Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DNAH3 DYNC2H1 DNAH17 DNAH11

8.40e-06181494GO:0008569
GeneOntologyMolecularFunctionprotein serine kinase activity

TNIK ROCK2 CDC42BPA SGK1 CIT MAP3K4 SGK3 MYO3A PRKCG STK39 ATM DYRK3

1.85e-0536314912GO:0106310
GeneOntologyMolecularFunctiondynein light intermediate chain binding

DNAH3 DYNC2H1 DNAH17 DNAH11

5.30e-05281494GO:0051959
GeneOntologyMolecularFunctionprotein serine/threonine kinase activity

TNIK ROCK2 CDC42BPA SGK1 CIT MAP3K4 SGK3 MYO3A PRKCG STK39 ATM DYRK3

1.34e-0444614912GO:0004674
GeneOntologyMolecularFunctiondynein intermediate chain binding

DNAH3 DYNC2H1 DNAH17 DNAH11

1.62e-04371494GO:0045505
GeneOntologyMolecularFunctionprotein kinase activity

TNIK ROCK2 CDC42BPA SGK1 CIT MAP3K4 SGK3 MYO3A FER FES PRKCG STK39 ATM DYRK3

1.65e-0460014914GO:0004672
GeneOntologyMolecularFunctionNACHT domain binding

TRIM16 TRIM16L

1.65e-0431492GO:0032089
GeneOntologyMolecularFunctionprotein phosphatase activator activity

PPP2R5C PPP2R5D PPP2R5E

2.56e-04171493GO:0072542
GeneOntologyMolecularFunctioncytoskeletal motor activity

DNAH3 MYH6 DYNC2H1 MYO3A DNAH17 DNAH11

2.59e-041181496GO:0003774
GeneOntologyMolecularFunctionryanodine-sensitive calcium-release channel activity

RYR2 RYR3

3.29e-0441492GO:0005219
GeneOntologyMolecularFunctioncalmodulin binding

MYH6 IQGAP2 RYR2 RYR3 MYO3A ASPM CDK5RAP2 PLCB3

3.39e-042301498GO:0005516
GeneOntologyMolecularFunctionphosphatase activator activity

PPP2R5C PPP2R5D PPP2R5E

4.23e-04201493GO:0019211
GeneOntologyMolecularFunctioncytoskeleton-nuclear membrane anchor activity

SYNE1 SYNE2

5.45e-0451492GO:0140444
GeneOntologyMolecularFunctiontransferase activity, transferring phosphorus-containing groups

TNIK ROCK2 TUT4 CDC42BPA SGK1 POLR3H CIT MAP3K4 SGK3 PARP1 MYO3A FER FES PRKCG STK39 ATM DYRK3

6.44e-0493814917GO:0016772
GeneOntologyMolecularFunctioncalcium-induced calcium release activity

RYR2 RYR3

8.13e-0461492GO:0048763
GeneOntologyMolecularFunctionphosphotransferase activity, alcohol group as acceptor

TNIK ROCK2 CDC42BPA SGK1 CIT MAP3K4 SGK3 MYO3A FER FES PRKCG STK39 ATM DYRK3

8.73e-0470914914GO:0016773
GeneOntologyMolecularFunctionenzyme activator activity

DOCK1 ROCK2 CAB39 GAPVD1 IQGAP2 TBC1D2B RICTOR ALS2 PPP2R5C PPP2R5D PPP2R5E ARHGAP20 ACAP3

1.29e-0365614913GO:0008047
GeneOntologyMolecularFunctioncytoskeletal protein binding

ROCK2 MYH6 CLASP1 IQGAP2 SGK1 SYNE1 BCCIP TOGARAM1 INO80 MYO3A FBXO25 SYNE2 CEP70 FES CDK5RAP2 MACF1 FERMT2 UTRN

1.42e-03109914918GO:0008092
GeneOntologyMolecularFunctionkinase activity

TNIK ROCK2 CDC42BPA SGK1 CIT MAP3K4 SGK3 MYO3A FER FES PRKCG STK39 ATM DYRK3

1.77e-0376414914GO:0016301
GeneOntologyMolecularFunctionmicrotubule motor activity

DNAH3 DYNC2H1 DNAH17 DNAH11

1.86e-03701494GO:0003777
GeneOntologyBiologicalProcessmicrotubule bundle formation

CLASP1 TOGARAM1 DNAAF11 CFAP43 ARMC2 FSIP2 DNAH17 FES CFAP58 CC2D2A CDK5RAP2 CFAP57 HYDIN CCDC40

3.01e-1214515014GO:0001578
GeneOntologyBiologicalProcessmicrotubule cytoskeleton organization

ROCK2 CDC42BPA CLASP1 SGK1 IFT172 BCCIP TOGARAM1 DNAAF11 CFAP43 INO80 ARMC2 FSIP2 GCC2 DNAH17 SYNE2 CEP70 ASPM FER FES CFAP58 CC2D2A CDK5RAP2 CFAP57 HYDIN CCDC40

7.92e-1172015025GO:0000226
GeneOntologyBiologicalProcessmicrotubule-based process

ROCK2 DNAH3 CDC42BPA CLASP1 DYNC2H1 SGK1 IFT172 BCCIP TOGARAM1 APOB DNAAF11 CFAP43 INO80 ARMC2 FSIP2 GCC2 DNAH17 SYNE2 CEP70 ASPM FER FES CFAP58 CC2D2A CDK5RAP2 MACF1 CFAP57 HYDIN CCDC40 DNAH11

1.15e-10105815030GO:0007017
GeneOntologyBiologicalProcessaxoneme assembly

TOGARAM1 DNAAF11 CFAP43 ARMC2 FSIP2 DNAH17 CFAP58 CC2D2A CFAP57 HYDIN CCDC40

4.33e-1010915011GO:0035082
GeneOntologyBiologicalProcesscilium organization

DYNC2H1 IFT172 SYNE1 TBC1D2B TOGARAM1 DNAAF11 CFAP43 ARMC2 FSIP2 DNAH17 SYNE2 CEP70 CFAP58 CC2D2A TTC17 CFAP57 HYDIN CCDC40

1.21e-0847615018GO:0044782
GeneOntologyBiologicalProcessorganelle assembly

MYH6 CLASP1 DYNC2H1 ZPBP IFT172 SYNE1 TBC1D2B BCCIP TOGARAM1 RPS23 DNAAF11 CFAP43 INO80 ARMC2 VPS37B FSIP2 NRXN2 DNAH17 SYNE2 CEP70 ASPM CFAP58 CC2D2A CDK5RAP2 ATM CFAP57 HYDIN CCDC40

1.21e-08113815028GO:0070925
GeneOntologyBiologicalProcesscilium assembly

DYNC2H1 IFT172 SYNE1 TBC1D2B TOGARAM1 DNAAF11 CFAP43 ARMC2 FSIP2 DNAH17 SYNE2 CEP70 CFAP58 CC2D2A CFAP57 HYDIN CCDC40

2.64e-0844415017GO:0060271
GeneOntologyBiologicalProcesscilium movement involved in cell motility

DNAH3 DYNC2H1 APOB DNAAF11 CFAP43 ARMC2 FSIP2 DNAH17 CFAP58 CFAP57 CCDC40 DNAH11

4.56e-0821015012GO:0060294
GeneOntologyBiologicalProcesscilium-dependent cell motility

DNAH3 DYNC2H1 APOB DNAAF11 CFAP43 ARMC2 FSIP2 DNAH17 CFAP58 CFAP57 CCDC40 DNAH11

5.91e-0821515012GO:0060285
GeneOntologyBiologicalProcesscilium or flagellum-dependent cell motility

DNAH3 DYNC2H1 APOB DNAAF11 CFAP43 ARMC2 FSIP2 DNAH17 CFAP58 CFAP57 CCDC40 DNAH11

5.91e-0821515012GO:0001539
GeneOntologyBiologicalProcesscilium movement

DNAH3 DYNC2H1 APOB DNAAF11 CFAP43 ARMC2 FSIP2 DNAH17 CFAP58 CFAP57 HYDIN CCDC40 DNAH11

6.22e-0826115013GO:0003341
GeneOntologyBiologicalProcessplasma membrane bounded cell projection assembly

TNIK DYNC2H1 IFT172 SYNE1 TBC1D2B TOGARAM1 DNAAF11 CFAP43 ARMC2 FSIP2 MYO3A DNAH17 SYNE2 CEP70 FER CFAP58 CC2D2A CFAP57 HYDIN CCDC40

9.01e-0867015020GO:0120031
GeneOntologyBiologicalProcesscell projection assembly

TNIK DYNC2H1 IFT172 SYNE1 TBC1D2B TOGARAM1 DNAAF11 CFAP43 ARMC2 FSIP2 MYO3A DNAH17 SYNE2 CEP70 FER CFAP58 CC2D2A CFAP57 HYDIN CCDC40

1.29e-0768515020GO:0030031
GeneOntologyBiologicalProcessmotile cilium assembly

DNAAF11 CFAP43 ARMC2 FSIP2 CFAP58 CC2D2A CFAP57 CCDC40

2.55e-07881508GO:0044458
GeneOntologyBiologicalProcessregulation of organelle organization

ROCK2 CLASP1 IQGAP2 SGK1 VPS13C SYNE1 TBC1D2B TOGARAM1 RICTOR INO80 CIT MAP3K4 PARP1 MYO3A SCARB2 SYNE2 NCAPD2 CEP70 FER FBXO7 FES CDK5RAP2 ATM FERMT2 PCID2 SMG6 RAD21

1.28e-06134215027GO:0033043
GeneOntologyBiologicalProcessprotein localization to cilium

DYNC2H1 DNAAF11 FSIP2 CFAP58 CC2D2A CCDC40 DNAH11

1.47e-06771507GO:0061512
GeneOntologyBiologicalProcesssperm motility

APOB DNAAF11 CFAP43 ARMC2 FSIP2 PDILT CFAP58 CFAP57 CCDC40 DNAH11

1.53e-0619315010GO:0097722
GeneOntologyBiologicalProcessmicrotubule-based movement

DNAH3 DYNC2H1 IFT172 APOB DNAAF11 CFAP43 ARMC2 FSIP2 DNAH17 SYNE2 CFAP58 CFAP57 HYDIN CCDC40 DNAH11

3.25e-0649315015GO:0007018
GeneOntologyBiologicalProcessflagellated sperm motility

APOB DNAAF11 CFAP43 ARMC2 FSIP2 CFAP58 CFAP57 CCDC40 DNAH11

9.05e-061861509GO:0030317
GeneOntologyBiologicalProcessregulation of microtubule-based process

ROCK2 CLASP1 SGK1 TOGARAM1 CFAP43 CEP70 FES CDK5RAP2 MACF1 CCDC40 DNAH11

1.02e-0529315011GO:0032886
GeneOntologyBiologicalProcessnuclear chromosome segregation

CLASP1 RAD21L1 BCCIP SYCP3 INO80 CIT NCAPD2 ASPM CDK5RAP2 ATM PCID2 RAD21

1.19e-0535615012GO:0098813
GeneOntologyBiologicalProcessprotein localization to motile cilium

DNAAF11 CFAP58 DNAH11

2.06e-0581503GO:0120229
GeneOntologyBiologicalProcessreplication-born double-strand break repair via sister chromatid exchange

RAD21L1 FANCB RAD21

2.06e-0581503GO:1990414
GeneOntologyBiologicalProcesspeptidyl-threonine phosphorylation

ROCK2 CAB39 CDC42BPA MYO3A PPP2R5D STK39 DYRK3

2.13e-051151507GO:0018107
GeneOntologyBiologicalProcessnuclear division

CLASP1 TRIM75 RAD21L1 BCCIP SYCP3 INO80 CIT BANF1 NCAPD2 ASPM CDK5RAP2 ATM PCID2 RAD21

2.32e-0551215014GO:0000280
GeneOntologyBiologicalProcessmitotic sister chromatid segregation

CLASP1 BCCIP INO80 CIT NCAPD2 CDK5RAP2 ATM PCID2 RAD21

2.56e-052121509GO:0000070
GeneOntologyBiologicalProcessregulation of chromosome organization

INO80 CIT MAP3K4 PARP1 NCAPD2 CDK5RAP2 ATM PCID2 SMG6 RAD21

2.58e-0526615010GO:0033044
GeneOntologyBiologicalProcessgamete generation

HEXB TUT4 TRIM75 ZPBP SYNE1 RAD21L1 SYCP3 APOB CFAP43 ARMC2 CIT ADAM28 USP26 FSIP2 PDILT ASPM FER CFAP58 ATM CFAP57

3.02e-0598215020GO:0007276
GeneOntologyBiologicalProcesspeptidyl-threonine modification

ROCK2 CAB39 CDC42BPA MYO3A PPP2R5D STK39 DYRK3

3.64e-051251507GO:0018210
GeneOntologyBiologicalProcesschromosome organization

CLASP1 RAD21L1 BCCIP SYCP3 INO80 EZH1 CIT BANF1 MAP3K4 PARP1 NCAPD2 CDK5RAP2 ATM PCID2 SMG6 RAD21

4.12e-0568615016GO:0051276
GeneOntologyBiologicalProcesschromosome separation

SYCP3 NCAPD2 CDK5RAP2 ATM PCID2 RAD21

4.44e-05881506GO:0051304
GeneOntologyBiologicalProcessgerm cell development

HEXB TUT4 ZPBP SYCP3 CFAP43 ARMC2 FSIP2 PDILT ASPM FER CFAP58 ATM CFAP57

5.27e-0548215013GO:0007281
GeneOntologyBiologicalProcessmulticellular organismal reproductive process

HEXB TUT4 TRIM75 ZPBP SYNE1 RAD21L1 SYCP3 APOB CFAP43 ARMC2 CIT ADAM28 USP26 FSIP2 PARP1 PDILT ASPM FER CFAP58 ATM CFAP57 LARGE1

5.31e-05119415022GO:0048609
GeneOntologyBiologicalProcesssperm flagellum assembly

CFAP43 ARMC2 FSIP2 CFAP58 CFAP57

5.39e-05561505GO:0120316
GeneOntologyBiologicalProcessorganelle fission

CLASP1 TRIM75 RAD21L1 BCCIP SYCP3 INO80 CIT BANF1 NCAPD2 ASPM CDK5RAP2 ATM PCID2 RAD21

7.53e-0557115014GO:0048285
GeneOntologyBiologicalProcesspositive regulation of organelle organization

ROCK2 CLASP1 TOGARAM1 RICTOR INO80 MAP3K4 NCAPD2 FER FBXO7 FES CDK5RAP2 ATM FERMT2 RAD21

7.96e-0557415014GO:0010638
GeneOntologyBiologicalProcesspeptidyl-serine phosphorylation

ROCK2 CAB39 SGK1 RICTOR SGK3 MYO3A PRKCG STK39 ATM DYRK3

8.60e-0530715010GO:0018105
GeneOntologyBiologicalProcessdevelopmental process involved in reproduction

HEXB TUT4 ZPBP SYNE1 RAD21L1 SYCP3 APOB DNAAF11 CFAP43 ARMC2 CIT ADAM28 MAP3K4 USP26 FSIP2 PARP1 PDILT ASPM FER CFAP58 ATM CFAP57

8.72e-05123515022GO:0003006
GeneOntologyBiologicalProcesspositive regulation of supramolecular fiber organization

ROCK2 CLASP1 TOGARAM1 RICTOR FER FES CDK5RAP2 FERMT2

9.59e-051961508GO:1902905
GeneOntologyBiologicalProcesspositive regulation of protein polymerization

CLASP1 TOGARAM1 RICTOR FER FES CDK5RAP2

1.01e-041021506GO:0032273
GeneOntologyBiologicalProcesssister chromatid segregation

CLASP1 BCCIP INO80 CIT NCAPD2 CDK5RAP2 ATM PCID2 RAD21

1.04e-042541509GO:0000819
GeneOntologyBiologicalProcesssperm axoneme assembly

CFAP43 ARMC2 FSIP2 CFAP58

1.05e-04341504GO:0007288
GeneOntologyBiologicalProcessmitotic nuclear division

CLASP1 BCCIP INO80 CIT BANF1 NCAPD2 CDK5RAP2 ATM PCID2 RAD21

1.09e-0431615010GO:0140014
GeneOntologyBiologicalProcesspeptidyl-serine modification

ROCK2 CAB39 SGK1 RICTOR SGK3 MYO3A PRKCG STK39 ATM DYRK3

1.18e-0431915010GO:0018209
GeneOntologyBiologicalProcesscentrosome localization

SYNE1 CCDC141 SYNE2 ASPM

1.18e-04351504GO:0051642
GeneOntologyBiologicalProcessprotein localization to organelle

TNIK ROCK2 DYNC2H1 VPS13C SYNE1 DNAAF11 VPS37B RYR2 FSIP2 PARP1 GCC2 SCARB2 FBXO7 CFAP58 CC2D2A MACF1 FERMT2 CCDC40 DNAH11 RAD21

1.29e-04109115020GO:0033365
GeneOntologyBiologicalProcesscellular process involved in reproduction in multicellular organism

HEXB TUT4 ZPBP SYCP3 CFAP43 ARMC2 FSIP2 PDILT ASPM FER CFAP58 ATM CFAP57

1.29e-0452715013GO:0022412
GeneOntologyBiologicalProcesspositive regulation of cytoskeleton organization

ROCK2 CLASP1 TOGARAM1 RICTOR FER FES CDK5RAP2 FERMT2

1.31e-042051508GO:0051495
GeneOntologyBiologicalProcessmicrotubule organizing center localization

SYNE1 CCDC141 SYNE2 ASPM

1.32e-04361504GO:0061842
GeneOntologyBiologicalProcessnegative regulation of chromosome organization

PARP1 CDK5RAP2 ATM PCID2 SMG6 RAD21

1.32e-041071506GO:2001251
GeneOntologyBiologicalProcessmale gamete generation

ZPBP SYNE1 RAD21L1 SYCP3 APOB CFAP43 ARMC2 CIT ADAM28 USP26 FSIP2 PDILT ASPM CFAP58 ATM CFAP57

1.41e-0476215016GO:0048232
GeneOntologyBiologicalProcessregulation of microtubule polymerization

CLASP1 SGK1 TOGARAM1 FES CDK5RAP2

1.47e-04691505GO:0031113
GeneOntologyBiologicalProcesspositive regulation of microtubule polymerization

