Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	Schwann cell development	RAF1 NTRK2 PLEC PARD3 SOS1	1.19e-05	47	131	5	GO:0014044
GeneOntologyBiologicalProcess	Schwann cell differentiation	RAF1 NTRK2 PLEC PARD3 SOS1	2.58e-05	55	131	5	GO:0014037
GeneOntologyCellularComponent	peroxisomal importomer complex	PEX12 PEX14	1.24e-04	3	135	2	GO:1990429
Domain	CH	MICAL1 ARHGEF7 SYNE2 PLEC ARHGEF6	8.94e-05	65	130	5	SM00033
Domain	-	DOCK10 PTPN21 SYNGAP1 ARHGEF7 PLEKHA3 AKAP13 TNS1 ARHGEF6 TNS3 DCP1A SOS1	9.22e-05	391	130	11	2.30.29.30
Domain	CH	MICAL1 ARHGEF7 SYNE2 PLEC ARHGEF6	1.27e-04	70	130	5	PF00307
Domain	-	MICAL1 ARHGEF7 SYNE2 PLEC ARHGEF6	1.36e-04	71	130	5	1.10.418.10
Domain	CH	MICAL1 ARHGEF7 SYNE2 PLEC ARHGEF6	1.56e-04	73	130	5	PS50021
Domain	CH-domain	MICAL1 ARHGEF7 SYNE2 PLEC ARHGEF6	1.77e-04	75	130	5	IPR001715
Domain	PH_dom-like	DOCK10 PTPN21 SYNGAP1 ARHGEF7 PLEKHA3 AKAP13 TNS1 ARHGEF6 TNS3 DCP1A SOS1	1.95e-04	426	130	11	IPR011993
Domain	Tensin_PTB	TNS1 TNS3	2.86e-04	4	130	2	IPR033929
Domain	Helical_ferredxn	ETFDH CDON	4.74e-04	5	130	2	IPR009051
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	RAF1 MAGI1 ARHGAP32 SHROOM3 CEP162 TBC1D5 NCKIPSD BRSK2 PTPN21 INPP5F ZCCHC14 MTUS1 KIAA1217 PLEKHA3 SYNE2 AKAP13 PLEC PARD3 ZNF598 PC TNS3 DCP1A	3.15e-12	861	136	22	36931259
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	PRUNE2 RAF1 ARHGAP32 SHROOM3 ANK3 TBC1D5 PEX14 SYNGAP1 AKAP13 PLEC ZHX1 FHIP1A SOS1 MGRN1	1.71e-09	430	136	14	35044719
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	SHROOM3 KIF26A CEP162 SMPD4 HIC2 SFI1 INPP5F GPR107 MTUS1 RBM27 ARHGEF7 MRC2 CACNA1G MGRN1	2.33e-08	529	136	14	14621295
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	HMBOX1 PRUNE2 MAGI1 SHROOM3 ANK3 TBC1D5 KAT6A PEX14 CHD9 TTC3 C2CD2 RLF KIDINS220 FAM120C KIAA1217 FOXP1 AKAP13 PNPLA7 PARD3 NLK PDZD2 MGRN1	8.02e-08	1489	136	22	28611215
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	MAGI1 ARHGAP32 SHROOM3 ANK3 NTRK2 TBC1D5 ZNFX1 ZNF318 TTC3 SYNGAP1 KCNA4 FAM120C ARHGEF7 KIAA1217 SYNE2 PARD3 TNS1	2.43e-07	963	136	17	28671696
Pubmed	Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry.	TBC1D5 CD5 ARHGEF7 PDE8B POC5 PARD3 ARHGEF6	9.88e-07	133	136	7	15144186
Pubmed	The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.	RAF1 MAGI1 ARHGAP32 TBC1D5 SMPD4 SLC39A10 PARP14 GPR107 KIDINS220 SLC15A1 PARD3 TNS3	2.64e-06	569	136	12	30639242
Pubmed	Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	KIF26A SLC39A10 PARP14 KIDINS220 MTUS1 KIAA1217	3.35e-06	103	136	6	10574462
Pubmed	A human MAP kinase interactome.	MAGI1 ARHGAP32 ANK3 KIF26A ARHGEF7 CEP250 AKAP13 PLEC TNS1 ZHX1 SOS1	3.60e-06	486	136	11	20936779
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	ARHGAP32 PLOD3 ANK3 CEP162 TBC1D5 SMPD4 PTPN21 SLC39A10 MTUS1 SSH3 SYNE2 POC5 PC TNS1 TNS3 DCP1A	3.71e-06	1049	136	16	27880917
Pubmed	Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.	FAM193B PCNX3 PKD1L1 HIC2 INPP5F TTC3 RSC1A1 SYNGAP1 ZCCHC14 TIA1 SHARPIN ADAMTS20 B4GALNT3 PC ZHX1 DCP1A MGRN1	5.67e-06	1215	136	17	15146197
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	RAF1 ZDBF2 ZNF318 INPP5F RLF FOXP1 PLEC PC DCP1A TANGO6	6.25e-06	418	136	10	34709266
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	ARHGAP32 SHROOM3 CEP162 TBC1D5 PKD1L1 CCDC66 MTUS1 KIAA1217 CEP250 POC5 PLEC ZNF598 PC FHIP1A	6.87e-06	853	136	14	28718761
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	FAM193B SHROOM3 PLOD3 PCNX3 KIF26A KAT6A SFI1 TTC3 C2CD2 ADCY7 ZCCHC14 CHST15 AKAP13 PLEC PC ULK2	7.13e-06	1105	136	16	35748872
Pubmed	Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization.	NCKIPSD SRPK1 ARHGEF7 CEP250 AKAP13 PARD3 ARHGEF6 DCP1A	7.85e-06	255	136	8	15324660
Pubmed	Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.	HMBOX1 SHROOM3 NRBF2 PEX14 REST CSRNP3 KIAA1217 FOXP1 PARD3 FUT8 SOS1	9.05e-06	536	136	11	15840001
Pubmed	Exchangeable gene trap using the Cre/mutated lox system.	HMBOX1 SHROOM3 NRBF2 PEX14 REST CSRNP3 KIAA1217 FOXP1 PARD3 FUT8 SOS1	9.37e-06	538	136	11	10512203
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	SHROOM3 ANK3 CEP162 PEX14 ZNF318 SLC39A10 CASP12 CD5 KIDINS220 HCFC2 PARD3 PC CDON	1.22e-05	777	136	13	35844135
Pubmed	Tumor spectrum in children with Noonan syndrome and SOS1 or RAF1 mutations.	RAF1 SOS1	1.52e-05	2	136	2	19953625
Pubmed	A kinome screen reveals that Nemo-like kinase is a key suppressor of hepatic gluconeogenesis.	SHROOM3 NLK	1.52e-05	2	136	2	33951476
Pubmed	Tensin Regulates Fundamental Biological Processes by Interacting with Integrins of Tonsil-Derived Mesenchymal Stem Cells.	TNS1 TNS3	1.52e-05	2	136	2	35954177
Pubmed	Characterization of HRG22, a human homologue of the putative tumor suppressor gene HIC1.	HIC1 HIC2	1.52e-05	2	136	2	11554746
Pubmed	A Dynamic Splicing Program Ensures Proper Synaptic Connections in the Developing Cerebellum.	CDC7 SYNGAP1 TIA1 CACNA1G	2.69e-05	44	136	4	32492419
Pubmed	Cullin 1 (CUL1) Promotes Primary Ciliogenesis through the Induction of Ubiquitin-Proteasome-Dependent Dvl2 Degradation.	RAF1 ZNFX1 REST EML5 PLEC PC	3.11e-05	152	136	6	34299191
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	PRUNE2 DOCK10 HIC2 ZBTB24 ZCCHC14 SYNE2 CACNA1G	3.11e-05	225	136	7	12168954
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	DOCK10 SLC39A10 ZCCHC14 UNC5A KIDINS220 CHST15 ZNF319 ULK2 PDZD2	3.41e-05	407	136	9	12693553
Pubmed	BNIP2 extra long inhibits RhoA and cellular transformation by Lbc RhoGEF via its BCH domain.	PRUNE2 AKAP13	4.54e-05	3	136	2	18445682
Pubmed	Novel interactions of ankyrins-G at the costameres: the muscle-specific Obscurin/Titin-Binding-related Domain (OTBD) binds plectin and filamin C.	ANK3 PLEC	4.54e-05	3	136	2	21223964
Pubmed	Allosteric gating of Son of sevenless activity by the histone domain.	RAF1 SOS1	4.54e-05	3	136	2	20133694
Pubmed	Decreased expression of FGFR1, SOS1, RAF1 genes in cryptorchidism.	RAF1 SOS1	4.54e-05	3	136	2	20389169
Pubmed	Targeted proteomic analysis of 14-3-3 sigma, a p53 effector commonly silenced in cancer.	RAF1 MAGI1 ARHGAP32 SHROOM3 PARD3	5.22e-05	102	136	5	15778465
Pubmed	Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.	BRSK2 SLC30A3 SYNGAP1 KCNA4 ARHGEF7 PLEC NLK SOS1	7.04e-05	347	136	8	17114649
Pubmed	RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.	ARHGAP32 ANK3 SMPD4 ZNF318 KIDINS220 KIAA1217 PARD3	8.31e-05	263	136	7	34702444
Pubmed	Tensin3 is a negative regulator of cell migration and all four Tensin family members are downregulated in human kidney cancer.	TNS1 TNS3	9.06e-05	4	136	2	19194507
Pubmed	A novel group of spindle cell tumors defined by S100 and CD34 co-expression shows recurrent fusions involving RAF1, BRAF, and NTRK1/2 genes.	RAF1 NTRK2	9.06e-05	4	136	2	30276917
Pubmed	Cardiac features of Noonan syndrome in Japanese patients.	RAF1 SOS1	9.06e-05	4	136	2	35475426
Pubmed	PAK kinases are directly coupled to the PIX family of nucleotide exchange factors.	ARHGEF7 ARHGEF6	9.06e-05	4	136	2	9659915
Pubmed	Novel regulatory mechanisms for the Dbl family guanine nucleotide exchange factor Cool-2/alpha-Pix.	ARHGEF7 ARHGEF6	9.06e-05	4	136	2	15306850
Pubmed	A tyrosine-phosphorylated protein that binds to an important regulatory region on the cool family of p21-activated kinase-binding proteins.	ARHGEF7 ARHGEF6	9.06e-05	4	136	2	10428811
Pubmed	The language phenotype of children and adolescents with Noonan syndrome.	RAF1 SOS1	9.06e-05	4	136	2	20543023
Pubmed	Human homologue of Drosophila CNK interacts with Ras effector proteins Raf and Rlf.	RAF1 RLF	9.06e-05	4	136	2	14597674
Pubmed	The Cool-2/alpha-Pix protein mediates a Cdc42-Rac signaling cascade.	ARHGEF7 ARHGEF6	9.06e-05	4	136	2	15649357
Pubmed	Signaling to cardiac hypertrophy: insights from human and mouse RASopathies.	RAF1 SOS1	9.06e-05	4	136	2	22576369
Pubmed	The human candidate tumor suppressor gene HIC1 recruits CtBP through a degenerate GLDLSKK motif.	HIC1 HIC2	9.06e-05	4	136	2	12052894
Pubmed	Expanding functions of GIT Arf GTPase-activating proteins, PIX Rho guanine nucleotide exchange factors and GIT-PIX complexes.	ARHGEF7 ARHGEF6	9.06e-05	4	136	2	27182061
Pubmed	Interaction of alphaPIX (ARHGEF6) with beta-parvin (PARVB) suggests an involvement of alphaPIX in integrin-mediated signaling.	ARHGEF7 ARHGEF6	9.06e-05	4	136	2	12499396
Pubmed	The Cbl proteins are binding partners for the Cool/Pix family of p21-activated kinase-binding proteins.	ARHGEF7 ARHGEF6	9.06e-05	4	136	2	12935897
