Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiondelayed rectifier potassium channel activity

KCNG2 KCNA2 KCNB1 KCNS3

6.65e-0628884GO:0005251
GeneOntologyMolecularFunction2-oxoglutarate-dependent dioxygenase activity

PHF2 KDM5B ALKBH2 P3H2 OGFOD1

9.94e-0665885GO:0016706
GeneOntologyMolecularFunctionmicrofilament motor activity

MYH2 MYH3 MYH7 MYO9A

2.32e-0538884GO:0000146
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen

MOXD2P PHF2 KDM5B ALKBH2 P3H2 CYP24A1 OGFOD1

2.40e-05194887GO:0016705
GeneOntologyMolecularFunctiondioxygenase activity

PHF2 KDM5B ALKBH2 P3H2 OGFOD1

7.29e-0598885GO:0051213
GeneOntologyMolecularFunctioniron ion binding

PHF2 ALKBH2 P3H2 CYP24A1 OGFOD1 LTF

9.31e-05166886GO:0005506
GeneOntologyMolecularFunctionpeptidyl-proline 3-dioxygenase activity

P3H2 OGFOD1

1.15e-044882GO:0031544
GeneOntologyMolecularFunctioncytoskeletal motor activity

MYH2 MYH3 MYH7 MYO9A DNAH1

1.75e-04118885GO:0003774
GeneOntologyMolecularFunctionmetalloendopeptidase activity

ADAMTS3 TLL1 ADAMTS20 ADAMTS13 ADAM32

1.90e-04120885GO:0004222
GeneOntologyMolecularFunctioncytoskeletal protein binding

NPHS1 MYH2 MYH3 MYH7 KCNA2 DST FMR1 ALMS1 ANK3 BRCA2 XIRP2 MYO9A VPS41 RP1

3.05e-0410998814GO:0008092
GeneOntologyMolecularFunctionalpha-actinin binding

NPHS1 ALMS1 XIRP2

3.40e-0431883GO:0051393
GeneOntologyMolecularFunctionstructural constituent of presynaptic active zone

BSN RIMS2

5.28e-048882GO:0098882
GeneOntologyMolecularFunctiontransition metal ion binding

MOXD2P PHF2 KDM5B ADAMTS3 ALKBH2 P3H2 TLL1 CYP24A1 SF3A3 ADAMTS20 OGFOD1 ALB ADAMTS13 LTF

6.70e-0411898814GO:0046914
GeneOntologyMolecularFunctionpotassium ion transmembrane transporter activity

KCNG2 KCNA2 SLC12A4 KCNB1 KCNS3

8.63e-04167885GO:0015079
GeneOntologyMolecularFunctionactinin binding

NPHS1 ALMS1 XIRP2

8.99e-0443883GO:0042805
GeneOntologyMolecularFunctiondemethylase activity

PHF2 KDM5B ALKBH2

9.61e-0444883GO:0032451
GeneOntologyMolecularFunctionvoltage-gated potassium channel activity

KCNG2 KCNA2 KCNB1 KCNS3

1.08e-03102884GO:0005249
GeneOntologyMolecularFunctionglycosaminoglycan binding

NELL2 ADAMTS3 SUSD5 LTBP2 LTF NRP2

1.19e-03268886GO:0005539
GeneOntologyMolecularFunctionpeptidyl-proline dioxygenase activity

P3H2 OGFOD1

1.23e-0312882GO:0031543
GeneOntologyMolecularFunctionheparin binding

NELL2 ADAMTS3 LTBP2 LTF NRP2

1.60e-03192885GO:0008201
GeneOntologyMolecularFunctionmetallopeptidase activity

ADAMTS3 TLL1 ADAMTS20 ADAMTS13 ADAM32

1.92e-03200885GO:0008237
GeneOntologyMolecularFunctionpotassium channel activity

KCNG2 KCNA2 KCNB1 KCNS3

2.48e-03128884GO:0005267
GeneOntologyMolecularFunctionactin filament binding

MYH2 MYH3 MYH7 XIRP2 MYO9A

3.31e-03227885GO:0051015
GeneOntologyMolecularFunctiontranscription coregulator activity

PHF2 YEATS2 KDM5B KMT2D LIMD1 NFKBIB SIN3A TFAP2A

3.35e-03562888GO:0003712
GeneOntologyMolecularFunctiontranscription corepressor activity

YEATS2 KDM5B LIMD1 SIN3A TFAP2A

3.44e-03229885GO:0003714
GeneOntologyMolecularFunctionL-ascorbic acid binding

P3H2 OGFOD1

3.46e-0320882GO:0031418
GeneOntologyMolecularFunctionvoltage-gated monoatomic cation channel activity

KCNG2 KCNA2 KCNB1 KCNS3

4.59e-03152884GO:0022843
GeneOntologyMolecularFunctionprotein-macromolecule adaptor activity

PHF2 YEATS2 KDM5B KMT2D FMR1 ANK3 LIMD1 NFKBIB OBSL1 SIN3A RIMS2 TFAP2A

4.81e-0311608812GO:0030674
GeneOntologyBiologicalProcesspeptidyl-proline hydroxylation

ERO1B P3H2 OGFOD1

2.55e-0514873GO:0019511
GeneOntologyBiologicalProcessmuscle filament sliding

MYH2 MYH3 MYH7

3.18e-0515873GO:0030049
GeneOntologyBiologicalProcessactin-myosin filament sliding

MYH2 MYH3 MYH7

5.65e-0518873GO:0033275
GeneOntologyBiologicalProcessanatomical structure arrangement

KCNA2 TFAP2A NRP2

9.12e-0521873GO:0048532
GeneOntologyCellularComponentmuscle myosin complex

MYH2 MYH3 MYH7

3.88e-0516883GO:0005859
GeneOntologyCellularComponentsarcomere

MYH2 MYH3 MYH7 DST ANK3 XIRP2 OBSL1

8.74e-05249887GO:0030017
GeneOntologyCellularComponentextracellular matrix

NPHS1 FBLN2 DST ADAMTS3 MUC17 P3H2 ADAMTS20 LTBP2 ALB ADAMTS13 LRRTM1

9.55e-056568811GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

NPHS1 FBLN2 DST ADAMTS3 MUC17 P3H2 ADAMTS20 LTBP2 ALB ADAMTS13 LRRTM1

9.81e-056588811GO:0030312
GeneOntologyCellularComponentmyosin complex

MYH2 MYH3 MYH7 MYO9A

1.12e-0459884GO:0016459
GeneOntologyCellularComponentmyofibril

MYH2 MYH3 MYH7 DST ANK3 XIRP2 OBSL1

1.55e-04273887GO:0030016
GeneOntologyCellularComponentmyosin filament

MYH2 MYH3 MYH7

1.55e-0425883GO:0032982
GeneOntologyCellularComponentsynaptic membrane

GABRG2 KCNA2 FMR1 ANK3 KCNB1 LRRTM1 BSN RIMS2 GPR179 NRP2

1.69e-045838810GO:0097060
GeneOntologyCellularComponentmyosin II complex

MYH2 MYH3 MYH7

2.19e-0428883GO:0016460
GeneOntologyCellularComponentcontractile muscle fiber

MYH2 MYH3 MYH7 DST ANK3 XIRP2 OBSL1

2.24e-04290887GO:0043292
GeneOntologyCellularComponentinhibitory synapse

GABRG2 BSN RIMS2

2.98e-0431883GO:0060077
GeneOntologyCellularComponentpostsynaptic membrane

GABRG2 KCNA2 FMR1 ANK3 KCNB1 LRRTM1 GPR179 NRP2

3.08e-04405888GO:0045211
GeneOntologyCellularComponentcollagen-containing extracellular matrix

NPHS1 FBLN2 DST ADAMTS3 MUC17 P3H2 ADAMTS20 LTBP2 ALB

3.91e-04530889GO:0062023
GeneOntologyCellularComponentZ disc

MYH7 DST ANK3 XIRP2 OBSL1

4.45e-04151885GO:0030018
GeneOntologyCellularComponentcytoskeleton of presynaptic active zone

BSN RIMS2

4.83e-048882GO:0048788
GeneOntologyCellularComponentvoltage-gated potassium channel complex

KCNG2 KCNA2 KCNB1 KCNS3

5.93e-0491884GO:0008076
GeneOntologyCellularComponentI band

MYH7 DST ANK3 XIRP2 OBSL1

6.85e-04166885GO:0031674
GeneOntologyCellularComponentcytoplasmic region

DST FMR1 RP1 CFAP43 BSN RIMS2 DNAH1

8.14e-04360887GO:0099568
GeneOntologyCellularComponentpotassium channel complex

KCNG2 KCNA2 KCNB1 KCNS3

9.78e-04104884GO:0034705
GeneOntologyCellularComponentpostsynapse

GABRG2 KCNA2 DST FMR1 FRMPD4 ANK3 KCNB1 MYO9A LRRTM1 BSN GPR179 NRP2

1.13e-0310188812GO:0098794
GeneOntologyCellularComponentpostsynaptic specialization

