Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	Unc-13	UNC13B UNC13A	1.18e-04	3	118	2	IPR027080
Domain	-	GTF2IRD2B GTF2IRD2	2.36e-04	4	118	2	3.90.1460.10
Domain	MAP7	MAP7 MAP7D1	2.36e-04	4	118	2	PF05672
Domain	GTF2I	GTF2IRD2B GTF2IRD2	2.36e-04	4	118	2	PS51139
Domain	GTF2I	GTF2IRD2B GTF2IRD2	2.36e-04	4	118	2	PF02946
Domain	MAP7_fam	MAP7 MAP7D1	2.36e-04	4	118	2	IPR008604
Domain	GTF2I	GTF2IRD2B GTF2IRD2	2.36e-04	4	118	2	IPR004212
Domain	Munc13_dom-2	UNC13B UNC13A	3.91e-04	5	118	2	IPR014772
Domain	MHD2	UNC13B UNC13A	3.91e-04	5	118	2	PS51259
Domain	Munc13_subgr_dom-2	UNC13B UNC13A	3.91e-04	5	118	2	IPR019558
Domain	Membr_traf_MHD	UNC13B UNC13A	3.91e-04	5	118	2	PF10540
Domain	DUF1041	UNC13B UNC13A	3.91e-04	5	118	2	SM01145
Domain	PAK_BD	PAK2 PAK3	5.84e-04	6	118	2	IPR033923
Domain	AT_hook	KMT2B AHDC1 PRR12	6.44e-04	27	118	3	SM00384
Domain	AT_hook_DNA-bd_motif	KMT2B AHDC1 PRR12	6.44e-04	27	118	3	IPR017956
Domain	Munc13_1	UNC13B UNC13A	8.14e-04	7	118	2	IPR014770
Domain	MHD1	UNC13B UNC13A	8.14e-04	7	118	2	PS51258
Domain	DUF1041	UNC13B UNC13A	8.14e-04	7	118	2	PF06292
Domain	CAPS_dom	UNC13B UNC13A	8.14e-04	7	118	2	IPR010439
Domain	UBA	VPS13D UBAC1 RAD23A	8.81e-04	30	118	3	SM00165
Domain	UBA	VPS13D UBAC1 RAD23A	1.51e-03	36	118	3	PF00627
Domain	UBIQUITIN_1	ELOB UBAC1 RAD23A	1.63e-03	37	118	3	PS00299
Domain	-	RBM10 TEX13A	1.72e-03	10	118	2	4.10.1060.10
Domain	STI1	UBAC1 RAD23A	1.72e-03	10	118	2	SM00727
Domain	STI1_HS-bd	UBAC1 RAD23A	1.72e-03	10	118	2	IPR006636
Domain	S_TKc	MKNK2 OBSCN PRAG1 MAP3K4 PRKD3 CDK13 PAK2 PAK3	2.02e-03	359	118	8	SM00220
Domain	-	PAK2 PAK3	2.51e-03	12	118	2	3.90.810.10
Domain	UBA	VPS13D UBAC1 RAD23A	2.70e-03	44	118	3	IPR015940
Domain	Pkinase	MKNK2 OBSCN PRAG1 MAP3K4 PRKD3 CDK13 PAK2 PAK3	2.91e-03	381	118	8	PF00069
Domain	UBA	VPS13D UBAC1 RAD23A	3.26e-03	47	118	3	PS50030
Domain	PH	OBSCN PLEKHB1 PRKD3 ARAP3 ANLN ARAP1	3.35e-03	229	118	6	PF00169
Domain	-	OBSCN PLEKHB1 PRKD3 ARAP3 ANLN NUMB TNS3 ARAP1	3.40e-03	391	118	8	2.30.29.30
Domain	PBD	PAK2 PAK3	4.48e-03	16	118	2	SM00285
Domain	UBIQUITIN_2	ELOB UBAC1 RAD23A	4.82e-03	54	118	3	PS50053
Domain	PBD	PAK2 PAK3	5.06e-03	17	118	2	PF00786
Domain	-	ESRRG RORA RERE	5.61e-03	57	118	3	3.30.50.10
Domain	C1_1	UNC13B PRKD3 UNC13A	5.61e-03	57	118	3	PF00130
Domain	PH_dom-like	OBSCN PLEKHB1 PRKD3 ARAP3 ANLN NUMB TNS3 ARAP1	5.67e-03	426	118	8	IPR011993
Domain	Znf_NHR/GATA	ESRRG RORA RERE	5.89e-03	58	118	3	IPR013088
Domain	Ubiquitin_dom	ELOB UBAC1 RAD23A	5.89e-03	58	118	3	IPR000626
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	ELOB CHERP MAP1B MAP6 RBM10 ZKSCAN8 DIDO1 APLP2 BRD3 SEC31A AHDC1 PPP1R10 LLGL1 PIN4 PAK1IP1 CDC5L DEK TNXB UNC13A	9.06e-09	1082	123	19	38697112
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	ELOB KMT2B PCNX3 DIDO1 APLP2 BRD3 MAP7 BCOR AHDC1 CASZ1 PRR12 PPP1R10 MAP7D1 SEPTIN3 ANLN CDK13 NUMB PAK1IP1 NMT1 PRRC2A CEP170B EDRF1	1.35e-08	1497	123	22	31527615
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	KMT2B RBM10 PARG DIDO1 BRD3 BCOR ANLN CDK13 CHTF18 YY1AP1 RERE PAK1IP1 NMT1 PRRC2A CCDC9 CLUH	1.61e-08	774	123	16	15302935
Pubmed	A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.	KMT2B RBM10 HSPBP1 BCOR AHDC1 MAP7D1 CLEC4F KIAA1549L RORA YY1AP1 RERE PRRC2A TP53 RAD23A	3.61e-08	608	123	14	16713569
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	KMT2B MAP1B RBM10 BEND3 DIDO1 BCOR PPP1R10 ANLN PAK2 NUMB CDC5L PRRC2A TP53	8.29e-08	549	123	13	38280479
Pubmed	Spatiotemporal-resolved protein networks profiling with photoactivation dependent proximity labeling.	CHERP MAP1B RBM10 SEC31A BCOR PIN4 PAK2 CDC5L DEK PRRC2A TP53	1.93e-07	399	123	11	35987950
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	ELOB CHERP MAP1B RBM10 PARG DIDO1 BCOR PPP1R10 PTPN12 PDLIM3 PAK2 NUMB CDC5L NMT1 PRRC2A TP53	2.09e-07	934	123	16	33916271
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	UNC13B ATG13 RBM10 BEND3 MAP3K4 MAP7D1 CACNA1H YY1AP1 RERE CLEC16A CEP170B	2.35e-07	407	123	11	12693553
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	ELOB KMT2B RBM10 BEND3 DIDO1 BCOR AHDC1 PRR12 MAP7D1 ANLN CDK13 PIN4 PAK2 DEK PRRC2A TP53 RAD23A	3.72e-07	1103	123	17	34189442
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	MAP1B PARG DIDO1 CC2D1B PRR12 MAP7D1 ARAP3 LLGL1 CDK13 CHTF18 YY1AP1 NMT1 CLEC16A	5.65e-07	650	123	13	38777146
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	ELOB CHERP KMT2B RBM10 ZKSCAN8 BEND3 DIDO1 BRD3 MAP7 BCOR AHDC1 CASZ1 PRR12 PPP1R10 MAP7D1 CDK13 CDC5L DEK	7.23e-07	1294	123	18	30804502
Pubmed	Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.	ELOB BEND3 BRD3 AHDC1 PPP1R10 PTPN12 CDK13 RTL9 CDC5L DEK CCDC9	9.48e-07	469	123	11	27634302
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	RBM10 BACH2 ESRRG ZKSCAN8 DIDO1 BRD3 ZNF710 PPP1R10 PKNOX1 RORA CDC5L DEK TP53 NOBOX	1.11e-06	808	123	14	20412781
Pubmed	A probability-based approach for high-throughput protein phosphorylation analysis and site localization.	DIDO1 MAP7 PRKD3 PPP1R10 PTPN12 ANLN CDK13 PAK2 NUMB NMT1 PRRC2A	1.87e-06	503	123	11	16964243
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	MAP1B ATG13 MAP7 PRAG1 VPS13D MAP7D1 ANLN NUMB GNAS CEP170B EDRF1 TP53 TNS3 MTSS2	2.33e-06	861	123	14	36931259
Pubmed	Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism.	ZKSCAN8 DIDO1 BRD3 SEC31A MAP7 GTF2IRD2B MAP7D1 MZF1 CDK13 CHTF18 NUMB DEK CLEC16A PRRC2A	5.30e-06	925	123	14	28986522
Pubmed	Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.	CHERP RBM10 BCOR AHDC1 CASZ1 PRR12 ANLN RERE	5.37e-06	268	123	8	33640491
Pubmed	Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.	TMEM52 CHERP PCNX3 BACH2 OBSCN PIDD1 DIDO1 CC2D1B AHDC1 SH3D21 GTF2IRD2B PTPN12 PKNOX1 GNAS DEK CEP170B	6.32e-06	1215	123	16	15146197
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	MAP6 DIDO1 SEC31A BCOR MAP7D1 SEPTIN3 PAK2 PAK3 CDC5L GOLGA8A PRRC2A UNC13A CEP170B MTSS2	8.36e-06	963	123	14	28671696
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	KMT2B ZKSCAN8 DIDO1 BRD3 BCOR CASZ1 PPP1R10 ANLN PIN4 DEK RAD23A	1.12e-05	608	123	11	36089195
Pubmed	Regulation of insulin exocytosis by Munc13-1.	UNC13B UNC13A	1.24e-05	2	123	2	12871971
Pubmed	hHR23B is required for genotoxic-specific activation of p53 and apoptosis.	TP53 RAD23A	1.24e-05	2	123	2	16924240
Pubmed	The expression of p53-induced protein with death domain (Pidd) and apoptosis in oral squamous cell carcinoma.	PIDD1 TP53	1.24e-05	2	123	2	17437012
