409e8be695ba5dfdc67a997b33435dd9e
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_adventitial_fibro_(9)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	PDE3A CES1 DAPK1 CSMD3 USP53 PREX2 LGALS1 EDNRB PDE5A	1.10e-06	194	239	9	5f5f0cdeacd5e1b28717d78dabdb9eb95f661e36
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PDE3A HEPH SRPX2 TRANK1 DLC1 NFATC4 NAV2 EDNRB GUCY1A2	1.10e-06	194	239	9	627cffe2d448e74fc5df92e74e5b922a73304137
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-SMC_prolif-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	PDE3A ITGAV EBF2 NFATC4 ADGRF5 SPATS2L GUCY1A2 PDLIM1 PDE5A	1.10e-06	194	239	9	78dcb9d48259afabe73b41c5508a73a8d62339a4
ToppCell	Bronchial-NucSeq-Endothelial-Endothelia_vascular-VE_systemic_venous\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ERG SULF2 HOXD3 SELP CHSY1 PREX2 ARAP3 PDLIM1 PDE7B	1.15e-06	195	239	9	fde8e7b38b3631109b95ef111c5f6e3f9878cfbd
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK4 ERG DLC1 SSH1 SELP CLIC4 PREX2 ARAP3 PDLIM1	1.15e-06	195	239	9	818bc18c5834238e5f733cac6fe928ed0788f57d
ToppCell	nucseq-Epithelial\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ARHGEF38 ITGA3 MYO5C DLC1 ATF7IP2 NAV2 ADGRF5 MYH14 LRBA	1.15e-06	195	239	9	9406866f99555198a9be311fbd65751b70f35446
ToppCell	COVID-19-kidney-TAL\|kidney / Disease (COVID-19 only), tissue and cell type	ARHGEF38 LGR4 DAPK1 ITGA3 MYO5C DST PKHD1 NAV2 NR3C2	1.20e-06	196	239	9	04f5eb206ed3016a737609a3ebac0c1fcabb94ef
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK4 ERG DLC1 ADGRF5 SELP CLIC4 PREX2 ARAP3 PDLIM1	1.20e-06	196	239	9	d37f714d4fb57e958f3738fdda085560813e5bb5
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c10-MKI67-GZMK\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	DLGAP5 MCM7 GTF3C3 CDCA2 INTS14 POP1 ANKMY2 CCNB1 EIF2B1	1.20e-06	196	239	9	de70cc301a8cbaedb0a5ea4a6442dcdaa477822d
ToppCell	Striatum-Macroglia-POLYDENDROCYTE-P5-P5_1-Sox4-POLYDENDROCYTE_(Rostral-�migratory_stream-�(RMS)_(Tuba1c))\|Striatum / BrainAtlas - Mouse McCarroll V32	MIS18BP1 DLGAP5 CDCA2 PARPBP SPAG5 CCNB1 LRRN4	1.23e-06	101	239	7	0b32e6071f05dbe808e51e18c3a3f8221f438f83
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ERG RNF150 SRPX2 DLC1 NFATC4 NAV2 PREX2 EDNRB GUCY1A2	1.25e-06	197	239	9	85a8f1d18e0dd1d31341f5131eecd217553bf042
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ERG RNF150 SRPX2 DLC1 NFATC4 NAV2 PREX2 EDNRB GUCY1A2	1.25e-06	197	239	9	e8e3ba791dfaa0fab35e0329a5e34376f9ee6143
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	ENPP2 DACH1 DAPK1 PTGDS CSMD3 SRPX2 DLC1 DST MACF1	1.25e-06	197	239	9	0034bae02ee7fcfea520d453ca3c842ab6963b12
ToppCell	5'-GW_trimst-1-SmallIntestine-Mesenchymal-immature_mesenchymal_cell-cycling_stromal\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MIS18BP1 DLGAP5 CDCA2 NAV2 PARPBP LGALS1 SPAG5 CCNB1 DDX39A	1.30e-06	198	239	9	c3dd887c95587f930b7afd32385627a9fa029ca4
ToppCell	Control_saline\|World / Treatment groups by lineage, cell group, cell type	ERG SPEF2 DACH1 MPDZ DST AHNAK ADGRF5 ARAP3 MACF1	1.36e-06	199	239	9	11c9c1779caceb725ecccf3f23b7d4e6dbd1af64
ToppCell	343B-Fibroblasts-Fibroblast-G\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	DOCK4 CES1 ENPP2 PTGDS DST CNN2 USP53 MACF1 PRG4	1.36e-06	199	239	9	212e89d097753790061310373a1fafba773488b6
