Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	lysine-acetylated histone binding	POU5F1 POU5F1B BAZ2A	2.91e-05	30	40	3	GO:0070577
GeneOntologyMolecularFunction	acetylation-dependent protein binding	POU5F1 POU5F1B BAZ2A	3.22e-05	31	40	3	GO:0140033
GeneOntologyMolecularFunction	POU domain binding	POU5F1 POU5F1B	8.16e-05	7	40	2	GO:0070974
GeneOntologyMolecularFunction	RNA polymerase II-specific DNA-binding transcription factor binding	POU5F1 CHD4 POU5F1B TRIB2 PER2 BAZ2A	1.68e-04	417	40	6	GO:0061629
GeneOntologyMolecularFunction	RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding	POU5F1 POU5F1B	3.01e-04	13	40	2	GO:0001162
GeneOntologyMolecularFunction	intronic transcription regulatory region sequence-specific DNA binding	POU5F1 POU5F1B	5.22e-04	17	40	2	GO:0001161
GeneOntologyMolecularFunction	ubiquitin protein ligase binding	AURKA CUL1 POU5F1 POU5F1B TRIB2	5.39e-04	337	40	5	GO:0031625
GeneOntologyMolecularFunction	ubiquitin-like protein ligase binding	AURKA CUL1 POU5F1 POU5F1B TRIB2	7.08e-04	358	40	5	GO:0044389
GeneOntologyMolecularFunction	HMG box domain binding	POU5F1 POU5F1B	9.64e-04	23	40	2	GO:0071837
GeneOntologyMolecularFunction	DNA-binding transcription factor binding	POU5F1 CHD4 POU5F1B TRIB2 PER2 BAZ2A	9.87e-04	582	40	6	GO:0140297
GeneOntologyMolecularFunction	histone binding	POU5F1 CHD4 POU5F1B BAZ2A	1.90e-03	265	40	4	GO:0042393
GeneOntologyBiologicalProcess	trophectodermal cell fate commitment	POU5F1 POU5F1B	1.10e-05	3	40	2	GO:0001830
GeneOntologyBiologicalProcess	negative regulation of regulated secretory pathway	POU5F1 POU5F1B ABR	3.22e-05	32	40	3	GO:1903306
GeneOntologyBiologicalProcess	ectodermal cell fate commitment	POU5F1 POU5F1B	3.65e-05	5	40	2	GO:0001712
GeneOntologyBiologicalProcess	endodermal cell differentiation	POU5F1 POU5F1B ITGAV	5.44e-05	38	40	3	GO:0035987
GeneOntologyBiologicalProcess	ectoderm formation	POU5F1 POU5F1B	7.65e-05	7	40	2	GO:0001705
GeneOntologyBiologicalProcess	negative regulation of exocytosis	POU5F1 POU5F1B ABR	9.06e-05	45	40	3	GO:0045920
GeneOntologyBiologicalProcess	endoderm formation	POU5F1 POU5F1B ITGAV	1.17e-04	49	40	3	GO:0001706
GeneOntologyBiologicalProcess	ectodermal cell differentiation	POU5F1 POU5F1B	1.31e-04	9	40	2	GO:0010668
GeneOntologyBiologicalProcess	germ-line stem cell population maintenance	POU5F1 POU5F1B	1.63e-04	10	40	2	GO:0030718
GeneOntologyBiologicalProcess	endodermal cell fate specification	POU5F1 POU5F1B	1.99e-04	11	40	2	GO:0001714
GeneOntologyBiologicalProcess	negative regulation of calcium ion-dependent exocytosis	POU5F1 POU5F1B	1.99e-04	11	40	2	GO:0045955
GeneOntologyBiologicalProcess	ubiquitin-dependent protein catabolic process	AURKA CUL1 TRIB2 CHMP6 DCST1 UBE3B WAC	2.05e-04	640	40	7	GO:0006511
GeneOntologyBiologicalProcess	modification-dependent protein catabolic process	AURKA CUL1 TRIB2 CHMP6 DCST1 UBE3B WAC	2.27e-04	651	40	7	GO:0019941