Pubmed	Munc13-1 is essential for fusion competence of glutamatergic synaptic vesicles.	UNC13B UNC13A	1.24e-05	2	123	2	10440375
Pubmed	Obscurin interacts with a novel isoform of MyBP-C slow at the periphery of the sarcomeric M-band and regulates thick filament assembly.	OBSCN MYBPC3	1.24e-05	2	123	2	19403693
Pubmed	RBM10, a New Regulator of p53.	RBM10 TP53	1.24e-05	2	123	2	32947864
Pubmed	A novel type of myosin encoded by the mouse deafness gene shaker-2.	LLGL1 MYO15A	1.24e-05	2	123	2	9703981
Pubmed	LncRNA CAIF inhibits autophagy and attenuates myocardial infarction by blocking p53-mediated myocardin transcription.	MYOCD TP53	1.24e-05	2	123	2	29295976
Pubmed	Differential control of vesicle priming and short-term plasticity by Munc13 isoforms.	UNC13B UNC13A	1.24e-05	2	123	2	11832228
Pubmed	Munc13 controls the location and efficiency of dense-core vesicle release in neurons.	UNC13B UNC13A	1.24e-05	2	123	2	23229896
Pubmed	Replication Stress Response Modifies Sarcomeric Cardiomyopathy Remodeling.	TP53 MYBPC3	1.24e-05	2	123	2	34323119
Pubmed	Apoptosis inhibition by the human DEK oncoprotein involves interference with p53 functions.	DEK TP53	1.24e-05	2	123	2	16894028
Pubmed	Clinical relevance of BCOR internal tandem duplication and TP53 aberration in clear cell sarcoma of the kidney.	BCOR TP53	1.24e-05	2	123	2	36563883
Pubmed	A fluorescent nanosensor paint detects dopamine release at axonal varicosities with high spatiotemporal resolution.	UNC13B UNC13A	1.24e-05	2	123	2	35613050
Pubmed	Phorbol esters modulate spontaneous and Ca2+-evoked transmitter release via acting on both Munc13 and protein kinase C.	UNC13B UNC13A	1.24e-05	2	123	2	18701688
Pubmed	Numb-dependent integration of pre-TCR and p53 function in T-cell precursor development.	NUMB TP53	1.24e-05	2	123	2	25321479
Pubmed	Comparison of TFII-I gene family members deleted in Williams-Beuren syndrome.	GTF2IRD2B GTF2IRD2	1.24e-05	2	123	2	15388857
Pubmed	Beta phorbol ester- and diacylglycerol-induced augmentation of transmitter release is mediated by Munc13s and not by PKCs.	UNC13B UNC13A	1.24e-05	2	123	2	11792326
Pubmed	p53 and p21 genetic polymorphisms and susceptibility to endometrial cancer.	PAK3 TP53	1.24e-05	2	123	2	15099969
Pubmed	Map7/7D1 and Dvl form a feedback loop that facilitates microtubule remodeling and Wnt5a signaling.	MAP7 MAP7D1	1.24e-05	2	123	2	29880710
Pubmed	Formation of perineuronal nets in organotypic mouse brain slice cultures is independent of neuronal glutamatergic activity.	UNC13B UNC13A	1.24e-05	2	123	2	17561838
Pubmed	Microtubule-associated protein 1B light chain (MAP1B-LC1) negatively regulates the activity of tumor suppressor p53 in neuroblastoma cells.	MAP1B TP53	1.24e-05	2	123	2	18656471
Pubmed	Heterodimerization of Munc13 C2A domain with RIM regulates synaptic vesicle docking and priming.	UNC13B UNC13A	1.24e-05	2	123	2	28489077
Pubmed	Regulation of p53 stability and apoptosis by a ROR agonist.	RORA TP53	1.24e-05	2	123	2	22509368
Pubmed	Progress in the research of p53 tumour suppressor activity controlled by Numb in triple-negative breast cancer.	NUMB TP53	1.24e-05	2	123	2	32501652
Pubmed	E258K HCM-causing mutation in cardiac MyBP-C reduces contractile force and accelerates twitch kinetics by disrupting the cMyBP-C and myosin S2 interaction.	TP53 MYBPC3	1.24e-05	2	123	2	23980194
Pubmed	Inhibition of exocytosis or endocytosis blocks activity-dependent redistribution of synapsin.	UNC13B UNC13A	1.24e-05	2	123	2	22066784
Pubmed	Ultrastructural Correlates of Presynaptic Functional Heterogeneity in Hippocampal Synapses.	UNC13B UNC13A	1.24e-05	2	123	2	32187536
Pubmed	Role of mammalian homologue of Caenorhabditis elegans unc-13-1 (Munc13-1) in the recruitment of newcomer insulin granules in both first and second phases of glucose-stimulated insulin secretion in mouse islets.	UNC13B UNC13A	1.24e-05	2	123	2	22814762
Pubmed	Formation and Maintenance of Functional Spines in the Absence of Presynaptic Glutamate Release.	UNC13B UNC13A	1.24e-05	2	123	2	28426965
Pubmed	Dynamic control of synaptic vesicle replenishment and short-term plasticity by Ca(2+)-calmodulin-Munc13-1 signaling.	UNC13B UNC13A	1.24e-05	2	123	2	23770256
Pubmed	Calcium-Independent Exo-endocytosis Coupling at Small Central Synapses.	UNC13B UNC13A	1.24e-05	2	123	2	31851910
Pubmed	Total arrest of spontaneous and evoked synaptic transmission but normal synaptogenesis in the absence of Munc13-mediated vesicle priming.	UNC13B UNC13A	1.24e-05	2	123	2	12070347
Pubmed	Variants in the BACH2 and CLEC16A gene might be associated with susceptibility to insulin-triggered type 1 diabetes.	BACH2 CLEC16A	1.24e-05	2	123	2	30970177
Pubmed	Munc13 genotype regulates secretory amyloid precursor protein processing via postsynaptic glutamate receptors.	UNC13B UNC13A	1.24e-05	2	123	2	23070049
Pubmed	Molecular Mechanisms of Synaptic Vesicle Priming by Munc13 and Munc18.	UNC13B UNC13A	1.24e-05	2	123	2	28772123
Pubmed	Insight into the role of alternative splicing within the RBM10v1 exon 10 tandem donor site.	RBM10 NUMB	1.24e-05	2	123	2	25889998
Pubmed	Munc13-1 C1 domain activation lowers the energy barrier for synaptic vesicle fusion.	UNC13B UNC13A	1.24e-05	2	123	2	17267576
Pubmed	P53 Promotes Retinoid Acid-induced Smooth Muscle Cell Differentiation by Targeting Myocardin.	MYOCD TP53	1.24e-05	2	123	2	29482449
Pubmed	Numb Promotes Autophagy through p53 Pathway in Acute Kidney Injury Induced by Cisplatin.	NUMB TP53	1.24e-05	2	123	2	35795076
Pubmed	Membrane bridging by Munc13-1 is crucial for neurotransmitter release.	UNC13B UNC13A	1.24e-05	2	123	2	30816091
Pubmed	A common molecular basis for membrane docking and functional priming of synaptic vesicles.	UNC13B UNC13A	1.24e-05	2	123	2	19558619
Pubmed	Phospho-tyrosine dependent protein-protein interaction network.	KMT2B PLEKHB1 AHDC1 ARAP3 MZF1 ANLN CHTF18 NUMB TP53	1.62e-05	410	123	9	25814554
Pubmed	Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.	MAP1B ATG13 PRAG1 DARS2 MAP3K4 PRKD3 PTPN12 ANLN CDK13 PAK3 NUMB DEK TNS3	2.15e-05	910	123	13	36736316
Pubmed	Large-scale concatenation cDNA sequencing.	ATG13 BRD3 AHDC1 VPS13D MAP7D1 UBAC1 PAK3 CACNA1H NMT1 TP53	3.59e-05	568	123	10	9110174
Pubmed	[Co-detection of P21, P53 and HSP70 and their possible role in diagnosis of polycyclic aromatic hydrocarbons (PAHs)-related lung cancer].	HSPBP1 TP53	3.71e-05	3	123	2	14761400