ToppCell	343B-Fibroblasts-Fibroblast-G-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	DOCK4 CES1 ENPP2 PTGDS DST CNN2 USP53 MACF1 PRG4	1.36e-06	199	239	9	14b676aa289c0578a37be32cec3ea285c79d97cc
ToppCell	Tracheal-10x5prime-Endothelial-Endothelia_vascular-VE_pulmonary_arterial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	STARD13 PDE3A ERG DACH1 ADGRF5 SELP CHSY1 PREX2 ARAP3	1.36e-06	199	239	9	9735a1dc10910f02f1106b20ae5ab4c09c21305e
ToppCell	ASK452-Endothelial\|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq	STARD13 ERG ENPP2 DLC1 SSH1 ADGRF5 SELP PREX2 PDLIM1	1.36e-06	199	239	9	0bc97a9a78aaafd1554ae6a61356ed9ea4983fa5
ToppCell	Hematolymphoid-Endothelial-NOSTRIN\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	ERG MPDZ SRPX2 DLC1 AHNAK ADGRF5 CLIC4 PREX2 ATP1A2	1.41e-06	200	239	9	032df80aa5c40991e1c1e80f9d8da106e6aeaee2
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Activated_Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	GBP6 ERG ENPP2 GBP3 DLC1 SPTLC2 PREX2 PDLIM1 MACF1	1.41e-06	200	239	9	2d07237022b409c4fac6fcf99b68c8affb3007cd
ToppCell	Hematolymphoid-Endothelial-NOSTRIN---\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	ERG MPDZ SRPX2 DLC1 AHNAK ADGRF5 CLIC4 PREX2 ATP1A2	1.41e-06	200	239	9	68fce28690246895fd33354b30960ebcc31aa4cc
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Activated_Alv_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	GBP6 ERG DACH1 GBP3 DST AHNAK ADGRF5 EDNRB MACF1	1.41e-06	200	239	9	79e51afb57ca38aacebd0298e5e727b55c0cfff9
ToppCell	Hematolymphoid-Endothelial-NOSTRIN----L2-6\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	ERG MPDZ SRPX2 DLC1 AHNAK ADGRF5 CLIC4 PREX2 ATP1A2	1.41e-06	200	239	9	878bbbe32e3602723aa14ef32877ab2453b8c6e5
ToppCell	Tracheal-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DACH1 HEPH DLC1 NFATC4 NAV2 PLCL1 PREX2 CORIN PAPPA	1.41e-06	200	239	9	58b38f9a484ee94191091a0659ed62ebed2d4a14
ToppCell	Hematolymphoid-Endothelial-NOSTRIN-\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	ERG MPDZ SRPX2 DLC1 AHNAK ADGRF5 CLIC4 PREX2 ATP1A2	1.41e-06	200	239	9	376b19ab5a7cd2c85f726d8ba41337d4525863e5
ToppCell	Hematolymphoid-Endothelial-NOSTRIN--\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	ERG MPDZ SRPX2 DLC1 AHNAK ADGRF5 CLIC4 PREX2 ATP1A2	1.41e-06	200	239	9	7fa54370221ed61bac0e09e6bcf1f3dff202a846
ToppCell	Hematolymphoid-Endothelial\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	ERG MPDZ SRPX2 DLC1 AHNAK ADGRF5 CLIC4 PREX2 ATP1A2	1.41e-06	200	239	9	7136936d05ab344a560cf159684c881063b5430d
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Akr1c18_Ntf3\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	DACH1 FRMPD1 CLIC4 LGALS1 MYH14 SP9 CORIN PDE5A	1.47e-06	149	239	8	1e77f03d2b32f366018fec3462d1b75f6e7febb9
ToppCell	PND28-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_prolif\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DLGAP5 MCM7 DOCK5 MED24 HAUS4 USP30 LGALS1 KLRK1	2.51e-06	160	239	8	5cc1b75e3c20d83112b3aa2f3c749a6c73910a2d
ToppCell	368C-Myeloid-Dendritic-cDC1\|Dendritic / Donor, Lineage, Cell class and subclass (all cells)	TIGD7 SIGLEC10 DHX57 CCNJ KLRK1 VAC14 PADI6 SLX4	2.89e-06	163	239	8	299ac2463b7f58eee419d822a2a2d64b973d87e9
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Reln_Tac1\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	DOCK4 SRPX2 FRMPD1 CLIC4 LGALS1 SP9 PDE5A SLC4A4	3.16e-06	165	239	8	d8df50f5a3b646e8ea13739fdc65ce6f39b4d4d2
