Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyCellularComponent	actomyosin contractile ring	MYH9 ANLN	6.02e-05	7	36	2	GO:0005826
GeneOntologyCellularComponent	synaptonemal complex	MSH5 BRCA1 BRCA2	6.77e-05	46	36	3	GO:0000795
GeneOntologyCellularComponent	synaptonemal structure	MSH5 BRCA1 BRCA2	6.77e-05	46	36	3	GO:0099086
GeneOntologyCellularComponent	microtubule organizing center	ODF2L FRY CCDC88A DIAPH3 BRCA1 BRCA2 GLG1 NIN	1.37e-04	919	36	8	GO:0005815
GeneOntologyCellularComponent	contractile ring	MYH9 ANLN	2.59e-04	14	36	2	GO:0070938
GeneOntologyCellularComponent	cell division site	MYH9 DIAPH3 ANLN	3.52e-04	80	36	3	GO:0032153
GeneOntologyCellularComponent	lateral element	BRCA1 BRCA2	4.84e-04	19	36	2	GO:0000800
GeneOntologyCellularComponent	condensed nuclear chromosome	MSH5 BRCA1 BRCA2	5.14e-04	91	36	3	GO:0000794
GeneOntologyCellularComponent	lamellipodium	MYH9 CCDC88A FGD6 PLCE1	6.38e-04	230	36	4	GO:0030027
GeneOntologyCellularComponent	DNA repair complex	BRCA1 BRCA2	7.13e-04	23	36	2	GO:1990391
GeneOntologyCellularComponent	centrosome	ODF2L FRY CCDC88A BRCA1 BRCA2 NIN	1.85e-03	770	36	6	GO:0005813
GeneOntologyCellularComponent	centriole	ODF2L CCDC88A NIN	3.20e-03	172	36	3	GO:0005814
GeneOntologyCellularComponent	nuclear ubiquitin ligase complex	BRCA1 BRCA2	3.22e-03	49	36	2	GO:0000152
GeneOntologyCellularComponent	cleavage furrow	MYH9 DIAPH3	4.95e-03	61	36	2	GO:0032154
GeneOntologyCellularComponent	spindle pole	FRY DIAPH3 NIN	5.23e-03	205	36	3	GO:0000922
HumanPheno	Abnormal peritoneum morphology	BRCA1 BRCA2 ANLN PLCE1	2.97e-05	65	15	4	HP:0002585
MousePheno	abnormal cell cycle	MORC1 MSH5 DIAPH3 BRCA1 BRCA2 BRDT NIN	7.24e-05	520	29	7	MP:0003077
MousePheno	azoospermia	MORC1 MSH5 BRCA1 BRCA2 BRDT	1.31e-04	244	29	5	MP:0005159
MousePheno	ovary degeneration	MSH5 BRCA2	1.48e-04	9	29	2	MP:0013236
MousePheno	absent gametes	MORC1 MSH5 BRCA1 BRCA2 BRDT	1.64e-04	256	29	5	MP:0001117
Domain	Retinoid-X_rcpt/HNF4	NR2E3 NR2E1	1.43e-04	10	34	2	IPR000003
Domain	zf-C4	NR2E3 NR2E1	3.17e-03	46	34	2	PF00105
Domain	NUCLEAR_REC_DBD_1	NR2E3 NR2E1	3.17e-03	46	34	2	PS00031
Domain	Znf_hrmn_rcpt	NR2E3 NR2E1	3.17e-03	46	34	2	IPR001628
Domain	Nuclear_hrmn_rcpt	NR2E3 NR2E1	3.17e-03	46	34	2	IPR001723
Domain	ZnF_C4	NR2E3 NR2E1	3.17e-03	46	34	2	SM00399
Domain	NUCLEAR_REC_DBD_2	NR2E3 NR2E1	3.17e-03	46	34	2	PS51030
Domain	-	NR2E3 NR2E1	3.30e-03	47	34	2	1.10.565.10
Domain	HOLI	NR2E3 NR2E1	3.44e-03	48	34	2	SM00430
Domain	Nucl_hrmn_rcpt_lig-bd	NR2E3 NR2E1	3.44e-03	48	34	2	IPR000536
Domain	Hormone_recep	NR2E3 NR2E1	3.44e-03	48	34	2	PF00104
Domain	-	NR2E3 NR2E1	4.82e-03	57	34	2	3.30.50.10
Domain	Znf_NHR/GATA	NR2E3 NR2E1	4.99e-03	58	34	2	IPR013088
Domain	IQ	SCN10A MYH9	7.39e-03	71	34	2	PF00612
