Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyCellularComponentHAUS complex

HAUS5 HAUS2

1.95e-048562GO:0070652
MousePhenoincreased nucleated erythrocyte cell number

SOCS3 IKZF1 MED1 MYB

1.38e-0547444MP:0009395
MousePhenoabnormal nucleated erythrocyte cell number

SOCS3 IKZF1 MED1 MYB

1.63e-0549444MP:0012397
DomainSANT

MIS18BP1 SMARCA1 MYB

4.29e-0450553SM00717
DomainLaminin_G_1

LAMA2 EGFLAM

4.60e-0411552PF00054
DomainSANT/Myb

MIS18BP1 SMARCA1 MYB

4.82e-0452553IPR001005
Domainfn3

EGFLAM MYOM2 IL6R CDON

1.32e-03162554PF00041
Domain-

SACS TOP2B

1.56e-03205523.30.565.10
DomainHATPase_C

SACS TOP2B

1.72e-0321552IPR003594
DomainFN3

EGFLAM MYOM2 IL6R CDON

2.14e-03185554SM00060
DomainSANT_dom

MIS18BP1 SMARCA1

2.64e-0326552IPR017884
DomainFN3

EGFLAM MYOM2 IL6R CDON

2.79e-03199554PS50853
DomainSANT

MIS18BP1 SMARCA1

3.06e-0328552PS51293
DomainIG_LIKE

CD1E MXRA5 MYOM2 IL6R CD300C CDON

3.12e-03491556PS50835
Domain-

CD1E MXRA5 EGFLAM MYOM2 IL6R CD300C CDON

3.18e-036635572.60.40.10
DomainFN3_dom

EGFLAM MYOM2 IL6R CDON

3.33e-03209554IPR003961
DomainIg-like_dom

CD1E MXRA5 MYOM2 IL6R CD300C CDON

3.51e-03503556IPR007110
DomainIg-like_fold

CD1E MXRA5 EGFLAM MYOM2 IL6R CD300C CDON

4.49e-03706557IPR013783
DomainMyb_DNA-binding

MIS18BP1 MYB

4.76e-0335552PF00249
DomainIGc2

MXRA5 MYOM2 IL6R CDON

5.04e-03235554SM00408
DomainIg_sub2

MXRA5 MYOM2 IL6R CDON

5.04e-03235554IPR003598
DomainMYB_LIKE

MIS18BP1 MYB

5.59e-0338552PS50090
DomainLAM_G_DOMAIN

LAMA2 EGFLAM

5.59e-0338552PS50025
DomainLaminin_G_2

LAMA2 EGFLAM

6.18e-0340552PF02210
DomainLamG

LAMA2 EGFLAM

7.44e-0344552SM00282
DomainIG

MXRA5 MYOM2 IL6R CD300C CDON

7.84e-03421555SM00409
PathwayBIOCARTA_VDR_PATHWAY

MED1 TOP2B VDR

4.79e-0522463MM1370
PathwayBIOCARTA_VDR_PATHWAY

MED1 TOP2B VDR

6.27e-0524463M13404
Pubmed

The TRAP220 component of a thyroid hormone receptor- associated protein (TRAP) coactivator complex interacts directly with nuclear receptors in a ligand-dependent fashion.

MED24 MED1 VDR

4.97e-07105739653119
Pubmed

Analyses of shared genetic factors between asthma and obesity in children.

DGKG RASAL2 MYB VDR

1.10e-064757420816195
Pubmed

Double knockout of vitamin D receptor and its coactivator mediator complex subunit 1 unexpectedly enhances epidermal permeability barrier function in mice.

MED1 VDR

2.64e-06257234453978
Pubmed

Vitamin D receptor rs2228570 polymorphism and invasive ovarian carcinoma risk: pooled analysis in five studies within the Ovarian Cancer Association Consortium.

MED1 VDR

2.64e-06257220473893
Pubmed

Ligand-dependent transcription activation by nuclear receptors requires the DRIP complex.

MED24 MED1 VDR

2.79e-061757310235266
Pubmed

Identity between TRAP and SMCC complexes indicates novel pathways for the function of nuclear receptors and diverse mammalian activators.

MED24 MED1 VDR

3.35e-061857310198638
Pubmed

An ARC/Mediator subunit required for SREBP control of cholesterol and lipid homeostasis.

MED24 MED1 MYB

3.97e-061957316799563
Pubmed

The Expression of Inflammasomes NLRP1 and NLRP3, Toll-Like Receptors, and Vitamin D Receptor in Synovial Fibroblasts From Patients With Different Types of Knee Arthritis.

NLRP1 VDR

7.91e-06357235126351
Pubmed

Transcriptional control of B cell development and function.

IKZF1 MYB

7.91e-06357214960357
Pubmed

IL-17 enhancement of the IL-6 signaling cascade in astrocytes.

SOCS3 IL6R

7.91e-06357220351184
Pubmed

The transcriptional coactivator DRIP/mediator complex is involved in vitamin D receptor function and regulates keratinocyte proliferation and differentiation.

MED1 VDR

7.91e-06357220520624
Pubmed

Differential role of two VDR coactivators, DRIP205 and SRC-3, in keratinocyte proliferation and differentiation.

MED1 VDR

7.91e-06357217223341
Pubmed

The vitamin D receptor interacts preferentially with DRIP205-like LxxLL motifs.

MED1 VDR

7.91e-06357217254542
Pubmed

Regulation of human epidermal keratinocyte differentiation by the vitamin D receptor and its coactivators DRIP205, SRC2, and SRC3.

MED1 VDR

7.91e-06357217082781
Pubmed

Molecular determinants of MED1 interaction with the DNA bound VDR-RXR heterodimer.

MED1 VDR

7.91e-06357232990725
Pubmed

A novel mutation in helix 12 of the vitamin D receptor impairs coactivator interaction and causes hereditary 1,25-dihydroxyvitamin D-resistant rickets without alopecia.

MED1 VDR

7.91e-06357212403843
Pubmed

Mediator subunits MED1 and MED24 cooperatively contribute to pubertal mammary gland development and growth of breast carcinoma cells.

MED24 MED1

7.91e-06357222331469
Pubmed

Phosphorylation of the human retinoid X receptor alpha at serine 260 impairs coactivator(s) recruitment and induces hormone resistance to multiple ligands.

MED1 VDR

7.91e-06357218003614
Pubmed

Spatial intratumoral heterogeneity and temporal clonal evolution in esophageal squamous cell carcinoma.

ZNF750 KMT2D

7.91e-06357227749841
Pubmed

Elevated maternal soluble Gp130 and IL-6 levels and reduced Gp130 and SOCS-3 expressions in women complicated with preeclampsia.

SOCS3 IL6R

7.91e-06357221173340
Pubmed

Deficiency of merosin in dystrophic dy mice and genetic linkage of laminin M chain gene to dy locus.

LAMA2 MYB

1.58e-0545728188645
Pubmed

epicardin: A novel basic helix-loop-helix transcription factor gene expressed in epicardium, branchial arch myoblasts, and mesenchyme of developing lung, gut, kidney, and gonads.

LAMA2 MYB

1.58e-0545729733105
Pubmed

1alpha,25-dihydroxy vitamin D3-enhanced expression of the osteocalcin gene involves increased promoter occupancy of basal transcription regulators and gradual recruitment of the 1alpha,25-dihydroxy vitamin D3 receptor-SRC-1 coactivator complex.

