| Category | Name | IntersectionWithQuery | PValue | GenesInTerm | GenesInQuery | GenesInTermInQuery | ID |
|---|---|---|---|---|---|---|---|
| Domain | WD40 | 4.46e-06 | 268 | 47 | 7 | SM00320 | |
| Domain | WD40_repeat | 4.92e-06 | 272 | 47 | 7 | IPR001680 | |
| Domain | WD_REPEATS_1 | 5.67e-06 | 278 | 47 | 7 | PS00678 | |
| Domain | WD_REPEATS_2 | 5.81e-06 | 279 | 47 | 7 | PS50082 | |
| Domain | WD_REPEATS_REGION | 5.81e-06 | 279 | 47 | 7 | PS50294 | |
| Domain | WD40_repeat_dom | 8.74e-06 | 297 | 47 | 7 | IPR017986 | |
| Domain | - | 1.83e-05 | 333 | 47 | 7 | 2.130.10.10 | |
| Domain | WD40/YVTN_repeat-like_dom | 1.90e-05 | 335 | 47 | 7 | IPR015943 | |
| Domain | RCC1/BLIP-II | 2.55e-05 | 23 | 47 | 3 | IPR009091 | |
| Domain | WD40 | 4.47e-05 | 259 | 47 | 6 | PF00400 | |
| Domain | PAN_AP | 6.17e-05 | 5 | 47 | 2 | SM00473 | |
| Domain | PAN | 1.29e-04 | 7 | 47 | 2 | PS50948 | |
| Domain | Pan_app | 1.29e-04 | 7 | 47 | 2 | IPR003609 | |
| Domain | PAN_1 | 1.29e-04 | 7 | 47 | 2 | PF00024 | |
| Domain | Kringle | 8.23e-04 | 17 | 47 | 2 | IPR000001 | |
| Domain | Kringle_CS | 8.23e-04 | 17 | 47 | 2 | IPR018056 | |
| Domain | KRINGLE_2 | 8.23e-04 | 17 | 47 | 2 | PS50070 | |
| Domain | Kringle | 8.23e-04 | 17 | 47 | 2 | PF00051 | |
| Domain | KRINGLE_1 | 8.23e-04 | 17 | 47 | 2 | PS00021 | |
| Domain | KR | 8.23e-04 | 17 | 47 | 2 | SM00130 | |
| Domain | RCC1 | 1.14e-03 | 20 | 47 | 2 | PF00415 | |
| Domain | RCC1_1 | 1.26e-03 | 21 | 47 | 2 | PS00625 | |
| Domain | RCC1_2 | 1.26e-03 | 21 | 47 | 2 | PS00626 | |
| Domain | RCC1_3 | 1.26e-03 | 21 | 47 | 2 | PS50012 | |
| Domain | Reg_chr_condens | 1.39e-03 | 22 | 47 | 2 | IPR000408 | |
| Domain | - | 1.39e-03 | 22 | 47 | 2 | 2.130.10.30 | |
| Domain | Kringle-like | 2.93e-03 | 32 | 47 | 2 | IPR013806 | |
| Domain | Chromo/shadow_dom | 3.11e-03 | 33 | 47 | 2 | IPR000953 | |
| Domain | CHROMO | 3.11e-03 | 33 | 47 | 2 | SM00298 | |
| Domain | Kazal_2 | 3.70e-03 | 36 | 47 | 2 | PF07648 | |
| Domain | KAZAL | 5.98e-03 | 46 | 47 | 2 | SM00280 | |
| Domain | KAZAL_2 | 7.03e-03 | 50 | 47 | 2 | PS51465 | |
| Domain | Kazal_dom | 7.31e-03 | 51 | 47 | 2 | IPR002350 | |
| Pathway | REACTOME_SIGNALING_BY_MST1 | 8.93e-05 | 6 | 35 | 2 | MM15492 | |
| Pathway | BIOCARTA_MSP_PATHWAY | 1.25e-04 | 7 | 35 | 2 | MM1580 | |
| Pathway | WP_MIR302367_PROMOTING_CARDIOMYOCYTE_PROLIFERATION | 1.66e-04 | 8 | 35 | 2 | MM15986 | |
| Pubmed | 1.79e-06 | 2 | 47 | 2 | 10728827 | ||
| Pubmed | 1.79e-06 | 2 | 47 | 2 | 16961763 | ||