Pubmed	PTPN11, SOS1, KRAS, and RAF1 gene analysis, and genotype-phenotype correlation in Korean patients with Noonan syndrome.	RAF1 SOS1	9.06e-05	4	136	2	19020799
Pubmed	PEX12 interacts with PEX5 and PEX10 and acts downstream of receptor docking in peroxisomal matrix protein import.	PEX12 PEX14	9.06e-05	4	136	2	10562279
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	ANK3 CEP162 ZNF318 SLC39A10 TTC3 ZBTB24 EML5 TIA1 PLEC PARD3 TNS1 ULK2 ARHGEF6 DCP1A	9.39e-05	1084	136	14	11544199
Pubmed	A meta-analysis of 87,040 individuals identifies 23 new susceptibility loci for prostate cancer.	PEX14 HTR3B TNS3	9.78e-05	23	136	3	25217961
Pubmed	POH1 contributes to hyperactivation of TGF-β signaling and facilitates hepatocellular carcinoma metastasis through deubiquitinating TGF-β receptors and caveolin-1.	MAGI1 FLG SHROOM3 SYNE2 PLEC ULK2 SOS1	1.15e-04	277	136	7	30745168
Pubmed	Inactivation of tensin3 in mice results in growth retardation and postnatal lethality.	TNS1 TNS3	1.51e-04	5	136	2	15733665
Pubmed	Molecular anatomy of the peroxin Pex12p: ring finger domain is essential for Pex12p function and interacts with the peroxisome-targeting signal type 1-receptor Pex5p and a ring peroxin, Pex10p.	PEX12 PEX14	1.51e-04	5	136	2	10837480
Pubmed	The phosphotyrosine-independent interaction of DLC-1 and the SH2 domain of cten regulates focal adhesion localization and growth suppression activity of DLC-1.	TNS1 TNS3	1.51e-04	5	136	2	17190795
Pubmed	A unique pathway for sustained neurotrophin signaling through an ankyrin-rich membrane-spanning protein.	NTRK2 KIDINS220	1.51e-04	5	136	2	15167895
Pubmed	Paxillin-dependent paxillin kinase linker and p21-activated kinase localization to focal adhesions involves a multistep activation pathway.	ARHGEF7 ARHGEF6	1.51e-04	5	136	2	12006652
Pubmed	The p21-activated kinase PAK is negatively regulated by POPX1 and POPX2, a pair of serine/threonine phosphatases of the PP2C family.	ARHGEF7 ARHGEF6	1.51e-04	5	136	2	11864573
Pubmed	Substrate trapping proteomics reveals targets of the βTrCP2/FBXW11 ubiquitin ligase.	MAGI1 FOXN2 REST EML5 PLEC	1.53e-04	128	136	5	25332235
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	ARHGAP32 HSP90B2P ANK3 NTRK2 BRSK2 ZNFX1 ZDBF2 SYNGAP1 KCNA4 FAM120C ARHGEF7 KIAA1217 PLEC PC	1.57e-04	1139	136	14	36417873
Pubmed	Voltage-dependent conformational changes of Kv1.3 channels activate cell proliferation.	RAF1 HSP90B2P DOCK10 CHD9 CDC7 KIDINS220	1.75e-04	208	136	6	33230847
Pubmed	Local anesthetics impair the growth and self-renewal of glioblastoma stem cells by inhibiting ZDHHC15-mediated GP130 palmitoylation.	SHROOM3 ZNF318 TTC3 KIAA1217	1.77e-04	71	136	4	33541421
Pubmed	Interactomes of Glycogen Synthase Kinase-3 Isoforms.	FAM193B ZDBF2 KIDINS220 MTUS1 TNS3 DCP1A	1.80e-04	209	136	6	36779422
Pubmed	Gene-trap mutagenesis using Mol/MSM-1 embryonic stem cells from MSM/Ms mice.	HMBOX1 CSRNP3 KIAA1217 FOXP1	2.08e-04	74	136	4	23604909
Pubmed	Mapping the interactome of HPV E6 and E7 oncoproteins with the ubiquitin-proteasome system.	MAGI1 ASB4 MPND ZNF598 MGRN1	2.17e-04	138	136	5	28786561
Pubmed	Six post-implantation lethal knockouts of genes for lipophilic MAPK pathway proteins are expressed in preimplantation mouse embryos and trophoblast stem cells.	RAF1 SOS1	2.25e-04	6	136	2	15736129
Pubmed	Two forms of human Inscuteable-related protein that links Par3 to the Pins homologues LGN and AGS3.	F2RL2 PARD3	2.25e-04	6	136	2	16458856
Pubmed	Regulation of SPIN90 phosphorylation and interaction with Nck by ERK and cell adhesion.	NCKIPSD ARHGEF7	2.25e-04	6	136	2	14559906
Pubmed	Degree of predicted minor histocompatibility antigen mismatch correlates with poorer clinical outcomes in nonmyeloablative allogeneic hematopoietic cell transplantation.	MYO1G AKAP13	2.25e-04	6	136	2	20353833
Pubmed	Role of Unc51.1 and its binding partners in CNS axon outgrowth.	SYNGAP1 ULK2	2.25e-04	6	136	2	15014045
Pubmed	The junctional adhesion molecule (JAM) family members JAM-2 and JAM-3 associate with the cell polarity protein PAR-3: a possible role for JAMs in endothelial cell polarity.	F2RL2 PARD3	2.25e-04	6	136	2	12953056
Pubmed	Kidins220/ARMS mediates the integration of the neurotrophin and VEGF pathways in the vascular and nervous systems.	NTRK2 KIDINS220	2.25e-04	6	136	2	22048155
Pubmed	TorsinA binds the KASH domain of nesprins and participates in linkage between nuclear envelope and cytoskeleton.	SYNE2 PLEC	2.25e-04	6	136	2	18827015
Pubmed	Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism.	CEP162 SMARCAL1 PEX12 CHD9 HIC2 REST TTC3 CCDC66 SSH3 SHARPIN ZNF598 MGRN1	2.90e-04	925	136	12	28986522
Pubmed	Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant.	MAGI1 ARHGAP32 KCNA4 FAM120C ARHGEF7 CEP250 PARD3 PC	3.04e-04	430	136	8	32581705
Pubmed	Temporal patterning of apical progenitors and their daughter neurons in the developing neocortex.	ANK3 NTRK2 FOXP1 CDON	3.09e-04	82	136	4	31073041
Pubmed	EGFR phosphorylates FAM129B to promote Ras activation.	RAF1 SOS1	3.15e-04	7	136	2	26721396
Pubmed	The X-linked lymphoproliferative disease gene product SAP associates with PAK-interacting exchange factor and participates in T cell activation.	ARHGEF7 ARHGEF6	3.15e-04	7	136	2	16983070
Pubmed	The GIT family of ADP-ribosylation factor GTPase-activating proteins. Functional diversity of GIT2 through alternative splicing.	ARHGEF7 ARHGEF6	3.15e-04	7	136	2	10896954
Pubmed	Germline BRAF mutations in Noonan, LEOPARD, and cardiofaciocutaneous syndromes: molecular diversity and associated phenotypic spectrum.	RAF1 SOS1	3.15e-04	7	136	2	19206169
Pubmed	N-α-acetyltransferase 10 protein suppresses cancer cell metastasis by binding PIX proteins and inhibiting Cdc42/Rac1 activity.	ARHGEF7 ARHGEF6	3.15e-04	7	136	2	21295525
Pubmed	Investigation of gene dosage imbalances in patients with Noonan syndrome using multiplex ligation-dependent probe amplification analysis.	RAF1 SOS1	3.15e-04	7	136	2	20302979
Pubmed	Nucleotide exchange factor ECT2 interacts with the polarity protein complex Par6/Par3/protein kinase Czeta (PKCzeta) and regulates PKCzeta activity.	F2RL2 PARD3	3.15e-04	7	136	2	15254234
Pubmed	Cognitive profile of disorders associated with dysregulation of the RAS/MAPK signaling cascade.	RAF1 SOS1	3.15e-04	7	136	2	19133693
Pubmed	USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.	SRPK1 SLC15A1 FAM120C CEP250 PLEC PC	3.30e-04	234	136	6	36243803
Pubmed	Host PDZ-containing proteins targeted by SARS-CoV-2.	MAGI1 PARD3 PDZD2	3.49e-04	35	136	3	33864728
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	RAF1 MAGI1 SHROOM3 CEP162 TBC1D5 NCKIPSD INPP5F PARD3	3.87e-04	446	136	8	24255178
Pubmed	E-cadherin interactome complexity and robustness resolved by quantitative proteomics.	MAGI1 ARHGAP32 SHROOM3 ANK3 KIDINS220 SSH3 KIAA1217 PLEC PARD3	3.99e-04	565	136	9	25468996
Pubmed	Toxic gain of function from mutant FUS protein is crucial to trigger cell autonomous motor neuron loss.	FAM193B TTC3 SSH3	4.12e-04	37	136	3	26951610
Pubmed	Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis.	SCFD2 TBC1D5 SMPD4 PEX14 ZDBF2 C2CD2 RBM27 SYNE2 PRR14L	4.15e-04	568	136	9	37774976
Pubmed	ATM functions at the peroxisome to induce pexophagy in response to ROS.	PEX12 PEX14	4.19e-04	8	136	2	26344566
Pubmed	The PARP superfamily.	PARP14 TIPARP	4.19e-04	8	136	2	15273990
Pubmed	Affixin activates Rac1 via betaPIX in C2C12 myoblast.	ARHGEF7 ARHGEF6	4.19e-04	8	136	2	18325335
Pubmed	Aurora kinase A regulates Survivin stability through targeting FBXL7 in gastric cancer drug resistance and prognosis.	SOX30 REST FOXP1	4.46e-04	38	136	3	28218735
Pubmed	Mutation of ARHGAP9 in patients with coronary spastic angina.	AKAP13 ARHGEF6 SOS1	4.46e-04	38	136	3	19911011
Pubmed	Activation of Rac GTPase by p75 is necessary for c-jun N-terminal kinase-mediated apoptosis.	AKAP13 ARHGEF6 SOS1	4.46e-04	38	136	3	11756498
Pubmed	Proteomic and Biochemical Comparison of the Cellular Interaction Partners of Human VPS33A and VPS33B.	ARHGAP32 NRBF2 ANK3 SRPK1 RBM27 SYNE2	4.79e-04	251	136	6	29778605
Pubmed	Tissue-Specific Actions of Pax6 on Proliferation and Differentiation Balance in Developing Forebrain Are Foxg1 Dependent.	SLC30A3 KIAA1217 CDON	4.82e-04	39	136	3	30529950
Pubmed	Human transcription factor protein interaction networks.	HMBOX1 FLG ARHGAP32 HIC2 ZNF318 RLF CASP12 RBM27 SYNE2 FOXP1 HCFC2 ZNF319 ZHX1 DCP1A TANGO6	4.90e-04	1429	136	15	35140242