MED1 VDR

1.58e-05457217786964
Pubmed

The DRIP complex and SRC-1/p160 coactivators share similar nuclear receptor binding determinants but constitute functionally distinct complexes.

MED1 VDR

1.58e-05457210733574
Pubmed

Binding of liganded vitamin D receptor to the vitamin D receptor interacting protein coactivator complex induces interaction with RNA polymerase II holoenzyme.

MED1 VDR

2.63e-05557210753860
Pubmed

2-Methylene-19-nor-(20S)-1,25-dihydroxyvitamin D3 potently stimulates gene-specific DNA binding of the vitamin D receptor in osteoblasts.

MED1 VDR

2.63e-05557212796488
Pubmed

Regulation of the human p21(waf1/cip1) gene promoter via multiple binding sites for p53 and the vitamin D3 receptor.

MED1 VDR

2.63e-05557216434701
Pubmed

Genome-wide association and linkage study in the Amish detects a novel candidate late-onset Alzheimer disease gene.

LUZP2 CDON

3.94e-05657222881374
Pubmed

Localisation of a dystrophin-related autosomal gene to 6q24 in man, and to mouse chromosome 10 in the region of the dystrophia muscularis (dy) locus.

LAMA2 MYB

3.94e-0565722203673
Pubmed

SOCS3 exerts its inhibitory function on interleukin-6 signal transduction through the SHP2 recruitment site of gp130.

SOCS3 IL6R

3.94e-05657210777583
Pubmed

Association analysis of TNFR2, VDR, A2M, GSTT1, GSTM1, and ACE genes with rheumatoid arthritis in South Asians and Caucasians of East Midlands in the United Kingdom.

A2M VDR

3.94e-05657220401725
Pubmed

Activation of Akt/PDK signaling in macrophages upon binding of receptor-recognized forms of alpha2-macroglobulin to its cellular receptor: effect of silencing the CREB gene.

A2M PDPK1

3.94e-05657215389876
Pubmed

Spatio-temporal activation of chromatin on the human CYP24 gene promoter in the presence of 1alpha,25-Dihydroxyvitamin D3.

MED1 VDR

3.94e-05657215919092
Pubmed

Polyamines modulate the interaction between nuclear receptors and vitamin D receptor-interacting protein 205.

MED1 VDR

3.94e-05657212089346
Pubmed

Augmin: a protein complex required for centrosome-independent microtubule generation within the spindle.

HAUS5 HAUS2

3.94e-05657218443220
Pubmed

Temporal formation of distinct thyroid hormone receptor coactivator complexes in HeLa cells.

MED24 MED1

5.51e-05757211117530
Pubmed

Activated α2-macroglobulin binding to cell surface GRP78 induces T-loop phosphorylation of Akt1 by PDK1 in association with Raptor.

A2M PDPK1

5.51e-05757224516643
Pubmed

Common architecture of nuclear receptor heterodimers on DNA direct repeat elements with different spacings.

MED1 VDR

5.51e-05757221478865
Pubmed

The TRAP100 component of the TRAP/Mediator complex is essential in broad transcriptional events and development.

MED24 MED1

5.51e-05757212093747
Pubmed

Multiple genetic variants along candidate pathways influence plasma high-density lipoprotein cholesterol concentrations.

ACACA MBTPS2 PDPK1 SOCS3 MED1

5.69e-0525057518660489
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

MED24 KMT2D DOCK8 TNPO2 IKZF1 MED1 TOP2B PRRC2B MYB

7.19e-05110357934189442
Pubmed

HAUS, the 8-subunit human Augmin complex, regulates centrosome and spindle integrity.

HAUS5 HAUS2

7.34e-05857219427217
Pubmed

The HAUS Complex Is a Key Regulator of Non-centrosomal Microtubule Organization during Neuronal Development.

HAUS5 HAUS2

7.34e-05857230044976
Pubmed

Zac1 (Lot1), a potential tumor suppressor gene, and the gene for epsilon-sarcoglycan are maternally imprinted genes: identification by a subtractive screen of novel uniparental fibroblast lines.

LAMA2 MYB

7.34e-05857210757814
Pubmed

Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.

MED24 KMT2D PHF3 MED1 PRRC2B

7.90e-0526857533640491
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

EXOC6 KMT2D MXRA5 DDHD1 MED1 RASAL2 PRRC2B

8.08e-0563857731182584
Pubmed

The transcriptional cofactor complex CRSP is required for activity of the enhancer-binding protein Sp1.

MED24 MED1

9.43e-0595729989412
Pubmed

TRAP/SMCC/mediator-dependent transcriptional activation from DNA and chromatin templates by orphan nuclear receptor hepatocyte nuclear factor 4.

MED24 MED1

9.43e-05957212101254
Pubmed

Ligand induction of a transcriptionally active thyroid hormone receptor coactivator complex.

MED24 MED1

9.43e-0595728710870
Pubmed

A coregulatory role for the TRAP-mediator complex in androgen receptor-mediated gene expression.

MED24 MED1

1.18e-041057212218053
Pubmed

Trans-presentation of IL-6 by dendritic cells is required for the priming of pathogenic TH17 cells.

SOCS3 IL6R

1.44e-041157227893700
Pubmed

The microtubule-associated protein EML3 regulates mitotic spindle assembly by recruiting the Augmin complex to spindle microtubules.

HAUS5 HAUS2

1.44e-041157230723163
Pubmed

The augmin complex plays a critical role in spindle microtubule generation for mitotic progression and cytokinesis in human cells.

HAUS5 HAUS2

1.44e-041157219369198
Pubmed

Transcriptional regulation of SPROUTY2 by MYB influences myeloid cell proliferation and stem cell properties by enhancing responsiveness to IL-3.

SOCS3 MYB

1.44e-041157227748374
Pubmed

An investigation into the human serum "interactome".

EXOC6 SACS DGKG NLRP1

1.48e-0416257415174051
Pubmed

Telencephalic embryonic subtractive sequences: a unique collection of neurodevelopmental genes.

COL8A1 MIS18BP1 TNPO2 CDON

1.59e-0416557416107646
Pubmed

Investigation of genetic susceptibility factors for human longevity - a targeted nonsynonymous SNP study.

A2M GALNT8 NLRP1 IL6R TOP2B

1.63e-0431357520800603
Pubmed

Follistatin regulates the specification of the apical cochlea responsible for low-frequency hearing in mammals.

A2M SLITRK3

1.72e-041257236577057
Pubmed

Identification of a transcriptionally active peroxisome proliferator-activated receptor alpha -interacting cofactor complex in rat liver and characterization of PRIC285 as a coactivator.

MED24 MED1

1.72e-041257212189208
Pubmed

MED1 phosphorylation promotes its association with mediator: implications for nuclear receptor signaling.

MED24 MED1

1.72e-041257218391015
Pubmed

Vitamin D-related genes, serum vitamin D concentrations and prostate cancer risk.

MED1 VDR

2.03e-041357219255064
Pubmed

Loss of Dnmt3b accelerates MLL-AF9 leukemia progression.

PDPK1 MYB

2.03e-041357227133822
Pubmed

Rubella vaccine-induced cellular immunity: evidence of associations with polymorphisms in the Toll-like, vitamin A and D receptors, and innate immune response genes.