CLASP1 TOGARAM1 FES CDK5RAP2

1.47e-04371504GO:0031116
GeneOntologyBiologicalProcesschromosome segregation

CLASP1 RAD21L1 BCCIP SYCP3 INO80 CIT NCAPD2 ASPM CDK5RAP2 ATM PCID2 RAD21

1.56e-0446515012GO:0007059
GeneOntologyBiologicalProcessepithelial cilium movement involved in determination of left/right asymmetry

DNAAF11 CCDC40 DNAH11

1.61e-04151503GO:0060287
GeneOntologyBiologicalProcesssexual reproduction

HEXB TUT4 TRIM75 ZPBP SYNE1 RAD21L1 SYCP3 APOB CFAP43 ARMC2 CIT ADAM28 USP26 FSIP2 PDILT NCAPD2 ASPM FER CFAP58 ATM CFAP57 RAD21

2.07e-04131215022GO:0019953
GeneOntologyBiologicalProcessdetermination of bilateral symmetry

DYNC2H1 IFT172 DNAAF11 MAP3K4 CC2D2A CCDC40 DNAH11

2.08e-041651507GO:0009855
GeneOntologyBiologicalProcessspecification of symmetry

DYNC2H1 IFT172 DNAAF11 MAP3K4 CC2D2A CCDC40 DNAH11

2.08e-041651507GO:0009799
GeneOntologyBiologicalProcessaxonemal dynein complex assembly

DNAAF11 DNAH17 CFAP57 CCDC40

2.21e-04411504GO:0070286
GeneOntologyBiologicalProcesspositive regulation of microtubule polymerization or depolymerization

CLASP1 TOGARAM1 FES CDK5RAP2

2.43e-04421504GO:0031112
GeneOntologyBiologicalProcesspositive regulation of protein-containing complex assembly

CLASP1 TOGARAM1 RICTOR FER FES CDK5RAP2 ATM FERMT2

2.62e-042271508GO:0031334
GeneOntologyBiologicalProcessregulation of chromosome separation

NCAPD2 CDK5RAP2 ATM PCID2 RAD21

2.78e-04791505GO:1905818
GeneOntologyBiologicalProcessregulation of cilium beat frequency

CFAP43 CCDC40 DNAH11

2.84e-04181503GO:0003356
GeneOntologyBiologicalProcessregulation of cytoskeleton organization

ROCK2 CLASP1 IQGAP2 SGK1 TOGARAM1 RICTOR CIT MYO3A CEP70 FER FES CDK5RAP2 FERMT2

3.22e-0457915013GO:0051493
GeneOntologyBiologicalProcessspermatogenesis

ZPBP SYNE1 RAD21L1 SYCP3 APOB CFAP43 ARMC2 CIT ADAM28 USP26 FSIP2 PDILT ASPM CFAP58 CFAP57

3.52e-0474415015GO:0007283
GeneOntologyBiologicalProcesspositive regulation of cellular component organization

TNIK ROCK2 CLASP1 SGK1 SYNE1 TOGARAM1 RICTOR INO80 MAP3K4 MYO3A PPP2R5D AP2B1 SCARB2 NCAPD2 FER FBXO7 FES CDK5RAP2 MACF1 ATM FERMT2 RAD21

3.63e-04136615022GO:0051130
GeneOntologyBiologicalProcessresponse to aldosterone

SGK1 PARP1 STK39

3.92e-04201503GO:1904044
GeneOntologyBiologicalProcessprotein targeting to vacuole

VPS13C VPS37B GCC2 SCARB2

4.41e-04491504GO:0006623
GeneOntologyBiologicalProcessprotein localization to vacuole

ROCK2 VPS13C VPS37B GCC2 SCARB2

4.83e-04891505GO:0072665
GeneOntologyBiologicalProcessmitotic cell cycle process

ROCK2 CLASP1 IQGAP2 BCCIP INO80 CIT BANF1 CUL5 USP26 PPP2R5C NCAPD2 FBXO7 CDK5RAP2 ATM PCID2 RAD21

5.00e-0485415016GO:1903047
GeneOntologyBiologicalProcessnegative regulation of hippo signaling

WWC3 CIT WWC1

5.25e-04221503GO:0035331
GeneOntologyBiologicalProcessregulation of chromosome segregation

CIT NCAPD2 CDK5RAP2 ATM PCID2 RAD21

5.43e-041391506GO:0051983
GeneOntologyBiologicalProcessregulation of cell-matrix adhesion

ROCK2 CLASP1 POSTN MACF1 FERMT2 UTRN

5.86e-041411506GO:0001952
GeneOntologyBiologicalProcessnegative regulation of mitotic metaphase/anaphase transition

CDK5RAP2 ATM PCID2 RAD21

5.97e-04531504GO:0045841
GeneOntologyBiologicalProcessnegative regulation of mitotic sister chromatid segregation

CDK5RAP2 ATM PCID2 RAD21

5.97e-04531504GO:0033048
GeneOntologyBiologicalProcessnegative regulation of sister chromatid segregation

CDK5RAP2 ATM PCID2 RAD21

5.97e-04531504GO:0033046
GeneOntologyBiologicalProcessnegative regulation of mitotic sister chromatid separation

CDK5RAP2 ATM PCID2 RAD21

5.97e-04531504GO:2000816
GeneOntologyBiologicalProcessmaintenance of location in cell

HEXB HSP90B1 VPS13C SYNE1 RYR2 RYR3 ASPM PLCB3

6.30e-042591508GO:0051651
GeneOntologyBiologicalProcessmaintenance of location

HEXB HSP90B1 VPS13C SYNE1 APOB RYR2 RYR3 ASPM ANGPTL3 PLCB3

6.56e-0439615010GO:0051235
GeneOntologyBiologicalProcessspermatid development

ZPBP SYCP3 CFAP43 ARMC2 FSIP2 PDILT CFAP58 CFAP57

6.79e-042621508GO:0007286
GeneOntologyBiologicalProcessglycosphingolipid catabolic process

HEXB GLB1 SCARB2

6.82e-04241503GO:0046479
GeneOntologyBiologicalProcessnegative regulation of metaphase/anaphase transition of cell cycle

CDK5RAP2 ATM PCID2 RAD21

6.87e-04551504GO:1902100
GeneOntologyBiologicalProcessnegative regulation of chromosome separation

CDK5RAP2 ATM PCID2 RAD21

6.87e-04551504GO:1905819
GeneOntologyBiologicalProcesscell cycle process

ROCK2 CLASP1 IQGAP2 TRIM75 RAD21L1 BCCIP SYCP3 INO80 CIT BANF1 CUL5 USP26 PPP2R5C NCAPD2 ASPM FBXO7 FES CDK5RAP2 ATM PCID2 DYRK3 RAD21

7.45e-04144115022GO:0022402
GeneOntologyBiologicalProcessmicrotubule anchoring

CLASP1 BCCIP GCC2

7.71e-04251503GO:0034453
GeneOntologyBiologicalProcessnegative regulation of chromosome segregation

CDK5RAP2 ATM PCID2 RAD21

7.87e-04571504GO:0051985
GeneOntologyBiologicalProcessmetaphase/anaphase transition of mitotic cell cycle

CIT CDK5RAP2 ATM PCID2 RAD21

8.22e-041001505GO:0007091
GeneOntologyBiologicalProcessspermatid differentiation

ZPBP SYCP3 CFAP43 ARMC2 FSIP2 PDILT CFAP58 CFAP57

8.66e-042721508GO:0048515
GeneOntologyBiologicalProcessepithelial cilium movement involved in extracellular fluid movement

DNAAF11 CFAP43 CCDC40 DNAH11

8.96e-04591504GO:0003351
GeneOntologyBiologicalProcessdetermination of left/right symmetry

DYNC2H1 IFT172 DNAAF11 CC2D2A CCDC40 DNAH11

9.29e-041541506GO:0007368
GeneOntologyBiologicalProcessmetaphase/anaphase transition of cell cycle

CIT CDK5RAP2 ATM PCID2 RAD21

9.40e-041031505GO:0044784
GeneOntologyBiologicalProcessregulation of mitotic sister chromatid segregation

CDK5RAP2 ATM PCID2 RAD21

9.55e-04601504GO:0033047
GeneOntologyBiologicalProcessregulation of telomere capping

MAP3K4 ATM SMG6

9.70e-04271503GO:1904353
GeneOntologyBiologicalProcessglycolipid catabolic process

HEXB GLB1 SCARB2

9.70e-04271503GO:0019377
GeneOntologyBiologicalProcessactin filament-based process

TNIK ROCK2 HSP90B1 MYH6 CDC42BPA CLASP1 IQGAP2 RICTOR CIT RYR2 ADORA1 MYO3A SYNE2 FER TTC17 FERMT2

1.01e-0391215016GO:0030029
GeneOntologyBiologicalProcessextracellular transport

DNAAF11 CFAP43 CCDC40 DNAH11

1.08e-03621504GO:0006858
GeneOntologyBiologicalProcessmitotic cell cycle

ROCK2 CLASP1 IQGAP2 BCCIP SYCP3 INO80 CIT BANF1 CUL5 USP26 PPP2R5C NCAPD2 FBXO7 CDK5RAP2 ATM PCID2 RAD21

1.15e-03101415017GO:0000278
GeneOntologyBiologicalProcessregulation of microtubule polymerization or depolymerization

CLASP1 SGK1 TOGARAM1 FES CDK5RAP2

1.16e-031081505GO:0031110
GeneOntologyBiologicalProcessleft/right pattern formation

DYNC2H1 IFT172 DNAAF11 CC2D2A CCDC40 DNAH11

1.21e-031621506GO:0060972
GeneOntologyBiologicalProcessnegative regulation of mitotic nuclear division

CDK5RAP2 ATM PCID2 RAD21

1.22e-03641504GO:0045839
GeneOntologyCellularComponent9+2 motile cilium

DNAH3 DYNC2H1 IFT172 CFAP43 USP26 FSIP2 DNAH17 CFAP58 CFAP57 DNAH11

9.90e-0623815210GO:0097729
GeneOntologyCellularComponentmotile cilium

DNAH3 DYNC2H1 IFT172 DNAAF11 CFAP43 USP26 FSIP2 DNAH17 CFAP58 CFAP57 CCDC40 DNAH11

1.16e-0535515212GO:0031514
GeneOntologyCellularComponentsmooth endoplasmic reticulum

HSP90B1 APOB RYR2 RYR3 DNAJC3

2.05e-05461525GO:0005790
GeneOntologyCellularComponentaxoneme

DNAH3 DYNC2H1 IFT172 TOGARAM1 CFAP43 DNAH17 HYDIN CCDC40 DNAH11

2.13e-052071529GO:0005930
GeneOntologyCellularComponentciliary plasm

DNAH3 DYNC2H1 IFT172 TOGARAM1 CFAP43 DNAH17 HYDIN CCDC40 DNAH11

2.21e-052081529GO:0097014
GeneOntologyCellularComponentsupramolecular fiber

CAB39 KRT4 DNAH3 MYH6 CLASP1 IQGAP2 DYNC2H1 SYNE1 TOGARAM1 INO80 PPL RYR2 RYR3 MYO3A SPHKAP DNAH17 SYNE2 ASPM CDK5RAP2 MACF1 FERMT2 DNAH11

4.43e-05117915222GO:0099512
GeneOntologyCellularComponentsupramolecular polymer

CAB39 KRT4 DNAH3 MYH6 CLASP1 IQGAP2 DYNC2H1 SYNE1 TOGARAM1 INO80 PPL RYR2 RYR3 MYO3A SPHKAP DNAH17 SYNE2 ASPM CDK5RAP2 MACF1 FERMT2 DNAH11

4.90e-05118715222GO:0099081
GeneOntologyCellularComponentI band

CAB39 MYH6 RYR2 RYR3 SPHKAP SYNE2 FERMT2

2.16e-041661527GO:0031674
GeneOntologyCellularComponentchromosomal region

THOC1 CLASP1 SYCP3 EZH1 THOC2 PARP1 PPP2R5C NCAPD2 ATM SMG6 RAD21

2.65e-0442115211GO:0098687
GeneOntologyCellularComponentprotein phosphatase type 2A complex

PPP2R5C PPP2R5D PPP2R5E

2.84e-04181523GO:0000159
GeneOntologyCellularComponentcytoplasmic region

DNAH3 CLASP1 DYNC2H1 IFT172 TOGARAM1 CFAP43 DNAH17 HYDIN CCDC40 DNAH11

3.12e-0436015210GO:0099568
GeneOntologyCellularComponentmicrotubule organizing center

ROCK2 FAM184A CLASP1 IFT172 POLR3H BCCIP TOGARAM1 ALS2 ECPAS CCDC141 CCDC112 CEP70 ASPM CFAP58 CDK5RAP2 ATM DYRK3

3.85e-0491915217GO:0005815
GeneOntologyCellularComponentsarcomere

CAB39 MYH6 SYNE1 RYR2 RYR3 SPHKAP SYNE2 FERMT2

4.86e-042491528GO:0030017
GeneOntologyCellularComponentcentrosome

ROCK2 FAM184A CLASP1 POLR3H BCCIP ALS2 ECPAS CCDC141 CCDC112 CEP70 ASPM CFAP58 CDK5RAP2 ATM DYRK3

5.06e-0477015215GO:0005813
GeneOntologyCellularComponentplasma membrane bounded cell projection cytoplasm

DNAH3 DYNC2H1 IFT172 TOGARAM1 CFAP43 DNAH17 HYDIN CCDC40 DNAH11

5.34e-043171529GO:0032838
GeneOntologyCellularComponentdynein complex

DNAH3 DYNC2H1 DNAH17 DNAH11

6.41e-04541524GO:0030286
GeneOntologyCellularComponentTHO complex

THOC1 THOC2

7.73e-0461522GO:0000347
GeneOntologyCellularComponentTHO complex part of transcription export complex

THOC1 THOC2

7.73e-0461522GO:0000445
GeneOntologyCellularComponentZ disc

CAB39 MYH6 RYR2 RYR3 SPHKAP SYNE2

8.39e-041511526GO:0030018
GeneOntologyCellularComponentmyofibril

CAB39 MYH6 SYNE1 RYR2 RYR3 SPHKAP SYNE2 FERMT2

8.87e-042731528GO:0030016
GeneOntologyCellularComponentmeiotic cohesin complex

RAD21L1 RAD21

1.08e-0371522GO:0030893
GeneOntologyCellularComponentcell leading edge

CDC42BPA IQGAP2 ALS2 CIT ADORA1 SYNE2 ANGPTL3 FER MACF1 FERMT2 WWC1

1.10e-0350015211GO:0031252
GeneOntologyCellularComponentcontractile muscle fiber

CAB39 MYH6 SYNE1 RYR2 RYR3 SPHKAP SYNE2 FERMT2

1.30e-032901528GO:0043292
GeneOntologyCellularComponentlamellipodium

CDC42BPA IQGAP2 ALS2 SYNE2 ANGPTL3 FER FERMT2

1.50e-032301527GO:0030027
GeneOntologyCellularComponentmicrotubule

DNAH3 CLASP1 IQGAP2 DYNC2H1 TOGARAM1 INO80 DNAH17 ASPM CDK5RAP2 MACF1 DNAH11

1.83e-0353315211GO:0005874
GeneOntologyCellularComponentchromosome, telomeric region

THOC1 EZH1 THOC2 PARP1 ATM SMG6

1.84e-031761526GO:0000781
GeneOntologyCellularComponentvacuolar lumen

HEXB APOB GLB1 SCARB2 PADI2 DNAJC3

1.95e-031781526GO:0005775
GeneOntologyCellularComponentcilium

DNAH3 DYNC2H1 IFT172 TOGARAM1 DNAAF11 CFAP43 USP26 FSIP2 DNAH17 CFAP58 CC2D2A CFAP57 HYDIN CCDC40 DNAH11

2.34e-0389815215GO:0005929
GeneOntologyCellularComponentcytoplasmic side of plasma membrane

RYR2 RYR3 AP2B1 FER FES FERMT2

2.36e-031851526GO:0009898
GeneOntologyCellularComponentmicrotubule end

CLASP1 ASPM CDK5RAP2

2.64e-03381523GO:1990752
GeneOntologyCellularComponentnuclear membrane protein complex

SYNE1 SYNE2

2.77e-03111522GO:0106083
GeneOntologyCellularComponentnuclear membrane microtubule tethering complex

SYNE1 SYNE2

2.77e-03111522GO:0106094
GeneOntologyCellularComponentmicrotubule organizing center attachment site

SYNE1 SYNE2

2.77e-03111522GO:0034992
GeneOntologyCellularComponentcohesin complex

RAD21L1 RAD21

2.77e-03111522GO:0008278
GeneOntologyCellularComponentmeiotic nuclear membrane microtubule tethering complex

SYNE1 SYNE2

2.77e-03111522GO:0034993
GeneOntologyCellularComponenttranscription export complex

THOC1 THOC2

3.30e-03121522GO:0000346
GeneOntologyCellularComponentmitotic spindle pole

BCCIP ASPM CDK5RAP2

3.76e-03431523GO:0097431
GeneOntologyCellularComponentsarcoplasmic reticulum

HSP90B1 RYR2 RYR3 SYNE2

3.90e-03881524GO:0016529
GeneOntologyCellularComponentsarcoplasmic reticulum membrane

RYR2 RYR3 SYNE2

4.28e-03451523GO:0033017
GeneOntologyCellularComponentcondensed nuclear chromosome

RAD21L1 SYCP3 NCAPD2 RAD21

4.40e-03911524GO:0000794
GeneOntologyCellularComponentazurophil granule lumen

HEXB GLB1 PADI2 DNAJC3

4.40e-03911524GO:0035578
GeneOntologyCellularComponentsperm flagellum

IFT172 USP26 FSIP2 DNAH17 CFAP58 CFAP57

4.83e-032141526GO:0036126
HumanPhenoAbnormal sperm motility

DNAAF11 CFAP43 ARMC2 USP26 FSIP2 DNAH17 CFAP58 HYDIN CCDC40 DNAH11

1.09e-061156310HP:0012206
HumanPhenoAbnormal sperm physiology

DNAAF11 CFAP43 ARMC2 USP26 FSIP2 DNAH17 CFAP58 HYDIN CCDC40 DNAH11

1.09e-061156310HP:0034809
HumanPhenoReduced sperm motility

CFAP43 ARMC2 USP26 FSIP2 DNAH17 CFAP58 HYDIN CCDC40

1.61e-0669638HP:0012207
HumanPhenoCoiled sperm flagella

CFAP43 ARMC2 USP26 FSIP2 DNAH17 CFAP58

1.98e-0632636HP:0032560
HumanPhenoDecreased fertility in males

ZPBP SYCP3 DNAAF11 CFAP43 ARMC2 USP26 FSIP2 FANCB DNAH17 CFAP58 HYDIN CCDC40 DNAH11

4.31e-062366313HP:0012041
HumanPhenoMale infertility

ZPBP SYCP3 DNAAF11 CFAP43 ARMC2 USP26 FSIP2 DNAH17 CFAP58 HYDIN CCDC40 DNAH11

6.97e-062096312HP:0003251
HumanPhenoAbnormal axonemal organization of respiratory motile cilia

