Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionguanyl-nucleotide exchange factor activity

DOCK2 TBC1D10A DENND4C DENND4A

2.85e-05231164GO:0005085
GeneOntologyMolecularFunctionGTPase regulator activity

DOCK2 TBC1D10A DENND4C DENND4A

5.86e-04507164GO:0030695
GeneOntologyMolecularFunctionnucleoside-triphosphatase regulator activity

DOCK2 TBC1D10A DENND4C DENND4A

5.86e-04507164GO:0060589
GeneOntologyMolecularFunctionenzyme regulator activity

DOCK2 TBC1D10A DENND4C DENND4A ERCC6

4.04e-031418165GO:0030234
GeneOntologyMolecularFunctionmetalloendopeptidase activity

ADAM28 ADAM32

4.07e-03120162GO:0004222
GeneOntologyBiologicalProcessregulation of Rab protein signal transduction

DENND4C DENND4A

8.45e-066162GO:0032483
GeneOntologyBiologicalProcessRab protein signal transduction

DENND4C DENND4A

1.17e-0421162GO:0032482
DomainPPR

DENND4C DENND4A

4.12e-064162PF01535
DomainPPR

DENND4C DENND4A

1.92e-058162PS51375
DomainDENN

DENND4C DENND4A

8.20e-0516162PF02141
DomainUDENN

DENND4C DENND4A

8.20e-0516162PS50946
DomainDDENN

DENND4C DENND4A

8.20e-0516162PS50947
DomaindDENN_dom

DENND4C DENND4A

8.20e-0516162IPR005112
DomainuDENN_dom

DENND4C DENND4A

8.20e-0516162IPR005113
DomaindDENN

DENND4C DENND4A

8.20e-0516162PF03455
DomainDENN

DENND4C DENND4A

8.20e-0516162SM00799
DomainDENN

DENND4C DENND4A

8.20e-0516162PS50211
DomaindDENN

DENND4C DENND4A

8.20e-0516162SM00801
DomainDENN_dom

DENND4C DENND4A

8.20e-0516162IPR001194
DomainDisintegrin_CS

ADAM28 ADAM32

8.20e-0516162IPR018358
DomainADAM_CR

ADAM28 ADAM32

1.04e-0418162PF08516
Domain-

ADAM28 ADAM32

1.30e-04201624.10.70.10
DomainDISIN

ADAM28 ADAM32

1.43e-0421162SM00050
DomainDisintegrin

ADAM28 ADAM32

1.43e-0421162PF00200
DomainPentatricopeptide_repeat

DENND4C DENND4A

1.72e-0423162IPR002885
DomainADAM_Cys-rich

ADAM28 ADAM32

2.39e-0427162IPR006586
DomainACR

ADAM28 ADAM32

2.39e-0427162SM00608
DomainPep_M12B_propep

ADAM28 ADAM32

5.01e-0439162PF01562
DomainPeptidase_M12B_N

ADAM28 ADAM32

5.01e-0439162IPR002870
DomainDISINTEGRIN_1

ADAM28 ADAM32

5.27e-0440162PS00427
DomainReprolysin

ADAM28 ADAM32

5.27e-0440162PF01421
DomainADAM_MEPRO

ADAM28 ADAM32

5.27e-0440162PS50215
DomainDISINTEGRIN_2

ADAM28 ADAM32

5.27e-0440162PS50214
DomainPeptidase_M12B

ADAM28 ADAM32

5.27e-0440162IPR001590
DomainDisintegrin_dom

ADAM28 ADAM32

5.53e-0441162IPR001762
Domain-

ADAM28 ADAM32

2.14e-03811623.40.390.10
DomainMetalloPept_cat_dom

ADAM28 ADAM32

2.14e-0381162IPR024079
DomainEGF

ADAM28 ADAM32

1.68e-02235162SM00181
DomainEGF_3

ADAM28 ADAM32

1.68e-02235162PS50026
DomainEGF-like_dom

ADAM28 ADAM32

1.88e-02249162IPR000742
DomainEGF_1

ADAM28 ADAM32

1.96e-02255162PS00022
DomainEGF-like_CS

ADAM28 ADAM32

2.05e-02261162IPR013032
DomainEGF_2

ADAM28 ADAM32

2.11e-02265162PS01186
DomainARM-like

SCYL2 DOCK2

2.19e-02270162IPR011989
PathwayREACTOME_RAB_REGULATION_OF_TRAFFICKING

