Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionpeptidyl-lysine N6-myristoyltransferase activity

NMT2 NMT1

2.84e-0521072GO:0018030
GeneOntologyMolecularFunctionglycylpeptide N-tetradecanoyltransferase activity

NMT2 NMT1

2.84e-0521072GO:0004379
GeneOntologyMolecularFunctionalpha-L-arabinofuranosidase activity

OTOGL OTOG

2.84e-0521072GO:0046556
GeneOntologyMolecularFunctionintegrin binding involved in cell-matrix adhesion

ITGA9 EMILIN1

2.81e-0451072GO:0098640
GeneOntologyMolecularFunctionextracellular matrix protein binding

CD248 ITGAV

4.21e-0461072GO:1990430
GeneOntologyMolecularFunctionhistone H3K4me/H3K4me2/H3K4me3 demethylase activity

KDM5C KDM5D

4.21e-0461072GO:0034647
GeneOntologyMolecularFunctionhistone H3 demethylase activity

KDM4C KDM5C KDM5D

4.45e-04281073GO:0141052
GeneOntologyMolecularFunctionhistone demethylase activity

KDM4C KDM5C KDM5D

6.03e-04311073GO:0032452
GeneOntologyMolecularFunctionprotein demethylase activity

KDM4C KDM5C KDM5D

6.63e-04321073GO:0140457
GeneOntologyMolecularFunctionhistone H3K4 demethylase activity

KDM5C KDM5D

7.80e-0481072GO:0032453
GeneOntologyMolecularFunctioncell-matrix adhesion mediator activity

ITGA9 EMILIN1

9.99e-0491072GO:0098634
GeneOntologyMolecularFunctionmyristoyltransferase activity

NMT2 NMT1

1.52e-03111072GO:0019107
GeneOntologyMolecularFunctiondemethylase activity

KDM4C KDM5C KDM5D

1.69e-03441073GO:0032451
GeneOntologyMolecularFunctionextracellular matrix constituent conferring elasticity

EMILIN1 MMRN1

1.81e-03121072GO:0030023
GeneOntologyBiologicalProcesscell adhesion mediated by integrin

ITGA9 ITGAV EMILIN1 MMRN1 PIK3CG RAC3

7.07e-06911056GO:0033627
GeneOntologyBiologicalProcessarabinose metabolic process

OTOGL OTOG

2.57e-0521052GO:0019566
GeneOntologyBiologicalProcessvibrational conductance of sound to the inner ear

OTOGL OTOG

2.57e-0521052GO:0055127
GeneOntologyBiologicalProcessL-arabinose metabolic process

OTOGL OTOG

2.57e-0521052GO:0046373
GeneOntologyBiologicalProcessN-terminal peptidyl-glycine N-myristoylation

NMT2 NMT1

2.57e-0521052GO:0018008
GeneOntologyBiologicalProcessneutrophil migration

CAMK1D ITGA9 PIK3CG UMOD RAC1 RAC3

5.39e-051301056GO:1990266
GeneOntologyBiologicalProcessrespiratory burst

CAMK1D PIK3CG RAC1 RAC3

6.72e-05431054GO:0045730
GeneOntologyBiologicalProcesspeptidyl-glycine modification

NMT2 NMT1

7.68e-0531052GO:0018201
GeneOntologyBiologicalProcessmyeloid leukocyte migration

CAMK1D ITGA9 EMILIN1 NF1 PIK3CG UMOD RAC1 RAC3

8.44e-052761058GO:0097529
GeneOntologyBiologicalProcesspostsynapse assembly

PTPRD PTPRS DOCK7 RAC1 RAC3

1.13e-04931055GO:0099068
GeneOntologyBiologicalProcessN-terminal protein myristoylation

NMT2 NMT1

1.53e-0441052GO:0006499
GeneOntologyBiologicalProcessprotein myristoylation

NMT2 NMT1

1.53e-0441052GO:0018377
GeneOntologyBiologicalProcessRac protein signal transduction

NF1 PIK3CG RAC1 RAC3

2.48e-04601054GO:0016601
GeneOntologyCellularComponentcytoophidium

TNK2 CTPS1

7.62e-0531062GO:0097268
GeneOntologyCellularComponentprotein complex involved in cell adhesion