Pubmed	Early B Cell Progenitors Deficient for GON4L Fail To Differentiate Due to a Block in Mitotic Cell Division.	YY1AP1 TP53	3.71e-05	3	123	2	28381640
Pubmed	Altered cortical synaptic morphology and impaired memory consolidation in forebrain- specific dominant-negative PAK transgenic mice.	PAK2 PAK3	3.71e-05	3	123	2	15182717
Pubmed	p21-activated kinase 2 binds to transcription factor SOX2 and up-regulates DEK to promote the progression of lung squamous cell carcinoma.	PAK2 DEK	3.71e-05	3	123	2	35821094
Pubmed	cGAS surveillance of micronuclei links genome instability to innate immunity.	CGAS TP53	3.71e-05	3	123	2	28738408
Pubmed	Involvement of the DNA repair protein hHR23 in p53 degradation.	TP53 RAD23A	3.71e-05	3	123	2	14645509
Pubmed	Heterogeneous Presynaptic Distribution of Munc13 Isoforms at Retinal Synapses and Identification of an Unconventional Bipolar Cell Type with Dual Expression of Munc13 Isoforms: A Study Using Munc13-EXFP Knock-in Mice.	UNC13B UNC13A	3.71e-05	3	123	2	33105896
Pubmed	Cooperation of SRPK2, Numb and p53 in the malignant biology and chemosensitivity of colorectal cancer.	NUMB TP53	3.71e-05	3	123	2	31898732
Pubmed	A role for caspase 2 and PIDD in the process of p53-mediated apoptosis.	PIDD1 TP53	3.71e-05	3	123	2	18238895
Pubmed	Cooperation among Numb, MDM2 and p53 in the development and progression of pancreatic cancer.	NUMB TP53	3.71e-05	3	123	2	23881403
Pubmed	KRAS and GNAS mutations and p53 overexpression in biliary intraepithelial neoplasia and intrahepatic cholangiocarcinomas.	GNAS TP53	3.71e-05	3	123	2	23335286
Pubmed	Multisite autophosphorylation of p21-activated protein kinase gamma-PAK as a function of activation.	PAK2 PAK3	3.71e-05	3	123	2	10075701
Pubmed	The Rac GTPase effector p21-activated kinase is essential for hematopoietic stem/progenitor cell migration and engraftment.	PAK2 PAK3	3.71e-05	3	123	2	23335370
Pubmed	The Munc13 proteins differentially regulate readily releasable pool dynamics and calcium-dependent recovery at a central synapse.	UNC13B UNC13A	3.71e-05	3	123	2	23658173
Pubmed	The four mammalian splice variants encoded by the p21-activated kinase 3 gene have different biological properties.	PAK2 PAK3	3.71e-05	3	123	2	18507705
Pubmed	Isolation and characterisation of GTF2IRD2, a novel fusion gene and member of the TFII-I family of transcription factors, deleted in Williams-Beuren syndrome.	GTF2IRD2B GTF2IRD2	3.71e-05	3	123	2	15100712
Pubmed	RNA-binding motif protein 10 induces apoptosis and suppresses proliferation by activating p53.	RBM10 TP53	3.71e-05	3	123	2	31591476
Pubmed	Internal deletion of BCOR reveals a tumor suppressor function for BCOR in T lymphocyte malignancies.	BCOR TP53	3.71e-05	3	123	2	28827447
Pubmed	Molecular Differences between Screen-Detected and Interval Breast Cancers Are Largely Explained by PAM50 Subtypes.	KMT2B TP53	3.71e-05	3	123	2	27587435
Pubmed	NUMB controls p53 tumour suppressor activity.	NUMB TP53	3.71e-05	3	123	2	18172499
Pubmed	Aberrant morphology and residual transmitter release at the Munc13-deficient mouse neuromuscular synapse.	UNC13B UNC13A	3.71e-05	3	123	2	15988013
Pubmed	Chronic cisplatin treatment promotes enhanced damage repair and tumor progression in a mouse model of lung cancer.	PIDD1 TP53	3.71e-05	3	123	2	20395368
Pubmed	Prognostic significance of PAK family kinases in acute myeloid leukemia.	PAK2 PAK3	3.71e-05	3	123	2	30890765
Pubmed	PIDDosome-independent tumor suppression by Caspase-2.	PIDD1 TP53	3.71e-05	3	123	2	22595758
Pubmed	Amyloid Precursor-like Protein 2 Expression Increases during Pancreatic Cancer Development and Shortens the Survival of a Spontaneous Mouse Model of Pancreatic Cancer.	APLP2 TP53	3.71e-05	3	123	2	33810510
Pubmed	NUMB phosphorylation destabilizes p53 and promotes self-renewal of tumor-initiating cells by a NANOG-dependent mechanism in liver cancer.	NUMB TP53	3.71e-05	3	123	2	26174965
Pubmed	Upon intracellular processing, the C-terminal death domain-containing fragment of the p53-inducible PIDD/LRDD protein translocates to the nucleoli and interacts with nucleolin.	PIDD1 TP53	3.71e-05	3	123	2	16982033
Pubmed	Munc13- and SNAP25-dependent molecular bridges play a key role in synaptic vesicle priming.	UNC13B UNC13A	3.71e-05	3	123	2	37343100
Pubmed	Group I Paks as therapeutic targets in NF2-deficient meningioma.	PAK2 PAK3	3.71e-05	3	123	2	25596744
Pubmed	Identification of cardiac autoantigens in human heart cDNA libraries using acute rheumatic fever sera.	GNAS RAD23A	3.71e-05	3	123	2	8037842
Pubmed	A mutation spectrum that includes GNAS, KRAS and TP53 may be shared by mucinous neoplasms of the appendix.	GNAS TP53	3.71e-05	3	123	2	26160192
Pubmed	The TBC1D15 oncoprotein controls stem cell self-renewal through destabilization of the Numb-p53 complex.	NUMB TP53	3.71e-05	3	123	2	23468968
Pubmed	A post-ubiquitination role for MDM2 and hHR23A in the p53 degradation pathway.	TP53 RAD23A	3.71e-05	3	123	2	15064742
Pubmed	Interaction between Munc13-1 and RIM is critical for glucagon-like peptide-1 mediated rescue of exocytotic defects in Munc13-1 deficient pancreatic beta-cells.	UNC13B UNC13A	3.71e-05	3	123	2	17639022
Pubmed	Mutant p53 leads to low-grade IFN-I-induced inflammation and impairs cGAS-STING signalling in mice.	CGAS TP53	3.71e-05	3	123	2	37377275
Interaction	ZBTB7C interactions	BACH2 BCOR CDC5L TP53	8.32e-06	22	121	4	int:ZBTB7C
Interaction	KIF2A interactions	CGAS BRD3 MAP7 MAP7D1 ANLN CLEC16A CLUH CEP170B TP53	1.57e-05	242	121	9	int:KIF2A
Interaction	MECP2 interactions	ELOB CHERP MAP1B MAP6 RBM10 ZKSCAN8 DIDO1 APLP2 BRD3 SEC31A AHDC1 PPP1R10 LLGL1 ANLN PIN4 PAK1IP1 CDC5L DEK TNXB UNC13A TP53	2.51e-05	1287	121	21	int:MECP2
Interaction	DNAJC13 interactions	CGAS HSPBP1 MAP7 MAP3K4 NMT1 CLEC16A EDRF1	2.52e-05	143	121	7	int:DNAJC13
GeneFamily	UNC13 homologs	UNC13B UNC13A	1.01e-04	4	75	2	836
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HNBGABA	CHERP MAP1B MAP6 BACH2 NAP1L5 AHDC1 CASZ1 TBC1D24 KIAA1549L PKNOX1 PAK3 ZFHX2 GOLGA8A CNGB1 UNC13A	8.05e-07	703	120	15	M39070
Coexpression	GSE21670_UNTREATED_VS_TGFB_IL6_TREATED_CD4_TCELL_UP	BACH2 PIDD1 BRD3 CASZ1 ANLN CHTF18 DEK	3.21e-05	194	120	7	M7467
Coexpression	PEREZ_TP53_TARGETS	TMEM52 MAP6 CGAS OBSCN PIDD1 DIDO1 MAP7 BCOR AHDC1 LLGL1 PRRT3 RORA GNAS GOLGA8A CEP170B ARAP1 MTSS2	3.39e-05	1201	120	17	M4391
Coexpression	GSE22886_NAIVE_CD4_TCELL_VS_NKCELL_UP	OBSCN PIDD1 PLEKHB1 ZNF771 LIPE KCNC3 RERE	3.43e-05	196	120	7	M4423