TBC1D10A DENND4C DENND4A

6.57e-05118103MM15589
PathwayREACTOME_RAB_REGULATION_OF_TRAFFICKING

TBC1D10A DENND4C DENND4A

7.26e-05122103M27872
Pubmed

The role of ESCO2, SALL4 and TBX5 genes in the susceptibility to thalidomide teratogenesis.

ESCO2 SALL4

5.95e-07316231388035
Pubmed

Molecular cloning, structural analysis, and expression of a human IRLB, MYC promoter-binding protein: new DENN domain-containing protein family emerges.

DENND4C DENND4A

5.95e-07316212906859
Pubmed

Family-wide characterization of the DENN domain Rab GDP-GTP exchange factors.

DENND4C DENND4A

1.31e-043716220937701
Pubmed

A protein interaction network for pluripotency of embryonic stem cells.

ZMYM2 SALL4

1.61e-044116217093407
CytobandEnsembl 112 genes in cytogenetic band chr8p21

ESCO2 ADAM28

1.00e-03135162chr8p21
GeneFamilyGuanylate cyclase receptors|DENN/MADD domain containing

DENND4C DENND4A

8.20e-0525102504
GeneFamilyADAM metallopeptidase domain containing|CD molecules

ADAM28 ADAM32

9.59e-052710247
CoexpressionGSE40225_WT_VS_RIP_B7X_DIABETIC_MOUSE_PANCREATIC_CD8_TCELL_UP

DOCK2 TBC1D10A ADAM28 DENND4C

5.46e-06199164M9238
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ESCO2 DOCK2 HASPIN

2.81e-0516916354b13ab02b4c187f4754045ecfcf409749e7ccc0
ToppCellfacs-Marrow-T-cells-3m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ESCO2 SCYL2 HASPIN

2.91e-05171163f28b2336057e353b96a6ff4581ec9fd0ca0789d9
ToppCellfacs-Marrow-T-cells-3m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ESCO2 SCYL2 HASPIN

2.91e-05171163913bae728b5e653771a27c79a309eb023699f1d0
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_B-plasmablast-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

ESCO2 ERCC6 HASPIN

3.34e-05179163021d782134126c6f7dce6b6ea50cc54bdaa39987
ToppCellEntopeduncular-Macroglia-POLYDENDROCYTE-P3-Tnr|Entopeduncular / BrainAtlas - Mouse McCarroll V32

ESCO2 HASPIN

6.83e-04109162e3696d84da1dcd15f15d0434ea9d1955f2af22d6
ToppCellEntopeduncular-Macroglia-POLYDENDROCYTE-P3-Tnr-Polydendendrocytes_NG2_cells_(Tnr-Cspg5)-|Entopeduncular / BrainAtlas - Mouse McCarroll V32

ESCO2 HASPIN

6.83e-041091626678036ff66c825a18d2506e33be421c27cf82e1
ToppCellEntopeduncular-Macroglia-POLYDENDROCYTE-P3-Tnr-Polydendendrocytes_NG2_cells_(Tnr-Cspg5)|Entopeduncular / BrainAtlas - Mouse McCarroll V32

ESCO2 HASPIN

6.83e-0410916287f647cfebbb7de725e434cc27058e1c6accbb90
ToppCellEntopeduncular-Macroglia-POLYDENDROCYTE-P3|Entopeduncular / BrainAtlas - Mouse McCarroll V32

ESCO2 HASPIN

6.83e-04109162c9d1e69f9841135f4d114563a293a69a8ba5f965
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Mucinous_Adenocarcinoma|TCGA-Lung / Sample_Type by Project: Shred V9

FSIP2 ADAM28

8.96e-04125162b82ce58b6262b0739c788395766e5fc77d2744f2
ToppCellHippocampus-Macroglia-POLYDENDROCYTE-P5-P5_1-Sox4-POLYDENDROCYTE_(Neurogenesis.Sox4.Hist1h2al)|Hippocampus / BrainAtlas - Mouse McCarroll V32