ITGA9 ITGAV EMILIN1 MMRN1

2.29e-04591064GO:0098636
GeneOntologyCellularComponentextracellular matrix

PRSS1 PRSS2 COL12A1 CD248 EMILIN1 MMRN1 ADAMTS10 OTOGL SULF1 NTN1 OTOG

4.99e-0465610611GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

PRSS1 PRSS2 COL12A1 CD248 EMILIN1 MMRN1 ADAMTS10 OTOGL SULF1 NTN1 OTOG

5.12e-0465810611GO:0030312
GeneOntologyCellularComponentintegrin complex

ITGA9 ITGAV EMILIN1

5.65e-04321063GO:0008305
DomainFN3

COL12A1 PTPRD CSF2RA PTPRF PTPRS MYOM2 EPHA1 IL27RA

8.49e-061851038SM00060
DomainFN3

COL12A1 PTPRD CSF2RA PTPRF PTPRS MYOM2 EPHA1 IL27RA

1.44e-051991038PS50853
DomainJmjN

KDM4C KDM5C KDM5D

1.90e-05101033SM00545
DomainJmjN

KDM4C KDM5C KDM5D

1.90e-05101033PF02375
DomainJMJN

KDM4C KDM5C KDM5D

1.90e-05101033PS51183
DomainJmjN

KDM4C KDM5C KDM5D

1.90e-05101033IPR003349
DomainFN3_dom

COL12A1 PTPRD CSF2RA PTPRF PTPRS MYOM2 EPHA1 IL27RA

2.06e-052091038IPR003961
DomainNMT_1

NMT2 NMT1

3.01e-0521032PS00975
DomainNMT_2

NMT2 NMT1

3.01e-0521032PS00976
DomainNMT_C

NMT2 NMT1

3.01e-0521032PF02799
DomainNMT

NMT2 NMT1

3.01e-0521032PF01233
DomainMyristoylCoA_TrFase_C

NMT2 NMT1

3.01e-0521032IPR022677
DomainMyristoylCoA_TrFase_N

NMT2 NMT1

3.01e-0521032IPR022676
DomainMyristoylCoA_TrFase_CS

NMT2 NMT1

3.01e-0521032IPR022678
DomainMyristoylCoA_TrFase

NMT2 NMT1

3.01e-0521032IPR000903
Domainfn3

COL12A1 PTPRD PTPRF PTPRS MYOM2 EPHA1 IL27RA

3.20e-051621037PF00041
DomainPTPc

PTPN3 PTPRD PTPRF PTPRS

4.49e-05361034SM00194
DomainTYR_PHOSPHATASE_PTP

PTPN3 PTPRD PTPRF PTPRS

6.19e-05391034PS50055
DomainPTPase_domain

PTPN3 PTPRD PTPRF PTPRS

7.55e-05411034IPR000242
DomainY_phosphatase

PTPN3 PTPRD PTPRF PTPRS

7.55e-05411034PF00102
DomainLys_sp_deMease-like_dom

KDM5C KDM5D

1.79e-0441032IPR013637
DomainPLU-1

KDM5C KDM5D

1.79e-0441032PF08429
Domainzf-C5HC2

KDM5C KDM5D

2.98e-0451032PF02928
DomainZnf_C5HC2

KDM5C KDM5D

2.98e-0451032IPR004198
DomainJmjC

KDM4C KDM5C KDM5D

3.03e-04241033PF02373
DomainPTPc_motif

PTPN3 PTPRD PTPRF PTPRS

3.15e-04591034SM00404
DomainTyr_Pase_cat

PTPN3 PTPRD PTPRF PTPRS

3.15e-04591034IPR003595
DomainEGF-like_CS

CD248 ADAM29 LRP1B MMRN1 UMOD NTN1 EPHA1

6.08e-042611037IPR013032
DomainEGF_2

CD248 ADAM29 LRP1B MMRN1 UMOD NTN1 EPHA1

6.65e-042651037PS01186
DomainTyr_Pase_AS

PTPN3 PTPRD PTPRF PTPRS

7.09e-04731034IPR016130
DomainJMJC

KDM4C KDM5C KDM5D

7.19e-04321033PS51184
DomainJmjC_dom

KDM4C KDM5C KDM5D

7.19e-04321033IPR003347
DomainJmjC

KDM4C KDM5C KDM5D

7.88e-04331033SM00558
Domain-

ZNF132 ZNF671 ZNF142 ZBTB33 KLF6 ZNF674 ZBTB47 ZNF343 ZNF285 ZNF792 ZNF548

1.30e-03679103113.30.160.60
DomainTYR_PHOSPHATASE_1

PTPN3 PTPRD PTPRF PTPRS

1.31e-03861034PS00383
DomainEMI

EMILIN1 MMRN1

1.32e-03101032PF07546
DomainTYR_PHOSPHATASE_dom

PTPN3 PTPRD PTPRF PTPRS

1.37e-03871034IPR000387
DomainTYR_PHOSPHATASE_2

PTPN3 PTPRD PTPRF PTPRS

1.37e-03871034PS50056
Domainzf-C2H2

ZNF132 ZNF671 ZNF142 ZBTB33 KLF6 ZNF674 ZBTB47 ZNF343 ZNF285 ZNF792 ZNF548

1.53e-0369310311PF00096
DomainZnf_C2H2/integrase_DNA-bd

ZNF132 ZNF671 ZNF142 ZBTB33 KLF6 ZNF674 ZBTB47 ZNF343 ZNF285 ZNF792 ZNF548

1.54e-0369410311IPR013087
DomainTRYPSIN_SER

PRSS1 PRSS2 HPN KLK9

1.55e-03901034IPR033116
Domain-

PTPN3 PTPRD PTPRF PTPRS

1.68e-039210343.90.190.10
DomainGalactose-bd-like

SPAG4 NTN1 HERC2 EPHA1

1.82e-03941034IPR008979
DomainWWE

DTX1 PARP14

1.92e-03121032PF02825
DomainWWE-dom

DTX1 PARP14

1.92e-03121032IPR004170
DomainWWE

DTX1 PARP14

1.92e-03121032PS50918
DomainEGF_3

CD248 ADAM29 LRP1B MMRN1 UMOD OTOG

1.93e-032351036PS50026
DomainProt-tyrosine_phosphatase-like

PTPN3 PTPRD PTPRF PTPRS

2.20e-03991034IPR029021
DomainTRYPSIN_HIS

PRSS1 PRSS2 HPN KLK9

2.54e-031031034IPR018114
DomainEGF-like_dom

CD248 ADAM29 LRP1B MMRN1 UMOD OTOG

2.57e-032491036IPR000742
DomainEGF-type_Asp/Asn_hydroxyl_site

CD248 LRP1B MMRN1 UMOD

2.82e-031061034IPR000152
DomainTRYPSIN_SER

PRSS1 PRSS2 HPN KLK9

2.82e-031061034PS00135
DomainEGF_1

CD248 ADAM29 LRP1B MMRN1 UMOD NTN1

2.90e-032551036PS00022
DomainTRYPSIN_HIS

PRSS1 PRSS2 HPN KLK9

2.91e-031071034PS00134
Domain-

KDM5C KDM5D

3.02e-031510321.10.150.60
DomainBRIGHT

KDM5C KDM5D

3.02e-03151032SM00501
DomainARID_dom

KDM5C KDM5D

3.02e-03151032IPR001606
DomainARID

KDM5C KDM5D

3.02e-03151032PS51011
DomainARID

KDM5C KDM5D

3.02e-03151032PF01388
DomainEMI_domain

EMILIN1 MMRN1

3.44e-03161032IPR011489
DomainIntegrin_alpha_C_CS

ITGA9 ITGAV

3.44e-03161032IPR018184
DomainPeptidase_S1A

PRSS1 PRSS2 HPN KLK9

3.55e-031131034IPR001314
Domain-

COL12A1 PTPRD CSF2RA PTPRF PTPRS MYOM2 LY9 FCAMR EPHA1 IL27RA

3.61e-03663103102.60.40.10
DomainZINC_FINGER_C2H2_2

ZNF132 ZNF671 ZNF142 ZBTB33 KLF6 ZNF674 ZBTB47 ZNF343 ZNF285 ZNF792 ZNF548

3.63e-0377510311PS50157
DomainKRAB

ZNF132 ZNF671 ZNF674 ZNF343 ZNF285 ZNF792 ZNF548

3.69e-033581037PS50805
DomainKRAB

ZNF132 ZNF671 ZNF674 ZNF343 ZNF285 ZNF792 ZNF548

3.69e-033581037PF01352
DomainZINC_FINGER_C2H2_1

ZNF132 ZNF671 ZNF142 ZBTB33 KLF6 ZNF674 ZBTB47 ZNF343 ZNF285 ZNF792 ZNF548

3.70e-0377710311PS00028
DomainTRYPSIN_DOM

PRSS1 PRSS2 HPN KLK9

3.78e-031151034PS50240
DomainEMI

EMILIN1 MMRN1

3.88e-03171032PS51041
DomainC345C

FRZB NTN1

3.88e-03171032SM00643
DomainTryp_SPc

PRSS1 PRSS2 HPN KLK9

4.02e-031171034SM00020
DomainKRAB

ZNF132 ZNF671 ZNF674 ZNF343 ZNF285 ZNF792 ZNF548

4.34e-033691037SM00349
DomainIntegrin_alpha-2

ITGA9 ITGAV

4.35e-03181032IPR013649
DomainINTEGRIN_ALPHA

ITGA9 ITGAV

4.35e-03181032PS00242
DomainIntegrin_alpha2

ITGA9 ITGAV

4.35e-03181032PF08441
DomainIntegrin_alpha

ITGA9 ITGAV

4.35e-03181032IPR000413
DomainKRAB

ZNF132 ZNF671 ZNF674 ZNF343 ZNF285 ZNF792 ZNF548

4.41e-033701037IPR001909
DomainZnf_C2H2-like

ZNF132 ZNF671 ZNF142 ZBTB33 KLF6 ZNF674 ZBTB47 ZNF343 ZNF285 ZNF792 ZNF548

4.43e-0379610311IPR015880
DomainTrypsin_dom

PRSS1 PRSS2 HPN KLK9

4.53e-031211034IPR001254
DomainTrypsin

PRSS1 PRSS2 HPN KLK9

4.53e-031211034PF00089
DomainEGF_CA

CD248 LRP1B MMRN1 UMOD

4.66e-031221034SM00179
DomainPeptidase_S1_PA

PRSS1 PRSS2 HPN KLK9

4.80e-031231034IPR009003
DomainZnf_C2H2

ZNF132 ZNF671 ZNF142 ZBTB33 KLF6 ZNF674 ZBTB47 ZNF343 ZNF285 ZNF792 ZNF548

4.82e-0380510311IPR007087
DomainNTR

FRZB NTN1

4.84e-03191032PF01759
DomainInt_alpha

ITGA9 ITGAV

4.84e-03191032SM00191
DomainNetrin_module_non-TIMP

FRZB NTN1

4.84e-03191032IPR018933
DomainInt_alpha_beta-p

ITGA9 ITGAV

4.84e-03191032IPR013519
DomainEGF-like_Ca-bd_dom

CD248 LRP1B MMRN1 UMOD

4.93e-031241034IPR001881
DomainZnF_C2H2

ZNF132 ZNF671 ZNF142 ZBTB33 KLF6 ZNF674 ZBTB47 ZNF343 ZNF285 ZNF792 ZNF548

4.95e-0380810311SM00355
DomainEGF

CD248 LRP1B MMRN1 UMOD

5.22e-031261034PF00008
DomainRHO

RAC1 RAC3

5.36e-03201032PS51420
PathwayKEGG_MEDICUS_PATHOGEN_HCMV_GH_TO_ITGA_B_RHOA_SIGNALING_PATHWAY

ITGAV RAC1 RAC3

5.40e-067773M47538
PathwayKEGG_MEDICUS_REFERENCE_ITGA_B_RHOG_RAC_SIGNALING_PATHWAY

ITGA9 ITGAV RAC1 RAC3

1.53e-0528774M47655
PathwayKEGG_MEDICUS_REFERENCE_ITGA_B_FAK_RAC_SIGNALING_PATHWAY

ITGA9 ITGAV RAC1 RAC3

2.02e-0530774M47718
PathwayWP_FOCAL_ADHESION

BIRC3 ITGA9 ITGAV PIK3CG TNK2 RAC1 RAC3

7.10e-05187777MM15913
PathwayREACTOME_SIGNAL_TRANSDUCTION_BY_L1

ITGA9 ITGAV RAC1

1.43e-0419773MM15113
PathwayREACTOME_RECEPTOR_TYPE_TYROSINE_PROTEIN_PHOSPHATASES

PTPRD PTPRF PTPRS

1.67e-0420773M27290
PathwayREACTOME_SYNAPTIC_ADHESION_LIKE_MOLECULES

PTPRD PTPRF PTPRS

1.67e-0420773MM15485
PathwayREACTOME_RECEPTOR_TYPE_TYROSINE_PROTEIN_PHOSPHATASES

PTPRD PTPRF PTPRS

1.67e-0420773MM14991
PathwayREACTOME_SYNAPTIC_ADHESION_LIKE_MOLECULES

PTPRD PTPRF PTPRS

1.94e-0421773M27736
PathwayREACTOME_SIGNAL_TRANSDUCTION_BY_L1

ITGA9 ITGAV RAC1

1.94e-0421773M878
PathwayBIOCARTA_EDG1_PATHWAY

ITGAV PIK3CG RAC1

2.24e-0422773M10579
PathwayPID_INTEGRIN_A9B1_PATHWAY

ITGA9 CSF2RA RAC1

3.31e-0425773M118
PathwayREACTOME_HDMS_DEMETHYLATE_HISTONES

KDM4C KDM5C KDM5D

5.17e-0429773MM14934
Pubmed

LAR receptor phospho-tyrosine phosphatases regulate NMDA-receptor responses.

PTPRD PTPRF PTPRS

2.99e-083109331985401
Pubmed

Trans-synaptic adhesions between netrin-G ligand-3 (NGL-3) and receptor tyrosine phosphatases LAR, protein-tyrosine phosphatase delta (PTPdelta), and PTPsigma via specific domains regulate excitatory synapse formation.

PTPRD PTPRF PTPRS

2.99e-083109320139422
Pubmed

Intact synapse structure and function after combined knockout of PTPδ, PTPσ, and LAR.

PTPRD PTPRF PTPRS

2.99e-083109333656439
Pubmed

The Rac activator DOCK7 regulates neuronal polarity through local phosphorylation of stathmin/Op18.

DOCK7 RAC1 RAC3

2.99e-083109316982419
Pubmed

Developmental expression of the cell adhesion molecule-like protein tyrosine phosphatases LAR, RPTPdelta and RPTPsigma in the mouse.

PTPRD PTPRF PTPRS

2.99e-08310939784606
Pubmed

The LAR/PTP delta/PTP sigma subfamily of transmembrane protein-tyrosine-phosphatases: multiple human LAR, PTP delta, and PTP sigma isoforms are expressed in a tissue-specific manner and associate with the LAR-interacting protein LIP.1.

PTPRD PTPRF PTPRS

1.20e-07410938524829
Pubmed

Multiple interactions between receptor protein-tyrosine phosphatase (RPTP) alpha and membrane-distal protein-tyrosine phosphatase domains of various RPTPs.

PTPRD PTPRF PTPRS

2.98e-075109310777529
Pubmed

Interleukin-1 receptor accessory protein organizes neuronal synaptogenesis as a cell adhesion molecule.

PTPRD PTPRF PTPRS

2.98e-075109322357843
Pubmed

Maturation of ureter-bladder connection in mice is controlled by LAR family receptor protein tyrosine phosphatases.

PTPRD PTPRF PTPRS

5.95e-076109319273906
Pubmed

Intra- and intermolecular interactions between intracellular domains of receptor protein-tyrosine phosphatases.

PTPRD PTPRF PTPRS

1.04e-067109312376545
Pubmed

Modulation of apoptotic response by LAR family phosphatases-cIAP1 signaling during urinary tract morphogenesis.

PTPRD PTPRF PTPRS

1.04e-067109329073098
Pubmed

Combinatorial expression of neurexins and LAR-type phosphotyrosine phosphatase receptors instructs assembly of a cerebellar circuit.

PTPRD PTPRF PTPRS

1.66e-068109337591863
Pubmed

Protein Tyrosine Phosphatase δ Mediates the Sema3A-Induced Cortical Basal Dendritic Arborization through the Activation of Fyn Tyrosine Kinase.

PTPRD PTPRF PTPRS

1.66e-068109328637841
Pubmed

Differential transcriptional regulation of individual TCR V beta segments before gene rearrangement.

PRSS1 PRSS2 TRBV12-3

2.48e-069109311160223
Pubmed

Cell Surface Proteomic Map of HIV Infection Reveals Antagonism of Amino Acid Metabolism by Vpu and Nef.

