Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionprotein kinase activity

NTRK3 ROR1 RYK STK10 TNNI3K CSNK1D CSNK1E PAK1 PAK2 PAK3 NME2 MAP3K2

3.74e-056009812GO:0004672
GeneOntologyMolecularFunctiontransferase activity, transferring phosphorus-containing groups

NTRK3 POLR2A ROR1 NME2P1 ERVK-7 RYK STK10 TNNI3K CSNK1D CSNK1E PAK1 PAK2 PAK3 NME2 MAP3K2

5.08e-059389815GO:0016772
GeneOntologyMolecularFunctiontransmembrane receptor protein tyrosine phosphatase activity

PTPRU PTPRD PTPRF

7.42e-0517983GO:0005001
GeneOntologyMolecularFunctiontransmembrane receptor protein phosphatase activity

PTPRU PTPRD PTPRF

7.42e-0517983GO:0019198
GeneOntologyMolecularFunctionkinase activity

NTRK3 ROR1 NME2P1 RYK STK10 TNNI3K CSNK1D CSNK1E PAK1 PAK2 PAK3 NME2 MAP3K2

9.11e-057649813GO:0016301
GeneOntologyMolecularFunctionprotein tyrosine phosphatase activity

EPM2A PTPRU PTPRD PTPRF PTPRS

1.54e-04103985GO:0004725
GeneOntologyMolecularFunctionphosphotransferase activity, alcohol group as acceptor

NTRK3 ROR1 RYK STK10 TNNI3K CSNK1D CSNK1E PAK1 PAK2 PAK3 NME2 MAP3K2

1.82e-047099812GO:0016773
GeneOntologyMolecularFunctionexogenous lipid antigen binding

CD1A CD1E

2.36e-045982GO:0030884
GeneOntologyMolecularFunctionendogenous lipid antigen binding

CD1A CD1E

2.36e-045982GO:0030883
GeneOntologyMolecularFunctionphosphoprotein phosphatase activity

EPM2A PTPRU PTPRD PTPRF FIG4 PTPRS

3.40e-04189986GO:0004721
GeneOntologyMolecularFunctionprotein serine/threonine kinase activity

STK10 TNNI3K CSNK1D CSNK1E PAK1 PAK2 PAK3 NME2 MAP3K2

3.47e-04446989GO:0004674
GeneOntologyMolecularFunctionlipid antigen binding

CD1A CD1E

3.53e-046982GO:0030882
GeneOntologyMolecularFunctionchloride transmembrane transporter activity

SLC1A4 SLC6A11 CLCNKA CLCNKB MFSD8

3.78e-04125985GO:0015108
GeneOntologyMolecularFunctionprotein serine kinase activity

STK10 TNNI3K CSNK1D CSNK1E PAK1 PAK2 PAK3 MAP3K2

4.19e-04363988GO:0106310
GeneOntologyMolecularFunctionWnt-protein binding

TRABD2B ROR1 RYK

6.14e-0434983GO:0017147
GeneOntologyMolecularFunctionaspartic-type endopeptidase activity

ERVK-7 ERVK-18 ERVK-24

7.89e-0437983GO:0004190
GeneOntologyMolecularFunctionchloride channel activity

SLC1A4 CLCNKA CLCNKB MFSD8

8.51e-0486984GO:0005254
GeneOntologyMolecularFunctionaspartic-type peptidase activity

ERVK-7 ERVK-18 ERVK-24

8.54e-0438983GO:0070001
GeneOntologyMolecularFunctionmonoatomic anion transmembrane transporter activity

SLC1A4 SLC6A11 CLCNKA CLCNKB MFSD8

8.93e-04151985GO:0008509
GeneOntologyMolecularFunctionlipopeptide binding

CD1A CD1E

1.05e-0310982GO:0071723
GeneOntologyMolecularFunctionvoltage-gated chloride channel activity

CLCNKA CLCNKB

1.27e-0311982GO:0005247
GeneOntologyMolecularFunctionextracellular matrix structural constituent conferring tensile strength

COL4A3 COL4A5 COL4A6

1.49e-0346983GO:0030020
GeneOntologyMolecularFunctioninorganic anion transmembrane transporter activity

SLC1A4 SLC6A11 CLCNKA CLCNKB MFSD8

1.55e-03171985GO:0015103
GeneOntologyMolecularFunctionmonoatomic anion channel activity

SLC1A4 CLCNKA CLCNKB MFSD8

1.66e-03103984GO:0005253
GeneOntologyMolecularFunctionG-quadruplex DNA binding

LONP1 NME2

2.09e-0314982GO:0051880
GeneOntologyMolecularFunctionintermediate filament binding

EPPK1 NME2

2.40e-0315982GO:0019215
GeneOntologyMolecularFunctionphosphatase activity

EPM2A PTPRU PTPRD PTPRF FIG4 PTPRS

2.92e-03287986GO:0016791
GeneOntologyMolecularFunctionWnt receptor activity

ROR1 RYK

3.09e-0317982GO:0042813
GeneOntologyMolecularFunctionvoltage-gated monoatomic anion channel activity

CLCNKA CLCNKB

3.09e-0317982GO:0008308
GeneOntologyBiologicalProcessregulation of neuron projection development

MAG NTRK3 ROR1 HLA-E ADGRB3 RYK PTPRD PTPRF FIG4 PTPRS PAK1 PAK2 PAK3 NME2 CNTN2

1.93e-076129815GO:0010975
GeneOntologyBiologicalProcessregulation of plasma membrane bounded cell projection organization

MAG NTRK3 ROR1 HLA-E ADGRB3 SAXO1 RYK PTPRD PTPRF FIG4 PTPRS PAK1 PAK2 PAK3 NME2 CNTN2

2.26e-068469816GO:0120035
GeneOntologyBiologicalProcessregulation of cell projection organization

MAG NTRK3 ROR1 HLA-E ADGRB3 SAXO1 RYK PTPRD PTPRF FIG4 PTPRS PAK1 PAK2 PAK3 NME2 CNTN2

2.92e-068639816GO:0031344
GeneOntologyBiologicalProcesscell surface receptor protein tyrosine phosphatase signaling pathway

PTPRU PTPRD PTPRF

3.59e-067983GO:0007185
GeneOntologyBiologicalProcessregulation of axonogenesis

MAG NTRK3 RYK PTPRS PAK1 PAK2 PAK3 CNTN2

3.75e-06192988GO:0050770
GeneOntologyBiologicalProcesscell surface receptor protein tyrosine kinase signaling pathway

COL4A3 COL4A5 COL4A6 NTRK3 ROR1 RYK LONP1 PTPRF SULF1 ADGRE3 PAK1 PAK2 PAK3 MVB12B

1.15e-057479814GO:0007169
GeneOntologyBiologicalProcesspostsynaptic density assembly

NTRK3 PTPRD PTPRS LRRTM2

1.99e-0534984GO:0097107
GeneOntologyBiologicalProcesscollagen-activated tyrosine kinase receptor signaling pathway

COL4A3 COL4A5 COL4A6

2.22e-0512983GO:0038063
GeneOntologyBiologicalProcesspostsynaptic specialization assembly

NTRK3 PTPRD PTPRS LRRTM2

5.62e-0544984GO:0098698
GeneOntologyBiologicalProcessexcitatory synapse assembly

NTRK3 PTPRD PTPRS LRRTM2

6.71e-0546984GO:1904861
GeneOntologyBiologicalProcesscollagen-activated signaling pathway

COL4A3 COL4A5 COL4A6

8.06e-0518983GO:0038065
GeneOntologyBiologicalProcessregulation of postsynaptic density assembly

PTPRD PTPRS LRRTM2

1.30e-0421983GO:0099151
GeneOntologyBiologicalProcessregulation of axon extension

MAG NTRK3 RYK PTPRS PAK1

1.39e-04104985GO:0030516
GeneOntologyBiologicalProcessenzyme-linked receptor protein signaling pathway

COL4A3 COL4A5 COL4A6 NTRK3 ROR1 PTPRU RYK LONP1 PTPRD PTPRF SULF1 ADGRE3 PAK1 PAK2 PAK3 MVB12B

1.41e-0411869816GO:0007167
GeneOntologyBiologicalProcessastrocyte differentiation

MAG NTRK3 ROR1 MFSD8 CNTN2

1.45e-04105985GO:0048708
GeneOntologyBiologicalProcesspostsynaptic density organization

NTRK3 PTPRD PTPRS LRRTM2

1.67e-0458984GO:0097106
GeneOntologyBiologicalProcessstimulatory C-type lectin receptor signaling pathway

PAK1 PAK2 PAK3

1.72e-0423983GO:0002223
GeneOntologyBiologicalProcesscellular response to lectin

PAK1 PAK2 PAK3

1.72e-0423983GO:1990858
GeneOntologyBiologicalProcessresponse to lectin

PAK1 PAK2 PAK3

1.72e-0423983GO:1990840
GeneOntologyBiologicalProcessregulation of nervous system development

MAG NTRK3 ADGRB3 RYK PTPRD PTPRF FIG4 PTPRS LRRTM2 PAK1 PAK3

1.86e-046259811GO:0051960
GeneOntologyBiologicalProcessantigen processing and presentation, endogenous lipid antigen via MHC class Ib

CD1A CD1E

2.21e-045982GO:0048006
GeneOntologyBiologicalProcessnegative regulation of macrophage inflammatory protein 1 alpha production

SIRPB1 MEFV

2.21e-045982GO:0071641
GeneOntologyBiologicalProcesspyrimidine ribonucleotide biosynthetic process

NME2P1 CDA NME2

2.22e-0425983GO:0009220
GeneOntologyBiologicalProcessantigen processing and presentation via MHC class Ib

HLA-E CD1A CD1E

2.22e-0425983GO:0002475
GeneOntologyBiologicalProcessregulation of postsynaptic specialization assembly

PTPRD PTPRS LRRTM2

2.50e-0426983GO:0099150
GeneOntologyBiologicalProcessregulation of excitatory synapse assembly

PTPRD PTPRS LRRTM2

2.50e-0426983GO:1904889
GeneOntologyBiologicalProcessregulation of postsynaptic density organization

PTPRD PTPRS LRRTM2

2.80e-0427983GO:1905874
GeneOntologyBiologicalProcessregulation of extent of cell growth

MAG NTRK3 RYK PTPRS PAK1

2.92e-04122985GO:0061387
GeneOntologyBiologicalProcessaxon regeneration

MAG NTRK3 PTPRF PTPRS

3.27e-0469984GO:0031103
GeneOntologyBiologicalProcesspostsynaptic specialization organization

NTRK3 PTPRD PTPRS LRRTM2

3.65e-0471984GO:0099084
GeneOntologyBiologicalProcesssynapse organization

COL4A5 NTRK3 ADGRB3 RYK PTPRD PTPRF PTPRS LRRTM2 PAK1 PAK3 CNTN2

4.07e-046859811GO:0050808
GeneOntologyBiologicalProcessantigen processing and presentation, exogenous lipid antigen via MHC class Ib

CD1A CD1E

4.62e-047982GO:0048007
GeneOntologyBiologicalProcessantigen processing and presentation of lipid antigen via MHC class Ib

CD1A CD1E

4.62e-047982GO:0048003
GeneOntologyBiologicalProcessaxon extension

MAG NTRK3 RYK PTPRS PAK1

4.65e-04135985GO:0048675
GeneOntologyBiologicalProcessantigen processing and presentation of endogenous antigen

HLA-E CD1A CD1E

4.67e-0432983GO:0019883
GeneOntologyBiologicalProcesspyrimidine nucleotide biosynthetic process

NME2P1 CDA NME2

5.12e-0433983GO:0006221
GeneOntologyBiologicalProcesspyrimidine ribonucleotide metabolic process

NME2P1 CDA NME2

5.59e-0434983GO:0009218
GeneOntologyBiologicalProcesspeptidyl-tyrosine dephosphorylation

EPM2A PTPRF PTPRS

5.59e-0434983GO:0035335
GeneOntologyBiologicalProcessdendritic spine development

PTPRD PTPRS PAK1 PAK2 PAK3

5.67e-04141985GO:0060996
GeneOntologyBiologicalProcesspositive regulation of cell projection organization

NTRK3 ROR1 SAXO1 PTPRD PTPRF FIG4 PAK1 PAK3 NME2

5.75e-04494989GO:0031346
GeneOntologyBiologicalProcessneuron projection regeneration

MAG NTRK3 PTPRF PTPRS

6.02e-0481984GO:0031102
GeneOntologyBiologicalProcessregulation of macrophage inflammatory protein 1 alpha production

SIRPB1 MEFV

6.14e-048982GO:0071640
GeneOntologyBiologicalProcessregulation of anatomical structure morphogenesis