ESCO2 HASPIN

9.10e-041261626072996987f7b05949adb86c9433e3302c4441d2
ToppCell5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-immature_mesenchymal_cell-Mesoderm_1_(HAND1+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ESCO2 ADAM28

9.39e-041281629ab55a0421cd970e0b8dabce67dd68e382a6bd41
ToppCellprimary_visual_cortex-Non-neuronal-oligodendrocyte-Oligo-OPC_Pdgfra_Ccnb1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ESCO2 HASPIN

9.53e-04129162ff74d159034a09f7b174da18bfb9a26936252b4c
ToppCelldroplet-Tongue-Unstain-18m-Epithelial-nan|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCYL2 CSDC2

1.01e-03133162f7d0763b5eec2db33044d6850fd57462494038c1
ToppCellFrontal_cortex-Macroglia-POLYDENDROCYTE-P4-Tnr|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

ESCO2 HASPIN

1.15e-031421627bd05d0c0ac2dee0e6cc0f3c531f9154bf300c75
ToppCellFrontal_cortex-Macroglia-POLYDENDROCYTE-P4-Tnr-Polydendrocyte.Tnr.Dlx1_(Dlx1)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

ESCO2 HASPIN

1.15e-0314216292bf826827b3e3387ad326566556fc90c5c2f4d5
ToppCellFrontal_cortex-Macroglia-POLYDENDROCYTE-P4|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

ESCO2 HASPIN

1.15e-03142162328d08ba2712cd42bb9846ac4d7453ae165b75e2
ToppCellFrontal_cortex-Macroglia-POLYDENDROCYTE-P4-Tnr-Polydendrocyte.Tnr.Dlx1_(Dlx1)-|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

ESCO2 HASPIN

1.15e-0314216294774d3e598d074f48146b0b094705dc48af5a1f
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

ADAM28 ADAM32

1.20e-03145162b17699f7f98d2361a4d26c26f52db05e7ff69dff
ToppCell15-Trachea-Immune-Immune|Trachea / Age, Tissue, Lineage and Cell class

ESCO2 DOCK2

1.22e-03146162ca722a89c6601e78f253d9484d01931f26161820
ToppCellMild/Remission-B_naive-4|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

ADAM28 DENND4A

1.25e-03148162dd5e1bc02824e743e1c030a303e32f27a359a8ca
ToppCellHippocampus-Macroglia-POLYDENDROCYTE-P5-P5_1|Hippocampus / BrainAtlas - Mouse McCarroll V32

ESCO2 HASPIN

1.25e-03148162b9d3421c2eb8e748e9508c1cbd1cb4f96e23db5a
ToppCellHippocampus-Macroglia-POLYDENDROCYTE-P5-P5_1-Sox4|Hippocampus / BrainAtlas - Mouse McCarroll V32

ESCO2 HASPIN

1.25e-031481622a7671dc27afbdf6a92d976c5f2b728bd18dd609
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-Classical_Dendritic_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK2 ADAM28

1.25e-0314816212fa2c4922f03803006c606b1b16e79441e3bb13
ToppCell3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SALL4 ADAM28

1.27e-03149162aedbae2dffa1e880e5c6a146b6d5a135e7f54308
ToppCell368C-Fibroblasts-Fibroblast-E|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

ERCC6 HASPIN

1.28e-03150162c3ad5fa41eb636a5d691c0268c0f1c32cd0de658
ToppCell368C-Fibroblasts-Fibroblast-E-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

ERCC6 HASPIN

1.28e-0315016278b8029e71d26f336a46274c8afef3435bf536b9
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Macrophage-macrophage,_alveolar-Macro_c2-CCL3L1|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

DOCK2 DENND4A

1.32e-0315216218194f757d319958f26e5a91f56d89f25711236f
ToppCellPosterior_cortex-Macroglia-POLYDENDROCYTE-P4-Tnr|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

ESCO2 HASPIN

1.34e-0315316254a941950bbb848077c7bd5726da9e4b3244bd38
ToppCellPosterior_cortex-Macroglia-POLYDENDROCYTE-P4-Tnr-Polydendrocyte.Tnr.Dlx1_(Dlx1)-|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