ARMC2 CCDC40 DNAH11

7.15e-064633HP:0012258
HumanPhenoDecreased fertility

ZPBP IFT172 POLR3H SYCP3 DNAAF11 CFAP43 CCDC141 ARMC2 USP26 FSIP2 FANCB DNAH17 CFAP58 HYDIN CCDC40 DNAH11

9.47e-063806316HP:0000144
HumanPhenoAbnormal sperm tail morphology

CFAP43 ARMC2 USP26 FSIP2 DNAH17 CFAP58

1.20e-0543636HP:0012868
HumanPhenoAbnormal sperm morphology

ZPBP CFAP43 ARMC2 USP26 FSIP2 DNAH17 CFAP58

1.38e-0566637HP:0012864
HumanPhenoAbnormal germ cell morphology

ZPBP CFAP43 ARMC2 USP26 FSIP2 DNAH17 CFAP58

1.53e-0567637HP:0012862
HumanPhenoAbnormal male germ cell morphology

ZPBP CFAP43 ARMC2 USP26 FSIP2 DNAH17 CFAP58

1.53e-0567637HP:0012863
HumanPhenoAbsent sperm flagella

CFAP43 ARMC2 FSIP2 DNAH17 CFAP58

1.94e-0528635HP:0032558
HumanPhenoInfertility

ZPBP IFT172 SYCP3 DNAAF11 CFAP43 CCDC141 ARMC2 USP26 FSIP2 DNAH17 CFAP58 HYDIN CCDC40 DNAH11

2.03e-053146314HP:0000789
HumanPhenoShort sperm flagella

CFAP43 USP26 FSIP2 DNAH17 CFAP58

4.48e-0533635HP:0032559
MousePhenoabnormal motile cilium morphology

DYNC2H1 ZPBP IFT172 DNAAF11 CFAP43 ARMC2 FSIP2 DNAH17 CEP70 CFAP58 CC2D2A CFAP57 HYDIN CCDC40 DNAH11

1.18e-0637012615MP:0013206
MousePhenoabnormal cilium morphology

DYNC2H1 ZPBP IFT172 DNAAF11 CFAP43 ARMC2 FSIP2 DNAH17 CEP70 CFAP58 CC2D2A CFAP57 HYDIN CCDC40 DNAH11

8.07e-0643312615MP:0013202
MousePhenocoiled sperm flagellum

ZPBP CFAP43 ARMC2 CEP70 CFAP58 CFAP57

1.94e-05621266MP:0009238
MousePhenoshort sperm flagellum

CFAP43 ARMC2 FSIP2 CEP70 CFAP58 CFAP57

2.12e-05631266MP:0009239
MousePhenoabnormal left-right axis patterning

HSP90B1 DYNC2H1 IFT172 DNAAF11 CC2D2A DNAH11

3.03e-05671266MP:0001706
MousePhenoabnormal motile primary cilium morphology

DYNC2H1 IFT172 CC2D2A CCDC40 DNAH11

4.02e-05431265MP:0004131
MousePhenodecreased germ cell number

RAD21L1 SYCP3 APOB CFAP43 ARMC2 CIT MAP3K4 USP26 FSIP2 FANCB DNAH17 CEP70 ASPM FBXO7 CFAP58 CDK5RAP2 ATM CFAP57

4.29e-0568712618MP:0002209
MousePhenodecreased male germ cell number

RAD21L1 SYCP3 APOB CFAP43 ARMC2 CIT MAP3K4 USP26 FSIP2 FANCB DNAH17 CEP70 ASPM FBXO7 CFAP58 ATM CFAP57

6.03e-0564012617MP:0004901
MousePhenocomplete atrioventricular septal defect

DYNC2H1 IFT172 CC2D2A DNAH11

8.07e-05261264MP:0010413
MousePhenoatrioventricular septal defect

DOCK1 DYNC2H1 IFT172 AP2B1 CC2D2A DNAH11

1.09e-04841266MP:0010412
MousePhenohydrocephaly

IFT172 APOB DNAAF11 CFAP43 PIGU CC2D2A CFAP57 HYDIN CCDC40

1.14e-042091269MP:0001891
MousePhenoabnormal cell motility

DOCK1 ZPBP APOB CFAP43 THOC2 CCDC141 ARMC2 PGGT1B MAP3K4 FSIP2 PARP1 GLB1 DNAH17 SYNE2 PDILT TLR5 ASPM FBXO7 CFAP58 CFAP57

1.22e-0488512620MP:0020846
MousePhenoabnormal respiratory motile cilium morphology

DNAAF11 CFAP43 CC2D2A HYDIN

1.26e-04291264MP:0011050
MousePhenoabnormal atrioventricular septum morphology

DOCK1 DYNC2H1 IFT172 AP2B1 CC2D2A DNAH11

1.32e-04871266MP:0010592
MousePhenoabnormal sperm number

RAD21L1 SYCP3 APOB CFAP43 ARMC2 MAP3K4 USP26 FSIP2 FANCB DNAH17 CEP70 ASPM FBXO7 CFAP58 ATM CFAP57

1.52e-0462412616MP:0002673
MousePhenooligozoospermia

APOB CFAP43 ARMC2 MAP3K4 USP26 FSIP2 FANCB DNAH17 ASPM FBXO7 CFAP58 CFAP57

1.81e-0438412612MP:0002687
MousePhenoimmotile sperm

CFAP43 ARMC2 FBXO7 CFAP58 CFAP57

1.86e-04591265MP:0020869
MousePhenoabnormal brain ventricular system morphology

IFT172 APOB DNAAF11 CFAP43 PIGU ASPM FES CC2D2A CDK5RAP2 CFAP57 HYDIN CCDC40

2.24e-0439312612MP:0002200
MousePhenobiventricular, discordant atrioventricular connection

CC2D2A DNAH11

2.40e-0431262MP:0011510
MousePhenomale infertility

AIMP1 ZPBP RAD21L1 SYCP3 CFAP43 EZH1 ARMC2 MAP3K4 FSIP2 FANCB DNAH17 PDILT CEP70 FBXO7 CFAP58 CDK5RAP2 ATM CFAP57 HYDIN CCDC40

2.88e-0494412620MP:0001925
MousePhenoabnormal male reproductive system physiology

AIMP1 ZPBP RAD21L1 SYCP3 APOB CFAP43 EZH1 ARMC2 CIT MAP3K4 USP26 FSIP2 FANCB DNAH17 PDILT CEP70 ASPM FBXO7 CFAP58 CDK5RAP2 ATM CFAP57 HYDIN CCDC40 RAD21

2.94e-04132912625MP:0003698
MousePhenoasthenozoospermia

ZPBP APOB CFAP43 ARMC2 MAP3K4 FSIP2 DNAH17 ASPM FBXO7 CFAP58 CFAP57

4.29e-0436212611MP:0002675
MousePhenoabnormal spermatogenesis

ZPBP RAD21L1 SYCP3 APOB CFAP43 ARMC2 CIT MAP3K4 USP26 FSIP2 FANCB DNAH17 CEP70 ASPM FBXO7 CFAP58 CDK5RAP2 ATM CFAP57

4.98e-0491012619MP:0001156
DomainARM-type_fold

DOCK1 CAB39 CLASP1 IFT172 TOGARAM1 RICTOR APOB API5 ECPAS ARMC2 RYR3 FOCAD PPP2R5C PPP2R5D PPP2R5E AP2B1 RNPEP ANKAR NCAPD2 ASPM ATM

