Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
HumanPheno	Accessory carpal bones	FLNA FLNB	9.25e-06	2	16	2	HP:0004232
HumanPheno	Bipartite calcaneus	FLNA FLNB	9.25e-06	2	16	2	HP:0008127
HumanPheno	Flat face	HSPG2 FLNA FLNB SUMF1 PEX1	1.29e-05	106	16	5	HP:0012368
HumanPheno	Limitation of joint mobility	HSPG2 FLNA FLNB COL12A1 DST WFS1 SUMF1 IL2RA	1.76e-05	432	16	8	HP:0001376
HumanPheno	Pulmonary hypoplasia	HSPG2 FLNA FLNB TMEM94 PEX1	4.34e-05	136	16	5	HP:0002089
HumanPheno	Abnormal morphology of the chordae tendinae of the mitral valve	FLNA TMEM94	5.53e-05	4	16	2	HP:0025523
HumanPheno	Anisospondyly	HSPG2 FLNA	5.53e-05	4	16	2	HP:0002879
HumanPheno	Abnormal lung development	HSPG2 FLNA FLNB TMEM94 PEX1 CCDC40	6.06e-05	244	16	6	HP:4000059
HumanPheno	Abnormal metatarsal morphology	HSPG2 FLNA FLNB PEX1 IL2RA	9.20e-05	159	16	5	HP:0001832
HumanPheno	Aplasia/Hypoplasia of the lungs	HSPG2 FLNA FLNB TMEM94 PEX1	9.48e-05	160	16	5	HP:0006703
HumanPheno	Abnormality of the wrist	HSPG2 FLNA FLNB COL12A1 IL2RA	1.20e-04	168	16	5	HP:0003019
HumanPheno	Abnormality of the elbow	HSPG2 FLNA FLNB COL12A1 DST PEX1	1.36e-04	282	16	6	HP:0009811
HumanPheno	Spondylolysis	FLNA FLNB	1.38e-04	6	16	2	HP:0003304
HumanPheno	Abnormal mesentery morphology	WFS1 TMEM94	1.38e-04	6	16	2	HP:0100016
HumanPheno	Wrist flexion contracture	HSPG2 FLNA COL12A1	2.01e-04	38	16	3	HP:0001239
HumanPheno	Broad phalanges of the thumb	FLNA FLNB	2.56e-04	8	16	2	HP:0009651
HumanPheno	Abnormal larynx morphology	HSPG2 FLNA FLNB COL12A1 DST	2.79e-04	201	16	5	HP:0025423
HumanPheno	Joint stiffness	HSPG2 FLNA WFS1 SUMF1 IL2RA	2.85e-04	202	16	5	HP:0001387
HumanPheno	Neonatal hypotonia	FLNA COL12A1 DST SUMF1 PEX1	2.85e-04	202	16	5	HP:0001319
HumanPheno	Pectus excavatum	HSPG2 FLNA FLNB COL12A1 TMEM94 POLR2A	2.89e-04	323	16	6	HP:0000767
HumanPheno	Shoulder flexion contracture	HSPG2 COL12A1	3.29e-04	9	16	2	HP:0003044
HumanPheno	Cervical kyphosis	HSPG2 FLNB	3.29e-04	9	16	2	HP:0002947
HumanPheno	Abnormal esophagus morphology	HSPG2 FLNA DST NOP56 WFS1 TMEM94 POLR2A PEX1 PALB2 PDE11A	3.94e-04	1078	16	10	HP:0002031
HumanPheno	Fibular aplasia	FLNA FLNB	5.00e-04	11	16	2	HP:0002990
HumanPheno	Shoulder contracture	HSPG2 COL12A1	5.00e-04	11	16	2	HP:0034665
HumanPheno	Abnormality of the capitate bone	FLNA FLNB	5.99e-04	12	16	2	HP:0004262
HumanPheno	Abnormality of the hamate bone	FLNA FLNB	5.99e-04	12	16	2	HP:0004259
HumanPheno	Abnormal cervical curvature	HSPG2 FLNB	5.99e-04	12	16	2	HP:0005905
HumanPheno	Capitate-hamate fusion	FLNA FLNB	5.99e-04	12	16	2	HP:0001241
Domain	Actinin_actin-bd_CS	FLNA FLNB DST	3.08e-05	23	50	3	IPR001589
Domain	ACTININ_2	FLNA FLNB DST	3.08e-05	23	50	3	PS00020
Domain	ACTININ_1	FLNA FLNB DST	3.08e-05	23	50	3	PS00019
Domain	IG_FLMN	FLNA FLNB	3.12e-04	10	50	2	SM00557
Domain	Filamin	FLNA FLNB	3.80e-04	11	50	2	PF00630
Domain	FILAMIN_REPEAT	FLNA FLNB	3.80e-04	11	50	2	PS50194
Domain	Filamin/ABP280_rpt	FLNA FLNB	3.80e-04	11	50	2	IPR001298
Domain	Filamin/ABP280_repeat-like	FLNA FLNB	3.80e-04	11	50	2	IPR017868
Domain	DUF4599	SPATA31A7 SPATA31A5	4.56e-04	12	50	2	PF15371
Domain	DUF4599	SPATA31A7 SPATA31A5	4.56e-04	12	50	2	IPR027970
Domain	CH	FLNA FLNB DST	7.02e-04	65	50	3	SM00033
Domain	CH	FLNA FLNB DST	8.71e-04	70	50	3	PF00307
Domain	-	FLNA FLNB DST	9.08e-04	71	50	3	1.10.418.10
Domain	CH	FLNA FLNB DST	9.84e-04	73	50	3	PS50021
Domain	CH-domain	FLNA FLNB DST	1.06e-03	75	50	3	IPR001715
Pubmed	Majority of cerebrospinal fluid-contacting neurons in the spinal cord of C57Bl/6N mice is present in ectopic position unlike in other studied experimental mice strains and mammalian species.	SPATA31A1 SPATA31A7 ARMCX4 SPATA31A5	4.62e-08	24	52	4	32212159
Pubmed	The testis-specific VAD1.3/AEP1 interacts with β-actin and syntaxin 1 and directs peri-nuclear/Golgi expression with bipartite nucleus localization (BNL) sequence.	SPATA31A1 SPATA31A7 SPATA31A5	6.28e-08	6	52	3	20850414
Pubmed	Targeted disruption of the spermatid-specific gene Spata31 causes male infertility.	SPATA31A1 SPATA31A7 SPATA31A5	6.28e-08	6	52	3	25930072
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	PALS1 ABCF1 HK2 DST TUT7 PEX1 GON4L GIGYF1 QSER1	4.73e-07	650	52	9	38777146
Pubmed	Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.	FLNA FLNB ABCF1 HK2 AHNAK POLR2A NCAPH2	6.28e-07	332	52	7	32786267
Pubmed	Disruption of the Flnb gene in mice phenocopies the human disease spondylocarpotarsal synostosis syndrome.	FLNA FLNB	2.19e-06	2	52	2	17635842
Pubmed	Structural and functional aspects of filamins.	FLNA FLNB	2.19e-06	2	52	2	11336782
Pubmed	The variants at FLNA and FLNB contribute to the susceptibility of hypertension and stroke with differentially expressed mRNA.	FLNA FLNB	2.19e-06	2	52	2	33649519
Pubmed	Filamin depletion blocks endoplasmic spreading and destabilizes force-bearing adhesions.	FLNA FLNB	2.19e-06	2	52	2	21325628
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	NCOA2 FLNA FLNB SIAE NOP56 INPP5B TUT7 PEX1 QSER1 RPS6KC1	4.00e-06	1084	52	10	11544199
Pubmed	Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.	NCOA2 FLNB DST NOP56 AHNAK POLR2A GON4L PALB2	4.91e-06	645	52	8	25281560
Pubmed	Filamin-A fragment localizes to the nucleus to regulate androgen receptor and coactivator functions.	NCOA2 FLNA	6.57e-06	3	52	2	12682292