TOP2B VDR

2.37e-041457219902255
Pubmed

A novel human SRB/MED-containing cofactor complex, SMCC, involved in transcription regulation.

MED24 MED1

2.37e-041457210024883
Pubmed

The laminin alpha chains: expression, developmental transitions, and chromosomal locations of alpha1-5, identification of heterotrimeric laminins 8-11, and cloning of a novel alpha3 isoform.

LAMA2 MYB

2.37e-04145729151674
Pubmed

Transcriptional map of chromosome region 6q16-->q21.

LAMA2 MYB

2.37e-041457210575223
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

MED24 KMT2D ACACA PHF3 PDPK1 MED1 TOP2B

2.65e-0477457715302935
Pubmed

Cooperative activity of cdk8 and GCN5L within Mediator directs tandem phosphoacetylation of histone H3.

MED24 MED1

2.73e-041557218418385
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

KMT2D ACACA PHF3 HAUS5 MED1 PRRC2B

2.76e-0454957638280479
Pubmed

Transcriptome-based systematic identification of extracellular matrix proteins.

COL8A1 LAMA2 EGFLAM

3.02e-047957318757743
Pubmed

The USA-derived transcriptional coactivator PC2 is a submodule of TRAP/SMCC and acts synergistically with other PCs.

MED24 MED1

3.12e-041657210882111
Pubmed

Comprehensive proteomic characterization of stem cell-derived extracellular matrices.

A2M COL8A1 MXRA5

3.88e-048657328327460
Pubmed

The contribution of de novo coding mutations to autism spectrum disorder.

DIP2A PHF3

3.97e-041857225363768
Pubmed

Acetylation of poly(ADP-ribose) polymerase-1 by p300/CREB-binding protein regulates coactivation of NF-kappaB-dependent transcription.

MED24 MED1

4.43e-041957216204234
Pubmed

Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity.

DGKG RASAL2

4.92e-042057219079260
Pubmed

Structural and functional organization of TRAP220, the TRAP/mediator subunit that is targeted by nuclear receptors.

MED24 MED1

4.92e-042057215340084
Pubmed

Transcriptome profiling of mouse brain and lung under Dip2a regulation using RNA-sequencing.

DIP2A VDR

4.92e-042057231291246
Pubmed

Hematopoietic growth factor receptor genes as markers of lineage commitment during in vitro development of hematopoietic cells.

IL6R MYB

5.43e-04215728499630
Pubmed

Phospho-tyrosine dependent protein-protein interaction network.

TRIT1 PDPK1 SOCS3 PRRC2B POLR3F

5.62e-0441057525814554
Pubmed

DDB1 binds histone reader BRWD3 to activate the transcriptional cascade in adipogenesis and promote onset of obesity.

MED24 SMARCA1 MED1

5.86e-049957334161765
Pubmed

The TRAP/Mediator coactivator complex interacts directly with estrogen receptors alpha and beta through the TRAP220 subunit and directly enhances estrogen receptor function in vitro.

MED24 MED1

5.97e-042257211867769
Pubmed

Characterization of definitive lymphohematopoietic stem cells in the day 9 murine yolk sac.

IL6R MYB

5.97e-04225729324354
Pubmed

AML1(-/-) embryos do not express certain hematopoiesis-related gene transcripts including those of the PU.1 gene.

IKZF1 MYB

5.97e-04225729811459
Pubmed

Scl represses cardiomyogenesis in prospective hemogenic endothelium and endocardium.

IKZF1 MYB

5.97e-042257222863011
Pubmed

Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

RALGAPA1 HAUS5 SLITRK3

6.03e-0410057310048485
Pubmed

Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.

A2M MED24 MIS18BP1 HAUS5 MED1 HAUS2

6.46e-0464557625281560
Pubmed

Composite co-activator ARC mediates chromatin-directed transcriptional activation.

MED24 MED1

6.53e-042357210235267
Pubmed

Human Immunodeficiency Virus Type 1 Vpr Mediates Degradation of APC1, a Scaffolding Component of the Anaphase-Promoting Complex/Cyclosome.

MED24 ACACA HAUS5 PRRC2B

6.76e-0424257434011540
Pubmed

The nuclear interactome of DYRK1A reveals a functional role in DNA damage repair.

RALGAPA1 KMT2D HAUS2

7.14e-0410657331024071
Pubmed

ATAC and Mediator coactivators form a stable complex and regulate a set of non-coding RNA genes.

MED24 MED1 PRRC2B

7.34e-0410757320508642
Pubmed

Holoprosencephaly Overview

KMT2D CDON

7.73e-042557220301702
Pubmed

Colon tumor mutations and epigenetic changes associated with genetic polymorphism: insight into disease pathways.

NAT2 VDR

7.73e-042557218992263
Pubmed

Human Antiviral Protein IFIX Suppresses Viral Gene Expression during Herpes Simplex Virus 1 (HSV-1) Infection and Is Counteracted by Virus-induced Proteasomal Degradation.

PHF3 EGFLAM TOP2B PRRC2B

7.75e-0425157428077445
Pubmed

Subunit architecture and functional modular rearrangements of the transcriptional mediator complex.

MED24 MED1

8.36e-042657224882805
Pubmed

Novel critical role of a human Mediator complex for basal RNA polymerase II transcription.

MED24 MED1

8.36e-042657211559591
Pubmed

Mediator complex proximal Tail subunit MED30 is critical for Mediator core stability and cardiomyocyte transcriptional network.

MED24 MED1

8.36e-042657234506481
Pubmed

Genome-Wide Mapping and Interrogation of the Nmp4 Antianabolic Bone Axis.

IGFBP4 PDPK1

8.36e-042657226244796
Pubmed

The protein interaction landscape of the human CMGC kinase group.

A2M MED24 PHF3 PDPK1 MED1 VDR

9.52e-0469557623602568
Pubmed

Mediator and cohesin connect gene expression and chromatin architecture.

MED24 MED1

9.71e-042857220720539
Pubmed

A mammalian mediator subunit that shares properties with Saccharomyces cerevisiae mediator subunit Cse2.

MED24 MED1

1.04e-032957214638676
Cytoband6q22-q23

LAMA2 MYB

7.01e-05105826q22-q23
GeneFamilyHAUS augmin like complex

HAUS5 HAUS2

1.26e-048392581
GeneFamilyGATA zinc finger domain containing|Myb/SANT domain containing

