Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcessmucosa-associated lymphoid tissue development

IKZF1 RET

2.41e-0513122GO:0048537
GeneOntologyBiologicalProcessPeyer's patch development

IKZF1 RET

2.41e-0513122GO:0048541
Domainzf-C2H2

IKZF1 ZNF469 ZNF710 ZNF516 ZFP91

6.96e-05693135PF00096
DomainZnf_C2H2/integrase_DNA-bd

IKZF1 ZNF469 ZNF710 ZNF516 ZFP91

7.01e-05694135IPR013087
DomainZINC_FINGER_C2H2_2

IKZF1 ZNF469 ZNF710 ZNF516 ZFP91

1.18e-04775135PS50157
DomainZINC_FINGER_C2H2_1

IKZF1 ZNF469 ZNF710 ZNF516 ZFP91

1.20e-04777135PS00028
DomainZnf_C2H2-like

IKZF1 ZNF469 ZNF710 ZNF516 ZFP91

1.34e-04796135IPR015880
DomainZnf_C2H2

IKZF1 ZNF469 ZNF710 ZNF516 ZFP91

1.42e-04805135IPR007087
DomainZnF_C2H2

IKZF1 ZNF469 ZNF710 ZNF516 ZFP91

1.44e-04808135SM00355
Domain-

IKZF1 ZNF710 ZNF516 ZFP91

9.52e-046791343.30.160.60
Pubmed

Overcoming IMiD resistance in T-cell lymphomas through potent degradation of ZFP91 and IKZF1.

IKZF1 ZFP91

1.29e-07213234936696
Pubmed

LIG family receptor tyrosine kinase-associated proteins modulate growth factor signals during neural development.

ISLR2 RET

1.17e-051413219755105
Pubmed

Defining the human C2H2 zinc finger degrome targeted by thalidomide analogs through CRBN.

IKZF1 ZFP91

2.20e-051913230385546
Pubmed

Essential roles of mitochondrial biogenesis regulator Nrf1 in retinal development and homeostasis.

ISLR2 RET

1.63e-045113230333037
Pubmed

Temporal requirements for ISL1 in sympathetic neuron proliferation, differentiation, and diversification.

ISLR2 RET

3.71e-047713229445148
CytobandEnsembl 112 genes in cytogenetic band chr2q11

LONRF2 ADRA2B

8.40e-04153132chr2q11
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

IKZF1 ZNF469 ZNF710 ZNF516 ZFP91

9.61e-0571813528
ToppCell367C-Myeloid-Macrophage-SPP1+_Macrophage_2|367C / Donor, Lineage, Cell class and subclass (all cells)

ADRA2B ZNF710 RET

8.42e-06141133e409da87da5a38ba4d0ccc5e3f8bd89f480f9dab
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-Neuronal-ventral_progenitors_and_neurons_1|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

LONRF2 ISLR2 RET

1.35e-051651339795ce31689bc63f5a2d68725ef00b23a90c3846
ToppCell3'-GW_trimst-2-SmallIntestine-Neuronal-neurons_A-Branch_A4_(IN)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LONRF2 ISLR2 RET

1.78e-05181133fb4df9a128761abe5c6310a30d7b2f7f2fdef46d
ToppCell3'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_A-Branch_A4_(IN)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LONRF2 ISLR2 RET

1.81e-05182133be32b5b8153c1053cbb55f1fccfa27c3ee97c1e1
ToppCellwk_08-11-Epithelial-PNS-PCP4+_neuron|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

LONRF2 P2RX5 RET

1.87e-05184133eac2a9089913f33a961ba11519b53645790f2056
ToppCellControl-Myeloid-cDC1|World / Disease state, Lineage and Cell class

ADRA2B ZNF710 ZNF516

1.93e-051861333de803dee3ef10eb85a2b47d3f93385214e5b0ff
ToppCell5'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_A-Branch_A3_(IPAN/IN)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LONRF2 ISLR2 RET