Pubmed	Filamins as integrators of cell mechanics and signalling.	FLNA FLNB	6.57e-06	3	52	2	11252955
Pubmed	Opposing FlnA and FlnB interactions regulate RhoA activation in guiding dynamic actin stress fiber formation and cell spreading.	FLNA FLNB	6.57e-06	3	52	2	28175289
Pubmed	GPIbα regulates platelet size by controlling the subcellular localization of filamin.	FLNA FLNB	6.57e-06	3	52	2	22174152
Pubmed	Filamin A and Filamin B are co-expressed within neurons during periods of neuronal migration and can physically interact.	FLNA FLNB	6.57e-06	3	52	2	12393796
Pubmed	Hexokinase 2 and nuclear factor erythroid 2-related factor 2 transcriptionally coactivate xanthine oxidoreductase expression in stressed glioma cells.	HK2 XDH	6.57e-06	3	52	2	29414774
Pubmed	Genomic structure and fine mapping of the two human filamin gene paralogues FLNB and FLNC and comparative analysis of the filamin gene family.	FLNA FLNB	6.57e-06	3	52	2	11153914
Pubmed	Sustained generation of neurons destined for neocortex with oxidative metabolic upregulation upon filamin abrogation.	FLNA FLNB	6.57e-06	3	52	2	38989458
Pubmed	Fibril treatment changes protein interactions of tau and α-synuclein in human neurons.	FLNA FLNB ABCF1 DST NOP56 AHNAK POLR2A	9.07e-06	498	52	7	36634849
Pubmed	The SH2-containing inositol polyphosphate 5-phosphatase, SHIP-2, binds filamin and regulates submembraneous actin.	FLNA FLNB	1.31e-05	4	52	2	11739414
Pubmed	Interaction of presenilins with the filamin family of actin-binding proteins.	FLNA FLNB	1.31e-05	4	52	2	9437013
Pubmed	Structural interaction and functional regulation of polycystin-2 by filamin.	FLNA FLNB	1.31e-05	4	52	2	22802962
Pubmed	Oct4 links multiple epigenetic pathways to the pluripotency network.	HSPG2 FLNA FLNB HK2 AHNAK	1.34e-05	203	52	5	22083510
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	NCOA2 FLNA PALS1 NOP56 AHNAK POLR2A QSER1	1.70e-05	549	52	7	38280479
Pubmed	Biochemical Reduction of the Topology of the Diverse WDR76 Protein Interactome.	HSPG2 FLNA FLNB NOP56 POLR2A	1.93e-05	219	52	5	31353912
Pubmed	Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis.	GRAMD1B FLNA FLNB DST INPP5B AHNAK CHML	2.11e-05	568	52	7	37774976
Pubmed	HIV infection of T cells: actin-in and actin-out.	FLNA FLNB	2.19e-05	5	52	2	19366992
Pubmed	Nephrocystin-conserved domains involved in targeting to epithelial cell-cell junctions, interaction with filamins, and establishing cell polarity.	FLNA FLNB	2.19e-05	5	52	2	12006559
Pubmed	Filamin B deficiency in mice results in skeletal malformations and impaired microvascular development.	FLNA FLNB	2.19e-05	5	52	2	17360453
Pubmed	USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.	FLNA FLNB DST AHNAK GON4L	2.65e-05	234	52	5	36243803
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	FLNA FLNB ABCF1 HK2 DST NOP56 AHNAK POLR2A TUT7 GSDMA	2.74e-05	1353	52	10	29467282
Pubmed	Sequential genome-wide CRISPR-Cas9 screens identify genes regulating cell-surface expression of tetraspanins.	ZNF438 FLNA ABCF1 TUT7 XDH LRTM2 TMEM19 PALB2	3.08e-05	832	52	8	36724073
Pubmed	Quantitative nanoproteomics for protein complexes (QNanoPX) related to estrogen transcriptional action.	FLNA FLNB AHNAK	3.23e-05	41	52	3	19805454
Pubmed	Vector-capping: a simple method for preparing a high-quality full-length cDNA library.	FLNA FLNB	3.28e-05	6	52	2	16106752
Pubmed	ASB2 targets filamins A and B to proteasomal degradation.	FLNA FLNB	3.28e-05	6	52	2	18799729
Pubmed	TRIM6 promotes colorectal cancer cells proliferation and response to thiostrepton by TIS21/FoxM1.	FLNA ABCF1 NOP56	3.73e-05	43	52	3	31992359
Pubmed	Upregulation of neurovascular communication through filamin abrogation promotes ectopic periventricular neurogenesis.	FLNA FLNB PALS1	3.73e-05	43	52	3	27664421
Pubmed	The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch.	FLNA FLNB ABCF1 AHNAK POLR2A	4.07e-05	256	52	5	33397691
Pubmed	Global proteomics of Ubqln2-based murine models of ALS.	FLNA FLNB ABCF1 DST PEX1	4.46e-05	261	52	5	33277362
Pubmed	Deltex3 inhibits Epithelial Mesenchymal Transition in Papillary Thyroid Carcinoma via promoting ubiquitination of XRCC5 to regulate the AKT signal pathway.	FLNA FLNB AHNAK	4.57e-05	46	52	3	33403043
Pubmed	The Z-disc proteins myotilin and FATZ-1 interact with each other and are connected to the sarcolemma via muscle-specific filamins.	FLNA FLNB	4.58e-05	7	52	2	16076904
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	FLNA FLNB ABCF1 DST AHNAK POLR2A TUT7	5.12e-05	653	52	7	22586326
Pubmed	Protein profile of exosomes from trabecular meshwork cells.	HSPG2 FLNA COL12A1	5.53e-05	49	52	3	21362503
Pubmed	MYH9-dependent polarization of ATG9B promotes colorectal cancer metastasis by accelerating focal adhesion assembly.	FLNA FLNB	6.10e-05	8	52	2	34131310
Pubmed	MEKK4 signaling regulates filamin expression and neuronal migration.	FLNA FLNB	6.10e-05	8	52	2	17145501
Pubmed	Filamin B mutations cause chondrocyte defects in skeletal development.	FLNA FLNB	6.10e-05	8	52	2	17510210
Pubmed	Identification of different proteins binding to Na, K-ATPase α1 in LPS-induced ARDS cell model by proteomic analysis.	FLNA FLNB NOP56 POLR2A	6.54e-05	144	52	4	35681168
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	GRAMD1B HSPG2 SIAE COL12A1 ABCF1 WFS1 SUMF1 TUT7 NCAPH2	6.54e-05	1201	52	9	35696571