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	RAF1 MICAL1 ARHGAP32 HSP90B2P ANK3 NCKIPSD BRSK2 ZNFX1 SYNGAP1 KIDINS220 FAM120C KIAA1217 PLEC PC TNS1	4.98e-04	1431	136	15	37142655
Interaction	NCK2 interactions	MICAL1 ARHGAP32 NTRK2 NCKIPSD SRPK1 ANKRD55 SYNGAP1 ARHGEF7 SSH3 KIAA1217 SYNE2 ARHGEF6 SOS1	1.53e-08	262	130	13	int:NCK2
Interaction	YWHAH interactions	RAF1 MAGI1 ARHGAP32 SHROOM3 CEP162 TBC1D5 NCKIPSD PTPN21 INPP5F ANKRD55 SYNGAP1 ZCCHC14 MTUS1 ARHGEF7 KIAA1217 PLEKHA3 SYNE2 AKAP13 PLEC PARD3 ARHGEF6 TNS3 DCP1A	5.53e-07	1102	130	23	int:YWHAH
Interaction	YWHAZ interactions	RAF1 ARHGAP32 SHROOM3 CEP162 TBC1D5 KAT6A NCKIPSD PTPN21 INPP5F ANKRD55 SYNGAP1 MTUS1 RBM27 ARHGEF7 SSH3 PLEKHA3 SYNE2 AKAP13 PRR14L PLEC PARD3 ZNF598 TNS1 ARHGEF6 DCP1A	9.81e-07	1319	130	25	int:YWHAZ
Interaction	ZYX interactions	SECISBP2L ARHGAP32 SHROOM3 TIPARP KIDINS220 ARHGEF7 KIAA1217 AKAP13 POC5 ZNF598 ZHX1 DCP1A	1.51e-06	329	130	12	int:ZYX
Interaction	DMD interactions	REST TIPARP KCNA4 SYNE2 FOXP1 TNS1 TNS3 SOS1	3.73e-06	141	130	8	int:DMD
Interaction	ARHGAP26 interactions	MICAL1 SRPK1 C2CD2 SYNGAP1 SYNE2 AKAP13 SOS1	1.28e-05	120	130	7	int:ARHGAP26
Interaction	YWHAG interactions	RAF1 MAGI1 ARHGAP32 SHROOM3 CEP162 TBC1D5 NCKIPSD SRPK1 PTPN21 INPP5F ANKRD55 SYNGAP1 MTUS1 ARHGEF7 CEP250 PLEKHA3 SYNE2 AKAP13 PARD3 ARHGEF6 TNS3 DCP1A	1.52e-05	1248	130	22	int:YWHAG
Interaction	SYNE3 interactions	ARHGAP32 SHROOM3 PLOD3 SMPD4 ZNF318 ZCCHC14 CCDC66 KIDINS220 KIAA1217 SYNE2 PLEC ZNF598	3.11e-05	444	130	12	int:SYNE3
Interaction	ARHGAP42 interactions	SYNGAP1 SYNE2 AKAP13 PLEC SOS1	4.25e-05	60	130	5	int:ARHGAP42
Interaction	FMR1 interactions	HMBOX1 RAF1 MAGI1 KAT6A ZNFX1 SYNGAP1 TIA1 FAM120C KIAA1217 SHARPIN PARD3 ZNF598 TNS1	4.42e-05	536	130	13	int:FMR1
Interaction	PRICKLE2 interactions	SYNGAP1 ARHGEF7 SYNE2 AKAP13 SOS1	4.98e-05	62	130	5	int:PRICKLE2
Interaction	SORBS3 interactions	RAF1 MICAL1 PLOD3 NCKIPSD ARHGEF7 KIAA1217 TNS1 IQUB	5.07e-05	202	130	8	int:SORBS3
Interaction	FGD4 interactions	SYNGAP1 ARHGEF7 SYNE2 AKAP13 PLEC	5.81e-05	64	130	5	int:FGD4
Interaction	FLOT1 interactions	RAF1 MAGI1 ARHGAP32 ANK3 SRPK1 SLC39A10 TIPARP KIDINS220 ARHGEF7 KIAA1217 PLEC PARD3	5.97e-05	475	130	12	int:FLOT1
Interaction	CEP135 interactions	ARHGAP32 SHROOM3 CEP162 SMPD4 SRPK1 SFI1 CCDC66 CEP250 ULK2	6.91e-05	272	130	9	int:CEP135
Interaction	PDLIM5 interactions	RAF1 TIPARP SYNGAP1 ARHGEF7 SYNE2 AKAP13 PLEC ZNF598 SOS1	7.11e-05	273	130	9	int:PDLIM5
Interaction	PHF21A interactions	RAF1 ZDBF2 ZNF318 INPP5F TIPARP RLF PLEC PC DCP1A TANGO6	7.83e-05	343	130	10	int:PHF21A
Interaction	LPXN interactions	SFI1 SYNGAP1 ARHGEF7 SYNE2 ARHGEF6 SOS1	1.02e-04	115	130	6	int:LPXN
Interaction	KIAA1217 interactions	RAF1 ANK3 BRSK2 TIPARP KIAA1217 PARD3	1.02e-04	115	130	6	int:KIAA1217
Interaction	PCM1 interactions	RAF1 CEP162 LCA5L TTC3 TIPARP CCDC66 C6orf118 FAM120C KIAA1217 CEP250 POC5	1.19e-04	434	130	11	int:PCM1
Interaction	UPP1 interactions	RAF1 ZNFX1 MTUS1 PRR14L TANGO6	1.50e-04	78	130	5	int:UPP1
Interaction	GAB1 interactions	ARHGAP32 GTF2A1L NTRK2 PARD3 TNS1 TNS3 SOS1	1.58e-04	178	130	7	int:GAB1
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	ARHGEF7 AKAP13 ARHGEF6 SOS1	3.13e-04	66	89	4	722
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	DOCK10 ARHGEF7 PLEKHA3 AKAP13 ARHGEF6 SOS1	5.39e-04	206	89	6	682
GeneFamily	DNAJ (HSP40) heat shock proteins\|C2 tensin-type domain containing	TNS1 TNS3	6.58e-04	8	89	2	837
GeneFamily	AAA ATPases\|Peroxins	PEX12 PEX14	2.75e-03	16	89	2	957
GeneFamily	Zinc fingers\|Zinc fingers PARP-type\|Poly(ADP-ribose) polymerases	PARP14 TIPARP	3.11e-03	17	89	2	684
Coexpression	GSE10094_LCMV_VS_LISTERIA_IND_EFF_CD4_TCELL_UP	MICAL1 NRBF2 DOCK10 ZNF318 PTPN21 PARP14 RIOX2 RBM27 PNPLA7 DCP1A	8.18e-08	199	134	10	M3046
Coexpression	GSE14699_NAIVE_VS_DELETIONAL_TOLERANCE_CD8_TCELL_UP	FAM193B ZNF318 TTC3 ADCY7 EML5 CHST15 FOXP1 PNPLA7 MGRN1	9.20e-08	152	134	9	M2938
Coexpression	GSE22601_IMMATURE_CD4_SINGLE_POSITIVE_VS_DOUBLE_POSITIVE_THYMOCYTE_DN	MICAL1 DOCK10 SRPK1 INPP5F PARP14 TTC3 FOXP1 AKAP13 C1QTNF12	9.39e-07	200	134	9	M6247
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	SECISBP2L KAT6A PEX14 CHD9 INPP5F C2CD2 TIPARP RLF KIDINS220 TIA1 ARHGEF7 SYNE2 AKAP13 PARD3 FUT8 ADGRA3 SOS1	1.85e-06	856	134	17	M4500
Coexpression	BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_UP	SECISBP2L HMBOX1 NRBF2 HIC2 RSC1A1 ADCY7 TIPARP GPR107 RLF ZCCHC14 MTUS1 ARHGEF7 CSNK1G1 DCP1A PDZD2 SOS1	4.90e-06	822	134	16	M6782
Coexpression	MURARO_PANCREAS_DUCTAL_CELL	MAGI1 SHROOM3 ANK3 NTRK2 TBC1D5 REST PARP14 TIPARP SERPINA1 CHST15 SLC15A1 MTUS1 KIAA1217 SYNE2 AKAP13 TMEM123 PARD3 TNS1 ADGRA3 TNS3	7.79e-06	1276	134	20	M39173
Coexpression	GSE37416_CTRL_VS_24H_F_TULARENSIS_LVS_NEUTROPHIL_UP	FOXN2 GTF2A1L PEX12 SSH3 SYNE2 ADAMTS20 ARHGEF6 NLK	7.90e-06	196	134	8	M5337
Coexpression	GSE36392_MAC_VS_NEUTROPHIL_IL25_TREATED_LUNG_UP	FAM193B CEP162 SRPK1 INPP5F CD5 CHST15 FOXP1 MPND	9.16e-06	200	134	8	M5285
Coexpression	GSE21063_CTRL_VS_ANTI_IGM_STIM_BCELL_8H_UP	BRSK2 PTPN21 PARP14 CD5 B4GALNT3 TNS3 PDZD2	1.42e-05	153	134	7	M8249
Coexpression	LAKE_ADULT_KIDNEY_C3_PROXIMAL_TUBULE_EPITHELIAL_CELLS_S1_S2	PRUNE2 ANK3 CHD9 SYNE2 AKAP13 PARD3 TNS1 PDZD2	1.89e-05	221	134	8	M39222
Coexpression	GSE13547_CTRL_VS_ANTI_IGM_STIM_ZFX_KO_BCELL_12H_DN	TTC3 EML5 CHST15 FOXP1 PNPLA7 NLK MGRN1	2.06e-05	162	134	7	M7002
Coexpression	RODRIGUES_THYROID_CARCINOMA_ANAPLASTIC_DN	MAGI1 KIDINS220 CSRNP3 MTUS1 KIAA1217 SYNE2 FOXP1 AKAP13 TNS1 ADGRA3 NLK CDON	2.32e-05	542	134	12	M19529
Coexpression	DAZARD_RESPONSE_TO_UV_NHEK_DN	FLG KAT6A CHD9 ZNF318 ZBTB24 TIPARP ZCCHC14 MTUS1 ARHGEF7	2.50e-05	300	134	9	M8702
Coexpression	GSE3565_CTRL_VS_LPS_INJECTED_DUSP1_KO_SPLENOCYTES_DN	INPP5F TTC3 ANKRD55 CHST15 CSNK1G1 AKAP13 NLK	2.91e-05	171	134	7	M6321
Coexpression	GSE14415_FOXP3_KO_NATURAL_TREG_VS_TCONV_DN	HMBOX1 TTC3 ANKRD55 EML5 CHST15 FOXP1 MGRN1	3.14e-05	173	134	7	M2953
Coexpression	LAKE_ADULT_KIDNEY_C4_PROXIMAL_TUBULE_EPITHELIAL_CELLS_S2	PRUNE2 SHROOM3 ANK3 KIAA1217 SYNE2 AKAP13 PARD3	3.50e-05	176	134	7	M39223
Coexpression	NAKAYA_PBMC_FLUMIST_AGE_18_50YO_3DY_DN	SECISBP2L RAF1 HIC1 NRBF2 KAT6A HIC2 ZDBF2 CCDC66 RBM27 FOXP1 FUT8 ZHX1 DCP1A	4.80e-05	680	134	13	M41089
Coexpression	GSE20484_MCSG_VS_CXCL4_MONOCYTE_DERIVED_MACROPHAGE_DN	TBC1D5 ADCY7 RLF ZCCHC14 KIDINS220 FOXP1 HCFC2	6.70e-05	195	134	7	M7382
Coexpression	GSE20366_TREG_VS_NAIVE_CD4_TCELL_HOMEOSTATIC_CONVERSION_DN	FAM193B TBC1D5 CHD9 ADCY7 CHST15 SLC15A1 FAM120C	7.61e-05	199	134	7	M4331
Coexpression	GSE5503_PLN_DC_VS_SPLEEN_DC_ACTIVATED_ALLOGENIC_TCELL_DN	RAF1 NRBF2 ADCY7 GPR107 RIOX2 CSNK1G1 HCFC2	7.86e-05	200	134	7	M297
Coexpression	GSE15330_HSC_VS_PRO_BCELL_DN	MICAL1 ETFDH SRPK1 TIPARP MPND PC ADGRA3	7.86e-05	200	134	7	M7063
Coexpression	GSE22589_HIV_VS_HIV_AND_SIV_INFECTED_DC_DN	FAM193B NRBF2 CHD9 RIOX2 RLF CEP250 TANGO6	7.86e-05	200	134	7	M7801
Coexpression	GSE29164_UNTREATED_VS_CD8_TCELL_TREATED_MELANOMA_DAY3_DN	NRBF2 DOCK10 CHD9 INPP5F PARP14 CD5 AKAP13	7.86e-05	200	134	7	M8486
Coexpression	GSE19888_ADENOSINE_A3R_INH_VS_ACT_IN_MAST_CELL_UP	NRBF2 PCNX3 RBM27 FAM120C POC5 HCFC2 ZNF598	7.86e-05	200	134	7	M7340
Coexpression	BHAT_ESR1_TARGETS_NOT_VIA_AKT1_DN	SHROOM3 ANK3 PTPN21 CHST15 TNS3	9.03e-05	88	134	5	M2232
Coexpression	TIEN_INTESTINE_PROBIOTICS_2HR_DN	RAF1 HIC2 INPP5F TNS3 SOS1	9.53e-05	89	134	5	M8916
Coexpression	BENPORATH_SOX2_TARGETS	HMBOX1 PCNX3 KIF26A KAT6A REST CDC7 ZCCHC14 SERPINA1 TIA1 PLEKHA3 FOXP1 MPND TMEM123	1.04e-04	734	134	13	M3835
Coexpression	GSE15330_HSC_VS_MEGAKARYOCYTE_ERYTHROID_PROGENITOR_UP	ZNF318 TTC3 EML5 CHST15 FOXP1 MGRN1	1.90e-04	162	134	6	M7005
Coexpression	GSE13547_WT_VS_ZFX_KO_BCELL_UP	SECISBP2L TBC1D5 CHD9 INPP5F CACNA1G PNPLA7	1.96e-04	163	134	6	M2997
Coexpression	GRYDER_PAX3FOXO1_ENHANCERS_IN_TADS	SCFD2 PRUNE2 MAGI1 FOXN2 DOCK10 GPR107 CDC7 CHST15 KIAA1217 FOXP1 B4GALNT3 TMEM123 PARD3 TNS3 CDON	2.08e-04	1009	134	15	M157
Coexpression	GSE40274_CTRL_VS_FOXP3_AND_PBX1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP	FAM193B MICAL1 UNC5A KIDINS220 CHST15 HCFC2	2.10e-04	165	134	6	M9105
Coexpression	AMBROSINI_FLAVOPIRIDOL_TREATMENT_TP53	MICAL1 SERPINA1 CACNA1G PARD3 MGRN1	2.27e-04	107	134	5	M8268
Coexpression	LAKE_ADULT_KIDNEY_C11_THIN_ASCENDING_LIMB	MAGI1 TBC1D5 SERPINA1 MTUS1 FOXP1 TNS3	2.39e-04	169	134	6	M39230