Coexpression	GSE360_LOW_DOSE_B_MALAYI_VS_M_TUBERCULOSIS_DC_UP	SEC31A IER2 UBAC1 RERE CDC5L LYL1 TP53	3.90e-05	200	120	7	M5229
ToppCell	5'-GW_trimst-2-SmallIntestine-Mesenchymal-stromal_related\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ZFAT MAP1B FXYD7 APLP2 PDLIM3 CACNA1H MYO15A UNC80	6.29e-08	193	122	8	f27e2be497745098b5269aa799dd3d5f62d78ba7
ToppCell	5'-GW_trimst-2-SmallIntestine-Mesenchymal-stromal_related-ICC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ZFAT MAP1B FXYD7 APLP2 PDLIM3 CACNA1H MYO15A UNC80	6.29e-08	193	122	8	4ccf984baebbb13ae916727137ce593fda7514a2
ToppCell	facs-Heart-LA-24m-Endothelial-endothelial_cell_of_endocardium\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UNC13B THSD4 APLP2 CISH PDLIM3 ZFHX2 LYL1	8.57e-07	187	122	7	d9943e65eedab73d141eae524e2411653a751705
ToppCell	facs-Heart-LA-24m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UNC13B THSD4 APLP2 CISH PDLIM3 ZFHX2 LYL1	8.57e-07	187	122	7	7b13c3b67d66f3afb410141d5471c9e78a4d8623
ToppCell	LA-03._Atrial_Cardiomyocyte\|World / Chamber and Cluster_Paper	THSD4 ESRRG OBSCN CASZ1 PDLIM3 MYOCD MYBPC3	8.88e-07	188	122	7	6d249fe92d51a19da19ec14bb2262d394255d577
ToppCell	LA-03._Atrial_Cardiomyocyte\|LA / Chamber and Cluster_Paper	THSD4 ESRRG OBSCN CASZ1 PDLIM3 MYOCD MYBPC3	9.88e-07	191	122	7	5d1b674eb7703830b7ce8bbeac3363cabd0e6ae9
ToppCell	T_cells-Central_memory_CD4+_T_cells\|World / Immune cells in Kidney/Urine in Lupus Nephritis	PI16 BACH2 FXYD7 PLEKHB1 MAP3K4 RORA GOLGA8A	1.06e-06	193	122	7	725326d7e3604736b607c19f4069c81cb4f2d20c
ToppCell	COVID-19-Heart-CM_1\|Heart / Disease (COVID-19 only), tissue and cell type	THSD4 ESRRG OBSCN CASZ1 PDLIM3 MYOCD MYBPC3	1.13e-06	195	122	7	f1ef50331eda8f1239dba6ea970df4eaccf032f1
ToppCell	COVID-19-Heart-CM_2\|Heart / Disease (COVID-19 only), tissue and cell type	THSD4 ESRRG OBSCN CASZ1 PDLIM3 MYOCD MYBPC3	1.13e-06	195	122	7	75fc81bddb246dca3b437fb60827b1d4fe416405
ToppCell	LPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	THSD4 MAP1B SSPN PDLIM3 PAK3 MYOCD TNXB	1.30e-06	199	122	7	e9820d5fb4e8b46973c4c50ac5db8fb4a1bf603b
ToppCell	LPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	THSD4 MAP1B SSPN PDLIM3 PAK3 MYOCD TNXB	1.34e-06	200	122	7	08bf8c00eee6468215edb3611296bfc8784c4d56
ToppCell	PND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_prolif\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	THSD4 MAP1B SSPN CHTF18 PAK3 TNXB	6.77e-06	167	122	6	784776d1fcc098f84d3c2eca58fa56cb9428f434
ToppCell	PND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_prolif\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	THSD4 OBSCN PIDD1 PDLIM3 MYOCD MYBPC3	6.77e-06	167	122	6	91b14df450bfb6a2b406c88f8c75cd51eeb9e82b
ToppCell	Ionocyte-iono-1\|World / Class top	TMEM52 ELOB ESRRG PDLIM3 GNAS EDRF1	7.25e-06	169	122	6	4b68bcb4b5fc3cd2db23cd4edace7444aa2d605c
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_B-B_cell-B_c04-SOX5-TNFRSF1B\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	KMT2B MKNK2 PRAG1 PRKD3 SSPN GOLGA8A	8.56e-06	174	122	6	ebe6ce173ad12d4a2afa39f8d6185c0e4f97fb1e
ToppCell	droplet-Heart-nan-3m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM52 PARG SEC31A PPP1R10 SSPN MYOCD	9.13e-06	176	122	6	749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	THSD4 SSPN PDLIM3 PAK3 MYOCD TNXB	1.01e-05	179	122	6	02c90d8306016365ed811f0c63cfb3ac7b85464c
ToppCell	COVID-19-Heart-CM_3\|Heart / Disease (COVID-19 only), tissue and cell type	THSD4 ESRRG OBSCN PDLIM3 MYOCD MYBPC3	1.11e-05	182	122	6	287fcc3897ae08841f6f85ae6c9cef16f75b1dd1
ToppCell	Pericytes-Donor_03\|World / lung cells shred on cell class, cell subclass, sample id	MAP1B CCDC168 SSPN PDLIM3 MYOCD CACNA1H	1.14e-05	183	122	6	d04deef7cd4e1738227a6593b84874ce0168c773
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Neuronal-neurons_B-Branch_B2_(eMN)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MAP1B FXYD7 TMEM130 SEPTIN3 ZFHX2 CNGB1	1.21e-05	185	122	6	3d6711030ca4328357b06d5497cf98cdefcd7f4f
ToppCell	COVID-19-Heart-CM_2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	THSD4 ESRRG OBSCN PDLIM3 MYOCD MYBPC3	1.21e-05	185	122	6	549eeb521c3985bff396ea0f202db21822efa51f
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	THSD4 SSPN PDLIM3 PAK3 MYOCD TNXB	1.21e-05	185	122	6	3b2dfc8f4c87be516265dbecfc251276034d0efd
ToppCell	5'-GW_trimst-2-LargeIntestine-Neuronal-neurons_B\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MAP1B MAP6 FXYD7 SEPTIN3 CNGB1 UNC80	1.25e-05	186	122	6	15f2e5905486e33f6f7b3b3e9758a0559e8c61ee
ToppCell	Cerebellum-Neuronal\|Cerebellum / BrainAtlas - Mouse McCarroll V32	MAP1B ESRRG TMEM130 PAK3 UNC13A UNC80	1.29e-05	187	122	6	61b9d6eb131a674598aa8409d7fa909c8765442d
ToppCell	RV-04._Ventricular_Cardiomyocyte_I\|World / Chamber and Cluster_Paper	THSD4 ESRRG OBSCN CASZ1 MYOCD MYBPC3	1.29e-05	187	122	6	78cdcf8bc141d3b155c3c8af908431fc419c4d08
ToppCell	facs-Trachea-18m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	THSD4 ESRRG PLEKHB1 PDLIM3 MYOCD MTSS2	1.33e-05	188	122	6	340f0e3e65c7a00d82d26621ff37107458bebc41
ToppCell	facs-Trachea-18m-Mesenchymal-myofibroblast\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	THSD4 ESRRG PLEKHB1 PDLIM3 MYOCD MTSS2	1.33e-05	188	122	6	9d384c0934f1461bc37b1f83e0877d7bee2116ee
ToppCell	RV-04._Ventricular_Cardiomyocyte_I\|RV / Chamber and Cluster_Paper	THSD4 ESRRG OBSCN CASZ1 MYOCD MYBPC3	1.37e-05	189	122	6	9c1debd65c13d63fd4f3158917d621b44b714c26
ToppCell	RV-06._Ventricular_Cardiomyocyte_II\|World / Chamber and Cluster_Paper	THSD4 ESRRG OBSCN CASZ1 MYOCD MYBPC3	1.37e-05	189	122	6	5e80c47f63980904c4c1ff02c201b67b456a0974
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m-Epithelial\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLEKHB1 IER2 PDLIM3 CDK13 PRRC2A MTSS2	1.37e-05	189	122	6	965e0e388251e7318f8b463816dc96ccb4658677
ToppCell	RV-15._Ventricular_Cardiomyocyte_III\|World / Chamber and Cluster_Paper	THSD4 ESRRG OBSCN PDLIM3 MYOCD MYBPC3	1.37e-05	189	122	6	0a82931b5f6c0a6427ca3edd5e2235ac49099d40
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	THSD4 MAP1B SSPN PDLIM3 PAK3 MYOCD	1.37e-05	189	122	6	45e588b2a4ad9e3ff74e22d9d627ed3571f3b8b8
ToppCell	RV-15._Ventricular_Cardiomyocyte_III\|RV / Chamber and Cluster_Paper	THSD4 ESRRG OBSCN PDLIM3 MYOCD MYBPC3	1.41e-05	190	122	6	93c3188dfeb0b2f9889f8ae9b9c1f2f34129c99b
