Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionaspartic-type endopeptidase activity

ERVK-18 ERVK-7 ERVK-21 ERVK-9 ERVK-24

5.96e-0937365GO:0004190
GeneOntologyMolecularFunctionaspartic-type peptidase activity

ERVK-18 ERVK-7 ERVK-21 ERVK-9 ERVK-24

6.86e-0938365GO:0070001
GeneOntologyMolecularFunctionstructural molecule activity

ERVK-18 ERVK-5 ERVK-7 ERVK-21 ERVK-9 NEB ERVK-24 NEBL

1.51e-04891368GO:0005198
GeneOntologyMolecularFunctionactin binding

BIN1 FBXO25 NEB NEBL MTSS2 MTSS1

1.95e-04479366GO:0003779
GeneOntologyMolecularFunctionphospholipid binding

BIN1 TNFAIP8L3 PACSIN1 ARAP2 MTSS2 MTSS1

4.02e-04548366GO:0005543
GeneOntologyMolecularFunctioncytoskeletal protein binding

AP1AR BIN1 FBXO25 NEB NEBL PACSIN1 MTSS2 MTSS1

6.24e-041099368GO:0008092
GeneOntologyMolecularFunctionactin filament binding

BIN1 NEB NEBL MTSS1

7.20e-04227364GO:0051015
GeneOntologyMolecularFunctionzinc ion binding

ERVK-5 ZFR ENPP7 ERVK-7 ERVK-21 ERVK-9 ERVK-24

9.23e-04891367GO:0008270
GeneOntologyMolecularFunctionendopeptidase activity

ERVK-18 ERVK-7 ERVK-21 ERVK-9 ERVK-24

9.84e-04430365GO:0004175
GeneOntologyMolecularFunctionactin monomer binding

MTSS2 MTSS1

1.24e-0329362GO:0003785
GeneOntologyMolecularFunctionstructural constituent of muscle

NEB NEBL

2.72e-0343362GO:0008307
GeneOntologyMolecularFunctiontransition metal ion binding

ERVK-5 ZFR ENPP7 ERVK-7 ERVK-21 ERVK-9 ERVK-24

4.75e-031189367GO:0046914
GeneOntologyBiologicalProcesscardiac muscle thin filament assembly

NEB NEBL

8.88e-063362GO:0071691
GeneOntologyBiologicalProcess1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate metabolic process

TNFAIP8L3 PIP4K2A

1.77e-054362GO:1902633
GeneOntologyBiologicalProcessplasma membrane organization

BIN1 PACSIN1 VPS4A MTSS2 MTSS1

1.79e-05188365GO:0007009
GeneOntologyBiologicalProcessviral process

ERVK-5 ERVK-7 ERVK-21 ERVK-9 ERVK-24 VPS4A

1.38e-04464366GO:0016032
GeneOntologyBiologicalProcessmembrane organization

BIN1 TNFAIP8L3 NCLN PACSIN1 VPS4A PIP4K2A MTSS2 MTSS1

1.44e-04914368GO:0061024
GeneOntologyBiologicalProcessactin filament organization

AP1AR BIN1 NEB NEBL PACSIN1 MTSS1

2.28e-04509366GO:0007015
MousePhenoabnormal sarcomere morphology

BIN1 NEB NEBL CASZ1

6.96e-0677234MP:0004090
MousePhenoabnormal Z line morphology

BIN1 NEB CASZ1

3.69e-0540233MP:0004091
MousePhenoabnormal I band morphology

BIN1 NEB CASZ1

4.28e-0542233MP:0030567
MousePhenoabnormal A band morphology

BIN1 NEB

1.16e-0410232MP:0030566
DomainMIM/ABBA

MTSS2 MTSS1

2.67e-062312IPR030127
DomainSH3_9

BIN1 NEB NEBL PACSIN1

8.13e-0678314PF14604
DomainNEBU

NEB NEBL

1.60e-054312SM00227
DomainNEBULIN

NEB NEBL

1.60e-054312PS51216
DomainNebulin

NEB NEBL

1.60e-054312PF00880
DomainNebulin_repeat

NEB NEBL

1.60e-054312IPR000900
DomainNebulin

NEB NEBL

1.60e-054312IPR013998
DomainIMD

MTSS2 MTSS1

2.66e-055312PS51338
DomainIMD

MTSS2 MTSS1

3.98e-056312PF08397
DomainSH3_1

BIN1 NEB NEBL PACSIN1

1.50e-04164314PF00018
DomainI-BAR_dom

MTSS2 MTSS1

2.06e-0413312IPR013606
DomainSH3

BIN1 NEB NEBL PACSIN1

4.28e-04216314PS50002
DomainSH3

BIN1 NEB NEBL PACSIN1

4.28e-04216314SM00326
DomainSH3_domain

BIN1 NEB NEBL PACSIN1

4.59e-04220314IPR001452
DomainWH2

MTSS2 MTSS1

7.19e-0424312PS51082
DomainRetrov_capsid_C

ERVK-5 ZSCAN18

4.30e-0359312IPR008916
Pubmed

A revised nomenclature for transcribed human endogenous retroviral loci.