3.47e-1333914921IPR016024
Domain-

CAB39 CLASP1 TOGARAM1 RICTOR API5 ECPAS ARMC2 PPP2R5C PPP2R5E AP2B1 ANKAR NCAPD2 ASPM

2.68e-08222149131.25.10.10
DomainARM-like

CAB39 CLASP1 TOGARAM1 RICTOR API5 ECPAS ARMC2 PPP2R5C PPP2R5E AP2B1 ANKAR NCAPD2 CEP70 ASPM

3.55e-0827014914IPR011989
DomainSpectrin_repeat

SYNE1 CCDC141 PPL SYNE2 MACF1 UTRN

9.51e-08291496IPR002017
DomainPkinase_C

ROCK2 CDC42BPA SGK1 CIT SGK3 PRKCG

4.42e-07371496IPR017892
DomainSpectrin

SYNE1 CCDC141 SYNE2 MACF1 UTRN

9.05e-07231495PF00435
DomainPkinase_C

ROCK2 CDC42BPA SGK1 CIT SGK3 PRKCG

9.65e-07421496PF00433
DomainPP2A_B56

PPP2R5C PPP2R5D PPP2R5E

4.92e-0651493IPR002554
DomainB56

PPP2R5C PPP2R5D PPP2R5E

4.92e-0651493PF01603
DomainSPEC

SYNE1 PPL SYNE2 MACF1 UTRN

5.11e-06321495SM00150
DomainSpectrin/alpha-actinin

SYNE1 PPL SYNE2 MACF1 UTRN

5.11e-06321495IPR018159
DomainAGC-kinase_C

ROCK2 CDC42BPA SGK1 CIT SGK3 PRKCG

5.45e-06561496IPR000961
DomainAGC_KINASE_CTER

ROCK2 CDC42BPA SGK1 CIT SGK3 PRKCG

5.45e-06561496PS51285
DomainS_TK_X

ROCK2 CDC42BPA SGK1 CIT SGK3 PRKCG

5.45e-06561496SM00133
DomainProtein_kinase_ATP_BS

TNIK ROCK2 CDC42BPA SGK1 CIT MAP3K4 SGK3 MYO3A FER FES PRKCG STK39 DYRK3

1.12e-0537914913IPR017441
DomainCH

IQGAP2 SYNE1 SYNE2 ASPM MACF1 UTRN

1.31e-05651496SM00033
DomainCH

IQGAP2 SYNE1 SYNE2 ASPM MACF1 UTRN

2.01e-05701496PF00307
Domain-

IQGAP2 SYNE1 SYNE2 ASPM MACF1 UTRN

2.18e-057114961.10.418.10
DomainCH

IQGAP2 SYNE1 SYNE2 ASPM MACF1 UTRN

2.55e-05731496PS50021
DomainKinase-like_dom

TNIK ROCK2 CDC42BPA SGK1 CIT MAP3K4 SGK3 MYO3A FER FES MACF1 PRKCG STK39 ATM DYRK3

2.94e-0554214915IPR011009
DomainCH-domain

IQGAP2 SYNE1 SYNE2 ASPM MACF1 UTRN

2.98e-05751496IPR001715
DomainACTININ_2

SYNE1 SYNE2 MACF1 UTRN

3.06e-05231494PS00020
DomainACTININ_1

SYNE1 SYNE2 MACF1 UTRN

3.06e-05231494PS00019
DomainActinin_actin-bd_CS

SYNE1 SYNE2 MACF1 UTRN

3.06e-05231494IPR001589
DomainASH

ASPM HYDIN

6.32e-0521492IPR031549
DomainASH

ASPM HYDIN

6.32e-0521492PF15780
DomainTyr-prot_kinase_Fes/Fps

FER FES

6.32e-0521492IPR016250
DomainPROTEIN_KINASE_ATP

TNIK ROCK2 CDC42BPA SGK1 CIT MAP3K4 SGK3 MYO3A FER FES PRKCG STK39 DYRK3

8.11e-0545914913PS00107
DomainSer/Thr_kinase_AS

TNIK ROCK2 CDC42BPA SGK1 CIT MAP3K4 SGK3 MYO3A PRKCG STK39 DYRK3

1.40e-0435714911IPR008271
DomainS_TKc

TNIK ROCK2 CDC42BPA SGK1 CIT MAP3K4 SGK3 MYO3A PRKCG STK39 DYRK3

1.47e-0435914911SM00220
DomainProt_kinase_dom

TNIK ROCK2 CDC42BPA SGK1 CIT MAP3K4 SGK3 MYO3A FER FES PRKCG STK39 DYRK3

1.52e-0448914913IPR000719
DomainPROTEIN_KINASE_ST

TNIK ROCK2 CDC42BPA SGK1 CIT MAP3K4 SGK3 MYO3A PRKCG STK39 DYRK3

1.59e-0436214911PS00108
DomainPROTEIN_KINASE_DOM

TNIK ROCK2 CDC42BPA SGK1 CIT MAP3K4 SGK3 MYO3A FER FES PRKCG STK39 DYRK3

1.65e-0449314913PS50011
DomainDynein_heavy_chain_D4_dom

DNAH3 DYNC2H1 DNAH11

1.70e-04141493IPR024317
DomainDynein_HC_stalk

DNAH3 DYNC2H1 DNAH11

1.70e-04141493IPR024743
DomainDynein_heavy_dom-2

DNAH3 DYNC2H1 DNAH11

1.70e-04141493IPR013602
DomainDHC_N2

DNAH3 DYNC2H1 DNAH11

1.70e-04141493PF08393
DomainATPase_dyneun-rel_AAA

DNAH3 DYNC2H1 DNAH11

1.70e-04141493IPR011704
DomainMT

DNAH3 DYNC2H1 DNAH11

1.70e-04141493PF12777
DomainAAA_8

DNAH3 DYNC2H1 DNAH11

1.70e-04141493PF12780
DomainCNH

TNIK CDC42BPA CIT

1.70e-04141493SM00036
DomainAAA_5

DNAH3 DYNC2H1 DNAH11

1.70e-04141493PF07728
DomainRad21/Rec8_C_eu

RAD21L1 RAD21

1.89e-0431492IPR006909
DomainRad21_Rec8_N

RAD21L1 RAD21

1.89e-0431492IPR006910
DomainRad21_Rec8_N

RAD21L1 RAD21

1.89e-0431492PF04825
DomainRad21_Rec8

RAD21L1 RAD21

1.89e-0431492PF04824
DomainRyanodine_rcpt

RYR2 RYR3

1.89e-0431492IPR003032
DomainRad21/Rec8_C

RAD21L1 RAD21

1.89e-0431492IPR023093
Domain-

RAD21L1 RAD21

1.89e-04314921.10.10.580
DomainRyanrecept_TM4-6

RYR2 RYR3

1.89e-0431492IPR009460
DomainRyR

RYR2 RYR3

1.89e-0431492PF02026
DomainRR_TM4-6

RYR2 RYR3

1.89e-0431492PF06459
DomainRyan_recept

RYR2 RYR3

1.89e-0431492IPR013333
DomainDHC_fam

DNAH3 DYNC2H1 DNAH11

2.11e-04151493IPR026983
DomainDynein_heavy

DNAH3 DYNC2H1 DNAH11

2.11e-04151493PF03028
DomainCNH

TNIK CDC42BPA CIT

2.11e-04151493PF00780
DomainDynein_heavy_dom

DNAH3 DYNC2H1 DNAH11

2.11e-04151493IPR004273
DomainCNH

TNIK CDC42BPA CIT

2.11e-04151493PS50219
DomainCNH_dom

TNIK CDC42BPA CIT

2.11e-04151493IPR001180
DomainPkinase

TNIK ROCK2 CDC42BPA SGK1 CIT MAP3K4 SGK3 MYO3A PRKCG STK39 DYRK3

2.47e-0438114911PF00069
DomainKASH

SYNE1 SYNE2

3.75e-0441492IPR012315
DomainKASH

SYNE1 SYNE2

3.75e-0441492PS51049
DomainKASH

SYNE1 SYNE2

3.75e-0441492SM01249
DomainKASH

SYNE1 SYNE2

3.75e-0441492PF10541
DomainSPRY

TRIM25 RYR2 RYR3 TRIM16 TRIM16L

6.60e-04871495SM00449
DomainRIH_assoc-dom

RYR2 RYR3

9.29e-0461492IPR013662
DomainIns145_P3_rec

RYR2 RYR3

9.29e-0461492PF08709
DomainRIH_assoc

RYR2 RYR3

9.29e-0461492PF08454
DomainRIH_dom

RYR2 RYR3

9.29e-0461492IPR000699
DomainIns145_P3_rcpt

RYR2 RYR3

9.29e-0461492IPR014821
DomainRyanodine_recept-rel

RYR2 RYR3

9.29e-0461492IPR015925
Domain-

RYR2 RYR3

9.29e-04614921.25.10.30
DomainRYDR_ITPR

RYR2 RYR3

9.29e-0461492PF01365
DomainSPRY

TRIM25 RYR2 RYR3 TRIM16 TRIM16L

9.38e-04941495PF00622
DomainSPRY_dom

TRIM25 RYR2 RYR3 TRIM16 TRIM16L

9.38e-04941495IPR003877
DomainC2

WWC3 INPP4B CC2D2A PRKCG PLCB3 WWC1

9.79e-041421496PS50004
DomainB30.2/SPRY

TRIM25 RYR2 RYR3 TRIM16 TRIM16L

9.84e-04951495IPR001870
DomainB302_SPRY

TRIM25 RYR2 RYR3 TRIM16 TRIM16L

9.84e-04951495PS50188
DomainHR1_rho-bd

CDC42BPA CEP70 CFAP58

1.01e-03251493IPR011072
DomainC1_1

ROCK2 CDC42BPA CIT PRKCG

1.11e-03571494PF00130
DomainHEAT

CLASP1 TOGARAM1 ECPAS NCAPD2

1.18e-03581494IPR000357
Domain-

WWC3 INPP4B CC2D2A PRKCG PLCB3 WWC1

1.21e-0314814962.60.40.150
DomainPlectin

PPL MACF1

1.29e-0371492PF00681
DomainPlectin_repeat

PPL MACF1

1.29e-0371492IPR001101
DomainPLEC

PPL MACF1

1.29e-0371492SM00250
DomainZF_DAG_PE_1

ROCK2 CDC42BPA CIT PRKCG

1.71e-03641494PS00479
DomainZF_DAG_PE_2

ROCK2 CDC42BPA CIT PRKCG

1.71e-03641494PS50081
DomainDHC_N1

DYNC2H1 DNAH11

1.72e-0381492PF08385
DomainDynein_heavy_dom-1

DYNC2H1 DNAH11

1.72e-0381492IPR013594
DomainPH

ROCK2 CDC42BPA TBC1D2B ALS2 CIT ARHGAP20 FERMT2 ACAP3

1.78e-032781498SM00233
DomainC1

ROCK2 CDC42BPA CIT PRKCG

1.81e-03651494SM00109
DomainPH_DOMAIN

ROCK2 CDC42BPA TBC1D2B ALS2 CIT ARHGAP20 FERMT2 ACAP3

1.82e-032791498PS50003
DomainPH_domain

ROCK2 CDC42BPA TBC1D2B ALS2 CIT ARHGAP20 FERMT2 ACAP3

1.86e-032801498IPR001849
DomainPE/DAG-bd

ROCK2 CDC42BPA CIT PRKCG

1.91e-03661494IPR002219
DomainC2_dom

WWC3 INPP4B CC2D2A PRKCG PLCB3 WWC1

2.04e-031641496IPR000008
DomainIQ

MYH6 IQGAP2 MYO3A ASPM

2.50e-03711494PF00612
DomainMIR

RYR2 RYR3

2.73e-03101492PF02815
DomainMIR_motif

RYR2 RYR3

2.73e-03101492IPR016093
DomainVPS9

GAPVD1 ALS2

2.73e-03101492PS51205
DomainMIR

RYR2 RYR3

2.73e-03101492PS50919
PathwayREACTOME_PLATELET_SENSITIZATION_BY_LDL

APOB PPP2R5C PPP2R5D PPP2R5E

6.92e-06171074MM15096
PathwayREACTOME_PLATELET_SENSITIZATION_BY_LDL

APOB PPP2R5C PPP2R5D PPP2R5E

6.92e-06171074M919
PathwayKEGG_MEDICUS_REFERENCE_CONDENSIN_LOADING

PPP2R5C PPP2R5D PPP2R5E NCAPD2

1.38e-05201074M47876
PathwayWP_IL6_SIGNALING_PATHWAY

SGK1 MAP3K4 PPP2R5C PPP2R5D PPP2R5E FES

1.11e-041001076MM15826
PathwayWP_COHESIN_COMPLEX_CORNELIA_DE_LANGE_SYNDROME

PPP2R5C PPP2R5D PPP2R5E RAD21

1.22e-04341074M42555
PathwayREACTOME_MITOTIC_PROMETAPHASE

CLASP1 PPP2R5C PPP2R5D PPP2R5E NCAPD2 CEP70 CDK5RAP2 RAD21

1.50e-042021078MM15362
PathwayREACTOME_REGULATION_OF_TP53_DEGRADATION

SGK1 RICTOR PPP2R5C ATM

1.53e-04361074MM15339
PathwayREACTOME_MITOTIC_PROMETAPHASE

CLASP1 PPP2R5C PPP2R5D PPP2R5E NCAPD2 CEP70 CDK5RAP2 RAD21

1.60e-042041078M4217
PathwayREACTOME_REGULATION_OF_TP53_EXPRESSION_AND_DEGRADATION

SGK1 RICTOR PPP2R5C ATM

1.71e-04371074M27641
PathwayREACTOME_SIGNALING_BY_CTNNB1_PHOSPHO_SITE_MUTANTS

PPP2R5C PPP2R5D PPP2R5E

1.81e-04151073M27407
PathwayWP_G13_SIGNALING

ROCK2 IQGAP2 CIT MAP3K4

1.90e-04381074M39606
PathwayWP_G13_SIGNALING_PATHWAY

ROCK2 IQGAP2 CIT MAP3K4

2.10e-04391074MM15898
PathwayKEGG_MEDICUS_REFERENCE_COHESIN_DISSOCIATION_IN_PROPHASE

PPP2R5C PPP2R5D PPP2R5E

2.22e-04161073M47870
PathwayWP_DEGRADATION_PATHWAY_OF_SPHINGOLIPIDS_INCLUDING_DISEASES

HEXB GLB1 SCARB2

2.68e-04171073M39638
PathwayREACTOME_BETA_CATENIN_PHOSPHORYLATION_CASCADE

PPP2R5C PPP2R5D PPP2R5E

2.68e-04171073M27083
PathwayREACTOME_BETA_CATENIN_PHOSPHORYLATION_CASCADE

PPP2R5C PPP2R5D PPP2R5E

3.19e-04181073MM14759
PathwayKEGG_MEDICUS_REFERENCE_PP2A_AKT_SIGNALING_PATHWAY

PPP2R5C PPP2R5D PPP2R5E

3.77e-04191073M47525
PathwayREACTOME_RAC1_GTPASE_CYCLE

DOCK1 CDC42BPA IQGAP2 ALS2 CIT ARHGAP20 FERMT2

5.01e-041841077M41809
PathwayWP_CILIOPATHIES

DYNC2H1 IFT172 DNAAF11 CC2D2A HYDIN CCDC40 DNAH11

5.01e-041841077M39880
PathwayREACTOME_CTLA4_INHIBITORY_SIGNALING

PPP2R5C PPP2R5D PPP2R5E

5.12e-04211073M5876
PathwayREACTOME_CTLA4_INHIBITORY_SIGNALING

PPP2R5C PPP2R5D PPP2R5E

5.12e-04211073MM14996
PathwayKEGG_MEDICUS_REFERENCE_KERATAN_SULFATE_DEGRADATION

HEXB GLB1

5.62e-0451072M47609
PathwayWP_PKCGAMMA_CALCIUM_SIGNALING_IN_ATAXIA

RYR3 PRKCG PLCB3

5.89e-04221073M39795
PathwayKEGG_MEDICUS_REFERENCE_CD80_CD86_CTLA4_PP2A_SIGNALING_PATHWAY

PPP2R5C PPP2R5D PPP2R5E

5.89e-04221073M47919
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

TNIK HSP90B1 FAM184A TRIM25 CDC42BPA PDHA1 DYNC2H1 DNAJC16 SYNE1 BCCIP RICTOR RPS23 PIGU PARP1 NOP58 PPP2R5D GLB1 SYNE2 POP1 ASPM CDK5RAP2 MACF1 TTC17 ATM FERMT2 DNAJC3 RAD21

5.83e-1014871562733957083
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

GAPVD1 CDC42BPA VPS13C TBC1D2B INO80 ECPAS PPP2R5C NRXN2 NCAPD2 CDK5RAP2 ARHGAP20 PADI2 ACAP3 SMG6 RAD21

1.87e-085291561514621295
Pubmed

A high-throughput approach for measuring temporal changes in the interactome.

PDXDC1 HEXB ROCK2 HSP90B1 GAPVD1 AIMP1 PDHA1 BCCIP RPS23 API5 ECPAS PGGT1B CUL5 TRIM16 PPP2R5C PPP2R5D PPP2R5E AP2B1 POP1 NCAPD2 MACF1 STK39 PLCB3 FERMT2

3.68e-0814551562422863883
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

TNIK CLASP1 DNAJC16 IFT172 SYNE1 ALS2 MAP3K4 FOCAD PPP2R5E GCC2 SPHKAP MACF1 LARGE1

4.39e-084071561312693553
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

HEXB ROCK2 CAB39 HSP90B1 MYH6 TRIM25 CLASP1 IQGAP2 PDHA1 SYNE1 RPS23 CIT CUL5 PARP1 PPP2R5E NRXN2 AP2B1 RNPEP MACF1 PRKCG FERMT2 UTRN DNAH11

1.16e-0714311562337142655
Pubmed

The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.

PDXDC1 HSP90B1 GAPVD1 AIMP1 DNAJC16 IFT172 RPS23 API5 ECPAS THOC2 PARP1 NOP58 AP2B1 NCAPD2 RAD21

2.12e-076381561533239621
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

GAPVD1 PDHA1 RPS23 ECPAS THOC2 NOP58 AP2B1 RNPEP SYNE2 POP1 NCAPD2 MACF1 ATM UTRN RAD21

2.85e-076531561522586326
Pubmed

The protein network surrounding the human telomere repeat binding factors TRF1, TRF2, and POT1.

HSP90B1 SYNE1 RYR2 SYNE2 CFAP58 MACF1 ARHGAP20 FBXO21 UTRN

2.91e-07197156920811636
Pubmed

Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.

DNAH3 DYNC2H1 DNAH17 DNAH11

3.76e-071415649373155
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

THOC1 HSP90B1 GAPVD1 TRIM25 AIMP1 PDHA1 DYNC2H1 VPS13C SYNE1 BCCIP APOB RPS23 API5 ECPAS THOC2 PARP1 NOP58 RNPEP NCAPD2 CC2D2A ATM RAD21

4.45e-0714251562230948266
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

PDXDC1 TDRD15 GAPVD1 CDC42BPA IQGAP2 DNAJC16 VPS13C MAGEC3 RICTOR APOB PPL RYR2 GCC2 CDK5RAP2 FERMT2 MGA

4.81e-077771561635844135
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

ROCK2 HSP90B1 MYH6 IQGAP2 SYNE1 APOB CAGE1 RPS23 BANF1 PPL RYR2 TRIM16 PARP1 AP2B1 SYNE2 NCAPD2 ASPM CC2D2A MACF1 ATM DNAJC3 PCID2

5.42e-0714421562235575683
Pubmed

Assignment of human protein phosphatase 2A regulatory subunit genes b56alpha, b56beta, b56gamma, b56delta, and b56epsilon (PPP2R5A-PPP2R5E), highly expressed in muscle and brain, to chromosome regions 1q41, 11q12, 3p21, 6p21.1, and 7p11.2 --> p12.

PPP2R5C PPP2R5D PPP2R5E

8.79e-07515638812429
Pubmed

Genomic organisation, chromosomal localisation tissue distribution and developmental regulation of the PR61/B' regulatory subunits of protein phosphatase 2A in mice.

PPP2R5C PPP2R5D PPP2R5E

8.79e-075156315095873
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

TNIK DNAJC16 SYNE1 TOGARAM1 ALS2 NRXN2 SYNE2 MACF1 SMG6

8.85e-07225156912168954
Pubmed

LncRNAs-directed PTEN enzymatic switch governs epithelial-mesenchymal transition.

TDRD15 PDHA1 SYNE1 ARMC2 RYR2 RYR3 FSIP2 FSBP

9.91e-07168156830631154
Pubmed

Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.

PDXDC1 HEXB TNIK ROCK2 HSP90B1 BCCIP APOB RPS23 PARP1 PPP2R5D GLB1 AP2B1 RNPEP SCARB2 SYNE2 POP1 MACF1 TTC17 DNAJC3 PCID2

1.59e-0612971562033545068
Pubmed

A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.

PDXDC1 IQGAP2 ECPAS PPP2R5C PPP2R5D PPP2R5E AP2B1 RNPEP SCARB2 NCAPD2 CPVL PCID2 RAD21

1.63e-065601561335241646
Pubmed

Analysis of interaction partners for eukaryotic translation elongation factor 1A M-domain by functional proteomics.

IFT172 SYNE1 DNAH17 MACF1

1.78e-0620156421689717
Pubmed

ZZW-115-dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents.

THOC1 TRIM25 PDHA1 RPS23 API5 THOC2 CIT BANF1 PARP1 NOP58 GLB1 AP2B1 MACF1 PCID2

1.84e-066601561432780723
Pubmed

A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.

PDXDC1 ROCK2 GAPVD1 TRIM25 CLASP1 DNAJC16 IFT172 ECPAS PPL AP2B1 TTC17 FBXO21 PADI2 CPVL UTRN DNAJC3 WWC1

2.00e-069741561728675297
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

ROCK2 GAPVD1 CLASP1 IQGAP2 AIMP1 DYNC2H1 IFT172 DNAAF11 PIGU POSTN FANCB PPP2R5C PPP2R5D PPP2R5E GLB1 AP2B1 GCC2 FERMT2 CCDC40 LARGE1

2.10e-0613211562027173435
Pubmed

Impaired plasma membrane localization of ubiquitin ligase complex underlies 3-M syndrome development.

FAM184A AIMP1 APOB CFAP43 MIDEAS NOP58 GLB1 GCC2 POP1 MACF1 PLCB3 LARGE1

2.73e-064961561231343991
Pubmed

The B56 family of protein phosphatase 2A (PP2A) regulatory subunits encodes differentiation-induced phosphoproteins that target PP2A to both nucleus and cytoplasm.

PPP2R5C PPP2R5D PPP2R5E

3.06e-06715638703017
Pubmed

MRCKα is activated by caspase cleavage to assemble an apical actin ring for epithelial cell extrusion.

ROCK2 CDC42BPA CIT

3.06e-067156329162624
Pubmed

Identification of a new family of protein phosphatase 2A regulatory subunits.

PPP2R5C PPP2R5D PPP2R5E

3.06e-06715637592815
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

FAM184A TRIM25 CDC42BPA CLASP1 DNAJC16 SYNE1 RICTOR INO80 API5 CIT BANF1 PPP2R5C PPP2R5E MTRFR POP1 NCAPD2 MACF1 UTRN PCID2 SMG6 RAD21

3.76e-0614971562131527615
Pubmed

Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.

PDXDC1 HSP90B1 TRIM25 DYNC2H1 SYNE1 RICTOR RPS23 ECPAS PARP1 NOP58 AP2B1 POP1 MACF1 UTRN HYDIN

3.90e-068071561530575818
Pubmed

LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.

DOCK1 TRIM25 CDC42BPA RICTOR ECPAS CIT NCAPD2 TTC17

3.92e-06202156833005030
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

TNIK HSP90B1 TUT4 CDC42BPA AIMP1 PDHA1 DNAJC16 RICTOR RPS23 CIT VPS37B RYR2 PPP2R5C PPP2R5D SPHKAP MACF1 PRKCG FERMT2

3.93e-0611391561836417873
Pubmed

Cilia gene mutations cause atrioventricular septal defects by multiple mechanisms.

DYNC2H1 IFT172 CC2D2A DNAH11

4.58e-0625156427340223
Pubmed

Network organization of the human autophagy system.

DOCK1 CAB39 KRT4 HSP90B1 IQGAP2 PDHA1 TBC1D2B ECPAS PARP1 CPVL UTRN

4.95e-064371561120562859
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

HEXB HSP90B1 IFT172 SYNE1 CIT CCDC85A RYR3 FOCAD PARP1 PPP2R5E AP2B1 CEP70 FBXO7 MACF1 TTC17 ANKRD36 ATM PADI2 UTRN

5.40e-0612851561935914814
Pubmed

A protein interaction landscape of breast cancer.

THOC1 CAB39 GAPVD1 TRIM25 AIMP1 TMTC2 ECPAS EZH1 PARP1 GLB1 AP2B1 MACF1 RAD21

6.26e-066341561334591612
Pubmed

The cohesin subunit RAD21L functions in meiotic synapsis and exhibits sexual dimorphism in fertility.

RAD21L1 SYCP3 RAD21

7.29e-069156321743440
Pubmed

De Novo Mutations Affecting the Catalytic Cα Subunit of PP2A, PPP2CA, Cause Syndromic Intellectual Disability Resembling Other PP2A-Related Neurodevelopmental Disorders.

PPP2R5C PPP2R5D PPP2R5E

7.29e-069156330595372
Pubmed

Direct binding between BubR1 and B56-PP2A phosphatase complexes regulate mitotic progression.

PPP2R5C PPP2R5D PPP2R5E

7.29e-069156323345399
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

TNIK ROCK2 CLASP1 IQGAP2 SYNE1 CIT PARP1 PPP2R5D AP2B1 SPHKAP SYNE2 CDK5RAP2 MACF1 PRKCG MGA SMG6

7.53e-069631561628671696
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

GAPVD1 IQGAP2 RICTOR ALS2 APOB INO80 THOC2 PGGT1B PPP2R5C PPP2R5E POP1 FBXO7 CDK5RAP2 MACF1 FERMT2 MGA UTRN

8.19e-0610841561711544199
Pubmed

RAD21L, a novel cohesin subunit implicated in linking homologous chromosomes in mammalian meiosis.

RAD21L1 SYCP3 RAD21

1.04e-0510156321242291
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

THOC1 ROCK2 GAPVD1 CLASP1 PDHA1 RICTOR ECPAS THOC2 PPL TRIM16 MYO3A POP1 PLCB3 ATM

1.13e-057741561415302935
Pubmed

USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.

CDC42BPA DNAJC16 SYNE1 THOC2 PARP1 POP1 ASPM MACF1

1.15e-05234156836243803
Pubmed

WDR76 Co-Localizes with Heterochromatin Related Proteins and Rapidly Responds to DNA Damage.

HSP90B1 AIMP1 INO80 MIDEAS PARP1 NOP58 AP2B1 POP1 UTRN RAD21

1.26e-053941561027248496
Pubmed

Primary Ciliary Dyskinesia

DNAAF11 HYDIN CCDC40 DNAH11

1.27e-0532156420301301
Pubmed

Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.

THOC1 ROCK2 HSP90B1 GAPVD1 CDC42BPA WWC3 PDHA1 RPS23 API5 THOC2 CIT PARP1 NOP58 AP2B1 POP1 MGA PCID2 WWC1

1.34e-0512471561827684187
Pubmed

A conserved KASH domain protein associates with telomeres, SUN1, and dynactin during mammalian meiosis.

SYNE1 SYCP3 SYNE2

1.42e-0511156322826121
Pubmed

A comprehensive proteomics-based interaction screen that links DYRK1A to RNF169 and to the DNA damage response.

MYH6 CIT PPL AP2B1 FERMT2 UTRN

1.61e-05118156630979931
Pubmed

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.

CAB39 MYH6 GAPVD1 CDC42BPA CLASP1 SGK1 ANKRD36C MAP3K4 SGK3 TRIM16 AP2B1 FER CDK5RAP2 ANKRD36 UTRN

1.61e-059101561536736316
Pubmed

A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.

CAB39 CDC42BPA SYNE1 LRRC2 CCDC141 PPP2R5E SYNE2 CDK5RAP2 MACF1 MGA UTRN

1.65e-054971561123414517
Pubmed

Fibril treatment changes protein interactions of tau and α-synuclein in human neurons.

TNIK ROCK2 CLASP1 IQGAP2 API5 ECPAS PARP1 PPP2R5C SYNE2 MACF1 FERMT2

1.68e-054981561136634849
Pubmed

Exploring an Alternative Cysteine-Reactive Chemistry to Enable Proteome-Wide PPI Analysis by Cross-Linking Mass Spectrometry.