MIS18BP1 SMARCA1 MYB

2.02e-0453393532
GeneFamilyImmunoglobulin like domain containing

MXRA5 MYOM2 IL6R CDON

7.73e-04193394594
GeneFamilyCyclins|Mediator complex

MED24 MED1

2.29e-03333921061
GeneFamilyFibronectin type III domain containing

EGFLAM MYOM2 CDON

4.92e-03160393555
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

MXRA5 MYOM2 CDON

5.01e-03161393593
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

SACS IKZF1 VDR

6.92e-03181393694
CoexpressionBUSSLINGER_GASTRIC_IMMUNE_CELLS

RALGAPA1 ARHGAP4 DIP2A KMT2D MIS18BP1 SACS DOCK8 PHF3 RBMS1 NLRP1 IKZF1 MED1 TOP2B PRRC2B

2.69e-0614925714M40023
CoexpressionDUAN_PRDM5_TARGETS

SOCS3 MYOM2 IL6R MYB

2.42e-0577574M2339
CoexpressionLAKE_ADULT_KIDNEY_C28_INTERSTITIUM

A2M RBMS1 LAMA2 RASAL2

3.74e-0586574M39247
CoexpressionLAKE_ADULT_KIDNEY_C26_MESANGIAL_CELLS

A2M DOCK8 RBMS1 LAMA2 RASAL2

4.18e-05177575M39245
CoexpressionZHONG_PFC_MAJOR_TYPES_MICROGLIA

A2M ARHGAP4 MIS18BP1 DOCK8 RBMS1 IKZF1 IL6R

4.46e-05438577M39077
CoexpressionVERRECCHIA_RESPONSE_TO_TGFB1_C6

COL8A1 IGFBP4

4.63e-055572M15374
CoexpressionDESCARTES_FETAL_STOMACH_MESOTHELIAL_CELLS

BNC1 COL8A1 CDON

7.19e-0537573M40310
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

A2M DOCK8 RBMS1 LAMA2 DGKG SLITRK3

6.16e-081595865ca96db4281abb5f646150ccf36adc66ab201c78
ToppCellPCW_13-14-Hematologic_Myeloid-Hem_Myeloid_dendritic-im_conventional_dendritic_(19)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

CD1E DOCK8 IKZF1 IL6R VDR CCSER1

1.24e-071795869fc44637c9a7551fd47b8533e45a9c199e164a95
ToppCellPCW_13-14-Hematologic_Myeloid-Hem_Myeloid_dendritic-im_dendritic_(11)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

CD1E DOCK8 IKZF1 IL6R CD300C VDR

1.71e-07189586911bedfda2ae032bc8f18ee408d16926cda8ccc2
ToppCellPCW_13-14-Hematologic_Myeloid-Hem_Myeloid_dendritic|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

CD1E DOCK8 IKZF1 IL6R CD300C VDR

1.82e-0719158603e1ac489e918c7affc1cdc09fb3eb255bcf80e5
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

A2M COL8A1 MXRA5 IGFBP4 LAMA2 CACNA1G

2.39e-0720058658b38f9a484ee94191091a0659ed62ebed2d4a14
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

A2M DOCK8 RBMS1 LAMA2 DGKG

2.83e-06170585876b84740e15399bfff2b9c7f0b80fd759bbdb3f
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

A2M DOCK8 RBMS1 LAMA2 DGKG

2.83e-061705851f8738acf439d893880db7e1fdc9b3615ca00c39
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-SMC_prolif|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MXRA5 RNF152 IGFBP4 LAMA2 EGFLAM

3.74e-0618058564956a85c404a2ea7e4eaf6f95ebcc52c198b7cc
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Pericyte-A|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MXRA5 RNF152 IGFBP4 LAMA2 EGFLAM

3.95e-06182585fc4a5bf784705efe7965ce43ac23c2a8e602e90a
ToppCell5'-Adult-Distal_Rectal-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IGFBP4 LAMA2 SLITRK3 EGFLAM CDON

4.28e-061855859faa35ceb89ccd2979072286f063687c9f846ce3
ToppCell3'-GW_trimst-1-LargeIntestine-Hematopoietic-Myeloid-cDC2|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CD1E DOCK8 IKZF1 IL6R CD300C

4.28e-06185585e592c27f711d13bfc6546893acaab4c8600b0be1
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

A2M RBMS1 SMARCA1 LAMA2 DGKG

4.51e-06187585d591a3c216997663ab77710fed0d230ffc37e41a
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

A2M RBMS1 SMARCA1 LAMA2 DGKG

4.51e-06187585d1dc8c9a2c2cd10c640257161a75e7730ec5bb41
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

A2M RBMS1 SMARCA1 LAMA2 DGKG

4.51e-06187585ac8e092b37e042975e2ee057d3f7c6821e58e8b5
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

A2M RBMS1 LAMA2 DGKG SLITRK3

4.51e-0618758515d6e158562d7d85af3ceaf955439b379c8fce81
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

A2M RBMS1 LAMA2 DGKG SLITRK3

4.51e-06187585f62074b631fd45ad299c69d71b09267b04d656ee
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

A2M RBMS1 LAMA2 DGKG SLITRK3

4.62e-0618858532f22a4d8cb98fd8b8fa0fbf28ef9266d711d081
ToppCellPCW_10-12-Hematologic_Myeloid-Hem_Myeloid_dendritic-im_dendritic_(11)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

CD1E DOCK8 IKZF1 CD300C VDR

4.87e-06190585eda2923e930e1094412088fd79c1e6a3b7db3b11
ToppCellPCW_10-12-Hematologic_Myeloid-Hem_Myeloid_dendritic|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

DOCK8 IKZF1 IL6R CD300C VDR

4.99e-06191585a5ee4d72b2311c8fa98ff73adc2499debb2014f1
ToppCell5'-Adult-LymphNode-Mesenchymal|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MXRA5 IGFBP4 SOCS3 LAMA2 EGFLAM

4.99e-06191585054e9a79bd1486fd812bc7418fb091664fe3a646
ToppCell5'-Adult-LymphNode-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MXRA5 IGFBP4 SOCS3 LAMA2 EGFLAM

5.12e-061925859479e9859140ba98abfe88414de0b28fc2bf43b7
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Pericyte|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MXRA5 RNF152 IGFBP4 LAMA2 EGFLAM

5.12e-0619258509cb5b89a164ac7444774ccc8c90323c8ea2026b
ToppCell5'-Adult-LymphNode-Mesenchymal-fibroblastic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MXRA5 IGFBP4 SOCS3 LAMA2 EGFLAM

5.12e-06192585d7faa993f68e530ad55185505384ae155d36c222
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MXRA5 RNF152 IGFBP4 LAMA2 EGFLAM

5.25e-06193585dd4bac8a93a5b9dcf7301f1d7d6e3eb6670f5c68
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Vascular|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MXRA5 RNF152 IGFBP4 LAMA2 EGFLAM

5.25e-061935852ddf9b2770a0be9689e01d1a3d19e4a6d42c7a50
ToppCelldistal-2-Hematologic-Myeloid_Dendritic_Type_2|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CD1E SACS IL6R VDR CCSER1

5.39e-061945856881cfe12837a32e598535a564e4c31d4846167b
ToppCelldistal-Hematologic-Myeloid_Dendritic_Type_2-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CD1E SACS IL6R VDR CCSER1

5.52e-061955857606b8b40e704bb5447ac57ccf8698794e9c7890
ToppCell3'-GW_trimst-1-LargeIntestine-Hematopoietic-Myeloid-LYVE1+_Macrophage|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

A2M ARHGAP4 DOCK8 IKZF1 IL6R

5.52e-06195585c14d730dd5c94247bc09711eaa5a53bd5a5957be
ToppCell5'-GW_trimst-1.5-SmallIntestine-Hematopoietic-Myeloid-cDC2|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ARHGAP4 CD1E DOCK8 IKZF1 IL6R

5.52e-0619558597a9410f47beca02346902d078288a75bfe6e56b
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Scavenging_pericyte|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MXRA5 RNF152 IGFBP4 LAMA2 EGFLAM

5.66e-06196585cb61757646653f89faba503cb5d99e5dd5197b4c
ToppCellIPF-Stromal-Myofibroblast|World / Disease state, Lineage and Cell class