Domain	IQ_motif_EF-hand-BS	SCN10A MYH9	1.17e-02	90	34	2	IPR000048
Domain	IQ	SCN10A MYH9	1.24e-02	93	34	2	PS50096
Pathway	WP_NEPHROTIC_SYNDROME	MYH9 ANLN PLCE1	5.15e-05	45	23	3	M39864
Pathway	KEGG_MEDICUS_REFERENCE_HOMOLOGOUS_RECOMBINATION_IN_ICLR	BRCA1 BRCA2	3.01e-04	16	23	2	M47855
Pathway	REACTOME_MEIOTIC_RECOMBINATION	MSH5 BRCA1 BRCA2	3.80e-04	88	23	3	M1011
Pathway	BIOCARTA_ATRBRCA_PATHWAY	BRCA1 BRCA2	4.28e-04	19	23	2	MM1478
Pathway	REACTOME_SIGNALING_BY_RHO_GTPASES_MIRO_GTPASES_AND_RHOBTB3	TAOK3 MYH9 CCDC88A DIAPH3 DSP ANLN	4.79e-04	649	23	6	MM15690
Pathway	BIOCARTA_ATRBRCA_PATHWAY	BRCA1 BRCA2	5.77e-04	22	23	2	M9703
Pathway	REACTOME_RHO_GTPASE_CYCLE	TAOK3 CCDC88A DIAPH3 DSP ANLN	6.05e-04	439	23	5	MM15595
Pathway	REACTOME_RHO_GTPASE_CYCLE	TAOK3 CCDC88A DIAPH3 DSP ANLN	6.77e-04	450	23	5	M27078
Pathway	REACTOME_HOMOLOGOUS_DNA_PAIRING_AND_STRAND_EXCHANGE	BRCA1 BRCA2	8.08e-04	26	23	2	MM15297
Pathway	REACTOME_SIGNALING_BY_RHO_GTPASES_MIRO_GTPASES_AND_RHOBTB3	TAOK3 MYH9 CCDC88A DIAPH3 DSP ANLN	8.31e-04	720	23	6	M41838
Pathway	REACTOME_RESOLUTION_OF_D_LOOP_STRUCTURES_THROUGH_SYNTHESIS_DEPENDENT_STRAND_ANNEALING_SDSA	BRCA1 BRCA2	8.72e-04	27	23	2	M27586
Pathway	REACTOME_MEIOSIS	MSH5 BRCA1 BRCA2	9.41e-04	120	23	3	M529
Pathway	KEGG_MEDICUS_REFERENCE_HOMOLOGOUS_RECOMBINATION	BRCA1 BRCA2	1.30e-03	33	23	2	M47842
Pathway	REACTOME_RESOLUTION_OF_D_LOOP_STRUCTURES	BRCA1 BRCA2	1.47e-03	35	23	2	MM15293
Pathway	WP_MALE_INFERTILITY	MSH5 BRCA2 BRDT	1.62e-03	145	23	3	M39856
Pathway	REACTOME_RESOLUTION_OF_D_LOOP_STRUCTURES	BRCA1 BRCA2	1.64e-03	37	23	2	M27583
Pathway	WP_BREAST_CANCER_PATHWAY	FZD10 BRCA1 BRCA2	1.93e-03	154	23	3	M39739
Pathway	REACTOME_REPRODUCTION	MSH5 BRCA1 BRCA2	2.08e-03	158	23	3	M26956
Pathway	REACTOME_RND3_GTPASE_CYCLE	CCDC88A DSP	2.11e-03	42	23	2	MM15677
Pathway	REACTOME_RND3_GTPASE_CYCLE	CCDC88A DSP	2.11e-03	42	23	2	M41826
Pathway	REACTOME_RND1_GTPASE_CYCLE	CCDC88A DSP	2.11e-03	42	23	2	M41828
Pathway	REACTOME_RND1_GTPASE_CYCLE	CCDC88A DSP	2.21e-03	43	23	2	MM15679
Pathway	REACTOME_HOMOLOGOUS_DNA_PAIRING_AND_STRAND_EXCHANGE	BRCA1 BRCA2	2.21e-03	43	23	2	M27588
Pathway	PID_FANCONI_PATHWAY	BRCA1 BRCA2	2.63e-03	47	23	2	M1
Pathway	WP_PRIMARY_OVARIAN_INSUFFICIENCY	MSH5 BRCA1 BRCA2	2.73e-03	174	23	3	M48058
Pathway	REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY	NR2E3 NR2E1	2.74e-03	48	23	2	MM14987
Pathway	REACTOME_DISEASES_OF_DNA_REPAIR	BRCA1 BRCA2	3.09e-03	51	23	2	M29854
Pathway	REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY	NR2E3 NR2E1	3.34e-03	53	23	2	M8276
Pathway	WP_DNA_IRDOUBLE_STRAND_BREAKS_AND_CELLULAR_RESPONSE_VIA_ATM	BRCA1 BRCA2	3.59e-03	55	23	2	M39598
Pubmed	A pilot genome-wide association study of early-onset breast cancer.	BRCA1 BRCA2 GLG1	4.43e-09	4	37	3	18463975