CD248 LANCL2 PTPRF PTPRS LY9 IL27RA

3.92e-06132109626439863
Pubmed

PTPσ functions as a presynaptic receptor for the glypican-4/LRRTM4 complex and is essential for excitatory synaptic transmission.

PTPRD PTPRF PTPRS

4.85e-0611109325624497
Pubmed

A novel receptor-type protein tyrosine phosphatase with a single catalytic domain is specifically expressed in mouse brain.

PTPRD PTPRF PTPRS

4.85e-061110937832766
Pubmed

Liprins, a family of LAR transmembrane protein-tyrosine phosphatase-interacting proteins.

PTPRD PTPRF PTPRS

6.45e-061210939624153
Pubmed

Comparative interactome analysis of α-arrestin families in human and Drosophila.

KDM5C GTF3C3 NF1 PTPRF PTPRS DOCK7 HERC2 ARRDC2

6.80e-06313109838270169
Pubmed

Myristoylation as a target for inhibiting HIV assembly: unsaturated fatty acids block viral budding.

NMT2 NMT1

9.73e-062109212244217
Pubmed

Rac-deficient cerebellar granule neurons die before they migrate to the internal granule layer.

RAC1 RAC3

9.73e-062109236050459
Pubmed

Rac1 and Rac3 have opposite functions in Schwann cells during developmental myelination.

RAC1 RAC3

9.73e-062109233812927
Pubmed

Identification of a Protein Network Driving Neuritogenesis of MGE-Derived GABAergic Interneurons.

RAC1 RAC3

9.73e-062109228066185
Pubmed

Dissection of the interplay between class I PI3Ks and Rac signaling in phagocytic functions.

PIK3CG RAC1

9.73e-062109220852826
Pubmed

Human immunodeficiency virus type 1 protease triggers a myristoyl switch that modulates membrane binding of Pr55(gag) and p17MA.

NMT2 NMT1

9.73e-06210929971769
Pubmed

Antimyristoylation of the gag proteins in the human immunodeficiency virus-infected cells with N-myristoyl glycinal diethylacetal resulted in inhibition of virus production.

NMT2 NMT1

9.73e-06210922692561
Pubmed

Mouse H-Y encoding Smcy gene and its X chromosomal homolog Smcx.

KDM5C KDM5D

9.73e-062109210441747
Pubmed

Inefficient purifying selection: the mammalian Y chromosome in the rodent genus Mus.

KDM5C KDM5D

9.73e-062109216416087
Pubmed

Chemical characterization of p17gag from human immunodeficiency virus as an N-terminally myristoylated protein.

NMT2 NMT1

9.73e-06210922737204
Pubmed

Dispensable role of Rac1 and Rac3 after cochlear hair cell specification.

RAC1 RAC3

9.73e-062109237204479
Pubmed

Human lymphocyte cDNA ordered library analyzed by 2D gel electrophoresis. 3. Analysis of individual clones.

GTF3C3 EEF1B2

9.73e-06210928573604
Pubmed

Quantitative fluorescence resonance energy transfer microscopy analysis of the human immunodeficiency virus type 1 Gag-Gag interaction: relative contributions of the CA and NC domains and membrane binding.

NMT2 NMT1

9.73e-062109219403686
Pubmed

Rac1 and Rac3 GTPases differently influence the morphological maturation of dendritic spines in hippocampal neurons.

RAC1 RAC3

9.73e-062109231369617
Pubmed

Automated fluorescence lifetime imaging plate reader and its application to Förster resonant energy transfer readout of Gag protein aggregation.

NMT2 NMT1

9.73e-062109223184449
Pubmed

Entropic switch regulates myristate exposure in the HIV-1 matrix protein.

NMT2 NMT1

9.73e-062109214699046
Pubmed

Global profiling of co- and post-translationally N-myristoylated proteomes in human cells.

NMT2 NMT1

9.73e-062109225255805
Pubmed

Genetic variation in salt taste receptors impact salt intake and blood pressure.

TRPV1 SCNN1B

9.73e-062109236899055
Pubmed

Mutations of histone demethylase genes encoded by X and Y chromosomes, Kdm5c and Kdm5d, lead to noncompaction cardiomyopathy in mice.

KDM5C KDM5D

9.73e-062109232081420
Pubmed

The mouse gene Ptprf encoding the leukocyte common antigen-related molecule LAR: cloning, characterization, and chromosomal localization.

PTPRD PTPRF

9.73e-06210927665159
Pubmed

Pancreatitis-Associated PRSS1-PRSS2 Haplotype Alters T-Cell Receptor Beta (TRB) Repertoire More Strongly Than PRSS1 Expression.

PRSS1 PRSS2

9.73e-062109236191639
Pubmed

Immunosuppression and Aberrant T Cell Development in the Absence of N-Myristoylation.

NMT2 NMT1

9.73e-062109226423150
Pubmed

Nef protein of human immunodeficiency virus type 1 binds its own myristoylated N-terminus.

NMT2 NMT1

9.73e-062109217261081
Pubmed

Myristoylation of gag proteins of HIV-1 plays an important role in virus assembly.

NMT2 NMT1

9.73e-06210922194551
Pubmed

Role of the Common PRSS1-PRSS2 Haplotype in Alcoholic and Non-Alcoholic Chronic Pancreatitis: Meta- and Re-Analyses.

PRSS1 PRSS2

9.73e-062109233202925
Pubmed

Opposing effects of human immunodeficiency virus type 1 matrix mutations support a myristyl switch model of gag membrane targeting.

NMT2 NMT1

9.73e-062109210074105
Pubmed

Structure of the anchor-domain of myristoylated and non-myristoylated HIV-1 Nef protein.

NMT2 NMT1

9.73e-062109210339411
Pubmed

Membrane binding of human immunodeficiency virus type 1 matrix protein in vivo supports a conformational myristyl switch mechanism.

NMT2 NMT1

9.73e-06210929261380
Pubmed

Differential membrane binding of the human immunodeficiency virus type 1 matrix protein.

NMT2 NMT1

9.73e-06210928970978
Pubmed

N-myristoyltransferase 1 is essential in early mouse development.

NMT2 NMT1

9.73e-062109215753093
Pubmed

Rac1 and Rac3 GTPases regulate the development of hilar mossy cells by affecting the migration of their precursors to the hilus.

RAC1 RAC3

9.73e-062109221949760
Pubmed

Pre-diagnostic levels of anionic trypsinogen, cationic trypsinogen, and pancreatic secretory trypsin inhibitor in relation to pancreatic cancer risk.

PRSS1 PRSS2

9.73e-062109220484960
Pubmed

Binding of human immunodeficiency virus type 1 Gag to membrane: role of the matrix amino terminus.

NMT2 NMT1

9.73e-062109210196310
Pubmed

A mouse Y chromosome gene encoded by a region essential for spermatogenesis and expression of male-specific minor histocompatibility antigens.

KDM5C KDM5D

9.73e-06210927524912
Pubmed

Loss of Either Rac1 or Rac3 GTPase Differentially Affects the Behavior of Mutant Mice and the Development of Functional GABAergic Networks.

RAC1 RAC3

9.73e-062109226582364
Pubmed

Myristoylation-dependent replication and assembly of human immunodeficiency virus 1.

NMT2 NMT1

9.73e-06210922405382
Pubmed

Matrix-induced inhibition of membrane binding contributes to human immunodeficiency virus type 1 particle assembly defects in murine cells.

NMT2 NMT1

9.73e-062109216306631
Pubmed

The biology and enzymology of protein N-myristoylation.

NMT2 NMT1

9.73e-062109211527981
Pubmed

Rac-Dependent Signaling from Keratinocytes Promotes Differentiation of Intradermal White Adipocytes.

RAC1 RAC3

9.73e-062109231351086
Pubmed

The effect of HIV-1 Gag myristoylation on membrane binding.

NMT2 NMT1

9.73e-062109216183191
Pubmed

Roles of the Rac1 and Rac3 GTPases in human tumor cell invasion.

RAC1 RAC3

9.73e-062109216027728
Pubmed

A second mammalian N-myristoyltransferase.

NMT2 NMT1

9.73e-06210929506952
Pubmed

Alcohol Consumption and Cigarette Smoking are Important Modifiers of the Association Between Acute Pancreatitis and the PRSS1-PRSS2 Locus in Men.

PRSS1 PRSS2

9.73e-062109227846138
Pubmed

Cellular inhibitor of apoptosis protein 2 controls human colonic epithelial restitution, migration, and Rac1 activation.

BIRC3 RAC1

9.73e-062109225394657
Pubmed

Efficient particle formation can occur if the matrix domain of human immunodeficiency virus type 1 Gag is substituted by a myristylation signal.

NMT2 NMT1

9.73e-06210927521919
Pubmed

Blockage of N-myristoylation of HIV-1 gag induces the production of impotent progeny virus.

NMT2 NMT1

9.73e-06210929299393
Pubmed

Biochemical indication for myristoylation-dependent conformational changes in HIV-1 Nef.

NMT2 NMT1

9.73e-062109216475823
Pubmed

Rac1 and Rac3 isoform activation is involved in the invasive and metastatic phenotype of human breast cancer cells.

RAC1 RAC3

9.73e-062109216280046
Pubmed

RAC1B function is essential for breast cancer stem cell maintenance and chemoresistance of breast tumor cells.

RAC1 RAC3

9.73e-062109236599922
Pubmed

Interaction between trypsinogen isoforms in genetically determined pancreatitis: mutation E79K in cationic trypsin (PRSS1) causes increased transactivation of anionic trypsinogen (PRSS2).

PRSS1 PRSS2

9.73e-062109214695529
Pubmed

Two N-myristoyltransferase isozymes play unique roles in protein myristoylation, proliferation, and apoptosis.

NMT2 NMT1

9.73e-062109216123142
Pubmed

Absence of Rac1 and Rac3 GTPases in the nervous system hinders thymic, splenic and immune-competence development.

RAC1 RAC3

9.73e-062109221469092
Pubmed

Gene conversion between functional trypsinogen genes PRSS1 and PRSS2 associated with chronic pancreatitis in a six-year-old girl.

PRSS1 PRSS2

9.73e-062109215776435
Pubmed

Role of capsid precursor processing and myristoylation in morphogenesis and infectivity of human immunodeficiency virus type 1.

NMT2 NMT1

9.73e-06210922788277
Pubmed

Rac1 and Rac3 have opposing functions in cell adhesion and differentiation of neuronal cells.

RAC1 RAC3

9.73e-062109217244648
Pubmed

Genetic disruption of the small GTPase RAC1 prevents plexiform neurofibroma formation in mice with neurofibromatosis type 1.