A2M COL8A1 MXRA5 IGFBP4 LAMA2

5.66e-061965857fc9894ceb79dab9f0495acc84e2d6d0d1c69bb7
ToppCellIPF-Stromal-Myofibroblast|IPF / Disease state, Lineage and Cell class

A2M COL8A1 MXRA5 IGFBP4 LAMA2

5.66e-061965852d0a48e49b3b37bb66e33e74c52915911e1f8a74
ToppCell3'-GW_trimst-1-SmallIntestine-Hematopoietic-Myeloid-cDC2|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CD1E DOCK8 IKZF1 IL6R CD300C

5.66e-06196585a692cee9254f3771a076b290688a4d0120c02c3b
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Scavenging_pericyte-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MXRA5 RNF152 IGFBP4 LAMA2 EGFLAM

5.66e-0619658544e2df1b61e3819eae7e482bef0a733afe852d67
ToppCell3'-GW_trimst-1-SmallIntestine-Hematopoietic-Myeloid-LYVE1+_Macrophage|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

A2M ARHGAP4 DOCK8 IKZF1 IL6R

5.81e-06197585759f26753f76af3ae8d8527c4d221206245a3d45
ToppCelltumor_Lung-Fibroblasts-COL14A1+_matrix_FBs|tumor_Lung / Location, Cell class and cell subclass

A2M COL8A1 MXRA5 IGFBP4 LAMA2

5.95e-0619858574f2c7ef702b25a5b99e56121229e678ed992524
ToppCellmild-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

A2M RALGAPA1 DIP2A PHF3 DDHD1

6.10e-06199585f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCellTracheal-10x3prime_v2-Stromal-Fibroblastic-Fibro_peribronchial|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

A2M COL8A1 MXRA5 LAMA2 LUZP2

6.10e-06199585e9009eee7f77b9c9917f8e0e723001d9e76eb553
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW26-Mesenchymal-BMP_responsible_cell|GW26 / Sample Type, Dataset, Time_group, and Cell type.

A2M DOCK8 RBMS1 IKZF1 IL6R

6.25e-06200585cd0d69f973ca3204b500d12031b403a1f4593431
ToppCell11.5-Airway-Immune|Airway / Age, Tissue, Lineage and Cell class

ARHGAP4 DOCK8 IKZF1 IL6R CD300C

6.25e-062005852969515fa33d911e4eb55634fa2846f68a9f7896
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW26-Mesenchymal|GW26 / Sample Type, Dataset, Time_group, and Cell type.

A2M DOCK8 RBMS1 IKZF1 IL6R

6.25e-0620058516caefcc5bdca82d904462c6fd0ffa80d96fa474
ToppCelltumor_Lung-Fibroblasts|tumor_Lung / Location, Cell class and cell subclass

A2M COL8A1 MXRA5 IGFBP4 LAMA2

6.25e-06200585073a68b5ce232203ffee86342cba2a00d907e119
ToppCellParenchymal-10x5prime-Stromal-Pericyte-Muscle_pericyte_pulmonary|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

A2M RNF152 LAMA2 DGKG EGFLAM

6.25e-06200585f9bc22ff17bb1c751e6b05bca3f403836f33459a
ToppCellParenchymal-10x5prime-Stromal-Pericyte|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

A2M RNF152 LAMA2 DGKG EGFLAM

6.25e-062005850a7640db28c708003d5da2d19eb651f6fedfd710
ToppCell367C-Fibroblasts|367C / Donor, Lineage, Cell class and subclass (all cells)

A2M COL8A1 MXRA5 IGFBP4 LAMA2

6.25e-06200585c5aaa20c59b9f11b8abdf5de9e3fc54f4e6e39f7
ToppCellBronchial_Biopsy-Mesenchymal-Fibroblasts|Mesenchymal / Tissue, Lineage and Cell class of Lung Cells from 10X

A2M COL8A1 MXRA5 LAMA2

2.43e-0512958413cd10ffdd8f1ef7721884e9efd2cf25f170f414
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Myeloid-Dendritic-conventional_dendritic_cell-DC_c1-CLEC9A|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

A2M CD1E IGFBP4 DGKG

4.97e-05155584d76a0f99ec35560d18820f9c92b69364ef2250e3
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-SMC_prolif-A|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MXRA5 IGFBP4 LAMA2 EGFLAM

5.36e-0515858432c95c1bc9e50fccd6d06e828f29258fc5e568cb
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-high_Fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

A2M COL8A1 LAMA2 SLITRK3

5.49e-05159584e812cbde59188924c6277c3feadf1a9592fa62a4
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-high_Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

A2M COL8A1 LAMA2 SLITRK3

5.49e-051595842607b562903228274fbd96168ba826782fab0b53
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell-Renin-positive_Juxtaglomerular_Granular_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

A2M DGKG EGFLAM MYOM2

5.91e-05162584c7114e24cb5525abb9780ca3d35dbcc4eabd4b64
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

A2M DGKG EGFLAM MYOM2

5.91e-05162584f1851a173d3bcca2981d934161ec85d1cc0af5a2
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

A2M DGKG EGFLAM MYOM2

5.91e-051625845d902bb31e691aea9749617cc88303c2448f24b8
ToppCellTCGA-Uterus-Primary_Tumor-Uterine_Carcinoma-Uterine_Carcinosarcoma-3|TCGA-Uterus / Sample_Type by Project: Shred V9

ZNF750 CD1E RNF152 DOCK8

6.05e-05163584d64dd39b077105c73e570ccef70f0e74a2c586ac
ToppCellAdult-Mesenchymal-chondrocyte-D231|Adult / Lineage, Cell type, age group and donor

A2M MXRA5 SOCS3 LAMA2

6.19e-051645842ba57dce5f69a88f0d1e450b9780425e2d9ca7d4
ToppCellFetal_29-31_weeks-Immune-dendritic_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CD1E DOCK8 IKZF1 CCSER1

6.34e-05165584d8b0a9b6f704b98e8f0412c11739879a26c036e2
ToppCellLV-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

A2M DOCK8 DGKG EGFLAM

6.34e-05165584f37fd95adc95d7753cf6e55ae819976513c7ec77
ToppCellPBMC-Severe-Myeloid-cDC-cDC-cDC_0|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CD1E RASAL2 CD300C CCSER1

7.12e-051705847bba77ae34a0259fad6ee98cf665ff50f77a1328
ToppCellPBMC-Severe-Myeloid-cDC-cDC-cDC_0|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CD1E RASAL2 CD300C CCSER1

7.12e-05170584a43b977a7fe745536cf96b7c080397d9fa73086b
ToppCellControl-Fibroblasts-Pericytes|Control / group, cell type (main and fine annotations)

RNF152 LAMA2 DGKG EGFLAM

7.28e-05171584080003f698f867935c2bfc55d241d3650f45a0ab
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

A2M COL8A1 LAMA2 EGFLAM

7.28e-051715842a34685f7d83d1cf9a88d304173cbca868c5f9fd
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Monocytic-Monocyte-derived_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CD1E DOCK8 IKZF1 MYB

7.45e-05172584f6b4754a7e4b3e38030316a0ae00d932bfa87e41
ToppCell5'-GW_trimst-1.5-SmallIntestine-Hematopoietic-B_cells-CLP|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DOCK8 IKZF1 MYB VDR

8.14e-05176584f163cc6d632112aad35a0a9217c6c99fbdd1386e
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