ToppCell	Control\|World / group, cell type (main and fine annotations)	MYO5C DLC1 NAV2 ADGRF5 NR3C2 MYH14 SLC4A4 MUC5AC	3.61e-06	168	239	8	a3511faf2cd2c2b9c8363c8b99da3f3609c43ed6
ToppCell	Control-Epithelial_cells-ECM-high_epithelial\|Control / group, cell type (main and fine annotations)	DOCK4 MYO5C DLC1 DST ATF7IP2 NAV2 ADGRF5 MYO16	3.94e-06	170	239	8	e2023d66e70983c87dacbd6181d3426488d1fc57
ToppCell	390C-Myeloid-Macrophage-SPP1+_Macrophage_4\|390C / Donor, Lineage, Cell class and subclass (all cells)	LGR4 DAPK1 SIGLEC10 TRIM72 SLITRK4 FRMPD1 KCNK13 WDR19	3.94e-06	170	239	8	439167e44a1bd5ac8e1e457351dd202ec968db46
Drug	Chloroprene	DOCK4 GBP6 SAMD9 ERG DACH1 GBP3 DAPK1 LYST HNRNPL DOCK5 DLC1 NAV2 ALAS1 FLRT3 CXCL5 MN1 FGFBP1 SZT2 CLIC4 TEX11 PREX2 DENND4C EDNRB SPAG5 CCNB1 KLRK1 HIPK3 STYXL1 PDE5A FAM53B LRRC8B LRRN4 SLC4A4 PDE7B	1.29e-06	1348	235	34	ctd:D002737
Drug	N(6)-methyl-2'-deoxyadenosine 3',5'-diphosphate	ITGA2B ITGB3 SELP	4.31e-06	4	235	3	ctd:C111914
Drug	Vanadates	DOCK4 SYNRG USP9X ENPP2 LGR4 ITGB3 MYO5C MED24 SRPX2 MPP4 SYDE2 ATF7IP2 MAP7D2 AKT1 NR3C2 CPLANE1 ZNF844 CXCL5 WDR17 GNPTAB CACHD1 ZSWIM6 ADAM32 TFAP2C SPAG5 CCNB1 NMD3 RALGPS1 PAPPA LRRC8B SLC4A4 PDE7B	4.71e-06	1302	235	32	ctd:D014638
Disease	respiratory symptom change measurement, response to placebo	EBF2 CDCA2 ATF7IP2 NAV2	7.90e-06	17	230	4	EFO_0008344, EFO_0010068
Disease	Astigmatism	DOCK4 ABCA13 MPDZ PLCL1 USP53 CHSY1 WDR27 THSD7B	8.18e-06	129	230	8	HP_0000483
Disease	Primary Ciliary Dyskinesia	SPAG1 SPEF2 DNAH1 GAS2L2 IFT122	3.24e-05	47	230	5	C4551720
Disease	FEV/FEC ratio	STARD13 PDE3A DIPK1A SPEF2 MRPL30 ARHGEF38 MCM7 ITGAV HAUS4 DLC1 DST HOXD3 NAV2 PLCL1 HERC1 MN1 PML NSD1 TFAP2C ERGIC1 SPATS2L SSH2 PRG4 MYO16	3.61e-05	1228	230	24	EFO_0004713
Disease	platelet-type bleeding disorder 16 (implicated_via_orthology)	ITGA2B ITGB3	6.05e-05	2	230	2	DOID:0060691 (implicated_via_orthology)
Disease	Glanzmann Thrombasthenia, Type A	ITGA2B ITGB3	6.05e-05	2	230	2	C3179396
Disease	platelet-type bleeding disorder 16 (is_implicated_in)	ITGA2B ITGB3	6.05e-05	2	230	2	DOID:0060691 (is_implicated_in)
Disease	Glanzmann Thrombasthenia, Autosomal Dominant	ITGA2B ITGB3	6.05e-05	2	230	2	C1861195
Disease	platelet-type bleeding disorder 16 (is_marker_for)	ITGA2B ITGB3	6.05e-05	2	230	2	DOID:0060691 (is_marker_for)
Disease	Thrombasthenia	ITGA2B ITGB3	6.05e-05	2	230	2	C0040015
Disease	susceptibility to common cold measurement	SPEF2 ARHGEF38 DOCK5 RALGPS1 MYO16	6.38e-05	54	230	5	EFO_0008417
Disease	Kartagener Syndrome	SPAG1 SPEF2 DNAH1 GAS2L2	1.56e-04	35	230	4	C0022521
Disease	Ciliary Dyskinesia, Primary, 1, With Or Without Situs Inversus	SPAG1 SPEF2 DNAH1 GAS2L2	1.56e-04	35	230	4	C4551906
Disease	Polynesian Bronchiectasis	SPAG1 SPEF2 DNAH1 GAS2L2	1.56e-04	35	230	4	C4317124
Disease	ATRIAL SEPTAL DEFECT 1	MYT1L TRIP12	1.81e-04	3	230	2	C1862389
Disease	Glanzmann's thrombasthenia (is_implicated_in)	ITGA2B ITGB3	1.81e-04	3	230	2	DOID:2219 (is_implicated_in)
Disease	autosomal recessive polycystic kidney disease (implicated_via_orthology)	PKD1 PKHD1 AKT1	2.43e-04	16	230	3	DOID:0110861 (implicated_via_orthology)
Disease	Internal Carotid Artery Thrombosis	ITGA2B ITGB3	3.59e-04	4	230	2	C0750990