ERVK-18 ERVK-5 ERVK-7 ERVK-21 ERVK-9 ERVK-24

6.05e-109436621542922
Pubmed

Expression patterns of transcribed human endogenous retrovirus HERV-K(HML-2) loci in human tissues and the need for a HERV Transcriptome Project.

ERVK-18 ERVK-21 ERVK-9 ERVK-24

2.93e-091836418664271
Pubmed

Quantitation of HERV-K env gene expression and splicing in human breast cancer.

ERVK-18 ERVK-7 ERVK-21

1.02e-08536312629516
Pubmed

Contribution of the LIM domain and nebulin-repeats to the interaction of Lasp-2 with actin filaments and focal adhesions.

NEB NEBL

1.04e-06236219851499
Pubmed

Many human endogenous retrovirus K (HERV-K) proviruses are unique to humans.

ERVK-7 ERVK-24

6.24e-06436210469592
Pubmed

Identification of Xin-repeat proteins as novel ligands of the SH3 domains of nebulin and nebulette and analysis of their interaction during myofibril formation and remodeling.

NEB NEBL

6.24e-06436223985323
Pubmed

A novel actin bundling/filopodium-forming domain conserved in insulin receptor tyrosine kinase substrate p53 and missing in metastasis protein.

MTSS2 MTSS1

6.24e-06436214752106
Pubmed

ABBA regulates plasma-membrane and actin dynamics to promote radial glia extension.

MTSS2 MTSS1

6.24e-06436218413296
Pubmed

Transcriptionally active HERV-K genes: identification, isolation, and chromosomal mapping.

ERVK-5 ERVK-7

1.04e-05536211401426
Pubmed

Multiple Src Homology 3 Binding to the Ubiquitin Ligase Itch Conserved Proline-Rich Region.

BIN1 PACSIN1

1.56e-05636226613292
Pubmed

Molecular basis of interactions between SH3 domain-containing proteins and the proline-rich region of the ubiquitin ligase Itch.

BIN1 PACSIN1

1.56e-05636228235806
Pubmed

The eleven-nineteen-leukemia protein ENL connects nuclear MLL fusion partners with chromatin.

MLLT10 AFF4

2.18e-05736215856011
Pubmed

Myopalladin, a novel 145-kilodalton sarcomeric protein with multiple roles in Z-disc and I-band protein assemblies.

NEB NEBL

2.91e-05836211309420
Pubmed

The ABBA motif binds APC/C activators and is shared by APC/C substrates and regulators.

BUB1 MTSS2

4.66e-051036225669885
Pubmed

Genomewide screening for fusogenic human endogenous retrovirus envelopes identifies syncytin 2, a gene conserved on primate evolution.

ERVK-21 ERVK-9

6.83e-051236214557543
Pubmed

Missing-in-metastasis MIM/MTSS1 promotes actin assembly at intercellular junctions and is required for integrity of kidney epithelia.

MTSS2 MTSS1

8.07e-051336221406566
Pubmed

MLL-AF9 and MLL-ENL alter the dynamic association of transcriptional regulators with genes critical for leukemia.

MLLT10 AFF4

9.41e-051436220854876
Pubmed

Nebulette knockout mice have normal cardiac function, but show Z-line widening and up-regulation of cardiac stress markers.

NEB NEBL

1.24e-041636225987543
Pubmed

Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing.

AP1AR BIN1 OXSM PACSIN1 CCDC39

1.94e-0452336511256614
Pubmed

Mapping the Ku Interactome Using Proximity-Dependent Biotin Identification in Human Cells.

ZFR JMJD1C TOP1 AFF4

2.06e-0428336430585729
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

JMJD1C TOP1 CASZ1 AFF4 ZSCAN18

3.87e-0460836536089195
Pubmed

HIV-1 Vpr induces cell cycle arrest and enhances viral gene expression by depleting CCDC137.

ZFR JMJD1C AFF4

4.86e-0414836332538781
Pubmed

GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer.

MLLT10 NEBL

5.07e-043236223535730
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

AP1AR ZFR TLK1 NEB CEP112 TOP1 PIP4K2A

6.02e-04144236735575683
Pubmed

DSSylation, a novel protein modification targets proteins induced by oxidative stress, and facilitates their degradation in cells.

TOP1 CCDC39

6.07e-043536224515614
Pubmed

Cooperative control of striated muscle mass and metabolism by MuRF1 and MuRF2.

NEB NEBL

8.33e-044136218157088
Pubmed

Characterization of the DOT1L network: implications of diverse roles for DOT1L.

MLLT10 AFF4

8.33e-044136220431927
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

RSRC2 TOP1 VPS4A AFF4 ARAP2 PIP4K2A

9.20e-04111636631753913
Pubmed

Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.

AP1AR BIN1 TRMT61B NCLN PACSIN1

9.97e-0475036511230166
Pubmed

Cancer-associated exportin-6 upregulation inhibits the transcriptionally repressive and anticancer effects of nuclear profilin-1.

TOP1 AFF4

1.00e-034536233596420
Pubmed

Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS.