GeneOntologyBiologicalProcess	modification-dependent macromolecule catabolic process	AURKA CUL1 TRIB2 CHMP6 DCST1 UBE3B WAC	2.38e-04	656	40	7	GO:0043632
GeneOntologyCellularComponent	female germ cell nucleus	AURKA POU5F1 POU5F1B	2.81e-05	31	40	3	GO:0001674
GeneOntologyCellularComponent	microtubule associated complex	AURKA KIF9 RABGAP1 DNAH14	2.50e-04	161	40	4	GO:0005875
GeneOntologyCellularComponent	microtubule	AURKA TRPV4 KIF9 CHMP6 SPAG17 DNAH14	4.91e-04	533	40	6	GO:0005874
GeneOntologyCellularComponent	transcription repressor complex	POU5F1 POU5F1B PER2	6.15e-04	87	40	3	GO:0017053
MousePheno	abnormal blastocyst morphology	AURKA POU5F1 CHD4 POU5F1B DDX18 SNX13	2.78e-05	259	33	6	MP:0004957
MousePheno	abnormal preimplantation embryo morphology	AURKA POU5F1 CHD4 POU5F1B DDX18 SNX13	4.56e-05	283	33	6	MP:0014137
Domain	POU_dom_5	POU5F1 POU5F1B	1.27e-05	3	39	2	IPR015585
Domain	POU	POU5F1 POU5F1B	5.01e-04	16	39	2	SM00352
Domain	POU_2	POU5F1 POU5F1B	5.01e-04	16	39	2	PS00465
Domain	POU_dom	POU5F1 POU5F1B	5.01e-04	16	39	2	IPR000327
Domain	POU_3	POU5F1 POU5F1B	5.01e-04	16	39	2	PS51179
Domain	Pou	POU5F1 POU5F1B	5.01e-04	16	39	2	PF00157
Domain	POU_1	POU5F1 POU5F1B	5.01e-04	16	39	2	PS00035
Domain	POU	POU5F1 POU5F1B	5.66e-04	17	39	2	IPR013847
Domain	-	POU5F1 POU5F1B	1.44e-03	27	39	2	1.10.260.40
Domain	Lambda_DNA-bd_dom	POU5F1 POU5F1B	1.66e-03	29	39	2	IPR010982
Domain	P-loop_NTPase	GNA11 KIF9 CHD4 NLRP14 ABCD2 DNAH14 DDX18	1.67e-03	848	39	7	IPR027417
Domain	GDS_CDC24_CS	PLEKHG1 ABR	3.00e-03	39	39	2	IPR001331
Domain	-	GNA11 CHD4 NLRP14 ABCD2 DNAH14 DDX18	4.21e-03	746	39	6	3.40.50.300
Domain	Homeodomain-like	SETMAR POU5F1 RABGAP1 POU5F1B	4.94e-03	332	39	4	IPR009057
Domain	RhoGAP	OCRL ABR	7.42e-03	62	39	2	SM00324
Domain	RhoGAP	OCRL ABR	7.66e-03	63	39	2	PF00620
Domain	DH_1	PLEKHG1 ABR	7.66e-03	63	39	2	PS00741
Domain	RHOGAP	OCRL ABR	7.89e-03	64	39	2	PS50238
Domain	RhoGAP_dom	OCRL ABR	7.89e-03	64	39	2	IPR000198
Domain	-	OCRL ABR	7.89e-03	64	39	2	1.10.555.10
Domain	RhoGEF	PLEKHG1 ABR	8.87e-03	68	39	2	SM00325
Domain	RNaseH-like_dom	SETMAR POLE	9.13e-03	69	39	2	IPR012337
Domain	RhoGEF	PLEKHG1 ABR	9.38e-03	70	39	2	PF00621
Domain	DH_2	PLEKHG1 ABR	9.38e-03	70	39	2	PS50010
Domain	DH-domain	PLEKHG1 ABR	9.64e-03	71	39	2	IPR000219
Domain	-	PLEKHG1 ABR	9.64e-03	71	39	2	1.20.900.10
Pubmed	Fbx15 is a novel target of Oct3/4 but is dispensable for embryonic stem cell self-renewal and mouse development.	CUL1 POU5F1 POU5F1B	2.81e-08	6	40	3	12665572
Pubmed	Conditional Aurora A deficiency differentially affects early mouse embryo patterning.	AURKA POU5F1 POU5F1B	2.31e-07	11	40	3	22939930
Pubmed	Metastasis tumor antigen 2 (MTA2) is involved in proper imprinted expression of H19 and Peg3 during mouse preimplantation development.	POU5F1 CHD4 POU5F1B	3.08e-07	12	40	3	20720167
Pubmed	Constraint of gene expression by the chromatin remodelling protein CHD4 facilitates lineage specification.	POU5F1 CHD4 POU5F1B	7.81e-07	16	40	3	26116663