Pubmed	Proteomic investigation of the interactome of FMNL1 in hematopoietic cells unveils a role in calcium-dependent membrane plasticity.	FLNB ABCF1 AHNAK	6.62e-05	52	52	3	23182705
Pubmed	Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation.	HSPG2 FLNA FLNB DST AHNAK	6.77e-05	285	52	5	21423176
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	FLNA ABCF1 DST NOP56 CAMK4 AHNAK POLR2A NEDD1	6.94e-05	934	52	8	33916271
Pubmed	Analysis of HIV-1 Gag protein interactions via biotin ligase tagging.	FLNA FLNB AHNAK	7.41e-05	54	52	3	25631074
Pubmed	Different splice variants of filamin-B affect myogenesis, subcellular distribution, and determine binding to integrin [beta] subunits.	FLNA FLNB	7.84e-05	9	52	2	11807098
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	FLNA FLNB PALS1 ABCF1 DST NOP56 AHNAK TUT7 GSDMA	9.27e-05	1257	52	9	36526897
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	HSPG2 FLNB COL12A1 HK2 DST GON4L	9.64e-05	497	52	6	23414517
Pubmed	Filamin-interacting proteins, Cfm1 and Cfm2, are essential for the formation of cartilaginous skeletal elements.	FLNA FLNB	9.79e-05	10	52	2	24436304
Pubmed	TRIM64 promotes ox-LDL-induced foam cell formation, pyroptosis, and inflammation in THP-1-derived macrophages by activating a feedback loop with NF-κB via IκBα ubiquitination.	FLNA NOP56	9.79e-05	10	52	2	36229750
Pubmed	EB1-binding-myomegalin protein complex promotes centrosomal microtubules functions.	FLNB DST AHNAK	1.17e-04	63	52	3	29162697
Pubmed	Mouse endothelial OTUD1 promotes angiotensin II-induced vascular remodeling by deubiquitinating SMAD3.	FLNA FLNB	1.20e-04	11	52	2	36579465
Pubmed	LOXL2 Upregulates Phosphorylation of Ezrin to Promote Cytoskeletal Reorganization and Tumor Cell Invasion.	FLNB ABCF1 HK2 AHNAK GSDMA	1.29e-04	327	52	5	31409639
Pubmed	SILAC-based proteomics of human primary endothelial cell morphogenesis unveils tumor angiogenic markers.	HSPG2 FLNA FLNB COL12A1	1.33e-04	173	52	4	23979707
Pubmed	Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.	FLNA FLNB ABCF1 DST NOP56 AHNAK POLR2A	1.90e-04	807	52	7	30575818
Pubmed	Faciogenital Dysplasia 5 supports cancer stem cell traits in basal-like breast cancer by enhancing EGFR stability.	FLNA FLNB DST AHNAK	1.94e-04	191	52	4	33762435
Pubmed	Cyclin D-cdk4 activity modulates the subnuclear localization and interaction of MEF2 with SRC-family coactivators during skeletal muscle differentiation.	NCOA2 CAMK4	1.97e-04	14	52	2	12130539
Pubmed	LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.	FLNA FLNB AHNAK TUT7	2.40e-04	202	52	4	33005030
Pubmed	Human transcription factor protein interaction networks.	NCOA2 HSPG2 PALS1 DST NOP56 GON4L GIGYF1 QSER1 ZBTB14	2.43e-04	1429	52	9	35140242
Pubmed	Quantitative Proteomics Links the LRRC59 Interactome to mRNA Translation on the ER Membrane.	GRAMD1B FLNA ABCF1 NOP56 WFS1	2.43e-04	375	52	5	32788342
Pubmed	Quantitative Proteomics Reveals Dynamic Interactions of the Minichromosome Maintenance Complex (MCM) in the Cellular Response to Etoposide Induced DNA Damage.	HSPG2 FLNA FLNB ABCF1 DST AHNAK GSDMA	2.50e-04	844	52	7	25963833
Pubmed	The Amot/Patj/Syx signaling complex spatially controls RhoA GTPase activity in migrating endothelial cells.	FLNA PALS1	2.60e-04	16	52	2	18824598
Pubmed	Filamin A- and formin 2-dependent endocytosis regulates proliferation via the canonical Wnt pathway.	FLNA FLNB	2.60e-04	16	52	2	27789627
Pubmed	FBW7 suppresses ovarian cancer development by targeting the N6-methyladenosine binding protein YTHDF2.	HSPG2 FLNA ABCF1 NOP56 AHNAK POLR2A	2.69e-04	601	52	6	33658012
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	GRAMD1B FLNA FLNB ABCF1 HK2 WFS1 CAMK4 RPS6KC1	2.70e-04	1139	52	8	36417873
Pubmed	Proximity labeling of endogenous RICTOR identifies mTOR complex 2 regulation by ADP ribosylation factor ARF1.	FLNA FLNB ABCF1 AHNAK	3.05e-04	215	52	4	35973513
Pubmed	Organization of focal adhesion plaques is disrupted by action of the HIV-1 protease.	FLNA FLNB	3.30e-04	18	52	2	12119179
Pubmed	Phosphopeptide binding specificities of BRCA1 COOH-terminal (BRCT) domains.	NCOA2 POLR2A	3.69e-04	19	52	2	14578343
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	FLNA FLNB DST AHNAK PALB2	4.00e-04	418	52	5	34709266
Pubmed	The catalytic subunit of the proteasome is engaged in the entire process of estrogen receptor-regulated transcription.	NCOA2 POLR2A	4.09e-04	20	52	2	16957778
Pubmed	Proteomic characterization of chromosomal common fragile site (CFS)-associated proteins uncovers ATRX as a regulator of CFS stability.	FLNA FLNB NOP56 AHNAK POLR2A GSDMA	4.15e-04	652	52	6	31180492
Pubmed	USP45 and Spindly are part of the same complex implicated in cell migration.	FLNA FLNB AHNAK TUT7	4.26e-04	235	52	4	30258100
Pubmed	ZZW-115-dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents.	FLNA FLNB ABCF1 DST NOP56 AHNAK	4.43e-04	660	52	6	32780723
Pubmed	Viral Infection-Induced Differential Expression of LncRNAs Associated with Collagen in Mouse Placentas and Amniotic Sacs.	GRAMD1B COL12A1 ABCF1	4.60e-04	100	52	3	26073538
Pubmed	Fine expression profiling of full-length transcripts using a size-unbiased cDNA library prepared with the vector-capping method.	FLNA FLNB	4.97e-04	22	52	2	18487259