NEB TOP1 AFF4 PIP4K2A

1.01e-0343236423455922
InteractionAFF1 interactions

ZFR MLLT10 AFF4 PIP4K2A

3.09e-0666314int:AFF1
Cytoband10p12

MLLT10 NEBL

1.25e-05736210p12
Cytoband2q14

BIN1 BUB1

3.27e-05113622q14
CytobandEnsembl 112 genes in cytogenetic band chr10p12

MLLT10 NEBL PIP4K2A

1.84e-04140363chr10p12
Cytoband16q22.1

VPS4A MTSS2

3.40e-0311036216q22.1
GeneFamilyI-BAR domain containing

MTSS2 MTSS1

6.42e-0651521287
CoexpressionLAKE_ADULT_KIDNEY_C22_ENDOTHELIAL_CELLS_GLOMERULAR_CAPILLARIES

CEP112 JMJD1C PIP4K2A MTSS1

1.76e-05137304M39241
CoexpressionGSE40274_FOXP3_VS_FOXP3_AND_HELIOS_TRANSDUCED_ACTIVATED_CD4_TCELL_DN

MLLT10 RSRC2 NCLN ARAP2

2.08e-05143304M9149
CoexpressionEBAUER_MYOGENIC_TARGETS_OF_PAX3_FOXO1_FUSION

BIN1 NEBL MTSS1

2.26e-0548303M16123
CoexpressionGSE41867_NAIVE_VS_DAY15_LCMV_ARMSTRONG_EFFECTOR_CD8_TCELL_DN

RSRC2 JMJD1C PIP4K2A MTSS1

7.57e-05199304M9501
CoexpressionGSE557_WT_VS_CIITA_KO_DC_DN

RSRC2 PACSIN1 AFF4 MTSS1

7.72e-05200304M6008
ToppCell3'-Airway_Nasal-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell-NK_cells|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

BIN1 NEB PACSIN1 ARAP2

4.23e-06163304e6213900f56257fe38ac7852351bea0340294be0
ToppCell3'-Airway_Nasal-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

BIN1 NEB PACSIN1 ARAP2

4.23e-06163304ed7319185c1ec384444309bb8be95691a0c2091c
ToppCell3'-Airway_Nasal-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell-NK_cells-NK_cells_L.1.3.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

BIN1 NEB PACSIN1 ARAP2

4.23e-06163304ef35d7ff09aa364734fea7fdaab6260c0a3fbf09
ToppCelldroplet-Spleen-nan-18m|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RSRC2 JMJD1C AFF4 ARAP2

6.54e-06182304eeb5dfa4539e9ca5220f26bc2b65717ddcf13b6c
ToppCelldroplet-Spleen-nan-18m-Lymphocytic|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RSRC2 JMJD1C AFF4 ARAP2

6.68e-0618330428cbf909424f3be4491d49832f0aca0386560814
ToppCelldroplet-Spleen-nan-18m-Lymphocytic-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RSRC2 JMJD1C AFF4 ARAP2

6.68e-061833043fa608aa6b119869ec3280dc388dfee57160e63a
ToppCellSepsis-ICU-SEP-Lymphocyte-T/NK-NK_CD56bright|ICU-SEP / Disease, condition lineage and cell class

BIN1 PACSIN1 ARAP2 ZSCAN18

8.94e-06197304c187e3fc2160b0165eb039cf09a6e621016068b7
ToppCellCOVID-19-COVID-19_Severe-Lymphocyte-T/NK-dn_T|COVID-19_Severe / Disease, condition lineage and cell class

BIN1 PACSIN1 ARAP2 PIP4K2A

9.49e-06200304d01aa5fccada22f97d8350ad5888df2aadb5bb1c
ToppCellmild|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

RSRC2 JMJD1C AFF4 ARAP2

9.49e-0620030412f1685ce8f218433068e090c9d839cd5a1910bf
ToppCellIonocyte-iono-4|World / Class top

ZFR TEX15 ARAP2

8.83e-0512930385ee6e16959cb58a58f5b09edf1f78d9ce6a9441
ToppCellHealthy_donor-B_cell|World / disease group, cell group and cell class (v2)

PACSIN1 CEP112 MTSS2

1.38e-04150303a2dfed562de7f58f902b547acec5a13853c80c4c
ToppCellControl-PLT_4|World / Disease Group and Platelet Clusters

JMJD1C TOP1 CASZ1

1.49e-04154303a2a03c5e6759c45aeeedf1e68ecb5a0112ef9a20
ToppCellE15.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

TNFAIP8L3 NEBL CCDC39

1.49e-04154303e65e4636646164610f33f7bbac0d879a3ea55986
ToppCellICU-SEP-Lymphocyte-T_NK-NK_CD56bright|ICU-SEP / Disease, Lineage and Cell Type

PACSIN1 ARAP2 ZSCAN18

1.61e-0415830353a942cdab4a3c6813dbe11368135a24b8de1880
ToppCellE18.5-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_G2M|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

BIN1 PIP4K2A BUB1

1.73e-04162303ec29c6f1c31e41ddcb041a49c593910edaf0532c
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_B-B_cell-B_c01-TCL1A|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TRMT61B CCDC39 MTSS2

1.93e-041683039a8709d34865cfa668d8f3335dc34fc86fc32482
ToppCellPND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CEP112 BUB1 ZSCAN18