ESCO2 HASPIN

1.34e-03153162d7635f3d4831c02a94f53afc674847d5b51453be
ToppCellPosterior_cortex-Macroglia-POLYDENDROCYTE-P4|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

ESCO2 HASPIN

1.34e-0315316269a8550418ba0fc908a84b3b85761abb6e8ca4c0
ToppCellPosterior_cortex-Macroglia-POLYDENDROCYTE-P4-Tnr-Polydendrocyte.Tnr.Dlx1_(Dlx1)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

ESCO2 HASPIN

1.34e-03153162e50d20f9e553b8c3e10e187770d8abe1a43d109e
ToppCellDendritic_Cells-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

ADAM28 HASPIN

1.35e-0315416265013f696da623d37f1e3447a294dfb3c31ae93b
ToppCellFetal_29-31_weeks-Immune-dendritic_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DOCK2 ADAM28

1.37e-031551629f937ae48767fdcf1a944af4de0530d9c0ab441d
ToppCellTCGA-Kidney-Primary_Tumor-Renal_Cell_Carcinoma-Kidney_Clear_Cell_Renal_Carcinoma-6|TCGA-Kidney / Sample_Type by Project: Shred V9

ESCO2 HASPIN

1.39e-03156162d249747c7108a0edfc72d24c09b0b0e4ed662b40
ToppCellCOVID-19-Myeloid-Dendritic_cells|COVID-19 / group, cell type (main and fine annotations)

DOCK2 ADAM28

1.39e-03156162a07a9096799e4ba663841c70035b4b32c1fda4f9
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Immune-Lymphocytic_B|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK2 SALL4

1.42e-031581622cfa6dd36c8ae534cf1dd49366d4b4433388c1e0
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Immune-Lymphocytic_B-Plasma_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK2 SALL4

1.42e-03158162cebb58878b6945074bc1c7d5848d842da5dcbae1
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Immune-Lymphocytic_B-Plasma_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK2 SALL4

1.42e-031581620c9bb7f8d080a052ca71701544a076c6c2ea67cd
ToppCellPBMC-Severe-Lymphocyte-B-B_cell-B_naive-B_naive-5|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

FSIP2 ADAM28

1.42e-0315816241cf950983f47a9e55d56041b301006b42853b37
ToppCellE18.5-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DOCK2 DENND4A

1.46e-031601624a0ae0a83a10dbfc13591f4d2228ba8bcd2c2275
ToppCellCOVID-19-kidney-Plasma|COVID-19 / Disease (COVID-19 only), tissue and cell type

DOCK2 ADAM28

1.46e-03160162f8d9e459976e711e9ad39ea2b6173140c0589d6e
ToppCellGlobus_pallidus-Macroglia-POLYDENDROCYTE-P5|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

ESCO2 HASPIN

1.48e-03161162efb811dda4d73107983a5f68302bdcf4f408d5b4
ToppCellGlobus_pallidus-Macroglia-POLYDENDROCYTE-P5-P5_1|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

ESCO2 HASPIN

1.48e-031611620dd1401b4c990d49fccb702a9f9867590a58e203
ToppCellGlobus_pallidus-Macroglia-POLYDENDROCYTE-P5-P5_1-Mitotic.MkI67_(Mitotic.MkI67)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

ESCO2 HASPIN

1.48e-0316116228d5dbd20c9f8e0069f172d552997a044790e1a7
ToppCellGlobus_pallidus-Macroglia-POLYDENDROCYTE-P5-P5_1-Mitotic.MkI67_(Mitotic.MkI67)-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

ESCO2 HASPIN

1.48e-03161162b6a31c033edc74f23a20aab1f18e80cc83ffee4c
ToppCell368C-Fibroblasts-Fibroblast-E|368C / Donor, Lineage, Cell class and subclass (all cells)

ERCC6 HASPIN

1.50e-03162162e17632778a57c71d6005d3abca3a0443a92040e7
ToppCell368C-Fibroblasts-Fibroblast-E-|368C / Donor, Lineage, Cell class and subclass (all cells)

