Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	modification-dependent protein binding	MBTD1 ANK2 ANK3 L3MBTL2 KMT2A SUZ12	1.54e-05	206	52	6	GO:0140030
GeneOntologyMolecularFunction	histone binding	MBTD1 L3MBTL2 NCAPD2 BAZ1B KMT2A SUZ12	6.30e-05	265	52	6	GO:0042393
GeneOntologyMolecularFunction	phosphorylation-dependent protein binding	ANK2 ANK3	2.95e-04	10	52	2	GO:0140031
GeneOntologyMolecularFunction	methylated histone binding	MBTD1 L3MBTL2 SUZ12	1.46e-03	86	52	3	GO:0035064
GeneOntologyMolecularFunction	methylation-dependent protein binding	MBTD1 L3MBTL2 SUZ12	1.56e-03	88	52	3	GO:0140034
GeneOntologyMolecularFunction	ankyrin binding	OBSCN PLEC	1.62e-03	23	52	2	GO:0030506
GeneOntologyMolecularFunction	cytoskeletal anchor activity	ANK2 ANK3	1.77e-03	24	52	2	GO:0008093
GeneOntologyBiologicalProcess	protein localization to M-band	ANK2 OBSCN	5.76e-06	2	50	2	GO:0036309
GeneOntologyCellularComponent	costamere	ANK2 ANK3 PLEC	2.42e-05	22	54	3	GO:0043034
GeneOntologyCellularComponent	Z disc	ANK2 ANK3 SPHKAP OBSCN PLEC	4.38e-05	151	54	5	GO:0030018
GeneOntologyCellularComponent	I band	ANK2 ANK3 SPHKAP OBSCN PLEC	6.87e-05	166	54	5	GO:0031674
GeneOntologyCellularComponent	sarcomere	ANK2 ANK3 SPHKAP OBSCN PLEC	4.53e-04	249	54	5	GO:0030017
GeneOntologyCellularComponent	myofibril	ANK2 ANK3 SPHKAP OBSCN PLEC	6.87e-04	273	54	5	GO:0030016
GeneOntologyCellularComponent	intercalated disc	ANK2 ANK3 OBSCN	7.25e-04	68	54	3	GO:0014704
GeneOntologyCellularComponent	COPII vesicle coat	SEC24A SEC24B	7.68e-04	16	54	2	GO:0030127
GeneOntologyCellularComponent	contractile muscle fiber	ANK2 ANK3 SPHKAP OBSCN PLEC	9.01e-04	290	54	5	GO:0043292
GeneOntologyCellularComponent	sarcolemma	ANK2 ANK3 OBSCN PLEC	1.47e-03	190	54	4	GO:0042383
GeneOntologyCellularComponent	cell-cell contact zone	ANK2 ANK3 OBSCN	1.85e-03	94	54	3	GO:0044291
GeneOntologyCellularComponent	SWI/SNF superfamily-type complex	BAZ1B GON4L SUZ12	1.96e-03	96	54	3	GO:0070603
Domain	Znf_FCS	MBTD1 L3MBTL2	7.56e-05	5	52	2	IPR012313
Domain	Sec23/24_helical_dom	SEC24A SEC24B	1.13e-04	6	52	2	IPR006900
Domain	Sec23_24_beta_S	SEC24A SEC24B	1.13e-04	6	52	2	IPR012990
Domain	zf-Sec23_Sec24	SEC24A SEC24B	1.13e-04	6	52	2	PF04810
Domain	Sec23_trunk	SEC24A SEC24B	1.13e-04	6	52	2	PF04811
Domain	Sec23_helical	SEC24A SEC24B	1.13e-04	6	52	2	PF04815
Domain	Sec23_BS	SEC24A SEC24B	1.13e-04	6	52	2	PF08033
Domain	ZF_FCS	MBTD1 L3MBTL2	1.13e-04	6	52	2	PS51024
Domain	Sec23/24_trunk_dom	SEC24A SEC24B	1.13e-04	6	52	2	IPR006896
Domain	Znf_Sec23_Sec24	SEC24A SEC24B	1.13e-04	6	52	2	IPR006895
Domain	MBT	MBTD1 L3MBTL2	2.70e-04	9	52	2	SM00561
Domain	ZU5	ANK2 ANK3	2.70e-04	9	52	2	SM00218
Domain	MBT	MBTD1 L3MBTL2	2.70e-04	9	52	2	PS51079
Domain	MBT	MBTD1 L3MBTL2	3.37e-04	10	52	2	PF02820
Domain	Mbt	MBTD1 L3MBTL2	3.37e-04	10	52	2	IPR004092
Domain	ZU5	ANK2 ANK3	3.37e-04	10	52	2	PS51145
Domain	ZU5	ANK2 ANK3	4.93e-04	12	52	2	PF00791
Domain	ZU5_dom	ANK2 ANK3	4.93e-04	12	52	2	IPR000906
Domain	Gelsolin	SEC24A SEC24B	6.77e-04	14	52	2	PF00626
Domain	NPIP	NPIPB15 NPIPB9	6.77e-04	14	52	2	IPR009443
Domain	Gelsolin-like_dom	SEC24A SEC24B	6.77e-04	14	52	2	IPR007123
Domain	PRAME_family	PRAMEF5 PRAMEF6	1.26e-03	19	52	2	IPR026271
Domain	ADF-H/Gelsolin-like_dom	SEC24A SEC24B	2.02e-03	24	52	2	IPR029006
Domain	-	SEC24A SEC24B	2.02e-03	24	52	2	3.40.20.10
Domain	DEATH	ANK2 ANK3	2.55e-03	27	52	2	SM00005
Domain	Death	ANK2 ANK3	3.80e-03	33	52	2	PF00531
Domain	Death_domain	ANK2 ANK3	5.01e-03	38	52	2	IPR000488
Domain	MYB_LIKE	GON4L MIDEAS	5.01e-03	38	52	2	PS50090
Domain	DEATH_DOMAIN	ANK2 ANK3	5.01e-03	38	52	2	PS50017
Domain	BROMODOMAIN_2	BAZ1B KMT2A	5.82e-03	41	52	2	PS50014
Domain	BROMO	BAZ1B KMT2A	6.10e-03	42	52	2	SM00297
Domain	Bromodomain	BAZ1B KMT2A	6.10e-03	42	52	2	IPR001487
Domain	-	BAZ1B KMT2A	6.10e-03	42	52	2	1.20.920.10
Pathway	REACTOME_ER_TO_GOLGI_ANTEROGRADE_TRANSPORT	ANK2 ANK3 DCTN5 SEC24A SEC24B	5.10e-05	156	37	5	M27097
Pathway	REACTOME_TRANSPORT_TO_THE_GOLGI_AND_SUBSEQUENT_MODIFICATION	ANK2 ANK3 DCTN5 SEC24A SEC24B	1.20e-04	187	37	5	M961
Pubmed	Human transcription factor protein interaction networks.	ASNSD1 MBTD1 NOP16 L3MBTL2 SEC24A RECQL5 SEC24B BAZ1B GON4L KMT2A BCOR LARP4 MIDEAS TRIB1 PRRC2B RPL19	5.34e-10	1429	56	16	35140242
Pubmed	RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.	POM121 ANK3 SEC24A SEC24B CCDC77 RNF43 PRRC2B	2.21e-07	263	56	7	34702444
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	MBTD1 PRAMEF5 PRR5L GALNT1 ANK3 OBSCN BAZ1B PLEC CCDC77 BCOR PRAMEF6	1.06e-06	1084	56	11	11544199
Pubmed	Interaction network of human early embryonic transcription factors.	MBTD1 L3MBTL2 BAZ1B KMT2A BCOR MIDEAS PRRC2B	1.52e-06	351	56	7	38297188
Pubmed	The ankyrin-B C-terminal domain determines activity of ankyrin-B/G chimeras in rescue of abnormal inositol 1,4,5-trisphosphate and ryanodine receptor distribution in ankyrin-B (-/-) neonatal cardiomyocytes.	ANK2 ANK3	2.55e-06	2	56	2	11781319
Pubmed	Structural basis of diverse membrane target recognitions by ankyrins.	ANK2 ANK3	2.55e-06	2	56	2	25383926
Pubmed	Serotonin 5-HT7 receptor is a biomarker poor prognostic factor and induces proliferation of triple-negative breast cancer cells through FOXM1.	FOXM1 HTR7	2.55e-06	2	56	2	36006564
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	ANK3 SEC24B NCAPD2 BAZ1B KMT2A BCOR MIDEAS PRRC2B	2.68e-06	549	56	8	38280479