1.96e-04169303563c267edaade0e5df192ad953801ef9768d4270
ToppCellSevere-B_naive-11|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)

BIN1 ARAP2 MTSS1

2.03e-041713037c2699f19ca38414447a286f7658f507882d57c2
ToppCell3'-Child04-06-SmallIntestine-Endothelial-lymphatic_endothelial-LEC1_(ACKR4+)|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TNFAIP8L3 CEP112 MTSS2

2.10e-0417330385083b9ce20351dd69aa2327ad087b848b4307ff
ToppCelldroplet-Heart-nan-3m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZFR CEP112 JMJD1C

2.21e-04176303749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCelldroplet-Limb_Muscle-MUSCLE-30m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RSRC2 ARAP2 MTSS1

2.29e-0417830301dafd19de04eff459253eaa9a35debf8f3deedf
ToppCellHippocampus-Neuronal-Inhibitory|Hippocampus / BrainAtlas - Mouse McCarroll V32

NEB MTSS2 MTSS1

2.44e-04182303b54ae650c04dfd0759c5f5e752b9bf684dd36516
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

NEBL CASZ1 MTSS1

2.48e-041833033c516fe5083f02bad1f464ed284010b4131a833c
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic_B-B_plasma-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

CEP112 CCDC39 BUB1

2.48e-04183303dd15e1463a0d57d14800de0df0645c81c56926ae
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

NEBL CASZ1 MTSS1

2.48e-041833039c2689d76fc6d30f5ab093428aa669d0a98953cf
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic_B-B_plasma|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

CEP112 CCDC39 BUB1

2.48e-041833038ace19c38b89556d2504258a63aa5a2b14f5cd36
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

NEBL CASZ1 MTSS1

2.52e-041843037294b379ce4cb8fa75e432559082f93cd106aaf5
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_B-B_plasma|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

ENPP7 CCDC39 BUB1

2.64e-0418730388d20f150df61ef0e3ee0c3e9895b094920c4b09
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_B-B_plasma-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

ENPP7 CCDC39 BUB1

2.64e-04187303158c2c003fd225ba61793fb06eece232fb063d05
ToppCellLA-03._Atrial_Cardiomyocyte|World / Chamber and Cluster_Paper

NEB NEBL CASZ1

2.68e-041883036d249fe92d51a19da19ec14bb2262d394255d577
ToppCell3'_v3-blood-Lymphocytic_T_CD8-Trm/em_CD8|blood / Manually curated celltypes from each tissue

PACSIN1 ARAP2 PIP4K2A

2.68e-0418830321730497f95dc271e4cdfaaf1da8b9ac6eec2ded
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

BIN1 TLK1 ARAP2

2.77e-0419030391ba66d4b56c59523485b17738e93f14bb00afa4
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c09-GZMK-FOS_l|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

BIN1 ARAP2 PIP4K2A

2.81e-04191303b9ef6d82b86271b7e0875a399bb9aae84ef5bad3
ToppCellfacs-Aorta-Heart-3m|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARAP2 PIP4K2A MTSS1

2.85e-041923031ccc47792edf9ee23501c8e2165d11271636b66a
ToppCellfacs-Thymus-nan-3m-Lymphocytic-DN_to_DP_transition_(most_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NEBL PIP4K2A MTSS1

2.90e-04193303a6a864644e1b80b7417ea0a27281e79068a3fd3d
ToppCellNS-moderate-d_0-4|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CCDC39 MTSS1 ZSCAN18

2.90e-04193303ea345d34440b25f65358a53dc72831998d1c3620
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c03-GZMK|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

BIN1 ARAP2 PIP4K2A

2.90e-04193303523e2541f9f8d22b3c5263839a57cc1ab23d4963
ToppCellCOVID-19_Mild-PLT_4|World / Disease Group and Platelet Clusters

RSRC2 JMJD1C TOP1

2.90e-0419330398a52523aa1efd5d14a2878ed106828a80a33aa2
ToppCellnormal_Lymph_Node-T/NK_cells-CD8_low_T|T/NK_cells / Location, Cell class and cell subclass

PACSIN1 ARAP2 PIP4K2A

2.90e-0419330348809047d3194aff225fc43c3d5152c20434fe62
ToppCellnormal_Lymph_Node-T/NK_cells-CD8_low_T|normal_Lymph_Node / Location, Cell class and cell subclass

PACSIN1 ARAP2 PIP4K2A

2.90e-04193303e20ad6b62ad3aa386aa10b7a5d057d24a64ad386
ToppCellCOVID-19_Convalescent-PLT_4|COVID-19_Convalescent / Disease Group and Platelet Clusters

RSRC2 JMJD1C TOP1

2.94e-04194303ce1fad4e76a87f0c35e430ed1f2262395df882fd
ToppCellnormal-na-Lymphocytic_NK-NK_bright|normal / PBMC cell types (v2) per disease, treatment status, and sex

PACSIN1 ARAP2 PIP4K2A

2.94e-041943038c5f716ce05c1f187de63c1b6948eb9f90ff34fe
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c03-GZMK|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