ERCC6 HASPIN

1.50e-03162162ac4a80fd72c9311ea2b3e574c6284bbce4f2756c
ToppCellfacs-Kidney-nan-3m-Lymphocytic-T_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK2 DENND4A

1.51e-031631628004cc0b3428be08b89957b563cd8799f822d931
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

ADAM28 DENND4A

1.51e-031631626bed27d2f67a430a847da5eb47878d14b4949c45
ToppCellfacs-Kidney-nan-3m-Lymphocytic-T_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK2 DENND4A

1.51e-03163162385b24e18df5ef92108483de312d6c85a1e6d145
ToppCelldroplet-Liver-nan-3m-Lymphocytic|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCYL2 ERCC6

1.53e-03164162bf0d3ad9016a0b8011a2385bb92f0a4f5edad1d6
ToppCellfacs-Liver-Non-hepatocytes-3m-Myeloid-neutrophil|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BRWD3 DENND4A

1.53e-031641628e6dbddacd56a07769163813e3ebfad13302bb62
ToppCelldroplet-Liver-nan-3m-Lymphocytic-NK/T|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCYL2 ERCC6

1.53e-03164162c33910a6d87580902e9e7bd27afe6ea63b5eff8d
ToppCelldroplet-Liver-nan-3m-Lymphocytic-NK_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCYL2 ERCC6

1.53e-03164162950f87d9dacee45c9004a9bf894543de38f72ee5
ToppCell390C-Myeloid-Dendritic-cDC_proliferating_2|390C / Donor, Lineage, Cell class and subclass (all cells)

ESCO2 HASPIN

1.53e-03164162ad508f53009efdd1dae7abcdb5431387f3f7e7b2
ToppCellPND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_G2M|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ESCO2 HASPIN

1.53e-03164162ae09e5aabd1347b865474255e7411c04f63efb3b
ToppCellAdult-Mesenchymal-chondrocyte-D231|Adult / Lineage, Cell type, age group and donor

SALL4 CSDC2

1.53e-031641622ba57dce5f69a88f0d1e450b9780425e2d9ca7d4
ToppCellAdult-Epithelial-lung_goblet_cell-D175|Adult / Lineage, Cell type, age group and donor

SALL4 ADAM28

1.53e-031641626e6aedb61f8e195d52e028fdda750a29bb14e57e
ToppCellAdult-Mesenchymal-myofibroblast_cell-D231|Adult / Lineage, Cell type, age group and donor

CSDC2 ADAM32

1.53e-031641623d8ff70fe5582d1fb56b338be8b76fa1428b3657
ToppCellPND03-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_G2M|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ESCO2 HASPIN

1.55e-0316516226c750f10f6401752e2e63d91dc844c81b29d735
ToppCellFetal_29-31_weeks-Immune-dendritic_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DOCK2 ADAM28

1.55e-03165162d8b0a9b6f704b98e8f0412c11739879a26c036e2
ToppCellAdult-Immune-dendritic_cell|Adult / Lineage, Cell type, age group and donor

ADAM28 HASPIN

1.55e-03165162073f52698dac1fe4edd7410865f81b30e1c7196a
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_B-B_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK2 ADAM28

1.55e-031651627039bb5a7af4684fbd1192230864e5cd6936e83c
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_B-B_Cell-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK2 ADAM28

1.55e-03165162d2c79653710b139794170f3d72f11392fc548ac7
ToppCell390C-Myeloid-Dendritic-cDC_proliferating_2|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

ESCO2 HASPIN

1.55e-03165162a5c3af634d2698f9a01cf074791756b7669f9fff
ToppCellmild_COVID-19_(asymptomatic)-Plasmablast|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)

ESCO2 HASPIN

1.57e-031661620cc3b9681bc000a1b00d3b60f79f16eea1c2e2e1
ToppCellDividing_Macrophages-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

ESCO2 HASPIN

1.57e-03166162c503036f3c19ef186e1e62c9643c49dea3827f51
ToppCell5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SALL4 ADAM28

1.57e-031661623b67064a5149e72f895344d938c64b8ff65247f5
ToppCelldroplet-Lung-nan-21m-Lymphocytic-Proliferating_NK|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ESCO2 HASPIN