NF1 RAC1

9.73e-062109232471868
Pubmed

Ack kinase regulates CTP synthase filaments during Drosophila oogenesis.

TNK2 CTPS1

9.73e-062109225223282
Pubmed

N-Myristoyltransferase isozymes exhibit differential specificity for human immunodeficiency virus type 1 Gag and Nef.

NMT2 NMT1

9.73e-062109218089753
Pubmed

Complete inhibition of human immunodeficiency virus Gag myristoylation is necessary for inhibition of particle budding.

NMT2 NMT1

9.73e-06210928576268
Pubmed

Total chemical synthesis of N-myristoylated HIV-1 matrix protein p17: structural and mechanistic implications of p17 myristoylation.

NMT2 NMT1

9.73e-062109215280532
Pubmed

Analysis of mutation rates in the SMCY/SMCX genes shows that mammalian evolution is male driven.

KDM5C KDM5D

9.73e-06210929060413
Pubmed

The second catalytic domain of protein tyrosine phosphatase delta (PTP delta) binds to and inhibits the first catalytic domain of PTP sigma.

PTPRD PTPRS

9.73e-06210929566880
Pubmed

Hereditary pancreatitis caused by a double gain-of-function trypsinogen mutation.

PRSS1 PRSS2

9.73e-062109218461367
Pubmed

Expression of tumor-associated trypsinogens (TAT-1 and TAT-2) in prostate cancer.

PRSS1 PRSS2

9.73e-062109215651064
Pubmed

Retroviral matrix domains share electrostatic homology: models for membrane binding function throughout the viral life cycle.

NMT2 NMT1

9.73e-062109216216583
Pubmed

Hepsin-mediated Processing of Uromodulin is Crucial for Salt-sensitivity and Thick Ascending Limb Homeostasis.

HPN UMOD

9.73e-062109231444371
Pubmed

Similar phenotypes caused by mutations in OTOG and OTOGL.

OTOGL OTOG

9.73e-062109224378291
Pubmed

Perivascular deletion of murine Rac reverses the ratio of marrow arterioles and sinusoid vessels and alters hematopoiesis in vivo.

RAC1 RAC3

9.73e-062109225824687
Pubmed

Myristoylation of human immunodeficiency virus type 1 gag protein is required for efficient env protein transportation to the surface of cells.

NMT2 NMT1

9.73e-062109211302743
Pubmed

Identification of a membrane-binding domain within the amino-terminal region of human immunodeficiency virus type 1 Gag protein which interacts with acidic phospholipids.

NMT2 NMT1

9.73e-06210928139035
Pubmed

Immunoreactive anionic and cationic trypsin in human serum.

PRSS1 PRSS2

9.73e-06210922598466
Pubmed

A myristoyl switch regulates membrane binding of HIV-1 Gag.

NMT2 NMT1

9.73e-062109214707265
Pubmed

Trypsinogen (PRSS1 and PRSS2) gene dosage correlates with pancreatitis risk across genetic and transgenic studies: a systematic review and re-analysis.

PRSS1 PRSS2

9.73e-062109235089416
Pubmed

Trypsinogen copy number mutations in patients with idiopathic chronic pancreatitis.

PRSS1 PRSS2

9.73e-062109218063422
Pubmed

Protein tyrosine phosphatases expression during development of mouse superior colliculus.

PTPRD PTPRF PTPRS

1.97e-0517109319727691
Pubmed

Autocrine extra-pancreatic trypsin 3 secretion promotes cell proliferation and survival in esophageal adenocarcinoma.

PRSS1 PRSS2

2.91e-053109224146905
Pubmed

Isoform-specific membrane targeting mechanism of Rac during Fc gamma R-mediated phagocytosis: positive charge-dependent and independent targeting mechanism of Rac to the phagosome.

RAC1 RAC3

2.91e-053109216081809
Pubmed

Signaling and cytoskeletal requirements in erythroblast enucleation.

RAC1 RAC3

2.91e-053109222461493
Pubmed

Trypsin-mediated enzymatic degradation of type II collagen in the human vitreous.

PRSS1 PRSS2

2.91e-053109223882137
Pubmed

Annexin 2: a novel human immunodeficiency virus type 1 Gag binding protein involved in replication in monocyte-derived macrophages.

NMT2 NMT1

2.91e-053109216501079
Pubmed

Frontline Science: Coincidental null mutation of Csf2rα in a colony of PI3Kγ-/- mice causes alveolar macrophage deficiency and fatal respiratory viral infection.

CSF2RA PIK3CG

2.91e-053109227468760
GeneFamilyFibronectin type III domain containing

COL12A1 PTPRD PTPRF PTPRS MYOM2 EPHA1 IL27RA

6.33e-06160797555
GeneFamilyProtein tyrosine phosphatases, receptor type

PTPRD PTPRF PTPRS

1.01e-0421793813
GeneFamilyPHD finger proteins|Lysine demethylases

KDM4C KDM5C KDM5D

1.52e-0424793485
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZNF132 ZNF671 ZNF142 ZBTB33 KLF6 ZNF674 ZBTB47 ZNF343 ZNF285 ZNF792 ZNF548

2.77e-04718791128
GeneFamilyEMI domain containing

EMILIN1 MMRN1

3.90e-047792540
GeneFamilyAT-rich interaction domain containing

KDM5C KDM5D

1.91e-0315792418
GeneFamilyProteases, serine

PRSS1 PRSS2 HPN

2.64e-0363793738
GeneFamilyCD molecules|Integrin alpha subunits

ITGA9 ITGAV

2.76e-03187921160
GeneFamilyRho family GTPases

RAC1 RAC3

3.40e-0320792390
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

PTPRD PTPRF PTPRS MYOM2

5.42e-03161794593
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL12A1 LRP1B PTPRD OTOGL MYOM2 ANO3 HYDIN OTOG DNAH11

7.89e-1018410992cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL12A1 LRP1B PTPRD OTOGL MYOM2 ANO3 HYDIN OTOG DNAH11

7.89e-101841099ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL12A1 LRP1B PTPRD OTOGL MYOM2 ANO3 HYDIN OTOG DNAH11

7.89e-1018410992b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

INTS6L CD248 ZNF674 GPR173 EMILIN1 ADAMTS10 ANO3

2.65e-071761097b4a23d8d1414434adeb237a96f28c825f1aebd77
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

INTS6L CD248 ZNF674 GPR173 EMILIN1 ADAMTS10 ANO3

2.65e-07176109766c9c6b59030f67e8d746a9c6930e50923f2ded1
ToppCell367C-Endothelial_cells-Endothelial-F_(Lymphatics)|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

DTX1 ITGA9 EMILIN1 MMRN1 PTPN3 SCNN1B NTN1

4.77e-0719210975e709c0714e8eba27e03a6def0544256bedb3ced
ToppCell368C-Endothelial_cells-Endothelial-F_(Lymphatics)|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

DTX1 ITGA9 MMRN1 PTPN3 PTPRF SCNN1B NTN1

4.77e-071921097b016e229300c183e14c0e2bba494bf49c7899112
ToppCell368C-Endothelial_cells-Endothelial-F_(Lymphatics)-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

DTX1 ITGA9 MMRN1 PTPN3 PTPRF SCNN1B NTN1

4.77e-071921097ac96831492c62ad9e1f7d0b764fbdf7d8a189ad9
ToppCell367C-Endothelial_cells-Endothelial-F_(Lymphatics)-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

DTX1 ITGA9 EMILIN1 MMRN1 PTPN3 SCNN1B NTN1

4.77e-0719210975f4f44f15d3a2846981e68296643a4634930a211
ToppCell(6)_Endothelial_cells-(6)_Endothelial-F_(Lymphatics)|(6)_Endothelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)

DTX1 ITGA9 EMILIN1 MMRN1 PTPN3 SCNN1B NTN1

5.11e-0719410979441202d6fa2ffbef9277d48ae9bc98876c26ec5
ToppCellCOPD-Endothelial-Lymphatic|Endothelial / Disease state, Lineage and Cell class

KLF6 DTX1 ITGA9 MMRN1 PTPN3 STOX2 NTN1

5.29e-071951097e91ce548ae7224661ee5d2f2639794a5f69798ee
ToppCellIPF-Endothelial-Lymphatic|Endothelial / Disease state, Lineage and Cell class

DTX1 ITGA9 EMILIN1 MMRN1 PTPN3 STOX2 NTN1

5.29e-071951097de88e9d22044b4b3e29676ad02b3e9299cc920ad
ToppCellEndothelial_cells-Endothelial-B|Endothelial_cells / lung cells shred on cell class, cell subclass, sample id

DTX1 ITGA9 EMILIN1 MMRN1 PTPN3 STOX2 NTN1

5.48e-07196109736f95f9ef74eb951e41ef46fd136ceaef45208fc
ToppCellLeuk-UTI-Lymphocyte-T_NK-Treg|Leuk-UTI / Disease, Lineage and Cell Type

PRSS1 BIRC3 ITGA9 PTPN3 STOX2 NMT2

2.13e-061531096b24c693b142206d13b29c96faa7f79a1a22bc2ef
ToppCellfacs-Brain_Myeloid-Cerebellum_|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL12A1 IRF7 PARP14 LARS2 CSF2RA LY9

2.86e-0616110965c762609531a7c5505aa5637abf8e0311568d7fd
ToppCellfacs-Brain_Myeloid-Cerebellum_-18m|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL12A1 IRF7 PARP14 LARS2 CSF2RA LY9

2.86e-061611096b14a83ad07a7acb07c766aa862b527698976b6fc
ToppCellfacs-Brain_Myeloid-Cerebellum_-18m-Myeloid|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL12A1 IRF7 PARP14 LARS2 CSF2RA LY9

2.86e-061611096c5d9d47dcedfbb1ac77f4afaf860ae4d9f26fd3f
ToppCellfacs-Brain_Myeloid-Cerebellum_-18m-Myeloid-nan|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL12A1 IRF7 PARP14 LARS2 CSF2RA LY9

2.86e-06161109626c0d876339bfd34d9a43af5b9fb08f50526f2c9
ToppCellfacs-Brain_Myeloid-Cerebellum_-18m-Myeloid-microglial_cell|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL12A1 IRF7 PARP14 LARS2 CSF2RA LY9

3.41e-0616610964ab1959c526c2fd83077fc03e4de207f34841a19
ToppCellAdult-Endothelial-endothelial_cell_of_lymph_vessel-D122|Adult / Lineage, Cell type, age group and donor

DTX1 ITGA9 SH2D5 MMRN1 STOX2 NTN1

4.32e-061731096dba09ba9748871e38a16449d500ae4d7b405c42f
ToppCellfacs-Pancreas-Exocrine-24m|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRSS2 COL12A1 LRP1B OTOGL HPN UMOD