GABRG2 DST FMR1 FRMPD4 ANK3 KCNB1 LRRTM1 BSN

1.27e-03503888GO:0099572
GeneOntologyCellularComponentA band

MYH2 DST OBSL1

1.37e-0352883GO:0031672
GeneOntologyCellularComponentpresynaptic cytoskeleton

BSN RIMS2

1.54e-0314882GO:0099569
GeneOntologyCellularComponentbasement membrane

NPHS1 DST P3H2 ALB

1.76e-03122884GO:0005604
GeneOntologyCellularComponentproximal dendrite

FMR1 KCNB1

1.78e-0315882GO:1990635
GeneOntologyCellularComponentplasma membrane bounded cell projection cytoplasm

DST FMR1 RP1 CFAP43 BSN DNAH1

2.22e-03317886GO:0032838
GeneOntologyCellularComponentintercalated disc

DST ANK3 OBSL1

2.97e-0368883GO:0014704
GeneOntologyCellularComponentpresynaptic active zone cytoplasmic component

BSN RIMS2

4.19e-0323882GO:0098831
GeneOntologyCellularComponentaxon

GABRG2 KCNA2 DST FMR1 ANK3 KCNB1 MYO9A LRRTM1 BSN NRP2

4.20e-038918810GO:0030424
MousePhenomuscle spasm

GABRG2 DST GAN BSN NRP2

1.92e-0560775MP:0000743
MousePhenomuscle twitch

GABRG2 DST GAN BSN NRP2

2.63e-0564775MP:0009046
MousePhenoseizures

GABRG2 KCNA2 DST FMR1 ANK3 MYO9A EIF2B5 GAN BSN NRP2

2.68e-053607710MP:0002064
DomainK_chnl_volt-dep_Kv

KCNG2 KCNA2 KCNB1 KCNS3

6.78e-0627864IPR003968
DomainVG_K_chnl

KCNG2 KCNA2 KCNB1 KCNS3

1.55e-0533864IPR028325
DomainMyosin_head_motor_dom

MYH2 MYH3 MYH7 MYO9A

2.74e-0538864IPR001609
DomainMYOSIN_MOTOR

MYH2 MYH3 MYH7 MYO9A

2.74e-0538864PS51456
DomainMyosin_head

MYH2 MYH3 MYH7 MYO9A

2.74e-0538864PF00063
DomainMYSc

MYH2 MYH3 MYH7 MYO9A

2.74e-0538864SM00242
DomainDISINTEGRIN_1

ADAMTS3 ADAMTS20 ADAMTS13 ADAM32

3.37e-0540864PS00427
DomainReprolysin

ADAMTS3 ADAMTS20 ADAMTS13 ADAM32

3.37e-0540864PF01421
DomainADAM_MEPRO

ADAMTS3 ADAMTS20 ADAMTS13 ADAM32

3.37e-0540864PS50215
DomainDISINTEGRIN_2

ADAMTS3 ADAMTS20 ADAMTS13 ADAM32

3.37e-0540864PS50214
DomainPeptidase_M12B

ADAMTS3 ADAMTS20 ADAMTS13 ADAM32

3.37e-0540864IPR001590
DomainMetalloPept_cat_dom

ADAMTS3 TLL1 ADAMTS20 ADAMTS13 ADAM32

3.58e-0581865IPR024079
Domain-

ADAMTS3 TLL1 ADAMTS20 ADAMTS13 ADAM32

3.58e-05818653.40.390.10
DomainDisintegrin_dom

ADAMTS3 ADAMTS20 ADAMTS13 ADAM32

3.73e-0541864IPR001762
DomainMyosin_N

MYH2 MYH3 MYH7

4.12e-0515863PF02736
DomainMyosin_N

MYH2 MYH3 MYH7

4.12e-0515863IPR004009
DomainMyosin_tail_1

MYH2 MYH3 MYH7

7.32e-0518863PF01576
DomainMyosin_tail

MYH2 MYH3 MYH7

7.32e-0518863IPR002928
DomainMyosin-like_IQ_dom

MYH2 MYH3 MYH7

8.66e-0519863IPR027401
Domain-

MYH2 MYH3 MYH7

8.66e-05198634.10.270.10
DomainBTB_2

KCNG2 KCNA2 KCNB1 KCNS3

1.03e-0453864PF02214
DomainT1-type_BTB

KCNG2 KCNA2 KCNB1 KCNS3

1.03e-0453864IPR003131
DomainEGF

NELL2 FBLN2 MUC17 TLL1 LTBP2 ADAM32 GPR179

1.05e-04235867SM00181
DomainFE2OG_OXY

ALKBH2 P3H2 OGFOD1

1.18e-0421863PS51471
DomainChannel_four-helix_dom

KCNG2 KCNA2 KCNB1 KCNS3

1.37e-0457864IPR027359
Domain-

KCNG2 KCNA2 KCNB1 KCNS3

1.37e-04578641.20.120.350
DomainOxoglu/Fe-dep_dioxygenase

ALKBH2 P3H2 OGFOD1

1.56e-0423863IPR005123
DomainPeptidase_M12B_ADAM-TS

ADAMTS3 ADAMTS20 ADAMTS13

1.78e-0424863IPR013273
DomainBTB

KCNG2 GMCL2 KCNA2 KCNB1 GAN KCNS3

1.83e-04180866SM00225
DomainBTB/POZ_dom

KCNG2 GMCL2 KCNA2 KCNB1 GAN KCNS3

2.12e-04185866IPR000210
DomainIQ

MYH2 MYH3 MYH7 MYO9A

5.32e-0481864SM00015
DomainZnf_FYVE_PHD

PHF2 KDM5B KMT2D BSN RIMS2

5.89e-04147865IPR011011
DomainEGF_CA

NELL2 FBLN2 TLL1 LTBP2

6.68e-0486864PF07645
DomainEGF_3

NELL2 FBLN2 MUC17 TLL1 LTBP2 ADAM32

7.56e-04235866PS50026
DomainPeptidase_M12B_N

ADAMTS3 ADAMTS20 ADAM32

7.64e-0439863IPR002870
DomainPep_M12B_propep

ADAMTS3 ADAMTS20 ADAM32

7.64e-0439863PF01562
DomainIQ_motif_EF-hand-BS

MYH2 MYH3 MYH7 MYO9A

7.92e-0490864IPR000048
DomainIQ

MYH2 MYH3 MYH7 MYO9A

8.96e-0493864PS50096
DomainEGF-like_dom

NELL2 FBLN2 MUC17 TLL1 LTBP2 ADAM32

1.02e-03249866IPR000742
DomainEGF_Ca-bd_CS

NELL2 FBLN2 TLL1 LTBP2

1.05e-0397864IPR018097
Domain-

PHF2 KDM5B RNF113B KMT2D VPS41 BSN TTC3 RIMS2

1.08e-034498683.30.40.10
DomainZINC_PROTEASE

ADAMTS3 TLL1 ADAMTS20 ADAMTS13

1.09e-0398864PS00142
DomainEGF_CA

NELL2 FBLN2 TLL1 LTBP2

1.13e-0399864PS01187
DomainEGF_1

NELL2 FBLN2 MUC17 TLL1 LTBP2 ADAM32

1.15e-03255866PS00022
DomainZnf_RING/FYVE/PHD

PHF2 KDM5B RNF113B KMT2D VPS41 BSN TTC3 RIMS2

1.24e-03459868IPR013083
DomainEGF-like_CS

NELL2 FBLN2 MUC17 TLL1 LTBP2 ADAM32

1.30e-03261866IPR013032
DomainEGF_2

NELL2 FBLN2 MUC17 TLL1 LTBP2 ADAM32

1.40e-03265866PS01186
DomainEGF-type_Asp/Asn_hydroxyl_site

NELL2 FBLN2 TLL1 LTBP2

1.46e-03106864IPR000152
DomainSKP1/BTB/POZ

KCNG2 KCNA2 KCNB1 GAN KCNS3

1.81e-03189865IPR011333
DomainCUB

TLL1 ADAMTS13 NRP2

1.87e-0353863PS01180
DomainIon_trans_dom

KCNG2 KCNA2 KCNB1 KCNS3

1.90e-03114864IPR005821
DomainIon_trans

KCNG2 KCNA2 KCNB1 KCNS3

1.90e-03114864PF00520
DomainCUB_dom

TLL1 ADAMTS13 NRP2

2.31e-0357863IPR000859
DomainP4Hc

P3H2 OGFOD1

2.41e-0316862SM00702
DomainPro_4_hyd_alph

P3H2 OGFOD1

2.41e-0316862IPR006620
DomainEGF_CA

NELL2 FBLN2 TLL1 LTBP2

2.44e-03122864SM00179
DomainEGF-like_Ca-bd_dom

NELL2 FBLN2 TLL1 LTBP2

2.58e-03124864IPR001881
DomainEGF_extracell

NELL2 LTBP2 ADAM32

2.67e-0360863IPR013111
DomainEGF_2

NELL2 LTBP2 ADAM32

2.67e-0360863PF07974
Domain-

P3H2 VPS41 CABIN1 TTC3 CDC23

2.68e-032078651.25.40.10
DomainTSP_1

ADAMTS3 ADAMTS20 ADAMTS13

3.07e-0363863PF00090
DomainTSP1

ADAMTS3 ADAMTS20 ADAMTS13

3.35e-0365863SM00209
DomainTSP1_rpt

ADAMTS3 ADAMTS20 ADAMTS13

3.35e-0365863IPR000884
DomainTSP1

ADAMTS3 ADAMTS20 ADAMTS13

3.35e-0365863PS50092
Domain2OG-FeII_Oxy

ALKBH2 P3H2

3.41e-0319862PF03171
DomainIQ

MYH2 MYH3 MYO9A

4.30e-0371863PF00612
DomainTPR-like_helical_dom

P3H2 VPS41 CABIN1 TTC3 CDC23

4.44e-03233865IPR011990
PathwayREACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS

KCNG2 KCNA2 KCNB1 KCNS3

5.49e-0541724MM14546
PathwayREACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS

KCNG2 KCNA2 KCNB1 KCNS3

6.64e-0543724M1056
PathwayREACTOME_TFAP2A_ACTS_AS_A_TRANSCRIPTIONAL_REPRESSOR_DURING_RETINOIC_ACID_INDUCED_CELL_DIFFERENTIATION

TFAP2A MYBL2

2.55e-045722M27770
PathwayREACTOME_TFAP2_AP_2_FAMILY_REGULATES_TRANSCRIPTION_OF_CELL_CYCLE_FACTORS

KDM5B TFAP2A

2.55e-045722M27767
Pubmed

Kv7/KCNQ potassium channels in cortical hyperexcitability and juvenile seizure-related death in Ank2-mutant mice.

GABRG2 KCNA2 ANK3 KCNB1

1.14e-071888437321992
Pubmed

Distinct myogenic programs of embryonic and fetal mouse muscle cells: expression of the perinatal myosin heavy chain isoform in vitro.

MYH2 MYH3 MYH7

3.11e-0768831728586
Pubmed

Spatial and temporal changes in myosin heavy chain gene expression in skeletal muscle development.

MYH2 MYH3 MYH7

3.11e-07688310588881
Pubmed

A fast Myosin super enhancer dictates muscle fiber phenotype through competitive interactions with Myosin genes.

MYH2 MYH3 MYH7

5.44e-07788335210422
Pubmed

ANKK1 is found in myogenic precursors and muscle fibers subtypes with glycolytic metabolism.

MYH2 MYH3 MYH7

5.44e-07788329758057
Pubmed

Diversity in transcriptional start site selection and alternative splicing affects the 5'-UTR of mouse striated muscle myosin transcripts.

MYH2 MYH3 MYH7

5.44e-07788316819597
Pubmed

Calcineurin is necessary for the maintenance but not embryonic development of slow muscle fibers.

MYH2 MYH3 MYH7

2.55e-061188316024798
Pubmed

International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels.

KCNG2 KCNA2 KCNB1 KCNS3

3.26e-064088416382104
Pubmed

Contractile protein gene expression in primary myotubes of embryonic mouse hindlimb muscles.

MYH2 MYH3 MYH7

4.40e-06138838404542
Pubmed

Defective excitation-contraction coupling is partially responsible for impaired contractility in hindlimb muscles of Stac3 knockout mice.

MYH2 MYH3 MYH7

5.58e-061488327184118
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

KCNA2 DST FMR1 ANK3 KCNB1 MIOS LRRTM1 BSN CABIN1 TTC3 UNC79 NEURL4

5.64e-06963881228671696
Pubmed

Fluorescence measurements reveal stoichiometry of K+ channels formed by modulatory and delayed rectifier alpha-subunits.

KCNB1 KCNS3

6.33e-06288215827117
Pubmed

Overexpression of Jumonji AT-rich interactive domain 1B and PHD finger protein 2 is involved in the progression of esophageal squamous cell carcinoma.

PHF2 KDM5B

6.33e-06288222534467
Pubmed

Effects of bone fracture and surgery on plasma myosin heavy chain fragments of skeletal muscle.

MYH2 MYH7

6.33e-06288210579056
Pubmed

Analysis of albumin-associated peptides and proteins from ovarian cancer patients.

BRCA2 ALB

6.33e-06288216099937
Pubmed

AP-2alpha selectively regulates fragile X mental retardation-1 gene transcription during embryonic development.

FMR1 TFAP2A

6.33e-06288215930016
Pubmed

Novel BRCA2-Interacting Protein, LIMD1, Is Essential for the Centrosome Localization of BRCA2 in Esophageal Cancer Cell.

LIMD1 BRCA2

6.33e-06288227656835
Pubmed

Kv2.1/Kv9.3, a novel ATP-dependent delayed-rectifier K+ channel in oxygen-sensitive pulmonary artery myocytes.

KCNB1 KCNS3

6.33e-0628829362476
Pubmed

Structural and functional characterization of Kv6.2 a new gamma-subunit of voltage-gated potassium channel.

KCNG2 KCNB1

6.33e-06288210551266
Pubmed

Six homeoproteins and a Iinc-RNA at the fast MYH locus lock fast myofiber terminal phenotype.

MYH2 MYH3 MYH7

6.97e-061588324852826
Pubmed

IKKα and alternative NF-κB regulate PGC-1β to promote oxidative muscle metabolism.

MYH2 MYH7 NFKBIB

1.04e-051788322351927
Pubmed

Slow and fast fiber isoform gene expression is systematically altered in skeletal muscle of the Sox6 mutant, p100H.

MYH2 MYH3 MYH7

1.04e-051788316124007
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

YEATS2 KMT2D ALMS1 ANK3 LIMD1 SIN3A TFAP2A ARCN1 CDC23

1.08e-0554988938280479
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

YEATS2 KDM5B KMT2D DST ALMS1 BRCA2 CDC23 MYBL2

1.13e-0541888834709266
Pubmed

QKI is a critical pre-mRNA alternative splicing regulator of cardiac myofibrillogenesis and contractile function.

MYH7 DST ANK3

1.73e-052088333397958
Pubmed

BRCA1/2 mutations and FMR1 alleles are randomly distributed: a case control study.

FMR1 BRCA2

1.90e-05388224281364
Pubmed

BRCA1/2 mutations appear embryo-lethal unless rescued by low (CGG n<26) FMR1 sub-genotypes: explanation for the "BRCA paradox"?

FMR1 BRCA2

1.90e-05388222984553
Pubmed

Mouse embryonic stem cells express the cardiac myosin heavy chain genes during development in vitro.

MYH3 MYH7

1.90e-0538821694848
Pubmed

Absence of BRCA/FMR1 correlations in women with ovarian cancers.

FMR1 BRCA2

1.90e-05388225036526
Pubmed

TDP1 is Critical for the Repair of DNA Breaks Induced by Sapacitabine, a Nucleoside also Targeting ATM- and BRCA-Deficient Tumors.

BRCA2 TDP1

1.90e-05388228802254
Pubmed

Identification of three developmentally controlled isoforms of human myosin heavy chains.

MYH3 MYH7

1.90e-0538821691980
Pubmed

The expression of myosin heavy chain (MHC) genes in human skeletal muscle is related to metabolic characteristics involved in the pathogenesis of type 2 diabetes.

MYH2 MYH7

1.90e-05388221470888
Pubmed

Expression and function of K(V)2-containing channels in human urinary bladder smooth muscle.

KCNB1 KCNS3

1.90e-05388222422395
Pubmed

Kv2.1 and electrically silent Kv6.1 potassium channel subunits combine and express a novel current.

KCNA2 KCNB1

1.90e-0538828980147
Pubmed

HIV-1 Tat reduces nephrin in human podocytes: a potential mechanism for enhanced glomerular permeability in HIV-associated nephropathy.

NPHS1 ALB

1.90e-05388217301560
Pubmed

The FMR1 CGG repeat test is not a candidate prescreening tool for identifying women with a high probability of being carriers of BRCA mutations.

FMR1 BRCA2

1.90e-05388224065114
Pubmed

Electrically silent potassium channel subunits from human lens epithelium.

KCNB1 KCNS3

1.90e-05388210484328
Pubmed

Myosin heavy chain gene expression in mouse embryoid bodies. An in vitro developmental study.

MYH3 MYH7

1.90e-0538821939265
Pubmed

Structural and developmental analysis of two linked myosin heavy chain genes.

MYH2 MYH7

1.90e-0538821371481
Pubmed

Genome-wide association study identifies genes that may contribute to risk for developing heroin addiction.

XIRP2 RIMS2

1.90e-05388220520587
Pubmed

Association of BRCA1/2 mutations with FMR1 genotypes: effects on menarcheal and menopausal age.

FMR1 BRCA2

1.90e-05388223528734
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

YEATS2 MYH2 KMT2D FMR1 NFKBIB BSN TFAP2A IGSF3 MYBL2

3.50e-0563888931182584
Pubmed

A common ankyrin-G-based mechanism retains KCNQ and NaV channels at electrically active domains of the axon.

KCNA2 ANK3

3.79e-05488216525039
Pubmed

Evaluation of embryonic and perinatal myosin gene mutations and the etiology of congenital idiopathic clubfoot.

MYH2 MYH3

3.79e-05488220357587
Pubmed

ADAMTS-3, -13, -16, and -19 levels in patients with habitual abortion.

ADAMTS3 ADAMTS13

3.79e-05488228088271
Pubmed

Biochemical characterization of the native Kv2.1 potassium channel.