ToppCell	RV-06._Ventricular_Cardiomyocyte_II\|RV / Chamber and Cluster_Paper	THSD4 ESRRG OBSCN CASZ1 MYOCD MYBPC3	1.41e-05	190	122	6	fe8e78922c8ae928ef9a80bffd67868d5a87a091
ToppCell	10x5'v1-week_14-16-Mesenchymal_fibro-stroma-arteriolar_fibroblast\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	THSD4 PI16 SSPN TMEM130 PDLIM3 TNXB	1.45e-05	191	122	6	5271198116343c07202649889057e5774d7fdde3
ToppCell	Control-Stromal_mesenchymal\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	THSD4 SSPN PDLIM3 PAK3 MYOCD TNXB	1.45e-05	191	122	6	14057205ddb9b4bbc582d1358d13cf36d979a61b
ToppCell	COVID-19-Heart-CM_+_EC_+_Pericyte\|Heart / Disease (COVID-19 only), tissue and cell type	THSD4 ESRRG OBSCN PDLIM3 MYOCD MYBPC3	1.54e-05	193	122	6	dd5378a1ef8eb0eda9a3aae62f3c2f3a1402bda0
ToppCell	facs-Pancreas-Endocrine\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAP1B NAP1L5 PAK3 ZFHX2 GNAS UNC80	1.54e-05	193	122	6	15c86e20b97b6983410b36d308cddff56d141c98
ToppCell	RA-03._Atrial_Cardiomyocyte\|RA / Chamber and Cluster_Paper	THSD4 ESRRG OBSCN CASZ1 MYOCD MYBPC3	1.59e-05	194	122	6	c3535f7cc0076653c72db582047cff053c322397
ToppCell	frontal_cortex-Neuronal\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	MAP1B NAP1L5 TMEM130 SEPTIN3 PAK3 UNC80	1.68e-05	196	122	6	de7d10da862f98894ce47244fbc992f4a12d63bb
ToppCell	droplet-Heart-nan-18m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UNC13B THSD4 APLP2 CISH PDLIM3 ZFHX2	1.68e-05	196	122	6	e386526332138e636aef2542c11316347a45689c
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MAP1B KIAA1549L PAK3 GNAS UNC13A UNC80	1.78e-05	198	122	6	8ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCell	Frontal_cortex-Neuronal\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	MAP1B TMEM130 SEPTIN3 UNC13A CEP170B UNC80	1.83e-05	199	122	6	f88039d862f3bfa01dc39d2de4f3f548dc5a0e61
ToppCell	proximal-mesenchymal-Airway_Smooth_Muscle-3\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	THSD4 MAP1B SSPN PDLIM3 MYOCD CACNA1H	1.89e-05	200	122	6	6fa339666c4032b29ac521e88f0e917a57013cde
ToppCell	LPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	THSD4 MAP1B SSPN PDLIM3 PAK3 MYOCD	1.89e-05	200	122	6	c596a53c0b63c9deaac7d99fcbdd94ecfa96b86c
ToppCell	proximal-3-mesenchymal-Airway_Smooth_Muscle\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	THSD4 MAP1B SSPN PDLIM3 MYOCD CACNA1H	1.89e-05	200	122	6	e9a008bfe336002218c63d1c2231986e1b237621
ToppCell	LPS_only-Mesenchymal_myocytic-Myofibroblastic\|LPS_only / Treatment groups by lineage, cell group, cell type	THSD4 MAP1B SSPN PDLIM3 MYOCD TNXB	1.89e-05	200	122	6	02cae2c296a13ad4cbb53bca7a86d64629d67d66
ToppCell	proximal-mesenchymal-Airway_Smooth_Muscle\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	THSD4 MAP1B SSPN PDLIM3 MYOCD CACNA1H	1.89e-05	200	122	6	5eeb8eb3fe74f5a8055c52ec77e38237bb63ed90
ToppCell	LPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	THSD4 MAP1B SSPN PDLIM3 PAK3 MYOCD	1.89e-05	200	122	6	dcdaec3ca3a3024dc1b8788c417003f84c2bffdc
ToppCell	LV-03._Atrial_Cardiomyocyte\|LV / Chamber and Cluster_Paper	THSD4 TMEM52 CCDC168 PRRC2A MYBPC3	2.01e-05	120	122	5	3b77bd0e3630cdd45001cecf5e47660a90ebc92e
ToppCell	RV-03._Atrial_Cardiomyocyte\|World / Chamber and Cluster_Paper	THSD4 ESRRG OBSCN MYOCD MYBPC3	2.17e-05	122	122	5	1cb1dd03b2aaedbe04f3ed907568c3b7f54767b3
ToppCell	E18.5-samps-Mesenchymal-Matrix_fibroblast-matrix_-_immature_4\|E18.5-samps / Age Group, Lineage, Cell class and subclass	GGN PIDD1 ANLN PRRT3 TNXB	2.95e-05	130	122	5	169d88bffd7cd813a484d809defa638ceaca4bcb
ToppCell	Mild/Remission-B_naive-4\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	BACH2 APLP2 CACNA1H RERE SPAG17	5.48e-05	148	122	5	dd5e1bc02824e743e1c030a303e32f27a359a8ca
ToppCell	TCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Lobular_Carcinoma\|TCGA-Breast / Sample_Type by Project: Shred V9	PRAG1 SH3D21 YJU2B MZF1 LYL1	6.82e-05	155	122	5	a4f2fffa8d0de760c556c3f8f1c91804eedbfa68
ToppCell	lymphoid-T_cell-pro-T_cell\|World / Lineage, cell class and subclass	OBSCN CASZ1 MYO15A MTSS2	6.94e-05	80	122	4	9bd3ad5029eb84efcdbf08fe268c29fa9b0b302b
ToppCell	Children_(3_yrs)-Mesenchymal-vascular_smooth_muscle_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	MAP1B SAMD15 PDLIM3 MYOCD CACNA1H	7.46e-05	158	122	5	84c0a215dabf697ada036c2b9592d0c61b5077de
ToppCell	Ciliated_cells-A-HP_01\|World / lung cells shred on cell class, cell subclass, sample id	MARCHF10 MAP1B MAP6 ESRRG SPAG17	7.69e-05	159	122	5	0c65ae6140abd48c79b04758a6217709ddd15385
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-stromal_related-ICC\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ZFAT FXYD7 APLP2 SPAG17 UNC80	9.16e-05	165	122	5	b1bbf5acdfc52bd8c7c7eb356d73b812eb6b908c
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-stromal_related\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ZFAT FXYD7 APLP2 SPAG17 UNC80	9.16e-05	165	122	5	28f8297ec7b781149cc7ac2f5e441771083b8ee3
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal-Granular_Neuron_CB_Gabra6\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ESRRG SEPTIN3 GTF2IRD2 UNC13A UNC80	9.42e-05	166	122	5	ec7bd549bda5f18aca8aebce5ba479a81abbbeda
ToppCell	PND01-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_mature\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	OBSCN PDLIM3 ZFHX2 MYOCD MYBPC3	9.42e-05	166	122	5	390cf5e56b72fcaf3b8520930bd35a3e3e173711
ToppCell	PND01-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	OBSCN PDLIM3 ZFHX2 MYOCD MYBPC3	9.42e-05	166	122	5	9a341dc7b756252caeaac1e934384911c880a634
ToppCell	356C-Myeloid-Macrophage-SPP1+_Macrophage_4\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	ZFAT BEND3 MAP7 SSPN PDLIM3	9.42e-05	166	122	5	8d5d09f25e8903d481c2097fed435e69d42ccdb5
ToppCell	tumor_Lymph_Node_/_Brain-Myeloid_cells-Pleural_Mac\|Myeloid_cells / Location, Cell class and cell subclass	OBSCN PIDD1 PLEKHB1 LLGL1 CLUH	9.96e-05	168	122	5	8697b40b2ec2cce68ef3beb4792eb3eff29be053
ToppCell	facs-Heart-RA-18m-Endothelial-endothelial_cell_of_endocardium\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UNC13B THSD4 ARAP3 KIAA1549L ZFHX2	9.96e-05	168	122	5	06dc5b2d356d3a9454b10bba6f3b9ead2a0a7d46
ToppCell	control-Myeloid-pDC\|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	ZFAT ZFYVE27 CCDC168 CASZ1 CHTF18	9.96e-05	168	122	5	affc39c7568b7df4b36af6f5b0e3702a18b6268c