TUT4 BCCIP RPS23 FOCAD PARP1 PPP2R5C PPP2R5E AP2B1 NCAPD2 UTRN

1.81e-054111561036652389
Pubmed

Meiotic cohesin complexes are essential for the formation of the axial element in mice.

RAD21L1 SYCP3 RAD21

1.89e-0512156322711701
Pubmed

A new meiosis-specific cohesin complex implicated in the cohesin code for homologous pairing.

RAD21L1 SYCP3 RAD21

1.89e-0512156321274006
Pubmed

Regulation of Chk2 phosphorylation by interaction with protein phosphatase 2A via its B' regulatory subunit.

PPP2R5C PPP2R5D PPP2R5E

1.89e-0512156315380617
Pubmed

Protein phosphatase 2A protects centromeric sister chromatid cohesion during meiosis I.

PPP2R5C PPP2R5D PPP2R5E

1.89e-0512156316541024
Pubmed

Large-scale mapping of human protein-protein interactions by mass spectrometry.

PDXDC1 ROCK2 CAB39 GAPVD1 CLASP1 IQGAP2 PDHA1 SGK1 BCCIP ALS2 ECPAS CUL5 GLB1 AP2B1 ASPM FES CPVL PCID2

1.98e-0512841561817353931
Pubmed

Fer kinase limits neutrophil chemotaxis toward end target chemoattractants.

FER FES

2.00e-052156223355730
Pubmed

Lysosomal β-galactosidase and β-hexosaminidase activities correlate with clinical stages of dementia associated with Alzheimer's disease and type 2 diabetes mellitus.

HEXB GLB1

2.00e-052156221321400
Pubmed

Ubiquitin modification of serum and glucocorticoid-induced protein kinase-1 (SGK-1).

SGK1 SGK3

2.00e-052156212218062
Pubmed

Ataxia telangiectasia mutated (ATM) signaling network is modulated by a novel poly(ADP-ribose)-dependent pathway in the early response to DNA-damaging agents.

PARP1 ATM

2.00e-052156217428792
Pubmed

ASPM and citron kinase co-localize to the midbody ring during cytokinesis.

CIT ASPM

2.00e-052156217534152
Pubmed

Nesprins: a novel family of spectrin-repeat-containing proteins that localize to the nuclear membrane in multiple tissues.

SYNE1 SYNE2

2.00e-052156211792814
Pubmed

Bis(monoacylglycero)phosphate: a secondary storage lipid in the gangliosidoses.

HEXB GLB1

2.00e-052156225795792
Pubmed

Nesprin-1 and nesprin-2 regulate endothelial cell shape and migration.

SYNE1 SYNE2

2.00e-052156224931616
Pubmed

C-terminal phosphorylation of SPAK and OSR1 kinases promotes their binding and activation by the scaffolding protein MO25.

CAB39 STK39

2.00e-052156230060950
Pubmed

Fps/Fes and Fer non-receptor protein-tyrosine kinases regulate collagen- and ADP-induced platelet aggregation.

FER FES

2.00e-052156212871378
Pubmed

Poly(ADP-ribose) polymerase activity is not affected in ataxia telangiectasia cells and knockout mice.

PARP1 ATM

2.00e-05215629934867
Pubmed

Closing in on the biological functions of Fps/Fes and Fer.

FER FES

2.00e-052156211994747
Pubmed

Positional cloning reveals strain-dependent expression of Trim16 to alter susceptibility to bleomycin-induced pulmonary fibrosis in mice.

TRIM16 TRIM16L

2.00e-052156223341783
Pubmed

The estrogen-responsive B box protein: a novel regulator of keratinocyte differentiation.

TRIM16 TRIM16L

2.00e-052156211919186
Pubmed

FER and FES tyrosine kinase fusions in follicular T-cell lymphoma.

FER FES

2.00e-052156231746983
Pubmed

Poly(ADP-ribose) polymerase-1 inhibits ATM kinase activity in DNA damage response.

PARP1 ATM

2.00e-052156215178448
Pubmed

Tissue-specific alternative splicing of mouse brain type ryanodine receptor/calcium release channel mRNA.

RYR2 RYR3

2.00e-05215628898078
Pubmed

The mouse sino-atrial node expresses both the type 2 and type 3 Ca(2+) release channels/ryanodine receptors.

RYR2 RYR3

2.00e-052156214550562
Pubmed

Heterozygous loss of keratinocyte TRIM16 expression increases melanocytic cell lesions and lymph node metastasis.

TRIM16 TRIM16L

2.00e-052156231342168
Pubmed

The E3 Ligase TRIM16 Is a Key Suppressor of Pathological Cardiac Hypertrophy.

TRIM16 TRIM16L

2.00e-052156235437018
Pubmed

TRIM16 protects from OGD/R-induced oxidative stress in cultured hippocampal neurons by enhancing Nrf2/ARE antioxidant signaling via downregulation of Keap1.

TRIM16 TRIM16L

2.00e-052156232251645
Pubmed

Neurochemical, morphological, and neurophysiological abnormalities in retinas of Sandhoff and GM1 gangliosidosis mice.

HEXB GLB1

2.00e-052156217442056
Pubmed

Human microcephaly ASPM protein is a spindle pole-focusing factor that functions redundantly with CDK5RAP2.

ASPM CDK5RAP2

2.00e-052156228883092
Pubmed

CAMDI interacts with the human memory-associated protein KIBRA and regulates AMPAR cell surface expression and cognition.

CCDC141 WWC1

2.00e-052156231730661
Pubmed

Multiple novel nesprin-1 and nesprin-2 variants act as versatile tissue-specific intracellular scaffolds.

SYNE1 SYNE2

2.00e-052156222768332
Pubmed

Phosphorylation-Dependent Regulation of the DNA Damage Response of Adaptor Protein KIBRA in Cancer Cells.

ATM WWC1

2.00e-052156226929199
Pubmed

Early embryonic lethality in PARP-1 Atm double-mutant mice suggests a functional synergy in cell proliferation during development.

PARP1 ATM

2.00e-052156211238919
Pubmed

Altered ryanodine receptor expression in mild cognitive impairment and Alzheimer's disease.

RYR2 RYR3

2.00e-052156221531043
Pubmed

Modulation of calcium signalling by dominant negative splice variant of ryanodine receptor subtype 3 in native smooth muscle cells.

RYR2 RYR3

2.00e-052156216678258
Pubmed

Chromosomal mapping of two members of the human dynein gene family to chromosome regions 7p15 and 11q13 near the deafness loci DFNA 5 and DFNA 11.

DYNC2H1 DNAH11

2.00e-05215629325061
Pubmed

Glycohydrolases β-hexosaminidase and β-galactosidase are associated with lipid microdomains of Jurkat T-lymphocytes.

HEXB GLB1

2.00e-052156221978926
Pubmed

Involvement of the cohesin Rad21 and SCP3 in monopolar attachment of sister kinetochores during mouse meiosis I.

SYCP3 RAD21

2.00e-052156214970259
Pubmed

Syne-1 and Syne-2 play crucial roles in myonuclear anchorage and motor neuron innervation.

SYNE1 SYNE2

2.00e-052156217267447
Pubmed

Fps/Fes and Fer protein-tyrosinekinases play redundant roles in regulating hematopoiesis.

FER FES

2.00e-052156212901971
Pubmed

Nesprins: tissue-specific expression of epsilon and other short isoforms.

SYNE1 SYNE2

2.00e-052156224718612
Pubmed

Targeted ablation of nesprin 1 and nesprin 2 from murine myocardium results in cardiomyopathy, altered nuclear morphology and inhibition of the biomechanical gene response.

SYNE1 SYNE2

2.00e-052156224586179
Pubmed

The AGC kinase SGK1 regulates TH1 and TH2 differentiation downstream of the mTORC2 complex.

SGK1 RICTOR

2.00e-052156224705297
Pubmed

Interaction between ATM and PARP-1 in response to DNA damage and sensitization of ATM deficient cells through PARP inhibition.

PARP1 ATM

2.00e-052156217459151
Pubmed

Tripartite motif 16 ameliorates nonalcoholic steatohepatitis by promoting the degradation of phospho-TAK1.

TRIM16 TRIM16L

2.00e-052156234146477
Pubmed

Nesprin-1 and -2 are involved in the pathogenesis of Emery Dreifuss muscular dystrophy and are critical for nuclear envelope integrity.

SYNE1 SYNE2

2.00e-052156217761684
Pubmed

INPP4B is upregulated and functions as an oncogenic driver through SGK3 in a subset of melanomas.

INPP4B SGK3

2.00e-052156226573229
Pubmed

Nesprin-1-alpha2 associates with kinesin at myotube outer nuclear membranes, but is restricted to neuromuscular junction nuclei in adult muscle.

SYNE1 SYNE2

2.00e-052156231578382
Pubmed

Activation of Na+/K+-ATPase by the serum and glucocorticoid-dependent kinase isoforms.

SGK1 SGK3

2.00e-052156212590200
Pubmed

Condensin I recruitment to base damage-enriched DNA lesions is modulated by PARP1.

PARP1 NCAPD2

2.00e-052156221858164
InteractionLURAP1 interactions

ROCK2 CDC42BPA TBC1D2B CCDC112 PPP2R5D ASPM CDK5RAP2 MGA UTRN

1.09e-061371549int:LURAP1
InteractionCIT interactions

THOC1 TNIK HSP90B1 CLASP1 PDHA1 DYNC2H1 SYNE1 RAD21L1 APOB RPS23 CFAP43 ECPAS THOC2 CIT BANF1 MAP3K4 NOP58 AP2B1 SYNE2 POP1 CDK5RAP2 MACF1 FERMT2 FBXO21 PCID2 WWC1 DYRK3 CCDC40 RAD21

1.53e-06145015429int:CIT
InteractionWWC1 interactions

TNIK TRIM25 WWC3 CIT ATM CPVL WWC1

7.79e-06941547int:WWC1
InteractionPTEN interactions

TDRD15 HSP90B1 TRIM25 CDC42BPA PDHA1 RPS23 THOC2 ARMC2 CIT PPL RYR3 FSIP2 PARP1 NOP58 AP2B1 SCARB2 POP1 ATM FSBP UTRN RAD21

8.34e-0692915421int:PTEN
InteractionGSK3B interactions

TNIK HSP90B1 GAPVD1 TRIM25 CLASP1 AIMP1 SGK1 BCCIP RICTOR MAP3K4 SGK3 PARP1 PPP2R5D AP2B1 RNPEP FBXO7 MACF1 FERMT2 UTRN WWC1

1.06e-0586815420int:GSK3B
InteractionLRRC31 interactions

DOCK1 TRIM25 CDC42BPA RICTOR ECPAS CIT PARP1 NCAPD2 TTC17

2.90e-052051549int:LRRC31
InteractionTNIK interactions

TNIK CLASP1 SYNE1 CIT PPP2R5D AP2B1 SYNE2 MACF1 PRKCG MGA CPVL WWC1

3.77e-0538115412int:TNIK
InteractionSEPTIN9 interactions

CDC42BPA PDHA1 RICTOR CIT INPP4B PARP1 PPP2R5D FERMT2 CPVL ACAP3

3.81e-0526515410int:SEPTIN9
InteractionIK interactions

THOC1 PDHA1 RICTOR EZH1 THOC2 CIT PPP2R5E CEP70 ATM

4.21e-052151549int:IK
InteractionGJA1 interactions

PDXDC1 TNIK ROCK2 MYH6 CDC42BPA TBC1D2B RICTOR APOB PARP1 GCC2 SYNE2 MACF1 PRKCG FERMT2 UTRN

4.21e-0558315415int:GJA1
InteractionTHOC3 interactions

THOC1 TRIM25 API5 THOC2 CIT UTRN

5.48e-05871546int:THOC3
InteractionPPP2R5C interactions

TRIM25 API5 PPP2R5C PPP2R5D PPP2R5E ATM

5.48e-05871546int:PPP2R5C
InteractionGSK3A interactions

TNIK GAPVD1 TRIM25 CLASP1 SGK1 BCCIP RICTOR SGK3 PARP1 MACF1 PRKCG UTRN WWC1

5.94e-0546415413int:GSK3A
InteractionTERF1 interactions

HSP90B1 DNAAF11 THOC2 RYR2 TRIM16 SYNE2 FES CFAP58 ATM FBXO21 UTRN

7.56e-0534715411int:TERF1
InteractionC9orf78 interactions

PDXDC1 TRIM25 IQGAP2 ECPAS PARP1 PPP2R5C PPP2R5D PPP2R5E AP2B1 RNPEP SCARB2 NCAPD2 CPVL PCID2 RAD21

8.42e-0562015415int:C9orf78
InteractionMYL2 interactions

ROCK2 MYH6 CDC42BPA ASPM

8.79e-05311544int:MYL2
Cytoband1q41-q42

PARP1 TLR5

1.15e-04515721q41-q42
Cytoband5q22.3

PGGT1B CCDC112

3.21e-04815725q22.3
Cytoband14q23.1

CCDC175 LRRC9 PPP2R5E

5.70e-0447157314q23.1
GeneFamilyWD repeat domain containing|Protein phosphatase 2 regulatory subunits

PPP2R5C PPP2R5D PPP2R5E

5.92e-0515943696
GeneFamilyRyanodine receptors|Protein phosphatase 1 regulatory subunits

RYR2 RYR3

8.00e-053942287
GeneFamilyDyneins, axonemal

DNAH3 DNAH17 DNAH11

8.78e-0517943536
GeneFamilySpectrin repeat containing nuclear envelope family

SYNE1 SYNE2

1.59e-0449421252
GeneFamilyTHO complex

THOC1 THOC2

5.52e-047942770
GeneFamilyEF-hand domain containing|Plakins

PPL MACF1

7.34e-048942939
GeneFamilyCyclins|F-boxes other

FBXO25 FBXO7 FBXO21

1.09e-0339943560
GeneFamilyVPS9 domain containing

GAPVD1 ALS2

1.17e-0310942928
CoexpressionHAMAI_APOPTOSIS_VIA_TRAIL_UP

HSP90B1 TUT4 CDC42BPA IQGAP2 AIMP1 VPS13C BCCIP CCDC112 FBXO25 GCC2 SYNE2 CEP70 ASPM FER CDK5RAP2 ATM DNAJC3 RAD21

8.83e-0865615718M18979
CoexpressionTRAVAGLINI_LUNG_CILIATED_CELL

DNAH3 IQGAP2 DYNC2H1 DNAJC16 IFT172 SYNE1 DNAAF11 CFAP43 ARMC2 BANF1 FOCAD RNPEP GCC2 SYNE2 CFAP58 CC2D2A VWA3B CFAP57 HYDIN WWC1 CCDC40 DNAH11

6.49e-07109315722M41649
CoexpressionGSE27241_WT_VS_RORGT_KO_TH17_POLARIZED_CD4_TCELL_TREATED_WITH_DIGOXIN_UP

TUT4 IQGAP2 VPS13C NCAPD2 MACF1 VWA3B ATM UTRN RAD21

1.47e-061801579M8239
CoexpressionZHENG_CORD_BLOOD_C3_MEGAKARYOCYTE_ERYTHROID_PROGENITOR

CDC42BPA BCCIP RYR3 CCDC112 REXO2 PARP1 FBXO7

2.43e-061001577M39212
CoexpressionDESCARTES_FETAL_LUNG_CILIATED_EPITHELIAL_CELLS

DNAH3 FMO3 CCDC160 DNAAF11 CFAP43 ARMC2 LRRC9 CFAP58 CC2D2A VWA3B CFAP57 HYDIN CCDC40 DNAH11

4.96e-0654015714M40241
CoexpressionLAKE_ADULT_KIDNEY_C2_PODOCYTES

IQGAP2 DYNC2H1 LRRC2 RYR3 MACF1 ANKRD36 CMAHP UTRN LARGE1

5.62e-062121579M39221
CoexpressionDESCARTES_MAIN_FETAL_CILIATED_EPITHELIAL_CELLS

DNAH3 DYNC2H1 IFT172 TOGARAM1 CCDC160 DNAAF11 CFAP43 ARMC2 LRRC9 CFAP58 CC2D2A VWA3B HYDIN CCDC40 DNAH11

1.49e-0567815715M40124
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

DOCK1 ROCK2 GAPVD1 TUT4 CDC42BPA CLASP1 TOGARAM1 THOC2 MAP3K4 PPP2R5C PPP2R5E GCC2 SYNE2 MACF1 STK39 FERMT2 WWC1

1.59e-0585615717M4500
CoexpressionDESCARTES_FETAL_STOMACH_CILIATED_EPITHELIAL_CELLS

DNAH3 DNAAF11 CFAP43 CFAP58 CC2D2A VWA3B CFAP57 HYDIN CCDC40 DNAH11

2.27e-0531715710M40298
CoexpressionGSE6875_WT_VS_FOXP3_KO_TREG_DN

SYNE1 CFAP43 NAALADL2 ADAM28 PPL GLB1 NCAPD2 ACAP3

2.79e-051991578M6804
CoexpressionGSE41867_NAIVE_VS_DAY6_LCMV_ARMSTRONG_EFFECTOR_CD8_TCELL_UP

LRRC2 MIDEAS INPP4B PARP1 GLB1 SYNE2 MGA WWC1

2.89e-052001578M9495
CoexpressionGSE45881_CXCR6HI_VS_CXCR1LO_COLONIC_LAMINA_PROPRIA_UP

PDXDC1 TNIK THOC2 MAP3K4 MACF1 ANKRD36 CMAHP CPVL

2.89e-052001578M9889
CoexpressionGSE7568_IL4_VS_IL4_AND_TGFB_TREATED_MACROPHAGE_24H_UP

HEXB TNIK EZH1 FBXO25 PPP2R5E SCARB2 NCAPD2

6.87e-051671577M365
CoexpressionAtlasDevelopingKidney_e15.5_Medullary collecting duct_emap-28063_k-means-cluster#4_top-relative-expression-ranked_1000

DOCK1 TUT4 IQGAP2 INO80 ECPAS CCDC141 CUL5 UTRN DNAJC3 WWC1

1.93e-0526115210gudmap_developingKidney_e15.5_Medullary collecting duct_1000_k4
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH3 FAM184A DYNC2H1 SYNE1 CCDC175 CFAP43 ARMC2 LRRC9 SYNE2 VWA3B CFAP57 HYDIN CCDC40 DNAH11