Pubmed	The proximal proteome of 17 SARS-CoV-2 proteins links to disrupted antiviral signaling and host translation.	POM121 GALNT1 PMPCA NOP16 SEC24A SEC24B GLUL TRAPPC8 LARP4 PRRC2B	4.21e-06	1007	56	10	34597346
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	MBTD1 ZBED4 NOP16 L3MBTL2 RECQL5 BAZ1B KMT2A SUZ12 BCOR MIDEAS RPL19	5.79e-06	1294	56	11	30804502
Pubmed	Novel interactions of ankyrins-G at the costameres: the muscle-specific Obscurin/Titin-Binding-related Domain (OTBD) binds plectin and filamin C.	ANK3 PLEC	7.63e-06	3	56	2	21223964
Pubmed	Human ankyrins and their contribution to disease biology: An update.	ANK2 ANK3	7.63e-06	3	56	2	33410423
Pubmed	Obscurin targets ankyrin-B and protein phosphatase 2A to the cardiac M-line.	ANK2 OBSCN	7.63e-06	3	56	2	18782775
Pubmed	Binding of an ankyrin-1 isoform to obscurin suggests a molecular link between the sarcoplasmic reticulum and myofibrils in striated muscles.	ANK2 OBSCN	7.63e-06	3	56	2	12527750
Pubmed	The ammonium transporter RhBG: requirement of a tyrosine-based signal and ankyrin-G for basolateral targeting and membrane anchorage in polarized kidney epithelial cells.	ANK2 ANK3	7.63e-06	3	56	2	15611082
Pubmed	Ankyrin-dependent Na+ channel clustering prevents neuromuscular synapse fatigue.	ANK2 ANK3	7.63e-06	3	56	2	34289389
Pubmed	Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation.	POM121 SEC24A BAZ1B BCOR LARP4 MIDEAS PRRC2B	8.60e-06	457	56	7	32344865
Pubmed	The Polycomb complex PRC2 supports aberrant self-renewal in a mouse model of MLL-AF9;Nras(G12D) acute myeloid leukemia.	KMT2A SUZ12	1.52e-05	4	56	2	22469984
Pubmed	HIFI-α activation underlies a functional switch in the paradoxical role of Ezh2/PRC2 in breast cancer.	FOXM1 SUZ12	1.52e-05	4	56	2	27303043
Pubmed	The role of the C-terminal domain of PCSK9 and SEC24 isoforms in PCSK9 secretion.	SEC24A SEC24B	1.52e-05	4	56	2	32058034
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	NOP16 DCTN5 CNEP1R1 RECQL5 SEC24B NCAPD2 BAZ1B GON4L KMT2A SUZ12 BCOR	2.26e-05	1497	56	11	31527615
Pubmed	CK2-regulated schwannomin-interacting protein IQCJ-SCHIP-1 association with AnkG contributes to the maintenance of the axon initial segment.	ANK2 ANK3	2.54e-05	5	56	2	25950943
Pubmed	Glial ankyrins facilitate paranodal axoglial junction assembly.	ANK2 ANK3	2.54e-05	5	56	2	25362471
Pubmed	An ankyrin-based mechanism for functional organization of dystrophin and dystroglycan.	ANK2 ANK3	2.54e-05	5	56	2	19109891
Pubmed	Ptbp2 represses adult-specific splicing to regulate the generation of neuronal precursors in the embryonic brain.	ANK3 SPHKAP GLUL	3.47e-05	39	56	3	22802532
Pubmed	Sec24 proteins and sorting at the endoplasmic reticulum.	SEC24A SEC24B	3.80e-05	6	56	2	10075675
Pubmed	In vivo assembly of the axon initial segment in motor neurons.	ANK2 ANK3	3.80e-05	6	56	2	23728480
Pubmed	A family of mammalian proteins homologous to yeast Sec24p.	SEC24A SEC24B	3.80e-05	6	56	2	10329445
Pubmed	Prediction of the coding sequences of unidentified human genes. IV. The coding sequences of 40 new genes (KIAA0121-KIAA0160) deduced by analysis of cDNA clones from human cell line KG-1.	PMPCA NCAPD2 SUZ12	4.04e-05	41	56	3	8590280
Pubmed	Oncogenic ZMYND11-MBTD1 fusion protein anchors the NuA4/TIP60 histone acetyltransferase complex to the coding region of active genes.	MBTD1 L3MBTL2 KMT2A	4.34e-05	42	56	3	35705031
Pubmed	Selective export of human GPI-anchored proteins from the endoplasmic reticulum.	SEC24A SEC24B	5.32e-05	7	56	2	20427317
Pubmed	Analysis of the role of membrane polarity in polycystic kidney disease of transgenic SBM mice.	ANK2 ANK3	5.32e-05	7	56	2	7495297
Pubmed	Fine-tuning the stimulation of MLL1 methyltransferase activity by a histone H3-based peptide mimetic.	KMT2A SUZ12	5.32e-05	7	56	2	21135039
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	L3MBTL2 RECQL5 BAZ1B KMT2A SUZ12 BCOR MIDEAS	5.32e-05	608	56	7	36089195
Pubmed	WWP2 ubiquitylates RNA polymerase II for DNA-PK-dependent transcription arrest and repair at DNA breaks.	ASNSD1 NOP16 RECQL5 LARP4 MIDEAS PRRC2B RPL19	5.72e-05	615	56	7	31048545
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	CDR2L ZBED4 NCAPD2 OSBPL5 OBSCN PLEC TRIB1 RNF43 PRRC2B	6.32e-05	1105	56	9	35748872
Pubmed	Proteome analysis of the thalamus and cerebrospinal fluid reveals glycolysis dysfunction and potential biomarkers candidates for schizophrenia.	ANK2 GLUL PLEC	6.91e-05	49	56	3	20471030
Pubmed	Novel obscurins mediate cardiomyocyte adhesion and size via the PI3K/AKT/mTOR signaling pathway.	ANK3 OBSCN	7.09e-05	8	56	2	28826662
Pubmed	SEC24A deficiency lowers plasma cholesterol through reduced PCSK9 secretion.	SEC24A SEC24B	7.09e-05	8	56	2	23580231
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	NCAPD2 BAZ1B KMT2A PLEC LARP4 PRRC2B RPL19	8.32e-05	653	56	7	22586326
Pubmed	Hypertonicity-responsive ubiquitin ligase RNF183 promotes Na, K-ATPase lysosomal degradation through ubiquitination of its β1 subunit.	ANK2 SEC24A SEC24B NCAPD2 RNF43 RPL19	8.42e-05	449	56	6	31732153
Pubmed	ZBED4, a cone and Müller cell protein in human retina, has a different cellular expression in mouse.	ZBED4 GLUL	9.10e-05	9	56	2	21850176