ToppCell	facs-Heart-RA-18m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UNC13B THSD4 ARAP3 KIAA1549L ZFHX2	9.96e-05	168	122	5	1002f058a340763e3d8de0bd1f0547a903526ec6
ToppCell	Ionocyte\|World / Class top	TMEM52 ELOB ESRRG PDLIM3 GNAS	1.05e-04	170	122	5	d2e592f2a679e6a8d32f2b752d9a3c493e50ced4
ToppCell	E16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_prolif\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MAP1B FXYD7 PDLIM3 MYOCD CLEC16A	1.17e-04	174	122	5	c529f3674b784f872f4387ffdeb46aecb619976b
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Neuronal-neurons_B-Branch_B1_(eMN)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SEPTIN3 ZFHX2 MYO15A CNGB1 UNC80	1.17e-04	174	122	5	271c51d220842402975d97c86c9acfdbdf62a32c
ToppCell	facs-Heart-RA-24m-Endothelial-endothelial_cell_of_endocardium\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THSD4 CAMP APLP2 CISH ZFHX2	1.17e-04	174	122	5	42dfb6f42b72e40e203b3ef341117bccf3553d54
ToppCell	facs-Heart-RA-24m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THSD4 CAMP APLP2 CISH ZFHX2	1.17e-04	174	122	5	f04edf2ca6788875c9918611e416fb739924382e
ToppCell	PBMC-Convalescent-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-14\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	PIDD1 AHDC1 SSPN MANBAL CCDC9	1.21e-04	175	122	5	87e557f7508c88b2087db5d57e77d5e2c92ca083
ToppCell	3'-Parenchyma_lung-Epithelial-Epithelial_transtional-epithelial_cell_of_lung-Transitional_Club-AT2-Transitional_Club-AT2_L.0.4.1.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	BEND3 MAP7 CASZ1 TMEM130 GOLGA8A	1.21e-04	175	122	5	dbd9dac129fb6ae5f55e7b96d04b37585458dc4a
ToppCell	facs-Heart-RV-18m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NAP1L5 AHDC1 CACNA1H UNC13A CEP170B	1.27e-04	177	122	5	7c3d46ebd7e8726be6871aa9763e281fc0ec6ac8
ToppCell	facs-Heart-RV-18m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NAP1L5 AHDC1 CACNA1H UNC13A CEP170B	1.27e-04	177	122	5	e7b1f3092e6b8d0d580f82648035f5ad12be6961
ToppCell	URO-Lymphocyte-T_NK-CD4_TCM\|URO / Disease, Lineage and Cell Type	PI16 FXYD7 PLEKHB1 CISH RORA	1.34e-04	179	122	5	cdf972acf23c7a22c99a336ee0f9cc51e0fa6f67
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_B-B_atypical-male\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	DIDO1 AHDC1 SH3D21 LLGL1 CLEC16A	1.34e-04	179	122	5	5be883d7d0be3180bb9844e4a757f0dd247294e4
ToppCell	facs-Heart-RA-24m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THSD4 CAMP CISH ARAP3 CNGB1	1.38e-04	180	122	5	174c643e046646e3b305dd7e5b120d2c9a46690f
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_B-Branch_B1_(eMN)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MAP1B MAP6 FXYD7 SEPTIN3 CNGB1	1.41e-04	181	122	5	7f99002a6411117cc2361334c7c9228e20c574b4
ToppCell	Globus_pallidus-Neuronal-Inhibitory\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	MAP1B ESRRG NAP1L5 TMEM130 CEP170B	1.45e-04	182	122	5	04ccfa951eaa31fed6d140edb6c702d49363c5fa
ToppCell	5'-GW_trimst-2-LargeIntestine-Neuronal-neurons_B-Branch_B1_(eMN)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MAP1B MAP6 FXYD7 CNGB1 UNC80	1.49e-04	183	122	5	7e2bac8b005155888ff4b41ef2e1d975dc17abc7
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	THSD4 PDLIM3 PAK3 MYOCD TNXB	1.49e-04	183	122	5	7eae9b3b4d1c9b135fa7cff348393d4adec474b4
ToppCell	3'-GW_trimst-2-SmallIntestine-Mesenchymal-stromal_related-ICC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ZFAT FXYD7 APLP2 MYO15A UNC80	1.49e-04	183	122	5	262387ee8d43b96e5f1a77c75124459a506a6172
ToppCell	3'-GW_trimst-2-SmallIntestine-Mesenchymal-stromal_related\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ZFAT FXYD7 APLP2 MYO15A UNC80	1.49e-04	183	122	5	c85a707acbcb582912e8ac080a36d05f91cfd7a2
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OBSCN MYOCD MYO15A SPAG17 UNC80	1.53e-04	184	122	5	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Large_Intestine-Distal-3m-Epithelial-enteroendocrine_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAP1B NAP1L5 TMEM130 UNC13A UNC80	1.53e-04	184	122	5	3da93e7d8b62463e307cc0425c47dbd3bef66799
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OBSCN MYOCD MYO15A SPAG17 UNC80	1.53e-04	184	122	5	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OBSCN MYOCD MYO15A SPAG17 UNC80	1.53e-04	184	122	5	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	LV-15._Ventricular_Cardiomyocyte_III\|LV / Chamber and Cluster_Paper	THSD4 ESRRG OBSCN MYOCD MYBPC3	1.53e-04	184	122	5	ab7a1620c14a9d9b6be1b47c559931e345e9eef8
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ESRRG TMEM130 SEPTIN3 KCNC3 UNC80	1.53e-04	184	122	5	7d9bcdaff8cbea4c50ab7db0f8e01f6bbd0ef593
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_Arw_fibro_(16)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	PI16 TMEM130 PDLIM3 PAK3 UNC80	1.56e-04	185	122	5	7dcdc009c5681ee05dd18968f7e85c3403fe34af
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	THSD4 PDLIM3 PAK3 MYOCD TNXB	1.56e-04	185	122	5	6712512100ccef456d2e2bd201d0987986c92ac9
ToppCell	droplet-Limb_Muscle-Pre-Sort-18m-Macroglial-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AMBN PLEKHB1 SEPTIN3 KIAA1549L UNC80	1.56e-04	185	122	5	11c147f3f5570c4761d2bcff3bad28146b4a5861
ToppCell	Adult-Epithelial-ciliated_cell-D175\|Adult / Lineage, Cell type, age group and donor	MARCHF10 MAP6 ESRRG ZFHX2 SPAG17	1.56e-04	185	122	5	30f4980dee6cd5959655f8d74049f3bfb5312611
ToppCell	LV-15._Ventricular_Cardiomyocyte_III\|World / Chamber and Cluster_Paper	THSD4 ESRRG OBSCN MYOCD MYBPC3	1.56e-04	185	122	5	6baccb26f999145e51b91d94315bf8d4655bef31
ToppCell	droplet-Heart-nan-18m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UNC13B APLP2 PRAG1 LIPE ARAP3	1.56e-04	185	122	5	a32d5cb596ebac80eb1ac301055e65d420879ec8
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	THSD4 MAP1B PDLIM3 PAK3 MYOCD	1.60e-04	186	122	5	6add08d4ca019ff2864acdd5ec2c66a59a574591
ToppCell	390C-Lymphocytic-CD4_T-cell-Treg_cell_1\|390C / Donor, Lineage, Cell class and subclass (all cells)	VPS13D MZF1 CDK13 CHTF18 CCDC9	1.60e-04	186	122	5	064b6047215597465bb51a8a1547ef5a226552f9
ToppCell	facs-Brain_Non-Myeloid-Striatum_-18m-Neuronal-interneuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PI16 SLC2A7 SEPTIN3 KCNC3 MTSS2	1.60e-04	186	122	5	a1ab273b01971d6a892912560d387685dd657179