1.93e-0518613318fd311252299d6d30ddb32002ed069056108206
ToppCell5'-GW_trimst-2-SmallIntestine-Neuronal-neurons_A-Branch_A1_(iMN)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LONRF2 ISLR2 RET

1.96e-05187133a748b3a59e398e0da019db3f16d38adb1960c29f
ToppCellnucseq-Immune-Immune_Myeloid-Myeloid_Dendritic-cDC1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ADRA2B ZNF710 ZNF516

1.99e-05188133d5ce3ffe783c322b4765b790e861727e46bc34b3
ToppCell5'-GW_trimst-2-SmallIntestine-Neuronal-neurons_A-Branch_A4_(IN)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LONRF2 ISLR2 RET

2.02e-05189133cceca3d14dd559bbb2cb4b81ea12c2b62d18ee49
ToppCell3'-GW_trimst-2-SmallIntestine-Neuronal-neurons_A|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LONRF2 ISLR2 RET

2.15e-051931338851275bcf4ecd6e87a91c8784fc5d76d246ff3b
ToppCelldistal-3-Epithelial-Ionocyte|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

LONRF2 ADRA2B RET

2.25e-051961336ed146481dd04fb271eadc47d68eb3ae38986db6
ToppCelldistal-Epithelial-Ionocyte|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

LONRF2 ADRA2B RET

2.29e-0519713311a5d2db2561d045756980ead61e1211c7dda100
ToppCelldistal-Epithelial-Ionocyte-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

LONRF2 ADRA2B RET

2.29e-051971337a2cd970fe0866057999e40d15367b2b3324ae59
ToppCell5'-GW_trimst-2-SmallIntestine-Neuronal-neurons_A|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LONRF2 ISLR2 RET

2.32e-0519813350504a3871f76d6a5b439a56450d7770f4501eb0
ToppCellTCGA-Brain-Recurrent_Tumor-Low_Grade_Glioma-Oligodendroglioma-2|TCGA-Brain / Sample_Type by Project: Shred V9

P2RX5 ZNF469

4.14e-04105132b43de6ad90c2f61ce773699ec2b29e5413d919b1
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Mucinous_Adenocarcinoma-8|TCGA-Lung / Sample_Type by Project: Shred V9

ZNF710 RET

4.96e-0411513255a56828f86c004cd11d1a426a03e86246e949a3
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Adenocarcinoma_Mixed_Subtype-8|TCGA-Lung / Sample_Type by Project: Shred V9

ZNF710 RET

7.02e-0413713205ca83c30e3dbe74c81278b3636d57da2c20b458
ToppCell367C-Myeloid-Macrophage-SPP1+_Macrophage_2|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

ADRA2B RET

7.75e-041441323ba7f8bd6d1c551048403c94693d63e60f7cbbb7
ToppCell367C-Myeloid-Macrophage-SPP1+_Macrophage_2|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

ADRA2B RET

7.75e-0414413238ff324366ad5be626e3657c1e33277fc36ddd4c
ToppCellLPS-antiTNF-Hematopoietic_Mast-Mast_cells-Mast-cells|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

IKZF1 RET

7.75e-04144132013223bb2f31eb5bebdbd0908b797d28b96c6f7b
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

LONRF2 LAMA3

8.08e-04147132989a48bda98fbff398985397a6b1189a4cbc80e7
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

LONRF2 LAMA3

8.08e-04147132f6681c849c4c06154548bd29a094f202d1c946c2
ToppCell3'_v3-blood-Lymphocytic_Invariant-Inducer-like|blood / Manually curated celltypes from each tissue

LAMA3 RET

8.30e-0414913275422e1a22736375e9ef439db0b2a5efa3f653a3
ToppCellE12.5-Hematopoietic-Erythroid|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

IKZF1 ADRA2B

8.30e-0414913208e7f76b7e4b53ff734d50dbc853ecfdeb4b371b
ToppCellE12.5-Hematopoietic-Erythroid-enucleate_erythrocyte|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