Pubmed	Association of BRCA1/2 mutations with ovarian cancer prognosis: An updated meta-analysis.	BRCA1 BRCA2	1.10e-06	2	37	2	29480828
Pubmed	A systematic genetic assessment of 1,433 sequence variants of unknown clinical significance in the BRCA1 and BRCA2 breast cancer-predisposition genes.	BRCA1 BRCA2	1.10e-06	2	37	2	17924331
Pubmed	Attitudes, knowledge, risk perceptions and decision-making among women with breast and/or ovarian cancer considering testing for BRCA1 and BRCA2 and their spouses.	BRCA1 BRCA2	1.10e-06	2	37	2	12833555
Pubmed	Randomised trial of a decision aid and its timing for women being tested for a BRCA1/2 mutation.	BRCA1 BRCA2	1.10e-06	2	37	2	14735173
Pubmed	Allelic imbalance in BRCA1 and BRCA2 gene expression is associated with an increased breast cancer risk.	BRCA1 BRCA2	1.10e-06	2	37	2	18204050
Pubmed	Clinical outcomes of breast cancer in carriers of BRCA1 and BRCA2 mutations.	BRCA1 BRCA2	1.10e-06	2	37	2	17625123
Pubmed	Brain Metastases in Pancreatic Ductal Adenocarcinoma: Assessment of Molecular Genotype-Phenotype Features-An Entity With an Increasing Incidence?	BRCA1 BRCA2	1.10e-06	2	37	2	29496399
Pubmed	High risk for ovarian cancer in a prospective series is restricted to BRCA1/2 mutation carriers.	BRCA1 BRCA2	1.10e-06	2	37	2	19010876
Pubmed	Coffee consumption and breast cancer risk among BRCA1 and BRCA2 mutation carriers.	BRCA1 BRCA2	1.10e-06	2	37	2	16032702
Pubmed	BRCA1 and BRCA2 germline testing in Cretan isolates reveals novel and strong founder effects.	BRCA1 BRCA2	1.10e-06	2	37	2	32022259
Pubmed	Effect of BRCA1/2 Mutational Status on Survival Outcomes According to Secondary Cytoreductive Surgery and Maintenance Therapy in Platinum-Sensitive Relapsed Ovarian Cancer: A Real-World Evidence Study.	BRCA1 BRCA2	1.10e-06	2	37	2	35879854
Pubmed	Oral contraceptive use and BRCA penetrance: a case-only study.	BRCA1 BRCA2	1.10e-06	2	37	2	19549808
Pubmed	Prevalence of BRCA1 and BRCA2 Mutations Among Patients With Ovarian, Primary Peritoneal, and Fallopian Tube Cancer in India: A Multicenter Cross-Sectional Study.	BRCA1 BRCA2	1.10e-06	2	37	2	34101484
Pubmed	CRISPR/Cas9-mediated knock-in of BRCA1/2 mutations restores response to olaparib in pancreatic cancer cell lines.	BRCA1 BRCA2	1.10e-06	2	37	2	37907567
Pubmed	Olaparib monotherapy in patients with advanced relapsed ovarian cancer and a germline BRCA1/2 mutation: a multistudy analysis of response rates and safety.	BRCA1 BRCA2	1.10e-06	2	37	2	26961146
Pubmed	Expansion of Cancer Risk Profile for BRCA1 and BRCA2 Pathogenic Variants.	BRCA1 BRCA2	1.10e-06	2	37	2	35420638
Pubmed	[BRCA1 and BRCA2 mutations in families studied in the program of genetic counselling in cancer of the Valencian community (Spain)].	BRCA1 BRCA2	1.10e-06	2	37	2	18279628