ToppCell	Bronchial-NucSeq-Epithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SECISBP2L MAGI1 ARHGAP32 SHROOM3 ANK3 MTUS1 KIAA1217 PARD3 FHIP1A PDZD2	5.99e-10	199	136	10	5f7da3eab58ace6cddb3179a415cd839d5767958
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SECISBP2L MAGI1 SHROOM3 ANK3 MTUS1 KIAA1217 SYNE2 PARD3 FHIP1A	2.82e-09	170	136	9	a2c738e441ced90eeeb1fcc6ca3269b918aaa298
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	MAGI1 SHROOM3 ANK3 MTUS1 KIAA1217 PARD3 FUT8 FHIP1A ADGRA3	4.21e-09	178	136	9	f5ed4a6e3eb8056b1be1fb311021710c95bdf888
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SECISBP2L MAGI1 SHROOM3 ANK3 MTUS1 KIAA1217 PARD3 FUT8 FHIP1A	5.90e-09	185	136	9	98b8ee42b89d97e4c9db01740e0c193503c68f2c
ToppCell	COPD-Epithelial-Club\|World / Disease state, Lineage and Cell class	MAGI1 SHROOM3 ANK3 MTUS1 KIAA1217 B4GALNT3 PARD3 FHIP1A ADGRA3	6.19e-09	186	136	9	3006f4ab1eaf1eb34c10ca9f7c869603d2d25744
ToppCell	COVID-19-Epithelial_cells\|COVID-19 / group, cell type (main and fine annotations)	MAGI1 SHROOM3 ANK3 MTUS1 KIAA1217 B4GALNT3 PARD3 FHIP1A PDZD2	6.79e-09	188	136	9	c9cdee6f8d42ee69f5fb335f25084603c511bd29
ToppCell	Children_(3_yrs)-Epithelial\|Children_(3_yrs) / Lineage, Cell type, age group and donor	MAGI1 SHROOM3 ANK3 MTUS1 KIAA1217 B4GALNT3 PARD3 FHIP1A PDZD2	7.80e-09	191	136	9	e432c6e1ae82dddf84314ce73d2b7a991630d905
ToppCell	Epithelial\|World / Lineage, Cell type, age group and donor	MAGI1 SHROOM3 ANK3 MTUS1 KIAA1217 B4GALNT3 PARD3 FHIP1A PDZD2	8.16e-09	192	136	9	499e8893afea5e6d3371e0bd018f7e86a524d669
ToppCell	Control-Epithelial-Club\|Control / Disease state, Lineage and Cell class	MAGI1 SHROOM3 ANK3 MTUS1 KIAA1217 B4GALNT3 PARD3 FHIP1A ADGRA3	8.16e-09	192	136	9	d84ed1ea4a03edaa18c804f75afb03bd7b1f0e16
ToppCell	Adult-Epithelial\|Adult / Lineage, Cell type, age group and donor	MAGI1 SHROOM3 ANK3 MTUS1 KIAA1217 B4GALNT3 PARD3 FHIP1A PDZD2	8.16e-09	192	136	9	efb962a5fd3b9bdfd8cf8d13c435e29c8271713e
ToppCell	renal_cortex_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	MAGI1 SHROOM3 ANK3 TBC1D5 SYNE2 FOXP1 AKAP13 PARD3 PDZD2	8.16e-09	192	136	9	e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCell	Bronchial-NucSeq-Epithelial-Epi_airway_secretory-Secretory_Club\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SECISBP2L MAGI1 SHROOM3 ANK3 PARP14 MTUS1 KIAA1217 ASB4 FHIP1A	9.77e-09	196	136	9	ed76eeb37400ca154feae9b7ebaddb6c434f8b81
ToppCell	Parenchymal-NucSeq-Epithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MAGI1 ARHGAP32 SHROOM3 ANK3 MTUS1 KIAA1217 PARD3 FHIP1A PDZD2	1.11e-08	199	136	9	5cea0d9e261903e0eaad60c28a07dff72ce65027
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)\|Adult / Lineage, Cell type, age group and donor	SECISBP2L MAGI1 SHROOM3 ANK3 MTUS1 KIAA1217 AKAP13 FUT8	3.97e-08	163	136	8	e819a1d6d28290854aa0672b3a18fa9e293d8f23
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SECISBP2L MAGI1 SHROOM3 ANK3 MTUS1 KIAA1217 FUT8 FHIP1A	4.57e-08	166	136	8	c20479fe7a4306320d7f26e78bf956225f00f35a
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D122\|Adult / Lineage, Cell type, age group and donor	SECISBP2L SHROOM3 CSRNP3 MTUS1 KIAA1217 ASB4 FUT8 FHIP1A	7.18e-08	176	136	8	3fee8a367bb9755aca1b7fcc968b08e51b6e9436
ToppCell	Control-Epithelial_cells-Airway_club\|Control / group, cell type (main and fine annotations)	MAGI1 SHROOM3 ANK3 MTUS1 KIAA1217 PARD3 FHIP1A CDON	8.92e-08	181	136	8	c755d23dd9aabc717dc73e2b3fa99a1f751e6507
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)\|Adult / Lineage, Cell type, age group and donor	SECISBP2L MAGI1 SHROOM3 ANK3 MTUS1 KIAA1217 FUT8 FHIP1A	1.05e-07	185	136	8	673f0c688ae6984bc8027df2da335787924f4137
ToppCell	COVID-19-Epithelial_cells-Airway_club\|COVID-19 / group, cell type (main and fine annotations)	MAGI1 SHROOM3 ANK3 MTUS1 KIAA1217 B4GALNT3 PARD3 FHIP1A	1.05e-07	185	136	8	cfe6fd73d817e173fe803bc1683c291d9bcb8608
ToppCell	Control-Epithelial-Club\|World / Disease state, Lineage and Cell class	MAGI1 SHROOM3 ANK3 MTUS1 KIAA1217 PARD3 FHIP1A ADGRA3	1.10e-07	186	136	8	9798428691408e17ff2af2fe2d1b345f074d67e4
ToppCell	Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)\|World / Lineage, Cell type, age group and donor	SECISBP2L MAGI1 SHROOM3 ANK3 MTUS1 KIAA1217 FUT8 FHIP1A	1.15e-07	187	136	8	81cc8435b2704a9a8287b3f54acaae0f11dd4ac7
ToppCell	IPF-Epithelial-Club\|IPF / Disease state, Lineage and Cell class	MAGI1 SHROOM3 ANK3 MTUS1 KIAA1217 B4GALNT3 PARD3 FHIP1A	1.24e-07	189	136	8	f3fcef008ef252b29ac6d567fef27f9acf9cd70f
ToppCell	COPD-Epithelial-Club\|COPD / Disease state, Lineage and Cell class	MAGI1 SHROOM3 MTUS1 KIAA1217 B4GALNT3 PARD3 FHIP1A ADGRA3	1.35e-07	191	136	8	c909cf5fa0e6519aa93a47d2c3fcd2ae2163cd8d
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SECISBP2L MAGI1 SHROOM3 ANK3 MTUS1 PARD3 FHIP1A PDZD2	1.35e-07	191	136	8	a0332a4ef629510fb313ec119195c44a3f704a80
ToppCell	IPF-Epithelial-Club\|World / Disease state, Lineage and Cell class	MAGI1 SHROOM3 ANK3 MTUS1 KIAA1217 B4GALNT3 PARD3 FHIP1A	1.35e-07	191	136	8	3c88a6f1d74bb3b9173cd0ea3a63c6d9570e3954
ToppCell	Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)\|World / Lineage, Cell type, age group and donor	SECISBP2L MAGI1 SHROOM3 ANK3 MTUS1 KIAA1217 PARD3 FHIP1A	1.35e-07	191	136	8	d3733c8c4bda70c4390e5601fdda6188a64be944
ToppCell	Control-Multiplet-Multiplet\|World / Disease state, Lineage and Cell class	MAGI1 SHROOM3 ANK3 MTUS1 KIAA1217 SYNE2 PARD3 FHIP1A	1.40e-07	192	136	8	1bfd022d5b87cf8a5d5069f559339a553a52a0a2
ToppCell	COPD-Epithelial\|COPD / Disease state, Lineage and Cell class	MAGI1 SHROOM3 ANK3 MTUS1 KIAA1217 B4GALNT3 PARD3 FHIP1A	1.40e-07	192	136	8	0644fad5df18f0021f6f49cca996d8cf47f972ff
ToppCell	Epithelial-club_cell\|World / Lineage, Cell type, age group and donor	MAGI1 SHROOM3 ANK3 MTUS1 KIAA1217 B4GALNT3 FUT8 FHIP1A	1.46e-07	193	136	8	2bdd09004fa433550958ec42ba4b06271a4aaf7c
ToppCell	Control-Multiplet\|Control / Disease state, Lineage and Cell class	MAGI1 SHROOM3 ANK3 MTUS1 KIAA1217 SYNE2 PARD3 FHIP1A	1.58e-07	195	136	8	618900c80bea09d46dad3f741bd1bff8bf0a64ee
ToppCell	Children_(3_yrs)-Epithelial-club_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	MAGI1 SHROOM3 ANK3 KCNA4 KIAA1217 SYNE2 B4GALNT3 FHIP1A	1.58e-07	195	136	8	dccc32fcf772e2504de7f663ef0a5bd8e23e92fc
ToppCell	Control-Multiplet-Multiplet\|Control / Disease state, Lineage and Cell class	MAGI1 SHROOM3 ANK3 MTUS1 KIAA1217 SYNE2 PARD3 FHIP1A	1.58e-07	195	136	8	06ac685855e14e4dd2cbe6d0e73f894f2eeff91f
ToppCell	Control-Epithelial\|Control / Disease state, Lineage and Cell class	MAGI1 SHROOM3 ANK3 MTUS1 KIAA1217 B4GALNT3 PARD3 FHIP1A	1.58e-07	195	136	8	1798c3b89b1b5ff4f5777d2b9f52dc81cdad28fa
ToppCell	Bronchial-NucSeq\|Bronchial / Cell types per location group and 10X technology with lineage, and cell group designations	MAGI1 SHROOM3 ANK3 TBC1D5 PARD3 FHIP1A PDZD2 SOS1	1.64e-07	196	136	8	ab53c742866945545a92e2e61850d63c80d9a2a6
ToppCell	Parenchymal-NucSeq\|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations	MAGI1 ARHGAP32 SHROOM3 ANK3 TBC1D5 PARD3 FHIP1A PDZD2	1.78e-07	198	136	8	1996373bdccc55aac347d349bd22f6aad6d0c668
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D231\|Adult / Lineage, Cell type, age group and donor	SECISBP2L SHROOM3 MTUS1 KIAA1217 SYNE2 FUT8 ADGRA3	9.41e-07	170	136	7	269dee5abca9f6aa079f116f0d8f1d198604d9d4
ToppCell	Control-Epithelial_cells-ECM-high_epithelial\|Control / group, cell type (main and fine annotations)	MAGI1 SHROOM3 ANK3 PARD3 TNS1 FHIP1A PDZD2	9.41e-07	170	136	7	e2023d66e70983c87dacbd6181d3426488d1fc57
ToppCell	Fetal_29-31_weeks-Epithelial-club_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	MAGI1 ANK3 MTUS1 KIAA1217 B4GALNT3 FUT8 FHIP1A	1.19e-06	176	136	7	3bbac5c2397535631fce8fa98f6ddb4fe0260351
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)\|Children_(3_yrs) / Lineage, Cell type, age group and donor	MAGI1 SHROOM3 ANK3 MTUS1 KIAA1217 PARD3 FHIP1A	1.33e-06	179	136	7	cb38b54261a7af5ee3347e64c8aa880a77ed0763
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SECISBP2L MAGI1 SHROOM3 ANK3 MTUS1 FHIP1A ADGRA3	1.60e-06	184	136	7	102105ae1a5ef6d42a43f6d9b00f12ed0690ddb7
ToppCell	Control-Epithelial_alveolar-AT_2-Differentiating_AT2\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SECISBP2L ARHGAP32 SHROOM3 ANK3 MTUS1 FHIP1A CDON	1.66e-06	185	136	7	0d2add28ac1f4fa6de7699be009bf8391badaf4c