KCNA2 KCNB1

3.79e-05488216008572
Pubmed

Expression of ADAMTS-2, -3, -13, and -14 in culprit coronary lesions in patients with acute myocardial infarction or stable angina.

ADAMTS3 ADAMTS13

3.79e-05488222205175
Pubmed

Lactoferrin Binds through Its N-Terminus to the Receptor-Binding Domain of the SARS-CoV-2 Spike Protein.

ALB LTF

3.79e-05488239204126
Pubmed

PHF2 regulates sarcomeric gene transcription in myogenesis.

PHF2 MYH7

3.79e-05488238701072
Pubmed

A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.

MYH3 MYH7 DST FMR1 ALMS1 XIRP2 TTC3 VAV2

3.89e-0549788823414517
Pubmed

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

MYH7 KMT2D SF3A3 OBSL1 ALB SIN3A CABIN1 TFAP2A TBX2 MYBL2

6.24e-05857881025609649
Pubmed

Myomesin 3, a novel structural component of the M-band in striated muscle.

MYH2 MYH7

6.30e-05588218177667
Pubmed

Histone deacetylases associated with the mSin3 corepressor mediate mad transcriptional repression.

SIN3A CABIN1

6.30e-0558829150134
Pubmed

Developmental regulation of myosin gene expression in mouse cardiac muscle.

MYH3 MYH7

6.30e-0558822277065
Pubmed

Developmental pattern of mouse skeletal myosin heavy chain gene transcripts in vivo and in vitro.

MYH2 MYH3

6.30e-0558823829126
Pubmed

Multigene family for sarcomeric myosin heavy chain in mouse and human DNA: localization on a single chromosome.

MYH2 MYH3

6.30e-0558826879174
Pubmed

Myosin heavy chain isoforms of the murine masseter muscle during pre- and post-natal development.

MYH2 MYH7

6.30e-05588212919077
Pubmed

Sequential accumulation of mRNAs encoding different myosin heavy chain isoforms during skeletal muscle development in vivo detected with a recombinant plasmid identified as coding for an adult fast myosin heavy chain from mouse skeletal muscle.

MYH2 MYH3

6.30e-0558826196357
Pubmed

K+ current diversity is produced by an extended gene family conserved in Drosophila and mouse.

KCNA2 KCNB1

6.30e-0558822333511
Pubmed

The gamma-aminobutyric acid type A receptor (GABAAR)-associated protein GABARAP interacts with gephyrin but is not involved in receptor anchoring at the synapse.

GABRG2 BSN

6.30e-05588210900017
Pubmed

Sox6 is required for normal fiber type differentiation of fetal skeletal muscle in mice.

MYH2 MYH7

6.30e-05588217584907
Pubmed

Voltage-gated potassium channel genes are clustered in paralogous regions of the mouse genome.

KCNA2 DST KCNB1

6.68e-05318838034307
Pubmed

An Oct4-centered protein interaction network in embryonic stem cells.

YEATS2 KMT2D SIN3A CABIN1 MYBL2

6.83e-0516788520362541
Pubmed

Myosin heavy chain-embryonic regulates skeletal muscle differentiation during mammalian development.

MYH2 MYH3 MYH7

8.08e-053388332094117
Pubmed

The cell proliferation antigen Ki-67 organises heterochromatin.

MYH3 KMT2D DST FMR1 SF3A3 ARCN1 CDC23

8.40e-0541088726949251
Pubmed

Poly(C)-binding protein 1 (Pcbp1) regulates skeletal muscle differentiation by modulating microRNA processing in myoblasts.

MYH3 MYH7

9.43e-05688228381556
Pubmed

Cabin1 represses MEF2-dependent Nur77 expression and T cell apoptosis by controlling association of histone deacetylases and acetylases with MEF2.

SIN3A CABIN1

9.43e-05688210933397
Pubmed

Organization of human and mouse skeletal myosin heavy chain gene clusters is highly conserved.

MYH2 MYH3

9.43e-05688210077619
Pubmed

Loss of the neurodevelopmental Joubert syndrome causing protein, Ahi1, causes motor and muscle development delays independent of central nervous system involvement.

MYH2 MYH7

9.43e-05688230695685
Pubmed

BetaIVSigma1 spectrin stabilizes the nodes of Ranvier and axon initial segments.

KCNA2 ANK3

9.43e-05688215381686
Pubmed

Type 3 and type 1 ryanodine receptors are localized in triads of the same mammalian skeletal muscle fibers.

MYH2 MYH3

9.43e-05688210444070
Pubmed

Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer.

YEATS2 KMT2D ALMS1 ALB GIGYF1

1.08e-0418488532908313
Pubmed

Ion channel expression in the developing enteric nervous system.

KCNA2 ANK3 KCNB1

1.14e-043788325798587
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

PALD1 ANK3 CCDC28B ALKBH2 EIF2B5 SF3A3 OBSL1 MIOS GAN GIGYF1 NEURL4 CDC23

1.23e-041321881227173435
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

YEATS2 ALMS1 BRCA2 MYO9A OBSL1 BSN CDC23 MYBL2

1.25e-0458888838580884
Pubmed

HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.

MYH7 FMR1 SLC12A4 BRCA2 SF3A3 ALB LTF RIMS2 VAV2

1.25e-0475488935906200
Pubmed

Functional proteomics mapping of a human signaling pathway.

KMT2D DST SLC12A4 ANK3 LIMD1 VPS41 TTC3 CUEDC1

1.29e-0459188815231748
Pubmed

The brain expressed x-linked gene 1 (Bex1) regulates myoblast fusion.

MYH2 MYH7

1.32e-04788226586200
Pubmed

Heteromultimeric delayed-rectifier K+ channels in schwann cells: developmental expression and role in cell proliferation.

KCNA2 KCNB1

1.32e-0478829852577
Pubmed

AcvR1-mediated BMP signaling in second heart field is required for arterial pole development: implications for myocardial differentiation and regional identity.

MYH3 MYH7 TBX2

1.45e-044088324680892
Pubmed

Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

FRMPD4 ALMS1 ADAMTS3 CABIN1

1.45e-041048849205841
Pubmed

Impaired OTUD7A-dependent Ankyrin regulation mediates neuronal dysfunction in mouse and human models of the 15q13.3 microdeletion syndrome.

GABRG2 KCNA2 FRMPD4 ANK3 KCNB1

1.48e-0419788536604605
Pubmed

Early Developmental Disruption of Type 2 Deiodinase Pathway in Mouse Skeletal Muscle Does Not Impair Muscle Function.

MYH2 MYH7

1.75e-04888227967605
Pubmed

CFAP43 modulates ciliary beating in mouse and Xenopus.

CFAP43 DNAH1

1.75e-04888231884020
Pubmed

Glomerular mesangial cell recruitment and function require the co-receptor neuropilin-1.

NPHS1 NRP2

1.75e-04888228835419
Pubmed

Neuromuscular junction immaturity and muscle atrophy are hallmarks of the ColQ-deficient mouse, a model of congenital myasthenic syndrome with acetylcholinesterase deficiency.

MYH2 MYH7

1.75e-04888226993635
Pubmed

Genes for skeletal muscle myosin heavy chains are clustered and are not located on the same mouse chromosome as a cardiac myosin heavy chain gene.

MYH3 MYH7

1.75e-0488823864153
Pubmed

An ancient family of embryonically expressed mouse genes sharing a conserved protein motif with the T locus.

ALB TBX2

1.75e-0488827920656
Pubmed

Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.

KDM5B KMT2D FMR1 ALMS1 OBSL1 SIN3A UNC79

1.92e-0446988727634302
Pubmed

The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1.

DST HECW2 ALB NEURL4 CDC23

2.09e-0421288533853758
Pubmed

HOXA5 plays tissue-specific roles in the developing respiratory system.

MYH2 MYH3 MYH7

2.20e-044688328827394
Pubmed

Smad5 knockout mice die at mid-gestation due to multiple embryonic and extraembryonic defects.

TFAP2A TBX2

2.25e-04988210079226
Pubmed

GASP-2 overexpressing mice exhibit a hypermuscular phenotype with contrasting molecular effects compared to GASP-1 transgenics.

MYH2 MYH7

2.25e-04988231960486
Pubmed

Loss of the collagen IV modifier prolyl 3-hydroxylase 2 causes thin basement membrane nephropathy.

NPHS1 P3H2

2.25e-04988235499085
Pubmed

Muscle-specific gene expression during myogenesis in the mouse.

MYH3 MYH7

2.25e-0498827787235
Pubmed

Foxp2 regulates gene networks implicated in neurite outgrowth in the developing brain.

NELL2 NRP2

2.25e-04988221765815
Pubmed

KDM5B regulates embryonic stem cell self-renewal and represses cryptic intragenic transcription.

KDM5B SIN3A

2.25e-04988221448134
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

DST FMR1 TLL1 EIF2B5 OBSL1 OGFOD1 SIN3A GIGYF1

2.47e-0465088838777146
Pubmed

The expression of myosin genes in developing skeletal muscle in the mouse embryo.

MYH3 MYH7

2.81e-04108822211821
Pubmed

Brahma links the SWI/SNF chromatin-remodeling complex with MeCP2-dependent transcriptional silencing.