Pubmed	Genetic tool for fate mapping of Oct4 (Pou5f1)-expressing cells and their progeny past the pluripotency stage.	POU5F1 POU5F1B	1.29e-06	2	40	2	31843009
Pubmed	Characterization of novel alternative splicing variants of Oct4 gene expressed in mouse pluripotent stem cells.	POU5F1 POU5F1B	1.29e-06	2	40	2	29266259
Pubmed	Identification of mouse blastocyst genes that are downregulated by double-stranded RNA-mediated knockdown of Oct-4 expression.	POU5F1 POU5F1B	1.29e-06	2	40	2	15685634
Pubmed	Regulatory Elements Outside Established Pou5f1 Gene Boundaries Are Required for Multilineage Differentiation of Embryonic Stem Cells.	POU5F1 POU5F1B	1.29e-06	2	40	2	37895112
Pubmed	Nuclear and chromatin reorganization in the MHC-Oct3/4 locus at developmental phases of embryonic stem cell differentiation.	POU5F1 POU5F1B	1.29e-06	2	40	2	16950240
Pubmed	Maternal Oct-4 is a potential key regulator of the developmental competence of mouse oocytes.	POU5F1 POU5F1B	1.29e-06	2	40	2	18837968
Pubmed	[Investigation of transcriptional regulation of Oct4 (POU5F1) gene with distal enhancer].	POU5F1 POU5F1B	1.29e-06	2	40	2	25509123
Pubmed	Cruciform Formable Sequences within Pou5f1 Enhancer Are Indispensable for Mouse ES Cell Integrity.	POU5F1 POU5F1B	1.29e-06	2	40	2	33810223
Pubmed	Treatment of sickle cell anemia mouse model with iPS cells generated from autologous skin.	POU5F1 POU5F1B	1.29e-06	2	40	2	18063756
Pubmed	Neural stem cells express Oct-3/4.	POU5F1 POU5F1B	1.29e-06	2	40	2	19664601
Pubmed	Distinct Enhancer Activity of Oct4 in Naive and Primed Mouse Pluripotency.	POU5F1 POU5F1B	1.29e-06	2	40	2	28157483
Pubmed	Isolation of Oct4-expressing extraembryonic endoderm precursor cell lines.	POU5F1 POU5F1B	1.29e-06	2	40	2	19784378
Pubmed	Phosphorylation of Threonine343 Is Crucial for OCT4 Interaction with SOX2 in the Maintenance of Mouse Embryonic Stem Cell Pluripotency.	POU5F1 POU5F1B	1.29e-06	2	40	2	28988986
Pubmed	Abnormal DNA methylation of the Oct-4 enhancer region in cloned mouse embryos.	POU5F1 POU5F1B	1.29e-06	2	40	2	18932201
Pubmed	A POU-domain transcription factor in early stem cells and germ cells of the mammalian embryo.	POU5F1 POU5F1B	1.29e-06	2	40	2	1972777
Pubmed	The oct3 gene, a gene for an embryonic transcription factor, is controlled by a retinoic acid repressible enhancer.	POU5F1 POU5F1B	1.29e-06	2	40	2	1915274
Pubmed	Mouse Oct-3 maps between the tcl12 embryonic lethal gene and the Qa gene in the H-2 complex.	POU5F1 POU5F1B	1.29e-06	2	40	2	1680810
Pubmed	Targeting of de novo DNA methylation throughout the Oct-4 gene regulatory region in differentiating embryonic stem cells.	POU5F1 POU5F1B	1.29e-06	2	40	2	20376339
Pubmed	Organic cation transporter 3 (Oct3) is a distinct catecholamines clearance route in adipocytes mediating the beiging of white adipose tissue.	POU5F1 POU5F1B	1.29e-06	2	40	2	30653498