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	SECISBP2L MAGI1 SHROOM3 ANK3 MTUS1 KIAA1217 FHIP1A	1.72e-06	186	136	7	2ea5ff14861e5f91d0e6a5767c403a24045d715c
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 SLC22A24 SERPINA1 SLC15A1 SYNE2 PC PDZD2	1.72e-06	186	136	7	b1edc341d6684b347dc9e21b34f62f51d095d735
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	MAGI1 SHROOM3 ANK3 MTUS1 AKAP13 FHIP1A PDZD2	1.78e-06	187	136	7	5df9e1f5ca32217af255e76e6fb5afa346337811
ToppCell	Control-Epithelial_cells\|Control / group, cell type (main and fine annotations)	MAGI1 SHROOM3 ANK3 MTUS1 PARD3 FHIP1A PDZD2	1.84e-06	188	136	7	707ebf76cc6fb600b2f07793cf4ea9482c0de79d
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	MAGI1 SHROOM3 PTPN21 PARD3 TNS1 FHIP1A PDZD2	1.98e-06	190	136	7	30b50d183d7649146eb1e79b47ba897355f1998a
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	MAGI1 SHROOM3 ANK3 MTUS1 KIAA1217 FHIP1A PDZD2	2.05e-06	191	136	7	ca5669bd6f4a17471acae3eb229f845cc2e08efa
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	MAGI1 SHROOM3 ANK3 MTUS1 AKAP13 FHIP1A PDZD2	2.12e-06	192	136	7	29f49f00770c991b5f27e4cb701dd2d2d6cb7178
ToppCell	Fetal_29-31_weeks-Epithelial\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	MAGI1 SHROOM3 ANK3 MTUS1 KIAA1217 PARD3 FHIP1A	2.19e-06	193	136	7	a0ca3231992f14abcf1a6129573bace320e89d2a
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 MAGI1 SHROOM3 ANK3 SYNE2 PARD3 FHIP1A	2.27e-06	194	136	7	7002937e8903e037332a215d00fbc7c7843b33f2
ToppCell	nucseq-Epithelial-Epithelial_Alveolar\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MAGI1 SHROOM3 ANK3 MTUS1 PARD3 FHIP1A PDZD2	2.27e-06	194	136	7	53f3e49e91b1096f3226010e2de767efb490dfe4
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SECISBP2L MAGI1 SHROOM3 ANK3 MTUS1 PARD3 PDZD2	2.27e-06	194	136	7	97534c8bba895a7913665e03ae4e5c4a6ad71daf
ToppCell	nucseq-Epithelial\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MAGI1 SHROOM3 ANK3 MTUS1 PARD3 FHIP1A PDZD2	2.35e-06	195	136	7	9406866f99555198a9be311fbd65751b70f35446
ToppCell	IPF-Epithelial\|IPF / Disease state, Lineage and Cell class	MAGI1 SHROOM3 ANK3 C6orf118 KIAA1217 PARD3 FHIP1A	2.43e-06	196	136	7	87d9881cfec461a5d89b688a83749b618c519485
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 ANK3 SERPINA1 SYNE2 PARD3 FHIP1A TNS3	2.51e-06	197	136	7	7e93a97b5ac5ae2f77a4b3141082a1463fed00dd
ToppCell	(11)_FOXN4+-(2)_GFP_FOXI1\|(11)_FOXN4+ / shred by cell type by condition	SHROOM3 CEP162 REST TTC3 CHST15 SYNE2 SOS1	2.60e-06	198	136	7	76d40b8c2f8399725b3a62ee2ae0896559cf91eb
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MAGI1 SHROOM3 ANK3 MTUS1 PARD3 FHIP1A PDZD2	2.69e-06	199	136	7	8587bd98de7767a575088afbea07a1feb4516b9b
ToppCell	mild-CD4+_T_naive\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ANK3 DOCK10 TTC3 ANKRD55 SYNE2 FOXP1 TMEM123	2.69e-06	199	136	7	3e4baaf4ee23f257d821194468102c00a8ad2f21
ToppCell	Tracheal-NucSeq\|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations	MAGI1 ARHGAP32 ANK3 TBC1D5 PARD3 FUT8 SOS1	2.69e-06	199	136	7	94b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCell	facs-Liver-Non-hepatocytes-3m-Lymphocytic-NK_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MICAL1 DOCK10 F2RL2 TMEM123 ARHGEF6 PDZD2	7.94e-06	154	136	6	75eac6970259a6916fcfa6d3400509cfa2d98d9d
ToppCell	CD8+_Memory_T_cell-RSV-6\|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster	HIC1 GLS2 PCNX3 C2CD2 MTUS1 C1QTNF12	9.20e-06	158	136	6	5ae737757a49fc96bde1e57e02066f9f65654ea1
ToppCell	10x5'-blood-Lymphocytic_T_CD4-T_CD4/CD8\|blood / Manually curated celltypes from each tissue	ANK3 KAT6A DOCK10 SFI1 SYNE2 FOXP1	1.06e-05	162	136	6	b4535bcb3f469bc139e73f1122f4070013e5a1de
ToppCell	Fetal_29-31_weeks-Epithelial-club_cell-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	MAGI1 SHROOM3 ANK3 MTUS1 KIAA1217 FUT8	1.06e-05	162	136	6	5c9bc3c3857a99d8a3caf359a7eb279ce9cc1c81
ToppCell	P15-Epithelial-airway_epithelial_cell-ciliated_cell_of_airway\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	PCNX3 SFI1 MRC2 PNPLA7 IQUB CDON	1.26e-05	167	136	6	5c3d0763f73628c71c71f9883556bb4f1639f3cc
ToppCell	Control\|World / group, cell type (main and fine annotations)	MAGI1 SHROOM3 ANK3 PARD3 FHIP1A PDZD2	1.30e-05	168	136	6	a3511faf2cd2c2b9c8363c8b99da3f3609c43ed6
ToppCell	Mild/Remission-B_naive-4\|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)	SECISBP2L ARHGAP32 KAT6A ZNF318 FOXP1 PNPLA7	1.35e-05	169	136	6	c3a6179a64589a370108fea809b157839347759c
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L2-6_VIP_VIP\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CDHR1 DOCK10 F2RL2 CASP12 CHST15 PARD3	1.64e-05	175	136	6	e78bf0c33a741bb97e987e41ac33da9e623a08ec
ToppCell	B_cells-Naive_B_cells_\|B_cells / Immune cells in Kidney/Urine in Lupus Nephritis	ARHGAP32 ZNF318 PARP14 ARHGEF7 FOXP1 PNPLA7	1.81e-05	178	136	6	71ac2eca5cf13a91f86b80690748b0788392dcfc
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	SECISBP2L MAGI1 ANK3 MTUS1 KIAA1217 FHIP1A	1.87e-05	179	136	6	815b959ce8721c5ded70c0ca6e318dafc691746e
ToppCell	10x5'-Liver-Lymphocytic_T_CD4-T_CD4/CD8\|Liver / Manually curated celltypes from each tissue	ANK3 SFI1 SLC39A10 SYNE2 FOXP1 FUT8	1.99e-05	181	136	6	f2315414e714ac86211546a935660c4be6e85f1b
ToppCell	COPD-Epithelial-ATII\|World / Disease state, Lineage and Cell class	MAGI1 SHROOM3 ANK3 MTUS1 PARD3 FHIP1A	2.12e-05	183	136	6	8e9aab4eeec2e282c2cab9bfca6dbf40d660c7b9
ToppCell	LPS_only-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SHROOM3 MTUS1 KIAA1217 SYNE2 FHIP1A TNS3	2.18e-05	184	136	6	42ce855b4f8475a8298192feec785bdc69bc5bb0
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT1-AT1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MAGI1 SHROOM3 PTPN21 PARD3 TNS1 PDZD2	2.18e-05	184	136	6	57c792e6e2fedba25d3350ffe649fd74750b579d
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ANK3 ANKRD55 CCDC66 CD5 SYNE2 FOXP1	2.18e-05	184	136	6	5350b58aa9979631228835d11eb45ddf81d08bff
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MAGI1 SHROOM3 PTPN21 PARD3 TNS1 PDZD2	2.18e-05	184	136	6	d7bd0f0c607bade67c99e9fb3578a570298bf926
ToppCell	IPF-Epithelial-ATII\|World / Disease state, Lineage and Cell class	MAGI1 SHROOM3 ANK3 MTUS1 PARD3 FHIP1A	2.32e-05	186	136	6	6a4ff2da0af0f5e590d9f9daa5b5e9ac8c868947
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 SHROOM3 ANK3 SYNE2 PARD3 FUT8	2.32e-05	186	136	6	b87acc80b7baa41681e4ed11d5537b9fbf5832f5
ToppCell	Control-Epithelial-ATII\|World / Disease state, Lineage and Cell class	MAGI1 SHROOM3 ANK3 MTUS1 PARD3 FHIP1A	2.32e-05	186	136	6	f4b6e401e19a71beddc73d8a1e08359f7c4025cf
ToppCell	Control-Endothelial-Endothelial-Alv_Cap\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	HMBOX1 FOXN2 NTRK2 KAT6A KIDINS220 KIAA1217	2.39e-05	187	136	6	ea9d34bcd3bd1f36745846309ede349773de501a
ToppCell	(1)_T_CD4_naive\|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)	ANK3 ANKRD55 CCDC66 CD5 SYNE2 FOXP1	2.46e-05	188	136	6	b8f67ac2faadd5b848955e43ab5d6cf5e49b3681
ToppCell	COPD-Epithelial-ATII\|COPD / Disease state, Lineage and Cell class	MAGI1 SHROOM3 ANK3 MTUS1 PARD3 FHIP1A	2.46e-05	188	136	6	eb6d79d733b53f64ca615bb777c64ed456866549
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c06-NR4A2\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ANK3 ANKRD55 CD5 SYNE2 FOXP1 TMEM123	2.54e-05	189	136	6	8130102c41b2978a8b83f765ce383f836a464795
ToppCell	COVID-19-lung-Secretory\|lung / Disease (COVID-19 only), tissue and cell type	SHROOM3 ANK3 MTUS1 KIAA1217 B4GALNT3 FHIP1A	2.54e-05	189	136	6	84d48e3ed25bebb8bb8074b3a2c5e2e88cff7f25
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	SECISBP2L MAGI1 SHROOM3 ANK3 KIAA1217 FHIP1A	2.61e-05	190	136	6	8aea807a2bcf0b653b4de6202b6ecb0f0683cc2e
ToppCell	Control-Epithelial-ATII\|Control / Disease state, Lineage and Cell class	MAGI1 SHROOM3 ANK3 MTUS1 PARD3 FHIP1A	2.61e-05	190	136	6	d50902a3abcc18aafa36d83cc2c6e07d7f7cb197
ToppCell	IPF-Epithelial-Goblet\|IPF / Disease state, Lineage and Cell class	SHROOM3 MTUS1 KIAA1217 B4GALNT3 PARD3 FHIP1A	2.61e-05	190	136	6	e41dd5a997ad9952810ffecb57737c03ea1d88b3
ToppCell	(1)_T_CD4_fh\|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)	ANK3 ANKRD55 CD5 MTUS1 SYNE2 AKAP13	2.69e-05	191	136	6	66ddff9a99092cb384b9fb2a3ba95ddbebed67cc
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ANK3 SFI1 CCDC66 CD5 SYNE2 FOXP1	2.69e-05	191	136	6	d9a6f61fcda4f5352488f7f55cb9b57aeacc717f