Pubmed	Predicting BRCA1 and BRCA2 gene mutation carriers: comparison of PENN II model to previous study.	BRCA1 BRCA2	1.10e-06	2	37	2	20512419
Pubmed	Deleterious and ethnic-related BRCA1/2 mutations in tissue and blood of Egyptian colorectal cancer patients and its correlation with human papillomavirus.	BRCA1 BRCA2	1.10e-06	2	37	2	37804357
Pubmed	BRCAPRO 6.0 Model Validation in Male Patients Presenting for BRCA Testing.	BRCA1 BRCA2	1.10e-06	2	37	2	25948675
Pubmed	Common breast cancer susceptibility alleles are associated with tumour subtypes in BRCA1 and BRCA2 mutation carriers: results from the Consortium of Investigators of Modifiers of BRCA1/2.	BRCA1 BRCA2	1.10e-06	2	37	2	22053997
Pubmed	Germ-line mutations in BRCA1 or BRCA2 in the normal breast are associated with altered expression of estrogen-responsive proteins and the predominance of progesterone receptor A.	BRCA1 BRCA2	1.10e-06	2	37	2	14732925
Pubmed	BRCA mutations in women with inflammatory breast cancer.	BRCA1 BRCA2	1.10e-06	2	37	2	29044548
Pubmed	Mutations in BRCA1 and BRCA2 differentially affect the tumor microenvironment and response to checkpoint blockade immunotherapy.	BRCA1 BRCA2	1.10e-06	2	37	2	33834176
Pubmed	Screening, Active Surveillance, and Treatment of Localized Prostate Cancer Among Carriers of Germline BRCA Mutations.	BRCA1 BRCA2	1.10e-06	2	37	2	31147265
Pubmed	Should genetic testing for BRCA1/2 be permitted for minors? Opinions of BRCA mutation carriers and their adult offspring.	BRCA1 BRCA2	1.10e-06	2	37	2	18200524
Pubmed	Enhanced response rate to pegylated liposomal doxorubicin in high grade serous ovarian carcinomas harbouring BRCA1 and BRCA2 aberrations.	BRCA1 BRCA2	1.10e-06	2	37	2	29298688
Pubmed	Fertility in women with BRCA mutations: a case-control study.	BRCA1 BRCA2	1.10e-06	2	37	2	19200971
Pubmed	Prevalence of BRCA mutations and founder effect in high-risk Hispanic families.	BRCA1 BRCA2	1.10e-06	2	37	2	16030099
Pubmed	BRCA1/2 germline missense mutations: a systematic review.	BRCA1 BRCA2	1.10e-06	2	37	2	28277317
Pubmed	Adequacy of risk-reducing gynaecologic surgery in BRCA1 or BRCA2 mutation carriers and other women at high risk of pelvic serous cancer.	BRCA1 BRCA2	1.10e-06	2	37	2	21424757
Pubmed	Large genomic rearrangement in BRCA1 and BRCA2 and clinical characteristics of men with breast cancer in the United States.	BRCA1 BRCA2	1.10e-06	2	37	2	17592676
Pubmed	Gene promoter hypermethylation in ductal lavage fluid from healthy BRCA gene mutation carriers and mutation-negative controls.	BRCA1 BRCA2	1.10e-06	2	37	2	17324252