Pubmed	Heterogeneous DNA methylation status of the regulatory element of the mouse Oct4 gene in adult somatic cell population.	POU5F1 POU5F1B	1.29e-06	2	40	2	15996113
Pubmed	Dual roles of Oct4 in the maintenance of mouse P19 embryonal carcinoma cells: as negative regulator of Wnt/β-catenin signaling and competence provider for Brachyury induction.	POU5F1 POU5F1B	1.29e-06	2	40	2	21083502
Pubmed	Oct4 transcription factor in conjunction with valproic acid accelerates myelin repair in demyelinated optic chiasm in mice.	POU5F1 POU5F1B	1.29e-06	2	40	2	26804242
Pubmed	Conserved, developmentally regulated mechanism couples chromosomal looping and heterochromatin barrier activity at the homeobox gene A locus.	POU5F1 POU5F1B	1.29e-06	2	40	2	21502535
Pubmed	OCT4 Acts as an Integrator of Pluripotency and Signal-Induced Differentiation.	POU5F1 POU5F1B	1.29e-06	2	40	2	27499297
Pubmed	Phenotypic complementation establishes requirements for specific POU domain and generic transactivation function of Oct-3/4 in embryonic stem cells.	POU5F1 POU5F1B	1.29e-06	2	40	2	11839818
Pubmed	Role of Organic Cation Transporter 3 and Plasma Membrane Monoamine Transporter in the Rewarding Properties and Locomotor Sensitizing Effects of Amphetamine in Male andFemale Mice.	POU5F1 POU5F1B	1.29e-06	2	40	2	34948221
Pubmed	A novel Oct4/Pou5f1-like non-coding RNA controls neural maturation and mediates developmental effects of ethanol.	POU5F1 POU5F1B	1.29e-06	2	40	2	33221301
Pubmed	Comparative analysis of human, bovine, and murine Oct-4 upstream promoter sequences.	POU5F1 POU5F1B	1.29e-06	2	40	2	11309664
Pubmed	Developmental fate of embryonic germ cells (EGCs), in vivo and in vitro.	POU5F1 POU5F1B	1.29e-06	2	40	2	12641567
Pubmed	A nontranscriptional role for Oct4 in the regulation of mitotic entry.	POU5F1 POU5F1B	1.29e-06	2	40	2	25324523
Pubmed	A novel subpopulation lacking Oct4 expression in the testicular side population.	POU5F1 POU5F1B	1.29e-06	2	40	2	16328007
Pubmed	Novel variants of Oct-3/4 gene expressed in mouse somatic cells.	POU5F1 POU5F1B	1.29e-06	2	40	2	18765667
Pubmed	Oct4 dependence of chromatin structure within the extended Nanog locus in ES cells.	POU5F1 POU5F1B	1.29e-06	2	40	2	18283123
Pubmed	Transcriptional activation by Oct4 is sufficient for the maintenance and induction of pluripotency.	POU5F1 POU5F1B	1.29e-06	2	40	2	22832160
Pubmed	De-differentiation of mouse interfollicular keratinocytes by the embryonic transcription factor Oct-4.	POU5F1 POU5F1B	1.29e-06	2	40	2	16932739
Pubmed	Mechanisms of OCT4 on 3,5,3'-Tri-iodothyronine and FSH-induced Granulosa Cell Development in Female Mice.	POU5F1 POU5F1B	1.29e-06	2	40	2	34463738
Pubmed	Differential expression of Oct3/4 in human breast cancer and normal tissues.	POU5F1 POU5F1B	1.29e-06	2	40	2	29620155
Pubmed	[The dual role of OCT4].	POU5F1 POU5F1B	1.29e-06	2	40	2	20412747