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	SFI1 TTC3 CCDC66 CD5 MRC2 SYNE2	2.69e-05	191	136	6	696921a4f160b6b55698652488ed781e855e5e51
ToppCell	P07-Mesenchymal-developing_mesenchymal_cell-mesenchymal_myogenic_precursor_(Axin2+)\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	SHROOM3 DOCK10 TIPARP PDE8B ARHGEF6 PDZD2	2.69e-05	191	136	6	2ad717b59215ad8d933e9637d363b65d7298e5d4
ToppCell	COVID_non-vent-Lymphocytic-T_cell-CD4+_T_cell_(ISG_high)\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	ANK3 TTC3 ANKRD55 CD5 FOXP1 TMEM123	2.77e-05	192	136	6	35557254738844c27ffcd00f3287fbcc0a4d0f3b
ToppCell	Epithelial-alveolar_epithelial_cell_type_2\|World / Lineage, Cell type, age group and donor	MAGI1 SHROOM3 ANK3 MTUS1 FHIP1A PDZD2	2.77e-05	192	136	6	58c3737be7acce39fd2b91d70d6d7b2bbaa4f710
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	MAGI1 ANK3 MTUS1 KIAA1217 FHIP1A PDZD2	2.77e-05	192	136	6	fb2f0e897228f808d9ff734ad05e9b49dc38fa50
ToppCell	COVID-19_Moderate-CD4+_T_activated\|World / disease group, cell group and cell class	ANK3 CCDC66 CD5 SYNE2 FOXP1 TMEM123	2.85e-05	193	136	6	c2a2a2c14a7085690262db5c2a70e38db67dee18
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	SECISBP2L TBC1D5 CHD9 ZDBF2 PARP14 MFSD4B	2.85e-05	193	136	6	08696a99309f5b088692ddac8cca35413b5e810d
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT2-AT2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	SECISBP2L SHROOM3 ANK3 MTUS1 PARD3 FHIP1A	2.85e-05	193	136	6	fd4d3c0d7caf8a2fff5b3d901fc28d19a8163cdf
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 MAGI1 SHROOM3 ANK3 PARD3 FHIP1A	2.85e-05	193	136	6	3866667dd221612589ae50f5c52f73a183a49ce6
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	SECISBP2L SHROOM3 ANK3 MTUS1 PARD3 FHIP1A	2.85e-05	193	136	6	f3cc7cfdbc164a4ed42f87647111522b7d393bcb
ToppCell	severe-CD4+_Tcm\|severe / disease stage, cell group and cell class	ANK3 ANKRD55 CCDC66 CD5 FOXP1 TMEM123	2.94e-05	194	136	6	380fbd19b72af6767f98bbf50329686b76d59c54
ToppCell	RA-03._Atrial_Cardiomyocyte\|World / Chamber and Cluster_Paper	PRUNE2 MAGI1 ANK3 NTRK2 NMRK2 PDE8B	2.94e-05	194	136	6	89812fb164065041357bb37a3c2d87028ec3de4e
Drug	Oxantel pamoate [68813-55-8]; Up 200; 6.6uM; MCF7; HT_HG-U133A	MICAL1 PTPN21 C2CD2 GPR107 SERPINA1 FAM120C PDE8B PLEC PARD3 TNS3	2.57e-07	196	134	10	5338_UP
Drug	Digitoxigenin [143-62-4]; Down 200; 10.6uM; PC3; HT_HG-U133A	ANK3 TBC1D5 SMARCAL1 ZNF318 ZBTB24 CDC7 MTUS1 CEP250 TNS1	2.02e-06	191	134	9	4217_DN
Drug	Oxymetazoline hydrochloride [2315-02-8]; Down 200; 13.4uM; PC3; HT_HG-U133A	ARHGAP32 ZNF318 GPR107 KIDINS220 CSRNP3 CSNK1G1 HCFC2 PARD3 ULK2	2.83e-06	199	134	9	6350_DN
Drug	irinotecan HCl; Down 200; 100uM; MCF7; HT_HG-U133A	HMBOX1 CHD9 ARHGEF7 AKAP13 PARD3 FUT8 NLK TNS3	9.11e-06	174	134	8	7530_DN
Drug	Clenbuterol hydrochloride [21898-19-1]; Down 200; 12.8uM; PC3; HT_HG-U133A	GLS2 ANK3 NCKIPSD HIC2 PTPN21 FAM120C TNS1 NLK	1.93e-05	193	134	8	4671_DN
Drug	Etofylline [519-37-9]; Up 200; 17.8uM; HL60; HG-U133A	CEP162 HIC2 SSH3 SHARPIN AKAP13 PLEC PARD3 TNS3	2.08e-05	195	134	8	1409_UP
Drug	2-propylpentanoic acid; Down 200; 1000uM; MCF7; HT_HG-U133A	MICAL1 GLS2 NCKIPSD PTPN21 STARD5 ZCCHC14 SERPINA1 SSH3	2.16e-05	196	134	8	5569_DN
Drug	Cefmetazole sodium salt [56796-39-5]; Down 200; 8.2uM; MCF7; HT_HG-U133A	GLS2 CEP162 HIC2 GPR107 STARD5 KIDINS220 SSH3 ARHGEF6	2.16e-05	196	134	8	7222_DN
Drug	fluphenazine dihydrochloride; Down 200; 10uM; HL60; HT_HG-U133A	ARHGAP32 ANK3 TBC1D5 REST ANKRD55 GPR107 CACNA1G TNS1	2.16e-05	196	134	8	2697_DN
Drug	Aztreonam [78110-38-0]; Down 200; 9.2uM; MCF7; HT_HG-U133A	FOXN2 GLS2 CEP162 ZNF318 CEP250 HCFC2 PARD3 ULK2	2.24e-05	197	134	8	2282_DN
Drug	Ticarcillin sodium [4697-14-7]; Down 200; 9.4uM; MCF7; HT_HG-U133A	SECISBP2L PEX14 SFI1 PTPN21 AKAP13 PARD3 PC ULK2	2.24e-05	197	134	8	7185_DN
Drug	Reserpinic acid hydrochloride; Down 200; 9.2uM; PC3; HT_HG-U133A	GLS2 STARD5 SERPINA1 AKAP13 PLEC PARD3 PC CDON	2.32e-05	198	134	8	6603_DN
Drug	PHA-00851261E [724719-49-7]; Up 200; 1uM; PC3; HT_HG-U133A	FOXN2 NTRK2 SOX30 KAT6A DOCK10 REST SLC15A1 PRR14L	2.32e-05	198	134	8	4333_UP
Drug	Xylazine [7361-61-7]; Down 200; 18.2uM; HL60; HT_HG-U133A	ARHGAP32 KAT6A REST SSH3 SHARPIN AKAP13 PARD3 TNS1	2.41e-05	199	134	8	2132_DN
Drug	Piroxicam [36322-90-4]; Up 200; 12uM; MCF7; HT_HG-U133A	MAGI1 CEP162 KAT6A HIC2 SFI1 PTPN21 CEP250 TNS1	2.41e-05	199	134	8	7445_UP
Drug	Proxyphylline [603-00-9]; Up 200; 16.8uM; PC3; HT_HG-U133A	MICAL1 SFI1 REST GPR107 MTUS1 MRC2 AKAP13 TNS1	2.41e-05	199	134	8	7290_UP
Drug	irinotecan HCl; Down 200; 100uM; PC3; HT_HG-U133A	PEX14 CHD9 CHST15 ARHGEF7 AKAP13 PARD3 TNS3	7.03e-05	171	134	7	7535_DN
Drug	Lycorine hydrochloride [2188-68-3]; Down 200; 12.4uM; PC3; HT_HG-U133A	ARHGAP32 TBC1D5 DOCK10 ZNF318 CDC7 FUT8 PDZD2	1.04e-04	182	134	7	3808_DN
Drug	0173570-0000 [211245-44-2]; Down 200; 10uM; PC3; HT_HG-U133A	GLS2 HIC2 PTPN21 TIPARP GPR107 MTUS1 PLEC	1.31e-04	189	134	7	3690_DN
Drug	Fenbufen [36330-85-5]; Down 200; 15.8uM; PC3; HT_HG-U133A	SECISBP2L FOXN2 GLS2 NTRK2 KAT6A REST AKAP13	1.40e-04	191	134	7	4279_DN
Drug	felodipine; Down 200; 10uM; MCF7; HT_HG-U133A_EA	ARHGAP32 TBC1D5 PEX14 REST PLEC PARD3 ARHGEF6	1.49e-04	193	134	7	965_DN
Drug	Rapamycin; Down 200; 0.1uM; MCF7; HT_HG-U133A	HIC2 ZCCHC14 FAM120C PDE8B SSH3 CACNA1G TNS1	1.49e-04	193	134	7	5602_DN
Drug	Cyanocobalamin [68-19-9]; Down 200; 3uM; PC3; HT_HG-U133A	TBC1D5 PTPN21 MTUS1 CEP250 HCFC2 PDZD2 SOS1	1.54e-04	194	134	7	4572_DN
Drug	radicicol; Down 200; 0.1uM; PC3; HT_HG-U133A	FOXN2 TBC1D5 SFI1 STARD5 KIDINS220 CEP250 TNS1	1.54e-04	194	134	7	5952_DN
Drug	radicicol; Up 200; 0.1uM; PC3; HG-U133A	ARHGAP32 DOCK10 ADCY7 CD5 MTUS1 DCP1A PDZD2	1.59e-04	195	134	7	449_UP
Drug	Risperidone [106266-06-2]; Down 200; 9.8uM; MCF7; HT_HG-U133A	GLS2 REST ZCCHC14 PDE8B SSH3 AKAP13 PRR14L	1.59e-04	195	134	7	3508_DN
Drug	Tetrahydroalstonine [6474-90-4]; Down 200; 11.4uM; MCF7; HT_HG-U133A	MAGI1 GLS2 PTPN21 GPR107 SERPINA1 SSH3 AKAP13	1.59e-04	195	134	7	2748_DN
Drug	Propofol [2078-54-8]; Down 200; 22.4uM; PC3; HT_HG-U133A	PEX14 REST PTPN21 SERPINA1 ARHGEF7 PDE8B SSH3	1.59e-04	195	134	7	6707_DN
Drug	Phensuximide [86-34-0]; Up 200; 21.2uM; PC3; HT_HG-U133A	FOXN2 GLS2 SFI1 STARD5 FAM120C MRC2 TNS1	1.64e-04	196	134	7	5097_UP
Drug	Hexamethonium dibromide dihydrate [55-97-0]; Up 200; 10uM; MCF7; HT_HG-U133A	DOCK10 SFI1 GPR107 FAM120C CEP250 CACNA1G PARD3	1.64e-04	196	134	7	4965_UP
Drug	Epivincamine [6835-99-0]; Down 200; 11.2uM; MCF7; HT_HG-U133A	FOXN2 REST STARD5 SERPINA1 SSH3 AKAP13 PARD3	1.64e-04	196	134	7	2775_DN
Drug	Gabazine [105538-73-6]; Up 200; 10.8uM; MCF7; HT_HG-U133A	NTRK2 KAT6A SLC30A3 SLC15A1 MRC2 SSH3 ULK2	1.64e-04	196	134	7	3253_UP
Drug	Mefenamic acid [61-68-7]; Up 200; 16.6uM; PC3; HT_HG-U133A	PEX14 SERPINA1 KIDINS220 MTUS1 SYNE2 AKAP13 ULK2	1.64e-04	196	134	7	1821_UP
Drug	Zardaverine [101975-10-4]; Down 200; 15uM; MCF7; HT_HG-U133A	MICAL1 GLS2 PTPN21 ADCY7 SSH3 AKAP13 PLEC	1.64e-04	196	134	7	4793_DN
Drug	Tocainide hydrochloride; Up 200; 17.4uM; MCF7; HT_HG-U133A	MICAL1 REST PTPN21 ZCCHC14 KIDINS220 PDE8B ARHGEF6	1.70e-04	197	134	7	7351_UP
Drug	Ethamsylate [2624-44-4]; Down 200; 15.2uM; MCF7; HT_HG-U133A	SECISBP2L NCKIPSD ADCY7 AKAP13 PLEC PARD3 DCP1A	1.70e-04	197	134	7	7335_DN
Drug	Meprylcaine hydrochloride [956-03-6]; Up 200; 14.8uM; MCF7; HT_HG-U133A	SECISBP2L MICAL1 CEP162 PEX14 ZNF318 SFI1 PTPN21	1.70e-04	197	134	7	6204_UP
Drug	Dicloxacillin sodium salt [13412-64-1]; Up 200; 8.2uM; HL60; HT_HG-U133A	FOXN2 GLS2 ANK3 GPR107 CD5 MTUS1 CDON	1.70e-04	197	134	7	2445_UP
Drug	Mycophenolic acid [24280-93-1]; Down 200; 12.4uM; MCF7; HT_HG-U133A	TBC1D5 PEX12 PTPN21 C2CD2 PDE8B PARD3 TNS3	1.70e-04	197	134	7	4137_DN
Drug	Ethamivan [304-84-7]; Up 200; 18uM; MCF7; HT_HG-U133A	SFI1 SLC15A1 SSH3 CEP250 PARD3 TNS1 CDON	1.70e-04	197	134	7	2879_UP
Drug	Ivermectin [70288-86-7]; Up 200; 4.6uM; PC3; HT_HG-U133A	ANK3 SOX30 GPR107 STARD5 MTUS1 AKAP13 PC	1.70e-04	197	134	7	2051_UP
Drug	PNU-0230031 [267429-39-0]; Down 200; 10uM; MCF7; HT_HG-U133A	MICAL1 CEP162 TBC1D5 SERPINA1 MTUS1 FAM120C CSNK1G1	1.70e-04	197	134	7	4754_DN
Drug	Folic acid [59-30-3]; Down 200; 9uM; MCF7; HT_HG-U133A	ANK3 PEX14 PTPN21 GPR107 PRR14L PLEC HCFC2	1.70e-04	197	134	7	7201_DN
Drug	rotenone; Down 200; 1uM; PC3; HT_HG-U133A	FOXN2 CEP162 STARD5 KIDINS220 SSH3 PC TNS1	1.70e-04	197	134	7	5948_DN