IKZF1 ADRA2B

8.30e-04149132fb75c1b91b8a0c8221fbbc350666799727b21120
ToppCellP07-Epithelial-airway_epithelial_cell-ciliated_cell_of_airway|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

LONRF2 LAMA3

8.74e-041531325501095bcf73080872ae01128f21399f9cfc5dd1
ToppCellPSB-critical-LOC-Lymphoid-NKT|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

P2RX5 IKZF1

8.74e-041531324d45aa5e3710d5badc13940f14095c1894dbab9d
ToppCellControl-Epithelial-Ionocyte|Epithelial / Disease state, Lineage and Cell class

ADRA2B RET

8.97e-041551324b9369b203a4d7071c56d3d8e6b450e9a0121c41
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Crispld2_Kcne4|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

LAMA3 RET

9.09e-04156132896e2d958be0a5c62fb6eebad2dfb7e1ce69f3ad
ToppCell3'_v3-blood-Lymphocytic_Invariant-Inducer-like-ILC3|blood / Manually curated celltypes from each tissue

ZNF469 RET

9.20e-04157132eb2520c237543ea4869d4386afc0457b111f6193
ToppCell3'-GW_trimst-2-SmallIntestine-Hematopoietic-B_cells-CLP|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

P2RX5 IKZF1

9.20e-04157132d12f343454202da86a06d0369f8ffe5662cd091b
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_ILC|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

IKZF1 ZNF710

9.20e-04157132170197b76620df31495f1247f365da382b2d8045
ToppCelldroplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMA3 ISLR2

9.20e-04157132a426c54fd1545093d41426e9620862f71bd06f6b
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_ILC-NK_cell|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

IKZF1 ZNF710

9.20e-04157132c21520301cc0d5d4b1cc4b8ec735f9adb698e768
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c01-FCGR3A|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

IKZF1 ZNF710

9.32e-041581327274f020c0ecf216da4b6689c62bc5f49c29b6f3
ToppCellPBMC-Severe-Lymphocyte-B-B_cell-B_naive-B_naive-5|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

P2RX5 ZNF469

9.32e-0415813241cf950983f47a9e55d56041b301006b42853b37
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Gpr149_Islr|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

LAMA3 RET

9.44e-04159132c64fff8d89f84d1f5a0cc432e31f56f741162505
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Granulocytic-Mast_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

IKZF1 MRPL32

9.67e-04161132c54010d88f1ecb6e0235bb66084876a4d5bf1ecd
ToppCellControl-Epithelial-Ionocyte|World / Disease state, Lineage and Cell class

ADRA2B RET

9.79e-04162132e3b9b46ce2faff7d099502df14bbf51e9f183f8c
ToppCellControl-Epithelial-Ionocyte|Control / Disease state, Lineage and Cell class

ADRA2B RET

9.91e-04163132bf09fa39bf3e6b3a776d5e79c30c96df572956a3
ToppCell3'-GW_trimst-1.5-LargeIntestine-Neuronal-neuron_precursor|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LONRF2 RET

9.91e-0416313299cf60dc87f7ce288553091bffcd85109a02bd8f
ToppCell3'-GW_trimst-1.5-LargeIntestine-Neuronal-neuron_precursor-Neuroblast|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LONRF2 RET

9.91e-04163132510c0af66e82c5a8cf8edd0547dae4018a87dbbf
ToppCellsaliva-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c09-GZMK-FOS_l|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

P2RX5 ADRA2B

9.91e-0416313213f76f2979558f5cd27fbfd1659b413b3cac18f5
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1_VIP_PCDH20|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LAMA3 ZNF469

9.91e-04163132a53294b229fc24d4a574f0c156755b4fa7c757fc
ToppCell3'-GW_trimst-1-LargeIntestine-Hematopoietic-B_cells-CLP|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

P2RX5 IKZF1

1.00e-03164132f5cacd7b2329cb0c7c1696eb4d8f89a4bbd9dda1
ToppCellMild-Myeloid-Mast-|Mild / Condition, Lineage, Cell class and cell subclass