Disease	Common Carotid Artery Thrombosis	ITGA2B ITGB3	3.59e-04	4	230	2	C0750988
Disease	External Carotid Artery Thrombosis	ITGA2B ITGB3	3.59e-04	4	230	2	C0750989
Disease	Cranioectodermal dysplasia	WDR19 IFT122	3.59e-04	4	230	2	cv:C4551571
Disease	Carotid Artery Thrombosis	ITGA2B ITGB3	3.59e-04	4	230	2	C0007274
Disease	gonadal dysgenesis (implicated_via_orthology)	STARD13 DLC1	3.59e-04	4	230	2	DOID:14447 (implicated_via_orthology)
Disease	apolipoprotein A 1 measurement	PDE3A CES1 MED24 SULF2 TRANK1 DLC1 ZPR1 PLA2G6 AKT1 HERC1 NSD1 CLIC4 NR1H3 AIP DDX55 MACF1 FAM53B	3.85e-04	848	230	17	EFO_0004614
Disease	Colorectal Carcinoma	ABCA13 CSMD3 STK11 KMT2C DLC1 PKHD1 AKT1 NR3C2 ANAPC4 PREX2 ARHGEF10L GMCL2 ARAP3 GUCY1A2 MUTYH	4.41e-04	702	230	15	C0009402
Disease	neutrophil count	ERG DIPK1A MED24 GLG1 PKD1 AKT1 ADGRF5 PLCL1 UBE2Z CNN2 SELP USP53 NSD1 CHSY1 WDR27 PREX2 PDLIM1 STYXL1 FAM53B SSH2 LRBA SLC4A4 MAP2K5	5.38e-04	1382	230	23	EFO_0004833
Disease	body surface area	ENPP2 TRIP12 ITGB3 DOCK5 DLC1 PKHD1 PLA2G6 ZNF844 NSD1 CHSY1 HSD17B12 MACF1 PAPPA MAP2K5	5.67e-04	643	230	14	EFO_0022196
Disease	Atrial Septal Defects	MYT1L TRIP12	5.96e-04	5	230	2	C0018817
Disease	CRANIOECTODERMAL DYSPLASIA 1	WDR19 IFT122	5.96e-04	5	230	2	C0432235
Disease	Klatskin's tumor (is_implicated_in)	KMT2C PREX2	5.96e-04	5	230	2	DOID:4927 (is_implicated_in)
Disease	Acute Cerebrovascular Accidents	PDE3A ITGA2B ITGAV ITGB3	8.38e-04	54	230	4	C0751956
Disease	Neoplasms, Therapy-Associated	DAPK1 PML	8.89e-04	6	230	2	C0086696
Disease	glucagon measurement, glucose tolerance test	HERC1 MACF1	8.89e-04	6	230	2	EFO_0004307, EFO_0008463
Disease	Neonatal Alloimmune Thrombocytopenia	ITGA2B ITGB3	8.89e-04	6	230	2	C3853779
Disease	FNAITP	ITGA2B ITGB3	8.89e-04	6	230	2	C3854603
Disease	Neoplasms, Second Primary	DAPK1 PML	8.89e-04	6	230	2	C0085183
Disease	Treatment related secondary malignancy	DAPK1 PML	8.89e-04	6	230	2	C0877578
Disease	Adenocarcinoma of large intestine	TRRAP DLC1 AKT1 AKT2 MUTYH	9.47e-04	96	230	5	C1319315
Disease	uterine fibroid	MCM8 EBF2 CDCA2 DOCK5 DMRT1 SLITRK4 TEX11	9.94e-04	199	230	7	EFO_0000731
Disease	HVA measurement	ERG KIF13B DENND4C	1.06e-03	26	230	3	EFO_0005131
Disease	mean platelet volume	DLGAP5 ITGA2B ITGB3 DOCK5 SRPX2 TRANK1 SSH1 ZPR1 ADGRF5 NR3C2 DDX39B CNN2 CLIC4 GMCL2 PDLIM1 STYXL1 FAM53B PADI6	1.14e-03	1020	230	18	EFO_0004584
Disease	Malignant neoplasm of testis	STK11 DMRT1	1.24e-03	7	230	2	C0153594
Disease	Autosomal dominant macrothrombocytopenia	ITGA2B ITGB3	1.24e-03	7	230	2	C4304021
Disease	Cerebral Hemorrhage	ITGA2B ITGAV ITGB3	1.33e-03	28	230	3	C2937358
Disease	Cerebrovascular accident	PDE3A ITGA2B ITGAV ITGB3	1.41e-03	62	230	4	C0038454
Disease	Neoplasm of uncertain or unknown behavior of ovary	STK11 AKT1 AKT2	1.47e-03	29	230	3	C0496920
Disease	Alzheimer disease, age at onset	DACH1 CSMD3 DST AHNAK NR3C2 SZT2 HSD17B12 KDM1B MYO16	1.57e-03	343	230	9	EFO_0004847, MONDO_0004975
Disease	Ovarian Carcinoma	STK11 AKT1 AKT2	1.62e-03	30	230	3	C0029925
Disease	Subarachnoid Hemorrhage, Aneurysmal	UNC5B EDNRB	1.64e-03	8	230	2	C0751530
Disease	Subarachnoid Hemorrhage, Spontaneous	UNC5B EDNRB	1.64e-03	8	230	2	C0472383
Disease	Testicular Neoplasms	STK11 DMRT1	1.64e-03	8	230	2	C0039590
Disease	Subarachnoid Hemorrhage, Intracranial	UNC5B EDNRB	1.64e-03	8	230	2	C0795688
Disease	Perinatal Subarachnoid Hemorrhage	UNC5B EDNRB	1.64e-03	8	230	2	C0270192