CYBB MAG COL4A3 NTRK3 ADGRB3 RYK PTPRD PTPRF PTPRS SULF1 PAK1 PAK2 PAK3 CNTN2

6.26e-0410909814GO:0022603
GeneOntologyBiologicalProcesscell junction organization

COL4A5 NTRK3 ADGRB3 RYK PTPRD PTPRF PTPRS LRRTM2 PAK1 PAK2 PAK3 ILDR1 CNTN2

6.97e-049749813GO:0034330
GeneOntologyBiologicalProcesspositive regulation of synapse assembly

NTRK3 ADGRB3 PTPRD LRRTM2

7.55e-0486984GO:0051965
GeneOntologyBiologicalProcessnegative regulation of axon extension

MAG RYK PTPRS

7.78e-0438983GO:0030517
GeneOntologyBiologicalProcessmacrophage inflammatory protein-1 alpha production

SIRPB1 MEFV

7.87e-049982GO:0071608
GeneOntologyBiologicalProcesscell morphogenesis involved in neuron differentiation

MAG NTRK3 ADGRB3 RYK PTPRD PTPRF PTPRS PAK1 PAK2 PAK3 CNTN2

8.44e-047489811GO:0048667
GeneOntologyBiologicalProcesspositive regulation of nervous system development

MAG NTRK3 ADGRB3 PTPRD PTPRF LRRTM2 PAK1 PAK3

8.54e-04418988GO:0051962
GeneOntologyBiologicalProcessregulation of axon regeneration

NTRK3 PTPRF PTPRS

9.05e-0440983GO:0048679
GeneOntologyBiologicalProcesstransepithelial chloride transport

CLCNKA CLCNKB

9.81e-0410982GO:0030321
GeneOntologyBiologicalProcessglomerular basement membrane development

COL4A3 SULF1

9.81e-0410982GO:0032836
GeneOntologyBiologicalProcesspostsynapse assembly

NTRK3 PTPRD PTPRS LRRTM2

1.01e-0393984GO:0099068
GeneOntologyBiologicalProcesspositive regulation of T cell mediated cytotoxicity

HLA-E CD1A CD1E

1.04e-0342983GO:0001916
GeneOntologyBiologicalProcesssynaptic membrane adhesion

PTPRD PTPRF PTPRS

1.04e-0342983GO:0099560
GeneOntologyBiologicalProcessneuron projection development

MAG NTRK3 ROR1 HLA-E ADGRB3 RYK PTPRD PTPRF FIG4 PTPRS PAK1 PAK2 PAK3 NME2 CNTN2

1.05e-0312859815GO:0031175
GeneOntologyBiologicalProcessdendrite development

ADGRB3 PTPRD PTPRF PTPRS PAK1 PAK2 PAK3

1.10e-03335987GO:0016358
GeneOntologyBiologicalProcesspyrimidine-containing compound biosynthetic process

NME2P1 CDA NME2

1.12e-0343983GO:0072528
GeneOntologyBiologicalProcessregulation of astrocyte differentiation

MAG NTRK3 CNTN2

1.12e-0343983GO:0048710
GeneOntologyBiologicalProcessUTP biosynthetic process

NME2P1 NME2

1.20e-0311982GO:0006228
GeneOntologyBiologicalProcesspositive regulation of neuron projection development

NTRK3 ROR1 PTPRD FIG4 PAK3 NME2

1.22e-03249986GO:0010976
GeneOntologyBiologicalProcessregeneration

MAG EPPK1 NTRK3 PTPRU PTPRF PTPRS

1.29e-03252986GO:0031099
GeneOntologyCellularComponentcollagen type IV trimer

COL4A3 COL4A5 COL4A6

1.86e-066963GO:0005587
GeneOntologyCellularComponentbasement membrane collagen trimer

COL4A3 COL4A5 COL4A6

5.17e-068963GO:0098651
GeneOntologyCellularComponentnetwork-forming collagen trimer

COL4A3 COL4A5 COL4A6

5.17e-068963GO:0098642
GeneOntologyCellularComponentcollagen network

COL4A3 COL4A5 COL4A6

5.17e-068963GO:0098645
GeneOntologyCellularComponentpostsynaptic membrane

NTRK3 ADGRB3 RYK SLC6A9 SLC6A11 PTPRF KCNC4 PTPRS LRRTM2 CNTN2

1.71e-054059610GO:0045211
GeneOntologyCellularComponentsynaptic membrane

NTRK3 ADGRB3 RYK SLC6A9 SLC6A11 PTPRD PTPRF KCNC4 PTPRS LRRTM2 CNTN2

7.47e-055839611GO:0097060
GeneOntologyCellularComponentcomplex of collagen trimers

COL4A3 COL4A5 COL4A6

1.18e-0421963GO:0098644
GeneOntologyCellularComponentneuron to neuron synapse

ADGRB3 RYK SLC6A9 PTPRD PTPRF PTPRS LRRTM2 PAK1 PAK2 PAK3

1.45e-045239610GO:0098984
GeneOntologyCellularComponentpostsynaptic density

ADGRB3 RYK SLC6A9 PTPRF PTPRS LRRTM2 PAK1 PAK2 PAK3

2.31e-04451969GO:0014069
GeneOntologyCellularComponentbasement membrane

COL4A3 COL4A5 COL4A6 FREM1 HMCN1

2.49e-04122965GO:0005604
GeneOntologyCellularComponentasymmetric synapse

ADGRB3 RYK SLC6A9 PTPRF PTPRS LRRTM2 PAK1 PAK2 PAK3

3.48e-04477969GO:0032279
GeneOntologyCellularComponentpostsynaptic specialization

ADGRB3 RYK SLC6A9 PTPRF PTPRS LRRTM2 PAK1 PAK2 PAK3

5.11e-04503969GO:0099572
GeneOntologyCellularComponentpostsynapse

NTRK3 ADGRB3 RYK SLC6A9 SLC6A11 PTPRF KCNC4 PTPRS LRRTM2 PAK1 PAK2 PAK3 CNTN2

7.60e-0410189613GO:0098794
GeneOntologyCellularComponentpostsynaptic density membrane

ADGRB3 RYK PTPRF PTPRS LRRTM2

7.91e-04157965GO:0098839
GeneOntologyCellularComponentexcitatory synapse

ADGRB3 SLC6A9 PTPRF LRRTM2

1.50e-03107964GO:0060076
GeneOntologyCellularComponentpresynaptic membrane

RYK SLC6A9 SLC6A11 PTPRD KCNC4 PTPRS

1.76e-03277966GO:0042734
GeneOntologyCellularComponentchloride channel complex

CLCNKA CLCNKB MFSD8

2.29e-0357963GO:0034707
GeneOntologyCellularComponentpostsynaptic specialization membrane