1.20e-141971571474a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCellPSB-critical-LOC-Epithelial-Ciliated|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNAH3 DYNC2H1 SYNE1 DNAAF11 CFAP43 ARMC2 CFAP58 CC2D2A VWA3B CFAP57 HYDIN CCDC40 DNAH11

2.85e-13197157136865f4831eb23794fb88a8649d48d497bbae3f44
ToppCellmoderate-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DNAH3 DYNC2H1 SYNE1 DNAAF11 CFAP43 ARMC2 CC2D2A VWA3B CFAP57 HYDIN CCDC40 DNAH11

5.49e-12195157123486eae5fdb062a75a907b896c9d7b396d2aa195
ToppCellsevere-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

TNIK SYNE1 ANKRD36C INPP4B MAP3K4 PPP2R5C GCC2 SYNE2 MACF1 ANKRD36 ATM UTRN

6.20e-121971571257ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCellNS-moderate-d_0-4-Epithelial-Ciliated|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNAH3 DYNC2H1 SYNE1 DNAAF11 CFAP43 ARMC2 CC2D2A VWA3B CFAP57 HYDIN CCDC40 DNAH11

6.20e-121971571271fea4aa6ce96c7693fa94792d08770622873850
ToppCell10x5'-bone_marrow-Lymphocytic_T_CD4-T_CD4/CD8|bone_marrow / Manually curated celltypes from each tissue

PDXDC1 FAM184A RICTOR ANKRD36C INPP4B PPP2R5C SYNE2 MACF1 ANKRD36 ATM SMG6

9.87e-12156157111545169694f686d28648a68b552c2ae606599d66
ToppCell5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH3 DYNC2H1 CCDC175 DNAAF11 CFAP43 LRRC9 VWA3B CFAP57 HYDIN CCDC40 DNAH11

2.36e-1116915711fba841664939c771881ba97f14ef1df6635c04ff
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8|lymph-node_spleen / Manually curated celltypes from each tissue

TUT4 SYNE1 APOB ANKRD36C INPP4B PPP2R5C SYNE2 MACF1 ANKRD36 ATM UTRN

2.68e-11171157112e9a20f8980b78325c52065a9c14ab3656267c05
ToppCellNS-control-d_0-4-Epithelial-Ciliated|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNAH3 DYNC2H1 SYNE1 DNAAF11 CFAP43 CC2D2A VWA3B CFAP57 HYDIN CCDC40 DNAH11

1.16e-1019615711d46ab80554dd3c1cc81e1938ea2acfd5e85c6d2a
ToppCellCOVID_non-vent-Lymphocytic|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

TNIK TUT4 SYNE1 ANKRD36C INPP4B PPP2R5C GCC2 SYNE2 MACF1 ANKRD36 ATM

1.23e-1019715711c672915f8c8c1e948d251f6eaf9f84a5600c1193
ToppCellcontrol-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DNAH3 DYNC2H1 SYNE1 DNAAF11 CFAP43 CC2D2A VWA3B CFAP57 HYDIN CCDC40 DNAH11

1.23e-1019715711e453d085182364ca347cbcc9dc995c62c3353016
ToppCellcontrol-Epithelial-Ciliated|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DNAH3 DYNC2H1 SYNE1 DNAAF11 CFAP43 CC2D2A VWA3B CFAP57 HYDIN CCDC40 DNAH11

1.23e-1019715711d4e963c1f82996371bf3d63578ee9fce8e00c5a8
ToppCellcritical-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DNAH3 DYNC2H1 SYNE1 DNAAF11 CFAP43 CC2D2A VWA3B CFAP57 HYDIN CCDC40 DNAH11

1.30e-1019815711ee2c8385c0bf4ea9f5c9517b52cf131af3fbdd40
ToppCellmild-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

TNIK SYNE1 RICTOR ANKRD36C PPP2R5C SYNE2 MACF1 ANKRD36 ATM UTRN SMG6

1.37e-1019915711f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCell3'-Distal_airway-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH3 DYNC2H1 CFAP43 ARMC2 MYO3A VWA3B CFAP57 HYDIN CCDC40 DNAH11

6.25e-1017315710c3762655caa79ac4879876f470d32578a3c93b01
ToppCellNS-moderate-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNAH3 DYNC2H1 CFAP43 CFAP58 CC2D2A VWA3B CFAP57 HYDIN CCDC40 DNAH11

1.20e-09185157105e689c2fb36ce3ac2adc8d15f67107f21cf68868
ToppCellNS-critical-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNAH3 DYNC2H1 DNAAF11 CFAP43 CC2D2A VWA3B CFAP57 HYDIN CCDC40 DNAH11

1.27e-091861571076033438426d8f9c72cd6691a7baf92104c9f03d
ToppCellNS-moderate-d_07-13-Epithelial-Ciliated|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNAH3 DNAAF11 CFAP43 CFAP58 CC2D2A VWA3B CFAP57 HYDIN CCDC40 DNAH11

1.27e-091861571085787ff207f109ec7e3c0f729ba9bda739c2fdc9
ToppCellNasal_Brush-Epithelial-Ciliated_2|Nasal_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

DNAH3 DYNC2H1 SYNE1 DNAAF11 CFAP43 CC2D2A VWA3B CFAP57 HYDIN DNAH11

1.56e-09190157109ce7df056bfb24d70db4c3c4a2c57d89115de877
ToppCellNasal_Brush-Epithelial-Ciliated_2|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

DNAH3 DYNC2H1 SYNE1 DNAAF11 CFAP43 CC2D2A VWA3B CFAP57 HYDIN DNAH11

1.56e-0919015710833481ace2800354712e2ce709d5cdfd0aed3d42
ToppCellCiliated-cil-3|World / Class top

DNAH3 DYNC2H1 IFT172 SYNE1 CFAP43 CFAP57 HYDIN DYRK3 CCDC40 DNAH11

1.72e-09192157104989ebb8812b8af1870599acd932849122c05a29
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.3|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH3 DYNC2H1 DNAAF11 CFAP43 CFAP58 CC2D2A CFAP57 HYDIN CCDC40 DNAH11

1.81e-0919315710e1b76102f812c433195d1e8811fdd3293a7bc22e
ToppCellNS-moderate-d_0-4|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNAH3 FAM184A DYNC2H1 CFAP43 ARMC2 VWA3B CFAP57 HYDIN CCDC40 DNAH11

1.81e-0919315710ea345d34440b25f65358a53dc72831998d1c3620
ToppCellIPF-Epithelial-Ciliated|Epithelial / Disease state, Lineage and Cell class

DNAH3 DYNC2H1 SYNE1 DNAAF11 CFAP43 ARMC2 VWA3B HYDIN CCDC40 DNAH11

1.81e-0919315710ad58f5080e0ba65c845056ea6b79037b636e9c64
ToppCellsevere-low-quality_cells|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

TNIK SYNE1 ANKRD36C INPP4B MAP3K4 SYNE2 MACF1 ANKRD36 ATM UTRN

1.81e-09193157109337bc93e3904c7fc7c93c328518bcd6453b1e8c
ToppCellASK440-Epithelial-Ciliated|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq

DNAH3 DYNC2H1 DNAAF11 CFAP43 CC2D2A VWA3B CFAP57 HYDIN CCDC40 DNAH11

1.90e-0919415710c84a7fa94fb06e08aae04db56c8c313b0afde1d7
ToppCellNS-critical-d_07-13-Epithelial-Ciliated|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNAH3 DYNC2H1 DNAAF11 CFAP43 CC2D2A VWA3B CFAP57 HYDIN CCDC40 DNAH11

1.90e-09194157101ae8a10e508e672e6677f0e3c986ac30d05adeb3
ToppCellmoderate-Epithelial-Ciliated|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DNAH3 DYNC2H1 DNAAF11 CFAP43 CC2D2A VWA3B CFAP57 HYDIN CCDC40 DNAH11

2.00e-0919515710e80f5cdf0b18066b3e6c2f5452e58f101c67932c
ToppCellBL-critical-LOC-Epithelial-Ciliated|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNAH3 DYNC2H1 IFT172 CFAP43 CC2D2A VWA3B CFAP57 HYDIN CCDC40 DNAH11

2.00e-091951571007a6bcef6af93ed87df455dee624037cb75e011a
ToppCellcritical-Epithelial-Ciliated|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DNAH3 DYNC2H1 DNAAF11 CFAP43 CC2D2A VWA3B CFAP57 HYDIN CCDC40 DNAH11

2.10e-091961571027b855c6e1ae44f16db998cf0e81bd686b9cee7e
ToppCellCOPD-Multiplet-Multiplet|COPD / Disease state, Lineage and Cell class

DNAH3 SYNE1 CFAP43 SYNE2 ASPM MACF1 CMAHP HYDIN WWC1 DNAH11

2.10e-0919615710af4cdc61830685a888a1209826c23bcf54a43084
ToppCellCOPD-Multiplet|COPD / Disease state, Lineage and Cell class

DNAH3 SYNE1 CFAP43 SYNE2 ASPM MACF1 CMAHP HYDIN WWC1 DNAH11

2.10e-09196157106d02d494196e3f857d53eea46d9419690d43beca
ToppCell10x_3'_v3-blood_(10x_3'_v3)-lymphocytic-T_lymphocytic-type_I_NK_T_cell|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

TNIK CLASP1 SYNE1 ANKRD36C PPP2R5C SYNE2 MACF1 STK39 ATM UTRN

2.32e-091981571058d805e827299292750b09c6283fdbe406b75f79
ToppCellBronchus_Control_(B.)-Epithelial-TX-Ciliated|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

DNAH3 DYNC2H1 IFT172 SYNE1 DNAAF11 CFAP43 CFAP57 HYDIN CCDC40 DNAH11

2.55e-09200157106a2ccc71a0cbe04a542c379b28b5006de53981c3
ToppCellAdult-Epithelial-ciliated_cell-D175|Adult / Lineage, Cell type, age group and donor

DNAH3 CCDC175 CFAP43 CFAP58 VWA3B CFAP57 HYDIN CCDC40 DNAH11

2.07e-08185157930f4980dee6cd5959655f8d74049f3bfb5312611
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TNIK SYNE1 PPL CPVL UTRN HYDIN WWC1 DNAH11 LARGE1

2.38e-08188157963a4b25a0a6e05f80f1a6dd91b817f3cf49e6b68
ToppCellCOPD-Epithelial-Ciliated|Epithelial / Disease state, Lineage and Cell class

DNAH3 DYNC2H1 DNAAF11 CFAP43 ARMC2 VWA3B HYDIN CCDC40 DNAH11

2.49e-0818915793e77883db34722b9ce0a03ea74caefc92dc7feff
ToppCellASK428-Epithelial-Ciliated|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq

DNAH3 FMO3 DNAAF11 CFAP43 CFAP58 VWA3B CFAP57 HYDIN DNAH11

2.73e-0819115790c4b926a28bc94f3cf4d68a911c0a189f6ff505e
ToppCell3'_v3-blood-Lymphocytic_T_CD4-T_CD4/CD8|blood / Manually curated celltypes from each tissue

SYNE1 ANKRD36C PPP2R5C SYNE2 MACF1 ANKRD36 CFAP57 UTRN

2.80e-081351578ae2d3a42e567b5bade304c0caa497eb725be3565
ToppCell10x5'-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8|lymph-node_spleen / Manually curated celltypes from each tissue

TNIK FAM184A ANKRD36C INPP4B PPP2R5C SYNE2 MACF1 ANKRD36 ATM

2.86e-08192157947646d7e4990be85072987f92bf18d52f8da752e
ToppCellControl-Epithelial-Ciliated|Epithelial / Disease state, Lineage and Cell class

DNAH3 DYNC2H1 DNAAF11 CFAP43 ARMC2 VWA3B HYDIN CCDC40 DNAH11

2.99e-0819315790e37d454f3735edd936ee9a5f5f516ac3aad400e
ToppCellASK440-Epithelial-Ciliated|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq

DNAH3 DYNC2H1 DNAAF11 CFAP43 VWA3B CFAP57 HYDIN CCDC40 DNAH11

2.99e-081931579a0baa8be6f590b2031fede22be588715ae458e93
ToppCellASK452-Epithelial-Ciliated|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq

DNAH3 DNAAF11 CFAP43 CFAP58 CC2D2A VWA3B CFAP57 HYDIN DNAH11

3.12e-0819415795aeb44657ab6f61b1abf98af28d3397d8e44c1aa
ToppCellIPF-Multiplet-Multiplet|IPF / Disease state, Lineage and Cell class

DNAH3 DYNC2H1 SYNE1 CFAP43 SYNE2 VWA3B HYDIN WWC1 DNAH11

3.26e-081951579fce0c29574bb7aab181b9c00feb42681e285d1f2
ToppCellCOVID_non-vent-Lymphocytic-T_cell|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

TNIK ANKRD36C INPP4B PPP2R5C GCC2 SYNE2 MACF1 ANKRD36 ATM

3.26e-0819515794bdedd924564a260841a9153604026b57487c83d
ToppCellIPF-Multiplet|IPF / Disease state, Lineage and Cell class

DNAH3 DYNC2H1 SYNE1 CFAP43 SYNE2 VWA3B HYDIN WWC1 DNAH11

3.26e-081951579eacc0449ae6f3ad8002268cd061467684c6fb9a7
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH3 DYNC2H1 IFT172 SYNE1 CFAP43 CC2D2A VWA3B HYDIN DNAH11

3.56e-08197157991637bdeab85024b5a02d1066f76cb803a2d6420
ToppCellsystemic_lupus_erythematosus-flare|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

TUT4 VPS13C SYNE1 RICTOR GCC2 SYNE2 MACF1 ANKRD36 ATM

3.72e-0819815794c93ee921d56132d80832d8e94563f32ccf13bbc
ToppCell10x_3'_v3-blood_(10x_3'_v3)-lymphocytic-T_lymphocytic-CD8-positive,_alpha-beta_cytokine_secreting_effector_T_cell|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

TNIK CLASP1 SYNE1 ANKRD36C PPP2R5C SYNE2 MACF1 ATM UTRN

3.72e-08198157934c564ece9a2b94dcf646e3c95b5be9c5ecfaafe
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TNIK TUT4 SYNE1 ANKRD36C INPP4B NOP58 GCC2 SYNE2 ATM

3.72e-081981579a3bd099ef0e606c2da690a6fcf6f79e9360c9c9f
ToppCell(09)_Interm._secr.>cil.-(2)_GFP_FOXI1|(09)_Interm._secr.>cil. / shred by cell type by condition

CDC42BPA IQGAP2 VPS13C THOC2 REXO2 PPP2R5E GCC2 SYNE2 DNAJC3

3.89e-081991579fc680f85ebd3bab4c72876a19a461b0afb5f51ce
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_ciliated-Ciliated|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DNAH3 CCDC175 DNAAF11 CFAP43 CFAP58 VWA3B CFAP57 HYDIN CCDC40

4.06e-082001579926a7ea94b5908aebf103893ea83ce9d25285b65
ToppCellBiopsy_IPF-Epithelial-Ciliated|Biopsy_IPF / Sample group, Lineage and Cell type

DNAH3 DYNC2H1 IFT172 CFAP43 CC2D2A VWA3B CFAP57 HYDIN DNAH11

4.06e-082001579bb8c99156e547a8eb6599b6b6bc3c66bf77af7f8
ToppCell(09)_Interm._secr.>cil.|World / shred by cell type by condition

DYNC2H1 SYNE1 DNAAF11 CFAP43 CC2D2A VWA3B CFAP57 HYDIN CCDC40

4.06e-0820015793305e14dba12e94da42f0414fdc7a2c8caf0a183
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_ciliated|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DNAH3 CCDC175 DNAAF11 CFAP43 CFAP58 VWA3B CFAP57 HYDIN CCDC40

4.06e-08200157906ce6e03498ba38ef6a06eaf2731e3b2eeda59eb
ToppCellLPS_only-Epithelial_airway-Ciliated_cells-Ciliated|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH3 CCDC160 DNAAF11 CFAP43 LRRC9 CFAP58 HYDIN DNAH11

7.79e-0815415789ca71d440c4f87781e6525b8141e7d8d470b6a8e
ToppCellLPS_only-Epithelial_airway-Ciliated_cells|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH3 CCDC160 DNAAF11 CFAP43 LRRC9 CFAP58 HYDIN DNAH11

7.79e-08154157858072ce422d09f2de602580325eaac6c4ec6c136
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH3 DYNC2H1 DNAAF11 CFAP43 ARMC2 CFAP57 HYDIN DNAH11

1.59e-07169157814aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCellCiliated_cells-A-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

DNAH3 FMO3 CCDC160 CFAP43 CFAP58 VWA3B HYDIN DNAH11

2.37e-071781578255473ee6df8a13079fb3bb61038162a40cb4c2c
ToppCell3'_v3-bone_marrow-Lymphocytic_T_CD4-T_CD4/CD8|bone_marrow / Manually curated celltypes from each tissue

SYNE1 APOB ANKRD36C SYNE2 MACF1 ANKRD36 ATM

2.49e-07121157719333a660800b583fa27b495c1f7828e6636a257
ToppCellAdult-Epithelial-ciliated_cell-D122|Adult / Lineage, Cell type, age group and donor

DNAH3 CFAP43 CFAP58 VWA3B CFAP57 HYDIN CCDC40 DNAH11

2.81e-0718215787ded554a4b441e6496db673ba206c0d76ccad7d9
ToppCellControl-Epithelial_cells-Airway_ciliated|Control / group, cell type (main and fine annotations)

DNAH3 DNAAF11 CFAP43 CFAP58 VWA3B CFAP57 HYDIN DNAH11

2.81e-071821578fb725d10d9ed25dfc6d5bb69cfef78513f7d3e8f
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

TNIK FAM184A INPP4B PPP2R5C GCC2 SYNE2 ANKRD36 ATM

2.93e-071831578f2ef110bf29b1a8276ef216238363e542db262c1
ToppCellP15-Epithelial-airway_epithelial_cell-club_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

DNAH3 MYH6 DNAAF11 CFAP58 CFAP57 HYDIN DYRK3 CCDC40

3.45e-071871578a70aaae32426e9ddb1cbfbd0e0db24ccc96b9f40
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

VPS13C RICTOR ANKRD36C SYNE2 MACF1 ANKRD36 UTRN SMG6

3.60e-071881578ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCellEpithelial-ciliated_cell|World / Lineage, Cell type, age group and donor