| Pubmed | Inhibiting endothelial cell Mst1 attenuates acute lung injury in mice. | 1.79e-06 | 2 | 47 | 2 | 39253972 | |
| Pubmed | Mst1 regulates post-infarction cardiac injury through the JNK-Drp1-mitochondrial fission pathway. | 1.79e-06 | 2 | 47 | 2 | 29760744 | |
| Pubmed | 1.79e-06 | 2 | 47 | 2 | 32017081 | ||
| Pubmed | Mst1 inhibition attenuates non-alcoholic fatty liver disease via reversing Parkin-related mitophagy. | 1.79e-06 | 2 | 47 | 2 | 30708325 | |
| Pubmed | 1.79e-06 | 2 | 47 | 2 | 24409221 | ||
| Pubmed | Melatonin alleviates postinfarction cardiac remodeling and dysfunction by inhibiting Mst1. | 1.79e-06 | 2 | 47 | 2 | 27696525 | |
| Pubmed | 1.79e-06 | 2 | 47 | 2 | 8393443 | ||
| Pubmed | Hepatocyte-specific expression of the mouse hepatocyte growth factor-like protein. | 1.79e-06 | 2 | 47 | 2 | 8340069 | |
| Pubmed | Biological effects of targeted inactivation of hepatocyte growth factor-like protein in mice. | 1.79e-06 | 2 | 47 | 2 | 9486989 | |
| Pubmed | 1.79e-06 | 2 | 47 | 2 | 27609031 | ||
| Pubmed | 1.79e-06 | 2 | 47 | 2 | 24980820 | ||
| Pubmed | Treatment with XMU-MP-1 erases hyperglycaemic memory in hearts of diabetic mice. | 1.79e-06 | 2 | 47 | 2 | 33887258 | |
| Pubmed | 1.79e-06 | 2 | 47 | 2 | 38086857 | ||
| Pubmed | 1.79e-06 | 2 | 47 | 2 | 25938541 | ||
| Pubmed | 1.79e-06 | 2 | 47 | 2 | 31206688 | ||
| Pubmed | 5.36e-06 | 3 | 47 | 2 | 27496379 | ||
| Pubmed | 5.36e-06 | 3 | 47 | 2 | 12804176 | ||
| Pubmed | 5.36e-06 | 3 | 47 | 2 | 12606483 | ||
| Pubmed | The Ron/STK receptor tyrosine kinase is essential for peri-implantation development in the mouse. | 5.36e-06 | 3 | 47 | 2 | 10225971 | |
| Pubmed | Mst1-mediated phosphorylation of Nur77 improves the endometrial receptivity in human and mice. | 5.36e-06 | 3 | 47 | 2 | 36623453 | |
| Pubmed | 5.36e-06 | 3 | 47 | 2 | 37184367 | ||
| Pubmed | 5.36e-06 | 3 | 47 | 2 | 38430683 | ||
| Pubmed | 5.36e-06 | 3 | 47 | 2 | 12538524 | ||
| Pubmed | Mst1 controls lymphocyte trafficking and interstitial motility within lymph nodes. | 5.36e-06 | 3 | 47 | 2 | 19339990 | |
| Pubmed | TRAF2 functions as an activator switch in the reactive oxygen species-induced stimulation of MST1. | 5.36e-06 | 3 | 47 | 2 | 26698664 | |
| Pubmed | 5.36e-06 | 3 | 47 | 2 | 38288506 | ||
| Pubmed | The proto-oncogene RON is involved in development of epithelial, bone and neuro-endocrine tissues. | 5.36e-06 | 3 | 47 | 2 | 8545120 | |
| Pubmed | 5.36e-06 | 3 | 47 | 2 | 25049204 | ||
| Pubmed | 5.36e-06 | 3 | 47 | 2 | 1832957 | ||
| Pubmed | 5.36e-06 | 3 | 47 | 2 | 25183307 | ||