Pubmed	Potent and specific Atg8-targeting autophagy inhibitory peptides from giant ankyrins.	ANK2 ANK3	9.10e-05	9	56	2	29867141
Pubmed	A direct physical interaction between Nanog and Sox2 regulates embryonic stem cell self-renewal.	MBTD1 L3MBTL2 BCOR MIDEAS	9.24e-05	146	56	4	23892456
Pubmed	RNF43 G659fs is an oncogenic colorectal cancer mutation and sensitizes tumor cells to PI3K/mTOR inhibition.	ASNSD1 OBSCN LARP4 RNF43	9.74e-05	148	56	4	35676246
Pubmed	The transport signal on Sec22 for packaging into COPII-coated vesicles is a conformational epitope.	SEC24A SEC24B	1.14e-04	10	56	2	17499046
Pubmed	Cell organization, growth, and neural and cardiac development require αII-spectrin.	ANK2 ANK3	1.14e-04	10	56	2	22159418
Pubmed	ESCs require PRC2 to direct the successful reprogramming of differentiated cells toward pluripotency.	KMT2A SUZ12	1.14e-04	10	56	2	20569692
Pubmed	Structural basis of cargo membrane protein discrimination by the human COPII coat machinery.	SEC24A SEC24B	1.14e-04	10	56	2	18843296
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	ANK2 L3MBTL2 SEC24B BAZ1B KMT2A BCOR PRRC2B RPL19	1.19e-04	934	56	8	33916271
Pubmed	Mouse screen reveals multiple new genes underlying mouse and human hearing loss.	MBTD1 PRAMEF5 L3MBTL2 DCTN5 SEC24A BAZ1B CCDC77 PRRC2B PRAMEF6	1.53e-04	1242	56	9	30973865
Pubmed	PRC1 and PRC2 are not required for targeting of H2A.Z to developmental genes in embryonic stem cells.	MBTD1 L3MBTL2 BCOR	1.61e-04	65	56	3	22496869
Pubmed	Planar cell polarity defects and defective Vangl2 trafficking in mutants for the COPII gene Sec24b.	SEC24A SEC24B	1.66e-04	12	56	2	20215345
Pubmed	CCL25 and CCL28 promote alpha4 beta7-integrin-dependent adhesion of lymphocytes to MAdCAM-1 under shear flow.	CCL28 CCR7	1.96e-04	13	56	2	18308860
Pubmed	The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.	ZBED4 L3MBTL2 BAZ1B PLEC PRRC2B	1.97e-04	332	56	5	37433992
Pubmed	Genomic analysis of mouse retinal development.	MBTD1 SPHKAP NCAPD2 GLUL KMT2A SUZ12 PLEC PRRC2B	1.98e-04	1006	56	8	15226823
Pubmed	MYC Protein Interactome Profiling Reveals Functionally Distinct Regions that Cooperate to Drive Tumorigenesis.	FOXM1 MBTD1 L3MBTL2 KMT2A BCOR	2.17e-04	339	56	5	30415952
Pubmed	MLL-AF9 and MLL-ENL alter the dynamic association of transcriptional regulators with genes critical for leukemia.	KMT2A BCOR	2.29e-04	14	56	2	20854876
Pubmed	Analysis of gene expression in the developing mouse retina.	GLUL PLEC	2.29e-04	14	56	2	12702772
Pubmed	Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.	FOXM1 ASNSD1 MBTD1 ZBED4 CNEP1R1 RECQL5 GLUL KMT2A SUZ12	2.51e-04	1327	56	9	32694731
Pubmed	Ankyrin-G regulated epithelial phenotype is required for mouse lens morphogenesis and growth.	ANK2 ANK3	2.64e-04	15	56	2	30562487
Pubmed	In vitro nuclear interactome of the HIV-1 Tat protein.	NCAPD2 BAZ1B KMT2A SUZ12	2.80e-04	195	56	4	19454010
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	L3MBTL2 RECQL5 SEC24B NCAPD2 BAZ1B PLEC LARP4 MIDEAS RPL19	2.89e-04	1353	56	9	29467282
Pubmed	HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.	ASNSD1 ANK2 NOP16 KMT2A PLEC CCDC77 LARP4 MIDEAS PRRC2B	3.19e-04	1371	56	9	36244648
Pubmed	Differential expression of PRAMEL1, a cancer/testis antigen, during spermatogenesis in the mouse.	PRAMEF5 PRAMEF6	3.41e-04	17	56	2	23565261
Pubmed	Mouse Pramel1 regulates spermatogonial development by inhibiting retinoic acid signaling during spermatogenesis.	PRAMEF5 PRAMEF6	3.41e-04	17	56	2	37781892
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	FOXM1 MBTD1 RECQL5 BAZ1B BCOR PRRC2B	3.61e-04	588	56	6	38580884
Pubmed	Phosphoproteome analysis of the human mitotic spindle.	NCAPD2 BAZ1B KMT2A PLEC	3.71e-04	210	56	4	16565220
Pubmed	Oocyte-specific gene Oog1 suppresses the expression of spermatogenesis-specific genes in oocytes.	PRAMEF5 PRAMEF6	3.83e-04	18	56	2	29731491
Pubmed	The promoter of the oocyte-specific gene, Oog1, functions in both male and female meiotic germ cells in transgenic mice.	PRAMEF5 PRAMEF6	3.83e-04	18	56	2	23894331
Pubmed	Identification of a new expanding family of genes characterized by atypical LRR domains. Localization of a cluster preferentially expressed in oocyte.	PRAMEF5 PRAMEF6	3.83e-04	18	56	2	14675769
Pubmed	Kv7/KCNQ potassium channels in cortical hyperexcitability and juvenile seizure-related death in Ank2-mutant mice.	ANK2 ANK3	3.83e-04	18	56	2	37321992
Pubmed	Ecm29-mediated proteasomal distribution modulates excitatory GABA responses in the developing brain.	ANK2 ANK3	3.83e-04	18	56	2	31910261
Pubmed	Oogenesin is a novel mouse protein expressed in oocytes and early cleavage-stage embryos.	PRAMEF5 PRAMEF6	3.83e-04	18	56	2	12890732
Pubmed	Pramel15 facilitates zygotic nuclear DNMT1 degradation and DNA demethylation.	PRAMEF5 PRAMEF6	3.83e-04	18	56	2	39181896
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	L3MBTL2 SEC24A SEC24B PLEC CCDC77 PRRC2B RPL19	4.25e-04	853	56	7	28718761
Pubmed	Pramel7 mediates ground-state pluripotency through proteasomal-epigenetic combined pathways.	PRAMEF5 PRAMEF6	4.28e-04	19	56	2	28604677
Pubmed	A polygenic basis for four classical Fredrickson hyperlipoproteinemia phenotypes that are characterized by hypertriglyceridemia.	BAZ1B TRIB1	4.28e-04	19	56	2	19656773