Drug	Mephenesin [59-47-2]; Down 200; 22uM; PC3; HT_HG-U133A	NCKIPSD ETFDH PTPN21 AKAP13 PARD3 ARHGEF6 SOS1	1.70e-04	197	134	7	7374_DN
Drug	Talampicillin hydrochloride [39878-70-1]; Down 200; 7.8uM; MCF7; HT_HG-U133A	FOXN2 PEX14 KIDINS220 SSH3 CSNK1G1 PARD3 ULK2	1.70e-04	197	134	7	3515_DN
Drug	(-)-Adenosine 3',5'-cyclic monophosphate [60-92-4]; Down 200; 12.2uM; PC3; HT_HG-U133A	REST PTPN21 GPR107 CSRNP3 AKAP13 TNS1 CDON	1.70e-04	197	134	7	5108_DN
Drug	nordihydroguaiaretic acid; Down 200; 1uM; MCF7; HT_HG-U133A	MAGI1 GLS2 KAT6A HIC2 GPR107 STARD5 NLK	1.75e-04	198	134	7	5220_DN
Drug	Isradipine [75695-93-1]; Down 200; 10.8uM; MCF7; HT_HG-U133A	MAGI1 GLS2 RLF MTUS1 PDE8B PLEC SOS1	1.75e-04	198	134	7	6508_DN
Drug	Dextromethorphan hydrobromide monohydrate [6700-34-1]; Up 200; 10.8uM; PC3; HT_HG-U133A	PRUNE2 GLS2 DOCK10 PTPN21 CD5 TNS1 SOS1	1.75e-04	198	134	7	6300_UP
Drug	Loperamide hydrochloride [34552-83-5]; Down 200; 7.8uM; MCF7; HT_HG-U133A	CEP162 ETFDH GPR107 STARD5 SERPINA1 SSH3 PLEC	1.75e-04	198	134	7	1533_DN
Drug	(R)-(+)-Atenolol [56715-13-0]; Down 200; 15uM; PC3; HT_HG-U133A	TBC1D5 HIC2 SERPINA1 CSRNP3 MTUS1 ARHGEF7 CSNK1G1	1.75e-04	198	134	7	4259_DN
Drug	PHA-00767505E [723337-45-9]; Up 200; 10uM; MCF7; HT_HG-U133A	CEP162 KAT6A DOCK10 ZNF318 SFI1 SERPINA1 FAM120C	1.75e-04	198	134	7	6550_UP
Drug	haloperidol; Down 200; 10uM; MCF7; HT_HG-U133A	CEP162 HIC2 ZNF318 GPR107 STARD5 SHARPIN HCFC2	1.75e-04	198	134	7	7003_DN
Drug	N-Acetyl-L-leucine [1188-21-2]; Down 200; 23uM; MCF7; HT_HG-U133A	GLS2 CEP162 ETFDH ZNF318 PTPN21 SHARPIN PARD3	1.75e-04	198	134	7	5683_DN
Drug	Dipyrone [5907-38-0]; Up 200; 12uM; MCF7; HT_HG-U133A	MICAL1 NTRK2 SFI1 SLC30A3 F2RL2 ADAMTS20 PDZD2	1.75e-04	198	134	7	3929_UP
Drug	Hexylcaine hydrochloride [532-76-3]; Down 200; 13.4uM; PC3; HT_HG-U133A	GLS2 SMARCAL1 ZNF318 REST PDE8B PRR14L TNS1	1.75e-04	198	134	7	5768_DN
Drug	Lactobionic acid [96-82-2]; Down 200; 11.2uM; HL60; HT_HG-U133A	ARHGAP32 CEP162 TBC1D5 DOCK10 REST TIA1 SSH3	1.75e-04	198	134	7	1309_DN
Drug	Flunixin meglumine [42461-84-7]; Down 200; 8.2uM; MCF7; HT_HG-U133A	MICAL1 FOXN2 NCKIPSD REST CEP250 AKAP13 TNS1	1.75e-04	198	134	7	4735_DN
Drug	GBR 12909 dihydrochloride [67469-78-7]; Down 200; 7.6uM; HL60; HG-U133A	SECISBP2L DOCK10 ZNF318 CDC7 TIA1 ARHGEF7 AKAP13	1.75e-04	198	134	7	1625_DN
Drug	Nifedipine [21829-25-4]; Down 200; 11.6uM; PC3; HT_HG-U133A	MICAL1 ARHGAP32 MTUS1 CEP250 TNS1 CDON PDZD2	1.75e-04	198	134	7	7303_DN
Drug	Phenelzine sulfate [156-51-4]; Down 200; 17uM; MCF7; HT_HG-U133A	MICAL1 GLS2 KAT6A PTPN21 GPR107 SSH3 AKAP13	1.81e-04	199	134	7	2319_DN
Drug	rotenone; Up 200; 1uM; PC3; HT_HG-U133A	MAGI1 NTRK2 HIC2 MTUS1 MRC2 SSH3 ULK2	1.81e-04	199	134	7	5920_UP
Drug	Etidronic acid, disodium salt [7414-83-7]; Down 200; 16uM; PC3; HT_HG-U133A	ARHGAP32 SRPK1 PTPN21 GPR107 SSH3 CSNK1G1 AKAP13	1.81e-04	199	134	7	4564_DN
Drug	Diazoxide [364-98-7]; Down 200; 17.4uM; MCF7; HT_HG-U133A	CEP162 KAT6A SFI1 KIDINS220 SSH3 CEP250 CDON	1.81e-04	199	134	7	2214_DN
Drug	Oxalamine citrate salt [1949-20-8]; Down 200; 9.2uM; PC3; HT_HG-U133A	GLS2 CEP162 FAM120C MRC2 ULK2 CDON PDZD2	1.81e-04	199	134	7	6624_DN
Drug	Scopolamine hydrochloride [55-16-3]; Down 200; 11.8uM; MCF7; HT_HG-U133A	GLS2 KAT6A REST GPR107 STARD5 SSH3 PLEC	1.81e-04	199	134	7	4803_DN
Drug	Norcyclobenzaprine [303-50-4]; Down 200; 15.4uM; MCF7; HT_HG-U133A	GLS2 TBC1D5 NCKIPSD SFI1 SSH3 AKAP13 PLEC	1.81e-04	199	134	7	2830_DN
Drug	Guanadrel sulfate [22195-34-2]; Down 200; 7.6uM; MCF7; HT_HG-U133A	FAM193B NCKIPSD PEX14 REST SSH3 PRR14L PARD3	1.86e-04	200	134	7	3438_DN
Drug	2-propylpentanoic acid; Down 200; 1000uM; HL60; HG-U133A	ARHGAP32 NTRK2 GPR107 CD5 ASB4 HTR3B TNS1	1.86e-04	200	134	7	409_DN
Drug	Imipenem [74431-23-5]; Up 200; 13.4uM; HL60; HG-U133A	CEP162 PEX12 SFI1 GPR107 MRC2 HCFC2 PARD3	1.86e-04	200	134	7	1724_UP
Drug	(-)-MK 801 hydrogen maleate [77086-19-2]; Up 200; 11.8uM; HL60; HT_HG-U133A	PRUNE2 HIC1 ANK3 HIC2 FAM120C MRC2 TNS1	1.86e-04	200	134	7	3081_UP
Drug	Ketotifen fumarate [34580-14-8]; Down 200; 9.4uM; PC3; HT_HG-U133A	MICAL1 ZNF318 GPR107 SERPINA1 SSH3 AKAP13 PRR14L	1.86e-04	200	134	7	5842_DN
Drug	(R)-(+)-Atenolol [56715-13-0]; Down 200; 15uM; MCF7; HT_HG-U133A	KAT6A ZNF318 MRC2 SSH3 PLEC NLK SOS1	1.86e-04	200	134	7	4841_DN
Disease	cortical surface area measurement	SCFD2 MAGI1 SHROOM3 GLS2 ANK3 PCNX3 CEP162 TBC1D5 BRSK2 DOCK10 REST SERPINA1 ADAMTS20 FOXP1 PARD3 PC TNS1 TANGO6 PDZD2 SOS1	2.95e-06	1345	134	20	EFO_0010736
Disease	testosterone measurement	SCFD2 RAF1 MAGI1 SHROOM3 GTF2A1L NRBF2 ANK3 ZNF318 PTPN21 SLC22A24 C2CD2 SERPINA1 PDE8B SYNE2 FOXP1 ARHGEF6 TNS3 SOS1 MGRN1	5.20e-06	1275	134	19	EFO_0004908
Disease	neuroimaging measurement	SECISBP2L SCFD2 MAGI1 SHROOM3 ANK3 TBC1D5 BRSK2 PTPN21 MFSD4B SERPINA1 ADAMTS20 FOXP1 PLEC TMEM123 PARD3 PC TNS1	7.38e-06	1069	134	17	EFO_0004346
Disease	Gingival overgrowth	REST SOS1	2.05e-05	2	134	2	cv:C0376480
Disease	Hereditary gingival fibromatosis	REST SOS1	2.05e-05	2	134	2	cv:C0399440
Disease	hair colour measurement	RAF1 SHROOM3 NRBF2 DOCK10 PEX14 MFSD4B RBM27 SYNE2 AKAP13 PARD3 C1QTNF12 PC	2.53e-05	615	134	12	EFO_0007822
Disease	platelet crit	SCFD2 HIC1 KIF26A TBC1D5 DOCK10 ZNF318 REST C2CD2 CDC7 SERPINA1 C6orf118 KCNA4 RBM27 PLEC FHIP1A	2.94e-05	952	134	15	EFO_0007985
Disease	brain measurement, neuroimaging measurement	MAGI1 ANK3 TBC1D5 BRSK2 SERPINA1 ADAMTS20 FOXP1 PLEC PARD3 TNS1 TANGO6	4.46e-05	550	134	11	EFO_0004346, EFO_0004464
Disease	alcohol consumption measurement	SECISBP2L MAGI1 FOXN2 KIF26A NTRK2 REST SLC30A3 C2CD2 SERPINA1 C6orf118 RBM27 FOXP1 KLF18 HTR3B PARD3 FUT8 TANGO6	4.96e-05	1242	134	17	EFO_0007878
Disease	Hereditary gingival fibromatosis	REST SOS1	6.12e-05	3	134	2	C0399440
Disease	PR interval	MAGI1 PCNX3 CDC7 C6orf118 MTUS1 SYNE2 FOXP1 CACNA1G PLEC HCFC2	9.20e-05	495	134	10	EFO_0004462
Disease	cortical thickness	MAGI1 SHROOM3 GLS2 TBC1D5 SMARCAL1 ZNF318 SERPINA1 SHARPIN ADAMTS20 FOXP1 PLEC PARD3 TNS1 ULK2 PDZD2	1.68e-04	1113	134	15	EFO_0004840
Disease	chronotype measurement	GLS2 ANK3 TBC1D5 ETFDH BRSK2 ZNF318 SYNGAP1 C6orf118 PDE8B FOXP1 TMEM123 PC ADGRA3	1.98e-04	882	134	13	EFO_0008328
Disease	Lung Neoplasms	SECISBP2L RAF1 ANK3 SOX30 RIOX2 SERPINA1 CHST15	2.17e-04	265	134	7	C0024121
Disease	Malignant neoplasm of lung	SECISBP2L RAF1 ANK3 SOX30 RIOX2 SERPINA1 CHST15	2.22e-04	266	134	7	C0242379
Disease	retinitis pigmentosa (implicated_via_orthology)	CCDC66 CEP250 POC5	2.47e-04	27	134	3	DOID:10584 (implicated_via_orthology)
Disease	Alcohol Related Birth Defect	ANK3 NTRK2	3.03e-04	6	134	2	C3146244
Disease	Manic Disorder	ANK3 NTRK2 SERPINA1 PC	3.12e-04	71	134	4	C0024713
Disease	reticulocyte measurement	FOXN2 GLS2 NRBF2 PEX12 REST ANKRD55 SERPINA1 KCNA4 SYNE2 FOXP1 AKAP13 TNS1 TNS3 PDZD2	3.20e-04	1053	134	14	EFO_0010700
Disease	Pilomyxoid astrocytoma	RAF1 NTRK2	4.24e-04	7	134	2	C1519086
Disease	Manic	ANK3 NTRK2 SERPINA1 PC	4.47e-04	78	134	4	C0338831
Disease	Depression, Bipolar	ANK3 NTRK2 SERPINA1 PC	4.69e-04	79	134	4	C0005587
Disease	brain connectivity measurement	MAGI1 TBC1D5 BRSK2 ADAMTS20 FOXP1 PLEC TANGO6 SOS1	5.02e-04	400	134	8	EFO_0005210
Disease	vital capacity	MICAL1 FOXN2 HIC1 SHROOM3 NRBF2 CEP162 ZBTB24 SERPINA1 MRC2 FOXP1 PARD3 PC TNS1 ARHGEF6 PDZD2	5.09e-04	1236	134	15	EFO_0004312
Disease	Noonan syndrome (is_implicated_in)	RAF1 SOS1	5.63e-04	8	134	2	DOID:3490 (is_implicated_in)
Disease	Schizophrenia	MAGI1 ARHGAP32 ANK3 NTRK2 REST PTPN21 SLC30A3 ADCY7 SYNGAP1 EML5 HTR3B FUT8	7.17e-04	883	134	12	C0036341
Disease	Noonan syndrome	RAF1 SOS1	7.22e-04	9	134	2	cv:C0028326
Disease	post-traumatic stress disorder (biomarker_via_orthology)	NTRK2 CASP12	7.22e-04	9	134	2	DOID:2055 (biomarker_via_orthology)
Disease	unipolar depression, bipolar disorder	MYO1G ANK3 NTRK2 C6orf118 SYNE2	7.48e-04	156	134	5	EFO_0003761, MONDO_0004985
Disease	mean fractional anisotropy measurement	SCFD2 SMARCAL1 FOXP1 PLEC	9.40e-04	95	134	4	EFO_0008399
Disease	reticulocyte count	MYO1G FOXN2 GLS2 NRBF2 PEX12 REST ANKRD55 SERPINA1 KCNA4 SYNE2 TNS1 TNS3 PDZD2	9.72e-04	1045	134	13	EFO_0007986
Disease	liver fat measurement	HSP90B2P RIOX2 PLEC	9.90e-04	43	134	3	EFO_0010821
Disease	Abnormality of refraction	ARHGAP32 ANK3 PKD1L1 PEX14 CCDC66 KCNA4 ADAMTS20 FOXP1 AKAP13 PARD3	1.03e-03	673	134	10	HP_0000539
Disease	Noonan Syndrome 1	RAF1 SOS1	1.10e-03	11	134	2	C4551602
Disease	PEROXISOME BIOGENESIS DISORDER 1A (ZELLWEGER)	PEX12 PEX14	1.10e-03	11	134	2	C4721541
Disease	Turner Syndrome, Male	RAF1 SOS1	1.10e-03	11	134	2	C0041409