| Pubmed | 5.36e-06 | 3 | 47 | 2 | 35525373 | ||
| Pubmed | MST1 coordinately regulates autophagy and apoptosis in diabetic cardiomyopathy in mice. | 5.36e-06 | 3 | 47 | 2 | 27510910 | |
| Pubmed | 5.36e-06 | 3 | 47 | 2 | 30063115 | ||
| Pubmed | 5.36e-06 | 3 | 47 | 2 | 31976559 | ||
| Pubmed | Mst1-mediated phosphorylation of Bcl-xL is required for myocardial reperfusion injury. | 5.36e-06 | 3 | 47 | 2 | 27218122 | |
| Pubmed | Over-expressed MST1 impaired spatial memory via disturbing neural oscillation patterns in mice. | 5.36e-06 | 3 | 47 | 2 | 32468668 | |
| Pubmed | 5.36e-06 | 3 | 47 | 2 | 17395874 | ||
| Pubmed | Nicorandil alleviates myocardial injury and post-infarction cardiac remodeling by inhibiting Mst1. | 5.36e-06 | 3 | 47 | 2 | 29127009 | |
| Pubmed | Mst1 Kinase Regulates the Actin-Bundling Protein L-Plastin To Promote T Cell Migration. | 5.36e-06 | 3 | 47 | 2 | 27465533 | |
| Pubmed | Genetic deletion of Mst1 alters T cell function and protects against autoimmunity. | 5.36e-06 | 3 | 47 | 2 | 24852423 | |
| Pubmed | 5.36e-06 | 3 | 47 | 2 | 30771091 | ||
| Pubmed | MST1 mediates the N-methyl-D-aspartate-induced excitotoxicity in mouse cortical neurons. | 5.36e-06 | 3 | 47 | 2 | 34967918 | |
| Pubmed | 5.36e-06 | 3 | 47 | 2 | 38898027 | ||
| Pubmed | WASP and Mst1 coregulate B-cell development and B-cell receptor signaling. | 5.36e-06 | 3 | 47 | 2 | 32045478 | |
| Pubmed | 5.36e-06 | 3 | 47 | 2 | 27940445 | ||
| Pubmed | Mst1 regulates hepatic lipid metabolism by inhibiting Sirt1 ubiquitination in mice. | 1.07e-05 | 4 | 47 | 2 | 26903296 | |
| Pubmed | 1.07e-05 | 4 | 47 | 2 | 23527007 | ||
| Pubmed | A cell-intrinsic role for Mst1 in regulating thymocyte egress. | 1.07e-05 | 4 | 47 | 2 | 19692642 | |
| Pubmed | 1.07e-05 | 4 | 47 | 2 | 21078906 | ||
| Pubmed | MST1 controls murine neutrophil homeostasis via the G-CSFR/STAT3 axis. | 1.07e-05 | 4 | 47 | 2 | 36618429 | |
| Pubmed | Melatonin protects against diabetic cardiomyopathy through Mst1/Sirt3 signaling. | 1.07e-05 | 4 | 47 | 2 | 28480597 | |
| Pubmed | 1.07e-05 | 4 | 47 | 2 | 16892067 | ||
| Pubmed | 1.07e-05 | 4 | 47 | 2 | 23826075 | ||
| Pubmed | 1.07e-05 | 4 | 47 | 2 | 25659841 | ||
| Pubmed | 1.07e-05 | 4 | 47 | 2 | 35715527 | ||
| Pubmed | 1.07e-05 | 4 | 47 | 2 | 26538561 | ||
| Pubmed | MST1 functions as a key modulator of neurodegeneration in a mouse model of ALS. | 1.07e-05 | 4 | 47 | 2 | 23818595 | |
| Pubmed | 1.07e-05 | 4 | 47 | 2 | 25074980 | ||
| Pubmed | 1.07e-05 | 4 | 47 | 2 | 35626096 | ||