ADGRB3 RYK PTPRF PTPRS LRRTM2

2.36e-03201965GO:0099634
HumanPhenoNasogastric tube feeding

COL4A5 COL4A6 EPM2A CLCNKA CLCNKB

1.40e-0542395HP:0040288
HumanPhenoLenticonus

COL4A3 COL4A5 COL4A6

4.80e-0510393HP:0001142
HumanPhenoTracheobronchial leiomyomatosis

COL4A5 COL4A6

5.71e-052392HP:0006524
HumanPhenoDyspepsia

COL4A5 COL4A6

5.71e-052392HP:0410281
HumanPhenoDiffuse leiomyomatosis

COL4A5 COL4A6

5.71e-052392HP:0006756
HumanPhenoGlomerular basement membrane lamellation

COL4A3 COL4A5

1.71e-043392HP:0030034
HumanPhenoAnterior lenticonus

COL4A5 COL4A6

1.71e-043392HP:0011501
HumanPhenoVulvar neoplasm

COL4A5 COL4A6

1.71e-043392HP:0030416
HumanPhenoPrecordial pain

COL4A5 COL4A6

1.71e-043392HP:0032141
HumanPhenoAbnormal drug response

CES1 MEFV

1.71e-043392HP:0020169
HumanPhenoHypokalemic hypochloremic metabolic alkalosis

CLCNKA CLCNKB

1.71e-043392HP:0004909
HumanPhenoSevere failure to thrive

CLCNKA CLCNKB FIG4

2.62e-0417393HP:0001525
DomainIG_LIKE

MAG NTRK3 ROR1 HLA-E SIRPB1 PTPRU CD1A CD1E PTPRD PTPRF HMCN1 PTPRS ILDR1 CNTN2

1.59e-074919414PS50835
DomainIg-like_dom

MAG NTRK3 ROR1 HLA-E SIRPB1 PTPRU CD1A CD1E PTPRD PTPRF HMCN1 PTPRS ILDR1 CNTN2

2.14e-075039414IPR007110
Domain-

MAG EPM2A NTRK3 ROR1 HLA-E SIRPB1 PTPRU CD1A CD1E PTPRD PTPRF HMCN1 PTPRS ILDR1 CNTN2

1.06e-0666394152.60.40.10
DomainIg-like_fold

MAG EPM2A NTRK3 ROR1 HLA-E SIRPB1 PTPRU CD1A CD1E PTPRD PTPRF HMCN1 PTPRS ILDR1 CNTN2

2.30e-067069415IPR013783
DomainC4

COL4A3 COL4A5 COL4A6

2.44e-066943SM00111
Domain-

COL4A3 COL4A5 COL4A6

2.44e-0669432.170.240.10
DomainCollagen_VI_NC

COL4A3 COL4A5 COL4A6

2.44e-066943IPR001442
DomainC4

COL4A3 COL4A5 COL4A6

2.44e-066943PF01413
DomainPAK_BD

PAK1 PAK2 PAK3

2.44e-066943IPR033923
DomainNC1_IV

COL4A3 COL4A5 COL4A6

2.44e-066943PS51403
DomainTYR_PHOSPHATASE_2

EPM2A PTPRU PTPRD STYX PTPRF PTPRS

5.03e-0687946PS50056
DomainTYR_PHOSPHATASE_dom

EPM2A PTPRU PTPRD STYX PTPRF PTPRS

5.03e-0687946IPR000387
DomainIg_I-set

MAG NTRK3 ROR1 PTPRD PTPRF HMCN1 PTPRS CNTN2

5.22e-06190948IPR013098
DomainI-set

MAG NTRK3 ROR1 PTPRD PTPRF HMCN1 PTPRS CNTN2

5.22e-06190948PF07679
Domain-

EPM2A PTPRU PTPRD STYX PTPRF PTPRS

6.96e-06929463.90.190.10
DomainIG

MAG NTRK3 ROR1 SIRPB1 PTPRU PTPRD PTPRF HMCN1 PTPRS ILDR1 CNTN2

8.63e-064219411SM00409
DomainIg_sub

MAG NTRK3 ROR1 SIRPB1 PTPRU PTPRD PTPRF HMCN1 PTPRS ILDR1 CNTN2

8.63e-064219411IPR003599
DomainProt-tyrosine_phosphatase-like

EPM2A PTPRU PTPRD STYX PTPRF PTPRS

1.06e-0599946IPR029021
DomainPROTEIN_KINASE_ATP

NTRK3 ROR1 RYK STK10 TNNI3K CSNK1D CSNK1E PAK1 PAK2 PAK3 MAP3K2

1.93e-054599411PS00107
DomainCl_channel-K

CLCNKA CLCNKB

2.51e-052942IPR002250
Domain-

PAK1 PAK2 PAK3

2.63e-05129433.90.810.10
DomainPTPc

PTPRU PTPRD PTPRF PTPRS

3.13e-0536944SM00194
DomainTyr_Pase_AS

EPM2A PTPRU PTPRD PTPRF PTPRS

3.33e-0573945IPR016130
DomainProt_kinase_dom

NTRK3 ROR1 RYK STK10 TNNI3K CSNK1D CSNK1E PAK1 PAK2 PAK3 MAP3K2

3.45e-054899411IPR000719
DomainPROTEIN_KINASE_DOM

NTRK3 ROR1 RYK STK10 TNNI3K CSNK1D CSNK1E PAK1 PAK2 PAK3 MAP3K2

3.71e-054939411PS50011
DomainTYR_PHOSPHATASE_PTP

PTPRU PTPRD PTPRF PTPRS

4.32e-0539944PS50055
DomainPTPase_domain

PTPRU PTPRD PTPRF PTPRS

5.28e-0541944IPR000242
DomainY_phosphatase

PTPRU PTPRD PTPRF PTPRS

5.28e-0541944PF00102
DomainPBD

PAK1 PAK2 PAK3

6.59e-0516943SM00285
DomainTYR_PHOSPHATASE_1

EPM2A PTPRU PTPRD PTPRF PTPRS

7.32e-0586945PS00383
DomainPBD

PAK1 PAK2 PAK3

7.98e-0517943PF00786
DomainKinase-like_dom

NTRK3 ROR1 RYK STK10 TNNI3K CSNK1D CSNK1E PAK1 PAK2 PAK3 MAP3K2

8.70e-055429411IPR011009
DomainProtein_kinase_ATP_BS

NTRK3 STK10 TNNI3K CSNK1D CSNK1E PAK1 PAK2 PAK3 MAP3K2

1.24e-04379949IPR017441
DomainCRIB

PAK1 PAK2 PAK3

1.32e-0420943PS50108
DomainCRIB_dom

PAK1 PAK2 PAK3

1.54e-0421943IPR000095
DomainC1-set

HLA-E SIRPB1 CD1A CD1E

1.57e-0454944PF07654
DomainIGc1

HLA-E SIRPB1 CD1A CD1E

1.81e-0456944SM00407
DomainIGc2

MAG ROR1 PTPRD PTPRF HMCN1 PTPRS CNTN2

1.85e-04235947SM00408
DomainIg_sub2

MAG ROR1 PTPRD PTPRF HMCN1 PTPRS CNTN2

1.85e-04235947IPR003598
DomainIg_C1-set

HLA-E SIRPB1 CD1A CD1E

2.07e-0458944IPR003597
DomainPTPc_motif

PTPRU PTPRD PTPRF PTPRS

2.22e-0459944SM00404
DomainTyr_Pase_cat

PTPRU PTPRD PTPRF PTPRS

2.22e-0459944IPR003595
Domain-

HLA-E CD1A CD1E

2.31e-04249433.30.500.10
DomainMHC_I-like_Ag-recog

HLA-E CD1A CD1E

2.31e-0424943IPR011161
DomainMHC_I_3

CD1A CD1E

3.71e-046942PF16497
Domainig

MAG NTRK3 PTPRD HMCN1 PTPRS CNTN2

3.97e-04190946PF00047
DomainImmunoglobulin

MAG NTRK3 PTPRD HMCN1 PTPRS CNTN2

3.97e-04190946IPR013151
DomainSer/Thr_kinase_AS

STK10 TNNI3K CSNK1D CSNK1E PAK1 PAK2 PAK3 MAP3K2

4.39e-04357948IPR008271
DomainPROTEIN_KINASE_ST

STK10 TNNI3K CSNK1D CSNK1E PAK1 PAK2 PAK3 MAP3K2

4.82e-04362948PS00108
DomainWASP_C

PAK1 PAK2

5.18e-047942IPR011026
DomainCl-channel_core

CLCNKA CLCNKB

8.82e-049942IPR014743
DomainNDP_KINASES

NME2P1 NME2

8.82e-049942PS00469
Domain-

CLCNKA CLCNKB

8.82e-0499421.10.3080.10
DomainVoltage_CLC

CLCNKA CLCNKB

8.82e-049942PF00654
DomainCl-channel_volt-gated

CLCNKA CLCNKB

8.82e-049942IPR001807
DomainMHC_I/II-like_Ag-recog

HLA-E CD1A CD1E

9.17e-0438943IPR011162
DomainNDK

NME2P1 NME2

1.10e-0310942SM00562
DomainNDK

NME2P1 NME2

1.10e-0310942PF00334
DomainGAIN_dom_N

ADGRB3 ADGRE3

1.34e-0311942IPR032471
DomainGAIN

ADGRB3 ADGRE3

1.34e-0311942PF16489
Domainfn3

PTPRU PTPRD PTPRF PTPRS CNTN2

1.36e-03162945PF00041
DomainNucleoside_diP_kinase

NME2P1 NME2

1.60e-0312942IPR001564
DomainCTDL_fold

COL4A3 COL4A5 COL4A6 FREM1

2.09e-03107944IPR016187
DomainFN3

PTPRU PTPRD PTPRF PTPRS CNTN2

2.43e-03185945SM00060
DomainCBS

CLCNKA CLCNKB

2.87e-0316942SM00116
DomainPkinase

STK10 CSNK1D CSNK1E PAK1 PAK2 PAK3 MAP3K2

3.11e-03381947PF00069
DomainFN3

PTPRU PTPRD PTPRF PTPRS CNTN2

3.33e-03199945PS50853
DomainNA_NEUROTRAN_SYMP_2

SLC6A9 SLC6A11

3.64e-0318942PS00754
DomainSNF

SLC6A9 SLC6A11

4.05e-0319942PF00209
DomainNA_NEUROTRAN_SYMP_1

SLC6A9 SLC6A11

4.05e-0319942PS00610
DomainNA_NEUROTRAN_SYMP_3

SLC6A9 SLC6A11

4.05e-0319942PS50267
DomainNa/ntran_symport

SLC6A9 SLC6A11

4.05e-0319942IPR000175
DomainPkinase_Tyr

NTRK3 ROR1 RYK TNNI3K

4.10e-03129944PF07714
DomainFN3_dom

PTPRU PTPRD PTPRF PTPRS CNTN2

4.10e-03209945IPR003961
DomainCBS_dom

CLCNKA CLCNKB

4.49e-0320942IPR000644
DomainCBS

CLCNKA CLCNKB

4.49e-0320942PF00571
DomainCBS

CLCNKA CLCNKB

4.49e-0320942PS51371
DomainMHC_I

HLA-E CD1A

4.95e-0321942PF00129
DomainMHC_I_a_a1/a2

HLA-E CD1A

4.95e-0321942IPR001039
PathwayREACTOME_RECEPTOR_TYPE_TYROSINE_PROTEIN_PHOSPHATASES

NTRK3 PTPRD PTPRF PTPRS

3.36e-0620754M27290
PathwayREACTOME_RECEPTOR_TYPE_TYROSINE_PROTEIN_PHOSPHATASES

NTRK3 PTPRD PTPRF PTPRS

3.36e-0620754MM14991
PathwayBIOCARTA_NPP1_PATHWAY

COL4A3 COL4A5 COL4A6

1.69e-0510753M22040
PathwayBIOCARTA_NPP1_PATHWAY

COL4A3 COL4A5 COL4A6

1.69e-0510753MM1560
PathwayBIOCARTA_VITCB_PATHWAY

COL4A3 COL4A5 COL4A6

2.31e-0511753M15422
PathwayREACTOME_PROTEIN_PROTEIN_INTERACTIONS_AT_SYNAPSES

NTRK3 PTPRD PTPRF PTPRS LRRTM2

2.78e-0567755MM15327
PathwayBIOCARTA_VITCB_PATHWAY

COL4A3 COL4A5 COL4A6

3.07e-0512753MM1526
PathwayREACTOME_CD28_DEPENDENT_VAV1_PATHWAY

PAK1 PAK2 PAK3

3.07e-0512753M13618
PathwayREACTOME_CD28_DEPENDENT_VAV1_PATHWAY

PAK1 PAK2 PAK3

3.07e-0512753MM14994
PathwayBIOCARTA_ACE2_PATHWAY

COL4A3 COL4A5 COL4A6

3.98e-0513753MM1347
PathwayBIOCARTA_ACE2_PATHWAY

COL4A3 COL4A5 COL4A6

3.98e-0513753M12950
PathwayREACTOME_ACTIVATION_OF_RAC1

PAK1 PAK2 PAK3

3.98e-0513753M6322
PathwayREACTOME_SEMA3A_PAK_DEPENDENT_AXON_REPULSION

PAK1 PAK2 PAK3

5.05e-0514753MM15029
PathwayBIOCARTA_PLATELETAPP_PATHWAY

COL4A3 COL4A5 COL4A6

5.05e-0514753MM1458
PathwayBIOCARTA_PLATELETAPP_PATHWAY

COL4A3 COL4A5 COL4A6

5.05e-0514753M6487
PathwayREACTOME_ANCHORING_FIBRIL_FORMATION

COL4A3 COL4A5 COL4A6

6.29e-0515753M27161
PathwayREACTOME_LAMININ_INTERACTIONS

COL4A3 COL4A5 COL4A6

6.29e-0515753MM14922
PathwayREACTOME_SIGNALING_BY_RECEPTOR_TYROSINE_KINASES

CYBB COL4A3 COL4A5 NTRK3 POLR2A PTPRU PTPRF PAK1 PAK2 PAK3

6.99e-054187510MM15587
PathwayREACTOME_SEMA3A_PAK_DEPENDENT_AXON_REPULSION

PAK1 PAK2 PAK3

7.71e-0516753M16498
PathwayREACTOME_CD209_DC_SIGN_SIGNALING

PAK1 PAK2 PAK3

9.32e-0517753MM15215
PathwayREACTOME_PROTEIN_PROTEIN_INTERACTIONS_AT_SYNAPSES

NTRK3 PTPRD PTPRF PTPRS LRRTM2

9.80e-0587755M27617
PathwayWP_PLEURAL_MESOTHELIOMA

COL4A3 COL4A5 COL4A6 ROR1 RYK CSNK1E PAK1 PAK2 PAK3 MAP3K2

1.05e-044397510M42563
PathwayREACTOME_SIGNALING_BY_RECEPTOR_TYROSINE_KINASES

CYBB COL4A3 COL4A5 NTRK3 POLR2A PTPRU PTPRF PTPRS PAK1 PAK2 PAK3

1.09e-045327511M27870
PathwayREACTOME_EPHRIN_SIGNALING

PAK1 PAK2 PAK3

1.11e-0418753MM15024
PathwayREACTOME_CROSSLINKING_OF_COLLAGEN_FIBRILS

COL4A3 COL4A5 COL4A6

1.11e-0418753M27164
PathwayREACTOME_CROSSLINKING_OF_COLLAGEN_FIBRILS

COL4A3 COL4A5 COL4A6

1.11e-0418753MM14882
PathwayREACTOME_EPHRIN_SIGNALING

PAK1 PAK2 PAK3

1.32e-0419753M27310
PathwayWP_WNT_SIGNALING_WP363

ROR1 RYK CSNK1D CSNK1E

1.53e-0451754M39721
PathwayBIOCARTA_AMI_PATHWAY

COL4A3 COL4A5 COL4A6

1.55e-0420753M15394
PathwayREACTOME_SYNAPTIC_ADHESION_LIKE_MOLECULES

PTPRD PTPRF PTPRS

1.55e-0420753MM15485
PathwayREACTOME_SYNAPTIC_ADHESION_LIKE_MOLECULES

PTPRD PTPRF PTPRS

1.80e-0421753M27736
PathwayREACTOME_CD209_DC_SIGN_SIGNALING

PAK1 PAK2 PAK3

1.80e-0421753M27485
PathwayREACTOME_RHO_GTPASES_ACTIVATE_PAKS

PAK1 PAK2 PAK3

1.80e-0421753M27494
PathwayBIOCARTA_INTRINSIC_PATHWAY

COL4A3 COL4A5 COL4A6

2.37e-0423753M15997
PathwayBIOCARTA_INTRINSIC_PATHWAY

COL4A3 COL4A5 COL4A6

2.37e-0423753MM1427
PathwayREACTOME_RHO_GTPASES_ACTIVATE_PAKS

PAK1 PAK2 PAK3

2.37e-0423753MM15222
PathwayREACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES

PAK1 PAK2 PAK3

3.86e-0427753MM14809
PathwayREACTOME_VEGFR2_MEDIATED_VASCULAR_PERMEABILITY

PAK1 PAK2 PAK3

3.86e-0427753M27422
PathwayREACTOME_LAMININ_INTERACTIONS

COL4A3 COL4A5 COL4A6

5.30e-0430753M27216
PathwayPID_P38_ALPHA_BETA_PATHWAY

PAK1 PAK2 PAK3

5.30e-0430753M76
PathwayREACTOME_VEGFR2_MEDIATED_VASCULAR_PERMEABILITY

PAK1 PAK2 PAK3

5.30e-0430753MM15170
PathwayBIOCARTA_AGR_PATHWAY

PAK1 PAK2 PAK3

5.84e-0431753MM1343
PathwayREACTOME_MAPK6_MAPK4_SIGNALING

PSMB4 PAK1 PAK2 PAK3

6.09e-0473754MM15285
PathwayREACTOME_NON_INTEGRIN_MEMBRANE_ECM_INTERACTIONS

COL4A3 COL4A5 COL4A6

6.42e-0432753MM14924
PathwayBIOCARTA_AGR_PATHWAY

PAK1 PAK2 PAK3

7.04e-0433753M6220
PathwayREACTOME_CD28_CO_STIMULATION

PAK1 PAK2 PAK3

7.04e-0433753M11725
PathwayREACTOME_ECM_PROTEOGLYCANS

COL4A3 COL4A5 COL4A6 PTPRS

7.10e-0476754M27219
PathwayREACTOME_CD28_CO_STIMULATION

PAK1 PAK2 PAK3

7.69e-0434753MM14992
PathwaySIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES

PAK1 PAK2 PAK3

8.38e-0435753M16801
PathwayREACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES

PAK1 PAK2 PAK3

1.15e-0339753M16523
PathwayREACTOME_RHOU_GTPASE_CYCLE

PAK1 PAK2 PAK3

1.15e-0339753MM15607
PathwayWP_NEURAL_CREST_CELL_MIGRATION_DURING_DEVELOPMENT

PAK1 PAK2 PAK3

1.24e-0340753M39798
PathwayREACTOME_RHOU_GTPASE_CYCLE

PAK1 PAK2 PAK3

1.24e-0340753M41816
PathwayREACTOME_COLLAGEN_CHAIN_TRIMERIZATION

COL4A3 COL4A5 COL4A6

1.33e-0341753MM15538
PathwayREACTOME_HIV_INFECTION

POLR2A PSMB4 SSRP1 PAK2 NUP188 MVB12B

1.42e-03231756M12469
PathwayREACTOME_NCAM1_INTERACTIONS

COL4A3 COL4A5 CNTN2

1.43e-0342753M7169
PathwayREACTOME_CREATINE_METABOLISM

GAMT SLC6A11

1.49e-0311752M27681
PathwayREACTOME_CREATINE_METABOLISM

GAMT SLC6A11

1.49e-0311752MM15402
PathwayREACTOME_MAPK6_MAPK4_SIGNALING

PSMB4 PAK1 PAK2 PAK3

1.51e-0393754M27572
PathwayWP_NEURAL_CREST_CELL_MIGRATION_IN_CANCER

PAK1 PAK2 PAK3

1.53e-0343753M39788
PathwayPID_INTEGRIN3_PATHWAY

COL4A3 COL4A5 COL4A6

1.53e-0343753M53
PathwayREACTOME_COLLAGEN_CHAIN_TRIMERIZATION

COL4A3 COL4A5 COL4A6

1.64e-0344753M27812
PathwaySIG_CHEMOTAXIS

PAK1 PAK2 PAK3

1.75e-0345753M5193
PathwayPID_SYNDECAN_1_PATHWAY

COL4A3 COL4A5 COL4A6

1.86e-0346753M198
PathwayWP_MECHANOREGULATION_AND_PATHOLOGY_OF_YAPTAZ_VIA_HIPPO_AND_NONHIPPO_MECHANISMS

PAK1 PAK2 PAK3

1.98e-0347753M39829
PathwayREACTOME_NEURONAL_SYSTEM

NTRK3 SLC6A11 PTPRD PTPRF KCNC4 PTPRS LRRTM2

2.00e-03335757MM14503
PathwayKEGG_CIRCADIAN_RHYTHM_MAMMAL

CSNK1D CSNK1E

2.10e-0313752M18009
PathwayREACTOME_SIGNALING_BY_VEGF

CYBB PAK1 PAK2 PAK3

2.20e-03103754MM14752
PathwayREACTOME_ASSEMBLY_OF_COLLAGEN_FIBRILS_AND_OTHER_MULTIMERIC_STRUCTURES

COL4A3 COL4A5 COL4A6

2.37e-0350753MM14796
PathwayREACTOME_SIGNALING_BY_VEGF

CYBB PAK1 PAK2 PAK3

2.44e-03106754M27077
PathwayREACTOME_SEMAPHORIN_INTERACTIONS

PAK1 PAK2 PAK3

2.51e-0351753MM14967
PathwayREACTOME_COLLAGEN_DEGRADATION

COL4A3 COL4A5 COL4A6

2.80e-0353753MM14566
PathwayREACTOME_METABOLISM_OF_ANGIOTENSINOGEN_TO_ANGIOTENSINS

CES1 ENPEP

2.80e-0315752MM14797
PathwayREACTOME_TCR_SIGNALING

PSMB4 PAK1 PAK2 PAK3

2.88e-03111754MM14803
PathwayPID_RAC1_PATHWAY

CYBB PAK1 PAK2

2.95e-0354753M278
PathwayREACTOME_C_TYPE_LECTIN_RECEPTORS_CLRS

PSMB4 PAK1 PAK2 PAK3

2.98e-03112754MM15214
PathwayREACTOME_RHOJ_GTPASE_CYCLE

PAK1 PAK2 PAK3

3.11e-0355753M41815
PathwayREACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX

COL4A3 COL4A5 COL4A6 MMP16

3.17e-03114754MM14571
PathwayREACTOME_METABOLISM_OF_ANGIOTENSINOGEN_TO_ANGIOTENSINS

CES1 ENPEP

3.61e-0317752M27104
PathwayREACTOME_SIGNALING_BY_NTRK3_TRKC

NTRK3 PTPRS

3.61e-0317752M27918
PathwayWP_MET_IN_TYPE_1_PAPILLARY_RENAL_CELL_CARCINOMA

PAK1 PAK2 PAK3

3.80e-0359753M39750
PathwayREACTOME_NON_INTEGRIN_MEMBRANE_ECM_INTERACTIONS

COL4A3 COL4A5 COL4A6

3.80e-0359753M27218
Pubmed

Identification of orphan ligand-receptor relationships using a cell-based CRISPRa enrichment screening platform.

ROR1 PTPRU PTPRD PTPRF PTPRS

1.01e-082698536178190
Pubmed

PTPσ functions as a presynaptic receptor for the glypican-4/LRRTM4 complex and is essential for excitatory synaptic transmission.

NTRK3 PTPRD PTPRF PTPRS

1.93e-081198425624497
Pubmed

Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion.

ROR1 PTPRU PTPRD PTPRF HMCN1 PTPRS ILDR1 CNTN2

2.05e-0816298825826454
Pubmed

Multisite autophosphorylation of p21-activated protein kinase gamma-PAK as a function of activation.

PAK1 PAK2 PAK3

2.17e-08398310075701
Pubmed

Altered cortical synaptic morphology and impaired memory consolidation in forebrain- specific dominant-negative PAK transgenic mice.

PAK1 PAK2 PAK3

2.17e-08398315182717
Pubmed

The Rac GTPase effector p21-activated kinase is essential for hematopoietic stem/progenitor cell migration and engraftment.

PAK1 PAK2 PAK3

2.17e-08398323335370
Pubmed

Group I Paks as therapeutic targets in NF2-deficient meningioma.

PAK1 PAK2 PAK3

2.17e-08398325596744
Pubmed

LAR receptor phospho-tyrosine phosphatases regulate NMDA-receptor responses.

PTPRD PTPRF PTPRS

2.17e-08398331985401
Pubmed

Trans-synaptic adhesions between netrin-G ligand-3 (NGL-3) and receptor tyrosine phosphatases LAR, protein-tyrosine phosphatase delta (PTPdelta), and PTPsigma via specific domains regulate excitatory synapse formation.

PTPRD PTPRF PTPRS

2.17e-08398320139422
Pubmed

Developmental expression of the cell adhesion molecule-like protein tyrosine phosphatases LAR, RPTPdelta and RPTPsigma in the mouse.

PTPRD PTPRF PTPRS

2.17e-0839839784606
Pubmed

Intact synapse structure and function after combined knockout of PTPδ, PTPσ, and LAR.

PTPRD PTPRF PTPRS

2.17e-08398333656439
Pubmed

The four mammalian splice variants encoded by the p21-activated kinase 3 gene have different biological properties.

PAK1 PAK2 PAK3

2.17e-08398318507705
Pubmed

COL4A6 is dispensable for autosomal recessive Alport syndrome.

COL4A3 COL4A5 COL4A6

2.17e-08398327377778
Pubmed

Porocarcinomas with PAK1/2/3 fusions: a series of 12 cases.

PAK1 PAK2 PAK3

2.17e-08398338785043
Pubmed

The mechanism of PAK activation. Autophosphorylation events in both regulatory and kinase domains control activity.

PAK1 PAK2 PAK3

2.17e-08398311278486
Pubmed

Liprins, a family of LAR transmembrane protein-tyrosine phosphatase-interacting proteins.

PTPRU PTPRD PTPRF PTPRS

2.88e-08129849624153
Pubmed

The LAR/PTP delta/PTP sigma subfamily of transmembrane protein-tyrosine-phosphatases: multiple human LAR, PTP delta, and PTP sigma isoforms are expressed in a tissue-specific manner and associate with the LAR-interacting protein LIP.1.

PTPRD PTPRF PTPRS

8.66e-0849838524829
Pubmed

Pak to the future.

PAK1 PAK2 PAK3

8.66e-08498310461188
Pubmed

CHL1 cooperates with PAK1-3 to regulate morphological differentiation of embryonic cortical neurons.

PAK1 PAK2 PAK3

8.66e-08498319819308
Pubmed

Identification of a novel cell-adhesive protein spatiotemporally expressed in the basement membrane of mouse developing hair follicle.

COL4A3 COL4A5 COL4A6 FREM1

1.05e-071698415878328
Pubmed

Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.

CES1 POLR2A USP24 PTPRU SULT2B1 KCNC4 CSNK1D CSNK1E PAK1 PAK2 CORO6 EIF3C MMP16

1.44e-07730981334857952
Pubmed

Multiple interactions between receptor protein-tyrosine phosphatase (RPTP) alpha and membrane-distal protein-tyrosine phosphatase domains of various RPTPs.

PTPRD PTPRF PTPRS

2.16e-07598310777529
Pubmed

Rescue of fragile X syndrome phenotypes in Fmr1 KO mice by the small-molecule PAK inhibitor FRAX486.

PAK1 PAK2 PAK3

2.16e-07598323509247
Pubmed

Interleukin-1 receptor accessory protein organizes neuronal synaptogenesis as a cell adhesion molecule.

PTPRD PTPRF PTPRS

2.16e-07598322357843
Pubmed

Stimulation of extracellular matrix components in the normal brain by invading glioma cells.

COL4A3 COL4A5 COL4A6

4.31e-0769839506531
Pubmed

Maturation of ureter-bladder connection in mice is controlled by LAR family receptor protein tyrosine phosphatases.

PTPRD PTPRF PTPRS

4.31e-07698319273906
Pubmed

Synapsin I is phosphorylated at Ser603 by p21-activated kinases (PAKs) in vitro and in PC12 cells stimulated with bradykinin.

PAK1 PAK2 PAK3

4.31e-07698312237306
Pubmed

Extracellular matrix of the human optic nerve head.

COL4A3 COL4A5 COL4A6

4.31e-0769832426947
Pubmed

Mice carrying a schizophrenia-associated mutation of the Arhgap10 gene are vulnerable to the effects of methamphetamine treatment on cognitive function: association with morphological abnormalities in striatal neurons.

PAK1 PAK2 PAK3

4.31e-07698333482876
Pubmed

Pak1 is involved in dendrite initiation as a downstream effector of Rac1 in cortical neurons.

PAK1 PAK2 PAK3

4.31e-07698312213441
Pubmed

Angiogenesis and collagen type IV expression in different endothelial cell culture systems.

COL4A3 COL4A5 COL4A6

4.31e-07698323551189
Pubmed

Monoclonal antibody to human basement membrane collagen type IV.

COL4A3 COL4A5 COL4A6

4.31e-0769836811420
Pubmed

Immunolocalization of collagen types, laminin and fibronectin in the normal human pancreas.

COL4A3 COL4A5 COL4A6

4.31e-0769836389236
Pubmed

Collagen IV in the developing lens capsule.

COL4A3 COL4A5 COL4A6

4.31e-07698312225806
Pubmed

Insertional mutation of the collagen genes Col4a3 and Col4a4 in a mouse model of Alport syndrome.

COL4A3 COL4A5 COL4A6

4.31e-07698310534397
Pubmed

A tumor derived motility factor that stimulates cell migration on extracellular matrix.

COL4A3 COL4A5 COL4A6

4.31e-0769839673377
Pubmed

Localization of type IV collagen a 1 to a 6 chains in basement membrane during mouse molar germ development.

COL4A3 COL4A5 COL4A6

4.31e-07698311732842
Pubmed

Developmental distribution of collagen IV isoforms and relevance to ocular diseases.

COL4A3 COL4A5 COL4A6

4.31e-07698319275937
Pubmed

Distribution of basement membrane proteins in normal and fibrotic human liver: collagen type IV, laminin, and fibronectin.

COL4A3 COL4A5 COL4A6

4.31e-0769836988303
Pubmed

Modulation of apoptotic response by LAR family phosphatases-cIAP1 signaling during urinary tract morphogenesis.

PTPRD PTPRF PTPRS

7.53e-07798329073098
Pubmed

Interstitial collagens I, III, and VI sequester and modulate the multifunctional cytokine oncostatin M.

COL4A3 COL4A5 COL4A6

7.53e-07798311711546
Pubmed

Intra- and intermolecular interactions between intracellular domains of receptor protein-tyrosine phosphatases.