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	ANK2 ZBED4 PMPCA NCAPD2 KMT2A PLEC CCDC77 PRRC2B RPL19	4.61e-04	1442	56	9	35575683
Pubmed	The ULK1-FBXW5-SEC23B nexus controls autophagy.	SEC24A SEC24B	4.75e-04	20	56	2	30596474
Pubmed	Preferentially Expressed Antigen in Melanoma (PRAME) and the PRAME Family of Leucine-Rich Repeat Proteins.	PRAMEF5 PRAMEF6	4.75e-04	20	56	2	26694250
Pubmed	Oog1, an oocyte-specific protein, interacts with Ras and Ras-signaling proteins during early embryogenesis.	PRAMEF5 PRAMEF6	4.75e-04	20	56	2	16580637
Pubmed	Pramel7 mediates LIF/STAT3-dependent self-renewal in embryonic stem cells.	PRAMEF5 PRAMEF6	4.75e-04	20	56	2	21425410
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	ZBED4 SPHKAP GON4L SUZ12 PRRC2B	5.01e-04	407	56	5	12693553
Pubmed	EEF1D Promotes Glioma Proliferation, Migration, and Invasion through EMT and PI3K/Akt Pathway.	PLEC PRRC2B	5.24e-04	21	56	2	33029523
Pubmed	The RSPO-LGR4/5-ZNRF3/RNF43 module controls liver zonation and size.	GLUL RNF43	5.24e-04	21	56	2	27088858
Pubmed	USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.	CDR2L GON4L PLEC BCOR	5.58e-04	234	56	4	36243803
Pubmed	Sertoli cell-only phenotype and scRNA-seq define PRAMEF12 as a factor essential for spermatogenesis in mice.	PRAMEF5 PRAMEF6	5.76e-04	22	56	2	31729367
Pubmed	Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.	FOXM1 RECQL5 GON4L KMT2A SUZ12 CCDC77	5.87e-04	645	56	6	25281560
Pubmed	Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	OBSCN GON4L BCOR	5.89e-04	101	56	3	10997877
Pubmed	NuRD subunit CHD4 regulates super-enhancer accessibility in rhabdomyosarcoma and represents a general tumor dependency.	BAZ1B KMT2A TRAPPC8	6.24e-04	103	56	3	32744500
Pubmed	The proteomic reactor facilitates the analysis of affinity-purified proteins by mass spectrometry: application for identifying ubiquitinated proteins in human cells.	KMT2A PRRC2B	6.30e-04	23	56	2	17203973
Pubmed	Cytokinesis involves a nontranscriptional function of the Hippo pathway effector YAP.	PLEC ARHGAP45	6.30e-04	23	56	2	26933062
Pubmed	Oogenesis specific genes (Nobox, Oct4, Bmp15, Gdf9, Oogenesin1 and Oogenesin2) are differentially expressed during natural and gonadotropin-induced mouse follicular development.	PRAMEF5 PRAMEF6	6.30e-04	23	56	2	19480014
Pubmed	CATACOMB: An endogenous inducible gene that antagonizes H3K27 methylation activity of Polycomb repressive complex 2 via an H3K27M-like mechanism.	MBTD1 SUZ12	6.30e-04	23	56	2	31281901
Pubmed	BCOR modulates transcriptional activity of a subset of glucocorticoid receptor target genes involved in cell growth and mobility.	BCOR PRRC2B	6.87e-04	24	56	2	33722704
Pubmed	Human Antiviral Protein IFIX Suppresses Viral Gene Expression during Herpes Simplex Virus 1 (HSV-1) Infection and Is Counteracted by Virus-induced Proteasomal Degradation.	NOP16 BAZ1B PRRC2B RPL19	7.25e-04	251	56	4	28077445
Pubmed	Identification of proximal SUMO-dependent interactors using SUMO-ID.	FOXM1 SEC24B BAZ1B BCOR LARP4	7.42e-04	444	56	5	34795231
Pubmed	MAGE-B4, a binding partner of PRAMEF12, is dispensable for spermatogenesis and male fertility in mice.	PRAMEF5 PRAMEF6	7.46e-04	25	56	2	37451217
Pubmed	Incomplete reactivation of Oct4-related genes in mouse embryos cloned from somatic nuclei.	PRAMEF5 PRAMEF6	7.46e-04	25	56	2	12620990
Interaction	RNF43 interactions	ASNSD1 POM121 ANK3 SEC24A SEC24B OBSCN CCDC77 LARP4 RNF43 PRRC2B	1.42e-07	427	53	10	int:RNF43
Interaction	KLF16 interactions	MBTD1 NOP16 L3MBTL2 RECQL5 BAZ1B GON4L BCOR PRRC2B	1.41e-05	425	53	8	int:KLF16
Interaction	H2BC8 interactions	FOXM1 MBTD1 RECQL5 BAZ1B GON4L KMT2A SUZ12 BCOR MIDEAS	1.73e-05	576	53	9	int:H2BC8
Interaction	EYA4 interactions	SEC24B GLUL PLEC BCOR MIDEAS PRRC2B	4.13e-05	243	53	6	int:EYA4
Cytoband	18q12.1	GALNT1 TRAPPC8	4.66e-04	26	56	2	18q12.1
Cytoband	1p36.21	PRAMEF5 PRAMEF6	2.72e-03	63	56	2	1p36.21
Cytoband	Ensembl 112 genes in cytogenetic band chr11p13	PRR5L PAMR1	2.89e-03	65	56	2	chr11p13
GeneFamily	Sterile alpha motif domain containing\|MBT domain containing	MBTD1 L3MBTL2	1.30e-04	9	35	2	1263
GeneFamily	PRAME family	PRAMEF5 PRAMEF6	9.78e-04	24	35	2	686
GeneFamily	Rho GTPase activating proteins\|BCH domain containing	ARHGAP28 ARHGAP45	4.21e-03	50	35	2	721
GeneFamily	GATA zinc finger domain containing\|Myb/SANT domain containing	GON4L MIDEAS	4.72e-03	53	35	2	532
GeneFamily	Ankyrin repeat domain containing	ANK2 ANK3 BCOR	1.13e-02	242	35	3	403
GeneFamily	PHD finger proteins	BAZ1B KMT2A	1.31e-02	90	35	2	88
Coexpression	MARTORIATI_MDM4_TARGETS_FETAL_LIVER_DN	FOXM1 PRAMEF5 GALNT1 PMPCA SPHKAP SEC24B BAZ1B SUZ12 PRAMEF6	1.79e-06	543	55	9	MM997
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ANK3 HTR7 OBSCN KMT2A CCR7	3.49e-06	184	56	5	5350b58aa9979631228835d11eb45ddf81d08bff
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM1_(8)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	SPHKAP ARHGAP28 OCA2 RNF43 RPL19	4.41e-06	193	56	5	e2b455387d1de7812305200a2041a0f4759a6f54
ToppCell	10x5'-Lung-Myeloid_Monocytic-Cycling_mono\|Lung / Manually curated celltypes from each tissue	FOXM1 HTR7 NCAPD2 RNF43	4.44e-05	156	56	4	63b8cf14361b282872bc1c5b65d9fbc83e81a089
ToppCell	343B-Myeloid-Macrophage-SPP1+_Macrophage\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	CDR2L HTR7 CNEP1R1 RNF43	4.55e-05	157	56	4	4183dbed6b31ebe13ef33eb19ba6d0fb4f625953