PACSIN1 CASZ1 PIP4K2A

2.94e-04194303b0a7f5ca0c6f4f5764a8b35b5de80d82b828c66c
ToppCellnormal-na-Lymphocytic_NK-NK_bright-female|normal / PBMC cell types (v2) per disease, treatment status, and sex

PACSIN1 ARAP2 PIP4K2A

2.94e-04194303dc4aeee379423827e8d291cffe4dbdf2ff6d0bbe
ToppCellfacs-Thymus-nan-3m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NEBL PIP4K2A MTSS1

2.99e-0419530379114b3c78cc15c413bb58f0673e7215b784a9b6
ToppCell3'_v3-blood-Lymphocytic_NK-NK_CD56bright_CD16-|blood / Manually curated celltypes from each tissue

PACSIN1 CASZ1 ARAP2

2.99e-041953031470f562ebcfe7da367964ecfd6c7f43bcdb4a73
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Mesenchymal|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NEB CEP112 JMJD1C

2.99e-041953035c86fddd6d0530beecf45ea5ba6b823123847696
ToppCell10x3'2.3-week_17-19-Mesenchymal_myocytic-stroma-muscle|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

BIN1 NEB MTSS2

2.99e-0419530380b973d2a23ef9b101c90e1635e68c9a3f78f65d
ToppCellCV-Moderate-6|CV / Virus stimulation, Condition and Cluster

AP1AR AFF4 MTSS1

3.03e-041963037bced0cc2112697593c478fa291b8ed3941fb811
ToppCellILEUM-non-inflamed-(6)_ILC-(6)_ILC1|(6)_ILC / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

BIN1 ARAP2 PIP4K2A

3.03e-041963038a3a63129adfbe58558af91336f81d397c291ed0
ToppCellILEUM-inflamed-(6)_ILC-(6)_ILC1|(6)_ILC / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

BIN1 ARAP2 PIP4K2A

3.03e-04196303c1d84d2e4ecc83134c3c694bed3cf035bd2742af
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c03-GZMK|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PACSIN1 ARAP2 PIP4K2A

3.03e-0419630317f17edadafdad9f24e88d708d7e1c765503131c
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_II-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

BIN1 TNFAIP8L3 MTSS1

3.08e-04197303b597c292fc1cb381a4325fed15a32966c38def28
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

BIN1 ARAP2 PIP4K2A

3.08e-0419730335004d4728d33f15cc3be99a073b1ea965365c32
ToppCellControl-PLT_4|Control / Disease Group and Platelet Clusters

RSRC2 JMJD1C TOP1

3.12e-04198303387fd3037fd52e4d4c42de0588767e58af228b59
ToppCellTCGA-Skin-Metastatic-Melanoma|TCGA-Skin / Sample_Type by Project: Shred V9

ZFR JMJD1C TOP1

3.12e-04198303af4fb9eb2295c7b90624b38ba25619aa15254efa
ToppCellSevere-B_memory-3|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)

BIN1 PIP4K2A MTSS1

3.12e-04198303a3050c126799e32f742a14396236572250476820
ToppCellTCGA-Skin-Metastatic-Melanoma-Skin_Cutaneous_Melanoma|TCGA-Skin / Sample_Type by Project: Shred V9

ZFR JMJD1C TOP1

3.12e-0419830362cbf4b29e8af4983fb47a17f96da62682a5137e
ToppCell10x_3'_v3-blood_(10x_3'_v3)-lymphocytic-T_lymphocytic-CD8-positive,_alpha-beta_cytokine_secreting_effector_T_cell|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

BIN1 ARAP2 PIP4K2A

3.12e-0419830334c564ece9a2b94dcf646e3c95b5be9c5ecfaafe
ToppCellTCGA-Skin-Metastatic|TCGA-Skin / Sample_Type by Project: Shred V9

ZFR JMJD1C TOP1

3.12e-04198303ad39cce004867f083f8da1954e0cf5a263815184
ToppCellCOVID-19_Mild-PLT_4|COVID-19_Mild / Disease Group and Platelet Clusters

RSRC2 JMJD1C TOP1

3.12e-041983033d8c33dba759df0974aeb2b9a6b5167ae7a18e1f
ToppCellhuman_hepatoblastoma-Tumor_cells-T9|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

RSRC2 TOP1 AFF4

3.17e-04199303e9c83555d2197b740797a9f33b64f8f7a7ba1ee2
ToppCellCOVID_vent-Lymphocytic-ILC|COVID_vent / Disease condition, Lineage, Cell class and subclass

ARAP2 PIP4K2A MTSS1

3.17e-04199303e3ff7fa1b1de1aaf6b46cdf49afa95bad457728a
ToppCellCOVID_vent-Lymphocytic-ILC-NK_cell|COVID_vent / Disease condition, Lineage, Cell class and subclass

ARAP2 PIP4K2A MTSS1

3.17e-041993035f914962e2572b0c6372465b81b7496fa663d93c
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_aging_sig-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

BIN1 TNFAIP8L3 MTSS1

3.17e-04199303b0a906586e58009f5ed9272fc29ba28e49c85ee6
ToppCellCOVID-19-COVID-19_Mild-Lymphocyte-T/NK-dn_T|COVID-19_Mild / Disease, condition lineage and cell class

PACSIN1 ARAP2 PIP4K2A

3.17e-04199303f307d4887b28cf60a591439e278fd668409cb104
ToppCellControl-Control-Lymphocyte-T/NK-dn_T|Control / Disease, condition lineage and cell class

BIN1 PACSIN1 PIP4K2A

3.22e-0420030310882c59b7aaf8bd4b5c00aa4ddbb9f7ac5b2cf5
ToppCellBrain_organoid-organoid_Tanaka_cellReport-6m-Neuronal-Intermediate|6m / Sample Type, Dataset, Time_group, and Cell type.