Disease	eye morphology measurement	MYT1L NR3C2 CNN2 WDR27 GUCY1A2 PAPPA PDE7B	1.68e-03	218	230	7	EFO_0007858
Disease	Subarachnoid Hemorrhage	UNC5B EDNRB	2.10e-03	9	230	2	C0038525
Disease	lifestyle measurement, systolic blood pressure	EBF2 CDCA2	2.10e-03	9	230	2	EFO_0006335, EFO_0010724
Disease	cup-to-disc ratio measurement	DAPK1 GLG1 NAV2 PLA2G6 MN1 CHSY1 ZSWIM6 LGALS1 ERGIC1 MYO16	2.14e-03	430	230	10	EFO_0006939
Disease	Leukemia, Myelocytic, Acute	ERG DAPK1 KMT2C MN1 NSD1 SLX4	2.43e-03	173	230	6	C0023467
Disease	age at menarche	SULF2 DST PLCL1 ANAPC4 PML EFL1 THSD7B VAC14 HSD17B12 MAP2K5 PDE7B SLX4	2.58e-03	594	230	12	EFO_0004703
Disease	premature ejaculation	SULF2 FAM53B	2.61e-03	10	230	2	EFO_0803321
Disease	Acute Myeloid Leukemia, M1	ERG DAPK1 KMT2C MN1 NSD1	3.03e-03	125	230	5	C0026998
Disease	Acute Myeloid Leukemia (AML-M2)	ERG DAPK1 KMT2C MN1 NSD1	3.03e-03	125	230	5	C1879321
Disease	neutropenia, response to gemcitabine	DLC1 UPK1B	3.18e-03	11	230	2	GO_0036272, MONDO_0001475
Disease	response to risperidone	DOCK5 ATF7IP2 HMGXB3	3.22e-03	38	230	3	GO_0097336
Disease	Malignant Neoplasms	BIRC6 STK11 DLC1 AKT1 AKT2	3.35e-03	128	230	5	C0006826
Disease	Dental enamel hypoplasia	MYH14 SLC4A4	3.79e-03	12	230	2	EFO_1001304
Disease	Hirschsprung's disease (implicated_via_orthology)	MED24 EDNRB	3.79e-03	12	230	2	DOID:10487 (implicated_via_orthology)
Disease	Global developmental delay	TRRAP GTF3C3 MN1 SZT2 NBAS	3.95e-03	133	230	5	C0557874
Disease	Cutaneous Melanoma	TRRAP STK11 AKT1	4.01e-03	41	230	3	C0151779
Disease	progression free survival, response to carboplatin, methylcobalamin deficiency type cblE, ovarian serous carcinoma	ERG DAPK1 MN1	4.29e-03	42	230	3	EFO_0004920, EFO_1001516, GO_0097328, MONDO_0009354
Disease	alcohol use disorder (implicated_via_orthology)	SSH1 AKT1 AKT2 CLIC4 SSH2 ATP1A2	4.38e-03	195	230	6	DOID:1574 (implicated_via_orthology)
Disease	Autism Spectrum Disorders	MYT1L TRIP12 ITGB3 CHD8	4.45e-03	85	230	4	C1510586
Disease	myeloid leukemia (is_implicated_in)	ERG MN1	4.46e-03	13	230	2	DOID:8692 (is_implicated_in)
Disease	Benign tumor of pancreas	STK11 AKT2	4.46e-03	13	230	2	C0347284
Disease	putamen volume change measurement	SYDE2 MYO16	4.46e-03	13	230	2	EFO_0021495
Disease	methylcobalamin deficiency type cblE, response to antineoplastic agent	ERGIC1 LRRC8B	4.46e-03	13	230	2	GO_0097327, MONDO_0009354
Disease	rhinitis (biomarker_via_orthology)	OPA1 MUC5AC	4.46e-03	13	230	2	DOID:4483 (biomarker_via_orthology)
Disease	intermediate coronary syndrome (is_marker_for)	AKT1 SELP	4.46e-03	13	230	2	DOID:8805 (is_marker_for)
Disease	neuroimaging measurement	SAMD9 ENPP2 SULF2 PKD1 PKHD1 NAV2 PLCL1 DMRT1 UBE2Z SZT2 DENND4C RALGPS1 MACF1 PAPPA FAM53B SSH2 MYO16	4.49e-03	1069	230	17	EFO_0004346
Disease	smoking status measurement	MYT1L MON2 SAMD9 DACH1 BIRC6 EBF2 RNF150 DLC1 PKHD1 NAV2 PLCL1 HERC1 WDR27 THSD7B ATP2C1 SPATS2L HSD17B12 MAP2K5	4.50e-03	1160	230	18	EFO_0006527
Disease	fertility measurement	NAV2 NBAS	5.18e-03	14	230	2	EFO_0006923
Disease	cancer (implicated_via_orthology)	ITGA3 TRIP12 ITGB3 DST AKT1 AKT2 MACF1	5.24e-03	268	230	7	DOID:162 (implicated_via_orthology)
Disease	hypertrophic cardiomyopathy	KMT2C AHNAK PKD1 ZNF592	5.88e-03	92	230	4	EFO_0000538
Disease	caudate nucleus measurement, functional brain measurement, response to reward	CSMD3 FAM135B MYO16	5.89e-03	47	230	3	EFO_0007849, EFO_0008387, EFO_0008396