Pubmed	Genome-wide association analysis identifies 11 risk variants associated with the asthma with hay fever phenotype.	GSDMA IL2RA	4.97e-04	22	52	2	24388013
Pubmed	Identification of proteins associated with ligand-activated estrogen receptor α in human breast cancer cell nuclei by tandem affinity purification and nano LC-MS/MS.	FLNA FLNB NOP56 AHNAK	4.99e-04	245	52	4	21182205
Pubmed	SLFN11 promotes CDT1 degradation by CUL4 in response to replicative DNA damage, while its absence leads to synthetic lethality with ATR/CHK1 inhibitors.	FLNA FLNB NOP56 PALB2	5.38e-04	250	52	4	33536335
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	NCOA2 PALS1 DST NOP56 QSER1 ARMCX4 SIRPG	5.52e-04	963	52	7	28671696
Pubmed	Systematic protein-protein interaction mapping for clinically relevant human GPCRs.	DST WFS1 TMEM94 QSER1 TMEM19 SLC45A4	5.90e-04	697	52	6	28298427
Pubmed	Recruitment of the Mammalian Histone-modifying EMSY Complex to Target Genes Is Regulated by ZNF131.	AHNAK POLR2A QSER1	6.08e-04	110	52	3	26841866
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	DST NOP56 AHNAK POLR2A NCAPH2 QSER1 PALB2 ZBTB14	6.31e-04	1294	52	8	30804502
Pubmed	Genetics of rheumatoid arthritis contributes to biology and drug discovery.	ZNF438 INPP5B IL2RA	6.40e-04	112	52	3	24390342
Pubmed	ATRX promotes heterochromatin formation to protect cells from G-quadruplex DNA-mediated stress.	NOP56 POLR2A	6.96e-04	26	52	2	34162889
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	ABCF1 AHNAK NCAPH2 GIGYF1 QSER1 SPAG16 NEDD1 CCDC40	7.22e-04	1321	52	8	27173435
Pubmed	Large-scale proteomics and phosphoproteomics of urinary exosomes.	HSPG2 FLNA FLNB PALS1 SIAE CAMK4 AHNAK	7.56e-04	1016	52	7	19056867
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	FLNB DST AHNAK POLR2A CHML RPS6KC1	7.83e-04	736	52	6	29676528
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	FLNA FLNB ABCF1 DST NOP56 AHNAK POLR2A	7.92e-04	1024	52	7	24711643
Pubmed	Phosphoproteomics screen reveals akt isoform-specific signals linking RNA processing to lung cancer.	WFS1 POLR2A	8.08e-04	28	52	2	24462114
Pubmed	Genetic mapping of eight SH3 domain genes on seven mouse chromosomes.	CAMK4 IL2RA	8.08e-04	28	52	2	10087302
Pubmed	Vti1b promotes TRPV1 sensitization during inflammatory pain.	FLNA FLNB DST	9.22e-04	127	52	3	30335684
Pubmed	C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.	DST WFS1 PEX1 CHML RPS6KC1	9.29e-04	504	52	5	34432599
Cytoband	Ensembl 112 genes in cytogenetic band chr9q12	SPATA31A7 SPATA31A5	3.51e-05	8	52	2	chr9q12
GeneFamily	Blood group antigens\|CD molecules\|Proteoglycans	HSPG2 SRGN	4.83e-05	7	28	2	570
ToppCell	Epithelial_cells-AT1_cells\|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id	HSPG2 FLNA COL12A1 DST WFS1 AHNAK	1.09e-07	196	52	6	6c99d29162848161c1f166a032320f87a5d5a631
ToppCell	normal_Lung-Epithelial_cells-AT1\|Epithelial_cells / Location, Cell class and cell subclass	HSPG2 FLNA COL12A1 DST WFS1 AHNAK	1.12e-07	197	52	6	7d19b93d6853828e2a036e37c4887edb1de4503c
ToppCell	Transplant_Alveoli_and_parenchyma-Epithelial-Type_1_alveolar\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	HSPG2 COL12A1 DST WFS1 AHNAK	1.21e-06	160	52	5	58ed3a074932ccc951e07868dfdc61b99ae1cc2b
ToppCell	343B-Epithelial_cells-Epithelial-I_(AT1)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	HSPG2 COL12A1 DST WFS1 AHNAK	2.41e-06	184	52	5	c7073d1b2c4fdb154d87678b92a0629c02116972
ToppCell	343B-Epithelial_cells-Epithelial-I_(AT1)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	HSPG2 COL12A1 DST WFS1 AHNAK	2.41e-06	184	52	5	1ed558a88215b248431c524ea16f13d9022ae98c
ToppCell	Control-Epithelial-ATI\|Epithelial / Disease state, Lineage and Cell class	FLNA COL12A1 DST WFS1 AHNAK	2.61e-06	187	52	5	3a032432f780525f4f4c2a358897d9989b1ecae7
ToppCell	COPD-Epithelial-ATI\|Epithelial / Disease state, Lineage and Cell class	FLNA COL12A1 DST WFS1 AHNAK	2.75e-06	189	52	5	14e8e57e4db336fbef005270647983b4edf407c0
ToppCell	AT1_cells-Donor_06\|World / lung cells shred on cell class, cell subclass, sample id	HSPG2 FLNB COL12A1 DST WFS1	3.36e-06	197	52	5	80d81be244c94c435accb643449b4ce6a3462c7f
ToppCell	356C-Epithelial_cells-Epithelial-I_(AT1)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	HSPG2 COL12A1 DST WFS1 AHNAK	3.36e-06	197	52	5	69d5b8588046d119b5dff9a7fd6f49e97e00a5b7
ToppCell	356C-Epithelial_cells-Epithelial-I_(AT1)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	HSPG2 COL12A1 DST WFS1 AHNAK	3.36e-06	197	52	5	e6cbfa267eb2e05b441fd034786faae07bb0e081
ToppCell	Epithelial_cells-AT1-AT2_cells\|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id	HSPG2 COL12A1 DST WFS1 AHNAK	3.45e-06	198	52	5	fbc46b20bcd44f2083170aacbc6f5dd00fba685c
ToppCell	(7)_Epithelial_cells-(7)_Epithelial-I_(AT1)\|(7)_Epithelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)	HSPG2 COL12A1 DST WFS1 AHNAK	3.53e-06	199	52	5	5a002d49a8b84c158f7b4d7a3e78e6a937757bb7
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Myeloid-Macrophage-macrophage,_alveolar-Macro_c2-CCL3L1\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	HK2 XDH SLC45A4 RPS6KC1	2.55e-05	146	52	4	1e81ad3d6d5d5ad2f0176d2a9593a954d38fa294