DNAH3 CFAP43 CFAP58 VWA3B CFAP57 HYDIN CCDC40 DNAH11

3.60e-07188157861a459f3fe57e5728efc72637ff2edc2d343492b
ToppCellP15-Epithelial-airway_epithelial_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

DNAH3 MYH6 DNAAF11 CFAP58 CFAP57 HYDIN DYRK3 CCDC40

3.60e-071881578e3e71c0f2e374330620cb4d27638953ffa9f5298
ToppCellPND10-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DNAH3 DNAAF11 CFAP43 CFAP58 CFAP57 HYDIN CCDC40 DNAH11

3.74e-07189157802c6128a9ab5818e0881dcadafdad5f08b9a67cf
ToppCellChildren_(3_yrs)-Epithelial-ciliated_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

DNAH3 CFAP43 CFAP58 VWA3B CFAP57 HYDIN CCDC40 DNAH11

3.74e-07189157868a3cf7763d6f9b95d6d6524eff7a16042703f1d
ToppCellPND10-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DNAH3 DNAAF11 CFAP43 CFAP58 CFAP57 HYDIN CCDC40 DNAH11

3.74e-071891578164ea92ff6a1aa2ead1c9b8f64f99a9d65437232
ToppCellPND10-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DNAH3 DNAAF11 CFAP43 CFAP58 CFAP57 HYDIN CCDC40 DNAH11

3.74e-071891578a85099bd598a27ee64ee0664d051d89fa8d62fc9
ToppCellAdult-Epithelial-ciliated_cell|Adult / Lineage, Cell type, age group and donor

DNAH3 CFAP43 CFAP58 VWA3B CFAP57 HYDIN CCDC40 DNAH11

3.74e-071891578b679920f0993e917dd86da082113bfbd85ea1ca5
ToppCellCOVID-19-lung-Ciliated|lung / Disease (COVID-19 only), tissue and cell type

DNAH3 CCDC175 CFAP43 CFAP58 VWA3B CFAP57 HYDIN DNAH11

3.74e-07189157827329c4661aebabd19fac7fe5dca263fe99d76f3
ToppCellLV-06._Ventricular_Cardiomyocyte_II|World / Chamber and Cluster_Paper

TNIK LRRC2 CCDC141 INPP4B RYR2 SPHKAP CPVL LARGE1

3.90e-071901578de5ef606a002f85c2e0e3a36c1f259d0b85a76ff
ToppCellnucseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

DNAH3 DNAAF11 CFAP43 CFAP58 VWA3B CFAP57 HYDIN DNAH11

4.06e-071911578e417bf491f8b8d7838a61f7f4f6b1740ba97aa3f
ToppCellnucseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

DNAH3 DNAAF11 CFAP43 CFAP58 VWA3B CFAP57 HYDIN DNAH11

4.06e-0719115789d31c8424d35bdc0c27188b68bfd0f731af3600b
ToppCellfacs-Lung-3m-Epithelial-airway_epithelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DNAAF11 CFAP43 ADAM28 CFAP58 CFAP57 HYDIN CCDC40 DNAH11

4.06e-0719115786a8fc9dc1a4c7115862e8f20204fa2f95e50e22f
ToppCellnucseq-Epithelial-Epithelial_Airway|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

DNAH3 DYNC2H1 DNAAF11 CFAP43 VWA3B CFAP57 HYDIN DNAH11

4.06e-0719115781c528f72c9ef3ef3a850b05e4a9715190832270c
ToppCellBronchial_Biopsy-Epithelial-Ciliated_1|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X

DNAH3 SYNE1 DNAAF11 CFAP43 VWA3B CFAP57 HYDIN DNAH11

4.22e-071921578be592e661367affced9ebe80849b466e6adb3a34
ToppCellLV-04._Ventricular_Cardiomyocyte_I|LV / Chamber and Cluster_Paper

TNIK MYH6 LRRC2 CCDC141 INPP4B RYR2 SPHKAP LARGE1

4.22e-071921578ad19e2c1d36a0566c9b12ced10db78f4781c8ea6
ToppCell15-Trachea-Epithelial-Intermediate_ciliated|Trachea / Age, Tissue, Lineage and Cell class

KRT4 IFT172 CFAP43 ARMC2 PPL VWA3B HYDIN DNAH11

4.22e-0719215789cbe961a800c981cdc742a47ed18e9c8eb6430bd
ToppCellASK452-Epithelial-Ciliated|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq

DNAAF11 CFAP43 CFAP58 CC2D2A VWA3B CFAP57 HYDIN DNAH11

4.39e-071931578c0d10075862ac878aa05fc49c8b73e470783bf16
ToppCellBronchial_Biopsy-Epithelial-Ciliated_1|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

DNAH3 SYNE1 DNAAF11 CFAP43 VWA3B CFAP57 HYDIN DNAH11

4.39e-0719315780b62a6ddd7c42efd9f39781971d1438501e1fa8d
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.3|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FAM184A DYNC2H1 SYNE1 CFAP43 VWA3B HYDIN WWC1 DNAH11

4.39e-071931578bdb7401dd9059032f930f2b575f2ef8e504b6594
ToppCellhuman_hepatoblastoma|World / Sample and Cell Type and Tumor Cluster (all cells)

ROCK2 TUT4 RICTOR RPS23 GCC2 FER UTRN RAD21

4.39e-071931578e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCellBronchial_Brush-Epithelial-Ciliated_1|Bronchial_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

DYNC2H1 SYNE1 DNAAF11 CFAP43 CC2D2A VWA3B HYDIN DNAH11

4.56e-071941578b4ce60c06568123008b1081d644733cb91c28f51
ToppCellBronchial_Brush-Epithelial-Ciliated_1|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

DYNC2H1 SYNE1 DNAAF11 CFAP43 CC2D2A VWA3B HYDIN DNAH11

4.56e-0719415787a7ddccfe72a4a0dc4d1a5c809988f0069f9f1a3
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH3 DYNC2H1 SYNE1 CFAP43 CFAP57 HYDIN CCDC40 DNAH11

4.56e-0719415784a2c127c90d1fefe604fcb9e796577d21b489dd6
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DYNC2H1 IFT172 DNAAF11 CFAP43 VWA3B CFAP57 HYDIN DNAH11

4.56e-071941578a46238514bca920c3e3713d23c18ba24a09e2a29
ToppCellCOVID-19-Heart-CM_1|Heart / Disease (COVID-19 only), tissue and cell type

TNIK LRRC2 CCDC141 INPP4B RYR2 SPHKAP CPVL LARGE1

4.75e-071951578f1ef50331eda8f1239dba6ea970df4eaccf032f1
ToppCellIPF-Multiplet-Multiplet|World / Disease state, Lineage and Cell class

DNAH3 DYNC2H1 CFAP43 SYNE2 VWA3B HYDIN WWC1 DNAH11

4.75e-07195157821dbdc803c6947024dc2416e9e21c2ef0af9bc31
ToppCellNS-critical-LOC-Epithelial-Ciliated|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNAH3 DYNC2H1 CFAP43 CC2D2A VWA3B CFAP57 HYDIN DNAH11

4.75e-07195157834e37cff4849696ca4ba5dd8fd2cf98fed8bc912
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TNIK TUT4 ANKRD36C NOP58 GCC2 SYNE2 ANKRD36 FBXO21

4.75e-071951578ed5f772c82d4dfd1c8735224446ec9feae3fb8c2
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TNIK SYNE1 ANKRD36C INPP4B PPP2R5C GCC2 SYNE2 ATM

4.93e-071961578c4e7133c609bcbc48c4947ea0aa1a7d9d7251b04
ToppCellSmart-seq2-tissue-resident_(Smart-seq2)-lymphocytic-T_lymphocytic-T_cell|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

RICTOR RPS23 INPP4B PPP2R5C GCC2 MTRFR SYNE2 ANKRD36

4.93e-0719615784a880a5d2c7047c050c7d6dd62186f35dc5c01f7
ToppCell(05)_Ciliated|World / shred by cell type and Timepoint

IFT172 SYNE1 DNAAF11 CFAP43 CFAP58 CFAP57 HYDIN CCDC40

5.13e-071971578fee3cd16af8eea697cd64e8f64af505aaa2ac4b0
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH3 DYNC2H1 IFT172 SYNE1 CFAP43 VWA3B HYDIN DNAH11

5.13e-07197157822c87dd15dc57bd0aa98a204c9fc9b3b9b573b45
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH3 DYNC2H1 IFT172 SYNE1 CFAP43 VWA3B HYDIN DNAH11

5.13e-0719715783bbf068d2ad8196fbc85d3f311a7c54c9aece856
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH3 DYNC2H1 IFT172 SYNE1 CFAP43 VWA3B HYDIN DNAH11

5.13e-07197157887db09f341e2b20eb6e1c3e917cb5c960387b3e9
ToppCellCOVID_vent-Lymphocytic-T_cell|COVID_vent / Disease condition, Lineage, Cell class and subclass

SYNE1 RPS23 INPP4B PPP2R5C GCC2 SYNE2 MACF1 ATM

5.13e-071971578ad702e440a74d54cfdcb8bb1c66bd8e0e71ab04e
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

SYNE1 GCC2 SYNE2 MACF1 ATM UTRN

4.18e-0649956GAVISH_3CA_METAPROGRAM_CD8_T_CELLS_CHROMATIN
Drugpotassium bromide

HSP90B1 SYNE1 APOB APOL1 REXO2 GLB1

7.29e-07461576CID000253877
Diseasetissue plasminogen activator measurement, coronary artery disease

TDRD15 DYNC2H1 APOB MAP3K4 SMG6

3.47e-05711535EFO_0001645, EFO_0004791
DiseasePrimary ciliary dyskinesia

DNAAF11 HYDIN CCDC40 DNAH11

3.60e-05361534cv:C0008780
Diseasecholesterol:total lipids ratio, intermediate density lipoprotein measurement

PDXDC1 TDRD15 APOB SYNE2 MACF1 PLCB3

4.14e-051211536EFO_0008595, EFO_0020943
Diseasecongenital myopathy 1A (implicated_via_orthology)

RYR2 RYR3

7.99e-0531532DOID:3529 (implicated_via_orthology)
Diseasemalignant hyperthermia (implicated_via_orthology)

RYR2 RYR3

7.99e-0531532DOID:8545 (implicated_via_orthology)
DiseasePrimary Ciliary Dyskinesia

DNAAF11 HYDIN CCDC40 DNAH11

1.04e-04471534C4551720
Diseasecholesterol:total lipids ratio, low density lipoprotein cholesterol measurement

PDXDC1 TDRD15 APOB SYNE2 MACF1 PLCB3

1.09e-041441536EFO_0004611, EFO_0020943
Diseasephosphatidylcholine measurement

PDXDC1 TDRD15 IFT172 APOB GLB1 NRXN2 SYNE2 MACF1

1.24e-042841538EFO_0010226
Diseasetriglycerides:total lipids ratio, low density lipoprotein cholesterol measurement

PDXDC1 TDRD15 APOB SYNE2 MACF1 PLCB3

1.36e-041501536EFO_0004611, EFO_0020947
DiseaseAutosomal dominant Emery-Dreifuss muscular dystrophy

SYNE1 SYNE2

1.59e-0441532cv:CN293514
Diseasetriglyceride measurement, very low density lipoprotein cholesterol measurement

PDXDC1 TDRD15 APOB ARMC2 SYNE2 MACF1 PLCB3

1.76e-042241537EFO_0004530, EFO_0008317
DiseaseAutosomal Recessive Primary Microcephaly

CIT ASPM CDK5RAP2

1.96e-04221533C3711387
DiseasePrimary microcephaly

CIT ASPM CDK5RAP2

1.96e-04221533C0431350
Diseasevery low density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio

PDXDC1 TDRD15 APOB VPS37B MACF1 PLCB3 CMAHP

2.61e-042391537EFO_0008317, EFO_0020945
DiseaseAutosomal Recessive Emery-Dreifuss Muscular Dystrophy

SYNE1 SYNE2

2.64e-0451532C1450051
DiseaseAutosomal Dominant Emery-Dreifuss Muscular Dystrophy (disorder)

SYNE1 SYNE2

2.64e-0451532C0410190
Diseasecoronary artery disease, plasminogen activator inhibitor 1 measurement

TDRD15 DYNC2H1 APOB SMG6

3.26e-04631534EFO_0001645, EFO_0004792
Diseasecholesterol to total lipids in medium LDL percentage

PDXDC1 TDRD15 APOB

3.65e-04271533EFO_0022238
DiseaseEmery-Dreifuss muscular dystrophy

SYNE1 SYNE2

3.95e-0461532cv:C0410189
DiseaseVACTERL association (implicated_via_orthology)

DYNC2H1 IFT172

3.95e-0461532DOID:14679 (implicated_via_orthology)
DiseaseMuscular Dystrophy, Emery-Dreifuss

SYNE1 SYNE2

3.95e-0461532C0410189
Diseaseserum metabolite measurement

PDXDC1 TNIK TDRD15 LAMB4 FMO3 CDC42BPA DNAJC16 APOB CIT DNAH17 SYNE2 FER STK39 ARHGAP20

4.23e-0494515314EFO_0005653
Diseaseangina pectoris

DYNC2H1 APOB FES CMAHP SMG6

4.99e-041251535EFO_0003913
Diseasetriglycerides:total lipids ratio, intermediate density lipoprotein measurement

PDXDC1 APOB SYNE2 MACF1 PLCB3

5.37e-041271535EFO_0008595, EFO_0020947
DiseaseJoubert syndrome (implicated_via_orthology)

TOGARAM1 CC2D2A

5.51e-0471532DOID:0050777 (implicated_via_orthology)
Diseaseatrioventricular septal defect (implicated_via_orthology)

IFT172 DNAH11

5.51e-0471532DOID:0050651 (implicated_via_orthology)
DiseaseAngle Closure Glaucoma

CHAT FERMT2

5.51e-0471532C0017605
DiseaseX-Linked Emery-Dreifuss Muscular Dystrophy

SYNE1 SYNE2

5.51e-0471532C0751337
Diseasetotal blood protein measurement

DNAH3 TRIM25 IQGAP2 TBC1D2B PARP1 MACF1 LRRC8B HYDIN SMG6

5.85e-044491539EFO_0004536
Diseasemicrocephaly (implicated_via_orthology)

CIT ASPM CDK5RAP2

6.07e-04321533DOID:10907 (implicated_via_orthology)
Diseaselow density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio

PDXDC1 TDRD15 APOB SYNE2 MACF1 PLCB3

6.36e-042001536EFO_0004611, EFO_0020945
Diseaseesterified cholesterol measurement, intermediate density lipoprotein measurement

TDRD15 APOB

7.33e-0481532EFO_0008589, EFO_0008595
DiseaseChromosomal Instability

PPP2R5C PPP2R5E

7.33e-0481532C1257806
Diseasemicrocephaly (is_implicated_in)

ASPM CDK5RAP2

7.33e-0481532DOID:10907 (is_implicated_in)
DiseaseKartagener Syndrome

DNAAF11 HYDIN CCDC40

7.92e-04351533C0022521
DiseaseCiliary Dyskinesia, Primary, 1, With Or Without Situs Inversus

DNAAF11 HYDIN CCDC40

7.92e-04351533C4551906
DiseasePolynesian Bronchiectasis

DNAAF11 HYDIN CCDC40

7.92e-04351533C4317124
DiseaseConventional (Clear Cell) Renal Cell Carcinoma

PDXDC1 INPP4B MYO3A SYNE2 ATM

1.07e-031481535C0279702
Diseasevery low density lipoprotein cholesterol measurement, cholesterol:total lipids ratio

PDXDC1 TDRD15 APOB SYNE2 MACF1 PLCB3

1.09e-032221536EFO_0008317, EFO_0020943
Diseasecongestive heart failure (implicated_via_orthology)

RYR2 POSTN PARP1

1.26e-03411533DOID:6000 (implicated_via_orthology)
Diseasefibrinogen measurement, coronary artery disease

TDRD15 DYNC2H1 NOP58 TTC17 SMG6

1.28e-031541535EFO_0001645, EFO_0004623
Diseasenevus count, cutaneous melanoma

PIGU PARP1 SYNE2 ATM

1.31e-03911534EFO_0000389, EFO_0004632
DiseaseJeune thoracic dystrophy

DYNC2H1 IFT172

1.42e-03111532C0265275
DiseaseCognitive impairment

NAALADL2 RYR2

1.42e-03111532HP_0100543
DiseaseBMI-adjusted waist-hip ratio, sex interaction measurement

IQGAP2 PIGU FERMT2

1.45e-03431533EFO_0007788, EFO_0008343
Diseasetriglycerides in large LDL measurement

TDRD15 APOB SYNE2

1.45e-03431533EFO_0022319
DiseaseC-reactive protein measurement

TDRD15 IFT172 VPS13C RICTOR APOB THOC2 PIGU CIT PPL NOP58 SPHKAP MTRFR DNAH17 MACF1 DNAH11

1.56e-03120615315EFO_0004458
DiseaseEmery-Dreifuss muscular dystrophy (implicated_via_orthology)

SYNE1 SYNE2

1.70e-03121532DOID:11726 (implicated_via_orthology)
DiseasePrenatal Exposure Delayed Effects

ADORA1 ATM

1.70e-03121532C0033054
Diseaseresponse to angiotensin-converting enzyme inhibitor, Cough

CLASP1 DNAJC16 NAALADL2

1.76e-03461533EFO_0005325, HP_0012735
Diseasemean corpuscular hemoglobin concentration

CLASP1 IQGAP2 BCCIP EZH1 MIDEAS FOCAD NOP58 FBXO7 CC2D2A MACF1 PLCB3 CMAHP DYRK3 CCDC40

1.89e-03110515314EFO_0004528
DiseaseShort Rib-Polydactyly Syndrome

DYNC2H1 IFT172

2.01e-03131532C0036996
Diseasegallbladder cancer (is_implicated_in)

RICTOR APOB

2.01e-03131532DOID:3121 (is_implicated_in)
Diseasecholesteryl esters:total lipids ratio, intermediate density lipoprotein measurement

APOB SYNE2 MACF1 PLCB3

2.06e-031031534EFO_0008595, EFO_0020944
Diseasecholesteryl ester 20:3 measurement

PDXDC1 FAM184A APOB

2.11e-03491533EFO_0010347
DiseaseSaldino-Noonan Syndrome

DYNC2H1 IFT172

2.33e-03141532C0036069
DiseaseMajewski Syndrome

DYNC2H1 IFT172

2.33e-03141532C0024507
Diseaseesterified cholesterol measurement, low density lipoprotein cholesterol measurement