ToppCell	367C-Lymphocytic-NK_cells-NK_cell_B\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	PRR5L OSBPL5 OCA2 FCRL6	4.66e-05	158	56	4	1bf692f1e85f677cd62805437b7a59cfaf3b0449
ToppCell	5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-CD8-positive,_alpha-beta_T_cell-CD8_T_cells-CD8_T_cells_L.1.1.2.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ARHGAP28 CCDC77 LARP4 FCRL6	5.39e-05	164	56	4	30c3c25b05a403a509b2e755c2f0878fecb10a02
ToppCell	Striatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Excitatory_Neuron.Gad1Gad2.Sgol2a_(Very_small_cluster)\|Striatum / BrainAtlas - Mouse McCarroll V32	POM121 CNEP1R1 MIDEAS FAM135B	6.06e-05	169	56	4	c3bf0cb67f200d02d5a021754e9b2a68d23ea168
ToppCell	droplet-Lung-nan-3m-Lymphocytic-CD4-positive,_alpha-beta_T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CCR7 ABHD8 ARHGAP45 RPL19	6.06e-05	169	56	4	81bbdcf1fdf5cad5bfe7a559af196ad0d8e18c35
ToppCell	Striatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Excitatory_Neuron.Gad1Gad2.Sgol2a_(Very_small_cluster)--\|Striatum / BrainAtlas - Mouse McCarroll V32	POM121 CNEP1R1 MIDEAS FAM135B	6.06e-05	169	56	4	5375eb52ebadccb7bfff997a11985f23e81014d6
ToppCell	Striatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Excitatory_Neuron.Gad1Gad2.Sgol2a_(Very_small_cluster)-\|Striatum / BrainAtlas - Mouse McCarroll V32	POM121 CNEP1R1 MIDEAS FAM135B	6.06e-05	169	56	4	1c132d21255f5a5174ac38db4e91927f9093418e
ToppCell	droplet-Lung-nan-3m-Lymphocytic-CD4+_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CCR7 ABHD8 ARHGAP45 RPL19	6.06e-05	169	56	4	b7db33be24a6a9386e277c2f8949551e4d259305
ToppCell	T_cells-GNLY+GZMB+_T_cells\|T_cells / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	PRR5L OSBPL5 OCA2 FCRL6	6.34e-05	171	56	4	04c811817cfec45af5f2891793106cc7ddb0300e
ToppCell	droplet-Limb_Muscle-nan-18m-Lymphocytic\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGAP45 RNF43 FCRL6 RPL19	6.49e-05	172	56	4	a3bcf0d432d8fccce50248e8d0c7a4804d69bfee
ToppCell	droplet-Limb_Muscle-nan-18m-Lymphocytic-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGAP45 RNF43 FCRL6 RPL19	6.49e-05	172	56	4	976d27edd5608616830624907fe050fcd3551865
ToppCell	droplet-Kidney-KIDNEY-1m-Lymphocytic\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CCR7 ARHGAP45 FCRL6 RPL19	6.49e-05	172	56	4	adf016e5856bc85e7bed58aee09ade483b9dcb00
ToppCell	5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ANK3 NPIPB9 RNF43 TMEFF2	6.78e-05	174	56	4	42f2ba54b4ea4c62482582b0ccdadffae0a5eb4a
ToppCell	5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)-Club_(non-nasal)_L.0.4.0.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ANK3 NPIPB9 SUZ12 TMEFF2	6.78e-05	174	56	4	3f0a5ce074675d57d479fa069385a1b3071e884e
ToppCell	droplet-Lung-LUNG-1m-Lymphocytic-CD8+_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CCR7 ABHD8 ARHGAP45 RPL19	7.09e-05	176	56	4	4478b3284201220e902bd2077960dc0d4d4a2c7c
ToppCell	droplet-Lung-LUNG-1m-Lymphocytic-CD8-positive,_alpha-beta_T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CCR7 ABHD8 ARHGAP45 RPL19	7.09e-05	176	56	4	828ca4d55d726f82f90293c3c7eba081ea3ab92e
ToppCell	droplet-Lung-LUNG-1m-Lymphocytic-CD4+_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CCR7 ABHD8 ARHGAP45 RPL19	7.41e-05	178	56	4	cd0c5f15e6b28ce2208346279ee9503d18d9b27d
ToppCell	droplet-Lung-LUNG-1m-Lymphocytic-CD4-positive,_alpha-beta_T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CCR7 ABHD8 ARHGAP45 RPL19	7.41e-05	178	56	4	813d121a45e0416de1f26862851f6f0bda7ba43c
ToppCell	COVID-19_Convalescent-PLT_1\|World / Disease Group and Platelet Clusters	POM121 ZBED4 SEC24B CCR7	7.57e-05	179	56	4	d0f2764c6fc5d61fd69e9231b3603a80ac373f65
ToppCell	droplet-Lung-LUNG-30m-Lymphocytic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CCR7 ABHD8 ARHGAP45 RPL19	8.60e-05	185	56	4	c9ab7a3584d25f0ed73b20919c3dba00f502eac4
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Epithelial-neuro-epithelial-EECs\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	POM121 ABHD8 RNF43 FAM135B	8.60e-05	185	56	4	d42f6722a6771752cd744146a09e2ead9b7252bc
ToppCell	LV-15._Ventricular_Cardiomyocyte_III\|World / Chamber and Cluster_Paper	ANK2 ANK3 SPHKAP OBSCN	8.60e-05	185	56	4	6baccb26f999145e51b91d94315bf8d4655bef31
ToppCell	droplet-Spleen-nan-3m-Lymphocytic-T_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CCR7 ABHD8 ARHGAP45 RPL19	8.96e-05	187	56	4	1387981d224cb9e846ed18e366736855a4eb827e
ToppCell	RV-04._Ventricular_Cardiomyocyte_I\|RV / Chamber and Cluster_Paper	ANK2 ANK3 SPHKAP OBSCN	9.34e-05	189	56	4	9c1debd65c13d63fd4f3158917d621b44b714c26
ToppCell	RV-15._Ventricular_Cardiomyocyte_III\|RV / Chamber and Cluster_Paper	ANK2 ANK3 OBSCN TMEFF2	9.53e-05	190	56	4	93c3188dfeb0b2f9889f8ae9b9c1f2f34129c99b
ToppCell	pdx-Tumor_cells-T1\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	FOXM1 NCAPD2 SUZ12 CCDC77	9.53e-05	190	56	4	d06ee5f89f1cec8db6897fe3b2a890a07cd3697b
ToppCell	RV-06._Ventricular_Cardiomyocyte_II\|RV / Chamber and Cluster_Paper	ANK2 ANK3 SPHKAP OBSCN	9.53e-05	190	56	4	fe8e78922c8ae928ef9a80bffd67868d5a87a091
ToppCell	LV-06._Ventricular_Cardiomyocyte_II\|LV / Chamber and Cluster_Paper	ANK2 ANK3 SPHKAP OBSCN	9.73e-05	191	56	4	25f3eb34f4e70761e81e84c8a5829f216108cbc6