ToppCell	356C-Lymphocytic-CD4_T-cell-Treg_cell_4\|356C / Donor, Lineage, Cell class and subclass (all cells)	CAMK4 GSDMA IL2RA SIRPG	3.07e-05	153	52	4	cda759ab83a271974651fe4faa21ed4f7ecbb3ae
ToppCell	PBMC-Mild-Lymphocyte-T/NK-CD4+_T-Treg-Treg_4\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	CAMK4 GSDMA IL2RA SIRPG	3.07e-05	153	52	4	7518187a5fbf6c0881182dc79bd37c2d49f92b2e
ToppCell	PBMC-Mild-Lymphocyte-T/NK-CD4+_T-Treg-Treg_4\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CAMK4 GSDMA IL2RA SIRPG	3.07e-05	153	52	4	93d36723f01c2df39feebf20f3eba5b4fb4cdf59
ToppCell	facs-Brain_Myeloid-Cortex-24m-Myeloid-macrophage\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLNA AHNAK XDH IL2RA	3.14e-05	154	52	4	1e088b0d4a44267f46a9b643f46a1aba784686b1
ToppCell	CV-Mild-4\|CV / Virus stimulation, Condition and Cluster	HK2 WFS1 CAMK4 SIRPG	3.65e-05	160	52	4	be89efeeecb0de96ce136a7a62738f15dc0badb2
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FLNA COL12A1 HK2 WFS1	3.74e-05	161	52	4	a7e09cf2ca6cd70d40d08440fe9c5ab9befa1b79
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FLNA COL12A1 HK2 WFS1	3.74e-05	161	52	4	08920a716f6ec62538e361211455a30ad726d7be
ToppCell	E18.5-samps-Endothelial-Mature_fetal_endothelial-endothelial_cells_B\|E18.5-samps / Age Group, Lineage, Cell class and subclass	FLNB CAMK4 SRGN ARMCX4	3.93e-05	163	52	4	d6f9b7280c44d120df5a72dfc2ebb26ffbb5752b
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c04-ANXA2\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	CAMK4 SRGN AHNAK SIRPG	4.02e-05	164	52	4	8f3255d7f67890389a768453492243ea982eb38a
ToppCell	droplet-Pancreas-Exocrine-18m\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSPG2 FLNA AHNAK XDH	4.52e-05	169	52	4	53690d6f9712b54aa99a0408aae930d64ae478e5
ToppCell	droplet-Pancreas-Exocrine\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSPG2 FLNA AHNAK XDH	4.73e-05	171	52	4	92ac4cc3d54da2ea8e202aa59c78e8875356649e
ToppCell	AT1_cells-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	HSPG2 COL12A1 DST WFS1	5.65e-05	179	52	4	1603117b52623663458a977c94bf7f9f6c1114b8
ToppCell	COPD-Lymphoid-T_Regulatory\|World / Disease state, Lineage and Cell class	NCOA2 CAMK4 IL2RA SIRPG	5.77e-05	180	52	4	51a12fbad5fa7bb12e6d616a02ff9b5141e2b063
ToppCell	NS-critical-d_0-4-Epithelial-Ionocyte\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	SIAE DST WFS1 PDE11A	5.90e-05	181	52	4	cfc3ed541d93158ce26641ea30b7573d93600a11
ToppCell	5'-Adult-LargeIntestine-Hematopoietic-T_cells-Treg\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CAMK4 SRGN IL2RA SIRPG	5.90e-05	181	52	4	a6c8b33a392de3df2f179317e329e45d3d8c6f52
ToppCell	droplet-Lung-18m-Hematologic-lymphocytic-immature_innate_lymphoid_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	HK2 CAMK4 IL2RA PDE11A	5.90e-05	181	52	4	c7ad10a696d94b9ee91cd7e62761d356d5106eda
ToppCell	droplet-Lung-18m-Hematologic-lymphocytic-immature_innate_lymphoid_cell-Ly6g5b+_T\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	HK2 CAMK4 IL2RA PDE11A	5.90e-05	181	52	4	eaa3a2c268cce527004ae656d35e037b984fb4c7
ToppCell	PND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1-AT1_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	HSPG2 PALS1 AHNAK LRTM2	6.03e-05	182	52	4	573771130247e869e4e58f22d4a1cb31989635cf
ToppCell	ASK454-Epithelial\|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq	COL12A1 DST WFS1 EFHB	6.03e-05	182	52	4	ab15316cff989b61ff397a866d7ca8b49c13e981
ToppCell	PND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	HSPG2 PALS1 AHNAK LRTM2	6.03e-05	182	52	4	6cfaa2b3b3974c13b01c943f4adb70768dcc35e4
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FLNB DST ARMCX4 SLC45A4	6.16e-05	183	52	4	3427f3cbe6ea81709750e7dd3ff378f03ae65eab
ToppCell	3'-GW_trimst-2-LargeIntestine-Hematopoietic-T_cells-Treg\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SRGN GSDMA IL2RA SIRPG	6.16e-05	183	52	4	450c30d2e389fcb17825394c27f9ccc4f33022e3
ToppCell	droplet-Limb_Muscle-nan-21m-Lymphocytic-T_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CAMK4 SRGN IL2RA CCDC40	6.16e-05	183	52	4	ac70a6ec9270b1bfe089702262d4575a6c42afb4
ToppCell	P28-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_artery\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	FLNB DST SRGN SLC45A4	6.29e-05	184	52	4	8ed22b1af04a711203293e7a8b3df6fb9222fad5
ToppCell	COPD-Lymphoid-T_Regulatory\|COPD / Disease state, Lineage and Cell class	NCOA2 CAMK4 IL2RA SIRPG	6.42e-05	185	52	4	846403edd4c8f646201d519055198fc38b7ffff9
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c07-AHNAK\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	CAMK4 SRGN AHNAK SIRPG	6.69e-05	187	52	4	e1d6c1194476cf26969e405b0951796fed519f44
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FLNB COL12A1 DST WFS1	6.69e-05	187	52	4	d4b0afd9b92c47c8aa348bbd1af7eb54c3d478f2
ToppCell	P03-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_artery\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	FLNB DST SRGN SLC45A4	6.69e-05	187	52	4	66ebe1788d51b3e17bec6cdb219f709756b4e530
ToppCell	P28-Endothelial-large_vessel_endothelial_cell\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	FLNB DST SRGN SLC45A4	6.83e-05	188	52	4	263169029293e005bcffd87db20221fdd2d3917e
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_T/NK-T_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	GRAMD1B CAMK4 IL2RA SIRPG	6.98e-05	189	52	4	b87d586a9570fa54f3e0c6bd4731c5badcaedae6