Pubmed	Glutamine Metabolism Regulates the Pluripotency Transcription Factor OCT4.	POU5F1 POU5F1B	1.29e-06	2	40	2	27346346
Pubmed	The Octamer-Binding Transcription Factor 4 (OCT4) Pseudogene, POU Domain Class 5 Transcription Factor 1B (POU5F1B), is Upregulated in Cervical Cancer and Down-Regulation Inhibits Cell Proliferation and Migration and Induces Apoptosis in Cervical Cancer Cell Lines.	POU5F1 POU5F1B	1.29e-06	2	40	2	30762028
Pubmed	Secondary structure of the oct-3 POU homeodomain as determined by 1H-15N NMR spectroscopy.	POU5F1 POU5F1B	1.29e-06	2	40	2	8097478
Pubmed	Posttranscriptional regulation of maternal Pou5f1/Oct4 during mouse oogenesis and early embryogenesis.	POU5F1 POU5F1B	1.29e-06	2	40	2	32930837
Pubmed	Dissecting Oct3/4-regulated gene networks in embryonic stem cells by expression profiling.	POU5F1 POU5F1B	1.29e-06	2	40	2	17183653
Pubmed	Sox transcription factors require selective interactions with Oct4 and specific transactivation functions to mediate reprogramming.	POU5F1 POU5F1B	1.29e-06	2	40	2	23963638
Pubmed	Critical POU domain residues confer Oct4 uniqueness in somatic cell reprogramming.	POU5F1 POU5F1B	1.29e-06	2	40	2	26877091
Pubmed	The embryonic Octamer factor 3/4 displays distinct DNA binding specificity from those of other Octamer factors.	POU5F1 POU5F1B	1.29e-06	2	40	2	12615074
Pubmed	OCT4 expression mediates partial cardiomyocyte reprogramming of mesenchymal stromal cells.	POU5F1 POU5F1B	1.29e-06	2	40	2	29216265
Pubmed	Effect of ectopic expression of homeoprotein EGAM1C on the cell morphology, growth, and differentiation in a mouse embryonic stem cell line, MG1.19 cells.	POU5F1 POU5F1B	1.29e-06	2	40	2	22367590
Pubmed	Rewirable gene regulatory networks in the preimplantation embryonic development of three mammalian species.	POU5F1 POU5F1B	1.29e-06	2	40	2	20219939
Pubmed	Targeted disruption of organic cation transporter 3 (Oct3) ameliorates ischemic brain damage through modulating histamine and regulatory T cells.	POU5F1 POU5F1B	1.29e-06	2	40	2	22739622
Pubmed	Oct-4: more than just a POUerful marker of the mammalian germline?	POU5F1 POU5F1B	1.29e-06	2	40	2	9524569
Pubmed	Transient pairing of homologous Oct4 alleles accompanies the onset of embryonic stem cell differentiation.	POU5F1 POU5F1B	1.29e-06	2	40	2	25748933
Pubmed	Identification of a nuclear localization signal in OCT4 and generation of a dominant negative mutant by its ablation.	POU5F1 POU5F1B	1.29e-06	2	40	2	15218026
Pubmed	OCT4 and the acquisition of oocyte developmental competence during folliculogenesis.	POU5F1 POU5F1B	1.29e-06	2	40	2	23417407
Pubmed	Expression pattern of Oct-4 in preimplantation embryos of different species.	POU5F1 POU5F1B	1.29e-06	2	40	2	11090438
Pubmed	A saturating mutagenesis CRISPR-Cas9-mediated functional genomic screen identifies cis- and trans-regulatory elements of Oct4 in murine ESCs.	POU5F1 POU5F1B	1.29e-06	2	40	2	32994224