P2RX5 RET

1.02e-0316513293d3909a0f5f43d473d5005c842d7d73e25eceed
ToppCell3'-Pediatric_IBD-SmallIntestine-Hematopoietic-Plasma_cells-IgM_plasma_cell|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

P2RX5 ZNF469

1.02e-031651326e8370b8e747d8ef44a2413a993291a3cd83a77c
ToppCellMild-Myeloid-Mast|Mild / Condition, Lineage, Cell class and cell subclass

P2RX5 RET

1.02e-031651325fa9552c37890c5cc7e672a47038aebba2413cb4
ToppCellBronchial_Biopsy-Immune-B_cells|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X

P2RX5 IKZF1

1.03e-0316613222e94546b264c87cb55928d1591bf1b5ee2a76bd
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-DC-DC1-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ZNF469 RET

1.03e-03166132c8a7d94ed762e5e045ab5f74eef691ddc5f74993
ToppCell3'-Parenchyma_lung-Epithelial-Neuro-endocrine/ionocytic-ionocyte-Ionocyte|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADRA2B RET

1.04e-0316713249d9220f22d10ff06c0512c9c40c26ad51728e4f
ToppCell3'-Parenchyma_lung-Epithelial-Neuro-endocrine/ionocytic-ionocyte-Ionocyte-Ionocyte_L.0.7.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADRA2B RET

1.04e-031671327ec032a98a13504d15c7e3a4e259278d07f40180
ToppCell3'-Parenchyma_lung-Epithelial-Neuro-endocrine/ionocytic-ionocyte|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADRA2B RET

1.04e-031671325e3588eee73693a996bb4846427cf0038ceafbca
ToppCellControl-B_cells-Activated_B_cells|Control / group, cell type (main and fine annotations)

P2RX5 IKZF1

1.05e-03168132a7159a35fe37f8c241cf8d391debe271e0698105
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LONRF2 LAMA3

1.06e-03169132a4fd646b9bf87225131fca530bd6b52df9eaf489
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LONRF2 LAMA3

1.06e-031691324b3a7b4a497178799b6b2f0b744f5fb752cee31a
ToppCell3'-Adult-SmallIntestine-Hematopoietic-B_cells-Cycling_B_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

P2RX5 IKZF1

1.06e-03169132203971cceeba150d0e8891c92662545e84c77837
ToppCellBronchial_Brush-Immune-B_cells|Bronchial_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

P2RX5 IKZF1

1.06e-03169132dc388f660f69e37e517bf3243daf071ab138ee6e
ToppCell3'-GW_trimst-1-LargeIntestine-Hematopoietic-B_cells|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

P2RX5 IKZF1

1.08e-03170132e319ab46842d028898c09d6d8f056f896edb1558
ToppCelldroplet-Fat-Gat-18m-Lymphocytic-B_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IKZF1 ADRA2B

1.08e-031701325185187ecf26b4c9eaa0c01ad52697ab8d075cc7
ToppCell3'-Airway_Nasal-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LONRF2 RET

1.08e-03170132db0ec8b7ecbb4db108fc35c564df4b740f65cc8f
ToppCell3'-Airway_Nasal-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs-Plasmacytoid_DCs_L.1.5.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LONRF2 RET

1.08e-0317013288f6804e973863245ca1c7e5e6656d4a8b824da9
ToppCelldroplet-Liver-LIVER-NPC-1m-Lymphocytic-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IKZF1 RET

1.08e-03170132bcbe5c44ef708c5f01dc7dd9aec7b436e1a62d56
ToppCell3'-Airway_Nasal-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LONRF2 RET

1.08e-03170132dad3aaf7d9f7bafdbddee51610f03f2359e587ae
ToppCell368C-Lymphocytic-ILC-ILC-2|368C / Donor, Lineage, Cell class and subclass (all cells)