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_T/NK\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	GRAMD1B CAMK4 IL2RA SIRPG	6.98e-05	189	52	4	823d6debd09e440ddf36c54af24a5f20e222a21e
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_T/NK-T_Cell-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	GRAMD1B CAMK4 IL2RA SIRPG	6.98e-05	189	52	4	47c2b419b081d5bf75da5e3d9a0e05a70362dfe7
ToppCell	(02)_Cycling_Basal_(regeneration)-(1)_24hpi\|(02)_Cycling_Basal_(regeneration) / shred by cell type and Timepoint	FLNA HK2 NOP56 AHNAK	6.98e-05	189	52	4	311f3aed469be3c8ff913dcc5a2442daa8446d55
ToppCell	facs-Pancreas-Exocrine-3m-Endothelial\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSPG2 SRGN AHNAK XDH	7.12e-05	190	52	4	b7fc451e160e31dc898b122de844b501f587db67
ToppCell	LPS-IL1RA-Endothelial-Endothelial-Artery\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	GRAMD1B HSPG2 FLNB SLC45A4	7.12e-05	190	52	4	aed65d584ca0c25f6a8313c66b421a6618af82ea
ToppCell	10x_3'_v3-lymph_node_(10x_3'_v3)-lymphocytic-T_lymphocytic-regulatory_T_cell\|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	CAMK4 SRGN IL2RA SIRPG	7.12e-05	190	52	4	b69709323a9f1b368b5a4f87295b9f7fd9c9be8e
ToppCell	PND10\|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FLNA DST SRGN AHNAK	7.12e-05	190	52	4	d67e2814047c8df2ae4b7bc8be9539f5df6ecef2
ToppCell	facs-Pancreas-Exocrine-3m-Endothelial-endothelial_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSPG2 SRGN AHNAK XDH	7.12e-05	190	52	4	83cc851fb9f644b17a8ebf4d99a646003769a22f
ToppCell	facs-Pancreas-Exocrine-3m-Endothelial-nan\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSPG2 SRGN AHNAK XDH	7.12e-05	190	52	4	5f440d4b334d66d419c03bd828f7d93f16c1ce67
ToppCell	human_hepatoblastoma-Inflammatory_Monocytes\|World / Sample and Cell Type and Tumor Cluster (all cells)	GRAMD1B HK2 SRGN IL2RA	7.27e-05	191	52	4	3b59bfc6c106ae8a3fbcd4a74bd128c485724921
ToppCell	LAM-Epithelial-AT1\|Epithelial / Condition, Lineage and Cell class	COL12A1 DST WFS1 AHNAK	7.27e-05	191	52	4	3457e15d1e9b36a78363d46b320c4ec46b40290a
ToppCell	(0)_T_CD4\|World / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)	CAMK4 SRGN IL2RA SIRPG	7.27e-05	191	52	4	ba289658777a2669fda9da9128e87adb60fd8430
ToppCell	PND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FLNB DST ARMCX4 SLC45A4	7.27e-05	191	52	4	3307dbccadb09c62b0e1c0235ec89bb294d748c3
ToppCell	NS-control-d_0-4-Lymphoid-Treg\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CAMK4 SRGN IL2RA SIRPG	7.41e-05	192	52	4	ef252dd9df161f665f53c047c0514381f80d6683
ToppCell	normal_Pleural_Fluid-B_lymphocytes-Undetermined\|B_lymphocytes / Location, Cell class and cell subclass	CAMK4 SRGN AHNAK SIRPG	7.41e-05	192	52	4	c13a438c46ee240e5832ec76880207451155c8df
ToppCell	AT1_cells-Donor_02\|World / lung cells shred on cell class, cell subclass, sample id	HSPG2 COL12A1 DST WFS1	7.41e-05	192	52	4	0444f9e9cef7403e220e862b5a787443d3f5c9ac
ToppCell	control-Lymphoid-Treg\|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	CAMK4 SRGN IL2RA SIRPG	7.41e-05	192	52	4	9067e90b7c2d734100d6e5026d753113bf9428a3
ToppCell	P15-Endothelial-large_vessel_endothelial_cell\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	FLNB DST SRGN SLC45A4	7.56e-05	193	52	4	5f9a7cd5f8eb9ac294cdb50518fedf872f3f78f5
ToppCell	PND03-Endothelial-Endothelial_blood-vessel-Macrovascular_EC\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FLNB DST SRGN ARMCX4	7.56e-05	193	52	4	58c590dd6f21bc7ae58ae1729dd574c0f1069592
ToppCell	356C-Epithelial_cells-Epithelial-I_(AT1)\|356C / Donor, Lineage, Cell class and subclass (all cells)	HSPG2 COL12A1 DST WFS1	7.87e-05	195	52	4	07a3ef6b0f1201fe2bcb9ea426b8f7a69beb4904
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_T_CD4-Trm_Th1/Th17\|lymph-node_spleen / Manually curated celltypes from each tissue	GRAMD1B CAMK4 SRGN AHNAK	7.87e-05	195	52	4	c60982804a74dbe6607c021799ca74af2204aba8
ToppCell	AT1_cells\|World / lung cells shred on cell class, cell subclass, sample id	HSPG2 COL12A1 DST WFS1	7.87e-05	195	52	4	792d6a49b0a875a00569071183d195287a9925c5
ToppCell	356C-Epithelial_cells-Epithelial-I_(AT1)-\|356C / Donor, Lineage, Cell class and subclass (all cells)	HSPG2 COL12A1 DST WFS1	7.87e-05	195	52	4	b65511770ed67f7447847e2187555b362988af45
ToppCell	COVID_non-vent-Lymphocytic-T_cell-CD4+_Memory_T_cell\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	DST CAMK4 IL2RA SIRPG	7.87e-05	195	52	4	22191d361af136942508f1553ff41a626ed982ad
ToppCell	cellseq-Epithelial-Epithelial_Alveolar-AT1-AT1\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	COL12A1 DST WFS1 AHNAK	8.03e-05	196	52	4	6731fef8c148b6681d6ed38afdf23c8213e0bbbe
ToppCell	Tracheal-10x5prime-Immune_Lymphocytic-T-T_CD4-T_reg\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CAMK4 SRGN CDKL3 SIRPG	8.03e-05	196	52	4	c0028307cf5dddfc4b5db1445fa83b74019a20bd
ToppCell	cellseq-Epithelial-Epithelial_Alveolar-AT1\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	COL12A1 DST WFS1 AHNAK	8.03e-05	196	52	4	6856317cd0cdcb88fe54b4ae905d91e13495b1c4
ToppCell	5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	HSPG2 COL12A1 DST WFS1	8.19e-05	197	52	4	c9c968e223e7814cd8d22975d849a31b7e0af7aa