A2M COL8A1 LAMA2 RASAL2

8.14e-051765849bc87cd5cda2372e1bce94c9dfd408eb1dfd8d0c
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-DC-cDC2-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CD1E MIS18BP1 VDR CCSER1

8.14e-05176584a31d7532f8c055d4e62bbaa78d819f2495bfee00
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

A2M COL8A1 LAMA2 RASAL2

8.14e-051765843f8274a7ab67f9f8a8923193763a5543cfe4defa
ToppCell356C-Fibroblasts-Fibroblast-C_(Myofibroblast)-|356C / Donor, Lineage, Cell class and subclass (all cells)

A2M COL8A1 MXRA5 LAMA2

8.32e-05177584cdfd2f0ee2f692271b1525e414b0f645cdadb1f6
ToppCell3'-Adult-SmallIntestine-Hematopoietic-B_cells-Memory_B|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DOCK8 DDHD1 NLRP1 IKZF1

8.32e-051775840d1c39e99144fdb9c7f6f98a1ade41c73db45b65
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_A_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SMARCA1 LAMA2 EGFLAM TOP2B

8.32e-051775841dc69c661e70e7e22bd9d7cf953eb638da9fd43c
ToppCell356C-Fibroblasts-Fibroblast-C_(Myofibroblast)|356C / Donor, Lineage, Cell class and subclass (all cells)

A2M COL8A1 MXRA5 LAMA2

8.32e-05177584db222faaecbe5600da39277243c4e7e764eb63c9
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_A_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SMARCA1 LAMA2 EGFLAM TOP2B

8.32e-05177584426a9845df7fd13b02e744532c336c60bc4d4a22
ToppCellFetal_29-31_weeks-Mesenchymal-vascular_smooth_muscle_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

RNF152 DGKG EGFLAM MYOM2

8.51e-05178584066dbc4cc2083c549d98122ed44707127f34d582
ToppCell3'-Adult-SmallIntestine-Hematopoietic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DOCK8 DDHD1 NLRP1 IKZF1

8.51e-05178584da1695a936dbe3ca9ee3fb28ceb60511c47b35f8
ToppCell3'-Adult-SmallIntestine-Hematopoietic-B_cells|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DOCK8 DDHD1 NLRP1 IKZF1

8.51e-05178584580fc1d45b82010c665a313b2e7a21e0116819ef
ToppCellT_cells-TFH-like_cells|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis

IGFBP4 IL6R MYB VDR

8.51e-05178584e2ae43e5ec31de6197f2cbd6089f944adbf0a163
ToppCell3'-GW_trimst-1.5-LargeIntestine-Hematopoietic|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DOCK8 IKZF1 IL6R CD300C

8.69e-05179584716856b2c7c660bf5ce00e63efeda6ed121f2baa
ToppCelldroplet-Lung-18m-Mesenchymal-myofibroblast-pericyte_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

COL8A1 SMARCA1 LAMA2 EGFLAM

8.69e-05179584f5bb4d3a27d56698473219970e764084096cc582
ToppCellCOVID-19-kidney-REN+Pericyte|kidney / Disease (COVID-19 only), tissue and cell type

A2M IGFBP4 LAMA2 DGKG

8.69e-05179584342c1cc4444f51b8dcb30d3adc98285a25669c6e
ToppCelldroplet-Lung-18m-Mesenchymal-myofibroblast-pericyte_cell-pericyte|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

COL8A1 SMARCA1 LAMA2 EGFLAM

8.69e-05179584fa03ec3cc0132f977b4cb28e7b23789732375183
ToppCelldroplet-Lung-nan-18m-Mesenchymal-Pericyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL8A1 SMARCA1 LAMA2 EGFLAM

8.88e-05180584f6a05b3751b01e74b2de8440801b0eb2e723c199
ToppCelldroplet-Lung-nan-18m-Mesenchymal-pericyte_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL8A1 SMARCA1 LAMA2 EGFLAM

8.88e-05180584dfc75ae4395ff46fbec2c54915d98ead5a1ba1a1
ToppCell11.5-Distal-Immune-Immune|Distal / Age, Tissue, Lineage and Cell class

DOCK8 IKZF1 IL6R CD300C

9.07e-05181584193ee02f547a218b2fc13e1174ea4cff4f8a3450
ToppCellControl-Myeloid|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DOCK8 NLRP1 IL6R CD300C

9.07e-0518158425170e5285996cc80337d5f86a0255569861ae77
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Epithelial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

A2M COL8A1 MIS18BP1 LAMA2

9.27e-05182584904804813849b7f7f716ba1554d33b07bc0a701e
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Epithelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

A2M COL8A1 MIS18BP1 LAMA2

9.27e-051825845d8b7fe18286e27f0f50c5d2d9be56850e2cb8f4
ToppCellwk_15-18-Hematologic-Myeloid-pre-pDC/DC5|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

DOCK8 IKZF1 IL6R CD300C

9.27e-05182584748401d2c84260a777001dd75b0182453185addc
ToppCellBronchial_Biopsy-Immune-T_and_NK|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X

LAMA2 IKZF1 EGFLAM CD300C

9.27e-05182584dab2ea0298e26649a923c34d4699e437e9385b90
ToppCell3'-GW_trimst-1.5-SmallIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

A2M MIS18BP1 IGFBP4 RASAL2

9.47e-0518358452af3c943116073c8ddd207b664342960b88929b
ToppCellLA-07._Pericyte|World / Chamber and Cluster_Paper

A2M RNF152 EGFLAM RASAL2

9.47e-05183584e3835db4795362b0442d5893baf2a78efcc20428
ToppCellRA-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

A2M RNF152 DGKG RASAL2

9.47e-05183584cae2ee08f985a6f005b4b8e959e465350315156a
ToppCell3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

A2M EXOC6 IGFBP4 SOCS3

9.67e-0518458416ed515fb673a9d6973133afcda0a3fba4a8d9dc
ToppCellPCW_10-12-Hematologic_Myeloid-Hem_Myeloid_dendritic-im_conventional_dendritic_(19)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

DOCK8 IKZF1 VDR CCSER1

9.67e-05184584315bb14e848d8e8e4533122047df6f9b89b89d99
ToppCellLV-15._Ventricular_Cardiomyocyte_III|LV / Chamber and Cluster_Paper

LAMA2 DGKG MYOM2 CCSER1

9.67e-05184584ab7a1620c14a9d9b6be1b47c559931e345e9eef8
ToppCellCOVID-19_Severe-gd_T|COVID-19_Severe / Disease condition and Cell class

A2M DIP2A LAMA2 MYOM2

9.67e-05184584791f1bcb954aadc63d4117c400537d036f68734d
ToppCellCV-Moderate-7|Moderate / Virus stimulation, Condition and Cluster

A2M KMT2D DOCK8 DDHD1

9.87e-05185584a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
ToppCellCOVID-19-Fibroblasts-Pericytes|COVID-19 / group, cell type (main and fine annotations)

RNF152 DGKG EGFLAM RASAL2

9.87e-051855844905adaeeffd353e089578e5ea614437dbe794e6
ToppCellLA-07._Pericyte|LA / Chamber and Cluster_Paper

A2M RNF152 EGFLAM RASAL2

9.87e-05185584ba5baa4d7f097108622674de5b7f4fd279843d24
ToppCellControl-T_cells-CD8+_T_cells|Control / group, cell type (main and fine annotations)