| Pubmed | 1.07e-05 | 4 | 47 | 2 | 22926556 | ||
| Pubmed | 1.07e-05 | 4 | 47 | 2 | 27825852 | ||
| Pubmed | 1.07e-05 | 4 | 47 | 2 | 32987643 | ||
| Pubmed | The Mst1 Kinase Is Required for Follicular B Cell Homing and B-1 B Cell Development. | 1.07e-05 | 4 | 47 | 2 | 30386341 | |
| Pubmed | 1.07e-05 | 4 | 47 | 2 | 28527887 | ||
| Pubmed | Mst1 directs Myosin IIa partitioning of low and higher affinity integrins during T cell migration. | 1.07e-05 | 4 | 47 | 2 | 25133611 | |
| Pubmed | 1.07e-05 | 4 | 47 | 2 | 32627655 | ||
| Pubmed | Macrophage MST1/2 Disruption Impairs Post-Infarction Cardiac Repair via LTB4. | 1.07e-05 | 4 | 47 | 2 | 34515499 | |
| Pubmed | 1.07e-05 | 4 | 47 | 2 | 27919044 | ||
| Pubmed | Mst1/2 Kinases Modulate Glucose Uptake for Osteoblast Differentiation and Bone Formation. | 1.07e-05 | 4 | 47 | 2 | 29474739 | |
| Pubmed | mTORC2 regulates cardiac response to stress by inhibiting MST1. | 1.07e-05 | 4 | 47 | 2 | 25843706 | |
| Pubmed | 1.07e-05 | 4 | 47 | 2 | 22412158 | ||
| Pubmed | 1.07e-05 | 4 | 47 | 2 | 14734766 | ||
| Pubmed | 1.07e-05 | 4 | 47 | 2 | 23085515 | ||
| Pubmed | Functional role of Mst1/Mst2 in embryonic stem cell differentiation. | 1.07e-05 | 4 | 47 | 2 | 24224013 | |
| Pubmed | Hippo signaling is a potent in vivo growth and tumor suppressor pathway in the mammalian liver. | 1.78e-05 | 5 | 47 | 2 | 20080689 | |
| Pubmed | Mst1 regulates integrin-dependent thymocyte trafficking and antigen recognition in the thymus. | 1.78e-05 | 5 | 47 | 2 | 23033074 | |
| Pubmed | Assignment of the gene coding for hepatocyte growth factor-like protein to mouse chromosome 9. | 1.78e-05 | 5 | 47 | 2 | 1354648 | |
| Pubmed | The Nore1B/Mst1 complex restrains antigen receptor-induced proliferation of naïve T cells. | 1.78e-05 | 5 | 47 | 2 | 19073936 | |
| Pubmed | 1.78e-05 | 5 | 47 | 2 | 22056776 | ||
| Pubmed | 1.78e-05 | 5 | 47 | 2 | 29674007 | ||
| Pubmed | Mst1-Deficiency Induces Hyperactivation of Monocyte-Derived Dendritic Cells via Akt1/c-myc Pathway. | 1.78e-05 | 5 | 47 | 2 | 31572367 | |
| Pubmed | Tubule-Specific Mst1/2 Deficiency Induces CKD via YAP and Non-YAP Mechanisms. | 1.78e-05 | 5 | 47 | 2 | 32253273 | |
| Pubmed | 1.78e-05 | 5 | 47 | 2 | 12359736 | ||
| Pubmed | 1.78e-05 | 5 | 47 | 2 | 36646002 | ||
| Pubmed | A single transcription factor is sufficient to induce and maintain secretory cell architecture. | 1.78e-05 | 5 | 47 | 2 | 28174210 | |
| Pubmed | Daxx mediates activation-induced cell death in microglia by triggering MST1 signalling. | 2.67e-05 | 6 | 47 | 2 | 21572393 | |