ToppCell	lymphoid-T_cell-unlabelled(multiplets)\|T_cell / Lineage, cell class and subclass	FLNA SRGN AHNAK IL2RA	8.19e-05	197	52	4	f215435aee15f0ed254104bfd55670144b6d2ac3
ToppCell	5'-Adult-LymphNode-Hematopoietic-T_cells-Treg\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CAMK4 SRGN IL2RA SIRPG	8.19e-05	197	52	4	a6eba89bb3e24ae973068f85a8bcc3094e985cb9
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_T_CD4-Teffector/EM_CD4\|lymph-node_spleen / Manually curated celltypes from each tissue	FLNA CAMK4 SRGN AHNAK	8.19e-05	197	52	4	c4603bfe9ab537ca64172f65203a5d23671f7354
ToppCell	lymphoid-T_cell-Regulatory_T_cell\|lymphoid / Lineage, cell class and subclass	FLNA SRGN AHNAK IL2RA	8.19e-05	197	52	4	73d5dcf076caae60ea32258b4e9dcac8979a661e
ToppCell	5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte-AT1-AT1_L.0.5.0.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	HSPG2 COL12A1 DST WFS1	8.19e-05	197	52	4	734b8db5bb4917c9ce92ed342fe6c22b64b0d3c5
ToppCell	T_cells-CCR7+_T_cells\|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	CAMK4 SRGN IL2RA SIRPG	8.19e-05	197	52	4	904430779c42b51d3eec62cf0cdd501b17058d8b
ToppCell	ASK440-Epithelial-Type_1\|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq	COL12A1 DST WFS1 AHNAK	8.19e-05	197	52	4	782449c522c9e16e72bf999a73090688a3aefe06
ToppCell	5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte-AT1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	HSPG2 COL12A1 DST WFS1	8.19e-05	197	52	4	e344455e62b3fe94bb242dc0db58d19a1d3878c7
ToppCell	H1299-infected-SARSCoV2\|infected / Cell line, Condition and Strain	NOP56 AHNAK POLR2A TUT7	8.19e-05	197	52	4	0fa3e4cf93e77d78b1f97b906c5b13ca741ae17e
ToppCell	(2)_Fibroblasts-(24)_Fibro-5\|(2)_Fibroblasts / Cell class and subclass of bone marrow stroma cells in homeostatis	HSPG2 COL12A1 CAMK4 AHNAK	8.19e-05	197	52	4	83a4b79fbfa1cf63441dee4424c3b87c988287bf
ToppCell	Biopsy_IPF-Epithelial-AT1\|Biopsy_IPF / Sample group, Lineage and Cell type	HSPG2 COL12A1 DST WFS1	8.35e-05	198	52	4	75bdecbe111fededf6082b11de18b84ca308ef6d
ToppCell	lymphoid-T_cell-Regulatory_T_cell\|T_cell / Lineage, cell class and subclass	FLNA SRGN AHNAK IL2RA	8.35e-05	198	52	4	6773c6043ef4a3d9e9700330b6386431ee66abdc
ToppCell	ASK428-Epithelial-Type_1\|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq	COL12A1 DST WFS1 AHNAK	8.35e-05	198	52	4	0047a9ef7684230ac5179efea94461480e90bdaf
ToppCell	CTRL-Myeloid\|CTRL / Disease state, Lineage and Cell class	ZNF438 FLNA DST SRGN	8.51e-05	199	52	4	70b89a930709fdb91fde6f96106add8455b11618
ToppCell	Tracheal-NucSeq-Immune_Lymphocytic-T-T_CD4-CD4_naive/CM\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CAMK4 SRGN IL2RA SIRPG	8.51e-05	199	52	4	6150b272313d3fbf5ddcb3a8d51862d368220fe2
ToppCell	Parenchymal-NucSeq-Immune_Lymphocytic-T-T_CD8-CD8\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	GRAMD1B CAMK4 SRGN SIRPG	8.51e-05	199	52	4	0d6463e368fd611a17327322413fad145f3c7f32
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-Mono-Mono_anti-infl-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SRGN AHNAK GSDMA IL2RA	8.51e-05	199	52	4	667b8b47a5b388506e3177b46747267fad8024f6
ToppCell	Parenchymal-NucSeq-Immune_Lymphocytic-T-T_CD4-T_reg\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CAMK4 SRGN IL2RA SIRPG	8.51e-05	199	52	4	3f4907fa6d81c5691c19e6798145e9f9eccdfd20
ToppCell	Parenchymal-NucSeq-Immune_Lymphocytic-T-T_CD8-MAIT\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	GRAMD1B CAMK4 SRGN SIRPG	8.51e-05	199	52	4	036776a03fdd181e51cc655ed99331eec9c63f39
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW13-Stem_cells\|GW13 / Sample Type, Dataset, Time_group, and Cell type.	NCOA2 NOP56 TUT7 NEDD1	8.68e-05	200	52	4	d933978b55fefe52cad599b36f6b47a0c7f71f96
ToppCell	Tracheal-NucSeq-Immune_Lymphocytic-T-T_CD4\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CAMK4 SRGN IL2RA SIRPG	8.68e-05	200	52	4	d8459e45a8396a9ee063666a1928c649162c5727
ToppCell	Tracheal-NucSeq-Immune_Lymphocytic-T-T_CD4-T_reg\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CAMK4 SRGN IL2RA SIRPG	8.68e-05	200	52	4	68589705dbc84482b6c0a1a27dd552492c4e8c3d
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW13-Stem_cells-Neuroepithelial_cell\|GW13 / Sample Type, Dataset, Time_group, and Cell type.	NCOA2 NOP56 TUT7 NEDD1	8.68e-05	200	52	4	3d932765c31aef1f80a118d51e8e66c50a758dbb
ToppCell	Bronchial-NucSeq-Immune_Lymphocytic-T-T_CD4\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	GRAMD1B CAMK4 IL2RA SIRPG	8.68e-05	200	52	4	9de4d6ebb7e9bee5d811519eb05913ef30f70786
ToppCell	Biopsy_Control_(H.)-Epithelial-AT1\|Biopsy_Control_(H.) / Sample group, Lineage and Cell type	HSPG2 COL12A1 DST WFS1	8.68e-05	200	52	4	3a9633f5913f12b6865fc777c84f3f3ba795a78d
ToppCell	Control-B_memory-6\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	FLNA FLNB SIRPG	4.09e-04	124	52	3	3e987915026f503e8d072a837b6e7a34252e5c63
ToppCell	VE-CD4-CD4_Treg\|VE / Condition, Cell_class and T cell subcluster	INPP5B GSDMA IL2RA	4.59e-04	129	52	3	e89d414e1b23e1656747defa39f09b51944a2166
ToppCell	PBMC-Severe-Lymphocyte-T/NK-CD4+_T-Treg-Treg_0\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CAMK4 IL2RA SIRPG	4.70e-04	130	52	3	d47d4ff1263815896470d854d25306eb36919e70