5.43e-06180109672310baeed848f2c483ae986cd73d2fb2cca7feb
ToppCell367C-Endothelial_cells-Endothelial-F_(Lymphatics)-|367C / Donor, Lineage, Cell class and subclass (all cells)

DTX1 ITGA9 MMRN1 STOX2 SCNN1B NTN1

5.60e-061811096b244ecaa442bbef51289d8ec574ef08fa9e96318
ToppCell367C-Endothelial_cells-Endothelial-F_(Lymphatics)|367C / Donor, Lineage, Cell class and subclass (all cells)

DTX1 ITGA9 MMRN1 STOX2 SCNN1B NTN1

5.60e-061811096dd79de8098edb385a0f85d0e9621503cdf76ec43
ToppCelldroplet-Kidney-nan-21m-Epithelial-Pecam____kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANKK1 CD248 SULF1 MRC2 MYOM2 HYDIN

5.97e-061831096f55081068213cc1cdb2acad58ff10f6b48b44c72
ToppCellCOVID-19-Epithelial_cells-Airway_club|COVID-19 / group, cell type (main and fine annotations)

ITGA9 PTPN3 STOX2 PTPRD SCNN1B NTN1

6.35e-061851096cfe6fd73d817e173fe803bc1683c291d9bcb8608
ToppCellEndothelial-endothelial_cell_of_lymph_vessel|World / Lineage, Cell type, age group and donor

DTX1 ITGA9 MMRN1 PTPN3 STOX2 NTN1

6.96e-06188109680910dcbb51990f2baed240f319456c0d3fa2065
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel|Children_(3_yrs) / Lineage, Cell type, age group and donor

DTX1 ITGA9 MMRN1 PTPN3 STOX2 NTN1

6.96e-061881096c2805232618a7b6f844d34e37ad458a9923dbfe1
ToppCellfacs-Pancreas-Endocrine-24m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PAPSS2 ITGAV EMILIN1 PTPRF FRZB SCNN1B

6.96e-061881096a91443aa8fa8fa87f7501c59219daa0305bd0bbf
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

DTX1 ITGA9 MMRN1 PTPN3 STOX2 NTN1

6.96e-061881096aeecbc057dc823f8fcea8a98f18d213bacc7f4db
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_lymph_vessel|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DTX1 ITGA9 MMRN1 PTPN3 STOX2 NTN1

7.18e-06189109655a1776a4ce049959b3f13a43744c7314bc1f00a
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

KLF6 ITGAV STOX2 MRC2 HYDIN DNAH11

7.18e-061891096bd91bdfe35294e60d980259b70fe9e60dca2743f
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

DTX1 ITGA9 MMRN1 PTPN3 STOX2 NTN1

7.40e-0619010966e6ce6dd549d1c38cfef5b3f8be06ab01ce344b7
ToppCellfacs-Pancreas-Endocrine-24m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PAPSS2 EMILIN1 PTPRF FRZB SCNN1B SYT4

7.62e-0619110963387b95a3f2445c672d407922fdce3a91eabaef8
ToppCellControl-Endothelial-Lymphatic|World / Disease state, Lineage and Cell class

DTX1 ITGA9 MMRN1 PTPN3 STOX2 NTN1

7.85e-061921096f95fb188aa642f3d0618242a770e7c4b70544adb
ToppCellILEUM-inflamed-(7)_Endothelial_cell-(7)_Lymphatics|(7)_Endothelial_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

KLF6 DTX1 EMILIN1 MMRN1 SCNN1B NTN1

7.85e-061921096d43caf42ec744e895137f31ef65a990e250669d2
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL12A1 CD248 EMILIN1 SULF1 MRC2 FRZB

8.09e-061931096dc8e62df6121ee99b156aca6b1b3ae555739b6f2
ToppCellControl-Endothelial-Lymphatic|Control / Disease state, Lineage and Cell class

DTX1 ITGA9 MMRN1 PTPN3 STOX2 NTN1

8.09e-06193109664d19be73e5432d491436a01da5de5c926b615a9
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_119|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL12A1 CD248 EMILIN1 SULF1 MRC2 FRZB

8.09e-061931096e2ee077fd381bd906e6b4329f22e7d106e422a7f
ToppCellfacs-Heart-RA-18m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD248 EMILIN1 ADAMTS10 SULF1 MRC2 FRZB

8.33e-061941096bc945450b350f597c3ff910d3a14a533d90086a8
ToppCellfacs-Heart-RA-18m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD248 EMILIN1 ADAMTS10 SULF1 MRC2 FRZB

8.58e-061951096690d6e15d7c863fc8f2d33b1f7bf86f019f415c9
ToppCellfacs-Pancreas-Endocrine-18m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PAPSS2 ITGAV EMILIN1 FRZB SCNN1B SYT4

8.58e-061951096bd8e24dd598990204998d1dd853ba7a53dc0107e
ToppCellfacs-Heart-RA-18m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD248 EMILIN1 ADAMTS10 SULF1 MRC2 FRZB

8.58e-0619510965c05e2bcea3d5d7ebe6325f7187ccf83301053d8
ToppCelldistal-Endothelial-Lymphatic|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

DTX1 EMILIN1 MMRN1 PTPN3 SCNN1B NTN1

8.83e-0619610963e8a20e1d163dcbd3bbd99fe179d54af02298af0
ToppCellfacs-Aorta-Heart-3m-Mesenchymal-fibroblast_of_cardiac_tissue|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD248 LARS2 PTPRF PTPRS DOCK7 NTN1

8.83e-0619610962029f58ce6a7b8c35d3a7496c3341391990909ce
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL12A1 CD248 EMILIN1 SULF1 MRC2 FRZB

9.09e-0619710964cf4e9553397cd8dee883dbec24f41bec41aff99
ToppCell3'-Child09-12-SmallIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL12A1 LANCL2 EMILIN1 SULF1 FRZB PRRG3

9.36e-061981096d83707b69fb64721ac3cff90ba58cdd999d6b386
ToppCell10x3'2.3-week_14-16-Mesenchymal_osteo-stroma-early_osteoblast|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

COL12A1 CD248 DELEC1 EMILIN1 PTPRD MRC2

9.36e-0619810966a539d3b47bd2d4a7ad5c67cad23facffc0ac45f
ToppCellTransplant_Alveoli_and_parenchyma-Endothelial-Lymphatic|Endothelial / Tissue, Lineage and Cell class of Lung Cells from 10X

DTX1 ITGA9 EMILIN1 MMRN1 PTPN3 SCNN1B

9.36e-0619810967a99c341736a4a2ac48ef8e2f7951f21a7378946
ToppCellParenchymal-10x3prime_v2-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

ZBTB33 LANCL2 PTPRS MPC1 MYOM2 ZNF548

9.36e-061981096cc2b5b632e73e44bb60050f0db10d8f0dbb859fa
ToppCellControl-Control-Lymphocyte-T/NK-CD4+_T_activated|Control / Disease, condition lineage and cell class

ZNF132 ZNF343 BIRC3 ZNF285 PLEKHG5 MRC2

9.36e-061981096ee71543559836fd59adc0da877b2ca538cba60cb
ToppCellmetastatic_Brain-Fibroblasts-FB-like_cells|metastatic_Brain / Location, Cell class and cell subclass

COL12A1 CD248 EMILIN1 SULF1 MRC2 FRZB

9.63e-06199109612133087eae9f0e9b6c13a71e8187117768e64ce
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW09-Neuronal-Interneuron|GW09 / Sample Type, Dataset, Time_group, and Cell type.

ZNF285 LRP1B SRRD FRZB PRRG3 ARRDC2

9.91e-062001096a6500d0d2e8bcac92381ab771dbdee66b0e1d48e
ToppCelltumor_Lymph_Node_/_Brain-Fibroblasts|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

COL12A1 CD248 EMILIN1 SULF1 MRC2 FRZB

9.91e-0620010964f7e26b27bd51c32420ed8c2f52d070aee542159
ToppCelltumor_Lymph_Node_/_Brain-Fibroblasts-Myofibroblasts|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

COL12A1 CD248 EMILIN1 SULF1 MRC2 FRZB

9.91e-062001096ca777a7d001848f6d01c613ff2bda7e4f3e20521
ToppCellBronchial-10x5prime-Stromal-Fibroblastic|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

COL12A1 CD248 EMILIN1 PTPRS SULF1 MRC2

9.91e-0620010966316c288022719b9e6c4332c5cb9041e1188d0e8
ToppCellBiopsy_IPF-Mesenchymal|Biopsy_IPF / Sample group, Lineage and Cell type

COL12A1 CD248 EMILIN1 SULF1 MRC2 FRZB

9.91e-062001096bb605b373caf3f873dc1b87d712704568e0d6040
ToppCellPND01-03-samps-Mesenchymal-Matrix_fibroblast-matrix_-_mature_3|PND01-03-samps / Age Group, Lineage, Cell class and subclass

ZBTB47 LANCL2 SH2D5 MMRN1 TNK2

2.20e-0513710959bfdbc102cdd861996b3c4eac35b606be8af97eb
ToppCellmild_COVID-19-B_cell|World / disease group, cell group and cell class (v2)

ANKK1 CAMK1D DTX1 BIRC3 ZNF285

2.71e-0514310954698cc877dda9b1ef7d6f18c9adc869ef791b1d8
ToppCellfacs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANKK1 LARS2 LRP1B OTOGL HYDIN

2.89e-05145109596712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCell10x5'-Liver-Myeloid_Mac-Intestinal_macrophages|Liver / Manually curated celltypes from each tissue

GPR173 ITGA9 LRP1B EMILIN1 MRC2

4.11e-0515610959a897fc79c4fae94c5f2e9012d65297f9225e5e3
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Fibroblasts|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DTX1 GPR173 PTPRF SULF1 NTN1

4.23e-051571095f086753b51860e23f1275bd75e8802d2a7d7b70a
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_B-Plasma_Cell-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SPAG4 PIK3CG SCNN1B LY9 RWDD2A

4.36e-0515810956b51e5ee08e23924f5edbaf0a845a9232fb7ff7a
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_B-Plasma_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SPAG4 PIK3CG SCNN1B LY9 RWDD2A

4.36e-0515810958dd83a2a4c2ec9cdc3a03df8b51ee22bee1c2888
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANKK1 COL12A1 LRP1B SULF1 HYDIN

4.63e-051601095c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANKK1 COL12A1 LRP1B SULF1 HYDIN

4.63e-05160109525c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellBasal_cells-Donor_04|World / lung cells shred on cell class, cell subclass, sample id