Drug	Nomifensine maleate [32795-47-4]; Up 200; 11.2uM; MCF7; HT_HG-U133A	TEX13A LLGL1 CACNA1H GNAS MYO15A LYL1 NMT1 MTSS2	1.13e-05	197	122	8	7217_UP
Drug	Pentolinium bitartrate [52-62-0]; Down 200; 7.4uM; MCF7; HT_HG-U133A	BCOR AHDC1 SSPN CDK13 PKNOX1 CDC5L EDRF1 GPRIN2	1.17e-05	198	122	8	2305_DN
Drug	Levonordefrin [829-74-3]; Down 200; 21.8uM; MCF7; HT_HG-U133A	KMT2B PIDD1 ZNF710 MZF1 PKNOX1 CLEC16A PRRC2A ARAP1	1.17e-05	198	122	8	3450_DN
Drug	Sulfamethoxazole [723-46-6]; Up 200; 15.8uM; PC3; HT_HG-U133A	PLEKHB1 DARS2 CISH PTPN12 PIN4 LYL1 CCDC9 EDRF1	1.22e-05	199	122	8	7366_UP
Drug	nordihydroguaiaretic acid; Down 200; 1uM; MCF7; HT_HG-U133A	MAP3K4 ZNF710 SSPN MAP7D1 MZF1 PKNOX1 CEP170B ARAP1	1.22e-05	199	122	8	1648_DN
Drug	Coralyne chloride hydrate [38989-38-7]; Down 200; 9.6uM; MCF7; HT_HG-U133A	MAP7 BCOR PLEKHB1 CISH MZF1 PKNOX1 CLEC16A ARAP1	1.26e-05	200	122	8	2652_DN
Drug	LY 294002; Up 200; 10uM; PC3; HT_HG-U133A	UNC13B BACH2 DIDO1 MAP7 ZFHX2 CEP170B MYBPC3	5.55e-05	181	122	7	1236_UP
Drug	Prochlorperazine dimaleate [84-02-6]; Down 200; 6.6uM; HL60; HT_HG-U133A	PIDD1 HSPBP1 PKNOX1 CDC5L NMT1 PRRC2A CEP170B	8.04e-05	192	122	7	1286_DN
Drug	Guanabenz acetate [23256-50-0]; Down 200; 13.8uM; PC3; HG-U133A	HSPBP1 MAP7 CASZ1 CISH PAK3 CCDC9 CEP170B	8.31e-05	193	122	7	1961_DN
Drug	Terbutaline hemisulfate [23031-32-5]; Down 200; 7.2uM; PC3; HT_HG-U133A	PIDD1 ZNF771 VPS13D PAK3 ZFHX2 EDRF1 ARAP1	8.31e-05	193	122	7	5764_DN
Drug	Ajmaline [4360-12-7]; Down 200; 12.2uM; HL60; HG-U133A	RBM10 PIDD1 DIDO1 ZNF710 PRKD3 PAK1IP1 CLEC16A	8.31e-05	193	122	7	1749_DN
Drug	Dirithromycin [62013-04-1]; Down 200; 4.8uM; HL60; HG-U133A	RBM10 PIDD1 DIDO1 ZNF710 MZF1 PAK1IP1 NMT1	8.58e-05	194	122	7	1712_DN
Drug	11-deoxy-16,16-dimethyl Prostaglandin E2; Down 200; 10uM; PC3; HT_HG-U133A	BACH2 PLEKHB1 PTPN12 CDK13 RERE GNAS GPRIN2	8.58e-05	194	122	7	7538_DN
Drug	Demeclocycline hydrochloride [64-73-3]; Down 200; 8uM; MCF7; HT_HG-U133A	MAP1B PIDD1 PRKD3 MZF1 CACNA1H NMT1 ARAP1	8.58e-05	194	122	7	3604_DN
Drug	monastrol; Up 200; 100uM; MCF7; HG-U133A	THSD4 CHERP PLEKHB1 ZNF710 VPS13D GNAS ARAP1	8.86e-05	195	122	7	596_UP
Drug	Furazolidone [67-45-8]; Down 200; 17.8uM; MCF7; HT_HG-U133A	PRKD3 SSPN VPS13D LLGL1 ZFHX2 EDRF1 ARAP1	8.86e-05	195	122	7	3358_DN
Drug	Pregnenolone [145-13-1]; Down 200; 12.6uM; MCF7; HT_HG-U133A	PIDD1 DIDO1 PLEKHB1 VPS13D MZF1 EDRF1 ARAP1	9.15e-05	196	122	7	2856_DN
Drug	Methoxy-8-psoralen [298-81-7]; Down 200; 18.6uM; MCF7; HT_HG-U133A	MKNK2 PIDD1 PLEKHB1 ZNF710 SSPN PKNOX1 NMT1	9.15e-05	196	122	7	5007_DN
Drug	Baclofen (R,S) [1134-47-0]; Up 200; 18.8uM; MCF7; HT_HG-U133A	UNC13B PRKD3 PKNOX1 ZFHX2 NUMB CACNA1H PRRC2A	9.15e-05	196	122	7	1536_UP
Drug	Alclometasone dipropionate [667634-13-2]; Down 200; 7.6uM; MCF7; HT_HG-U133A	DIDO1 CISH VPS13D YJU2B MZF1 PKNOX1 ARAP1	9.44e-05	197	122	7	6229_DN
Drug	FK-506; Up 200; 1uM; MCF7; HG-U133A	CHERP ATG13 RBM10 MAP7D1 MZF1 PAK2 CACNA1H	9.44e-05	197	122	7	284_UP
Drug	Oxamniquine [21738-42-1]; Up 200; 14.4uM; MCF7; HT_HG-U133A	THSD4 SSPN VPS13D CDK13 ZFHX2 LYL1 NMT1	9.44e-05	197	122	7	7344_UP
Drug	(+/-)-verapamil hydrochloride; Down 200; 10uM; MCF7; HG-U133A	CHERP ATG13 MAP7 CISH PAK2 CDC5L DEK	9.44e-05	197	122	7	161_DN
Drug	2-propylpentanoic acid; Down 200; 500uM; HL60; HT_HG-U133A	KMT2B DIDO1 CISH MAP7D1 PKNOX1 NMT1 CLUH	9.44e-05	197	122	7	1181_DN
Drug	Ceftazidime pentahydrate [78439-06-2]; Down 200; 6.2uM; HL60; HG-U133A	ELOB PIDD1 HSPBP1 VPS13D ARAP3 MZF1 NMT1	9.75e-05	198	122	7	1721_DN
Drug	2-propylpentanoic acid; Down 200; 500uM; MCF7; HG-U133A	KMT2B ZNF710 VPS13D LLGL1 MZF1 PAK1IP1 NMT1	9.75e-05	198	122	7	347_DN
Drug	GBR 12909 dihydrochloride [67469-78-7]; Down 200; 7.6uM; HL60; HG-U133A	PIDD1 CISH VPS13D PAK2 PAK1IP1 NMT1 ARAP1	9.75e-05	198	122	7	1625_DN
Drug	Niacin [59-67-6]; Down 200; 32.4uM; MCF7; HT_HG-U133A	KMT2B ZNF771 PKNOX1 ZFHX2 NUMB CACNA1H CCDC9	1.01e-04	199	122	7	3381_DN
Drug	Metolazone [17560-51-9]; Up 200; 11uM; PC3; HG-U133A	ELOB KMT2B ZNF771 VPS13D MZF1 PRRC2A RAD23A	1.01e-04	199	122	7	1932_UP
Drug	Aceclofenac [89796-99-6]; Up 200; 11.2uM; MCF7; HT_HG-U133A	PLEKHB1 AHDC1 SH3D21 LLGL1 PKNOX1 RERE NMT1	1.01e-04	199	122	7	7029_UP
Drug	Terazosin hydrochloride [63590-64-7]; Down 200; 9.4uM; MCF7; HT_HG-U133A	MAP1B ZNF710 SSPN VPS13D GNAS LYL1 GPRIN2	1.01e-04	199	122	7	6092_DN
Drug	Tinidazole [19387-91-8]; Down 200; 16.2uM; MCF7; HT_HG-U133A	DIDO1 PLEKHB1 PTPN12 NUMB PRRC2A CCDC9 CEP170B	1.01e-04	199	122	7	3430_DN
Drug	rosiglitazone; Down 200; 10uM; MCF7; HT_HG-U133A	PLEKHB1 CDK13 PIN4 PKNOX1 NUMB NMT1 PRRC2A	1.04e-04	200	122	7	6992_DN
Drug	Pergolide mesylate [66104-23-2]; Up 200; 9.8uM; MCF7; HT_HG-U133A	ATG13 PLEKHB1 PRKD3 ZNF771 PKNOX1 RERE ARAP1	1.04e-04	200	122	7	7031_UP
Drug	Apramycin [37321-09-8]; Down 200; 7.4uM; MCF7; HT_HG-U133A	RBM10 SSPN VPS13D MZF1 CDK13 PIN4 NMT1	1.04e-04	200	122	7	4959_DN
Disease	basophil count, eosinophil count	ELOB BACH2 BEND3 BRD3 PAK2 RERE CLEC16A TNXB	6.34e-06	241	119	8	EFO_0004842, EFO_0005090
Disease	vascular endothelial growth factor measurement	ZNF710 KCNC3 RORA CDC5L	7.85e-05	56	119	4	EFO_0004762
Disease	Hypertrophic Cardiomyopathy	OBSCN PDLIM3 TP53 MYBPC3	8.42e-05	57	119	4	C0007194
Disease	eosinophil count	ELOB ZFAT CHERP BACH2 BEND3 BRD3 SEC31A SAMD15 CISH PAK2 RORA CACNA1H RERE CLEC16A TNXB CCDC9 TP53	9.97e-05	1488	119	17	EFO_0004842
Disease	colorectal cancer (is_implicated_in)	RBM10 BCOR IER2 PTPN12 TP53	1.34e-04	121	119	5	DOID:9256 (is_implicated_in)
Disease	chordin-like protein 1 measurement	RTL9 PAK3	1.60e-04	5	119	2	EFO_0020257
Disease	Bilateral Wilms Tumor	BCOR MAP3K4 TP53	2.16e-04	29	119	3	C2930471
Disease	lymphocyte count	ZFAT BACH2 BEND3 BRD3 CASZ1 ZNF710 GTF2IRD2B SSPN PTPN12 SEPTIN3 CDK13 GTF2IRD2 PAK2 RERE CDC5L CLEC16A	2.68e-04	1464	119	16	EFO_0004587
Disease	seasonal allergic rhinitis	CLEC4F RORA CLEC16A	2.91e-04	32	119	3	EFO_0003956
Disease	Nephroblastoma	BCOR MAP3K4 TP53	4.14e-04	36	119	3	C0027708
Disease	Glucocorticoid use measurement	BACH2 RORA CLEC16A	5.26e-04	39	119	3	EFO_0009942
Disease	Colorectal Carcinoma	UNC13B MAP1B RBM10 OBSCN ARAP3 PKNOX1 GNAS SPAG17 EDRF1 TP53	5.66e-04	702	119	10	C0009402
Disease	Liver Diseases, Parasitic	GNAS TP53	5.70e-04	9	119	2	C0023897
Disease	Inhalant adrenergic use measurement	BACH2 RORA RERE CLEC16A	6.28e-04	96	119	4	EFO_0009941
Disease	Adrenal Gland Neoplasms	GNAS TP53	8.66e-04	11	119	2	C0001624
Disease	Adrenal Cancer	GNAS TP53	8.66e-04	11	119	2	C0750887