ToppCell	PBMC-Severe-Lymphocyte-T/NK-CD4+_T-Treg-Treg_0\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	CAMK4 IL2RA SIRPG	4.70e-04	130	52	3	ad57b210c96caedadc1027b4d7a56b1bc389b137
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; HL60; HT_HG-U133A	NCOA2 HSPG2 CDKL3 NCAPH2 QSER1 CHML	3.88e-06	192	50	6	2450_DN
Drug	Isometheptene mucate; Down 200; 8.2uM; PC3; HT_HG-U133A	NCOA2 CABYR AHNAK CDKL3 NCAPH2 QSER1	4.37e-06	196	50	6	5082_DN
Drug	LY 294002; Up 200; 0.1uM; PC3; HT_HG-U133A	INPP5B PEX1 GON4L NCAPH2 TMEM19 ZBTB14	4.50e-06	197	50	6	1216_UP
Drug	Gallamine triethiodide [65-29-2]; Up 200; 4.4uM; PC3; HT_HG-U133A	CABYR INPP5B AHNAK CDKL3 NCAPH2 TMEM19	4.91e-06	200	50	6	5735_UP
Disease	osteochondrodysplasia (is_implicated_in)	HSPG2 FLNA FLNB	4.09e-06	19	49	3	DOID:2256 (is_implicated_in)
Disease	myofibrillar myopathy 5 (implicated_via_orthology)	FLNA FLNB	8.10e-06	3	49	2	DOID:0080096 (implicated_via_orthology)
Disease	distal muscular dystrophy 4 (implicated_via_orthology)	FLNA FLNB	8.10e-06	3	49	2	DOID:0111190 (implicated_via_orthology)
Disease	autoimmune thyroid disease	CAMK4 INPP5B GIGYF1 IL2RA	5.79e-05	126	49	4	EFO_0006812
Disease	emotional symptom measurement	IL2RA SLC45A4	9.65e-05	9	49	2	EFO_0007803
Disease	Hypermetropia, Myopia	NCOA2 GRAMD1B SUMF1 PDE11A	2.76e-04	189	49	4	HP_0000540, HP_0000545
Disease	Disproportionate short stature	HSPG2 FLNA FLNB	2.89e-04	77	49	3	C0878659
Disease	Schwartz-Jampel Syndrome, Type 1	HSPG2 FLNA	3.19e-04	16	49	2	C4551479
Disease	Spondyloepiphyseal Dysplasia	HSPG2 FLNA	3.19e-04	16	49	2	C0038015
Disease	Schwartz-Jampel Syndrome	HSPG2 FLNA	3.19e-04	16	49	2	C0036391
Disease	Melnick-Needles Syndrome	HSPG2 FLNA	3.19e-04	16	49	2	C0025237
Disease	Spondyloepiphyseal Dysplasia Tarda, X-Linked	HSPG2 FLNA	3.19e-04	16	49	2	C3541456
Disease	Van Buchem disease	HSPG2 FLNA	3.62e-04	17	49	2	C0432272
Disease	Adenocarcinoma of lung (disorder)	HK2 NOP56 CAMK4 RPS6KC1	3.82e-04	206	49	4	C0152013
Disease	Dyschondroplasias	HSPG2 FLNA	4.54e-04	19	49	2	C0013366
Disease	Osteochondrodysplasias	HSPG2 FLNA	4.54e-04	19	49	2	C0029422
Disease	Multiple Epiphyseal Dysplasia	HSPG2 FLNA	5.04e-04	20	49	2	C0026760
Disease	lymphocyte count	NCOA2 GRAMD1B FLNB CAMK4 AHNAK GIGYF1 CHML IL2RA SLC45A4	6.05e-04	1464	49	9	EFO_0004587
Disease	serum IgM measurement	GRAMD1B ABCF1	6.11e-04	22	49	2	EFO_0004993
Disease	type 1 diabetes mellitus	CAMK4 INPP5B IL2RA SIRPG	7.00e-04	242	49	4	MONDO_0005147
Disease	diabetes mellitus (implicated_via_orthology)	WFS1 IL2RA	8.56e-04	26	49	2	DOID:9351 (implicated_via_orthology)
Disease	Hodgkins lymphoma, multiple myeloma, chronic lymphocytic leukemia	GRAMD1B NCAPH2	9.93e-04	28	49	2	EFO_0000095, EFO_0000183, EFO_0001378
Disease	sleep duration, high density lipoprotein cholesterol measurement	ZNF438 TMEM94 SUMF1	1.08e-03	121	49	3	EFO_0004612, EFO_0005271
Disease	hypothyroidism	CAMK4 INPP5B GIGYF1 IL2RA	1.27e-03	284	49	4	EFO_0004705
Disease	eating disorder	FLNB SUMF1	1.30e-03	32	49	2	EFO_0005203
Disease	internet addiction disorder	FLNB NEDD1	1.38e-03	33	49	2	EFO_0803368
Disease	cerebrospinal fluid clusterin measurement	DST NCAPH2	1.55e-03	35	49	2	EFO_0007657
Disease	interleukin 2 receptor antagonist measurement	GRAMD1B IL2RA	1.55e-03	35	49	2	EFO_0008332

Protein segments in the cluster

Peptide	Gene	Start	Entry
DPEMQNRPTQKFSGG	ABCF1	441	Q8NE71
DPGPIQSQMEKGIFN	CDKL3	481	Q8IVW4
DNMQTFPPGEKSGEE	GSDMA	226	Q96QA5
SMPGFKAEGPEVDVN	AHNAK	886	Q09666
SMPGFKAEGPEVDVN	AHNAK	1721	Q09666
SMPGFKGEGPDVDVN	AHNAK	3031	Q09666
SMPGFKGEGPEVDVN	AHNAK	3941	Q09666
SMPGFKGEGPDVDVN	AHNAK	4661	Q09666
SGENSVPQEMEGKPV	CABYR	436	O75952
TKIQGDDMPGTGVED	ARMCX4	286	Q5H9R4
PTPQNQDGDTMVEKG	GRAMD1B	31	Q3KR37
DDKQPEAPGTNNVVM	CHML	621	P26374
QPDDFKGVNVTMPAQ	HSPG2	546	P98160
PSSKQEDGFPMQELQ	QSER1	556	Q2KHR3
KPQEVPQENGMEDPS	NOP56	486	O00567
ASPQQKKGGEDEDMP	MAGEC3	366	Q8TD91
DPQGEIQGPFTTQEM	GIGYF1	481	O75420
PLNVFMGSPGKEENE	NEDD1	461	Q8NHV4
PGSLNEEPFMKTEGN	RPS6KC1	526	Q96S38
PIQDGNEDMKAIPEG	CAMK4	361	Q16566
GEDEKTHPGFQQMPE	DST	2321	Q03001
THPGFQQMPEDKEDE	DST	2326	Q03001
EFDQEIDMGSLNPGK	HK2	276	P52789
KSPFEVQVGPEAGMQ	FLNB	536	O75369
PEGAPFTEDDEKVMQ	PDE11A	346	Q9HCR9
EGGQEPVDIKIMSFP	PKD1L2	1106	Q7Z442
KTGIDNPMFDTEEGI	PALS1	96	Q8N3R9
EDGGGKENQFLMPPE	PALB2	996	Q86YC2
KPVGSNEPMEAFVGE	COL12A1	2151	Q99715
QDPMGQKGTVEPQLE	FLNA	421	P21333
MVSPPEKDDGQKGEE	CCDC40	31	Q4G0X9
EEGGKPQMNSEGEIP	GON4L	166	Q3T8J9
GEMETSQFPGEEKPQ	IL2RA	186	P01589
GPDETKNTEPQMGLV	EFHB	201	Q8N7U6
GVPMDQSSRGQDKPE	INPP5B	271	P32019
SGEDESMNQPGPIKT	PEX1	1211	O43933
PLMGDPEGEHEDQKQ	LRTM2	351	Q8N967
NEFEPGMATKSETQP	SPATA31A7	1011	Q8IWB4
PGGPFEVMAQQTLEK	SIAE	91	Q9HAT2
SPENVEFKSGPGTEM	SIRPG	126	Q9P1W8
MGTDDPQIKQDGEAP	SUMF1	101	Q8NBK3
PGTQKDTGRTEEQPM	NCAPH2	211	Q6IBW4
TEKEEMSFEPGDQPG	NCOA2	786	Q15596
DFMGQVIFEGDPKAP	SLC45A4	531	Q5BKX6
FNDGMSEVKDEQTPG	ZBTB14	241	O43829
NEFEPGMATKSETQP	SPATA31A1	1011	Q5TZJ5
NEFEPGMATKSETQP	SPATA31A5	1011	Q5VU36
GEEEPSKTQPGMESD	TMEM94	526	Q12767
EEKGPMFELLPGESN	SRGN	51	P10124
GGEEMDNKFGVEQPE	POLR2A	156	P24928
GNTKDSEFPIDMQPN	SPAG16	311	Q8N0X2
FQEVPKGQSEEDMVG	XDH	561	P47989
MIENGPGEIPVDFSK	TMEM19	151	Q96HH6
SEQFKMPEGGDRQPQ	XAGE3	96	Q8WTP9
AESFGSPPKEEMGNE	TUT7	701	Q5VYS8
MENEGPQSGTNKPRE	ZNF438	741	Q7Z4V0
GTGPTKGDMEIPFEE	WFS1	76	O76024