Disease	Female Pseudo-Turner Syndrome	RAF1 SOS1	1.10e-03	11	134	2	C1527404
Disease	myocardial infarction	SHROOM3 NCKIPSD REST SERPINA1 SLC15A1 TNS1 PDZD2	1.13e-03	350	134	7	EFO_0000612
Disease	corpus callosum volume measurement	BRSK2 FOXP1 PLEC SOS1	1.14e-03	100	134	4	EFO_0010299
Disease	Zellweger Spectrum	PEX12 PEX14	1.55e-03	13	134	2	C3658299
Disease	Zellweger-Like Syndrome	PEX12 PEX14	1.55e-03	13	134	2	C0751594
Disease	advanced glycosylation end product-specific receptor, soluble measurement	B4GALNT3 FUT8	1.55e-03	13	134	2	EFO_0020131
Disease	Infantile Refsum Disease (disorder)	PEX12 PEX14	1.55e-03	13	134	2	C0282527
Disease	Situs ambiguus	SHROOM3 PKD1L1	2.07e-03	15	134	2	C0266642
Disease	RASopathy	RAF1 SOS1	2.07e-03	15	134	2	cv:C5555857
Disease	Peroxisome biogenesis disorders	PEX12 PEX14	2.07e-03	15	134	2	C1832200
Disease	Adrenoleukodystrophy, Neonatal	PEX12 PEX14	2.07e-03	15	134	2	C0282525
Disease	immature platelet measurement	MYO1G TBC1D5 DOCK10 PLEC	2.16e-03	119	134	4	EFO_0803541
Disease	teratocarcinoma-derived growth factor 1 measurement	NTRK2 TNS1	2.36e-03	16	134	2	EFO_0008297
Disease	Zellweger Syndrome	PEX12 PEX14	2.36e-03	16	134	2	C0043459
Disease	Intrahepatic cholestasis of pregnancy	SHROOM3 SERPINA1	2.36e-03	16	134	2	EFO_0009048
Disease	Dermatitis	FLG SHARPIN	2.36e-03	16	134	2	C0011603
Disease	hippocampal volume	ETFDH BRSK2 KIAA1217 SHARPIN AKAP13 PLEC	2.42e-03	297	134	6	EFO_0005035
Disease	risk-taking behaviour	GTF2A1L KIF26A NTRK2 TBC1D5 REST MFSD4B CASP12 FOXP1 CACNA1G PC	2.62e-03	764	134	10	EFO_0008579
Disease	age at menopause	GTF2A1L DOCK10 SRPK1 NMRK2 MFSD4B TIPARP	2.63e-03	302	134	6	EFO_0004704
Disease	Fetal Alcohol Syndrome	ANK3 REST	2.66e-03	17	134	2	C0015923
Disease	aspartate aminotransferase measurement	MAGI1 SHROOM3 NTRK2 TBC1D5 ETFDH INPP5F SERPINA1 RBM27 PLEKHA3 AKAP13 SOS1	2.83e-03	904	134	11	EFO_0004736
Disease	platelet measurement	HIC1 DOCK10 CHD9 REST C6orf118 PLEC	3.24e-03	315	134	6	EFO_0005036
Disease	forced expiratory volume	MICAL1 NRBF2 REST ZBTB24 SERPINA1 PDE8B FOXP1 PC TNS1 CDON	3.29e-03	789	134	10	EFO_0004314
Disease	Noonan-Like Syndrome With Loose Anagen Hair	RAF1 SOS1	3.33e-03	19	134	2	C3501846
Disease	Noonan syndrome-like disorder with loose anagen hair	RAF1 SOS1	3.33e-03	19	134	2	C1843181
Disease	Cardio-facio-cutaneous syndrome	RAF1 SOS1	3.33e-03	19	134	2	C1275081
Disease	Costello syndrome (disorder)	RAF1 SOS1	3.33e-03	19	134	2	C0587248
Disease	apolipoprotein B measurement	HMBOX1 RAF1 SERPINA1 KCNA4 CSNK1G1 SYNE2 POC5 B4GALNT3 PLEC	3.36e-03	663	134	9	EFO_0004615
Disease	sclerosing cholangitis	HSP90B2P FOXP1 TANGO6	3.40e-03	66	134	3	EFO_0004268
Disease	taurocholate measurement	FOXP1 ADGRA3	3.69e-03	20	134	2	EFO_0010538
Disease	serum homoarginine measurement	SLC15A1 TNS1	3.69e-03	20	134	2	EFO_0005421
Disease	breast size	PEX14 SERPINA1 CDON	3.86e-03	69	134	3	EFO_0004884
Disease	FEV/FEC ratio	SCFD2 NRBF2 SOX30 REST SERPINA1 MTUS1 MRC2 SYNE2 FOXP1 ZNF319 PARD3 TNS1 CDON	3.97e-03	1228	134	13	EFO_0004713
Disease	bipolar I disorder	MYO1G ANK3 PLEC PC	3.97e-03	141	134	4	EFO_0009963
Disease	severe acute respiratory syndrome, COVID-19	MAGI1 NTRK2 SLC15A1 ARHGEF7 KIAA1217 PARD3 PDZD2	4.42e-03	447	134	7	EFO_0000694, MONDO_0100096
Disease	LEOPARD Syndrome	RAF1 SOS1	4.46e-03	22	134	2	C0175704
Disease	hemoglobin change measurement	MAGI1 C6orf118	4.46e-03	22	134	2	EFO_0600027

Protein segments in the cluster

Peptide	Gene	Start	Entry
ITHAEPANVFDINSH	CDHR1	611	Q96JP9
ANHPSAVNVLTQHSD	ARHGEF6	336	Q15052
HIPQTAASHVDSSNA	B4GALNT3	296	Q6L9W6
NNQDEETPLHTAAHF	ASB4	171	Q9Y574
AAQKTDTSHHDQDHP	SERPINA1	31	P01009
AAGILATDTHHPQDS	HTR3B	16	O95264
ISTSALENEHTFHSQ	ADGRA3	981	Q8IWK6
ASHCEDPQAHTVTSD	AKAP13	706	Q12802
TVRSHAENPTASHVD	CD5	436	P06127
QFSASLHVDHSELQG	C1QTNF12	206	Q5T7M4
ANHPSAVNVLTEHSE	ARHGEF7	366	Q14155
HNHVLADDDQPSLDS	ARHGEF7	741	Q14155
HSTAAEESEHSANPT	ANKRD55	596	Q3KP44
QVSTHEQPDSAHGRT	FLG	471	P20930
NHRESVSSGETHVPN	ADCY7	501	P51828
RQFAAHPEHQSSDST	CASP12	151	Q6UXS9
SETLGVPSAAHHSVQ	DCP1A	271	Q9NPI6
NDLDDVHPSHHDTAV	ADAMTS20	341	P59510
SEPSLHRAAHTEDIN	RAF1	621	P04049
TVIAPAHHSENTTES	RBM27	241	Q9P2N5
SHHFAQADLELLASS	GPR107	456	Q5VW38
RHSQHSFLEPEASES	GSG1L2	246	A8MUP6
VADSTPAHFQTDLLH	TIPARP	151	Q7Z3E1
PHHDSSTFTLNVALN	PLOD3	666	O60568
SPATNSSHTDAHEIL	POC5	131	Q8NA72
DSHSLHGPVNDEESS	REST	526	Q13127
SSHHPADITSLHQDV	HSP90B2P	171	Q58FF3
SESSPNHSLHNEVAD	KIDINS220	1591	Q9ULH0
PSLASNASNHNSHVV	HCFC2	466	Q9Y5Z7
SSHHSSNQPASLTEE	MAGI1	941	Q96QZ7
FCLSHDESNSEPHSQ	MTUS1	311	Q9ULD2
FPSSEQLNAHVEAHV	HIC1	446	Q14526
FSPVLAQSLEHDEHS	MGRN1	341	O60291
AHSNAPITAHAEVEV	CSNK1G1	386	Q9HCP0
THDPPAAQHLSDTTN	BRSK2	636	Q8IWQ3
SHISEHPAENSLSLA	CSRNP3	551	Q8WYN3
DDSTSHSDHQDPISL	HMBOX1	376	Q6NT76
NALTVDAHTVVSHPD	PCNX3	1156	Q9H6A9
HETHADISTSQNHRP	PDZD2	1676	O15018
AATVHDVDHPGRTNS	PDE8B	651	O95263
LVTTANHSPDFDHDR	FOXP1	651	Q9H334
TSVHSQAELDFLSHN	MRC2	861	Q9UBG0
FTEATENLHHGLPAS	LCA5L	526	O95447
HVSDAPAQHAETLST	KIF26A	701	Q9ULI4
STNPAHAHFESFLQA	MICAL1	6	Q8TDZ2
SEAAAQGRETPHSHQ	GLS2	41	Q9UI32
HQLHTPATAADESPA	MPND	166	Q8N594
VHPVQQHTSSAAAAA	NLK	61	Q9UBE8
HEESSINTPAVGAAH	ARHGAP32	251	A7KAX9
EIPSTVSQHSESHTD	PNPLA7	426	Q6ZV29
AHLQTSHKPSAEDAE	NRBF2	96	Q96F24
PTASAENHTESDFHP	MFSD4B	146	Q5TF39
ENHTESDFHPALNQS	MFSD4B	151	Q5TF39
SHQTSVNADPASHEI	SMPD4	281	Q9NXE4
HSVQTFQEDSLPVAH	PTPN21	601	Q16825
HDVHNTCESSSPFQL	F2RL2	246	O00254
ASHARLISDQHADNP	OTOP2	206	Q7RTS6
STETLQHVPSDHTNE	TMEM123	51	Q8N131
DTVTDNVHHPSLFVA	PARP14	1771	Q460N5
VEDCHASEHNSPISS	KAT6A	1471	Q92794
SVALSGTNHEHDQPA	ETFDH	521	Q16134
HVNQSFGSPAEHVLS	CHD9	81	Q3L8U1
PAPEAEHSSNLTAAH	FHIP1A	731	Q05DH4
EHSSNLTAAHPESEE	FHIP1A	736	Q05DH4
TASVDSTHQEDAPSH	C2CD2	536	Q9Y426
TAVLHHSQNPDFSDE	DOCK10	731	Q96BY6
FTQDAQHSDLRDPHS	CACNA1G	696	O43497
NFNIHSSISHESPAV	CDC7	291	O00311
TSDIQGHASHQPAIS	CDC7	476	O00311
SEHHQHSDLTAPPNS	FAM193B	236	Q96PV7
SSDDVHILHPTHSQA	CDON	216	Q4KMG0
AQSSQIHDLESHSTV	CEP250	1606	Q9BV73
SSHALGESHAFSEDP	FAM120C	471	Q9NX05
ASSDHITEAFHHQPE	FAM120C	536	Q9NX05
ISPEIFHSSHQETES	CCDC66	756	A2RUB6
HFTIHTALVPSEAQD	C6orf118	111	Q5T5N4
SPDVHKSAAETSAQH	ANK3	2301	Q12955
PHTFTDSHVSEVLQE	CEP162	1161	Q5TB80
HAIHVEEQSDQSFSS	IQUB	56	Q8NA54
NAFHHPSAVRLQESD	FOXN2	276	P32314
LTAHAEESQHESTQS	KLF18	41	A0A0U1RQI7
DAVHIAPQESLADSH	EML5	601	Q05BV3
HLSLQDLSDHASSAD	RSC1A1	71	Q92681
DLSDHASSADHAPTD	RSC1A1	76	Q92681
SSINDLTDHNHDGTP	SLC15A1	101	P46059
TDSSVHAPSEITVAH	INPP5F	911	Q9Y2H2
NNTHHFHNDSITPSE	SLC39A10	191	Q9ULF5
HPCFDSSTAHQLDAA	PKD1L1	831	Q8TDX9
EDPHQHSTAAEEKTS	PRR14L	141	Q5THK1
PHLSDQSSSSSHDDV	PARD3	771	Q8TEW0
RAHGVSVQPEASDTH	NMRK2	81	Q9NPI5
TLHPDASANFHSLDD	FUT8	481	Q9BYC5
FPSSEQLNAHVETHT	HIC2	451	Q96JB3
AEEPHALELNTAHSA	SFI1	991	A8K8P3
PHTDNSSEINTTHNL	PRUNE2	1036	Q8WUY3
EHQTSDEDSVHSPSS	SYNE2	5076	Q8WXH0
SAASNSASVHHNELV	SLC22A24	446	Q8N4F4
LSSSSNADQRPHDSH	SMARCAL1	76	Q9NZC9
SQEEAAHTSGQPFHS	KIAA1217	851	Q5T5P2
NSHAEPSRADSHVKD	KIAA1217	1151	Q5T5P2
HADTGASNFVSPEHL	SHROOM3	116	Q8TF72
AASAASSAHVALQVH	SHARPIN	231	Q9H0F6
HLSSSQSHRSDPNSE	SECISBP2L	371	Q93073
VHLTANHVPAAAAAE	SCFD2	111	Q8WU76
SETQHRGSAPHSESD	SRPK1	26	Q96SB4
ATNSPDHSDHTLSVS	TNS3	376	Q68CZ2
SELQAPFHSHELSLA	TNS3	991	Q68CZ2
AHFTAASVADDQPSI	PEX12	6	O00623
SSPAAVNHHSSSDIS	PEX14	251	O75381
VNHHSSSDISPVSNE	PEX14	256	O75381
DSDHSSPFHSSNDTV	SOS1	1106	Q07889
SSLSTHHRTQDDPSF	REELD1	296	A0A1B0GV85
TSDHHLDAAAARQPN	NCKIPSD	121	Q9NZQ3
PSQTDTHQLHSEATH	SOX30	516	O94993
EVFSSHESSHEEPLQ	SSH3	561	Q8TE77
ENPSDTKEHHHQSSV	CHST15	126	Q7LFX5
ISNDDDSASPLHHIS	NTRK2	471	Q16620
DIPHSSSDSTIHENL	RLF	1826	Q13129
HSHESLLSPSSAAEA	SYNGAP1	181	Q96PV0
AQNLHDESLSTSPHG	GTF2A1L	271	Q9UNN4
EDGTISSNATHVEHP	STARD5	126	Q9NSY2
ATPNHVEHTLSVSSD	TNS1	391	Q9HBL0
TFHVDSEHPNVVLNS	ZHX1	86	Q9UKY1
EISSDSHAPLHSVTN	ZDBF2	871	Q9HCK1
AHSHLEQQQSHETAP	TANGO6	791	Q9C0B7
SDVTGNHAALHRDPS	TTC3	1761	P53804
QHRAALAHSEEVTAS	PLEC	2741	Q15149
QADTPAGLAHSTHVT	RIOX2	241	Q8IUF8
HHSSPTSEAEEFVSR	UNC5A	411	Q6ZN44
EFVHHDENHSSPSAE	PLEKHA3	136	Q9HB20
NHPETHTLVSKASDF	ZNFX1	1266	Q9P2E3
HVASAHLAIDSTADP	SLC30A3	331	Q99726
EELHLATSTSDPAQH	ZBTB24	656	O43167
SHQALHAARDDDFPS	ZNF598	881	Q86UK7
DDFVLVPHNISSDHS	ULK2	351	Q8IYT8
NALHTSAHSTEESLP	ZCCHC14	71	Q8WYQ9
LLQEHSAQHSAAAAA	ZNF319	556	Q9P2F9
HQAFLHASESAQPSE	TBC1D5	221	Q92609
HSQHSEASQGPLSLD	C16orf82	51	Q7Z2V1
DTQSSESHVSSVQHP	C16orf82	126	Q7Z2V1
DAPITSLHEAHEFSN	PC	171	P11498
LESREAHHSNTHSPE	ZNF318	676	Q5VUA4
FNSHESAAHAIVSVN	TIA1	256	P31483
HFSLHITETQPEDSA	TRAV13-1	91	A0A0B4J241
LNDTSAPHLENSGHT	KCNA4	351	P22459
VHSALDSDEQSHQAV	MYO1G	241	B0I1T2