Disease	ovarian carcinoma (is_implicated_in)	STK11 AKT2	5.94e-03	15	230	2	DOID:4001 (is_implicated_in)
Disease	glucose homeostasis measurement, glucose effectiveness measurement	MYO5C MYH14	5.94e-03	15	230	2	EFO_0006833, EFO_0006896
Disease	impotence (implicated_via_orthology)	AKT1 PDE5A	5.94e-03	15	230	2	DOID:1875 (implicated_via_orthology)
Disease	attention function measurement	PDE3A DST CLIC4 RALGPS1 LRBA	6.19e-03	148	230	5	EFO_0007636
Disease	photoreceptor cell layer thickness measurement	IMPG1 DST PLCL1 MN1 IFT122	6.19e-03	148	230	5	EFO_0803370
Disease	hippocampal CA1 volume	CHSY1 PAPPA FAM53B	6.24e-03	48	230	3	EFO_0009394
Disease	Myocardial Infarction	PDE3A ITGB3 NR3C2 PAPPA	6.58e-03	95	230	4	C0027051
Disease	vitamin D measurement, COVID-19	ZPR1 SEC23A SLC4A4	6.61e-03	49	230	3	EFO_0004631, MONDO_0100096
Disease	triacylglycerol 50:5 measurement	DACH1 ZPR1	6.76e-03	16	230	2	EFO_0010412
Disease	Polyposis, Adenomatous Intestinal	AKT1 MUTYH	6.76e-03	16	230	2	C2713442
Disease	Familial Intestinal Polyposis	AKT1 MUTYH	6.76e-03	16	230	2	C2713443
Disease	waist circumference	MRPL30 RNF150 PKHD1 NAV2 PLCL1 TEX11 ATP2C1 HSD17B12 MAP2K5	6.80e-03	429	230	9	EFO_0004342
Disease	response to fenofibrate	DOCK4 AHCYL2 FAM135B	7.00e-03	50	230	3	GO_1901557
Disease	disease recurrence, colon carcinoma	THSD7B GUCY1A2 MACF1	7.39e-03	51	230	3	EFO_0004952, EFO_1001950
Disease	Adenomatous Polyposis Coli	AKT1 MUTYH	7.62e-03	17	230	2	C0032580
Disease	ischemia (implicated_via_orthology)	ITGAV AKT2	7.62e-03	17	230	2	DOID:326 (implicated_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
PLNNFSVAQCQLMKT	AKT1	51	P31749
PLNNFSVAECQLMKT	AKT2	51	P31751
MCTQDPKAGQLLSEL	CES1	86	P23141
KDGNMPIVVALCEAN	DAPK1	586	P53355
NDMLVCANINFKPAN	ARHGEF10L	566	Q9HCE6
GNEMTLADCNLLPKL	CLIC4	181	Q9Y696
NNKAELNCLGMEPVQ	CHD8	2371	Q9HCK8
NCNAPKAVVLQTLAM	ERVK13-1	71	Q9NX77
CLQKPADVIGKSMNQ	ANAPC4	536	Q9UJX5
CAAVARPNLLKNMTQ	ARAP3	621	Q8WWN8
NLPCQKELVGAVMNP	TFAP2C	206	Q92754
QQCNKMPITADLVAP	BIRC6	3671	Q9NR09
ISCHPNNQKLMAQVL	BIRC6	3771	Q9NR09
LMQGPTKAQCQANRQ	CSMD3	2906	Q7Z407
KNLLVDPNSMNVSCL	CRYBG3	1286	Q68DQ2
NNVLQEKICAMEGLP	AFM	91	P43652
IPQAILGMDVLCQAK	DDX39B	76	Q13838
PQAILGMDVLCQAKS	DDX39A	76	O00148
NQKLQEKMTPQGECS	ARHGEF38	61	Q9NXL2
KNISLCLQHIQDAMP	ARHGEF38	361	Q9NXL2
GMKLLNQADPCVQIL	EFL1	636	Q7Z2Z2
IKMECNPSQVNGSRN	ERG	66	P11308
QSLPVKVNVRGLMCQ	FLRT3	321	Q9NZU0
PDMANQRKTALEFCG	FGFBP1	201	Q14512
ALQNLDGLVQMPSGC	A2ML1	956	A8K2U0
DSVPKLEQLNSLGCM	CCNJ	101	Q5T5M9
LMDLLPVCNQDGGNK	CACHD1	821	Q5VU97
EGQNKNPEMCRVLLT	EBF2	141	Q9HAK2
KQMLAKNAVCPNGRF	ABCA13	496	Q86UQ4
VMNLSGNCLRNLPEQ	IGFALS	366	P35858
NLQMPGIKSSGCDVN	AHNAK	5491	Q09666
GINMASLNSCINPIA	EDNRB	371	P24530
ISNVGVKCLQNKPQM	ADAM32	371	Q8TC27
RACVPLQMARQQGKQ	FAM186B	836	Q8IYM0
NTPQNNECKMVDLRG	DACH1	181	Q9UI36
CNDAVIRNNTLMGKP	ATP2C1	411	P98194
IACLKNLQMKEQPGS	AIP	206	O00170
LQLDGLIQQCGETMK	GMCL1	191	Q96IK5
MKQEPSCNNSPELQV	NSD1	126	Q96L73
ACKSNRPQVPANLMS	RALGPS1	541	Q5JS13
MQLIKGQNSRDPFCK	PARPBP	286	Q9NWS1
LGMIEKLVAAQQQCN	NR1H3	211	Q13133
NISALENCGSPAMKR	RAD9B	331	Q6WBX8
NTTLLKMADCGGLPQ	NDRG3	281	Q9UGV2
QMTLNVQGPSCILKK	PADI6	191	Q6TGC4
CSQDIMGPNILQNLK	PNLIPRP3	451	Q17RR3
MAAGQLCTELENKLP	KMT2C	3671	Q8NEZ4
INRCLNELGKTVPMA	HELT	26	A6NFD8
LSMQCLDIAQDPAQK	IFT122	921	Q9HBG6
PACRLQKCLQAGMNL	NR3C2	656	P08235