FMR1 SIN3A

2.81e-041088215696166
InteractionNCKAP5 interactions

BRCA2 HECW2 NEURL4 VAV2

1.06e-0532874int:NCKAP5
InteractionWWTR1 interactions

YEATS2 KMT2D ALMS1 ANK3 LIMD1 SIN3A TFAP2A ARCN1 CDC23 TBX2

1.39e-054228710int:WWTR1
Cytoband17q23.2

EFCAB3 CUEDC1 TBX2

3.56e-053388317q23.2
Cytoband1p13

KCNA2 IGSF3

4.85e-04178821p13
GeneFamilyPotassium voltage-gated channels

KCNG2 KCNA2 KCNB1 KCNS3

7.45e-0640574274
GeneFamilyMyosin heavy chains

MYH2 MYH3 MYH7

1.32e-05155731098
GeneFamilyADAM metallopeptidases with thrombospondin type 1 motif

ADAMTS3 ADAMTS20 ADAMTS13

2.78e-051957350
GeneFamilyPHD finger proteins|Lysine demethylases

PHF2 KDM5B

2.58e-0324572485
GeneFamilyPHD finger proteins

PHF2 KDM5B KMT2D

2.87e-039057388
CoexpressionNABA_ECM_REGULATORS

ADAMTS3 P3H2 TLL1 ADAMTS20 OGFOD1 ADAMTS13 ADAM32

1.58e-05238887M3468
CoexpressionNABA_ECM_REGULATORS

ADAMTS3 P3H2 TLL1 ADAMTS20 OGFOD1 ADAMTS13 ADAM32

1.76e-05242887MM17062
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HGABA

GABRG2 FRMPD4 ANK3 ADAMTS3 TLL1 SIN3A GIGYF1 BSN TTC3 RIMS2 UNC79 VAV2 IGSF3 NRP2

1.82e-0511068814M39071
CoexpressionGSE45365_HEALTHY_VS_MCMV_INFECTION_CD11B_DC_UP

KCNG2 MYH3 ALMS1 CCDC28B CABIN1 CUEDC1

4.31e-05189886M9978
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle_emap-6706_top-relative-expression-ranked_1000

MYH3 FBLN2 DST ERO1B ADAMTS3 SUSD5 ADAMTS20 ALB RIMS2 TFAP2A CDC23 IGSF3 NRP2

1.11e-057698513gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle_1000
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GABRG2 FRMPD4 ANK3 HECW2 TTC3 RIMS2 UNC79

1.35e-071988870ff30edfd3c133a42e8cb96e1631a1143215f808
ToppCellNeuronal|World / cells hierarchy compared to all cells using T-Statistic

GABRG2 FRMPD4 ANK3 KCNB1 HECW2 RIMS2 UNC79

1.45e-0720088748d801219bc771d6c7e151dc88ca4c179988de85
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Lmo1_Fam159b|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

FBLN2 ADAMTS3 LTF VAV2 IGSF3 NRP2

4.97e-071488869205b26e0d042b342cc643cda0f4f3f8bb392d00
ToppCellfacs-Diaphragm-Limb_Muscle-24m|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LTBP2 RP1 LTF RIMS2 UNC79 DNAH1

1.08e-0616988612bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCell3'-GW_trimst-2-LargeIntestine-Neuronal-Glial_immature-Differentiating_glia|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NELL2 NCEH1 LRRTM1 BSN UNC79 TFAP2A

1.41e-061778860417460bdb012bc43d7254377fa53d79cdab3f34
ToppCellmild-Myeloid-pDC|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

PALD1 KCNG2 P3H2 OBSL1 CUEDC1 MYBL2

1.56e-0618088638614155fa537d0defda914c531c697be0ef06d8
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MYO9A CYP24A1 RP1 CFAP43 RIMS2 VAV2

1.88e-06186886f0c8de4f6ae9047b9108a47a2af8c5f42bc103b0
ToppCell5'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature-Differentiating_glia|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NELL2 FBLN2 DST LRRTM1 TFAP2A TBX2

2.33e-06193886d5930f7bd9b299f792212d40a3272a37adf64a82
ToppCell3'-Pediatric_IBD-SmallIntestine-Neuronal-Glial_mature-Adult_Glia|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FBLN2 DST ANK3 P3H2 LRRTM1 TFAP2A

2.40e-06194886d429bb5e422a07bd92f0dc48cd51528e8b7d9a72
ToppCell3'-Pediatric_IBD-SmallIntestine-Neuronal|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FBLN2 DST ANK3 P3H2 LRRTM1 TFAP2A

2.40e-06194886bffdf6db0bf3fb338e7bb0789ae7dcde1fce0094
ToppCell3'-Pediatric_IBD-SmallIntestine-Neuronal-Glial_mature|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FBLN2 DST ANK3 P3H2 LRRTM1 TFAP2A

2.40e-06194886408dfc7060095972a54ae37ae8105521df6fbbee
ToppCellILEUM-non-inflamed-(9)_Enteric_neurons|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

FBLN2 DST ANK3 P3H2 LRRTM1 TFAP2A

2.55e-06196886998aa523555ed6bc9c1b5cacbf7ba77c7b218e6b
ToppCellILEUM-non-inflamed-(9)_Neuro_cell|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

FBLN2 DST ANK3 P3H2 LRRTM1 TFAP2A

2.55e-061968862b08cd6730119d5dea0152709ab8de580b66cd3c
ToppCellSomatosensory_Cortex_(S1)-Neuronal|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GABRG2 FRMPD4 KCNB1 TTC3 RIMS2 UNC79

2.70e-06198886c01091ef18e096d792ea2a7a715764a5b215355f
ToppCellprimary_auditory_cortex_(A1C)-Neuronal|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GABRG2 FRMPD4 KCNB1 TTC3 RIMS2 UNC79

2.70e-061988866d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCellE18.5-samps-Mesenchymal-Myofibroblast-myofibroblast_-_mature_-_B|E18.5-samps / Age Group, Lineage, Cell class and subclass

ALMS1 KCNS3 ASB1 UNC79 DNAH1

7.78e-06137885b553958e7e6dcd887d860e34d3983cbb85cefaa6
ToppCell10x5'-Liver-Myeloid_Mac-Intestinal_macrophages|Liver / Manually curated celltypes from each tissue

PALD1 DST P3H2 NCEH1 NRP2

1.46e-051568859a897fc79c4fae94c5f2e9012d65297f9225e5e3
ToppCellfacs-Pancreas-Exocrine-24m-Epithelial-pancreatic_acinar_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NPHS1 MYH2 MYO9A ADAMTS20 LTF

1.70e-05161885b9a17f41426bf715f30bf544a6795afaf37a3aa6
ToppCellfacs-Pancreas-Exocrine-24m-Epithelial-pancreatic_acinar_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NPHS1 MYH2 MYO9A ADAMTS20 LTF

1.70e-05161885f7a89c481f789f624102857be722c95fbeb47595
ToppCellAdult-Mesenchymal-myofibroblast_cell-D231|Adult / Lineage, Cell type, age group and donor

KCNS3 LTBP2 ADAM32 NEURL4 TBX2

1.86e-051648853d8ff70fe5582d1fb56b338be8b76fa1428b3657
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MYO9A CYP24A1 RP1 LTF RIMS2

1.86e-051648851cb5fbd7050650047ad6f2ca792118e98d58d22b
ToppCellInfluenza_Severe-pDC|World / Disease group and Cell class

PALD1 KCNG2 P3H2 OBSL1 MYBL2

1.97e-05166885bd25ce4c03c3d6cd9d986b9be1d355da52f0f2d7
ToppCellmild_COVID-19_(asymptomatic)-pDC|World / disease group, cell group and cell class (v2)

PALD1 KCNG2 FBLN2 P3H2 SUSD5

2.03e-05167885bf08f17965a4dd03f371b4ed0ab0d5e62ed61307
ToppCellCerebellum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)|Cerebellum / BrainAtlas - Mouse McCarroll V32

FRMPD4 ADAMTS3 FAM131C UNC79 TFAP2A

2.03e-051678859efb9511a211d0824bb97f82c1a5860c43d2138f
ToppCellCerebellum-Neuronal-Inhibitory|Cerebellum / BrainAtlas - Mouse McCarroll V32

FRMPD4 ADAMTS3 FAM131C UNC79 TFAP2A

2.03e-05167885904c613aac3f9919a432b110bb1dcc832b5aec0a
ToppCellmild_COVID-19_(asymptomatic)-pDC|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)

PALD1 KCNG2 FBLN2 P3H2 SUSD5

2.09e-05168885968405ea56f7d001ef83ff9274610923c3b2d55d
ToppCellPND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FBLN2 TLL1 VPS41 TFAP2A CUEDC1

2.09e-0516888532e4d82efaccf336d347e4063253c3635a3ec672
ToppCellP07-Epithelial-epithelial_progenitor_cell-epithelial_unknown_3|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

NELL2 KCNA2 ADAMTS20 LRRTM1 TFAP2A

2.34e-051728858d6a2a0d5f63b09a5a304a77e600a647f87e9de4
ToppCellmild_COVID-19-pDC|World / disease group, cell group and cell class (v2)