1.57e-0316616221ba5fd755c0fb31ada42a1b5d60bede0153323d
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Macrophage_Dendritic-Classical_Dendritic_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ESCO2 ADAM28

1.57e-0316616263dc58864268b4e7779e4c45155022556fc634f9
ToppCellDividing_Macrophages-Donor_06|World / lung cells shred on cell class, cell subclass, sample id

ESCO2 HASPIN

1.57e-03166162ea95b94ccc2ac67df741b30c27f4ae698925875f
ToppCelldroplet-Fat-Bat-18m-Myeloid-myeloid_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCYL2 ADAM28

1.61e-03168162794035cb63353a7d02fd9939deb5b4d075c9d95a
ToppCellControl-B_cells-Activated_B_cells|Control / group, cell type (main and fine annotations)

DOCK2 ADAM28

1.61e-03168162a7159a35fe37f8c241cf8d391debe271e0698105
ToppCelldroplet-Trachea-3m-Hematologic-myeloid-granulocyte-granulocyte_l34|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DOCK2 DENND4A

1.61e-0316816284977db9d71e59208727885320cc18d80d064380
ToppCelldroplet-Fat-Bat-18m-Myeloid-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCYL2 ADAM28

1.61e-031681626fddc957a0503455d8c165862b5eb8e5fdb8a510
ToppCelldroplet-Fat-Bat-18m-Myeloid|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCYL2 ADAM28

1.61e-031681621e23b634f96e88b976a523ca1f3fc08f6fe9b239
ToppCellPND10-Immune-Immune_Myeloid-DC-cDC2-cDC2_G2M|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DCP2 HASPIN

1.61e-031681624c402a1613fcf0a6e4d9b9d5551812940e91ff32
ToppCellMild/Remission-B_naive-4|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)

ADAM28 DENND4A

1.63e-03169162c3a6179a64589a370108fea809b157839347759c
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Monocytic|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK2 ADAM28

1.63e-03169162b2fdf9f842dc7c181bc951a8a6932c916ed835ef
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Monocytic-Monocyte-derived_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK2 ADAM28

1.63e-031691622322f03a115c662f808ebfc892192b7d38d48181
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-FOXM1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ESCO2 HASPIN

1.63e-03169162e0607af8ae8609d43e26ff2a2cab92650bfcd5b7
ToppCellPND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_G2M|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ESCO2 HASPIN

1.64e-031701626b91d4cbe0697b65bfb2e099e7a9b39ea2fba3a9
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_B|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK2 ADAM28

1.64e-03170162a965e3ee6818790a4a6916824fde64333d9b11b7
ToppCellCOVID-19-kidney-Plasma|kidney / Disease (COVID-19 only), tissue and cell type

DOCK2 ADAM28

1.66e-03171162a59a054b8e119215f24dc5c80ad5a8094b3500f9
ToppCellImmune-dendritic_cell|World / Lineage, Cell type, age group and donor

DOCK2 ADAM28

1.66e-031711626a9e2e2d3e1d8cc475bf9765129bc4a32da3b8ea
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ESCO2 DOCK2

1.66e-0317116255c7bf7211587fa08df13c0a4ff5b78a85d5439e
ToppCellCOVID-19-kidney-Bcells|COVID-19 / Disease (COVID-19 only), tissue and cell type

DOCK2 ADAM28

1.66e-031711628e8fb79968b1a5c34d1d9cad7f9155fabfdb7cc7
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-Stromal_1_(CCL11+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAM28 ADAM32

1.68e-03172162afa36501d48b1456c511fa0d5d326ec05bdc380f
ToppCelldroplet-Trachea-nan-3m-Myeloid-macrophage|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK2 DENND4A

1.68e-03172162f6c00a6a7e81aaf96c55eb3a3c88e3719f102ea0
ToppCellPND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_G2M|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ESCO2 HASPIN

1.68e-03172162dd9ba79e1542fe9fa2c319077d83dd3fc0158f46
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ESCO2 DOCK2

1.68e-03172162ef33b5e0515c6d29fb6d9a673011c1b68ef264f3
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Monocytic-Monocyte-derived_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK2 ADAM28