MYOZ3 LRP1B PTPRS FAM157C PRRG3

4.63e-051601095b223cc47e68a29df4758c5ccf8f6dbffe2a6fa1d
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LARS2 LRP1B ABCA5 OTOGL HYDIN

4.91e-051621095bf886e22ff2a20353499004b53f25fb9e6574896
ToppCellfacs-Lung-nan-3m-Epithelial-type_I_pneumocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRMPD1 NUDT12 PTPN3 ABCA5 SCNN1B

5.52e-05166109511b0ae82b3068ef91715dbdd49fe8e9791b4a480
ToppCellfacs-Lung-nan-3m-Epithelial-Alveolar_Epithelial_Type_1|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRMPD1 NUDT12 PTPN3 ABCA5 SCNN1B

5.52e-051661095fcc1aec31ebd39432d4cb284dc8fadf34e3c566a
ToppCellEndothelial-B-Donor_04|World / lung cells shred on cell class, cell subclass, sample id

MYOZ3 MMRN1 ZNF792 SULF1 NTN1

5.68e-0516710956a03d16165e0b003092c39972928981abd4a75aa
ToppCellfacs-Lung-3m-Epithelial-alveolar_epithelial-type_I_pneumocyte|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FRMPD1 NUDT12 PTPRF ABCA5 SCNN1B

5.68e-051671095bebc2493a2ee41920b21c2b774a1c5a9619315c4
ToppCellfacs-Lung-3m-Epithelial-alveolar_epithelial-type_I_pneumocyte-type_1_alveolar_epithelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FRMPD1 NUDT12 PTPRF ABCA5 SCNN1B

5.68e-0516710959f2661729a2d58e17a9203a563d538c08a3dbbbc
ToppCelldroplet-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MYOZ3 PARP14 LANCL2 SH2D5 HERC2

5.68e-051671095774f3264318b002d0df5d06d41d645366038d0bf
ToppCellTCGA-Bile_Duct-Primary_Tumor-Cholangiocarcinoma-Intrahepatic-2|TCGA-Bile_Duct / Sample_Type by Project: Shred V9

BIRC3 ITGAV ADAMTS10 PTPRD PTPRS

5.84e-051681095c70bf73bb800e4722cedc35bbc17ea3113d1012d
ToppCell368C-Endothelial_cells-Endothelial-F_(Lymphatics)|368C / Donor, Lineage, Cell class and subclass (all cells)

ITGA9 MMRN1 STOX2 SCNN1B NTN1

5.84e-051681095a74c8a9e3299183fba31ce3053ef325b5dbcd104
ToppCell368C-Endothelial_cells-Endothelial-F_(Lymphatics)-|368C / Donor, Lineage, Cell class and subclass (all cells)

ITGA9 MMRN1 STOX2 SCNN1B NTN1

5.84e-051681095dae37b316ce80dfe4236c4ed7f0d4e7c340fa7b6
ToppCellfacs-Diaphragm-Limb_Muscle-24m|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LARS2 LRP1B OTOGL HYDIN DNAH11

6.01e-05169109512bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCell367C-Myeloid-Dendritic-pDC|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

SPAG4 IRF7 EMILIN1 STOX2 PTPRS

6.18e-051701095fbb7019c6fba87326702b51f6819ea1af5f3a9b7
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_acinar_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRSS1 PRSS2 CAMK1D LARS2 NTN1

6.71e-051731095c62e3ffed55bbb00dcaef6da0aab8446f3f55085
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_acinar_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRSS1 PRSS2 CAMK1D LARS2 NTN1

6.71e-051731095f612d4ea9ab8dcde475f4118bca3e49be786e7fa
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CD248 DTX1 ITGA9 PAPSS2 FRZB

6.89e-051741095c529f3674b784f872f4387ffdeb46aecb619976b
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_PRSS12|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

COL12A1 PAPSS2 PTPN3 OTOGL ANO3

6.89e-051741095ae363ce736fc8af439f3ad594d7bc2e344db80d4
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL12A1 DTX1 LRP1B HYDIN FCAMR

7.28e-051761095c6484334187f64cd00cd35e77d8ae436556b4260
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL12A1 CD248 EMILIN1 FRZB C22orf39

7.28e-051761095fcf324e6402819683f95e0dd94bf1f777c7f4c76
ToppCellControl-Neuronal_cells-Neuronal_cells|Control / group, cell type (main and fine annotations)

DTX1 ITGA9 MMRN1 STOX2 NTN1

7.28e-05176109598c07d26ba0dc0fe15ca0ea81f633d4591782bd1
ToppCell390C-Myeloid-Dendritic-pDC|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

PRPF8 LANCL2 NUDT12 PTPRS LY9

7.28e-051761095aab9603b7943b7f7243eb6190ebba998566196f3
ToppCellControl-Neuronal_cells|Control / group, cell type (main and fine annotations)

DTX1 ITGA9 MMRN1 STOX2 NTN1

7.28e-051761095c29d09ecf0eb17f767d78af4b7f2e7725c967ff8
ToppCell356C-Fibroblasts-Fibroblast-G|356C / Donor, Lineage, Cell class and subclass (all cells)

DELEC1 EMILIN1 PTPRD PTPRS FRZB

7.47e-0517710958220cc2fc0ee8764a67a3be51d75248be2453040
ToppCell356C-Fibroblasts-Fibroblast-G-|356C / Donor, Lineage, Cell class and subclass (all cells)

DELEC1 EMILIN1 PTPRD PTPRS FRZB

7.47e-0517710957617270f49cd6b7ba66db72d20560cee985012b2
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRSS2 PAPSS2 ABCA5 FRZB SCNN1B

7.68e-051781095fcbbcc44271515de1969b4732b6441c012693d5f
ToppCellAdult-Endothelial-endothelial_cell_of_lymph_vessel-D231|Adult / Lineage, Cell type, age group and donor

DTX1 ITGA9 MMRN1 STOX2 NTN1

7.68e-051781095c80ca7a2d3f976089a5e71d0cd9ba9a1c0bd2815
ToppCellAdult-Epithelial-club_cell-D122|Adult / Lineage, Cell type, age group and donor

ITGA9 LRP1B PTPRD SCNN1B NTN1

7.68e-05178109535a2e3ba98b6f857dbb79cf8ddb4846ddcda6c17
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

COL12A1 PAPSS2 PTPRD OTOGL ANO3

7.88e-0517910958766a5a066091879f521acfc612abf563ff78808
ToppCellPCW_10-12-Endothelial-Endothelial_mature-lymphatic|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

DTX1 MMRN1 FRZB SCNN1B ARRDC2

7.88e-051791095ab3d08b51cd7a37582305615ee221c7a2af83b40
ToppCellPCW_10-12-Endothelial-Endothelial_mature-lymphatic-endo_lymphatic_(7)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

DTX1 MMRN1 FRZB SCNN1B ARRDC2

7.88e-05179109535fe9961e228ce255e3317fc244efa35b5adbf8b
ToppCell5'-Airway_Nasal-Mesenchymal-Fibroblastic|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL12A1 CD248 EMILIN1 SULF1 MRC2

8.09e-051801095935c091bbcd6d10b81dc4731779e5bd98205c99f
ToppCell5'-Airway_Nasal-Mesenchymal|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL12A1 CD248 EMILIN1 SULF1 MRC2

8.09e-0518010953dd384b7f3d9582b8fec9fe05100e466e6218b76
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia/MHC-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GPR173 PTPRF PTPRS FRZB TNK2

8.09e-051801095e4add4c94f892a2d93926e5c6dac6a738319d091
ToppCellFetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

COL12A1 CD248 GPR173 ITGA9 MRC2

8.30e-051811095d7e04e0ca549eac6d9b1192b6578f9b54943d54f
ToppCellmetastatic_Brain-Fibroblasts-Myofibroblasts|metastatic_Brain / Location, Cell class and cell subclass

COL12A1 EMILIN1 PTPRD SULF1 MRC2

8.30e-051811095bd0b5f74f9c81ec0f1592710774a4fdf33d9d5a9
DrugTe Al

KDM5D FRZB RAC1 RAC3

2.08e-05351064CID000168005
Drug11-ethylthioundecanoic acid

NMT2 NMT1

2.15e-0521062CID000122099
DrugCRA_1144

PRSS1 HPN

2.15e-0521062DB03643
DrugClorgyline hydrochloride [17780-75-5]; Up 200; 13uM; MCF7; HT_HG-U133A

CAMK1D KLF6 MYOZ3 BIRC3 NF1 NTN1 NMT1

3.39e-0519310675005_UP
DrugN-benzoyl-L-tyrosine

PRSS1 PRSS2 FCAMR

4.28e-05151063CID000151021
DrugN-allylglycine

PRSS1 PRSS2

6.42e-0531062CID000076651
DrugN-acetyl-L-norvaline methyl ester

PRSS1 PRSS2

6.42e-0531062CID000150916
DrugYAKR-CK

PRSS1 PRSS2

6.42e-0531062CID005487256
Drug2 alpha-bromoacetoxyprogesterone

PRSS1 PRSS2

6.42e-0531062CID000135256
Drugmethyl lignocerate

PRSS1 PRSS2

6.42e-0531062CID000075546
DrugGB-107

PRSS1 PRSS2

6.42e-0531062CID000056813
Drugmitorubrinic acid

PRSS1 PRSS2

6.42e-0531062CID000379537
DrugASA-PE

PRSS1 PRSS2

6.42e-0531062CID003037809
Drugschizopeptin 791

PRSS1 PRSS2

6.42e-0531062CID000636821
DrugLapg-nh2

PRSS1 PRSS2

6.42e-0531062CID003082486
DrugMethotrexate-polylysine

PRSS1 PRSS2

6.42e-0531062CID000163214
Drugmethyl octanesulfonate

PRSS1 PRSS2

6.42e-0531062CID000165858
Drug3HFGB

PRSS1 PRSS2

6.42e-0531062CID000126268
Drug4-chlorobenzenediazonium hexafluorophosphate

PRSS1 PRSS2

6.42e-0531062CID002723983
Drug10-(carboxyethyl)flavin

PRSS1 PRSS2

6.42e-0531062CID003082170
DrugZ-Lys-CH2Cl

PRSS1 PRSS2

6.42e-0531062CID000127335
Drug2,6-dimethyl-3-pyridinol

PRSS1 PRSS2

6.42e-0531062CID000070732
DrugN-phosphopyridoxyl-L-serine

PRSS1 PRSS2

6.42e-0531062CID000195946
DrugZ-Arg-OH

PRSS1 PRSS2

6.42e-0531062CID000071055
Drugp-amidinophenylpyruvate

PRSS1 PRSS2

6.42e-0531062CID000444106
Drugv 1194

PRSS1 PRSS2

6.42e-0531062CID000074702
DrugL-TAPA

PRSS1 PRSS2

6.42e-0531062CID000193734
Drug4-MUNANA

DTX1 PTPRD CTPS1

1.23e-04211063CID000122202
DrugBvpam

PRSS1 PRSS2 KLK9

1.23e-04211063CID000125185
Drug4-Amino-3-nitrobenzoic acid

PRSS1 PRSS2

1.28e-0441062CID000074115
Drug4-ethylpiperidine

PRSS1 PRSS2

1.28e-0441062CID000076704
Drugtorquatone

PRSS1 PRSS2

1.28e-0441062CID000256516
DrugmGBSOM

PRSS1 PRSS2

1.28e-0441062CID003080804
DrugBa-O

PRSS1 PRSS2

1.28e-0441062CID000002280
Drug6-Chloro-2-(2-Hydroxy-Biphenyl-3-Yl)-1h-Indole-5-Carboxamidine