| Pubmed | 2.67e-05 | 6 | 47 | 2 | 31815665 | ||
| Pubmed | Mst1-FoxO signaling protects Naïve T lymphocytes from cellular oxidative stress in mice. | 2.67e-05 | 6 | 47 | 2 | 19956688 | |
| Pubmed | 2.67e-05 | 6 | 47 | 2 | 32929029 | ||
| Pubmed | 2.67e-05 | 6 | 47 | 2 | 8325648 | ||
| Pubmed | Mst1 promotes cardiac myocyte apoptosis through phosphorylation and inhibition of Bcl-xL. | 2.67e-05 | 6 | 47 | 2 | 24813943 | |
| Pubmed | SETD4 cells contribute to brain development and maintain adult stem cell reservoir for neurogenesis. | 3.74e-05 | 7 | 47 | 2 | 36027907 | |
| Pubmed | 3.74e-05 | 7 | 47 | 2 | 27701149 | ||
| Pubmed | MOBKL1A/MOBKL1B phosphorylation by MST1 and MST2 inhibits cell proliferation. | 3.74e-05 | 7 | 47 | 2 | 18328708 | |
| Pubmed | 4.98e-05 | 8 | 47 | 2 | 19996280 | ||
| Pubmed | HIV-1 capsids bind and exploit the kinesin-1 adaptor FEZ1 for inward movement to the nucleus. | 4.98e-05 | 8 | 47 | 2 | 25818806 | |
| Pubmed | Exploiting Expression of Hippo Effector, Yap, for Expansion of Functional Islet Mass. | 7.99e-05 | 10 | 47 | 2 | 26378466 | |
| Pubmed | Mst1 inhibits autophagy by promoting the interaction between Beclin1 and Bcl-2. | 9.75e-05 | 11 | 47 | 2 | 24141421 | |
| Cytoband | 3p22.1 | 7.81e-04 | 40 | 47 | 2 | 3p22.1 | |
| Cytoband | Ensembl 112 genes in cytogenetic band chr3p22 | 9.02e-04 | 184 | 47 | 3 | chr3p22 | |
| Cytoband | 1q42.13 | 1.17e-03 | 49 | 47 | 2 | 1q42.13 | |
| Cytoband | 14q32.31 | 2.17e-03 | 67 | 47 | 2 | 14q32.31 | |
| Cytoband | 22q13.1 | 3.47e-03 | 85 | 47 | 2 | 22q13.1 | |
| Cytoband | Ensembl 112 genes in cytogenetic band chr9q34 | 4.53e-03 | 325 | 47 | 3 | chr9q34 | |
| Cytoband | 9q34.3 | 5.33e-03 | 106 | 47 | 2 | 9q34.3 | |
| GeneFamily | WD repeat domain containing | 1.18e-05 | 262 | 36 | 6 | 362 | |
| Coexpression | GSE45365_HEALTHY_VS_MCMV_INFECTION_CD11B_DC_UP | 1.99e-05 | 189 | 46 | 5 | M9978 | |
| Coexpression | DESCARTES_FETAL_CEREBELLUM_UNIPOLAR_BRUSH_CELLS | 2.66e-05 | 33 | 46 | 3 | M40161 | |
| Coexpression | MARSON_BOUND_BY_FOXP3_UNSTIMULATED | ZER1 UBA3 NDOR1 PPP2R5C HERC1 RHBDF1 LRP10 PPWD1 WDR26 ZKSCAN5 | 4.62e-05 | 1239 | 46 | 10 | M1743 |
| Coexpression | MARSON_BOUND_BY_FOXP3_UNSTIMULATED | ZER1 UBA3 NDOR1 PPP2R5C HERC1 RHBDF1 LRP10 PPWD1 WDR26 ZKSCAN5 | 5.95e-05 | 1277 | 46 | 10 | MM1032 |
| ToppCell | E18.5-Epithelial-Epithelial_Airway-Neurosecretory-Secretory-Secretory_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif | 1.04e-06 | 172 | 47 | 5 | 1bbf5ed7d13635f9a7e528060341e0652699bd7c | |