1.68e-03172162f6b4754a7e4b3e38030316a0ae00d932bfa87e41
ToppCelldroplet-Trachea-3m-Hematologic-myeloid-tracheal_macrophage|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DOCK2 DENND4A

1.68e-03172162f3bbe3f069ad070778430d1a6cd9db0a76deb8de
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_B|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK2 ADAM28

1.70e-0317316262ba49c1c16760a8c6cde0cc44e068f94386946a
ToppCell10x5'-bone_marrow-Lymphocytic_NK-Cycling_NK|bone_marrow / Manually curated celltypes from each tissue

ESCO2 HASPIN

1.70e-031731628a9dd85f718564c07cf3120ad648daeb60c94fc5
ToppCelldroplet-Large_Intestine-COLON:P+D-30m-Hematologic-hematopoietic_stem_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK2 DENND4A

1.70e-031731627456a417c5c1d4ba25f9489065aae322421308a6
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B-B_cell|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

ADAM28 DENND4A

1.70e-03173162d56e337eae727a29cd53cfd628e1b3c0a98e1f51
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-Classical_Dendritic_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK2 ADAM28

1.70e-0317316273f858f2c45d19b9ec8d99ac02c91551790f670c
ToppCelldroplet-Large_Intestine-COLON:P+D-30m-Hematologic-hematopoietic_stem_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK2 DENND4A

1.70e-0317316235586a9e5f15b41609b6224e33eb3aa3cb7e03b7
ToppCelldroplet-Large_Intestine-COLON:P+D-30m-Hematologic|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK2 DENND4A

1.70e-03173162cd635751f999e12b14c0accfa1c4c1fd3c1d4540
Diseaselung cancer (is_marker_for)

ESCO2 ERCC6

2.02e-0439162DOID:1324 (is_marker_for)
Diseaselung adenocarcinoma (is_implicated_in)

ESCO2 ADAM28

3.19e-0449162DOID:3910 (is_implicated_in)
Diseaselung adenocarcinoma (is_marker_for)

ADAM28 ERCC6

9.59e-0485162DOID:3910 (is_marker_for)
Diseasehearing impairment

SALL4 ERCC6

1.27e-0398162C1384666
Diseaseneuroblastoma

DOCK2 SALL4

1.77e-03116162EFO_0000621
Diseaselung non-small cell carcinoma (is_implicated_in)

ADAM28 ERCC6

2.53e-03139162DOID:3908 (is_implicated_in)
DiseaseCraniofacial Abnormalities

SALL4 ERCC6

3.17e-03156162C0376634
Diseasecolorectal cancer (is_marker_for)

ADAM28 ERCC6

3.21e-03157162DOID:9256 (is_marker_for)

Protein segments in the cluster

PeptideGeneStartEntry
KQKRKPQMVKAVQPQ

ADAM28

711

Q9UKQ2
SPKGKQKQMKLQPKN

BRWD3

1466

Q6RI45
VKCLQNKPQMQKKSP

ADAM32

376

Q8TC27
NKPQMQKKSPKPVCG

ADAM32

381

Q8TC27
PAKQQNSLMKCEKKL

DCP2

341

Q8IU60
KILPKKPCKNLMNTL

DENND4A

506

Q7Z401
SQKLKKKIQVQQPNM

ERCC6

906

P0DP91
QQKLLNKKMLPKLQP

FSIP2

3031

Q5CZC0
IPPVKLQKQKVQSMN

DOCK2

826

Q92608
KNMNWKQLPKKPCKN

DENND4C

501

Q5VZ89
MQGKPVCSKKNNKKP

ESCO2

126

Q56NI9
KCNTPAMKQIKRKIQ

HASPIN

761

Q8TF76
KMCPIPPKNQKFQAV

CSDC2

116

Q9Y534
KKNCTKNPPVLIMND

SALL4

91

Q9UJQ4
PQKPKVSMNQLSQQK

SCYL2

846

Q6P3W7
PNKEMKNKAVLCKPL

ZMYM2

841

Q9UBW7
KPPKQAQKEQRKQMK

TBC1D10A

426

Q9BXI6