PRSS1 HPN

1.28e-0441062DB03865
DrugNSC-13568

PRSS1 PRSS2

1.28e-0441062CID000224783
Drugxylaric acid

PRSS1 PRSS2

1.28e-0441062CID003084064
DrugAC1LAOUV

PRSS1 PRSS2

1.28e-0441062CID000492408
Drug5'-S-propynyl-5'-thioadenosine

PRSS1 PRSS2

1.28e-0441062CID000492409
DrugAC1Q5JO7

PRSS1 PRSS2

1.28e-0441062CID000128324
DrugDsdgk

PRSS1 PRSS2

1.28e-0441062CID000130454
DrugNSC-45351

PRSS1 PRSS2

1.28e-0441062CID000018046
Drugindomethacin-NHS

PRSS1 PRSS2

1.28e-0441062CID000128571
Drugbromomesaconic acid

PRSS1 PRSS2

1.28e-0441062CID006449799
DrugN-carbobenzoxyglycine vinyl ester

PRSS1 PRSS2

1.28e-0441062CID000047309
DrugMnGTP

PRSS1 PRSS2 KDM5D

1.42e-04221063CID000160802
Druglead titanate zirconate

NTN1 RAC1

2.13e-0451062ctd:C065536
DrugSr 42128

PRSS1 PRSS2

2.13e-0451062CID005487043
Drug4-TGPAP

PRSS1 PRSS2

2.13e-0451062CID000132086
DrugPTA-Arg

PRSS1 PRSS2

2.13e-0451062CID000194378
DrugI 333

PRSS1 PRSS2

2.13e-0451062CID000533915
DrugN-(5'-carboxypentyl)-1-deoxynojirimycin

PRSS1 PRSS2

2.13e-0451062CID000133177
Drugpropynyl benzoate

PRSS1 PRSS2

2.13e-0451062CID000196666
DrugM 93

PRSS1 PRSS2

2.13e-0451062CID006444952
DrugAg-B

PRSS1 PRSS2

2.13e-0451062CID000004286
Drug2,6-diphenoxypyridine

PRSS1 PRSS2

2.13e-0451062CID000824772
DrugAC1L3UIZ

PRSS1 PRSS2

2.13e-0451062CID000147121
DrugIle-Phe-Lys-CH2Cl

PRSS1 PRSS2

2.13e-0451062CID000124393
Drugrho-guanidinobenzoate

PRSS1 PRSS2

2.13e-0451062CID005311472
DrugPTA-GPA

PRSS1 PRSS2

2.13e-0451062CID000139330
Drug6-amidinoindole

PRSS1 PRSS2

2.13e-0451062CID003018291
Drugbeta-Neuroprotectin

PRSS1 PRSS2

2.13e-0451062CID005748443
DrugN-myristoylGly

NMT2 NMT1

2.13e-0451062CID000072348
DrugMeebdp

PRSS1 PRSS2

2.13e-0451062CID000132560
Drugtrifluoroacetic acid

PRSS1 PRSS2 DTX1 LANCL2

2.27e-04641064CID000006422
Drugtriflate

PRSS1 PRSS2 DTX1 PTPRD

2.72e-04671064CID000062406
DrugChlorprothixene hydrochloride [6469-93-8]; Up 200; 11.4uM; MCF7; HT_HG-U133A

KLF6 KDM4C BIRC3 PTPRS SULF1 SCNN1B

2.74e-0419110662627_UP
DrugErgocryptine-alpha [511-09-1]; Up 200; 7uM; MCF7; HT_HG-U133A

TRPV1 ZBTB33 ITGA9 MRC2 NMT2 SCNN1B

2.98e-0419410663900_UP
DrugRemoxipride Hydrochloride [73220-03-8]; Up 200; 9.8uM; HL60; HT_HG-U133A

MYOZ3 PAPSS2 PTPRD NMT2 TNK2 IL27RA

3.06e-0419510663124_UP
DrugAg2SO4

PRSS1 PRSS2

3.18e-0461062CID000159275
DrugB258

RAC1 RAC3

3.18e-0461062CID000593690
DrugN-benzoyltyrosine butylamide

PRSS1 PRSS2

3.18e-0461062CID000125261
DrugCirculin A

PRSS1 PRSS2

3.18e-0461062CID000065155
DrugDb04336

PRSS1 PRSS2

3.18e-0461062CID000002014
DrugN-benzoyl-L-tyrosine thiobenzyl ester

PRSS1 PRSS2

3.18e-0461062CID000191444
DrugAC1O3UDU

CSF2RA FRZB

3.18e-0461062CID006337927
DrugN,N-dimethylglycylbenzocaine

PRSS1 PRSS2

3.18e-0461062CID000188251
Drug2 up

PRSS1 PRSS2

3.18e-0461062CID000193409
Drugazidobestatin

PRSS1 PRSS2

3.18e-0461062CID000132261
Drug2-azidoatrazine

PRSS1 PRSS2

3.18e-0461062CID003032432
Drug4-TAPAP

PRSS1 PRSS2

3.18e-0461062CID000133476
DrugVigabatrin [60643-86-9]; Down 200; 31uM; HL60; HT_HG-U133A

SPAG4 ZNF142 NF1 PTPRF PTPRS TNK2

3.24e-0419710662452_DN
DrugTodralazine hydrochloride [3778-76-5]; Down 200; 14.8uM; PC3; HT_HG-U133A

KDM5C ATXN3 HELZ MPC1 EPHA1 IL27RA

3.24e-0419710661799_DN
DrugC75; Up 200; 10uM; PC3; HT_HG-U133A

KLF6 KDM5D NF1 SULF1 MRC2 SCNN1B

3.24e-0419710666399_UP
DrugIdazoxan hydrochloride [79944-56-2]; Down 200; 16.6uM; HL60; HT_HG-U133A

TRPV1 ZNF671 BIRC3 PAPSS2 NMT2 TNK2

3.33e-0419810663088_DN
DrugNitrofurantoin [67-20-9]; Up 200; 16.8uM; MCF7; HT_HG-U133A

CAMK1D CD248 KDM4C KDM5D FRZB NMT1

3.33e-0419810664697_UP
Drug2-propylpentanoic acid; Up 200; 50uM; HL60; HT_HG-U133A

KDM4C PAPSS2 PIK3CG NMT2 TNK2 RAC3

3.33e-0419810661163_UP
Diseaseasthma, response to diisocyanate

COL12A1 KDM4C CLSTN1 LRP1B PTPN3 PTPRD HERC2 OTOG

4.17e-062611048EFO_0006995, MONDO_0004979
Diseasesyndromic intellectual disability (implicated_via_orthology)

KDM5C KDM5D PDZD8

2.30e-05161043DOID:0050888 (implicated_via_orthology)
Diseaseautosomal dominant intellectual developmental disorder 48 (implicated_via_orthology)

RAC1 RAC3

3.68e-0531042DOID:0080235 (implicated_via_orthology)
Diseasesyndromic X-linked intellectual disability Claes-Jensen type (implicated_via_orthology)

KDM5C KDM5D

7.35e-0541042DOID:0060809 (implicated_via_orthology)
DiseaseGlobal developmental delay

ZNF142 KDM5C GTF3C3 PRR12 RAC1

1.11e-041331045C0557874
Diseaseazoospermia (implicated_via_orthology)

PTPRD PTPRF PTPRS

1.17e-04271043DOID:14227 (implicated_via_orthology)
DiseasePANCREATITIS, HEREDITARY

PRSS1 PRSS2

1.22e-0451042167800
DiseaseHereditary pancreatitis

PRSS1 PRSS2

1.22e-0451042cv:C0238339
Diseasemuscular disease (implicated_via_orthology)

NMT2 NMT1

1.22e-0451042DOID:0080000 (implicated_via_orthology)
DiseaseAutosomal Dominant Hereditary Pancreatitis

PRSS1 PRSS2

1.22e-0451042C4080064
DiseaseIntellectual Disability

ZNF142 KDM5C GTF3C3 PRR12 EEF1B2 NF1 RAC1 RAC3

1.89e-044471048C3714756
Diseasepost-traumatic stress disorder symptom measurement

PTPRD SULF1 PIK3CG RAC1

2.06e-04821044EFO_0008535
DiseaseHereditary pancreatitis

PRSS1 PRSS2

2.55e-0471042C0238339
Diseasekidney disease (implicated_via_orthology)

UMOD RAC1 RAC3

4.11e-04411043DOID:557 (implicated_via_orthology)
DiseasePancreatitis, Chronic

PRSS1 PRSS2

4.36e-0491042C0149521
Diseaseautistic disorder (is_implicated_in)

KDM4C NF1 PIK3CG

4.42e-04421043DOID:12849 (is_implicated_in)
Diseaseoccupational attainment

CD248 PTPRF SYT4

4.42e-04421043EFO_0020977
Diseasealcohol use disorder (implicated_via_orthology)

KDM4C KDM5C KDM5D RAC1 RAC3

6.49e-041951045DOID:1574 (implicated_via_orthology)
Diseaseepilepsy, response to xenobiotic stimulus

ADAM29 PTPRD

6.63e-04111042EFO_0000474, GO_0009410
Diseasegallbladder carcinoma (is_marker_for)

BIRC3 RAC1

7.94e-04121042DOID:4948 (is_marker_for)
DiseaseColorectal Carcinoma

PRSS1 CD248 ADAM29 NF1 PTPRD ABCA5 PTPRS SCNN1B EPHA1

8.55e-047021049C0009402
Diseasecolon cancer (is_marker_for)