A2M DIP2A DOCK8 IKZF1

9.87e-0518558402ab64c0166c0646d1d4c6ed110ef0b75a1096d0
ToppCell(1)_Control_(PBS)-(2)_LEPR+_perivascular_cells_and_VE-Cad+_vascular_cells_(mixed)|World / Stress and Cell class

IGFBP4 RBMS1 SOCS3 VDR

9.87e-05185584b8cd94cf18308b514fc61557550225794ffd2860
ToppCellwk_08-11-Hematologic-Myeloid-Cycling_DC|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

CD1E DOCK8 IKZF1 IL6R

1.01e-04186584de1f0bc5dbf6dc0e716f5ebbf2bbcfe249811c54
DrugLithocholic acid [434-13-9]; Up 200; 10.6uM; MCF7; HT_HG-U133A

CD1E NLRP1 IKZF1 MED1 RASAL2 CD300C

8.07e-061945664373_UP
Drug2-Chloropyrazine [14508-49-7]; Up 200; 35uM; PC3; HT_HG-U133A

A2M LAMA2 NLRP1 IKZF1 RASAL2 CD300C

8.81e-061975665750_UP
DrugThiamine hydrochloride [67-03-8]; Up 200; 11.8uM; MCF7; HT_HG-U133A

A2M ZNF750 CD1E SOCS3 IKZF1 RASAL2

9.60e-062005662894_UP
Drugtris(2,3-dichloropropyl) phosphate

IGFBP4 NLRP1 MYB

1.56e-0520563CID000006538
DrugN-acetylcysteamine

ACACA SOCS3 NLRP1

1.82e-0521563CID000014484
Drugdimercaptosuccinic acid

MBTPS2 NLRP1 VDR

2.41e-0523563CID000009354
DrugK00051

A2M IL6R TOP2B MYB

2.82e-0571564CID009549278
Drugungeremine

TOP2B MYB

3.55e-054562CID000159646
Drug1,25(OH)2-16-ene-23-yne-26,27-hexafluoro-19-nor-D3

MED1 VDR

3.55e-054562ctd:C408047
Drugfredericamycin A

ACACA TOP2B

5.91e-055562CID005384075
DrugWR-1065

NLRP1 TOP2B MYB

7.99e-0534563CID000104807
Drug26,26,26,27,27,27-hexafluoro-1,25-dihydroxyvitamin D3

MED1 VDR

8.86e-056562ctd:C040488
Drugaminoanthraquinone

BNC1 TOP2B

8.86e-056562CID000008341
DrugSCMC

ACO1 NLRP1 CDON

9.50e-0536563CID000001080
DrugDiphenhydramine hydrochloride [147-24-0]; Down 200; 13.8uM; MCF7; HT_HG-U133A

MIS18BP1 PHF3 MED1 HAUS2 VDR

1.06e-041915656020_DN
DrugMuramic acid, N-acetyl [10597-89-4]; Up 200; 13.6uM; MCF7; HT_HG-U133A

ARHGAP4 PHF3 IKZF1 RASAL2 PRRC2B

1.12e-041935653262_UP
DrugBenfluorex hydrochloride [23642-66-2]; Up 200; 10.4uM; MCF7; HT_HG-U133A

CD1E SMARCA1 MED1 CD300C VDR

1.15e-041945652621_UP
DrugRapamycin; Up 200; 0.1uM; HL60; HT_HG-U133A

PHF3 SMARCA1 DGKG NLRP1 CD300C

1.17e-041955652702_UP
DrugEpiandrosterone [481-29-8]; Down 200; 13.8uM; HL60; HT_HG-U133A

MBTPS2 ACO1 DGKG IL6R CD300C

1.17e-041955652444_DN
DrugSC 19220; Up 200; 10uM; MCF7; HT_HG-U133A

HAUS5 DGKG HAUS2 RASAL2 VDR

1.17e-041955657060_UP
DrugTrichlorfon [52-68-6]; Up 200; 15.6uM; MCF7; HT_HG-U133A

KMT2D LAMA2 DGKG RASAL2 CD300C

1.20e-041965655989_UP
DrugBenzathine benzylpenicillin [5928-84-7]; Up 200; 4.2uM; HL60; HT_HG-U133A

A2M CD1E LAMA2 NLRP1 RASAL2

1.20e-041965652939_UP
DrugAcetaminophen [103-90-2]; Down 200; 26.4uM; HL60; HT_HG-U133A

RALGAPA1 NLRP1 IKZF1 CD300C POLR3F

1.20e-041965653025_DN
Drug2-methylcitric acid

ACACA ACO1 CDON

1.21e-0439563CID000000515
DrugDiloxanide furoate [3736-81-0]; Down 200; 12.2uM; MCF7; HT_HG-U133A

A2M IKZF1 IL6R CDON MYB

1.23e-041975653399_DN
DrugLiothyronine [6893-02-3]; Down 200; 6.2uM; HL60; HT_HG-U133A

MBTPS2 NLRP1 IKZF1 CDON MYB

1.23e-041975652984_DN
DrugIndoprofen [31842-01-0]; Up 200; 14.2uM; PC3; HT_HG-U133A

PHF3 SOCS3 LAMA2 NLRP1 IKZF1

1.23e-041975654249_UP
DrugClonidine hydrochloride [4205-91-8]; Up 200; 15uM; PC3; HT_HG-U133A

COL8A1 PHF3 IKZF1 CACNA1G CDON

1.23e-041975654478_UP
DrugEthynylestradiol 3-methyl ether [72-33-3]; Up 200; 12.8uM; HL60; HT_HG-U133A

RALGAPA1 CD1E DGKG NLRP1 CD300C

1.23e-041975653008_UP
DrugFamotidine [76824-35-6]; Up 200; 11.8uM; MCF7; HT_HG-U133A

A2M COL8A1 SMARCA1 MED1 CDON

1.26e-041985651529_UP
DrugIodixanol [92339-11-2]; Up 200; 2.6uM; HL60; HT_HG-U133A

RALGAPA1 KMT2D TNPO2 CACNA1G VDR

1.26e-041985653023_UP
DrugSulfamerazine [127-79-7]; Up 200; 15.2uM; MCF7; HT_HG-U133A

ARHGAP4 ZNF750 SOCS3 LAMA2 CDON

1.26e-041985656036_UP
DrugPropidium iodide [25535-16-4]; Down 200; 6uM; HL60; HT_HG-U133A

IGFBP4 MBTPS2 IKZF1 CDON VDR

1.26e-041985652541_DN
DrugNiacin [59-67-6]; Down 200; 32.4uM; MCF7; HT_HG-U133A

MED1 IL6R RASAL2 MYB VDR

1.29e-041995653381_DN
DrugPhenylpropanolamine hydrochloride [154-41-6]; Up 200; 21.4uM; PC3; HT_HG-U133A

COL8A1 KMT2D HAUS5 LAMA2 IKZF1

1.29e-041995656699_UP
Drugestradiol, USP; Down 200; 0.1uM; MCF7; HG-U133A

BNC1 HAUS5 LUZP2 IKZF1 IL6R

1.29e-04199565365_DN
DrugCoralyne chloride hydrate [38989-38-7]; Up 200; 9.6uM; PC3; HT_HG-U133A