RSRC2 NEB JMJD1C

3.22e-042003037c261e39ac30b318511373ab7302aa53b8b81b9c
ToppCellCOVID-19|World / Disease, condition lineage and cell class

RSRC2 TOP1 AFF4

3.22e-042003037dec470c379cd89f05a0f37c8628b21f136e52f0
ToppCellCOVID-19-COVID-19_Severe-Lymphocyte-T/NK-NK_CD56bright|COVID-19_Severe / Disease, condition lineage and cell class

PACSIN1 ARAP2 ZSCAN18

3.22e-0420030312626d046a3ed8db1c9bd603ada5b97ead93e587
DrugNicardipine hydrochloride [54527-84-3]; Down 200; 7.8uM; MCF7; HT_HG-U133A

BIN1 MLLT10 CASZ1 AFF4 MTSS2

5.51e-061973053215_DN
DrugIsocorydine (+) [475-67-2]; Down 200; 11.8uM; PC3; HT_HG-U133A

BIN1 MLLT10 NEB NEBL AFF4

5.93e-062003054505_DN
DrugQuercetine dihydrate [6151-25-3]; Down 200; 11.8uM; MCF7; HT_HG-U133A

TRMT61B NEB NEBL ARAP2

8.82e-051803042859_DN
DrugLevonordefrin [829-74-3]; Up 200; 21.8uM; PC3; HT_HG-U133A

MLLT10 NEB NEBL AFF4

1.02e-041873045854_UP
DrugChlorambucil [305-03-3]; Down 200; 13.2uM; PC3; HT_HG-U133A

ZFR TLK1 AFF4 BUB1

1.06e-041893043788_DN
DrugTrichostatin A, from Streptomyces sp.; Up 200; 0.1uM; HL60; HT_HG-U133A

BIN1 TEX15 NEBL MTSS1

1.13e-041923042523_UP
DrugIndomethacin [53-86-1]; Up 200; 11.2uM; HL60; HT_HG-U133A

BIN1 NEBL PACSIN1 MTSS1

1.18e-041943042377_UP
DrugPyrilamine maleate [59-33-6]; Up 200; 10uM; PC3; HT_HG-U133A

TEX15 MLLT10 NEB AFF4

1.18e-041943045869_UP
DrugDomperidone maleate; Down 200; 7.4uM; MCF7; HT_HG-U133A

AP1AR ZFR MLLT10 BUB1

1.18e-041943042655_DN
DrugChicago sky blue 6B [2610-05-1]; Up 200; 4uM; PC3; HT_HG-U133A

ZFR TLK1 TEX15 AFF4

1.20e-041953046626_UP
DrugTestosterone propionate [57-85-2]; Down 200; 11.6uM; MCF7; HT_HG-U133A

ZFR BIN1 NEBL AFF4

1.20e-041953042649_DN
Drugoxaprozin; Down 200; 300uM; MCF7; HT_HG-U133A_EA

ZFR BIN1 MLLT10 MTSS2

1.20e-04195304863_DN
DrugEstropipate [7280-37-7]; Down 200; 9.2uM; PC3; HT_HG-U133A

TEX15 MLLT10 NEB CASZ1

1.22e-041963044472_DN
DrugSulfaguanidine [57-67-0]; Down 200; 18.6uM; PC3; HT_HG-U133A

AP1AR BIN1 MLLT10 CEP112

1.22e-041963044257_DN
DrugThioproperazine dimesylate [2347-80-0]; Up 200; 6.2uM; MCF7; HT_HG-U133A

BIN1 NEB PACSIN1 ZSCAN18

1.22e-041963042236_UP
DrugSulfanilamide [63-74-1]; Down 200; 23.2uM; PC3; HT_HG-U133A

BIN1 TEX15 MLLT10 NEB

1.25e-041973044474_DN
DrugFlavoxate hydrochloride [3717-88-2]; Up 200; 9.4uM; MCF7; HT_HG-U133A

BIN1 TLK1 TEX15 NEBL

1.25e-041973047405_UP
DrugFenbendazole [43210-67-9]; Up 200; 13.4uM; HL60; HT_HG-U133A

MLLT10 NEBL PIP4K2A MTSS2

1.25e-041973042360_UP
DrugSB 203580; Down 200; 1uM; MCF7; HT_HG-U133A

BIN1 TLK1 NEB NEBL

1.25e-041973047061_DN
DrugFlavoxate hydrochloride [3717-88-2]; Down 200; 9.4uM; PC3; HT_HG-U133A

ZFR BIN1 MLLT10 PIP4K2A

1.25e-041973046326_DN
DrugClorsulon [60200-06-8]; Up 200; 10.6uM; PC3; HT_HG-U133A