ToppCell	LA-03._Atrial_Cardiomyocyte\|LA / Chamber and Cluster_Paper	ANK2 ANK3 SPHKAP OBSCN	9.73e-05	191	56	4	5d1b674eb7703830b7ce8bbeac3363cabd0e6ae9
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ANK3 CCR7 LRRC75A RPL19	9.73e-05	191	56	4	fda432a7f79664e8ffd5d03c1c69ec43bbac994b
ToppCell	LV-04._Ventricular_Cardiomyocyte_I\|LV / Chamber and Cluster_Paper	ANK2 ANK3 SPHKAP OBSCN	9.92e-05	192	56	4	ad19e2c1d36a0566c9b12ced10db78f4781c8ea6
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c05-FOS\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ANK3 CCR7 LRRC75A RPL19	9.92e-05	192	56	4	78546a6e077076834fd717607610ab6df3b6e7ba
ToppCell	3'_v3-Lung-Lymphocytic_T_CD4\|Lung / Manually curated celltypes from each tissue	ANK3 KMT2A CCR7 RPL19	9.92e-05	192	56	4	fd19cd0b5330448bef8debd753285adbc8b958a2
ToppCell	lymphoid-NK_cell-NK_cell\|World / Lineage, cell class and subclass	PRR5L OSBPL5 RNF43 FCRL6	1.03e-04	194	56	4	7f5adc18e632109694446b8eb1543cbae62dccbe
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM1_(8)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	ARHGAP28 OCA2 RNF43 RPL19	1.03e-04	194	56	4	fb80a0271ccb1cb3f954ebcf2c5945cb6adb6b8c
ToppCell	COVID-19-Heart-CM_1\|Heart / Disease (COVID-19 only), tissue and cell type	ANK2 ANK3 SPHKAP OBSCN	1.05e-04	195	56	4	f1ef50331eda8f1239dba6ea970df4eaccf032f1
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ANK3 CCR7 LRRC75A RPL19	1.05e-04	195	56	4	497d4bfbc38bcafab37e8a9c20bc9141f2e78d2a
ToppCell	COVID_non-vent-Lymphocytic-T_cell\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	ANK3 OBSCN KMT2A CCR7	1.05e-04	195	56	4	4bdedd924564a260841a9153604026b57487c83d
ToppCell	COVID-19-Heart-CM_2\|Heart / Disease (COVID-19 only), tissue and cell type	ANK2 ANK3 SPHKAP OBSCN	1.05e-04	195	56	4	75fc81bddb246dca3b437fb60827b1d4fe416405
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c05-FOS\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ANK3 CCR7 LRRC75A RPL19	1.05e-04	195	56	4	9c71d2a58e772b556e22e2f1d60593580b7aafd8
ToppCell	Control_saline-Epithelial_alveolar-AT_2-Differentiating_AT2\|Control_saline / Treatment groups by lineage, cell group, cell type	ANK3 SPHKAP TRIB1 RNF43	1.10e-04	197	56	4	44a59dfb889577b3160a5b13ada1276771a00241
ToppCell	medial-Hematologic-Myeloid_Dendritic_Type_1\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	HTR7 CCR7 ARHGAP45 FAM135B	1.10e-04	197	56	4	5bd2f32137fd849931e52093d630d2e7e27daf4f
ToppCell	medial-Hematologic-Myeloid_Dendritic_Type_1-2\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	HTR7 CCR7 ARHGAP45 FAM135B	1.10e-04	197	56	4	d9baa0be469fd8737a74b5078d30ce7d66759160
ToppCell	medial-2-Hematologic-Myeloid_Dendritic_Type_1\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	HTR7 CCR7 ARHGAP45 FAM135B	1.10e-04	197	56	4	3c1147857de6a7ab6b0cf77f5a6364d4c8669693
ToppCell	healthy_donor-Lymphocytic-T_cell\|healthy_donor / Disease condition, Lineage, Cell class and subclass	OBSCN KMT2A CCR7 RPL19	1.10e-04	197	56	4	63d0f06e150e7eb800ecb70e97b9d12a01c84e37
ToppCell	droplet-Limb_Muscle-nan-24m-Mesenchymal-skeletal_muscle_satellite_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANK3 GLUL TRIB1 RPL19	1.12e-04	198	56	4	d5e91d1057e71b6a336eec95e44b2e7fe6b2c6ef
ToppCell	Control_saline-Hematopoietic_Lymphocytic-Lymphocytic_NK/T\|Control_saline / Treatment groups by lineage, cell group, cell type	SEC24B CCR7 ARHGAP45 RPL19	1.12e-04	198	56	4	9663cf0c8296d3a7b0329cb725ccceeea7849cbc
ToppCell	Control_saline-Hematopoietic_Lymphocytic-Lymphocytic_NK/T-T-cells\|Control_saline / Treatment groups by lineage, cell group, cell type	SEC24B CCR7 ARHGAP45 RPL19	1.12e-04	198	56	4	42c855e313d574ef37c2353e4d69809146c391ff
ToppCell	LPS_IL1RA-Hematopoietic_Lymphocytic-Lymphocytic_NK/T-T-cells\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	SEC24B CCR7 ARHGAP45 RPL19	1.14e-04	199	56	4	9382abe4ca553bc4db12e413be921b626e56f2ac
ToppCell	distal-2-Hematologic-Natural_Killer\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	PRR5L OSBPL5 ARHGAP45 FCRL6	1.14e-04	199	56	4	77cc79c612c56022b37c8f690363c9ac8776e9cf
ToppCell	medial-Hematologic-Natural_Killer\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	PRR5L OSBPL5 ARHGAP45 FCRL6	1.14e-04	199	56	4	4a75ef6a3b7b5d779a08d039a79322cd60b4ef65
ToppCell	LPS_anti-TNF-Hematopoietic_Lymphocytic-Lymphocytic_NK/T-T-cells\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	SEC24B CCR7 ARHGAP45 RPL19	1.14e-04	199	56	4	618dc6425bb7b84d3b2de7cf8ecb41549a255718
ToppCell	medial-2-Hematologic-Natural_Killer\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	PRR5L OSBPL5 ARHGAP45 FCRL6	1.14e-04	199	56	4	52338b8970fba0b32578748ba0bec0b344171ca6
ToppCell	LPS_only-Hematopoietic_Lymphocytic-Lymphocytic_NK/T-T-cells\|LPS_only / Treatment groups by lineage, cell group, cell type	SEC24B CCR7 ARHGAP45 RPL19	1.14e-04	199	56	4	bd7f03bef4660c347da5f16db34d91d563908448
ToppCell	LPS_IL1RA_TNF-Hematopoietic_Lymphocytic-Lymphocytic_NK/T-T-cells\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	SEC24B CCR7 ARHGAP45 RPL19	1.14e-04	199	56	4	46e2d2962cd5b0f76baf976c0f6ecce117827274
ToppCell	medial-Hematologic-Natural_Killer-2\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	PRR5L OSBPL5 ARHGAP45 FCRL6	1.14e-04	199	56	4	dfcc4976688c7e6df5e41ae77436710075f1f779