RALGAPA1 MBTPS2 HAUS5 IKZF1 CACNA1G

1.29e-041995656317_UP
DrugCarbenoxolone disodium salt [7421-40-1]; Up 200; 6.6uM; MCF7; HT_HG-U133A

CD1E TNPO2 SOCS3 LAMA2 MED1

1.29e-041995653353_UP
DrugBenzonatate [104-31-4]; Up 200; 6.6uM; MCF7; HT_HG-U133A

COL8A1 MBTPS2 MED1 RASAL2 CDON

1.29e-041995651679_UP
DrugDisopyramide [3737-09-5]; Up 200; 11.8uM; HL60; HT_HG-U133A

COL8A1 DGKG IKZF1 CD300C VDR

1.29e-041995652408_UP
DrugPHA-00846566E [724718-26-7]; Down 200; 10uM; PC3; HT_HG-U133A

PDPK1 HAUS5 NLRP1 POLR3F VDR

1.32e-042005657046_DN
Drugtris

NAT2 TRIT1 ACO1 MED1 VDR

1.62e-04209565CID000006503
DrugAC1L3UEY

SMARCA1 MED1 MYB VDR

1.73e-04113564CID000122342
DrugCS-0398

IGFBP4 TOP2B VDR

1.74e-0444563CID005288149
Diseaseatopic dermatitis (is_implicated_in)

NAT2 DOCK8 VDR

1.81e-0526583DOID:3310 (is_implicated_in)
DiseaseDiffuse Large B-Cell Lymphoma

KMT2D PDPK1 IKZF1

1.76e-0455583C0079744
Diseaseprecuneus cortex volume measurement

COL8A1 CCSER1

3.40e-0414582EFO_0010326
Diseasemyopia (is_implicated_in)

LAMA2 VDR

4.48e-0416582DOID:11830 (is_implicated_in)
DiseaseParkinson's disease (is_implicated_in)

A2M NAT2 VDR

4.58e-0476583DOID:14330 (is_implicated_in)
DiseaseLiver carcinoma

A2M NAT2 ACACA MBTPS2 SOCS3 MED1

4.75e-04507586C2239176
Diseasehip circumference

RALGAPA1 MXRA5 DOCK8 DGKG CCSER1

5.34e-04338585EFO_0005093
DiseasePseudopelade

MBTPS2 VDR

6.36e-0419582C0086873
Diseasevitiligo (is_implicated_in)

NLRP1 VDR

7.78e-0421582DOID:12306 (is_implicated_in)
Diseaseneutrophil percentage of leukocytes

MED24 EXOC6 DOCK8 RBMS1 IKZF1 MYB

1.24e-03610586EFO_0007990
Diseaseprostate cancer (is_implicated_in)

NAT2 PDPK1 VDR

1.60e-03117583DOID:10283 (is_implicated_in)

Protein segments in the cluster

PeptideGeneStartEntry
HPPPGSHLLYAKMIQ

VDR

371

P11473
QVIGYRLMGKPHPLV

ACO1

241

P21399
KMPRHPGSPILGYTV

EGFLAM

56

Q63HQ2
HALSKLRIPPMYPTS

BNC1

66

Q01954
GPLHGMLINTPYVTK

ACACA

1566

Q13085
PPRGPISLHMYSRKN

CCSER1

866

Q9C0I3
QMPILYGHPATLLKD

LINC02877

51

P0CE67
SGKPQYMVLVPSLLH

A2M

26

P01023
LLLVPGYFPLSHPMT

CD300C

16

Q08708
PYILQHPGAVLTPSM

RBMS1

311

P29558
IQGHKPTATPIKMPY

TRIT1

371

Q9H3H1
LYKHDIIMPPLPFTS

HAUS2

211

Q9NVX0
MIATPLKHSRIYLPP

MIS18BP1

1

Q6P0N0
KYGHITPMAQRKLPP

PERCC1

201

A0A1W2PR82
KMGILQEHPIPLSYS

NLRP1

606

Q9C000
LKMLNTNYHLPPSPK

MT-ATP8

26

P03928
YHLNNPIPAMPKASI

RASAL2

786

Q9UJF2
INLTGPLPAPYKMLY

LAMA2

1596

P24043
YGPLKMLPQTPSHLV

MYB

481

P10242
GKIIQKTPYPHPRGM

PMS2P1

341

A4D2B8
KTPYPHPRGMTVSVK

PMS2P1

346

A4D2B8
LLHMKTSLPPGLPTQ

HAUS5

536

O94927
VPVISPMYQLHKPLA

IKZF1

341

Q13422
PMYQLHKPLAEGTPR

IKZF1

346

Q13422
PKKFPMSQSVPHIYI

EXOC6

476

Q8TAG9
VMQYKIIPTPGTHPL

DGKG

421

P49619
KNILSPHTPSPVFLM

CD1E

336

P15812
KTSMHPPYSLGQLVP

IL6R

401

P08887
GFPLHMPYSEVKPLI

CC2D2A

1561

Q9P2K1
LPVALEKLPPNYSMH

DOCK8

686

Q8NF50
SLNIPPGPYSSMHKL

CACNA1G

621

O43497
PKPEMLLGLAALHIY

FRMPD3

301

Q5JV73
PLLKPLHTIVGYGRM

GALNT8

486

Q9NY28
PYPQDGLEMKPLSHV

CDON

1141

Q4KMG0
HTPPVQKGLRYGMIL

MT-CO3

71

P00414
YQPLGQQVPHMPLAK

COL8A1

51

P27658
MKFSPAHYLLPLLPA

LUZP2

1

Q86TE4
KHPPQIDMLYVGHPL

MBTPS2

401

O43462
PPVNKYSTGMVHLLL

NAT2

96

P11245
NPLPYEHMKPSFLNP

DDHD1

691

Q8NEL9
PPPRKAVLSMNGLSY

DIP2A

686

Q14689
PGTPIPAEIHYTLLM

SACS

4156

Q9NZJ4
YKLPIAPLIMGSHPV

MED1

266

Q15648
LYHTPPGSPQLAMLK

PLEKHA8P1

66

O95397
FIKLPSNGCYMLPLP

RNF152

91

Q8N8N0
KHYRNIPGPHMVLVP

SMARCA1

226

P28370
PHPMLPNYKNFKGTI

TOP2B

906

Q02880
HQQTPPKLTAYLPAM

PDPK1

351

O15530
KELHVHPPGMQYPDL

SLITRK3

911

O94933
MIGPSPNPLILSYLK

MED24

51

O75448
HMKLYRAVNPIIPPT

POLR3F

266

Q9H1D9
YPPRGVEKPLHTLMH

IGFBP4

81

P22692
MRGLIPHKYITLPAG

ARHGAP4

791

P98171
KGLGAISPYMHPTIP

ZNF750

226

Q32MQ0
SLYHPILDIPQMRPK

RALGAPA1

261

Q6GYQ0
MQGMVPYLPELIPHL

TNPO2

426

O14787
MYLIPLGATDKIPHP

PHF3

1311

Q92576
GYPLPHPKSSDTLAM

PRRC2B

756

Q5JSZ5
LKLVHHYMPPPGAPS

SOCS3

121

O14543
MPAKPLQHFSSPGAL

KMT2D

4001

O14686
SHVYMLPNGTLSIPK

MXRA5

626

Q9NR99
LPIGLPLSSMIPYTH

MYOM2

261

P54296