PALD1 KCNG2 P3H2 OBSL1 MYBL2

2.34e-05172885dab2f1a05c7df58d9387b13271b3f1f1583f9ac3
ToppCell5'-GW_trimst-2-LargeIntestine-Neuronal-Glial_immature-Differentiating_glia|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NELL2 DST LRRTM1 TFAP2A TBX2

2.47e-05174885412ccc099028a372b9d953363984c2da54b2187f
ToppCellmild_COVID-19-pDC|mild_COVID-19 / disease group, cell group and cell class (v2)

PALD1 KCNG2 P3H2 OBSL1 MYBL2

2.54e-05175885b87f279a7519710146c49d6acccb0adedc195965
ToppCellILEUM-inflamed-(9)_Enteric_neurons|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

DST ANK3 KCNS3 LRRTM1 TFAP2A

2.75e-05178885d9142151819afb0dc22bfb32a9c9dba5f553067d
ToppCellILEUM-inflamed-(9)_Neuro_cell|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

DST ANK3 KCNS3 LRRTM1 TFAP2A

2.75e-05178885611504b0a9e6318b18fba83787b03f9245c82252
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Myeloid-Dendritic-plasmacytoid_dendritic_cell|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PALD1 KCNG2 P3H2 CUEDC1 MYBL2

2.83e-05179885124da6f882968dc0d05f3edd8f3b4d61617cc214
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Myeloid-Dendritic-plasmacytoid_dendritic_cell-DC_c4-LILRA4|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PALD1 KCNG2 P3H2 CUEDC1 MYBL2

2.83e-05179885edc5ef693dc4e7ea70717b77fb908fc784dce3a2
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GABRG2 TLL1 TTC3 RIMS2 UNC79

2.90e-05180885f6a2208960d0df1500c974cc44c3c054cd7475a9
ToppCelldroplet-Limb_Muscle-nan-3m-Macroglial-Schwann_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNA2 ANK3 ADAMTS20 LRRTM1 UNC79

3.14e-051838852cf36ad89584eb9f8b04de52a1b511b7f3527884
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Myeloid-Dendritic-plasmacytoid_dendritic_cell-DC_c4-LILRA4|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PALD1 KCNG2 P3H2 CUEDC1 MYBL2

3.14e-051838853b123571e10c132227aff65648b4b3c6acb4bd00
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Myeloid-Dendritic-plasmacytoid_dendritic_cell|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PALD1 KCNG2 P3H2 CUEDC1 MYBL2

3.14e-05183885df6fd0927b6e4cf9a1583969a68096e4bccfbace
ToppCelldroplet-Limb_Muscle-nan-3m-Macroglial|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNA2 ANK3 ADAMTS20 LRRTM1 UNC79

3.14e-0518388598fee6838acfaee5e2e449ba088764ec06b8bc57
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRMPD4 XIRP2 ADAMTS20 UNC79 DNAH1

3.22e-051848852cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRMPD4 XIRP2 ADAMTS20 UNC79 DNAH1

3.22e-05184885ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRMPD4 XIRP2 ADAMTS20 UNC79 DNAH1

3.22e-051848852b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellnormal-na-Myeloid-plasmacytoid_dendritic_cell-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

PALD1 P3H2 ALB CUEDC1 MYBL2

3.31e-051858853091870a5bf8ecb963e560b47c8502bae367416c
ToppCell3'-GW_trimst-1-LargeIntestine-Mesenchymal-mesothelial_cell-Mesothelium_(RGS5+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NPHS1 ANK3 ADAMTS3 TLL1 LRRTM1

3.31e-0518588511fbea1eb1d9a3e4480d0d2b0f7b02e2866b8142
ToppCelldroplet-Liver-Hepatocytes-18m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HECW2 KCNS3 TTC3 NRP2 TBX2

3.40e-0518688537860daeecd6d412bd3797f30496a56da667fbd1
ToppCellControl-Endothelial_cells-Endothelial_cells_(other)|Control / group, cell type (main and fine annotations)

PALD1 HECW2 TLL1 GRK5 TBX2

3.40e-05186885c6075fe84226b370c5139066793844ad33ae2db1
ToppCelldroplet-Liver-Hepatocytes-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HECW2 KCNS3 TTC3 NRP2 TBX2

3.40e-0518688560830822d3de3147816693404fd03392e04c2b8e
ToppCellfacs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea-|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MYH2 MYH3 HECW2 LRRTM1 UNC79

3.40e-05186885bdc87e4631a8ea73e262e541aa84a28f24c94b00
ToppCelldroplet-Liver-Hepatocytes-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HECW2 KCNS3 TTC3 NRP2 TBX2

3.40e-05186885baebeffdd426ce767190ddefc857cc78e6a58d36
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TLL1 BSN RIMS2 UNC79 TFAP2A

3.48e-05187885ef3c85c01bc3da408ae288b6e3096ad888a12e63
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MYO9A RP1 CFAP43 RIMS2 VAV2

3.48e-05187885c31130fc2f9f882944b2ba366a034a03f051c4b9
ToppCellHealthy_donor-pDC|World / disease group, cell group and cell class (v2)

PALD1 KCNG2 P3H2 FAM131C MYBL2

3.48e-05187885aa2cc54487d3c5045ac0c93560944c5a55878e27
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MYO9A CYP24A1 RP1 RIMS2 VAV2

3.57e-05188885af740fa78542438fdff627ea1f74f4eee43316be
ToppCell10x3'2.3-week_12-13-Mesenchymal_fibro-stroma-endosteal_fibroblast|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

NELL2 ANK3 TLL1 GRK5 FAM131C

3.66e-05189885c392491aabe8a3e90974ab2ea123bbbe5200439d
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DST NCEH1 RP1 RIMS2 NRP2

3.66e-051898858c8ca3b30d9be6c854615459a7bfba82b427c8bc
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DST NCEH1 RP1 RIMS2 NRP2

3.66e-051898855d902a4660a27548764bf04c6de152b565da835c
ToppCellControl-Myeloid-pDC|Control / Disease group, lineage and cell class

PALD1 KCNG2 P3H2 CUEDC1 MYBL2

3.66e-0518988546770b99da42f11f10cfc67cea8562342d60b867
ToppCellPBMC-Control-Myeloid-pDC|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

PALD1 KCNG2 P3H2 CUEDC1 MYBL2

3.76e-05190885adffa93635da10251f28b2089fd96b189775c8b4
ToppCellPBMC-Control-Myeloid-pDC-pDC|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PALD1 KCNG2 P3H2 CUEDC1 MYBL2

3.76e-051908859a91bf1ea105029e6412d0d9060bca325299ce26
ToppCellPBMC-Control-Myeloid-pDC-pDC|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

PALD1 KCNG2 P3H2 CUEDC1 MYBL2

3.76e-0519088539c8ddc2639bf3e986dae11fbae61a735614b604
ToppCellPBMC-Control-Myeloid-pDC|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PALD1 KCNG2 P3H2 CUEDC1 MYBL2

3.76e-051908852c1c079fd411c03bc3f383aa927eea9446716960
ToppCell(5)_Fibroblasts-(5)_Fibroblast-C_(Myofibroblast)|(5)_Fibroblasts / Lung cell shreds - cell class (v4) and cell subclass (v4)

NELL2 DST KCNS3 LTBP2 TBX2

3.76e-0519088571e112dfb8c3190fe0286b45a046ea789eb6a8db
ToppCellPBMC-Control-Myeloid-pDC-pDC-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PALD1 KCNG2 P3H2 CUEDC1 MYBL2

3.76e-05190885a95aea3aa707fc4574810706341a5f32b3d00209
ToppCellPBMC-Control-Myeloid-pDC-pDC-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

PALD1 KCNG2 P3H2 CUEDC1 MYBL2

3.76e-0519088518dfa84c62dcf081ce9958a71e76a394ec0968e4
ToppCell3'_v3-lymph-node_spleen-Myeloid_Dendritic|lymph-node_spleen / Manually curated celltypes from each tissue

PALD1 KCNG2 P3H2 CUEDC1 NRP2

3.85e-05191885c3ff4342e0eea1e1f071b1fbca14a6dd4df0c696
ToppCellCOVID-19_Moderate-pDC|World / disease group, cell group and cell class

PALD1 KCNG2 P3H2 CUEDC1 MYBL2

3.85e-0519188593adfbc0b22f6006d6d5ad67a99e33cbe9e1dfe9
ToppCellCOVID-19_Moderate-pDC|COVID-19_Moderate / disease group, cell group and cell class

PALD1 KCNG2 P3H2 CUEDC1 MYBL2

3.85e-051918859d0ffa65c547e20b4076fd97776d7738cbd453ec
ToppCellHealthy-pDC|World / disease group, cell group and cell class

PALD1 KCNG2 P3H2 CUEDC1 MYBL2

3.85e-051918856e1d825dc33b915b95f13ccd237a552160a4be98
ToppCell3'-Child09-12-SmallIntestine-Neuronal-Glial_mature|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FBLN2 ANK3 P3H2 LRRTM1 TFAP2A