ToppCell	COVID_vent-Lymphocytic-T_cell-CD4+_Naive_T_cell\|COVID_vent / Disease condition, Lineage, Cell class and subclass	ANK3 OBSCN CCR7 RPL19	1.14e-04	199	56	4	885bc902b6e2af0b61e452c4154160cd3f1cf98e
ToppCell	LPS_IL1RA_TNF-Hematopoietic_Lymphocytic\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	SEC24B CCR7 ARHGAP45 RPL19	1.14e-04	199	56	4	5611b9e405a685a7a099d2f2d21dee3a939c2911
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW26\|fetalBrain_Zhong_nature / Sample Type, Dataset, Time_group, and Cell type.	ANK2 OBSCN PLEC TMEFF2	1.16e-04	200	56	4	61d7dd0a78942b069c3f5e75044368dc00e6e8e6
ToppCell	Sepsis-Int-URO-Lymphocyte-T/NK-CD4+_T_naive\|Int-URO / Disease, condition lineage and cell class	CCL28 ANK3 CCR7 RPL19	1.16e-04	200	56	4	a4b531355e87efd6b69a16eeec8b1ff14c7af750
ToppCell	Bronchial-NucSeq-Immune_Lymphocytic-NK-ILC-T_NK\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PRR5L OSBPL5 FCRL6 RPL19	1.16e-04	200	56	4	7eed3d932018d6a87ce37d013883b371db55caeb
ToppCell	healthy_donor\|World / Disease condition, Lineage, Cell class and subclass	PRR5L OSBPL5 ARHGAP45 FCRL6	1.16e-04	200	56	4	afd4d5609adaa470e3d880f8be4a4d55e162b3d6
ToppCell	Bronchial-NucSeq-Immune_Lymphocytic-NK-ILC\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PRR5L OSBPL5 FCRL6 RPL19	1.16e-04	200	56	4	56d738ff019682af7f1f8cbe7b262a75dc8596d5
ToppCell	Bronchial-NucSeq-Immune_Lymphocytic-NK-ILC-T_NK-NK\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PRR5L OSBPL5 FCRL6 RPL19	1.16e-04	200	56	4	0f8e2fed93cc103b20a825d8d3e83787c5c015cc
ToppCell	distal-Hematologic-Natural_Killer\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	PRR5L OSBPL5 ARHGAP45 FCRL6	1.16e-04	200	56	4	33947befb9d32ec00f9f3e7eedaac478dcd63b20
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW26\|organoid_Tanaka_cellReport / Sample Type, Dataset, Time_group, and Cell type.	ANK2 OBSCN PLEC TMEFF2	1.16e-04	200	56	4	5c7263c862093ad9dbc81d06b16b6f74e8a6b634
ToppCell	lymphoid-T_cell-pro-T_cell\|World / Lineage, cell class and subclass	NPIPB15 OBSCN MIDEAS	1.40e-04	80	56	3	9bd3ad5029eb84efcdbf08fe268c29fa9b0b302b
ToppCell	368C-Epithelial_cells-Epithelial-B_(AT2)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	CCL28 CCDC77 ARHGAP45	3.31e-04	107	56	3	410b37beffaf637a2a64c9d0ce7baf81f4bc667c
ToppCell	368C-Epithelial_cells-Epithelial-B_(AT2)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	CCL28 CCDC77 ARHGAP45	3.31e-04	107	56	3	5bae4b3aede9bcbf7e88414e3453973cc8b0c3e7
ToppCell	droplet-Fat-Mat-18m-Mesenchymal-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDR2L PMPCA CCDC77	4.74e-04	121	56	3	e82c9e10b98c8d7ad828cf8ac19a2342014be2ba
ToppCell	Endothelial-Endothelial-A\|Endothelial / shred on cell class and cell subclass (v4)	NOP16 PAMR1 RPL19	4.86e-04	122	56	3	65849d1296934d5765afd006cbb6739383b9f49f
ToppCell	IIH-CD4-proli_CD4\|IIH / Condition, Cell_class and T cell subcluster	ANK3 OBSCN CCR7	6.95e-04	138	56	3	e474a0785a651020156baacbf89c4d2b1e4cc473
ToppCell	healthy_donor-Lymphocytic-T_cell-CD4+_T_cell_(ISG_high)\|healthy_donor / Disease condition, Lineage, Cell class and subclass	ANK3 CCR7 RNF43	6.95e-04	138	56	3	97f5dc17522462133e582b508ad0ef036e656872
ToppCell	PND07-28-samps-Mesenchymal-Myofibroblast-MyoFB-3\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	ANK2 OSBPL5 OCA2	7.40e-04	141	56	3	7ae8ead02e5aeb4106c4a30c08a7a061da3a5d6a
ToppCell	control-Myeloid-Monocyte-derived_Macrophage\|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	GON4L CCR7 CCDC77	8.18e-04	146	56	3	69e9c1ec6eec1151290227902e75e77a4aecc8db
ToppCell	15-Trachea-Immune-Immune\|Trachea / Age, Tissue, Lineage and Cell class	HTR7 NCAPD2 ARHGAP45	8.18e-04	146	56	3	ca722a89c6601e78f253d9484d01931f26161820
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_B\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	L3MBTL2 KMT2A CCR7	8.68e-04	149	56	3	14d2e8cab97108d8fa94e540c1957b73ed32dc73
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_B-B_cell\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	L3MBTL2 KMT2A CCR7	8.68e-04	149	56	3	54c9c6282f5f5de43dfaf2972fab3e3dcf9838a3
ToppCell	TCGA-Bladder-Solid_Tissue_Normal-Urothelial_normal_tissue-Urothelial_normal_tissue-4\|TCGA-Bladder / Sample_Type by Project: Shred V9	PAMR1 TRIB1 FAM135B	8.85e-04	150	56	3	bcb99c6fa81052556ab30f9db5875fccf1ae724b
ToppCell	3'_v3-Lung-Lymphocytic_T_CD4-T_CD4/CD8\|Lung / Manually curated celltypes from each tissue	ANK3 OBSCN KMT2A	9.02e-04	151	56	3	999c11d19b61d6b130ad5e623afa83cbdfe13cdd
ToppCell	Lymphoid\|World / shred on cell class and cell subclass (v4)	CCR7 ARHGAP45 RPL19	9.02e-04	151	56	3	d7577b2416b91a8be0198dea703385f86f816059
ToppCell	COVID-CD4-proli_CD4\|COVID / Condition, Cell_class and T cell subcluster	ANK3 CCR7 RPL19	9.02e-04	151	56	3	dd40dfc5b1211d31607e16d9b433a5c1796e7edf
ToppCell	356C-Lymphocytic-NK_cells-NK_cell_B2\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	PRR5L OCA2 FCRL6	9.37e-04	153	56	3	82a96ca1912858c4311b87b3b0ba5a0a41e564b5
ToppCell	BAL-Severe-Myeloid-cDC-cDC-cDC_6\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	HTR7 RECQL5 SUZ12	9.91e-04	156	56	3	0f2147abcf31a26ee5b2f4d8c5d72232612a33f0