AP1AR MLLT10 CEP112 BUB1

1.25e-041973047264_UP
DrugHarmalol hydrochloride dihydrate [6028-07-5]; Up 200; 14.6uM; PC3; HT_HG-U133A

NEBL AFF4 BUB1 MTSS2

1.25e-041973045076_UP
DrugCefepime hydrochloride [123171-59-5]; Up 200; 7.4uM; PC3; HT_HG-U133A

TEX15 MLLT10 BUB1 MTSS2

1.25e-041973045761_UP
DrugTiaprofenic acid [33005-95-7]; Down 200; 15.4uM; PC3; HT_HG-U133A

BIN1 MLLT10 NEB NEBL

1.25e-041973044091_DN
DrugPhentolamine hydrochloride [73-05-2]; Up 200; 12.6uM; HL60; HT_HG-U133A

MLLT10 NEB NEBL PIP4K2A

1.25e-041973042362_UP
DrugOxyphenbutazone [129-20-4]; Down 200; 12.4uM; PC3; HT_HG-U133A

MLLT10 NEB NEBL BUB1

1.25e-041973044506_DN
DrugGentamicine sulfate [1405-41-0]; Up 200; 2.6uM; PC3; HT_HG-U133A

MLLT10 NEB NEBL AFF4

1.25e-041973045883_UP
DrugCarbimazole [22232-54-8]; Up 200; 21.4uM; HL60; HT_HG-U133A

NEB NEBL MTSS2 MTSS1

1.27e-041983042437_UP
DrugPhensuximide [86-34-0]; Down 200; 21.2uM; HL60; HT_HG-U133A

ZFR BIN1 NEB PIP4K2A

1.27e-041983042960_DN
Drughaloperidol; Down 200; 10uM; PC3; HT_HG-U133A

ZFR NEBL AFF4 BUB1

1.27e-041983044468_DN
DrugOxaprozin [21256-18-8]; Up 200; 13.6uM; MCF7; HT_HG-U133A

BIN1 CEP112 BUB1 MTSS1

1.27e-041983044352_UP
DrugTocopherol (R,S) [10191-41-0]; Up 200; 9.2uM; PC3; HT_HG-U133A

TLK1 TEX15 NEBL BUB1

1.27e-041983046616_UP
DrugEtidronic acid, disodium salt [7414-83-7]; Up 200; 16uM; MCF7; HT_HG-U133A

BIN1 TEX15 CEP112 BUB1

1.27e-041983043325_UP
DrugAG-012559 [369370-06-9]; Down 200; 10uM; MCF7; HT_HG-U133A

BIN1 NCLN NEB NEBL

1.27e-041983046889_DN
DrugAspartic acid, N-acetyl (R,S) [997-55-7]; Down 200; 22.8uM; PC3; HT_HG-U133A

BIN1 MLLT10 BUB1 MTSS2

1.30e-041993044007_DN
DrugDinoprost trometamol [38362-01-5]; Down 200; 8.4uM; PC3; HT_HG-U133A

BIN1 MLLT10 NEB NEBL

1.30e-041993046308_DN
DrugRifampicin [13292-46-1]; Up 200; 4.8uM; PC3; HT_HG-U133A

TLK1 TEX15 MLLT10 MTSS1

1.30e-041993044008_UP
DrugSR-95639A [115767-94-7]; Down 200; 10uM; PC3; HT_HG-U133A

BIN1 AFF4 PIP4K2A MTSS1

1.30e-041993046632_DN
DrugHomosalate [118-56-9]; Up 200; 15.2uM; PC3; HT_HG-U133A

TLK1 NEBL AFF4 BUB1

1.30e-041993044533_UP
Drug5149715; Up 200; 10uM; MCF7; HT_HG-U133A_EA

TLK1 NEB NEBL CASZ1

1.30e-04199304890_UP
DrugLevodopa [59-92-7]; Up 200; 20.2uM; PC3; HT_HG-U133A

NEB AFF4 MTSS2 ZSCAN18

1.30e-041993044571_UP
DrugNomifensine maleate [32795-47-4]; Up 200; 11.2uM; MCF7; HT_HG-U133A

BIN1 TLK1 MLLT10 PACSIN1

1.32e-042003042224_UP
Diseaseintellectual developmental disorder with ocular anomalies and distinctive facial features (implicated_via_orthology)

MTSS2 MTSS1

9.99e-072302DOID:0081301 (implicated_via_orthology)
DiseaseDickkopf-related protein 4 measurement

CEP112 JMJD1C

2.79e-058302EFO_0008110
Diseasecreatine kinase measurement

BIN1 NEB CEP112

2.97e-0559303EFO_0004534
Diseaseattention deficit hyperactivity disorder (implicated_via_orthology)