3.95e-05192885ac507fd7cf3b3e521a15ef03bb4e81eb23807985
ToppCell3'-Child09-12-SmallIntestine-Neuronal|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FBLN2 ANK3 P3H2 LRRTM1 TFAP2A

3.95e-0519288524f40dadec04f4f99c31000fa9f09d07148fa190
ToppCell3'-Child09-12-SmallIntestine-Neuronal-Glial_mature-Adult_Glia|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FBLN2 ANK3 P3H2 LRRTM1 TFAP2A

3.95e-0519288571e04e197825856c6d4278fc76c58ab17ffa2387
ToppCellHealthy-pDC|Healthy / disease group, cell group and cell class

PALD1 KCNG2 P3H2 CUEDC1 MYBL2

3.95e-0519288533d695a28d22b4af111df9591830a33bb7ef7b2d
ToppCell3'-GW_trimst-1.5-LargeIntestine-Neuronal|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NELL2 FBLN2 DST TFAP2A TBX2

4.05e-0519388566af80f4b51e1ce97b6fb7c630dc5f95bfa7e7d4
ToppCellVE-pDC-|VE / Condition, Cell_class and T cell subcluster

PALD1 KCNG2 P3H2 CUEDC1 MYBL2

4.05e-05193885583724de588fcde3aeda056138c522dc0225a387
ToppCellcritical-Lymphoid-NK|Lymphoid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DST TFAP2A IGSF3 NRP2 TBX2

4.05e-051938856be11fef87af04ee7a3cc223882ccd4077caded9
ToppCellThalamus-Neuronal|Thalamus / BrainAtlas - Mouse McCarroll V32

GABRG2 FRMPD4 BSN TTC3 UNC79

4.05e-05193885712a4acd1167e43543950bc819ff11984e6f718d
ToppCellVE-pDC|VE / Condition, Cell_class and T cell subcluster

PALD1 KCNG2 P3H2 CUEDC1 MYBL2

4.05e-05193885bb759dc9ef0ec41d655002f59021d62d62d44289
ToppCell368C-Fibroblasts-Fibroblast-G-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

DST KCNS3 LTBP2 NRP2 TBX2

4.15e-05194885d9eec28fa7b255c0ec023276dd955f1e276e7159
ToppCell(5)_Fibroblast-C_(Myofibroblast)|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

FBLN2 DST KCNS3 LTBP2 TBX2

4.15e-0519488529a72e565c19407bbd198cfbc2a78106fe830d05
ToppCell368C-Fibroblasts-Fibroblast-G|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

DST KCNS3 LTBP2 NRP2 TBX2

4.15e-05194885e4d7e9709ce42d4610e44d3445927eefbcbb9eff
ToppCell3'-Child04-06-SmallIntestine-Neuronal|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FBLN2 ANK3 P3H2 LRRTM1 TFAP2A

4.25e-051958858d286622f86c844d1b06a106ee4a3f813eba05bb
ToppCell3'-Child04-06-SmallIntestine-Neuronal-Glial_mature|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FBLN2 ANK3 P3H2 LRRTM1 TFAP2A

4.25e-051958854193e58788e90c3d1049ef5cf9800a8c4d8ac354
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GABRG2 NELL2 FRMPD4 KCNB1 RIMS2

4.25e-051958852e1df01bf6e4e98e6cd9fb50926e34c5077b8666
ToppCell3'-Child04-06-SmallIntestine-Neuronal-Glial_mature-Adult_Glia|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FBLN2 ANK3 P3H2 LRRTM1 TFAP2A

4.25e-05195885359b9d791e26844675c3c60cf69d8ab69c2cf400
ToppCellMid-temporal_gyrus_(MTG)-Neuronal|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GABRG2 FRMPD4 KCNB1 RIMS2 UNC79

4.36e-05196885676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCellInfluenza-Influenza_Severe-Myeloid-pDC|Influenza_Severe / Disease, condition lineage and cell class

PALD1 KCNG2 DST OBSL1 MYBL2

4.46e-05197885e8e6f71e6dc8a695e4321a18543c1df63dd62f3e
ToppCell5'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NELL2 FBLN2 DST LRRTM1 TFAP2A

4.57e-0519888550dfe6efca76ea9683a19b6bff59cb5030d346f1
ToppCell3'-GW_trimst-1.5-SmallIntestine-Neuronal-Glial_immature|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NELL2 FBLN2 DST LRRTM1 TFAP2A

4.57e-051988855b9a7b9f53a3d9cf8d6e6a7c1c94514b22cf9fa8
ToppCell367C-Fibroblasts-Fibroblast-C_(Myofibroblast)|367C / Donor, Lineage, Cell class and subclass (all cells)

FBLN2 DST KCNS3 LTBP2 TBX2

4.57e-05198885a9afedbc0556faf4a46f7bf28f4a9adb3bc859d8
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GABRG2 NELL2 FRMPD4 RIMS2 UNC79

4.57e-051988858ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCellnormal_Lung-Fibroblasts-COL13A1+_matrix_FBs|Fibroblasts / Location, Cell class and cell subclass

DST KCNS3 LTBP2 NRP2 TBX2

4.57e-05198885e0e47cf65774191981840b22905b2094b95abe0f
ToppCellBronchus_Control_(B.)-Endothelial-TX|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

KCNG2 DST FRMPD4 EIF2B5 RIMS2

4.57e-05198885feac39036b5c0ab97b524cc366286942d136d42f
ToppCell367C-Fibroblasts-Fibroblast-C_(Myofibroblast)-|367C / Donor, Lineage, Cell class and subclass (all cells)

FBLN2 DST KCNS3 LTBP2 TBX2

4.57e-051988857b5350768f306ec528e271d2ac4470bf668ec6f0
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-1_mon-Neuronal|1_mon / Sample Type, Dataset, Time_group, and Cell type.

GABRG2 NELL2 ANK3 TTC3 NRP2

4.68e-05199885f94307958cead25d38103fcbb35fa45011de1687
ToppCell5'-GW_trimst-2-LargeIntestine-Neuronal|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NELL2 FBLN2 DST LRRTM1 TFAP2A

4.68e-051998855f350d9c7da9ac111bf22623dd4fed7f7983c9fc
ToppCellLPS_IL1RA-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

GABRG2 KCNG2 ANK3 LTBP2 ADAMTS13

4.68e-051998856b3a0e5d52a30d0eed30e6a670f5b53bc233f70c
ToppCell3'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NELL2 FBLN2 DST LRRTM1 TFAP2A

4.68e-051998851761669ec514fdb4175042f11b9a31fa5687fc2b
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW09-Neuronal|GW09 / Sample Type, Dataset, Time_group, and Cell type.

GABRG2 NELL2 ANK3 TTC3 UNC79

4.79e-05200885e9eb348a66011d8aace4331f84690ae27cb0d061
ToppCell5'-GW_trimst-2-LargeIntestine-Neuronal-Glial_immature|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NELL2 FBLN2 DST LRRTM1 TFAP2A

4.79e-05200885363a8cebf2ace820661bcb87c7941f6671f8e5f3
Diseaseautosomal dominant hyaline body myopathy (implicated_via_orthology)

MYH2 MYH3 MYH7

2.83e-0610863DOID:0111269 (implicated_via_orthology)
Diseasedistal arthrogryposis type 2B3 (implicated_via_orthology)

MYH2 MYH3 MYH7

2.83e-0610863DOID:0111602 (implicated_via_orthology)
Diseasedistal arthrogryposis type 1 (implicated_via_orthology)

MYH2 MYH3 MYH7

2.83e-0610863DOID:0111596 (implicated_via_orthology)
Diseasedilated cardiomyopathy 1S (implicated_via_orthology)

MYH2 MYH3 MYH7

2.83e-0610863DOID:0110454 (implicated_via_orthology)
Diseasecongenital myopathy 6 (implicated_via_orthology)

MYH2 MYH3 MYH7

2.83e-0610863DOID:0080719 (implicated_via_orthology)
Diseaseinclusion body myositis (implicated_via_orthology)

MYH2 MYH3 MYH7

2.83e-0610863DOID:3429 (implicated_via_orthology)
Diseasedistal arthrogryposis type 2A (implicated_via_orthology)

MYH2 MYH3 MYH7

2.83e-0610863DOID:0111605 (implicated_via_orthology)
Diseasefamilial hypertrophic cardiomyopathy (implicated_via_orthology)

MYH2 MYH3 MYH7

2.83e-0610863DOID:0080326 (implicated_via_orthology)
Diseasedistal myopathy (implicated_via_orthology)

MYH2 MYH3 MYH7

5.16e-0612863DOID:11720 (implicated_via_orthology)
Diseasemyotonia congenita (implicated_via_orthology)

MYH2 MYH3 MYH7

5.16e-0612863DOID:2106 (implicated_via_orthology)
Diseaserestrictive cardiomyopathy (implicated_via_orthology)

MYH2 MYH3 MYH7

6.69e-0613863DOID:397 (implicated_via_orthology)
Diseasedistal arthrogryposis (implicated_via_orthology)

MYH2 MYH3 MYH7

1.06e-0515863DOID:0050646 (implicated_via_orthology)
Diseaseneuropilin-2 measurement