P2RX5 IKZF1

1.09e-03171132fd01076574dcc82bfd4a1538812500543b16794f
ToppCell368C-Lymphocytic-ILC|368C / Donor, Lineage, Cell class and subclass (all cells)

P2RX5 IKZF1

1.09e-031711323b3143e4aa6520ee9c6b6f2482206ad3d8205d14
ToppCell3'-GW_trimst-2-SmallIntestine-Hematopoietic-B_cells-Immature_B|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

P2RX5 IKZF1

1.10e-031721320bcb960c5ab0d3cbbdf6235b6f28327ea60ba3e3
ToppCellwk_08-11-Hematologic_Lymphocytic-B|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

P2RX5 IKZF1

1.10e-03172132d1ab8f493b70ec995281f9fb0991f1d3aa7b928f
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Monocytic-Monocyte-derived_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

IKZF1 ZNF710

1.10e-03172132f6b4754a7e4b3e38030316a0ae00d932bfa87e41
ToppCell15-Airway-Immune-Hematopoietic,_B_Cells|Airway / Age, Tissue, Lineage and Cell class

P2RX5 IKZF1

1.10e-0317213236f2444754f1e37683cb812380e6b05b356f9f4a
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-Classical_Dendritic_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

IKZF1 ZNF710

1.12e-0317313273f858f2c45d19b9ec8d99ac02c91551790f670c
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_ILC-NK_cell|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

IKZF1 ZNF469

1.13e-03174132b6725086fe5a2b057c7c495ec63c970ac52c2580
ToppCellBAL-Mild-Epithelial-Epithelial-AT1/AT2|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ADRA2B RET

1.13e-03174132b7f5492ce8098f7eb0aef30ee558d00738d59d0e
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_ILC|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

IKZF1 ZNF469

1.13e-03174132e70cc623a3a6aceec813ed852fec0c4240561133
ToppCellBAL-Mild-Epithelial-Epithelial-AT1/AT2-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ADRA2B RET

1.13e-03174132cafe4d6b5f08d8888e9db6e196c66df991c03e7b
ToppCell5'-Adult-LymphNode-Hematopoietic-T_cells-gdT|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

P2RX5 IKZF1

1.13e-03174132ccc79febfcf588d8294ffc712338be96de8a5033
ToppCellBAL-Mild-Epithelial-Epithelial-AT1/AT2-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

ADRA2B RET

1.13e-0317413271730503be3d9c839c4c9e950145e2101d682a1c
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c01-FCGR3A|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

IKZF1 ZNF469

1.13e-031741329bb8159a62640756d18ecbade3bf32bcbb7dd590
ToppCellBAL-Mild-Epithelial-Epithelial-AT1/AT2|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

ADRA2B RET

1.13e-03174132ee8ac51fa0b426ad7b7453371bb79c8bf8c1d358
ToppCellIPF-Myeloid-pDC|World / Disease state, Lineage and Cell class

IKZF1 RET

1.14e-03175132a06785a4ded01adfd29ca4c20f7759eccbe274cb
ToppCell11.5-Distal-Immune-Hematopoietic,_B_Cells|Distal / Age, Tissue, Lineage and Cell class

P2RX5 IKZF1

1.14e-03175132d8ca8fbe5309dab293c335b32f1b138edfdd0b07
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-CD4_rest|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

P2RX5 IKZF1

1.14e-031751328269721389a3ce98681460e6393f2cff816eaa25
ToppCell3'-GW_trimst-2-SmallIntestine-Hematopoietic-T_cells-Treg|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

P2RX5 IKZF1

1.15e-0317613288247142c6482f3b4fa845d64e6189c690a5ee52
ToppCell5'-GW_trimst-2-LargeIntestine-Neuronal-neurons_A|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LONRF2 RET

1.15e-03176132116741fef5895ca85057d2d31eca9eba5764ab44
ToppCellControl-B_cells-B_cells|Control / group, cell type (main and fine annotations)