ToppCell	BAL-Severe-Myeloid-cDC-cDC-cDC_6\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	HTR7 RECQL5 SUZ12	9.91e-04	156	56	3	cb87f12443fdc5538b856f765fcbac9406044e10
ToppCell	T_cells-GNLY+GZMB+_T_cells\|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	PRR5L OCA2 FCRL6	1.01e-03	157	56	3	e9eb56a1dd96bd2e9725a20f2cf70ddeab811bd6
ToppCell	facs-Lung-Endomucin-24m-Myeloid-Neutrophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRR5L ARHGAP45 TRIB1	1.03e-03	158	56	3	0ed844ab625351a46b74edddf082279ed1bae5c6
ToppCell	facs-Lung-Endomucin-24m-Myeloid-neutrophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRR5L ARHGAP45 TRIB1	1.03e-03	158	56	3	b3a810314e253b4fd0f578e759c36fdd21722934
ToppCell	Club_cells-Donor_02\|World / lung cells shred on cell class, cell subclass, sample id	PRR5L OSBPL5 ARHGAP28	1.05e-03	159	56	3	a7bcff268b1962a561fd2848e01ae16565bce895
ToppCell	facs-Limb_Muscle-Muscle_Diaphragm-18m-Lymphocytic-B_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ASNSD1 CCR7 ARHGAP45	1.05e-03	159	56	3	656aa20706bdba81bbcc3e68e6058215b92b8802
ToppCell	ILEUM-non-inflamed-(1)_T_cell-(1)_Cytotoxic_T_cells\|(1)_T_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	PRR5L HTR7 FCRL6	1.05e-03	159	56	3	2060e7ed5627976b48fea4a2328762b6fa308db1
ToppCell	TCGA-Liver-Primary_Tumor-Hepatocellular_Carcinoma-Hepatocellular_Carcinoma-7\|TCGA-Liver / Sample_Type by Project: Shred V9	PRR5L GLUL RNF43	1.05e-03	159	56	3	70288df54adab167c0f50675128619299077db11
ToppCell	droplet-Thymus-nan-21m-Myeloid-Macrophage\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANK2 HTR7 OBSCN	1.08e-03	161	56	3	441ebd3c029861d833fbcf8a68fc740d9de8ef2f
ToppCell	343B-Myeloid-Dendritic-cDC1\|Dendritic / Donor, Lineage, Cell class and subclass (all cells)	RNF43 FAM135B RPL19	1.08e-03	161	56	3	537a1d86de99a493b0345ca0f760994260e97049
ToppCell	saliva-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	HTR7 KMT2A CCR7	1.08e-03	161	56	3	2849fbc9611af208241b33da3cd18290aafe426b
ToppCell	ICU-SEP-Lymphocyte-T_NK-CD4_Naive\|ICU-SEP / Disease, Lineage and Cell Type	ANK3 CCR7 RPL19	1.12e-03	163	56	3	415e67aaae7ccd97a003b4b31b27eed94737deca
ToppCell	367C-Myeloid-Dendritic-cDC_proliferating_2\|367C / Donor, Lineage, Cell class and subclass (all cells)	FOXM1 NCAPD2 SUZ12	1.14e-03	164	56	3	0662cd9d21608efacc336e0a582859f3b9a4951d
Disease	Weaver syndrome	KMT2A SUZ12	3.04e-05	5	52	2	C0265210
Disease	growth rate measurement	GLUL CCDC77	1.66e-04	11	52	2	EFO_0010572
Disease	stomach carcinoma (is_implicated_in)	BCOR RNF43	1.99e-04	12	52	2	DOID:5517 (is_implicated_in)
Disease	Hypertriglyceridemia	BAZ1B TRIB1	5.11e-04	19	52	2	EFO_0004211
Disease	sensory peripheral neuropathy, remission	FOXM1 KMT2A	7.53e-04	23	52	2	EFO_0009785, MONDO_0002321
Disease	Anhedonia	ANK3 CCR7	8.20e-04	24	52	2	C0178417
Disease	aspartate aminotransferase to alanine aminotransferase ratio	BAZ1B PLEC ARHGAP45 TRIB1	8.38e-04	239	52	4	EFO_0010934
Disease	right ventricular ejection fraction measurement	OBSCN PLEC	1.28e-03	30	52	2	EFO_0021816
Disease	aseptic loosening, revision of total knee arthroplasty	ANK3 TMEFF2	2.51e-03	42	52	2	EFO_0010725, EFO_0020972
Disease	liver fat measurement	PLEC TRIB1	2.63e-03	43	52	2	EFO_0010821
Disease	schizophrenia (is_marker_for)	ANK3 GLUL	2.75e-03	44	52	2	DOID:5419 (is_marker_for)
Disease	Mood Disorders	ANK3 HTR7 GLUL	3.27e-03	168	52	3	C0525045

Protein segments in the cluster

Peptide	Gene	Start	Entry
AAVILHVKRRRICVS	CCL28	61	Q9NRJ3
RRRTIHTFPCLKELC	CDR2L	151	Q86X02
CSSPKIRRLEHRGRR	DPEP2NB	101	A0A0U1RQF7
RLRPRKTIRGKHSVI	BAZ1B	1281	Q9UIG0
RHRARVLLISKLSCV	CCR7	166	P32248
THTPVCRKRTVVSKR	CCDC77	6	Q9BR77
RLCKTKHLIPQESRR	BCOR	1361	Q6W2J9
ARRPKRTIHIDCEKR	ABHD8	151	Q96I13
SPHIRLRLSKLRRCV	OCA2	161	Q04671
PTRVTCRLVKRHRLA	ANK2	1001	Q01484
RTHRLRKLRTPAKCR	ARHGAP45	701	Q92619
PRLICVATVTRIIHR	MBTD1	506	Q05BQ5
RLICVATVKRVVHRL	L3MBTL2	551	Q969R5
RRHRGLVKRKPQACL	LRRC75A	151	Q8NAA5
RCQTKLHPLRSALRL	FCRL6	131	Q6DN72
PKRRRLSKLRTRHCT	NPIPB7	391	O75200
KRRRLSKLRTRHCTQ	NPIPB15	401	A6NHN6
TLARRHSRVRPKVTV	PRR5L	236	Q6MZQ0
RNHLVICKPRRDSRT	OBSCN	5926	Q5VST9
PLSSFVRKARHRRTL	POM121	91	Q96HA1
PLLARIKHDRRTVVC	GALNT1	221	Q10472
SRARVKTRDRTCPVH	GON4L	2081	Q3T8J9
APTRITCRLVKRHKL	ANK3	1016	Q12955
RVGRHCVVKSRSVIR	DCTN5	56	Q9BTE1
KVRPSHKRCIVILRE	LARP4	191	Q71RC2
HKPSVIVTRRRSTRI	MIDEAS	561	Q6PJG2
RRTRICHLIRPLDTV	ASNSD1	441	Q9NWL6
RSRSRRKQHLLPPCV	FOXM1	541	Q08050
TSVRGPRIKHVCRRA	KMT2A	1061	Q03164
RVTLKVSSRIPHRLS	FAM135B	31	Q49AJ0
RRIRVHTLCLPVVSS	SEC24B	991	O95487
PKRRRLSKLRTRHCT	NPIPB9	406	F8W1W9
CREPKISDLVRRRVL	PAMR1	346	Q6UXH9
PRCRKEARRLQALHE	OSBPL5	806	Q9H0X9
RRPAETNLRHTCKRI	GLUL	106	P15104
TRSRKLPHELCTLIR	PMPCA	456	Q10713
HKRRSLCSREVPLIQ	SPHKAP	1416	Q2M3C7
ITRKCPRSNRIHRQK	TMEFF2	341	Q9UIK5
RRIRVHTLCLPVVST	SEC24A	816	O95486
IRKPVTVHSRARCRK	RPL19	51	P84098
SVLRIRCRPRHSRPD	RNF43	216	Q68DV7
HKRVVAPSIIAARCR	CNEP1R1	86	Q8N9A8
ARRKAAPRIECSHIR	NOP16	26	Q9Y3C1
VLRACTRRVLLRPEK	HTR7	431	P34969
KKTTPILRASARRHR	NCAPD2	1386	Q15021
RIPRLTVKAREHCLR	RECQL5	541	O94762
RVRDLRHPKRILFCT	PRAMEF6	441	Q5VXH4
HISPKARCLIRSLLR	TRIB1	306	Q96RU8
SHPLSRKSIPRCRRI	ARHGAP28	36	Q9P2N2
KRTPITHILVCRPKR	SUZ12	521	Q15022
RVRDLRHPKRILFCT	PRAMEF5	441	Q5TYX0
CPRAKPRRRVASETH	PRRC2B	1121	Q5JSZ5
CETRTVHRLRLPLDK	PLEC	1136	Q15149
RVPVLRSCRVHLSEK	ZNF773	131	Q6PK81
KIRHRILRHTAIICT	TRAPPC8	1061	Q9Y2L5
SLARKICERVHRSPK	ZBED4	851	O75132