PTPRD PTPRF PTPRS

7.53e-07798312376545
Pubmed

Regulation of protease nexin-1 target protease specificity by collagen type IV.

COL4A3 COL4A5 COL4A6

7.53e-0779838006028
Pubmed

Corneal cell proteins and ocular surface pathology.

COL4A3 COL4A5 COL4A6

7.53e-07798310416788
Pubmed

Purification, partial characterization of rat kidney hyaluronic acid binding protein and its localization on the cell surface.

COL4A3 COL4A5 COL4A6

7.53e-0779831724753
Pubmed

Distinct target-derived signals organize formation, maturation, and maintenance of motor nerve terminals.

COL4A3 COL4A5 COL4A6

7.53e-07798317418794
Pubmed

Multifocal motor neuropathy is not associated with genetic variation in PTPN22, BANK1, Blk, FCGR2B, CD1A/E, and TAG-1 genes.

CD1A CD1E CNTN2

7.53e-07798322003931
Pubmed

Appearance and persistence of fibronectin in cartilage. Specific interaction of fibronectin with collagen type II.

COL4A3 COL4A5 COL4A6

1.20e-0689833997552
Pubmed

Type IV collagen α6 chain is a regulator of keratin 10 in keratinization of oral mucosal epithelium.

COL4A3 COL4A5 COL4A6

1.20e-06898329422532
Pubmed

Short amino acid sequences derived from C1q receptor (C1q-R) show homology with the alpha chains of fibronectin and vitronectin receptors and collagen type IV.

COL4A3 COL4A5 COL4A6

1.20e-0689831377218
Pubmed

Combinatorial expression of neurexins and LAR-type phosphotyrosine phosphatase receptors instructs assembly of a cerebellar circuit.

PTPRD PTPRF PTPRS

1.20e-06898337591863
Pubmed

Protein Tyrosine Phosphatase δ Mediates the Sema3A-Induced Cortical Basal Dendritic Arborization through the Activation of Fyn Tyrosine Kinase.

PTPRD PTPRF PTPRS

1.20e-06898328637841
Pubmed

Transforming growth factor-beta and p-21: multiple molecular targets of decorin-mediated suppression of neoplastic growth.

COL4A3 COL4A5 COL4A6

1.20e-06898310382266
Pubmed

Discoidin domain receptor 1 functions in axon extension of cerebellar granule neurons.

COL4A3 COL4A5 COL4A6

1.20e-06898310970885
Pubmed

MMP-9 from TNF alpha-stimulated keratinocytes binds to cell membranes and type I collagen: a cause for extended matrix degradation in inflammation?

COL4A3 COL4A5 COL4A6

1.80e-0699839878537
Pubmed

Krüppel-like zinc-finger transcription factor KLF5/BTEB2 is a target for angiotensin II signaling and an essential regulator of cardiovascular remodeling.

COL4A3 COL4A5 COL4A6

1.80e-06998312101409
Pubmed

Functional characterization of the human immunodeficiency virus type 1 Nef acidic domain.

HLA-E PAK1 PAK2

2.57e-061098318653452
Pubmed

Interaction between Alzheimer's disease beta A4 precursor protein (APP) and the extracellular matrix: evidence for the participation of heparan sulfate proteoglycans.

COL4A3 COL4A5 COL4A6

2.57e-06109839136074
Pubmed

Collagen IV is essential for basement membrane stability but dispensable for initiation of its assembly during early development.

COL4A3 COL4A5 COL4A6

3.52e-061198314998921
Pubmed

Binding of mouse and human fibulin-2 to extracellular matrix ligands.

COL4A3 COL4A5 COL4A6

3.52e-06119837500359
Pubmed

A novel receptor-type protein tyrosine phosphatase with a single catalytic domain is specifically expressed in mouse brain.

PTPRD PTPRF PTPRS

3.52e-06119837832766
Pubmed

Sensory ataxia and muscle spindle agenesis in mice lacking the transcription factor Egr3.

COL4A3 COL4A5 NTRK3

3.52e-06119839731539
Pubmed

Cloning, central nervous system expression and chromosomal mapping of the mouse PAK-1 and PAK-3 genes.

PAK1 PAK2 PAK3

3.52e-061198310352232
Pubmed

A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.

EPM2A PSMB4 PTPRU PTPRD STYX PTPRF PTPRS CSNK1D CSNK1E EIF3C NUP188 PRRC2A ABTB2

3.59e-06974981328675297
Pubmed

Wnt signaling is required for organization of the lens fiber cell cytoskeleton and development of lens three-dimensional architecture.

PAK1 PAK2 PAK3

4.69e-061298318824165
Pubmed

Matrilin-2 interacts with itself and with other extracellular matrix proteins.

COL4A3 COL4A5 COL4A6

4.69e-061298312180907
Pubmed

In-silico designing of a potent analogue against HIV-1 Nef protein and protease by predicting its interaction network with host cell proteins.

PSMB4 PAK1 PAK2

4.69e-061298323559827
Pubmed

Basement membrane fragility underlies embryonic lethality in fukutin-null mice.

COL4A3 COL4A5 COL4A6

4.69e-061298315837576
Pubmed

Compound genetic ablation of nidogen 1 and 2 causes basement membrane defects and perinatal lethality in mice.

COL4A3 COL4A5 COL4A6

4.69e-061298316024816
Pubmed

Loss of ARHGEF6 Causes Hair Cell Stereocilia Deficits and Hearing Loss in Mice.

PAK1 PAK2 PAK3

6.08e-061398330333726
Pubmed

PAK is regulated by PI3K, PIX, CDC42, and PP2Calpha and mediates focal adhesion turnover in the hyperosmotic stress-induced p38 pathway.

PAK1 PAK2 PAK3

7.72e-061498318586681
Pubmed

Characterization of the enzymatic activity of human kallikrein 6: Autoactivation, substrate specificity, and regulation by inhibitors.

COL4A3 COL4A5 COL4A6

7.72e-061498312878203
Pubmed

Cloning, tissue distribution, and intrarenal localization of ClC chloride channels in human kidney.

CLCNKA CLCNKB

7.86e-0629828544406
Pubmed

Activation of PAK1/2 during the shedding of platelet microvesicles.

PAK1 PAK2

7.86e-06298220523167
Pubmed

Association of CD1A +622 T/C, +737 G/C and CD1E +6129 A/G genes polymorphisms with multiple sclerosis.

CD1A CD1E

7.86e-06298220954848
Pubmed

CD1A and CD1E gene polymorphisms are associated with susceptibility to multiple sclerosis.

CD1A CD1E

7.86e-06298221496400
Pubmed

The ClC-K2 Chloride Channel Is Critical for Salt Handling in the Distal Nephron.

CLCNKA CLCNKB

7.86e-06298227335120
Pubmed

PAK1, PAK1Δ15, and PAK2: similarities, differences and mutual interactions.

PAK1 PAK2

7.86e-06298231748572
Pubmed

Casein kinase I delta/epsilon phosphorylates topoisomerase IIalpha at serine-1106 and modulates DNA cleavage activity.

CSNK1D CSNK1E

7.86e-06298219043076
Pubmed

Assignment of the genes encoding the human chloride channels, CLCNKA and CLCNKB, to 1p36 and of CLCN3 to 4q32-q33 by in situ hybridization.

CLCNKA CLCNKB

7.86e-0629828812470
Pubmed

Sensitive and high resolution in situ hybridization to human chromosomes using biotin labelled probes: assignment of the human thymocyte CD1 antigen genes to chromosome 1.

CD1A CD1E

7.86e-0629823053166
Pubmed

Associations between CLCNKA_B tag SNPs with essential hypertension and interactions between genetic and environmental factors in an island population in China.

CLCNKA CLCNKB

7.86e-06298225919862
Pubmed

Group I p21-activated kinases facilitate Tax-mediated transcriptional activation of the human T-cell leukemia virus type 1 long terminal repeats.

PAK1 PAK3

7.86e-06298223622267
Pubmed

Targeting kidney CLC-K channels: pharmacological profile in a human cell line versus Xenopus oocytes.

CLCNKA CLCNKB

7.86e-06298224863058
Pubmed

CK1δ and CK1ε are components of human 40S subunit precursors required for cytoplasmic 40S maturation.

CSNK1D CSNK1E

7.86e-06298224424021
Pubmed

Overt nephrogenic diabetes insipidus in mice lacking the CLC-K1 chloride channel.

CLCNKA CLCNKB

7.86e-0629829916798
Pubmed

Kidney kinetics and chloride ion pumps.

CLCNKA CLCNKB

7.86e-0629829916791
Pubmed

Alphaherpesvirus US3-mediated reorganization of the actin cytoskeleton is mediated by group A p21-activated kinases.

PAK1 PAK2

7.86e-06298219435845
Pubmed

Salmonella evades D-amino acid oxidase to promote infection in neutrophils.

CYBB DAO

7.86e-06298225425233
Pubmed

Postsynaptic TrkC and presynaptic PTPσ function as a bidirectional excitatory synaptic organizing complex.

NTRK3 PTPRS

7.86e-06298221262467
Pubmed

Solution structures and biophysical analysis of full-length group A PAKs reveal they are monomeric and auto-inhibited in cis.

PAK1 PAK3

7.86e-06298230858169
Pubmed

p21-Activated kinases 1 and 3 control brain size through coordinating neuronal complexity and synaptic properties.

PAK1 PAK3

7.86e-06298221115725
Pubmed

Deletion of the paired alpha 5(IV) and alpha 6(IV) collagen genes in inherited smooth muscle tumors.

COL4A5 COL4A6

7.86e-0629828356449
Pubmed

Regulation of casein kinase I epsilon and casein kinase I delta by an in vivo futile phosphorylation cycle.

CSNK1D CSNK1E

7.86e-0629829632646
Pubmed

Characterization of the human nm23-H2 promoter region and localization of the microsatellite D17S396.

NME2P1 NME2

7.86e-0629827488060
Pubmed

CD1A and CD1E gene polymorphisms are not associated with susceptibility to Guillain-Barré syndrome in the Bangladeshi population.

CD1A CD1E

7.86e-06298229301656
Pubmed

Genotype-phenotype correlations for COL4A3-COL4A5 variants resulting in Gly substitutions in Alport syndrome.

COL4A3 COL4A5

7.86e-06298235177655
Pubmed

Expanding Genotype-Phenotype Correlation of CLCNKA and CLCNKB Variants Linked to Hearing Loss.

CLCNKA CLCNKB

7.86e-06298238069401
Pubmed

Constitutive p21-activated kinase (PAK) activation in breast cancer cells as a result of mislocalization of PAK to focal adhesions.

PAK1 PAK2

7.86e-06298215047871
Pubmed

Expression of p21-activated kinases 1 and 3 is altered in the brain of subjects with depression.

PAK1 PAK3

7.86e-06298227474226
InteractionOMG interactions

PTPRU PTPRD PTPRF PTPRS

2.58e-0713904int:OMG
InteractionPTPRD interactions

RYK PTPRD PTPRF PTPRS CSNK1D CSNK1E LRRTM2

1.99e-06131907int:PTPRD
InteractionMICU2 interactions

CMTR1 ASH2L LACTB CSNK1D CSNK1E ABTB2

3.98e-0694906int:MICU2
InteractionPTPRS interactions

NTRK3 PTPRU RYK PTPRD PTPRF PTPRS NME2

5.59e-06153907int:PTPRS
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

MAG NTRK3 ROR1 PTPRD PTPRF HMCN1 PTPRS CNTN2

1.09e-07161658593
GeneFamilyProtein tyrosine phosphatases, receptor type

PTPRU PTPRD PTPRF PTPRS

8.70e-0721654813
GeneFamilyC1-set domain containing

HLA-E SIRPB1 CD1A CD1E

1.54e-0542654591
GeneFamilyFibronectin type III domain containing

PTPRU PTPRD PTPRF PTPRS CNTN2

2.74e-04160655555
GeneFamilyReceptor Tyrosine Kinases|CD molecules

NTRK3 ROR1 RYK

3.98e-0440653321
GeneFamilyChloride voltage-gated channels

CLCNKA CLCNKB

5.62e-0410652302
GeneFamilyCollagens

COL4A3 COL4A5 COL4A6

6.03e-0446653490
GeneFamilyAtypical dual specificity phosphatases

EPM2A STYX

1.88e-0318652896
CoexpressionYOSHIMURA_MAPK8_TARGETS_UP

CYBB MAG AMPD1 CES1 NTRK3 PSMB4 HLA-E PTPRU SLC6A9 SLC6A11 PTPRF CLCNKA CLCNKB KCNC4 CSNK1D PAK3 CNTN2

2.76e-0612819417M1884
CoexpressionGSE360_HIGH_DOSE_B_MALAYI_VS_M_TUBERCULOSIS_MAC_UP