P2RX5 IKZF1

1.15e-03176132d2c353783bd78dc24f28e00d917b88d8294fb5df
ToppCell5'-GW_trimst-1.5-SmallIntestine-Hematopoietic-T_cells-NK_T_cell|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

P2RX5 IKZF1

1.15e-031761321ea45cf7b7e12206c3eca1594173368643c50e59
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Monocytic|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

IKZF1 ZNF710

1.15e-03176132926ed37e636fe4dd3a18731cea15761f0c2c285a
ToppCellwk_08-11-Hematologic_Lymphocytic-B-Large_pre-B|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

P2RX5 IKZF1

1.15e-0317613278417a5ac2e45e97e7b4c56c78c25879a1b58f97
ToppCell5'-GW_trimst-2-LargeIntestine-Neuronal-neurons_A-Branch_A1_(iMN)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LONRF2 RET

1.15e-031761325b707f58d164ee7a6a527dd5d053472ce9a631c1
ToppCellControl-B_cells|Control / group, cell type (main and fine annotations)

P2RX5 IKZF1

1.15e-031761329125caa27bf790f6b1b960a86c09b4bcb1b58641
ToppCell3'-GW_trimst-1-SmallIntestine-Hematopoietic-B_cells-Pre-B|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

P2RX5 IKZF1

1.17e-03177132ecd26d086c1aff3be442fcb055611a563ca034ef
ToppCell3'-GW_trimst-1-SmallIntestine-Hematopoietic-T_cells-ILC2|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

P2RX5 IKZF1

1.17e-031771329828504591599619649d41a78daf7c052729c669
ToppCellNS-moderate-d_07-13-Epithelial-Ionocyte|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ISLR2 RET

1.17e-0317713299500aed584f793aaf308f8afbf5d1c6a9b4ee55
ToppCellCOVID-19-B_cells-Activated_B_cells|COVID-19 / group, cell type (main and fine annotations)

P2RX5 IKZF1

1.17e-03177132653bb62a3744d4024ab3186ee01d410ed62832a6
ToppCell3'-Adult-SmallIntestine-Hematopoietic-B_cells|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

P2RX5 IKZF1

1.18e-03178132580fc1d45b82010c665a313b2e7a21e0116819ef
ToppCellIPF-Myeloid-pDC|IPF / Disease state, Lineage and Cell class

IKZF1 RET

1.18e-031781328d9e28492e1f157bac3308aa947fd864ca16d277
ToppCell3'-Adult-SmallIntestine-Hematopoietic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

P2RX5 IKZF1

1.18e-03178132da1695a936dbe3ca9ee3fb28ceb60511c47b35f8
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c08-IL2RB|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

P2RX5 IKZF1

1.19e-03179132db76edd368eeca05a2a5d407c3eb2f535ade0ce3
ToppCellCOPD-Myeloid-pDC|Myeloid / Disease state, Lineage and Cell class

IKZF1 RET

1.19e-0317913229b058c5e33fda9f0d738c074bdb67ff16b9b6d5
Drugretinoic acid; Up 200; 1uM; MCF7; HT_HG-U133A_EA

P2RX5 LAMA3 ZNF710 RET

1.60e-061601341049_UP
DrugLoracarbef [121961-22-6]; Up 200; 10.8uM; PC3; HT_HG-U133A

IKZF1 ADRA2B ZNF710 ZNF516

3.51e-061951345073_UP
DrugAIT-082

ADRA2B ZFP91

9.71e-0526132CID000132123
Drugretinoic acid; Up 200; 1uM; MCF7; HT_HG-U133A_EA

P2RX5 LAMA3 ZNF710

1.11e-04170133849_UP
Drugretinoic acid; Up 200; 1uM; MCF7; HT_HG-U133A

LAMA3 ZNF710 RET

1.27e-041781331636_UP
DrugICI 182,780; Down 200; 0.01uM; MCF7; HT_HG-U133A

LAMA3 ZNF516 RET

1.35e-041821331663_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

LAMA3 ZNF710 RET

1.38e-041831333510_DN
Drug2-propylpentanoic acid; Down 200; 10000uM; MCF7; HG-U133A