Pubmed	Oct4 regulates the miR-302 cluster in P19 mouse embryonic carcinoma cells.	POU5F1 POU5F1B	1.29e-06	2	40	2	20857206
Pubmed	Dicistronic targeting constructs: reporters and modifiers of mammalian gene expression.	POU5F1 POU5F1B	1.29e-06	2	40	2	8183905
Pubmed	Ectopic POU5F1 in the male germ lineage disrupts differentiation and spermatogenesis in mice.	POU5F1 POU5F1B	1.29e-06	2	40	2	27486267
Pubmed	Evolutionary origin of vertebrate OCT4/POU5 functions in supporting pluripotency.	POU5F1 POU5F1B	1.29e-06	2	40	2	36130934
Pubmed	Networks of Transcription Factors for Oct4 Expression in Mice.	POU5F1 POU5F1B	1.29e-06	2	40	2	28731785
Pubmed	Oct-4 controls cell-cycle progression of embryonic stem cells.	POU5F1 POU5F1B	1.29e-06	2	40	2	19968627
Pubmed	A defined Oct4 level governs cell state transitions of pluripotency entry and differentiation into all embryonic lineages.	POU5F1 POU5F1B	1.29e-06	2	40	2	23629142
Pubmed	Involvement of Oct3/4 in the enhancement of neuronal differentiation of ES cells in neurogenesis-inducing cultures.	POU5F1 POU5F1B	1.29e-06	2	40	2	12702663
Pubmed	Inhibition of Oct 3/4 mitigates the cardiac progenitor-derived myocardial repair in infarcted myocardium.	POU5F1 POU5F1B	1.29e-06	2	40	2	26704423
Pubmed	The Effect of Melatonin on OCT4 Expression and Granulosa Cell Growth in Female Mice.	POU5F1 POU5F1B	1.29e-06	2	40	2	34735714
Pubmed	A unique developmental pattern of Oct-3/4 DNA methylation is controlled by a cis-demodification element.	POU5F1 POU5F1B	1.29e-06	2	40	2	12110668
Pubmed	OCT4 Silencing Triggers Its Epigenetic Repression and Impairs the Osteogenic and Adipogenic Differentiation of Mesenchymal Stromal Cells.	POU5F1 POU5F1B	1.29e-06	2	40	2	31277213
Pubmed	Changes in the Expression of Pluripotency Factor Oct-4 and Intensity of Apoptosis in the Uterus during Spontaneous and Immune-Dependent Abortions in Mice.	POU5F1 POU5F1B	1.29e-06	2	40	2	35501657
Pubmed	CHD4/NuRD maintains demethylation state of rDNA promoters through inhibiting the expression of the rDNA methyltransferase recruiter TIP5.	CHD4 BAZ2A	1.29e-06	2	40	2	23796711
Pubmed	Nucleosome Clutches are Regulated by Chromatin Internal Parameters.	POU5F1 POU5F1B	1.29e-06	2	40	2	33181171
Pubmed	Hierarchical Oct4 Binding in Concert with Primed Epigenetic Rearrangements during Somatic Cell Reprogramming.	POU5F1 POU5F1B	1.29e-06	2	40	2	26832419
Pubmed	The homeodomain of Oct4 is a dimeric binder of methylated CpG elements.	POU5F1 POU5F1B	1.29e-06	2	40	2	36631980
Pubmed	Oct4 was a novel target of Wnt signaling pathway.	POU5F1 POU5F1B	1.29e-06	2	40	2	22120493
Pubmed	Analysis of a transgenic Oct4 enhancer reveals high fidelity long-range chromosomal interactions.	POU5F1 POU5F1B	1.29e-06	2	40	2	26435056
Pubmed	Differential expression of the Oct-4 transcription factor during mouse germ cell differentiation.	POU5F1 POU5F1B	1.29e-06	2	40	2	9507072