| Disease | eotaxin measurement | 2.68e-04 | 80 | 46 | 3 | EFO_0008122 | |
| Disease | inflammatory bowel disease (implicated_via_orthology) | 6.97e-04 | 25 | 46 | 2 | DOID:0050589 (implicated_via_orthology) | |
| Disease | HbA1c measurement | 3.90e-03 | 675 | 46 | 5 | EFO_0004541 | |
| Disease | neutrophil count | 5.26e-03 | 1382 | 46 | 7 | EFO_0004833 | |
| Disease | Retinitis pigmentosa | 5.98e-03 | 74 | 46 | 2 | cv:C0035334 |
| Peptide | Gene | Start | Entry |
|---|---|---|---|
| YPPGDVDEIPEWVHQ | 156 | Q6P6C2 | |
| FHPEEPEVLAVLDWE | 471 | Q6JQN1 | |
| EEDEPTLEAAWPHLQ | 121 | Q13362 | |
| VDIDAPDVDVHGPDW | 731 | Q09666 | |
| IDVPDVEVQGPDWHL | 861 | Q09666 | |
| IDAPDVEVHDPDWHL | 1696 | Q09666 | |
| DIDAPDVDVHGPDWH | 2031 | Q09666 | |
| DIDAPDVDVHGPDWH | 2226 | Q09666 | |
| DIDVPDVDVQGPDWH | 4171 | Q09666 | |
| IDVPDVDVQGPDWHL | 4636 | Q09666 | |
| WAQNVVPEAEGEDDP | 111 | A6NED2 | |
| EDGHWVPIPEEESLQ | 361 | Q86UR1 | |
| LAEPGVWVAEAEDEP | 696 | Q7Z4F1 | |
| VVPGPWQEDVADAEE | 46 | Q2TV78 | |
| WMIEHPGHEDEEEPQ | 2791 | Q15751 | |
| EDAPHEPDGVALVWN | 311 | O14576 | |
| NATEEVWIPGEGHPE | 1001 | P48681 | |
| QDHEDENEEGGEVPW | 876 | O43896 | |
| WGPREEPAHLEAAEE | 1786 | Q9UMN6 | |
| VPSVQDNDPIPWEHE | 396 | Q8TDV0 | |
| DNDPIPWEHEDQETG | 401 | Q8TDV0 | |
| PIHNWEPEEEPHKEE | 801 | P53708 | |
| DDQHELGPDAAVDPW | 131 | Q9UHB4 | |
| DEGPAEPEEPADWQT | 5036 | Q5VST9 | |
| WAPDVQHLSDPDEDQ | 371 | Q9UFP1 | |
| EQEDWAEEDEIPFPG | 966 | Q8TF40 | |
| WPPADDDDPAADQHH | 1536 | Q8IZJ3 | |
| AGEWEPAAQPPEEEA | 186 | O95931 | |
| QPGWRDHGAEFPDEE | 561 | A6NGE4 | |
| WDHDLNPEREIEVPD | 536 | Q9HC35 | |
| VVPGPWQEDVADAEE | 41 | P26927 | |
| PVPCGHQDWSEEEEG | 556 | A6NGG8 | |
| ENDEENEERWVGPLP | 41 | Q96BP3 | |
| DEPSSEDPHEWPEDI | 556 | Q96CC6 | |
| EEIENHPWLQGVDPS | 261 | Q9NRH2 | |
| HVVYPVPGNLEEEEW | 176 | Q8TAQ2 | |
| VPEQESHSQPEGWAE | 1621 | Q9H2D6 | |
| LEEVEPPWEDAHQDV | 306 | Q14028 | |
| EGVPLDGDDPEHIQW | 266 | Q8TBC4 | |
| PEAWGVCEPQREEVE | 646 | Q7Z7L7 | |
| HPGGPEAEVWEETDV | 391 | Q5TCY1 | |
| WHDEDGAVPEGCPTE | 291 | Q96K62 | |
| EEEAREEEGPWPLHE | 211 | Q9H0U9 | |
| EVDCWDGPDGEPIVH | 371 | O75038 | |
| AAMPHPEDLEDEWEV | 1396 | O15040 | |
| ETVLEGQEPPHFWEA | 576 | O15195 | |
| LAEVAEEENEPPGLW | 256 | A6NFI3 | |
| DAPELPEGHLEDWLE | 101 | Q9UDW3 | |
| EEGEAEIQEHGPEHW | 6 | Q14CZ0 | |
| WGPAPFIDHQNIEEE | 641 | Q9H7D7 | |
| PEEVAEWLHLDDDGG | 526 | Q53EQ6 | |
| PEIHQTPDWEIVFED | 346 | O95125 | |
| EGIHVLDWPFDDGAP | 61 | Q93096 | |
| FQPWVREHHPESGEE | 106 | Q9Y2L8 | |
| PPDSEDCGEEQTRWH | 331 | Q8TEU8 |