FBXO25 VPS4A

3.72e-0428302DOID:1094 (implicated_via_orthology)
Diseasegait measurement

MLLT10 NEBL JMJD1C

4.73e-04150303EFO_0007680
Diseasecryptic phenotype measurement

MLLT10 CASZ1

1.05e-0347302EFO_0021487
Diseasemetabolic syndrome

MLLT10 JMJD1C ARAP2

1.09e-03200303EFO_0000195
Diseasehealth literacy measurement

TLK1 FBXO25

1.33e-0353302EFO_0010104
Diseaseasthma, endometriosis

MLLT10 CEP112

2.58e-0374302EFO_0001065, MONDO_0004979
Diseaseinterleukin 10 measurement

NEBL JMJD1C

2.86e-0378302EFO_0004750
Diseasebreast carcinoma

MLLT10 NEBL JMJD1C CASZ1 PIP4K2A

3.38e-031019305EFO_0000305
Diseaseinfluenza A (H1N1)

ARAP2 PIP4K2A

3.54e-0387302EFO_1001488
Diseasephysical activity

ARAP2 PIP4K2A

3.62e-0388302EFO_0003940
Diseaselipid measurement, intermediate density lipoprotein measurement

JMJD1C TOP1

4.29e-0396302EFO_0004529, EFO_0008595
Diseasephospholipid measurement, intermediate density lipoprotein measurement

JMJD1C TOP1

4.56e-0399302EFO_0004639, EFO_0008595
DiseaseAdenoid Cystic Carcinoma

TLK1 JMJD1C

4.65e-03100302C0010606
Diseasesodium measurement

MLLT10 JMJD1C

4.93e-03103302EFO_0009282
Diseaseimmature platelet count

TLK1 JMJD1C

5.21e-03106302EFO_0803544
Diseasegallstones

MLLT10 JMJD1C

5.40e-03108302EFO_0004210
Diseaseatrial fibrillation

NEBL JMJD1C CASZ1

6.22e-03371303EFO_0000275
Diseaseglycoprotein measurement

CEP112 MTSS2

6.52e-03119302EFO_0004555
Diseaseimmature platelet measurement

TLK1 JMJD1C

6.52e-03119302EFO_0803541
Diseaseplatelet component distribution width

TLK1 PACSIN1 JMJD1C MTSS1

6.87e-03755304EFO_0007984
DiseaseC-reactive protein measurement

BIN1 TLK1 MLLT10 TOP1 AFF4

6.88e-031206305EFO_0004458

Protein segments in the cluster

PeptideGeneStartEntry
ESLDKHKHKKLQSFY

ERVK-18

186

O42043
ESLDKHKHKKLQSFY

ERVK-9

296

Q9UKH3
HLMKEFLDKKKYHND

BUB1

51

O43683
FKNKCDIEKHKSYHI

CASZ1

621

Q86V15
DAAKLKYKKANEEHH

C4orf47

171

A7E2U8
EKSHLKHIYEKKAHD

CEP112

541

Q8N8E3
HKTKKNDDPSKDYHV

ARAP2

81

Q8WZ64
HYDSIAEKQKDLDKK

AP1AR

76

Q63HQ0
DHYLQEAKKLKHNAD

AFF4

916

Q9UHB7
KKLHNDLYFIKKAHS

CCDC39

506

Q9UFE4
YLKDVKQHHVKADKR

NCLN

486

Q969V3
KAIKHLFKDHAYALA

OXSM

361

Q9NWU1
HLKKHKAALAAAQYK

JMJD1C

1481

Q15652
KAANQLDKDHAKEYK

MTSS2

116

Q765P7
KKVANQLDKDHAKEY

MTSS1

116

O43312
QLDKDHAKEYKKARQ

MTSS1

121

O43312
NNEEHEYASKKRKKD

FBXO25

56

Q8TCJ0
KELEAAKKAYHLACK

PACSIN1

151

Q9BY11
AKKAYHLACKEEKLA

PACSIN1

156

Q9BY11
ESLDKHKHKKLQSFY

ERVK-24

186

P61566
ESLDKHKHKKLQSFY

ERVK-7

186

P61567
YKLKKEHNEFHANKA

GJA9

246

P57773
ESLDKHKHKKLQSFY

ERVK-21

296

P61565
ESLDKHKHKKLQSFY

ERVK-5

186

Q9HDB8
KDAHPKLHVYKKEAF

ENPP7

301

Q6UWV6
HYESLQTAKKKDEAK

BIN1

156

O00499
LTHYDAKKKAAHAAK

PIP4K2A

361

P48426
KKHKSEEHNDKEHSS

RSRC2

81

Q7L4I2
SHSQDKHHEKEKKKY

MLLT10

221

P55197
KSWRDEKKENYHKHA

TLK1

491

Q9UKI8
DELYKVTKEHTHNKK

TNFAIP8L3

146

Q5GJ75
KDHHDLAKKNYKHWR

TRMT61B

281

Q9BVS5
YKEHLEGQKHKKKEA

ZFR

346

Q96KR1
LAEHQKTHEKEKSYA

ZSCAN18

456

Q8TBC5
KYEKLEKHSANHNVK

TEX15

1201

Q9BXT5
FRLNDSHKHKDKHKD

TOP1

16

P11387
HAIKYEAHSDKAKES

VPS4A

41

Q9UN37
YKEKFDNEMKDKKHH

NEBL

231

O76041
LNYKAKHEGEKFKCH

NEB

771

P20929
LVSENKYKDHVKKHL

NEB

5646

P20929