Disease	adult onset asthma	BACH2 RORA RERE CLEC16A	1.35e-03	118	119	4	EFO_1002011
Disease	diffuse idiopathic skeletal hyperostosis	RORA CDC5L	1.64e-03	15	119	2	EFO_0007236
Disease	osteosarcoma (is_implicated_in)	CDC5L TP53	1.87e-03	16	119	2	DOID:3347 (is_implicated_in)
Disease	testosterone measurement	CAMP ESRRG LIPE PIN4 RTL9 RORA MYOCD YY1AP1 MYO15A TP53 TNS3 ARAP1 IGSF23	1.93e-03	1275	119	13	EFO_0004908
Disease	allergic rhinitis	BACH2 RORA RERE CLEC16A	2.10e-03	133	119	4	EFO_0005854
Disease	Alzheimer disease, brain volume measurement	PAK2 RORA	2.11e-03	17	119	2	EFO_0006930, MONDO_0004975
Disease	neutrophil percentage of granulocytes	BACH2 BEND3 BRD3 RERE CLEC16A	2.36e-03	228	119	5	EFO_0007994
Disease	eosinophil percentage of granulocytes	BACH2 BEND3 BRD3 RERE CLEC16A	2.64e-03	234	119	5	EFO_0007996
Disease	serum albumin measurement	ZFAT BEND3 PRR12 LLGL1 RTL9 RORA TP53 MYBPC3	2.81e-03	592	119	8	EFO_0004535
Disease	respiratory system disease	BACH2 RORA RERE CLEC16A	2.87e-03	145	119	4	EFO_0000684
Disease	asthma, age at onset	BACH2 RORA CLEC16A	2.88e-03	70	119	3	EFO_0004847, MONDO_0004979
Disease	alopecia	CASZ1 SSPN RORA CDC5L SPAG17	2.99e-03	241	119	5	MONDO_0004907
Disease	eosinophil percentage of leukocytes	ZFAT KMT2B BACH2 BEND3 BRD3 CISH RORA RERE CLEC16A	3.30e-03	746	119	9	EFO_0007991
Disease	JT interval	OBSCN BEND3 CASZ1 CDK13 CLUH	3.38e-03	248	119	5	EFO_0007885
Disease	unipolar depression, bipolar disorder, schizophrenia, sex interaction measurement	THSD4 ZFAT PI16	3.63e-03	76	119	3	EFO_0003761, EFO_0008343, MONDO_0004985, MONDO_0005090
Disease	aspartate aminotransferase measurement	OBSCN BRD3 PRAG1 SEPTIN3 RORA MYO15A CLEC16A PRRC2A TP53 MYBPC3	3.66e-03	904	119	10	EFO_0004736
Disease	Paroxysmal atrial fibrillation	CASZ1 SSPN PAK2 MYOCD	3.73e-03	156	119	4	C0235480
Disease	familial atrial fibrillation	CASZ1 SSPN PAK2 MYOCD	3.73e-03	156	119	4	C3468561
Disease	Persistent atrial fibrillation	CASZ1 SSPN PAK2 MYOCD	3.73e-03	156	119	4	C2585653

Protein segments in the cluster

Peptide	Gene	Start	Entry
KDPPSMATEAPPCVT	PI16	271	Q6UXB8
APTEAPDMAKVAPKP	UNC13A	391	Q9UPW8
EMEEPPPPDSSPTDI	CHTF18	116	Q8WVB6
DVEMDRKQPSPAPTP	BACH2	306	Q9BYV9
EAPALPAPAAPMVSK	BRD3	421	Q15059
DTDPMVNPPDSPETE	ATG13	406	O75143
NPETKPARPDPIDMD	CDC5L	131	Q99459
LDPKSDSAMEPSPSP	ARAP3	71	Q8WWN8
PSVTPAAADPLMTPE	AMBN	376	Q9NP70
FPASAAETKPPMAPS	CASZ1	1071	Q86V15
TPALPMPKEDAPSDP	CISH	181	Q9NSE2
MPKEDAPSDPALPAP	CISH	186	Q9NSE2
AETFPKLVPPPSAMA	AHDC1	941	Q5TGY3
AQKEMSPSPPAAQDP	CEP170B	981	Q9Y4F5
PVSEPPADQVASDMP	BCOR	1111	Q6W2J9
PMDPTESPAAPEAAL	CGAS	31	Q8N884
EFLRDVEPSKMPPPD	CDK13	996	Q14004
MSHPPPAAREDKSPS	RAD23A	111	P54725
MDLPKLASDDRPSPP	RBM10	711	P98175
SAAEILPAVPMEPKP	NOBOX	386	O60393
PEPPEAALSPMSIDS	LLGL1	1001	Q15334
VSPTEMVAKFQPPPE	BEND3	231	Q5T5X7
KAMIPPTPLPTNDVD	APLP2	361	Q06481
MSDGLDNEEKPPAPP	PAK3	1	O75914
SVSPMDEPVPDSESP	MAP1B	1376	P46821
VPAPVKDEGPMVSAP	MAP6	621	Q96JE9
TPAEPEVGPAAPAMA	MAP7	416	Q14244
MADESETAVKPPAPP	NMT1	1	P30419
MENKEAGTPPPIPSR	SLC2A7	1	Q6PXP3
VPSPTLQPEDPAADM	MYO15A	971	Q9UKN7
PAPFEMPSSVSEDPS	EDRF1	246	Q3B7T1
FSPMPSEEKAASPPR	ANLN	171	Q9NQW6
AEPPDPLPDKMRQSV	PCNX3	1031	Q9H6A9
LPVSGMDKPVFTDPP	PIN4	101	Q9Y237
PDMPASQPIDIPDAK	MKNK2	46	Q9HBH9
PPAATSDPPAEDMLV	MTSS2	711	Q765P7
SPPFEKESEPESPMD	PARG	291	Q86W56
EEPSPPEDKMFFLDP	PRKD3	361	O94806
FMDEDPPKPPKVEVS	KMT2B	546	Q9UMN6
SPVPEMPTLPAEGSD	KIAA1549L	221	Q6ZVL6
MEEPQSDPSVEPPLS	TP53	1	P04637
SPVMPPPEEAAAVSA	GGN	81	Q86UU5
PDQKAEKSPPPMDSA	MYOCD	271	Q8IZQ8
SAQPEPPSPMAEEEL	OBSCN	7331	Q5VST9
MSDNGELEDKPPAPP	PAK2	1	Q13177
ELEDKPPAPPVRMSS	PAK2	6	Q13177
PTEAEPMEPDPTLSL	IGSF23	136	A1L1A6
MAAPPEPGEPEERKS	COX20	1	Q5RI15
QMEAEVKATPPPPAP	CHERP	346	Q8IWX8
PDDSKPPIQMPGSSE	CHERP	376	Q8IWX8
PPELPDVMKPQDSGS	ELOB	96	Q15370
SPETSPKETPMQPPE	CCDC9	386	Q9Y3X0
QPASEKEPEMPGPRE	DEK	16	P35659
PEKIYAMPDPTVPDS	ESRRG	246	P62508
AMPDPTVPDSDIKAL	ESRRG	251	P62508
VMAPDVPATPVAPTE	CC2D1B	366	Q5T0F9
APDPAPDSADEVMPE	DIDO1	891	Q9BTC0
LDPRPTMDGDPDTPK	CAMP	61	P49913
MASDLDFSPPEVPEP	MANBAL	1	Q9NQG1
DPSEPSPADQAPMVL	MARCHF10	121	Q8NA82
EKAEMVCAPSPAPAP	LYL1	16	P12980
DTPPDTPPAMKNATS	MAP7D1	46	Q3KQU3
TPTECPSMLEDPKLP	CCDC168	6276	Q8NDH2
APEEEGNPPESMKPA	GPRIN2	61	O60269
PMEDSTPLVPSEEPN	GTF2IRD2	266	Q86UP8
PMEDSTPLVPSEEPN	GTF2IRD2B	266	Q6EKJ0
KMSPPCISVEPPAED	CACNA1H	2186	O95180
LESAMETDPDPVPPT	SAMD15	151	Q9P1V8
EEMPEKPVASPLGPA	PRRT3	81	Q5FWE3
PPEAFEMPLTADPTL	LIPE	571	Q05469
DAPSSPVAALIPEMP	PIDD1	301	Q9HB75
PFPEPMDTQEAPTAE	IER2	91	Q9BTL4
PEDPFSSAPMTKPVT	NUMB	341	P49757
IVPASPTDPCVEMDP	MUC3B	691	Q9H195
PPAFAVTPAAAMEEP	MAP3K4	11	Q9Y6R4
MAEPLPPDAPAVSSE	GOLGA8A	311	A7E2F4
MAITAGSEEPDPPPE	HSPBP1	51	Q9NZL4
LPKPAPDAEAMSPAL	RTL9	336	Q8NET4
PNDKDPVVVPFPTMT	DARS2	306	Q6PI48
SVEESPALEAPPMDK	SH3D21	336	A4FU49
SPPPVESQTPMDVDK	PKNOX1	41	P55347
MAEEPQTPAENAPKP	NAP1L5	51	Q96NT1
MATPTQTPTKAPEEP	FXYD7	1	P58549
PPPEEAMPFEAEQPS	GNAS	96	Q5JWF2
DKSPDPNPIMTDTPI	NEO1	1176	Q92859
MVSSIEPEKQDSPPP	PTPN12	321	Q05209
EDDKGMRSETPPVPP	PRRC2A	816	P48634
PPAADAAGPDDMEPK	SSPN	16	Q14714
ETPLMSEPTASVPPE	PDLIM3	216	Q53GG5
PPPFMFKPVKEEDDG	RERE	551	Q9P2R6
SEKPPEQTPETAMPE	PRR12	1711	Q9ULL5
EQTPETAMPEPPAPE	PRR12	1716	Q9ULL5
LPPFPSPADVKETMT	TNS3	806	Q68CZ2
KPVLEAMPTSEAPQP	SPAG17	381	Q6Q759
APARVMTKKEEPPPS	ARAP1	241	Q96P48
EVDSVAMAPAAPKIP	CLEC4F	21	Q8N1N0
AQSPADAPMSPELPK	CLEC16A	931	Q2KHT3
PNPEEAETESESMPP	CNGB1	41	Q14028
AEEPMATEPAPAGAP	CLUH	1276	O75153
ELTKPPPLMAAEPTA	TBC1D24	451	Q9ULP9
RKEPEAPGEMPAPAV	ZFAT	546	Q9P243
IPMDNKEVPGEAPAP	ZNF771	41	Q7L3S4
CSPAPSRKPEAMDEP	UNC80	3136	Q8N2C7
LDEEVMALSPPSPPT	ZFHX2	336	Q9C0A1
PEPPPSYDEAVKMAK	TMEM52	151	Q8NDY8
MESAPAAPDPAASEP	RORA	1	P35398
PVPPDSALESPFEEM	PLEKHB1	6	Q9UF11
DAAMSELVPEPRPKP	SEPTIN3	11	Q9UH03
SPTEPSMEAPEPAEE	TNXB	2081	P22105
EEMAPASTEPPTPEP	TNXB	2286	P22105
LSDPEAPSMESPEPV	ZNF710	226	Q8N1W2
APSMESPEPVKPEQG	ZNF710	231	Q8N1W2
PKEMKEDATTHPPPD	UNC13B	331	O14795
MSPGDCPPETTETPK	YJU2B	331	P13994
VADMKESLPPAAEPS	PAK1IP1	306	Q9NWT1
SMLSSPDAPKDPVPA	PRAG1	1061	Q86YV5
ESFESPAALPAMPPE	YY1AP1	521	Q9H869
PELSPSVMPEAPLES	ZFYVE27	11	Q5T4F4
PVEAMAPPVEAGAAP	TEX13A	206	Q9BXU3
DFDFSPMSDKNPEPP	TMEM130	376	Q8N3G9
APSPLPKMADVSAEE	UBAC1	96	Q9BSL1
SMKPTPEEEPCNIFP	THSD4	661	Q6ZMP0
ATPMTPGAKTQPPED	SEC31A	156	O94979
SPAKPAAPEDPQMPA	PRRT1B	26	A0A1B0GWB2
SSPEPAPPSEAMDAD	PPP1R10	336	Q96QC0
MAEESRKPSAPSPPD	ZKSCAN8	1	Q15776
PMELRLDSPSAPDKP	VPS13D	3061	Q5THJ4
APDKPVVLPAIMPGD	VPS13D	3071	Q5THJ4
DQPAMSPEDKSPITP	KCNC3	681	Q14003
EAEKAEPMLAPAPAP	MYBPC3	96	Q14896
KMEPSSFQPLPETEP	MZF1	146	P28698