GPR39 USP24 SIRPB1 STK10 FIG4 CDA NUP188

7.66e-06199947M5263
CoexpressionHEBERT_MATRISOME_TNBC_BRAIN_METASTASIS_TUMOR_CELL_DERIVED

COL4A5 FREM1 HMCN1

9.60e-0612943M47998
CoexpressionNABA_BASEMENT_MEMBRANES

COL4A3 COL4A5 COL4A6 HMCN1

1.28e-0540944M5887
CoexpressionZHANG_TARGETS_OF_EWSR1_FLI1_FUSION

CES1 HLA-E SLC1A4 CD1E CSNK1E

1.56e-0587945M18322
CoexpressionDESCARTES_FETAL_LIVER_MESOTHELIAL_CELLS

COL4A3 COL4A6 TRABD2B NTRK3 PTPRU PTPRD PTPRF SULF1

1.73e-05313948M40228
CoexpressionDING_LUNG_CANCER_EXPRESSION_BY_COPY_NUMBER

VPS8 ASH2L RYK FIG4 PAK2

3.07e-05100945M14670
CoexpressionGSE7509_UNSTIM_VS_FCGRIIB_STIM_DC_UP

GAMT ROR1 PTPRU RYK CSNK1E CORO6

3.94e-05174946M6817
CoexpressionFERRANDO_HOX11_NEIGHBORS

CD1A CD1E PTPRF

7.51e-0523943M2059
CoexpressionGSE360_LOW_DOSE_B_MALAYI_VS_M_TUBERCULOSIS_MAC_UP

GPR39 SIRPB1 CD1E FIG4 CDA NUP188

8.30e-05199946M5266
CoexpressionDING_LUNG_CANCER_MUTATED_SIGNIFICANTLY

NTRK3 PTPRD PAK3

1.09e-0426943M16488
CoexpressionHEBERT_MATRISOME_TNBC_BRAIN_METASTASIS

COL4A5 FREM1 HMCN1

1.09e-0426943M47999
CoexpressionAtlasdev lower uro neuro_e15.5_PelvicGanglion_Sox10_k-means-cluster#2_top-relative-expression-ranked_500

ROR1 FREM1 HMCN1 SULF1 MMP16 ENPEP

1.90e-05127926gudmap_dev lower uro neuro_e15.5_PelvicGanglion_Sox10_k2_500
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A3 TRABD2B USP24 FREM1 HMCN1 CLCNKA CLCNKB

1.39e-07188937eec3d353e51358db4c7621265ee0fdd4298e5b0e
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL4A5 TRABD2B NTRK3 ROR1 PTPRS PAK3 ABTB2

1.44e-0718993745e588b2a4ad9e3ff74e22d9d627ed3571f3b8b8
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_adventitial_fibro_(9)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

PLSCR4 CES1 ADGRB3 FREM1 SULF1 MMP16 ENPEP

1.72e-071949375f5f0cdeacd5e1b28717d78dabdb9eb95f661e36
ToppCellPND07-28-samps-Mesenchymal|PND07-28-samps / Age Group, Lineage, Cell class and subclass

TRABD2B RYK FREM1 PTPRD HMCN1 PTPRS ENPEP

1.72e-0719493768bcc1fe8dc8d5f23a12154fc9b41362fdef0b1d
ToppCellPSB-critical-LOC-Epithelial-Basal|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

COL4A5 COL4A6 GAMT HMCN1 SULT2B1 PTPRS SULF1

2.05e-071999372add64c3e4cb6384ec381f34c3f1f77e13e3f27c
ToppCellCOPD-Myeloid-DC_Langerhans|World / Disease state, Lineage and Cell class

GPAT3 SEPTIN6 CD1A CD1E CLCNKB PAK1

1.09e-061609361b73a14ad6546d9f2812c19081278a79260abeae
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A3 COL4A6 USP24 HMCN1 CLCNKA CLCNKB

1.71e-061739360c74bdb40e635d906fd180412c23bf7fed61621e
ToppCellE18.5-samps-Mesenchymal-Matrix_fibroblast|E18.5-samps / Age Group, Lineage, Cell class and subclass

PLSCR4 TRABD2B FREM1 PTPRD PTPRS ENPEP

2.30e-06182936ceb37c214662a48efb56ab0d015977c6fab478b0
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRABD2B USP24 FREM1 HMCN1 CLCNKA CLCNKB

2.37e-061839362e831a4d99c6f983793df71c0994124c943c6da9
ToppCell10x_5'_v1-Non-neoplastic-Myeloid-Mono-Mono_naive-Z|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CES1 GPAT3 SIRPB1 MEFV ADGRE3 CDA

2.69e-061879363b1439018e265a61d9599e307a202e3c2f60ed32
ToppCell10x_5'_v1-Non-neoplastic-Myeloid-Mono-Mono_naive|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CES1 GPAT3 SIRPB1 MEFV ADGRE3 CDA

2.69e-06187936e99bc27d212c74da37770297122a4b30445ccd0d
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A3 USP24 FREM1 HMCN1 CLCNKA CLCNKB

2.77e-06188936bc089cd73d283ed7d2ecbb3936673b4edc89f666
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PLSCR4 CES1 NTRK3 PTPRS SULF1 PAK3

2.77e-06188936ce85a56ac27a6432421dde93a1bafa8b943244b9
ToppCellwk_08-11-Hematologic-Myeloid-Promonocyte-like|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

CYBB SIRPB1 MEFV CD1A CD1E CDA

2.77e-061889362ae945d96a011f246d04a42bcd6ef443232b03f4
ToppCellCOVID-19-kidney-DCT|kidney / Disease (COVID-19 only), tissue and cell type

COL4A3 COL4A5 TRABD2B USP24 HMCN1 CLCNKB

2.77e-06188936df1fd0819d301679f3c9ea404e942e39095912eb
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A3 COL4A5 GPR39 USP24 FREM1 HMCN1

2.86e-06189936975c0f079903ae36b0ffa54e86294d42ec7697de
ToppCellPND07-28-samps-Mesenchymal-Matrix_fibroblast|PND07-28-samps / Age Group, Lineage, Cell class and subclass

TRABD2B FREM1 PTPRD HMCN1 PTPRS ENPEP

2.86e-06189936dc5164591dea45b420798b94dda211be03daa70c
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CES1 ADGRB3 FREM1 PTPRD HMCN1 ENPEP

2.86e-06189936203c80030df08ae112f9ae4043709f455d87ce89
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A3 COL4A5 GPR39 USP24 FREM1 HMCN1

2.86e-061899367eb8f5a951e80f1cfac4d7c9eb169f4eb100c917
ToppCellPND07-28-samps-Mesenchymal-Matrix_fibroblast-FB-3|PND07-28-samps / Age Group, Lineage, Cell class and subclass

TRABD2B FREM1 PTPRD HMCN1 PTPRS ENPEP

2.94e-061909361196b8ea2c44c7c80f5ee589dd517e6a413f2077
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PLSCR4 CES1 NTRK3 PTPRS SULF1 PAK3

2.94e-06190936efb757f11c2809e66ddb48a5c84f5433f111cb7c
ToppCellwk_08-11-Hematologic-Myeloid-S100A12-hi_cla._mono.|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

CYBB SIRPB1 MEFV CD1A ADGRE3 CDA

2.94e-06190936b8c131020d20005cd9f23d26312196f62c958074
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL4A5 TRABD2B ROR1 PTPRS PAK3 ABTB2

3.03e-06191936b133ee1c0e58d00ddd2e4e05b01fd04947524c18
ToppCellMesenchymal-matrix_fibroblast_2_cell|World / Lineage, Cell type, age group and donor

PLSCR4 NTRK3 SULF1 PAK3 MMP16 ENPEP

3.13e-06192936a769158c49d2b208c4224d85e7ae68c85cc372ed
ToppCell10x5'v1-week_14-16-Myeloid_DC-DC-DC2|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

CES1 GPAT3 CD1A CD1E PAK1 NME2

3.32e-06194936a0cfc8c1cdc0722db39170e4417615b6e6b85041
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A5 GPR39 ROR1 FREM1 ABTB2 TMEM117

3.32e-061949364579b4a44f7c731553a284843c296866027d7c0e
ToppCellBronchial-NucSeq-Epithelial-Epi_alveolar-AT1|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

COL4A3 COL4A5 GPR39 ROR1 PTPRF SULT2B1

3.42e-06195936a71ba5e4043e2d35a45a2c60a96b087e31832345
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A5 GPR39 ROR1 FREM1 ABTB2 TMEM117

3.42e-061959363d6d3de8ada6dce3dc789c15b50cc066e7100496
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Macroglial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAG SLC6A9 PTPRD PAK1 CNTN2 TMEM117

3.52e-06196936f068ce40bf35021baf1468ae9ce30a92162eb14d
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

PLSCR4 ADGRB3 FREM1 PTPRD SULF1 ENPEP

3.52e-0619693622538376a95fe3afe8639a216a5497087aa94110
ToppCell(7)_Epithelial-I_(AT1)|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

COL4A3 KDM5A ROR1 PTPRF SULT2B1 MVB12B

3.52e-06196936150554fa06868d29b0608189862eef6505ba757f
ToppCellwk_15-18-Hematologic-Myeloid-S100A12-hi_cla._mono.|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

CYBB SIRPB1 MEFV ABHD5 ADGRE3 CDA

3.52e-06196936aa53ae1e5d08d31cfd81b7fae46c2b5d21d4f9b2
ToppCellCOVID-19-Fibroblasts-Intermediate_pathological_FB|COVID-19 / group, cell type (main and fine annotations)

PLSCR4 ROR1 ADGRB3 PTPRD HMCN1 SULF1

3.63e-06197936f1c8936986123a3151140c374fcd62d6705c530b
ToppCellwk_20-22-Hematologic-Myeloid-S100A12-hi_cla._mono.|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

CYBB SIRPB1 MEFV ABHD5 PAK1 CDA

3.63e-06197936e862561f61a1ae1ec858b34f8d9c9a7dc8894104
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Macroglial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAG SLC6A9 PTPRD PAK1 CNTN2 TMEM117

3.63e-061979367b12f9d4ad1e84df58e86591a491c84d4f36eac5
ToppCellCOVID-19-Fibroblasts|COVID-19 / group, cell type (main and fine annotations)

PLSCR4 ROR1 ADGRB3 HMCN1 PTPRS SULF1

3.63e-06197936fb847f2277609c31fffcdf49517243ce0684facf
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Macroglial-oligodendrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAG GAMT SLC6A9 PTPRD PAK1 CNTN2

3.73e-06198936a183afe4c2034323f77abfa080f359d67da35e8f
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Macroglial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAG SLC6A9 SLC6A11 PTPRD PAK1 CNTN2

3.73e-06198936731a90f7e68b19e387499d63e3979af78b503b0c
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Macroglial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAG SLC6A9 SLC6A11 PTPRD PAK1 CNTN2

3.73e-0619893643a2ce64fa309bac89a44ea320e87ae2cc39f782
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Macroglial-oligodendrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAG SLC6A9 PTPRD PAK1 CNTN2 TMEM117

3.73e-0619893697ae237f955fd5fbd01d06aafe89ef9e6f777a9a
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Macroglial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAG GAMT SLC6A9 PTPRD PAK1 CNTN2

3.73e-0619893627f0654fb0857e93f030e1a4b1c307b31576bbcd
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Macroglial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAG GAMT SLC6A9 PTPRD PAK1 CNTN2

3.73e-06198936fef9a4c96450078527b94d25e681410e4ea01b13
ToppCellPBMC-Mild-Myeloid|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

CYBB SIRPB1 MEFV LACTB PAK1 CDA

3.84e-0619993602256d86541be6851634283047fdc05fdf095114
ToppCellMesenchymal|World / Lineage, Cell type, age group and donor

PLSCR4 ADGRB3 FREM1 HMCN1 PTPRS ENPEP

3.84e-061999364bac110c2b3609f6ee5d0e3275da0824a6240270
ToppCellSigmoid-(5)_Dendritic_cell-(50)_cDC2|Sigmoid / shred on region, Cell_type, and subtype

GPAT3 DAO CD1A CD1E ADGRE3 PAK1

3.84e-06199936402af84db90d8a49d67cf44c24766aefb00fd716
ToppCellPBMC-Mild-Myeloid|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CYBB SIRPB1 MEFV LACTB PAK1 CDA

3.84e-0619993627667838e065370d4536eaaf5b42ad322a714b96
ToppCell10x5'v1-week_17-19-Myeloid_monocytic|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

CYBB CES1 GPAT3 SIRPB1 PAK1 CDA

3.84e-06199936aa30a57c0907d012942e7babdbff6ea4d01d7798
ToppCell10x5'v1-week_17-19-Myeloid_monocytic-monocyte|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

CYBB CES1 GPAT3 SIRPB1 PAK1 CDA

3.84e-061999367e5a56bb2ac441a8fa4ad0b928f9c0c82d128190
ToppCellCOVID-19_Mild-Myeloid|COVID-19_Mild / Disease group, lineage and cell class

CYBB SIRPB1 MEFV LACTB PAK1 CDA

3.84e-06199936d0c230c3699955a80630b63ed18c770444c5dfe5
ToppCellSigmoid-Dendritic_cell-cDC2|Sigmoid / Region, Cell class and subclass

GPAT3 DAO CD1A CD1E ADGRE3 PAK1

3.84e-06199936cd74db6db694b68f81dcf9d9342d125d00357ec1
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-1_mon-Proliferating-Cycling_Progenitors|1_mon / Sample Type, Dataset, Time_group, and Cell type.