Pubmed	Oct-3/4 repression accelerates differentiation of neural progenitor cells in vitro and in vivo.	POU5F1 POU5F1B	1.29e-06	2	40	2	15548425
Pubmed	Genome-wide functional analysis reveals factors needed at the transition steps of induced reprogramming.	POU5F1 POU5F1B	1.29e-06	2	40	2	25043178
Pubmed	OCT4 interprets and enhances nucleosome flexibility.	POU5F1 POU5F1B	1.29e-06	2	40	2	36130732
Pubmed	Computational analysis of single-cell transcriptomics data elucidates the stabilization of Oct4 expression in the E3.25 mouse preimplantation embryo.	POU5F1 POU5F1B	1.29e-06	2	40	2	31222057
Pubmed	The molecular biology of Oct-4 in the early mouse embryo.	POU5F1 POU5F1B	1.29e-06	2	40	2	9835353
Pubmed	Effect of ploidy and parental genome composition on expression of Oct-4 protein in mouse embryos.	POU5F1 POU5F1B	1.29e-06	2	40	2	15183310
Pubmed	OCT4B mediates hypoxia-induced cancer dissemination.	POU5F1 POU5F1B	1.29e-06	2	40	2	30209362
Pubmed	POU5F1 Protein and Gene Expression Analysis in Neonate and Adult Mouse Testicular Germ Cells by Immunohistochemistry and Immunocytochemistry.	POU5F1 POU5F1B	1.29e-06	2	40	2	34788058
Pubmed	A competitive protein interaction network buffers Oct4-mediated differentiation to promote pluripotency in embryonic stem cells.	POU5F1 POU5F1B	1.29e-06	2	40	2	24104477
Pubmed	Sumoylation of Oct4 enhances its stability, DNA binding, and transactivation.	POU5F1 POU5F1B	1.29e-06	2	40	2	17525163
Pubmed	Oct-4 knockdown induces similar patterns of endoderm and trophoblast differentiation markers in human and mouse embryonic stem cells.	POU5F1 POU5F1B	1.29e-06	2	40	2	14990861
Pubmed	Identification of pulmonary Oct-4+ stem/progenitor cells and demonstration of their susceptibility to SARS coronavirus (SARS-CoV) infection in vitro.	POU5F1 POU5F1B	1.29e-06	2	40	2	16772384
Pubmed	Small molecules enable cardiac reprogramming of mouse fibroblasts with a single factor, Oct4.	POU5F1 POU5F1B	1.29e-06	2	40	2	24561253
Pubmed	Auxin-degron system identifies immediate mechanisms of OCT4.	POU5F1 POU5F1B	1.29e-06	2	40	2	34143975
Pubmed	Acidic extracellular pH of tumors induces octamer-binding transcription factor 4 expression in murine fibroblasts in vitro and in vivo.	POU5F1 POU5F1B	1.29e-06	2	40	2	27302093
Pubmed	Characterization of a negative retinoic acid response element in the murine Oct4 promoter.	POU5F1 POU5F1B	1.29e-06	2	40	2	8289793
Pubmed	Force via integrins but not E-cadherin decreases Oct3/4 expression in embryonic stem cells.	POU5F1 POU5F1B	1.29e-06	2	40	2	22037576
Pubmed	Long noncoding RNAs sustain high expression levels of exogenous octamer-binding protein 4 by sponging regulatory microRNAs during cellular reprogramming.	POU5F1 POU5F1B	1.29e-06	2	40	2	31624145
Pubmed	Dynamics and memory of heterochromatin in living cells.	POU5F1 POU5F1B	1.29e-06	2	40	2	22704655
Pubmed	Oct4 redox sensitivity potentiates reprogramming and differentiation.	POU5F1 POU5F1B	1.29e-06	2	40	2	38719541