IKZF1 ZNF710 RET

1.49e-04188133345_DN
Drug17-AAG; Down 200; 1uM; MCF7; HT_HG-U133A_EA

P2RX5 LAMA3 RET

1.54e-041901331056_DN
DrugEpitiostanol [2363-58-8]; Up 200; 13uM; MCF7; HT_HG-U133A

ZNF710 ZNF516 RET

1.56e-041911337342_UP
Drug17-AAG; Down 200; 1uM; MCF7; HT_HG-U133A

P2RX5 LAMA3 RET

1.61e-041931336985_DN
Drugtrichostatin A; Down 200; 0.1uM; ssMCF7; HG-U133A

P2RX5 ZNF710 RET

1.61e-04193133413_DN
Drugoxaprozin; Down 200; 300uM; MCF7; HT_HG-U133A_EA

LAMA3 ZNF710 RET

1.66e-04195133863_DN
Drugcopper(II) sulfate pentahydrate; Down 200; 100uM; PC3; HG-U133A

ZC3H14 ADRA2B RET

1.74e-04198133459_DN
DrugMelatonin [73-31-4]; Down 200; 17.2uM; MCF7; HT_HG-U133A

LAMA3 IKZF1 ZNF516

1.74e-041981335393_DN
DrugEtofenamate [30544-47-9]; Up 200; 10.8uM; MCF7; HT_HG-U133A

IKZF1 ZNF710 ZNF516

1.74e-041981337327_UP
DrugDisopyramide [3737-09-5]; Up 200; 11.8uM; MCF7; HT_HG-U133A

LAMA3 ZNF710 ZNF516

1.74e-041981337035_UP
DrugCaffeic acid [3331-39-5]; Up 200; 22.2uM; PC3; HT_HG-U133A

ZNF710 ZNF516 RET

1.76e-041991336753_UP
DrugChenodiol [474-25-9]; Down 200; 10.2uM; MCF7; HT_HG-U133A

ZNF710 ZNF516 RET

1.76e-041991337433_DN
Druggenistein; Up 200; 1uM; MCF7; HG-U133A

LAMA3 ZNF516 RET

1.76e-04199133268_UP
DrugLY 300164

ADRA2B ZFP91

2.68e-0443132CID000126756
DiseaseBurkitt Lymphoma

IKZF1 RET

9.48e-0536122C0006413
DiseaseLung diseases

ADRA2B RET

4.48e-0478122C0024115
Diseasemonocyte percentage of leukocytes

IKZF1 ADRA2B ZNF516

2.82e-03731123EFO_0007989
Diseasebasophil percentage of leukocytes

IKZF1 ZNF469

4.22e-03243122EFO_0007992

Protein segments in the cluster

PeptideGeneStartEntry
YSLGAICPKHCKVPH

ADRA2B

391

P18089
AACCHLLAKHPGKPY

ISLR2

611

Q6UXK2
VAFYHKGALPCECHP

LAMA3

1256

Q16787
CLDHAPHCPLCKDKL

LONRF2

476

Q1L5Z9
LHSGEKPFKCHLCNY

IKZF1

166

Q13422
FLKSCHFGPKNHYCP

P2RX5

216

Q93086
PECGHLKQKHVLCAY

MRPL32

111

Q9BYC8
HTGEKPYKCPYCDHR

ZNF516

56

Q92618
MHLHAGSKPFKCPYC

ZNF710

566

Q8N1W2
CIHCYHKFAHKPPIS

RET

656

P07949
CHHCGKRFPKPFKLQ

ZNF469

3311

Q96JG9
HLLKKKYVCPHPSCG

ZFP91

336

Q96JP5
PACKKMECPFYHPKH

ZC3H14

686

Q6PJT7
CGPHAKAPYLCEATH

UNQ9165/PRO28630

56

Q6UXU0