GIQCNEQSMPKSGLL	MAGEA11	301	P43364
NCIPIKNGSLLMVSD	MIS18BP1	291	Q6P0N0
NTLIGQMDCSLIPAN	MCMDC2	476	Q4G0Z9
MACGLVASNLNLKPG	LGALS1	1	P09382
LVVPNKMEINGLNTC	MAP7D2	581	Q96T17
PGLGKSQMLQAACNV	MCM8	456	Q9UJA3
NCSKMLPADITQLNN	GNPTAB	1056	Q3T906
NARKEAIKMCQQGAP	HSFX4	216	A0A1B0GTS1
SKCPFLAAQMNQRGS	ALAS1	106	P13196
LCKQQSQDSIPENPM	MYO16	371	Q9Y6X6
CPQESMKQILDSLQA	IMPG1	81	Q17R60
QQMLARCPKSAETNI	DST	6551	Q03001
LNCSTENMPIKINLI	EIF2S1	216	P05198
LKQQGVLGLNMAPCM	HERC1	3836	Q15751
CLPQTISNMKNLGTL	LRRC39	236	Q96DD0
NFLAINQKCPLQEMK	DDX55	381	Q8NHQ9
QAKFLPNCGDSTLAM	DCAF8L2	276	P0C7V8
QLELCVAQNQMSPKG	HMGXB3	146	Q12766
QLQAHVDKMPLLSCQ	IDO2	71	Q6ZQW0
GTNQMAVCAKAQNKP	EIF2B1	211	Q14232
QRPSLDLAKMAQNCQ	FAM53B	291	Q14153
MPDNTAAQKLCRLLG	MYH14	391	Q7Z406
KELPCINTPMQINGN	PLXNA3	371	P51805
GPDNKCESNLQMRAA	ITGA3	616	P26006
PSNMLVNTRGQVKLC	MAP2K5	286	Q13163
KNQGSLMPLQLLQCI	MAP2K5	361	Q13163
CNIVPKMAANFLSGR	OR2V1	76	Q8NHB1
VCQMCIKLADINGPA	PDE3A	941	Q14432
FDQCLMILNSPGNQI	PDE5A	686	O76074
AQNGLICNIMNAPAE	PDE6A	351	P16499
NPDQNAKCVCMLGDI	PDE7B	16	Q9NP56
PNLLTIIEMQKGDCA	KLRK1	176	P26718
IDNSMKIPLNNGAGC	ERGIC1	101	Q969X5
LLQMVKAPDSNCSNL	FAM234B	386	A2RU67
SNVLRVICNGKQPDM	GUCA1C	176	O95843
AMRIVCLVKNQQPLG	MPP4	151	Q96JB8
LKENGIPFNCMTQEA	KDM4E	251	B2RXH2
SNLQNGMPLLKQLCD	LRBA	556	P50851
ISSIPNNLCQEQKML	LGR4	331	Q9BXB1
MCLIENTNGELVANP	GBP3	11	Q9H0R5
KMLAPVCLVENNNEQ	GBP6	6	Q6ZN66
CNAKLLRNMPEFSGV	TUBGCP3	686	Q96CW5
AILQKQLSEMANGCP	KCNK13	361	Q9HB14
PQNLSSQPCIKMEGD	NLRP5	41	P59047
VCRNQDQQGPFKMCL	MUC5AC	2191	P98088
LVCRNQDQQGPFKMC	MUC5AC	3296	P98088
LVCRNQDQQGPFKMC	MUC5AC	4701	P98088
GQQALELPECTMQKA	HOXD3	6	P31249
VLQKAICVGPENMQI	MON2	1341	Q7Z3U7
HPAQLKGNNSLLTCM	PAPPA	1316	Q13219
NARKEAIKMCQQGAP	HSFX3	216	A0A1B0GWH4
MANTDSICQPLIKGR	HIPK3	1011	Q9H422
VAICLDGQPLAMIQQ	NBAS	2006	A2RRP1
NNNIEMLPDGLFQCK	LRRC8B	711	Q6P9F7
SAPGECHQIMKNLQA	MACF1	981	Q9UPN3
NICLMGDPGVAKSQL	MCM7	376	P33993
LFKISCNGPSINALM	OR5AC2	186	Q9NZP5
CPAGMLFAEEQAKNL	POP1	666	Q99575
MQNPNAIILCIQDGS	OPA1	426	O60313
IQEQGLQPTKANLMA	DNAH1	2686	Q9P2D7
LQCLKQNKNSELMDP	GLG1	901	Q92896
NIPMSQVNPREAKAC	ATP1A2	646	P50993
NNCVPKKMLQLVGVT	CCNB1	236	P14635
AQIVNGCINNPVALM	KDM1B	436	Q8NB78
QNINPLTMCLNGVID	DOCK4	1496	Q8N1I0
SIPDNQLVRQKLNCM	DOCK5	846	Q9H7D0
SCQNILNRMPTEAKN	CPLANE1	1851	Q9H799
SQGNSLLCMPNVLKL	FRMPD1	171	Q5SYB0
NMKLLEVRSACPQGT	GAS2L2	611	Q8NHY3
NAENPKLISAMLCAA	DHX57	1206	Q6P158
SKLLMICQNAGISVP	C3orf20	26	Q8ND61
FTIDGPLCLKNVQSM	INTS14	186	Q96SY0
CDLGNPMKAGTQLLA	ITGAV	711	P06756
NNCPAIMNALIEAGA	FEM1A	591	Q9BSK4
DMPCFLLSNQNAVKA	DLGAP5	126	Q15398
NILSVCKMTQLVLPG	HSD17B12	161	Q53GQ0
ANFSTLLMNLGPENC	DENND4C	391	Q5VZ89
NVRVNCLDENGMTPL	ANKMY2	36	Q8IV38
NGAQCPNEMLSKKAL	CEP95	196	Q96GE4
ILSQLACKQMGLGEP	CORIN	721	Q9Y5Q5
FQRNCLKPNMLSSNG	ATF7IP2	381	Q5U623
NTVAALNGLEKNIPM	LYST	2476	Q99698
ELHVNKPIAMNCSNL	SELP	706	P16109
GAAEGKLQCNRLMPN	CDCA2	771	Q69YH5
GQKLNVCVSKQPAIM	HNRNPL	446	P14866
LNNEVIPGLKSCMGL	ITGB3	401	P05106
LCSELQMLNNPEKIA	FAM135B	286	Q49AJ0
EGMEILQQVCSKQLP	HAUS4	11	Q9H6D7
MVAQDPQGCLQLCLS	HHIPL2	196	Q6UWX4
DNLPGVVKCQMEQAL	DIPK1A	106	Q5T7M9
TAMLQCLEAVEQNNP	RUBCN	166	Q92622
NVMCDLLGLKPAPNN	ENPP2	511	Q13822
KMISNLQVFAIGPQC	CXCL5	61	P42830
MACLSPSQLQKFQQD	PHYHD1	1	Q5SRE7
NNGKPLCSQLQHMSL	CPHXL	361	A0A1W2PPM1
LVKRENNGSNPCLMT	DMRT1	146	Q9Y5R6
CNEIQVLPQQMGKLH	LRCH2	211	Q5VUJ6
GDIFKMTPNLQQLDC	LRRN4	246	Q8WUT4
IQQIAAALAQCMGPS	PKD1	2661	P98161
QNGSMLKPAVCTREL	PARP6	296	Q2NL67