NELL2 NRP2

2.51e-053862EFO_0801836
Diseaseneuropathy, type 2 diabetes mellitus

NELL2 NRP2

2.51e-053862EFO_0004149, MONDO_0005148
Diseasedilated cardiomyopathy (implicated_via_orthology)

MYH2 MYH3 MYH7 LTBP2

8.98e-0580864DOID:12930 (implicated_via_orthology)
DiseaseKidney Diseases

NPHS1 THG1L ALB TFAP2A

1.30e-0488864C0022658
Diseasefibroblast growth factor 23 measurement

CYP24A1 ADAMTS13 TBX2

2.71e-0443863EFO_0009381
Diseaseesophagus squamous cell carcinoma (is_implicated_in)

KMT2D BRCA2 CYP24A1

3.10e-0445863DOID:3748 (is_implicated_in)
Diseaseheart disease (is_marker_for)

MYH7 ALB

3.72e-0410862DOID:114 (is_marker_for)
Diseasemyopathy (implicated_via_orthology)

MYH2 MYH3 MYH7

3.76e-0448863DOID:423 (implicated_via_orthology)
Diseaseautism spectrum disorder (implicated_via_orthology)

KDM5B FMR1 RIMS2 NRP2

1.04e-03152864DOID:0060041 (implicated_via_orthology)
Diseasecancer (implicated_via_orthology)

DST BRCA2 THG1L SIN3A TBX2

1.14e-03268865DOID:162 (implicated_via_orthology)
Diseasecardiomyopathy (implicated_via_orthology)

MYH2 MYH3 MYH7

1.18e-0371863DOID:0050700 (implicated_via_orthology)
DiseaseFebrile seizure (within the age range of 3 months to 6 years)

GABRG2 BSN

1.25e-0318862HP_0002373
Diseaseepilepsy (implicated_via_orthology)

GABRG2 KCNA2 SLC12A4 BSN

1.34e-03163864DOID:1826 (implicated_via_orthology)
DiseaseCongenital Myasthenic Syndromes, Presynaptic

DPAGT1 MYO9A

1.39e-0319862C0751884
Diseaseinosine measurement

GMCL2 CUEDC1

1.39e-0319862EFO_0010503
DiseaseArthrogryposis

MYH3 MYO9A

1.70e-0321862C0003886
Diseasecongestive heart failure (is_marker_for)

GRK5 LTBP2 ALB

1.79e-0382863DOID:6000 (is_marker_for)
Diseasecongenital heart disease (is_implicated_in)

MYH7 TLL1

2.22e-0324862DOID:1682 (is_implicated_in)
DiseaseIschemic stroke, coronary artery disease

ADAMTS3 KCNS3 RP1

2.49e-0392863EFO_0001645, HP_0002140

Protein segments in the cluster

PeptideGeneStartEntry
YKDGCDHIGEHRDDE

ALKBH2

161

Q6NS38
DIYSCGEIVEHLEES

CDC23

496

Q9UJX2
SREDLDVCKEHYDNL

CFAP43

1266

Q8NDM7
HGDLLECADDRADLA

ALB

271

P02768
CEDTRLHDAAYVGDL

ASB1

36

Q9Y576
RYDDSRDHFCELDDE

ERO1B

156

Q86YB8
VEEEAGRELDSDSHY

ALMS1

46

Q8TCU4
TDNIKYEDCEDRHDG

TFAP2A

6

P05549
YDGDCHDLDARCESV

ADAM32

491

Q8TC27
REACSYTIHAEGDER

ACSF3

396

Q4G176
YCARAHGEDDGEEIL

ADAMTS13

976

Q76LX8
DALDRIADESYCAHL

ADAMTS20

1181

P59510
ARHDCDLLREQYEEE

MYH7

1336

P12883
SLREEAVLECDGHTY

PALD1

546

Q9ULE6
CDLSDLEYLDEEFHQ

HECW2

1341

Q9P2P5
QLEDSGEYLCEIDDE

OBSL1

961

O75147
YEFTDALLCHDDELE

OGFOD1

146

Q8N543
LHIEACDLSDDAEYE

NPHS1

96

O60500
DTYDPEADHECCERV

KCNA2

21

P16389
DVHDYIRSCLGDTLE

GIGYF1

936

O75420
ELNDEDGHRCYPLED

LIMD1

636

Q9UGP4
GYIRIDDYSCTEHDE

NELL2

471

Q99435
VCEDELDLQHSGSYL

GPR179

646

Q6PRD1
EDVLDAVYAFHLCED

LRRTM1

351

Q86UE6
LLDGDDRDCLHPEDY

DST

2416

Q03001
DRDCLHPEDYDTLQE

DST

2421

Q03001
GDSEDGCLEREEYLL

FAM13B

406

Q9NYF5
EEGYILDDSHCVVSD

BSN

3556

Q9UPA5
HCESEIYEAAAGDLI

CCNYL2

26

Q5T2Q4
DGVEVRYDLLDCHIS

EIF2B5

236

Q13144
DEGDEYDDIVVHSSR

NFKBIB

321

Q15653
VELEGDCRDDHVFSL

DPAGT1

211

Q9H3H5
YQLAEDGHTCTDIDE

FBLN2

971

P98095
GHDDLLRVCDDYDVS

KCNG2

51

Q9UJ96
SSRHDCDLLREQYEE

MYH2

1341

Q9UKX2
YILTCEHDVLRDDGI

NCEH1

341

Q6PIU2
LDDVEGHACDEDFRG

CUEDC1

356

Q9NWM3
HDCKYDFIEIRDGDS

NRP2

81

O60462
TCHSEEAILELCDDY

KCNS3

46

Q9BQ31
EDRLLLCDGCDDSYH

KDM5B

321

Q9UGL1
EGACHALEEYAERLQ

METTL25B

316

Q96FB5
AYLLCHPDDEDVLDN

P3H2

331

Q8IVL5
DCDDGIGVVSDYRHD

RIMS2

976

Q9UQ26
DTDYGILDEAIREAC

DNAH1

1816

Q9P2D7
DFHYRESDLEGLDDL

ADAMTS3

216

O15072
DEDTCTFHIYGEDQD

FMR1

256

Q06787
HITDLQARDAGEYEC

IGSF3

106

O75054
HDSLLEVCDDYSLDD

KCNB1

66

Q14721
RCEGDGDEEEWLIHY

CABIN1

1196

Q9Y6J0
AGCYEALDDSEDILH

BRCA2

1891

P51587
DELCDERGHVEDLYS

CYP24A1

191

Q07973
LHDICYAENTDDAED

FRMPD4

736

Q14CM0
PEADESVARLCDYHL

FRMPD4

1181

Q14CM0
ESRFCDAHLVLDGEE

GAN

26

Q9H2C0
AEDEHYCCLPDELRE

FAM131C

131

Q96AQ9
HLQERDEEYGYECLD

GABRG2

396

P18507
IEYHDDELSELRGES

ANK3

2446

Q12955
LCASDLEEYDAQEGH

LTBP2

1371

Q14767
YAAEILCGLEDLHRE

GRK5

291

P34947
RLHFSLDVCGEEEDD

CCDC28B

131

Q9BUN5
HDVYNELKCADIDRD

EFCAB3

86

Q8N7B9
PEYCRALEENEISEH

ARCN1

91

P48444
EYCEFSLDELQEGDH

NEURL4

421

Q96JN8
HRLEEHEAETYEDGF

LRRC19

306

Q9H756
EELEDGESYLCSHGR

RP1

96

P56715
GDELLVECHYQTLDR

MOXD2P

436

A6NHM9
DICQDDDSIHLESIY

MUC17

4451

Q685J3
ACGKDEAEAHIDYED

SUSD5

196

O60279
LDDYEEEQDHLDACF

PHF2

856

O75151
DLSDEAERDEYELLC

LTF

236

P02788
ECAYDHLEVFDGETE

TLL1

826

O43897
EEGRYCICEDENHEV

RNF113B

231

Q8IZP6
RCEDLDELHYQDTDS

MYBL2

6

P10244
YCDPDSHREEHEEEG

GMCL2

61

Q8NEA9
EEHIYRCEDERFELD

SIN3A

606

Q96ST3
SSRHDCDLLREQYEE

MYH3

1336

P11055
VDYGERAELDDSDGH

SLC12A4

26

Q9UP95
IYCLLHENDGDTIER

XIRP2

1516

A4UGR9
GAPACHRLKEEEDEY

TDP1

131

Q9NUW8
GRHLYECTEEENDNS

MIOS

371

Q9NXC5
LYEEHCKPERDGAES

TBX2

306

Q13207
EYVRDFEADDTCLAH

THG1L

36

Q9NWX6
VADYALLEDCPHVDD

TTC3

11

P53804
ECRDYHLEYSEGESL

VPS41

331

P49754
TDEEGYGRYLDLHDC

SF3A3

131

Q12874
VYRSLEELADEHDLG

VAV2

141

P52735
EELADEHDLGEDIYD

VAV2

146

P52735
DVELHRHSLGEDCIY

YEATS2

326

Q9ULM3
DKCHDCGAILEEYDE

UNC79

2006

Q9P2D8
EHSEGAAYLEEARCA

KMT2D

216

O14686
DCFTVEGEDLRHDFE

MYO9A

386

B2RTY4