Pubmed	Prevalence of BRCA1 and BRCA2 large genomic rearrangements in Tunisian high risk breast/ovarian cancer families: Implications for genetic testing.	BRCA1 BRCA2	1.10e-06	2	37	2	28212807
Pubmed	Genetic counseling impacts decision for prophylactic surgery for patients perceived to be at high risk for breast cancer.	BRCA1 BRCA2	1.10e-06	2	37	2	11448436
Pubmed	No evidence of excess breast cancer risk among mutation-negative women from BRCA mutation-positive families.	BRCA1 BRCA2	1.10e-06	2	37	2	20458532
Pubmed	BRCA1 and BRCA2 germline mutation spectrum in hereditary breast/ovarian cancer families from Maghrebian countries.	BRCA1 BRCA2	1.10e-06	2	37	2	23697973
Pubmed	Rapid evolution of BRCA1 and BRCA2 in humans and other primates.	BRCA1 BRCA2	1.10e-06	2	37	2	25011685
Pubmed	BRCA1 and BRCA2 unclassified variants and missense polymorphisms in Algerian breast/ovarian cancer families.	BRCA1 BRCA2	1.10e-06	2	37	2	22684231
Pubmed	Breast magnetic resonance imaging for screening high-risk women.	BRCA1 BRCA2	1.10e-06	2	37	2	23928241
Pubmed	Assessing the RNA effect of 26 DNA variants in the BRCA1 and BRCA2 genes.	BRCA1 BRCA2	1.10e-06	2	37	2	21735045
Pubmed	Heterozygous BRCA1 and BRCA2 and Mismatch Repair Gene Pathogenic Variants in Children and Adolescents With Cancer.	BRCA1 BRCA2	1.10e-06	2	37	2	35980168
Pubmed	Loss of heterozygosity at the BRCA2 locus detected by multiplex ligation-dependent probe amplification is common in prostate cancers from men with a germline BRCA2 mutation.	BRCA1 BRCA2	1.10e-06	2	37	2	18445692
Pubmed	Tubal ligation and risk of ovarian cancer in carriers of BRCA1 or BRCA2 mutations: a case-control study.	BRCA1 BRCA2	1.10e-06	2	37	2	11377596
Pubmed	BRCA1 and BRCA2 mutations in women of different ethnicities undergoing testing for hereditary breast-ovarian cancer.	BRCA1 BRCA2	1.10e-06	2	37	2	19241424
Pubmed	BRCA mutations and risk of prostate cancer in Ashkenazi Jews.	BRCA1 BRCA2	1.10e-06	2	37	2	15131025
Pubmed	Broad BRCA1 and BRCA2 mutational spectrum and high incidence of recurrent and novel mutations in the eastern Spain population.	BRCA1 BRCA2	1.10e-06	2	37	2	20033483
Pubmed	[Several risk factors of breast cancer development and prognosis of its course].	BRCA1 BRCA2	1.10e-06	2	37	2	18663943
Pubmed	Do BRCA1 and BRCA2 mutation carriers have earlier natural menopause than their noncarrier relatives? Results from the Kathleen Cuningham Foundation Consortium for Research into Familial Breast Cancer.	BRCA1 BRCA2	1.10e-06	2	37	2	24081944
Pubmed	Prevalence and penetrance of BRCA1 and BRCA2 mutations in a population-based series of breast cancer cases. Anglian Breast Cancer Study Group.	BRCA1 BRCA2	1.10e-06	2	37	2	11044354