COL4A5 COL4A6 POLR2A ROR1 RYK PTPRF

3.84e-06199936358c4b3037f59378db8916a2fbe9ed4830cf1449
ToppCell10x3'2.3-week_12-13-Myeloid_monocytic-monocyte-CD14_monocyte|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

CYBB CES1 GPAT3 MEFV PAK1 CDA

3.96e-062009364984d27b3768be3b8fca3391cd2b7ab1749e2913
ToppCellBronchial-NucSeq-Stromal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TRABD2B ADGRB3 FREM1 HMCN1 PTPRS SULF1

3.96e-06200936389cc775c8419d90fb77cd794376d2160a7bf44e
ToppCellBronchial-NucSeq-Stromal-Fibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ADGRB3 FREM1 HMCN1 PTPRS SULF1 ENPEP

3.96e-06200936cae972324d1dfea6efeaf6013f265c7c6bb48db4
ToppCellCOVID-19-COVID-19_Mild-Myeloid|COVID-19_Mild / Disease, condition lineage and cell class

CYBB SIRPB1 MEFV LACTB PAK1 CDA

3.96e-06200936247040492b3c327f4144fc94cf210dc04eecc7b0
ToppCell(09)_Ionocytes|World / shred by cell type and Timepoint

ROR1 CLCNKB KCNC4 SH3BGRL2 TMEM117

9.49e-06135935237b9b646513ca6e4b754c0da95d24015b3661f7
ToppCellPBMC-Severe-Myeloid-cDC-cDC-cDC_2|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

GPAT3 CD1E HMCN1 PAK1 GLIPR1L1

1.09e-051399354f4b447e85dda69058d9edbcfe37e55751dd90a6
ToppCellPBMC-Severe-Myeloid-cDC-cDC-cDC_2|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

GPAT3 CD1E HMCN1 PAK1 GLIPR1L1

1.09e-051399351cc48af58a2443db3c6798080b9c4bc70000cf87
ToppCellmetastatic_Brain-Myeloid_cells-CD1c+_DCs|Myeloid_cells / Location, Cell class and cell subclass

GPAT3 SEPTIN6 CD1A CD1E PAK1

1.21e-051429351eecbec805a873fa3539df0574670cf73c18c7b1
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Connecting_Tubule_Intercalated_Cell_Type_A|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FREM1 CLCNKA CLCNKB ABTB2 TMEM117

1.58e-0515093587968ce885a4959616f0321f58517fe8029ba1b1
ToppCell10x5'v1-week_12-13-Myeloid_DC-DC-DC2|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

MAG CES1 GPAT3 CD1E PAK1

1.91e-0515693503f3c5ffb27758fe63797143fcc938f9e8a4e10d
ToppCellCOPD-Myeloid-DC_Langerhans|COPD / Disease state, Lineage and Cell class

GPAT3 CD1A CD1E CLCNKB PAK1

2.03e-0515893571af1319eec34bf7bc9361ec9ef720c280ce97d1
ToppCellmetastatic_Brain-Myeloid_cells-CD1c+_DCs|metastatic_Brain / Location, Cell class and cell subclass

GPAT3 SEPTIN6 CD1A CD1E PAK1

2.09e-0515993535a63ca521635389a1edc7c81157793b8ad24d38
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Connecting_Tubule_Intercalated_Cell_Type_A|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MAG CLCNKB KCNC4 CDA TMEM117

2.16e-0516093586fde32f096eaf9ea3677f57169cdcc0a57bb8dd
ToppCellAT1-AT2_cells-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

COL4A3 COL4A5 ROR1 CLCNKB SULF1

2.29e-0516293557d627259d27f39885bf416d74bcb6656db6e27b
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_naive-D|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CES1 SIRPB1 MEFV CDA NME2

2.36e-051639354be3158f2a0ab460cfea8080a7370922910b5da9
ToppCellCOPD-Myeloid-DC_Langerhans|Myeloid / Disease state, Lineage and Cell class

GPAT3 CD1A CD1E CLCNKB PAK1

2.43e-05164935a07c6e13c07a90bc37db0915eb14931eb8309a1e
ToppCellInfluenza_Severe-pDC|World / Disease group and Cell class

ADGRB3 PTPRS CORO6 TTC39A ABTB2

2.57e-05166935bd25ce4c03c3d6cd9d986b9be1d355da52f0f2d7
ToppCellIonocyte-iono-1|World / Class top

CMTR1 ROR1 CLCNKB KCNC4 TMEM117

2.80e-051699354b68bcb4b5fc3cd2db23cd4edace7444aa2d605c
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A3 PTPRD SULF1 MMP16 ENPEP

3.05e-05172935381ae1c3c07d0a424f43455ec571653b192a946a
ToppCellChildren_(3_yrs)-Mesenchymal-myofibroblast_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

PLSCR4 COL4A5 COL4A6 TRABD2B ADGRB3

3.14e-051739351f16d47f5548e257e4b17f8070c5619780a9c5fd
ToppCellPND07-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL4A3 COL4A5 TNNI3K PTPRF ILDR1

3.14e-0517393545808cf69122c16b9d2b5ffa06d15392c55954b7
ToppCellPND07-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2-AT1/AT2_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL4A3 COL4A5 TNNI3K PTPRF ILDR1

3.14e-051739357fa9dbcb258c3ab974490063951620e2def03db1
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GPAT3 FREM1 CLCNKB TMEM117 MVB12B

3.22e-051749355f4436863a40f8bca46e2989bca66c02b6be88d4
ToppCellFetal_29-31_weeks-Mesenchymal-vascular_smooth_muscle_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

NTRK3 ADGRB3 HMCN1 KCNC4 ENPEP

3.22e-05174935015d3742d3d79a57413a333f00ef2d380a9848dd
ToppCellCOVID-19-kidney-Podocyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

COL4A3 COL4A5 PTPRD SULF1 ENPEP

3.31e-05175935a73e3a65fd5c1e09cb0c2dae20c1a7bfcae49223
ToppCellsystemic_lupus_erythematosus-flare-Myeloid-conventional_dendritic_cell-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

GPAT3 SLC6A9 CD1E HMCN1 PAK1

3.31e-05175935c58a1f02d1e559d3638fe1500e960e82a8a7187b
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FREM1 CLCNKB CDA TMEM117 MVB12B

3.40e-0517693525ebc8716aa44e44fce577701e3e82c6745a75ab
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MAG FREM1 CDA TMEM117 MVB12B

3.40e-051769356c7edf1cb38644500bce6c5a1dd90bbe17415cdb
ToppCell356C-Fibroblasts-Fibroblast-G|356C / Donor, Lineage, Cell class and subclass (all cells)

ADGRB3 PTPRD HMCN1 PTPRS ENPEP

3.50e-051779358220cc2fc0ee8764a67a3be51d75248be2453040
ToppCellBAL-Severe-cDC_3|Severe / Compartment, Disease Groups and Clusters

ADGRB3 GPAT3 CD1A CD1E PAK1

3.50e-05177935939487a05311b66edfc3f44a7955fbf25266d6bf
ToppCell356C-Fibroblasts-Fibroblast-G-|356C / Donor, Lineage, Cell class and subclass (all cells)

ADGRB3 PTPRD HMCN1 PTPRS ENPEP

3.50e-051779357617270f49cd6b7ba66db72d20560cee985012b2
ToppCellChildren_(3_yrs)-Epithelial-basal_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

COL4A5 COL4A6 GPR39 SULT2B1 SULF1

3.59e-05178935fba2e38c05cbf031e0c6d47b1602575fea734a57
ToppCellBronchial_Biopsy-Immune-Neutrophils|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X

CYBB SIRPB1 MEFV STK10 ADGRE3

3.69e-051799358c50e13927c09de05c86cd90dd6f71cee004b0d3
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A3 PTPRD SULF1 ENPEP SH3BGRL2

3.79e-05180935d685fa2b013bc085dbef7c40956ed3043f83e483
ToppCellnormal_Lymph_Node-Myeloid_cells-Pleural_Mac|normal_Lymph_Node / Location, Cell class and cell subclass

CYBB MEFV LACTB CD1E ABTB2

3.89e-05181935921e917f83105896ad8918dc134b871708024021
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A3 PTPRD SULF1 PAK1 ENPEP

3.89e-051819355bf7aa43f6e6ecce15c95928b91195544d6928c4
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

ADGRB3 FREM1 PTPRD HMCN1 ENPEP

3.89e-051819359ede19228ba5c0668a9c06c915510b95585216ef
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A3 PTPRD SULF1 PAK1 ENPEP

3.89e-051819358e751f5d7cd2d328ec0196d874e8a507e8c4e1a9
ToppCell10x5'v1-week_12-13-Myeloid_neutrophil-granulo-neutrophil-myelocyte|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

CYBB EPPK1 SIRPB1 CDA DLEC1

3.99e-0518293552eac2f892ea7f26731e0b21c578fd2665a1657a
ToppCellCOVID-19-kidney-CD-IC-B|COVID-19 / Disease (COVID-19 only), tissue and cell type

FREM1 CLCNKB CDA TMEM117 MVB12B

3.99e-05182935ee6a8c356bbbdae55e4ea858337e079491f9f4aa
ToppCellIPF-Myeloid-DC_Langerhans|World / Disease state, Lineage and Cell class

GPAT3 SEPTIN6 CD1A CD1E PAK1

3.99e-051829350e8cfbd8ea196f27a227dbb4d2eb93bc48d27922
ToppCellAdult-Mesenchymal-airway_smooth_muscle_cell-D175|Adult / Lineage, Cell type, age group and donor

NTRK3 SLC6A9 KLHL9 KCNC4 SULF1

3.99e-05182935ad4d74d8b19976e1ccc3c5ba8013199338cf6fd8
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TRABD2B ROR1 PTPRS PAK3 ABTB2

4.10e-051839357eae9b3b4d1c9b135fa7cff348393d4adec474b4
ToppCellCOVID-19-kidney-Podocyte|kidney / Disease (COVID-19 only), tissue and cell type

COL4A3 COL4A5 PTPRD SULF1 ENPEP

4.10e-05183935fb5e2a31b560126e1c04a386c24c365901c60ad7
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A3 COL4A5 PTPRD SULF1 ENPEP

4.10e-051839353c516fe5083f02bad1f464ed284010b4131a833c
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1-AT1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL4A3 CES1 GPR39 ROR1 PTPRF

4.10e-05183935274483009b309289e4cb84beedf6806430db6ff6
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A3 COL4A5 PTPRD SULF1 ENPEP

4.10e-051839359c2689d76fc6d30f5ab093428aa669d0a98953cf
ToppCellAT1-AT2_cells-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

COL4A3 COL4A5 ROR1 TNNI3K PTPRF

4.10e-051839356821dca076318115d360ff426eb1218cfe104063
ToppCellLPS_only-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL4A3 COL4A5 GPR39 ROR1 PTPRF

4.21e-0518493542ce855b4f8475a8298192feec785bdc69bc5bb0
Drugallo-threonine

DAO SLC1A4 STK10 PAK1 PAK2 PAK3

1.00e-05119946CID000000205
Drugmycobactin

CD1A CD1E ABHD5 SULT2B1

1.29e-0535944CID005748534
Drughaloperidol; Up 200; 10uM; MCF7; HT_HG-U133A

KDM5A SLC1A4 RYK SLC6A9 MMP16 ENPEP MAP3K2

1.35e-051899476960_UP
DrugTenoxicam [59804-37-4]; Up 200; 11.8uM; MCF7; HT_HG-U133A

COL4A3 AMPD1 SEPTIN6 CD1E ADGRE3 TTC39A MVB12B

1.60e-051949474182_UP
DrugHydroxytacrine maleate (R,S) [118909-22-1]; Up 200; 12.2uM; PC3; HT_HG-U133A