TDRD15 APOB

2.33e-03141532EFO_0004611, EFO_0008589
Diseasedisease recurrence, colon carcinoma

ARMC2 MAP3K4 MACF1

2.37e-03511533EFO_0004952, EFO_1001950
Diseasefree cholesterol to total lipids in small HDL percentage

PDXDC1 TDRD15 APOB

2.37e-03511533EFO_0022285
DiseaseIntellectual Disability

SYNE1 PIGU PARP1 PPP2R5D NRXN2 MACF1 PRKCG LARGE1

2.39e-034471538C3714756
Diseasevery low density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio

PDXDC1 TDRD15 APOB SYNE2 MACF1 PLCB3

2.62e-032641536EFO_0008317, EFO_0020944
DiseaseCiliopathies

DYNC2H1 CC2D2A CCDC40 DNAH11

2.62e-031101534C4277690
Diseasetriglycerides to total lipids in very large VLDL percentage

PDXDC1 TDRD15 APOB

2.65e-03531533EFO_0022340
Diseaseglucose-dependent insulinotropic peptide measurement

CCDC141 VPS37B ADAM28

2.65e-03531533EFO_0008464
Diseasecholesteryl esters to total lipids in very large VLDL percentage

PDXDC1 TDRD15 APOB

2.65e-03531533EFO_0022258
Diseaseforehead morphology measurement

CPVL SMG6

2.68e-03151532EFO_0007844
Diseaselow density lipoprotein triglyceride measurement

TDRD15 APOB

2.68e-03151532EFO_0009946
DiseaseAutosomal recessive primary microcephaly

ASPM CDK5RAP2

2.68e-03151532cv:C3711387
Diseaseresponse to statin, LDL cholesterol change measurement

TDRD15 APOB

2.68e-03151532EFO_0007804, GO_0036273
Diseasecoronary artery disease, factor VII measurement

TDRD15 DYNC2H1 APOB SMG6

2.71e-031111534EFO_0001645, EFO_0004619
Diseasecholesterol to total lipids in very large VLDL percentage

PDXDC1 TDRD15 APOB

2.79e-03541533EFO_0022244
Diseasefactor VIII measurement, coronary artery disease

TDRD15 DYNC2H1 APOB SMG6

2.89e-031131534EFO_0001645, EFO_0004630
Diseasecomplex trait

TDRD15 GAPVD1 IFT172 APOB CCDC141 MACF1

2.98e-032711536EFO_0010578
Diseaseprimary autosomal recessive microcephaly (is_implicated_in)

NCAPD2 ASPM

3.06e-03161532DOID:0070296 (is_implicated_in)
Diseasetriglycerides in LDL measurement

TDRD15 APOB SYNE2

3.10e-03561533EFO_0022320
Diseasecholesterol to total lipids in large LDL percentage

PDXDC1 TDRD15 APOB

3.10e-03561533EFO_0022235
Diseasefree cholesterol to total lipids in large HDL percentage

PDXDC1 TDRD15 APOB

3.10e-03561533EFO_0022279
Diseasecholesteryl esters to total lipids in large VLDL percentage

PDXDC1 TDRD15 APOB

3.10e-03561533EFO_0022250
Diseasecreatinine measurement, glomerular filtration rate

DNAJC16 INO80 PIGU PDILT

3.27e-031171534EFO_0004518, EFO_0005208
Diseasevon Willebrand factor measurement, coronary artery disease

TDRD15 DYNC2H1 APOB SMG6

3.37e-031181534EFO_0001645, EFO_0004629
Diseasecholesterol in IDL measurement

PDXDC1 TDRD15 APOB

3.42e-03581533EFO_0021899
Diseasecholesterol to total lipids in chylomicrons and extremely large VLDL percentage

TDRD15 APOB

3.45e-03171532EFO_0022232
Diseaseperinatal necrotizing enterocolitis (biomarker_via_orthology)

PARP1 TLR5

3.45e-03171532DOID:8677 (biomarker_via_orthology)
Diseasetriglycerides to total lipids in small LDL percentage

PDXDC1 APOB PLCB3

3.59e-03591533EFO_0022337
Diseasefree cholesterol to total lipids in very large VLDL percentage

PDXDC1 TDRD15 APOB

3.59e-03591533EFO_0022289
Diseaseresponse to antipsychotic drug

TNIK DYNC2H1 CDK5RAP2

3.77e-03601533GO_0097332
Diseasecholesterol to total lipids in IDL percentage

PDXDC1 APOB MACF1

3.77e-03601533EFO_0022233
Diseaseleft ventricular mass

PDXDC1 CCDC141

3.87e-03181532EFO_0009289
Diseasevery low density lipoprotein cholesterol measurement, esterified cholesterol measurement

TDRD15 APOB

3.87e-03181532EFO_0008317, EFO_0008589
Diseasefree cholesterol in IDL measurement

PDXDC1 TDRD15 APOB

3.95e-03611533EFO_0022181
Diseasecutaneous melanoma, hair color

PIGU SYNE2 ARHGAP20

4.13e-03621533EFO_0000389, EFO_0003924
Diseasevery low density lipoprotein cholesterol measurement, phospholipids:total lipids ratio

PDXDC1 TDRD15 APOB SYNE2 MACF1 PLCB3

4.21e-032911536EFO_0008317, EFO_0020946
Diseasephospholipids in chylomicrons and extremely large VLDL measurement

PDXDC1 APOB REXO2

4.32e-03631533EFO_0022292
DiseasePR interval

RYR2 MYO3A SYNE2 FER MACF1 CMAHP FERMT2 DNAH11

4.42e-034951538EFO_0004462
Diseasehippocampal volume

TNIK RYR2 RYR3 PARP1 WWC1 DNAH11

4.65e-032971536EFO_0005035
Diseasecoagulation factor measurement

ASPM PCID2

4.77e-03201532EFO_0004634
Diseaseapolipoprotein A 1 measurement

PDXDC1 APOB PIGU MIDEAS ANGPTL3 FER FES MACF1 PLCB3 MGA SMG6

4.82e-0384815311EFO_0004614
Diseasepolyunsaturated fatty acid measurement

PDXDC1 TDRD15 APOB DNAH11

4.89e-031311534EFO_0010733
Diseaselow density lipoprotein cholesterol measurement, physical activity

TDRD15 APOB DNAH11

4.93e-03661533EFO_0003940, EFO_0004611

Protein segments in the cluster

PeptideGeneStartEntry
ALKKNDQEVIISKYL

USP26

531

Q9BXU7
IAKKYIDQKFVLQLL

PPP2R5E

171

Q16537
DSLLQKLQVTYKFKL

SMG6

686

Q86US8
INQIILLKDIIYKVK

CFAP43

1006

Q8NDM7
LLKDIIYKVKTVFNN

CFAP43

1011

Q8NDM7
QFKLKLLLESYTQQK

CCDC112

311

Q8NEF3
LQLQFKKIKANYVCL

CAGE1

406

Q8TC20
KTYQLVYFLDKILQK

RNPEP

531

Q9H4A4
ILKQEIKVFFVKYND

AP2B1

316

P63010
EAKLKEVLLVLKYVQ

CUL5

431

Q93034
KIAVLYLKKNKNLLA

ADAM28

66

Q9UKQ2
LEVFYLIRKQLNKKV

ADORA1

201

P30542
AVKEIKSYLKRIFQL

ALS2

1411

Q96Q42
IIEYLKQQVSLLKEK

AIMP1

21

Q12904
KNSIIQDKKLYIAEL

ARMC2

666

Q8NEN0
ALAIFKKRNTILKYI

DNAH11

746

Q96DT5
YVLQINVLQAKKKFE

ACAP3

171

Q96P50
AKKYIDQKFVLALLD

PPP2R5D

231

Q14738
KKYIDQKFVLQLLEL

PPP2R5C

156

Q13362
LKNQAKLIEFLSKFQ

CAB39

296

Q9Y376
SLLEEKILLQQKVKY

ANGPTL3

126

Q9Y5C1
KILLQQKVKYLEEQL

ANGPTL3

131

Q9Y5C1
NAEKLKDFKIRLQYF

API5

366

Q9BZZ5
EFLLKKKANVNAIDY

ANKRD36

181

A6QL64
KKQEIIKAYRKLALQ

DNAJC3

406

Q13217
LQYNELKLALEKEKA

CIT

1256

O14578
IIKKLIEDNKFYQLE

FAM184A

1006

Q8NB25
EKYLTILKAVKVLQA

ASPM

2161

Q8IZT6
KKENFNLKLRIYFLE

CDK5RAP2

71

Q96SN8
KFYSFLVLKKQLAIE

RAD21L1

521

Q9H4I0
KFYSFLVLKKQQAIE

RAD21

596

O60216
QVNLKYLLKLKFNFK

PARP1

996

P09874
QKLLYQALKNKISIE

INO80

771

Q9ULG1
YFNKISKIENLEKLI

LRRC9

106

Q6ZRR7
TKYLLKLLKAFQIDV

ANKAR

951

Q7Z5J8
EFLLKKKANINAVDY

ANKRD36C

181

Q5JPF3
AKKILYYLRQQKILN

FBXO21

166

O94952
YAIFKVLNEKKLQEV

NOP58

11

Q9Y2X3
KQYRICLKTLKEEFQ

LARGE1

721

O95461
KIQEYIIAFAKEKNL

FMO3

86

P31513
IIAFAKEKNLLKYIQ

FMO3

91

P31513
KLITQDLVKLKYLEY

MAGEB3

246

O15480
EKVDKLVQFLLLKYQ

MAGEC3

186

Q8TD91
LKKLEYIYAKQQALE

MGA

2511

Q8IWI9
RIQIALKYDEKNKQF

WWC1

661

Q8IX03
LKYDEKNKQFAILII

WWC1

666

Q8IX03
NQELGKFKFVLDYKI

CFAP57

966

Q96MR6
LLYEKIKIQQSVLNK

CFAP58

626

Q5T655
IENVLKNIKCRKYAF

INPP4B

886

O15327
AKLVALVNKFIGYLK

GAPVD1

256

Q14C86
IKLLNNKFASFIDKV

KRT4

141

P19013
YDGIKKLLQQLFLKA

BCCIP

71

Q9P287
KYFALRNIIQKFEKV

GLB1

346

P16278
KLIKNDLDLEIQKIY

FSIP2

2361

Q5CZC0
IGLLDEKQKKYFQKQ

CPVL

256

Q9H3G5
FEYLVKGAILLQDKK

EDEM2

261

Q9BV94
VDKYLKEILQDLVKN

ECPAS

1156

Q5VYK3
IIYSLRNKQIKVAIK

OR14C36

286

Q8NHC7
DLEIYQLKKEIQALK

PPL

1266

O60437
RLQESLKKVNYIKIL

PDXDC1

366

Q6P996
LQESLKKVNYIKILV

PDXDC2P

366

Q6P474
LKDVVYKNNDFKLEL

NRXN2

451

Q9P2S2
KKQIIDDFITRNKYL

DNAJC16

346

Q9Y2G8
LKNLKELNVGFNYLK

LRRC2

166

Q9BYS8
KNYFNILDKIVQKVL

FBXO25

146

Q8TCJ0
LYAIKILKKDVIVQD

PRKCG

376

P05129
DNYLFLKEVKNLVEK

PADI2

316

Q9Y2J8
ILQKVLKLKVDYLIA

RICTOR

116

Q6R327
VFKKQKLLLELDQYA

PIGU

106

Q9H490
LIIFLIYKVVQFKQK

LRRC70

541

Q7Z2Q7
KDIIYRVYLKQIIVK

LRRC8B

251

Q6P9F7
EYKVVKAQIQEQKLL

MACF1

5376

Q9UPN3
NKKLAYLIDIKTIAI

IFT172

456

Q9UG01
FIYTLRNKQVKDVFK

OR6C74

286

A6NCV1
ELQFYRNNIFKKKID

REXO2

206

Q9Y3B8
IEKNKKNNVFEYFLL

FANCB

96

Q8NB91
LFAEEQAKNLLEKYK

POP1

671

Q99575
TFLRKAYTKLKLQVN

PLCB3

151

Q01970
LDTIKNLVKKYSQFI

HSP90B1

261

P14625
LVNQLFKIYFKINKL

PCID2

171

Q5JVF3
QLLQAFLKYKELVKR

DYNC2H1

416

Q8NCM8
KQVLDLLKYLVIDNK

ATM

1536

Q13315
LQQVKIKDYFEKLVG

APOB

2381

P04114
KFKTYELTLKDVQNI

HYDIN

2456

Q4G0P3
DVKKRSVYLKVLFNN

CC2D2A

676

Q9P2K1
KILNKYLELDIQAKE

CCDC141

496

Q6ZP82
ELLKKQAQFYENIVK

DOCK1

1316

Q14185
KKLKEYILYLKNNIE

CCDC175

661

P0C221
LRLYKQQVKKLEKAL

CEP70

296

Q8NHQ1
LEQIKLYQNLLAKKR

DNAH17

3021

Q9UFH2
DYEVFLKVLNDNIKK

DNAH3

1666

Q8TD57
LKIKFLQEAKILKQY

FER

601

P16591
NIYKDLQKLSRLFKD

FBXO7

296

Q9Y3I1
TKYFNQLILRLQKEK

CCDC40

646

Q4G0X9
QKLFVKTQLYGFLKE

GCC2

751

Q8IWJ2
FKRKKYIFQLNEIEQ

CCDC160

61

A6NGH7
AIKYFKEKVSTQNLL

APOL1

71

O14791
VALYLQKLKDLEVKQ

CCDC85A

141

Q96PX6
KKLEYLNLALNNIEK

DNAAF11

66

Q86X45
AIYKKDFFLVQKLIQ

MIDEAS

846

Q6PJG2
ENINLFIKKVKNFLL

LAMB4

1476

A4D0S4
FVELKKQYAILQRKT

LAMB4

1666

A4D0S4
YLKKYKNKQITARIL

FERMT2

526

Q96AC1
KKLESFYIQKVLDII

HEXB

381

P07686
KAYVVLGQFLVLKKD

BANF1

41

O75531
ELEYVLNAVLQKKKD

CAPN9

541

O14815
ALSQKKYEQELFKLA

RYR2

2651

Q92736
KFYAVKVLQKKIVLN

SGK3

186

Q96BR1
NVIKEFKKVLISYEL

IZUMO2

116

Q6UXV1
LSIDLYELIKKNKFQ

DYRK3

291

O43781
KSNIEKAAFVKLYLV

FOCAD

1576

Q5VW36
KAKFLQEARILKQYS

FES

601

P07332
LLDVLKSKQYVKVQI

MAP3K4

841

Q9Y6R4
YKLASKEFQNKILFI

PDILT

296

Q8N807
KLLKIFQYTNFEKNR

PGGT1B

281

P53609
LFVVAKIKYNNNFKI

ARHGAP20

111

Q9P2F6
NAYFKQLDELEKVIK

UTRN

801

P46939
IYFKKSQENRIEKFL

SPHKAP

1641

Q2M3C7
RLKTIKQLYEQFIKS

SYCP3

171

Q8IZU3
QFNVIVALAKDKFYK

SYNE1

4651

Q8NF91
LQVLKLKKVFDYIGL

SYNE2

2996

Q8WXH0
YSKIFLIAKQQAIKI

TAAR8

216

Q969N4
AAIDYFKKLVLNKAI

TDRD15

611

B5MCY1
KVKVNVNLLIYLLNK

IQGAP2

1556

Q13576
EVFYAVKVLQKKAIL

SGK1

121

O00141
ILKAAKRFQINIYVK

SCARB2

376

Q14108
KRFQINIYVKKLDDF

SCARB2

381

Q14108
IAEELNKKLANKVVY

POLR3H

26

Q9Y535
LQDLVDKLQLKVKAY

MYH6

1866

P13533
AFRQIKAYEKQIKTL

CDC42BPA

526

Q5VT25
QFIKTERKKLLNYKA

CMAHP

226

Q9Y471
KLQRIVKNLDFIVYK

CHAT

501

P28329
YQLLAKASYKKAIIL

NCAPD2

521

Q15021
NLKVKVAILKYIESL

CLASP1

991

Q7Z460
KVVKVANVSLLALYK

RPS23

121

P62266
KFLVIALKNAVEIYA

TNIK

1156

Q9UKE5
IKTKLFYKQQKFNLL

THOC2

151

Q8NI27
LKADQLYKQKIIRGF

PDHA1

76

P08559
KLARKILQEKVDVFY

MTRFR

106

Q9H3J6
LKKILKYVDSAQEFI

RYR3

2821

Q15413
NSKFDTIYQILLKKK

TRIM25

271

Q14258
ALYVKVQKRFLKSLI

TMTC2

441

Q8N394
QYSALQRIIKKFKVE

TRIM75

281

A6NK02
KQVFQFAVKESLILK

EZH1

466

Q92800
LYKRLKEYAKQELLQ

FSBP

71

O95073
KNIDNFLNRYEKIVK

ROCK2

66

O75116
IIYKFVKNVKLLERI

VPS13C

2556

Q709C8
VNYLKELEKQLVAQK

TTC17

76

Q96AE7
YNISFEKKLLQILSK

ZPBP

186

Q9BS86
LIQLLENYKKKLQEF

TRIM16

321

O95361
FKVAAIQQILGKYKE

TTC37

636

Q6PGP7
VKDKIIQFIQEQLKY

VWA3B

526

Q502W6
VKVLADNKLVIKQEY

TOGARAM1

441

Q9Y4F4
LEILNKLIKYIQIKF

POSTN

641

Q15063
LKDLKVLNLAYNKIN

TLR5

311

O60602
FFQKAKNREYLIEKL

STK39

336

Q9UEW8
DFKEYVISIRQKKLL

TUT4

1201

Q5TAX3
QVLFEAYQIKKTKLD

VPS37B

81

Q9H9H4
YKTQNKFLNKEILEL

TBC1D2B

496

Q9UPU7
KEYLIVAQEALNAKK

WWC3

26

Q9ULE0
LILFQYLKGQVKFKS

THOC1

326

Q96FV9
IQLLENYKKKLQEFS

TRIM16L

106

Q309B1
EDFKKVLQKNVVAYI

NAALADL2

511

Q58DX5
QISKLSEEYFILQKK

MYO3A

1431

Q8NEV4