KVAASIGNAQKLPMC	PDLIM1	246	O00151
ACQNMIASLGAPNLN	MN1	831	Q10571
NILKALGIPPNADCM	RNF150	321	Q9ULK6
CENTNIMKNLPQGTS	GUCY1A2	296	P33402
ASLLQGQSQIRMCKP	MIDN	361	Q504T8
ANSQDIQLCGMGILP	KIF13B	476	Q9NQT8
NKMTCQNLAVCFGPV	SYDE2	971	Q5VT97
KQFALECSRIPMGQA	SZT2	3006	Q5T011
LGNPDCGSMQLQLRK	SLITRK4	656	Q8IW52
QLDPSLLTENGMKCF	USP9X	726	Q93008
ANVCNQSLMKLVTPE	VAC14	321	Q08AM6
DCILDGFPMTLNQAQ	SPEF2	721	Q9C093
ESFKAMQCIQIPNGD	STARD13	296	Q9Y3M8
LSKAGKLCVPAMNVN	AHCYL2	346	Q96HN2
EALAGQLDSNCQPMA	SPAG5	1091	Q96R06
AQIMLCGEITHPKNN	SPATS2L	346	Q9NUQ6
QGLPAEENMSNTCLK	MRPL30	126	Q8TCC3
SSCMLRPGIKNAQEL	SYNRG	1231	Q9UMZ2
NGCVDFMSKNVLPQR	TEDDM1	81	Q5T9Z0
LLPENNMAANIDCAG	NFATC4	511	Q14934
ANTLMAKALQECPNS	PRPF6	796	O94906
IILNCMRSQNPEKSA	SAMD9	831	Q5K651
KAQVQALGLAEAQPM	PML	426	P29590
LQLDGLIQQCGETMK	GMCL2	191	Q8NEA9
FGNLPELNMCAQKRV	HEPH	276	Q9BQS7
PAAGEKQLAMCLQRL	MED24	151	O75448
INGCPKNRSQMIENI	NAV2	136	Q8IVL1
KNQCETRTMLLQPAG	PTGDS	86	P41222
KNNSQAKPSACDGMI	MUTYH	41	Q9UIF7
LLVAQAACEGNMQPL	WDR17	906	Q8IZU2
QKRSEINLPGNCVAM	WDR19	46	Q8NEZ3
LGKVNQCPHQLMNGV	PKHD1	3936	P08F94
LQLLNAKPQECLMGT	IARS1	1176	P41252
LPKAVCMNGTEAAQL	STK11	386	Q15831
LTPLHLACQLGKQEM	PLA2G6	221	O60733
VLCELGNPMKKNAQI	ITGA2B	716	P08514
KENQMTPTNLAVCLA	DLC1	1216	Q96QB1
VPLVCNKSMFTQALN	URB1	431	O60287
NPMLSDETNICNGKP	PRG4	1136	Q92954
PLAMLAATCNKIGNT	SP9	16	P0CG40
ALDQTGLLEMKCCPN	SEC23A	351	Q15436
CAVKMEVGPQLLLQA	SLX4	356	Q8IY92
ENLNNNSKRSCPNGM	SSH1	616	Q8WYL5
KPNIMQSFNDPLLCG	SUPT20HL2	351	P0C7V6
MLKNPENHALCVLNG	GTF3C3	726	Q9Y5Q9
PNRLQKELSSMCPND	ACTL7A	371	Q9Y615
SMKLNLVPGENITCQ	ADGRF5	656	Q8IZF2
MGNFEKTCLIPNQNV	CHSY1	551	Q86X52
NSRPVIINMNLNKCD	C12orf29	281	Q8N999
QAEVAKMEPLNNVCA	CLCC1	241	Q96S66
DGTILCTLMNKLQPG	CNN2	56	Q99439
RSDGCQMPKLFCQNL	USP53	906	Q70EK8
LGNHCSLPQQKVMAQ	PLCL1	491	Q15111
VLPACGDLSFQQDQM	STK19	246	P49842
ECNAPAQTNMKLVQI	ZPR1	261	O75312
CVFNLTKQDLAAGMP	ZYG11B	386	Q9C0D3
RNKDAVNQMAVCPGN	MPDZ	1431	O75970
EQLAGPLRQMQECAK	MTREX	926	P42285
NNMCPNRGLVSQLLE	STYXL1	281	Q9Y6J8
MVPQDANQKGLCTKE	SSH2	511	Q76I76
TNSMNIPALVGKGCL	SPTLC2	241	O15270
PMKINVNVNSAAGLL	SRPX2	321	O60687
MQCSQLLVKPISADQ	ZNF592	646	Q92610
AAQPCVMGNIQKKLT	SPAG1	376	Q07617
KCMHNLVNLSVPDGA	TEX11	816	Q8IYF3
SCQMLPQGENLQDVL	TRABD2A	101	Q86V40
GLQEFQQEMEPKLSC	PREX2	1196	Q70Z35
NGDQGVLSICPLMNS	RFPL2	351	O75678
TQLPQQKLQLQEACM	TRIM72	131	Q6ZMU5
GLCMQNKKTLSDPNS	UNC5B	351	Q8IZJ1
CKDRLHLQGQTMQDP	UBE2Z	286	Q9H832
CVMNNLKEPLNLEAC	UPK1B	191	O75841
MGAQLCFEANAKAPR	NEURL3	1	Q96EH8
TLESNCMNLNNVKKP	ZNF844	526	Q08AG5
MAQQHPGLQKQDLCQ	TRIM17	86	Q9Y577
QCAMKDPQNCALSAL	ZSWIM6	986	Q9HCJ5
MNDCLPQNKVNISKA	ZMYM6	596	O95789
LVPGLVNLGNTCFMN	USP30	66	Q70CQ3
LVGNNCNFVPDITLM	SLC4A4	681	Q9Y6R1
AMAFGNKVNPLLICS	WDR27	76	A2RRH5
GQNAMLSLCLQDSFP	THSD7B	311	Q9C0I4
LKQTNGMPLLVQECT	THSD7B	851	Q9C0I4
AELALLMKCINDPNS	TRANK1	1401	O15050
MIQKENACNQPLDDI	SLC26A7	526	Q8TE54
PAKGNCSLVIRDAQM	SIGLEC10	96	Q96LC7
NCPTLAVQLMKQNIA	TRIP12	681	Q14669
GNAPLLALVHKMNNC	TRIP12	1211	Q14669
LIQPMNQGVILSCKR	TIGD7	326	Q6NT04
ELMNVPLQQQNKCTA	TCFL5	226	Q9UL49
KGMLQLLSNCPAETA	TRRAP	311	Q9Y4A5
AISINKGPKCLMANS	TM4SF4	111	P48230
LKRLQNNDTCSMPGL	SULF2	711	Q8IWU5
GRKMQPDQQVVINCA	VASP	51	P50552
LNSCQASQLGVRKMP	nan	81	Q9UFV3
AKQLRAENGLLMTPC	RPS6KA1	561	Q15418
LKSMCAGQRLASEPQ	MZT2A	76	Q6P582
LKSMCAGQRLASEPQ	MZT2B	76	Q6NZ67
TMCQNGLDPELVRQA	MYO5C	1561	Q9NQX4
MPQNLSTKPQDLCAT	MYT1L	746	Q9UL68
CLSPKLAQSLGNMNQ	NMD3	256	Q96D46