MAG SLC1A4 SLC6A9 PTPRD SULF1 MMP16 ENPEP

1.83e-051989476651_UP
Diseasemyopathy (implicated_via_orthology)

COL4A3 COL4A5 COL4A6 CLCNKA CLCNKB

4.07e-0748925DOID:423 (implicated_via_orthology)
Diseasecollagen disease (implicated_via_orthology)

COL4A3 COL4A5 COL4A6

6.32e-0612923DOID:854 (implicated_via_orthology)
DiseaseBartter disease type 4B

CLCNKA CLCNKB

9.62e-062922cv:C4310805
DiseaseLeiomyomatosis, esophageal and vulval, with nephropathy

COL4A5 COL4A6

9.62e-062922C1839884
DiseaseBARTTER SYNDROME, TYPE 4B

CLCNKA CLCNKB

9.62e-062922C2751312
DiseaseBARTTER SYNDROME, TYPE 4B, NEONATAL, WITH SENSORINEURAL DEAFNESS

CLCNKA CLCNKB

9.62e-062922C4310805
DiseaseBartter disease type 3 (implicated_via_orthology)

CLCNKA CLCNKB

9.62e-062922DOID:0110144 (implicated_via_orthology)
DiseaseBartter disease type 4b (is_implicated_in)

CLCNKA CLCNKB

9.62e-062922DOID:0110146 (is_implicated_in)
DiseaseBARTTER SYNDROME, TYPE 4B, NEONATAL, WITH SENSORINEURAL DEAFNESS

CLCNKA CLCNKB

9.62e-062922613090
DiseaseBartter disease (implicated_via_orthology)

CLCNKA CLCNKB

9.62e-062922DOID:445 (implicated_via_orthology)
DiseaseLeiomyoma, Epithelioid

COL4A5 COL4A6

9.62e-062922C0086533
DiseaseProteinuria

CYBB COL4A5 PAK1 PAK2

9.95e-0643924C0033687
DiseaseAlport syndrome (is_implicated_in)

COL4A3 COL4A5

2.88e-053922DOID:10983 (is_implicated_in)
DiseaseAlport syndrome

COL4A3 COL4A5

2.88e-053922cv:C1567741
DiseaseCollagen IV-related nephropathies

COL4A3 COL4A5

2.88e-053922cv:CN076135
DiseaseHematuria, Benign Familial

COL4A3 COL4A5

5.75e-054922C0241908
DiseaseAlport Syndrome

COL4A3 COL4A5

5.75e-054922C1567741
Diseaseazoospermia (implicated_via_orthology)

PTPRD PTPRF PTPRS

8.13e-0527923DOID:14227 (implicated_via_orthology)
Disease2'-O-methylcytidine measurement

CDA NUP188

9.56e-055922EFO_0800635
DiseaseAlport Syndrome, X-Linked

COL4A3 COL4A5

9.56e-055922C1567742
DiseaseAlport Syndrome, Autosomal Dominant

COL4A3 COL4A5

9.56e-055922C1567743
DiseaseAlport Syndrome, Autosomal Recessive

COL4A3 COL4A5

9.56e-055922C1567744
DiseaseSchizophrenia

PLSCR4 MAG NTRK3 HLA-E DAO SIRPB1 SBNO2 SLC6A9 SLC6A11 CSNK1E PAK2

9.58e-058839211C0036341
DiseaseBartter syndrome

CLCNKA CLCNKB

1.43e-046922cv:C0004775
Diseasesyndromic X-linked intellectual disability Najm type (implicated_via_orthology)

CSNK1D CSNK1E

2.00e-047922DOID:0060807 (implicated_via_orthology)
DiseaseQRS duration

CES1 FSCB CD1E PTPRD HMCN1 DLEC1

3.48e-04298926EFO_0005055
DiseaseColorectal Carcinoma

COL4A6 AMPD1 ACACA PTPRU TNNI3K PTPRD SULT2B1 PTPRS NME2

3.48e-04702929C0009402
Diseasenephrogenic diabetes insipidus (implicated_via_orthology)

CLCNKA CLCNKB

4.26e-0410922DOID:12387 (implicated_via_orthology)
DiseaseDental enamel hypoplasia

DHX37 PTPRD

6.22e-0412922EFO_1001304
DiseaseOpioid use measurement

PTPRD MVB12B

9.83e-0415922EFO_0009937
Diseasethird ventricle volume measurement

PTPRD ABTB2

9.83e-0415922EFO_0010335
Diseaseattention deficit hyperactivity disorder, Cannabis use

SLC6A9 PTPRF

1.42e-0318922EFO_0003888, EFO_0007585
DiseaseMalignant neoplasm of breast

ROR1 B3GALNT2 FSCB PTPRD CSNK1D PAK1 CDA DLEC1 ENPEP PRRC2A

1.90e-0310749210C0006142
Diseasebrain infarction, neuritic plaque measurement, Lewy body dementia, cerebral amyloid angiopathy, neurofibrillary tangles measurement

PTPRD ABTB2

2.13e-0322922EFO_0004277, EFO_0006790, EFO_0006792, EFO_0006797, EFO_0006798
DiseaseRenal glomerular disease

COL4A3 COL4A5

2.33e-0323922C0268731
DiseaseGlomerulopathy Assessment

COL4A3 COL4A5

2.33e-0323922C4521256

Protein segments in the cluster

PeptideGeneStartEntry
SMSWYTPMPIKKGSV

CATSPERG

166

Q6ZRH7
GWLIPMQLMSYPLSE

CES1

356

P23141
KSYWLSTTAPIPMMP

COL4A6

1541

Q14031
MVTPVTWMDNPIEVY

ERVK-18

1

O42043
YWLSTPALMPMNMAP

COL4A3

1521

Q01955
EDYLMSMVWKRTPAG

ADGRB3

516

O60242
IRMMYGVSPWGDSPI

ACACA

476

Q13085
PNMTWMIQVPRIYDV

AMPD1

451

P23109
PKDLTYRPMSDMGWG

ASH2L

586

Q9UBL3
SKMNPLWNTMVIGGY

PSMB4

146

P28070
VMMSIWPYLQKIDPT

MFSD8

56

Q8NHS3
QPGRGQIMKVDAPWM

DAO

196

P14920
KYMNSGPVVAMVWEG

NME2

66

P22392
TMVGTPYWMAPEVVT

PAK3

436

O75914
LMGPRRYMGLVVTTW

OR11A1

136

Q9GZK7
LAYIWMPTPDMSTEG

EPM2A

226

O95278
MVPRAPWMEQEGSEY

HLA-E

66

P13747
KWPLGAPMLAAIYAM

LRRTM2

6

O43300
GMPMEFYSIIWNPLT

GPR39

86

O43194
SVMYAPWKPTVNGTM

MAG

321

P20916
WMPPESIMYRKFTTE

NTRK3

736

Q16288
RTGYWTMMNIPPVEK

FSCB

136

Q5H9T9
PLQMVYKMPCGQWLP

KIAA2026

1061

Q5HYC2
LPGYLKPETMVMMWT

LACTB

431

P83111
SGFYPKPVWVMWMRG

CD1A

226

P06126
GKYPMPNQSVPITWM

PLSCR4

86

Q9NRQ2
YKMMQGGVGIPTIRW

CSNK1D

56

P48730
DPGMSTKMWNIAITY

FREM1

1801

Q5H8C1
PQMMGKPLYWGADRS

ILDR1

231

Q86SU0
TGMKSVTGTPYWMSP

MAP3K2

516

Q9Y2U5
PRMNEWSYVAKMSEP

KLHL9

421

Q9P2J3
MYDVTPPGVVMGLAW

LONP1

756

P36776
RRPPWSYEMSKEQLM

GNL1

131

P36915
TLSPENGYWVVIMMK

MEFV

681

O15553
VKEVMDTWTRQMGYP

ENPEP

531

Q07075
VDISGMKVPWLYVGM

KDM5A

461

P29375
ELNSMGIWYRMGRVP

MVB12B

181

Q9H7P6
MPAITWYKDGQPIMS

HMCN1

1576

Q96RW7
CVAVGSPMPYVKWMQ

PTPRS

266

Q13332
SPMPYVKWMQGAEDL

PTPRS

271

Q13332
TQGPKPEMVYDFWRM

PTPRU

961

Q92729
RSTMVGTPYWMAPEV

PAK1

421

Q13153
GTPYWMAPEVVTRKA

PAK1

426

Q13153
EQSKRSTMVGTPYWM

PAK2

396

Q13177
STMVGTPYWMAPEVV

PAK2

401

Q13177
NPNLATYMKPEMWGK

EIF3C

386

Q99613
YPKPVWVMWMRGEQE

CD1E

236

P15812
MVTPVTWMDNPIEVY

ERVK-24

1

P61566
MVTPVTWMDNPIEIY

ERVK-7

1

P61567
VWYMPPMTREEGEDA

GPAT3

366

Q53EU6
YWSQDISTMMPKPPI

FIG4

331

Q92562
VSMGIWMAAIGPKRY

B3GALNT2

441

Q8NCR0
PIKNWSPMRLQMYSG

BORA

326

Q6PGQ7
SYWLSTPEPMPMSMQ

COL4A5

1536

P29400
SPPATYRWKMNGTEM

CNTN2

66

Q02246
IMVWQIPDYTPMRNI

CORO6

106

Q6QEF8
MVTPVTWMDNPIEVY

ERVK-5

1

Q9HDB8
PPMTWKWIVGPMFLY

CYBB

266

P04839
ILGKPVMERWETPYM

GAMT

36

Q14353
GKVNPPAADMKYMIW

GLIPR1L1

46

Q6UWM5
RSYWTMLMGQQEPAK

DLEC1

1666

Q9Y238
MYMKGVSSVEVQWIP

DHX37

991

Q8IY37
KPMVILPYMNWGNLK

RYK

406

P34925
MGLYIVRTVNEPWTM

CMTR1

746

Q8N1G2
VGAPMPYVKWMMGAE

PTPRF

256

P10586
TCVAVGSPMPYVKWM

PTPRD

256

P23468
GSPMPYVKWMLGAED

PTPRD

261

P23468
AYRKQMRGMPTFPWD

SULT2B1

296

O00204
WPMPRMFSKAPITYV

SAXO1

281

Q8IYX7
KYMNSGPVVAMVWEG

NME2P1

51

O60361
MSIYQAMWKGVLRPG

EPPK1

4911

P58107
KSYRPSSMEPWMEPL

PRRC2A

1621

P48634
EPRNMIYMSRLGIWG

SBNO2

426

Q9Y2G9
KVWMTFPYGRMDPSS

VPS8

336

Q8N3P4
IGNKMMRARQYPWGT

SEPTIN6

246

Q14141
WTYPMRREMQEILPG

STYX

21

Q8WUJ0
APKRPMSAYMLWLNA

SSRP1

546

Q08945
MTIPYGWAKRPMLQR

ABHD5

266

Q8WTS1
PPLMEWMRVAITYAE

ABTB2

421

Q8N961
RLMKWIMFPVGYGVP

ADGRE3

461

Q9BY15
MREFGTNWPVYMTKP

CDA

106

P32320
WMLILATTIPMPAGY

CLCNKA

411

P51800
WMLILATTIPMPAGY

CLCNKB

411

P51801
IWRYMSRPVMSGPGL

CNIH1

86

O95406
IRWMPPEAIMYGKFS

ROR1

656

Q01973
MTSLIPVGPIMWFRG

SIRPB1

56

O00241
MKTMDPGYPKPITVW

MMP16

466

P51512
DYVKLMMPSWMTPAQ

TRABD2B

126

A6NFA1
MWYVPVGIMFLVGSK

SLC1A4

266

P43007
MSEEQRQWMYKNVPP

SH3BGRL2

41

Q9UJC5
LGMEPRYARPEWMIV

POLR2A

236

P24928
SFIGTPYWMAPEVVM

STK10

191

O94804
KQGMIPRRYVMPWKE

TEX43

41

Q6ZNM6
PSWPGVYRLSMSLME

NUP188

1391

Q5SRE5
VWRISPMFKGVGYGM

SLC6A9

171

P48067
AYPKAVTMMPLSPLW

SLC6A11

381

P48066
MKIELSMQPWNPGYS

RWDD2B

1

P57060
FPWMLNMEPYTVSGM

USP24

1906

Q9UPU5
VTDMMLQDKPYPDWG

TMEM117

171

Q9H0C3
MTKQPGNLRWMAPEV

TNNI3K

621

Q59H18
DKHWIMQYTGPMLPI

SULF1

256

Q8IWU6
ISLPVPALEMMYIWN

TTC39A

451

Q5SRH9
YKMMQGGVGIPSIKW

CSNK1E

56

P49674
DMYPKTWSGMLVGAL

KCNC4

441

Q03721