KDM5C BIRC3 NF1

1.20e-03591043DOID:219 (is_marker_for)
DiseaseOpioid use measurement

PTPRD MYOM2

1.25e-03151042EFO_0009937
Diseasewaist-hip ratio

KLF6 DTX1 DELEC1 ITGA9 ADAMTS10 EEF1B2 PTPRD PTPRS POC1B PDZD8 SYT4 ANO3

1.28e-03122610412EFO_0004343
Diseaseresponse to radiation, Urinary retention

LRP1B PTPRS

1.62e-03171042GO_0009314, HP_0000016
Diseaseischemia (implicated_via_orthology)

ITGAV SCNN1B

1.62e-03171042DOID:326 (implicated_via_orthology)
Diseaseattention deficit hyperactivity disorder, Cannabis use

PTPRF POC1B

1.81e-03181042EFO_0003888, EFO_0007585
Diseasemelanoma

KDM4C LRP1B NF1 SYT4 RAC1

1.88e-032481045C0025202
Diseaseunipolar depression, response to bupropion, mood disorder

DELEC1 STOX2

2.02e-03191042EFO_0003761, EFO_0004247, EFO_0006326
Diseaseintellectual disability (implicated_via_orthology)

KDM5C KDM5D ITGAV

2.39e-03751043DOID:1059 (implicated_via_orthology)
Diseaseinterleukin-2 receptor subunit alpha measurement

KLF6 NTN1

2.47e-03211042EFO_0010587
DiseaseHIV-1 infection, Susceptibility to viral and mycobacterial infections

KDM4C FRMPD1

2.47e-03211042EFO_0000180, Orphanet_391311
Diseasefumarate measurement

ITGA9 LARS2

2.47e-03211042EFO_0010480
Diseasepulmonary function measurement

PTPRD PDZD8 ARRDC2

2.58e-03771043EFO_0003892
Diseasecolorectal carcinoma (is_implicated_in)

BIRC3 RAC1

2.71e-03221042DOID:0080199 (is_implicated_in)
DiseaseBronchiectasis

SCNN1B DNAH11

2.71e-03221042C0006267
Diseasecomplement factor H-related protein 3 measurement

COL12A1 CFHR5 SYT4 RAC1

3.06e-031691044EFO_0600056

Protein segments in the cluster

PeptideGeneStartEntry
DPCSRHIVWNLLKYR

ABCA5

646

Q8WWZ7
VHLYCKWKSENITPR

ADAM29

266

Q9UKF5
YVHGERPACEQWQRD

C22orf39

71

Q6P5X5
NCWAYDRARRPHFQK

EPHA1

861

P21709
QFPAVHRWKSAVLCY

ANKLE2

851

Q86XL3
HRWKSAVLCYSPSDR

ANKLE2

856

Q86XL3
HRRWRTEYAIKCAPC

ANKK1

41

Q8NFD2
HAPNKRITDCYRWVI

CD248

716

Q9HCU0
RQYRQELVHCKWVPF

DNAH11

3426

Q96DT5
QHAKWFPRCEYLIRI

BIRC3

311

Q13489
YRPAEFHWKLNQVCD

CLSTN1

441

O94985
SVRYCIKATLHRPWV

ARRDC2

126

Q8TBH0
GLAWQRAARPHCLYA

ADAMTS10

111

Q9H324
CHGWSVQRAAQYLKV

TNK2

981

Q07912
HIPWDTLCKYAERLN

ANO3

211

Q9BYT9
YKVQPRNWLLFACHA

MPC1

71

Q9Y5U8
DRCKPFHYDRPWQRA

NTN1

316

O95631
ENVRAKWYPEVRHHC

RAC3

91

P60763
ENVRAKWYPEVRHHC

RAC1

91

P63000
AAQPWHSCHKLIYVR

INTS6L

261

Q5JSJ4
YILERKSPHTCWQVF

INTS6L

341

Q5JSJ4
LTERGRTKCHQYWPD

PTPN3

746

P26045
RDAIYHCREQPASDW

ANAPC1

956

Q9H1A4
LYAGPTEVQWHCRSR

PAPSS2

486

O95340
QCLAAHPVRGKLYWT

LRP1B

1696

Q9NZR2
FVKDPNTRWDYCVRA

KIAA0895

411

Q8NCT3
VGTCRYWHRSLNPRK

NMT1

291

P30419
CRYWHRSLNPRKLVE

NMT2

296

O60551
RHFNIHSWEKKYPCR

ZBTB33

511

Q86T24
SPNRLVYREQHRSWC

HERC2

2011

O95714
RGKNWCAYVHTRLSP

MMRN1

206

Q13201
PINERSFICNYKEHW

ATXN3

106

P54252
DWLPAGRQCIEHYRR

KDM5D

611

Q9BY66
EERKTERCPLLYQWH

LANCL2

241

Q9NS86
ACHRYLNIALWCRDP

PDZD8

706

Q8NEN9
VSKSVCAEPWRHQRA

FAM157C

316

P0CG43
WPSHKVLICQFHYRR

IL27RA

156

Q6UWB1
DDWPYVVNITCFRHK

KDM4C

851

Q9H3R0
GHCYRLQAEKRSWQE

MRC2

391

Q9UBG0
ARTCFRVPWKHFARK

IRF7

36

Q92985
YRHTHWVRCAKFSPD

POC1B

141

Q8TC44
VKEALRQTWSRFHCP

OR5C1

301

Q8NGR4
NRWVKTVHPVVHQYC

HELZ

731

P42694
RWRPYTATVCHHIEN

DTX1

36

Q86Y01
DWVLTAAHCFPERNR

HPN

196

P05981
GREKCHQYWPAERSA

PTPRS

1786

Q13332
CRYVLHVVAPEWRNG

PARP14

1086

Q460N5
DGRVLACAHRWKNIY

ITGA9

136

Q13797
PSSVNRHQRKYWCRL

FCAMR

86

Q8WWV6
CEQHVDYKRPSWTKE

HYDIN

616

Q4G0P3
PHVRDCIRSYTEDWA

DOCK7

111

Q96N67
CVKWSPHRAATSYRL

COL12A1

2221

Q99715
HRERSVKWQAGVCYN

DELEC1

36

Q9P2X7
KSHIWPEYCSRALRQ

FRMPD1

1396

Q5SYB0
KQDKILACAPLYHWR

ITGAV

131

P06756
RLTFPCASEYLWHAR

CFAP97D2

6

A0A1B0GU71
DIFRYRHSVCINGKW

CFHR5

361

Q9BXR6
CYWRVFVKACAVPHR

GPR173

306

Q9NS66
RDPYKNRVWVSSQDC

LY9

306

Q9HBG7
AAHCRKPYLWVRLGE

KLK9

61

Q9UKQ9
RPASRHRNWCAYVVT

EMILIN1

51

Q9Y6C2
PADLCHALRWYNHIK

EEF1B2

46

P24534
LVWYCDNTNTHGPKR

SCNN1B

26

P51168
THCLVRWKQPRTYQK

CSF2RA

231

P15509
ARACSHAGYPIQDWR

OTOGL

366

Q3ZCN5
REKCHQYWPAERSAR

PTPRF

1746

P10586
REKCHQYWPAERSAR

PTPRD

1751

P23468
SWERRLHRAKCAPSY

OTOG

96

Q6ZRI0
KFHVCIEWRRSDYCP

OTOG

2356

Q6ZRI0
KEICDYPRRQIAKWH

SYT4

406

Q9H2B2
WKQRHSRSRPYPVCF

TCEAL8

101

Q8IYN2
VPRKLCAHYTWDASV

LARS2

806

Q15031
AHALRRILYSTWCPA

SH2D5

86

Q6ZV89
PVRYHEAWQKLCSAH

CTPS1

351

P17812
ARSVLAWHSRYKFCP

NUDT12

271

Q9BQG2
KDYVRVCARKPWHRP

PRR12

1656

Q9ULL5
IRYPNWKHISCKHAE

RWDD2A

211

Q9UIY3
NWGHPRFTCLYRVRA

SPAG4

406

Q9NPE6
KRYTCEQAARHPWIA

CAMK1D

266

Q8IU85
ERYNLAVVWLRHAEC

GTF3C3

451

Q9Y5Q9
CLRYWKATHRSPGQI

PIK3CG

121

P48736
ALDIPLVKNWYREHC

PRPF8

421

Q6P2Q9
AYITWAEKHPQCQRL

PLEKHG5

461

O94827
HWRVHTKERPYECNE

ZNF132

561

P52740
NRHQWTHSEEKPYVC

ZNF343

341

Q6P1L6
RHWKVHTGERPYVCS

ZNF671

496

Q8TAW3
RWDAAYLPAVAAVCV

TYMSOS

21

Q8TAI1
RAEWERTCGPYHKQR

MRPL38

136

Q96DV4
ADPCQAHRTLDEYWR

UMOD

171

P07911
HGEKLRRNCTIYRPW

SPATA46

81

Q5T0L3
PECRHLSRKFTEWAY

TRPV1

361

Q8NER1
RQGCEPILIKYRHSW

FRZB

116

Q92765
KWYHLDERIPDRSQC

STOX2

156

Q9P2F5
RCKPISGHNSLFWYR

TRBV12-3

41

P01733
WPKIDAVYCHSVELR

NF1

426

P21359
LEKCQIPRSHCWVYD

SRRD

166

Q9UH36
HSYWICKPAELSRGR

TTLL2

206

Q9BWV7
QWVVSAGHCYKSRIQ

PRSS2

56

P07478
QHILWPKRADCTESY

TTC17

496

Q96AE7
CPRVFNNRWYLEKHM

ZBTB47

441

Q9UFB7
KHWRVHTGERPYKCN

ZNF792

411

Q3KQV3
VKHWRNHTGERPYKC

ZNF548

381

Q8NEK5
KPYVCNVCHRAFRWA

ZNF142

1591

P52746
QWVVSAGHCYKSRIQ

PRSS1

56

P07477
QRLPKYYSWERCSKH

ZNF674

141

Q2M3X9
IHCERELYQSARAWK

SULF1

626

Q8IWU6
RDPELNWQAYCTRAK

TTC22

326

Q5TAA0
NWQAYCTRAKIHIRA

TTC22

331

Q5TAA0
WRCQLQKATRHHPSY

PRRG3

101

Q9BZD7
QVHWRFHTGEKPYRC

ZNF285

416

Q96NJ3
QRTHTGEKPYRCSWE

KLF6

221

Q99612
DWLPAGRQCIEHYRR

KDM5C

621

P41229
CHDANRDYVIVTWKP

MYOM2

391

P54296
NHTAISKGYRCPWQE

MYOZ3

156

Q8TDC0