GeneFamily	POU class homeoboxes and pseudogenes	POU5F1 POU5F1B	5.73e-04	23	28	2	523
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	PLEKHG1 ABR	4.67e-03	66	28	2	722
Coexpression	GSE39556_CD8A_DC_VS_NK_CELL_MOUSE_3H_POST_POLYIC_INJ_DN	RABGAP1 TRIB2 BAZ2A FCGRT LYST	1.27e-05	199	40	5	M9418
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-3m-Mesenchymal-Cilia-bearing_cell\|3m / Sample Type, Dataset, Time_group, and Cell type.	TRPV4 KIF9 SPAG17 C10orf67 LRRC9	9.57e-07	200	40	5	0d14a950172a56b11fdebee8f4e13b0c10e0d592
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-2m-Mesenchymal-Cilia-bearing_cell\|2m / Sample Type, Dataset, Time_group, and Cell type.	TRPV4 KIF9 SPAG17 FCGRT LRRC9	9.57e-07	200	40	5	c6060205cab46628d845edbf17e2c5be7508181c
Drug	AC1MIXXG	BAZ2A POLE WAC	2.02e-05	31	39	3	CID003081982
Drug	aspirin, USP; Down 200; 100uM; HL60; HT_HG-U133A	FAM50B RABGAP1 DENND1C OCRL UBE3B	2.09e-05	197	39	5	1145_DN
Drug	Heliotrine [303-33-3]; Down 200; 12.8uM; PC3; HT_HG-U133A	RABGAP1 FCGRT IL7 UBE3B SNX13	2.09e-05	197	39	5	4277_DN
Drug	AC1N5HQS	NLRP14 FCGRT IL7	2.45e-05	33	39	3	CID004145138
Disease	Congenital Heart Defects	GNA11 POU5F1 AFF4	2.94e-05	44	40	3	C0018798
Disease	colorectal cancer (is_implicated_in)	AURKA CHD4 POLE	5.95e-04	121	40	3	DOID:9256 (is_implicated_in)
Disease	aspartate aminotransferase measurement	DNAJC13 RABGAP1 OCRL BAZ2A FCGRT SNX13	1.28e-03	904	40	6	EFO_0004736

Protein segments in the cluster

Peptide	Gene	Start	Entry
RLKKKMFENEFLLLL	ABR	406	Q12979
KFILALKVLFKAQLE	AURKA	156	O14965
NADFFKQLLELRKIL	ABCD2	81	Q9UBJ2
EKLSKRQLFFRKKLL	BAZ2A	1091	Q9UIF9
KLLLKKKRYQEQLLD	CHMP6	61	Q96FZ7
LQLFKQFIEARLEKL	DENND1C	381	Q8IV53
ESLLYLRLFKLKKEN	AFF4	1006	Q9UHB7
ILRLKFEEKFQKFLE	LRRC9	441	Q6ZRR7
LEQFAKLLKQKRITL	POU5F1B	146	Q06416
NFFLKLKQIKQRERK	RABGAP1	451	Q9Y3P9
LRIKEKLFLEAFKAL	FCGRT	91	P55899
FLQKFKEIRKLSIFQ	PER2	741	O15055
KKLFLQLIAEFKRLG	POLE	1846	Q07864
EFLLILKLKDLKKQY	KIF9	656	Q9HAQ2
KRFLLLFTFLKKNRK	DDX18	411	Q9NVP1
LEQFAKLLKQKRITL	POU5F1	146	Q01860
REKKRILFLYNDLLK	DCST1	586	Q5T197
RLKEFLKNYLTNLLK	CUL1	91	Q13616
LFLNKKDLLEDKILY	GNA11	271	P29992
LNFQVELLLDKLKQK	ITGAV	521	P06756
LLSSKKFLENLLEKF	DNAJC13	501	O75165
DRLILFLNKLILNKK	DNAJC13	911	O75165
FLKQEIKRFDKLLFV	DNAH14	3196	Q0VDD8
EQKKLNDLCFLKRLL	IL7	146	P13232
FLKIIRQKEKNVFLL	LYST	1296	Q99698
EIKNKFLARRFKLLE	CHD4	1776	Q14839
FLIKKKANLNALDRF	POTEA	216	Q6S8J7
EKRKKDLNAYLQLLL	SNX13	651	Q9Y5W8
LDKKQIRAIFLFEFK	SETMAR	346	Q53H47
ILFLRQQIKELEKLK	WAC	626	Q9BTA9
KSLINKKDLQRLLKF	OCRL	436	Q01968
KKDLQRLLKFDQLNI	OCRL	441	Q01968
GKLLKFQLLQIKFKD	SPAG17	126	Q6Q759
FLLSLVDLNKNFKKI	SEMA3D	91	O95025
FLKQLLQLKFEDRLK	C10orf67	121	Q8IYJ2
LVLRDLKLRKFIFKD	TRIB2	171	Q92519
IFKIARKLLFLFRIK	UBE3B	76	Q7Z3V4
KNERTLFLFDKLLLI	PLEKHG1	336	Q9ULL1
LFLFDKLLLITKKRD	PLEKHG1	341	Q9ULL1
LLIFFLKRRNKKKQQ	PTPRH	771	Q9HD43
IQKILFKDLFRFLLV	TRPV4	606	Q9HBA0
QFLKKALQGLRKDFL	FAM50B	211	Q9Y247
ELNKEELNTFKLFLK	NLRP14	21	Q86W24