Pubmed	Health survey and assessment of the polymorphisms BRCA1/P871L, BRCA1/Q356R, and BRCA2/N372H in female gas station workers in Rio de Janeiro.	BRCA1 BRCA2	1.10e-06	2	37	2	28862356
Pubmed	High prevalence of BRCA1 and BRCA2 germline mutations with loss of heterozygosity in a series of resected pancreatic adenocarcinoma and other neoplastic lesions.	BRCA1 BRCA2	1.10e-06	2	37	2	23658460
Pubmed	Challenging the believed proportion of ovarian cancer attributable to BRCA2 versus BRCA1 pathogenic variants.	BRCA1 BRCA2	1.10e-06	2	37	2	31760313
Pubmed	Risk factors for non-invasive lesions of the fallopian tube in BRCA mutation carriers.	BRCA1 BRCA2	1.10e-06	2	37	2	20722102
Pubmed	BRCA1 and BRCA2 germline mutations in Moroccan breast/ovarian cancer families: novel mutations and unclassified variants.	BRCA1 BRCA2	1.10e-06	2	37	2	22425665
Pubmed	BRCA1/2 in high-risk African American women with breast cancer: providing genetic testing through various recruitment strategies.	BRCA1 BRCA2	1.10e-06	2	37	2	18752448
Pubmed	Peritoneal washing cytology in patients with BRCA1 or BRCA2 mutations undergoing risk-reducing salpingo-oophorectomies: a 10-year experience and reappraisal of its clinical utility.	BRCA1 BRCA2	1.10e-06	2	37	2	22425664
Pubmed	Effectiveness of Prophylactic Surgeries in BRCA1 or BRCA2 Mutation Carriers: A Meta-analysis and Systematic Review.	BRCA1 BRCA2	1.10e-06	2	37	2	26979395
Pubmed	Identification of BRCA1/2 founder mutations in Southern Chinese breast cancer patients using gene sequencing and high resolution DNA melting analysis.	BRCA1 BRCA2	1.10e-06	2	37	2	22970155
Pubmed	Implications of BRCA1 and BRCA2 mutations for the efficacy of paclitaxel monotherapy in advanced ovarian cancer.	BRCA1 BRCA2	1.10e-06	2	37	2	23265709
Pubmed	Assessing the usefulness of a novel MRI-based breast density estimation algorithm in a cohort of women at high genetic risk of breast cancer: the UK MARIBS study.	BRCA1 BRCA2	1.10e-06	2	37	2	19903338
Pubmed	Anti-müllerian hormone levels and antral follicle count in women with a BRCA1 or BRCA2 germline pathogenic variant: A retrospective cohort study.	BRCA1 BRCA2	1.10e-06	2	37	2	34304065
Pubmed	Absence of 185delAG and 6174delT Mutations among Breast Cancer Patients of Eastern India.	BRCA1 BRCA2	1.10e-06	2	37	2	26625823
Pubmed	Low prevalence of BRCA1 and BRCA2 mutations in the sporadic breast cancer of Spanish population.	BRCA1 BRCA2	1.10e-06	2	37	2	21918853
Pubmed	BRCA1 and BRCA2 germline mutations in 85 Iranian breast cancer patients.	BRCA1 BRCA2	1.10e-06	2	37	2	21918854
Pubmed	Novel germline mutations and unclassified variants of BRCA1 and BRCA2 genes in Chinese women with familial breast/ovarian cancer.	BRCA1 BRCA2	1.10e-06	2	37	2	26852015
Pubmed	Meta-analysis of BRCA1 and BRCA2 penetrance.	BRCA1 BRCA2	1.10e-06	2	37	2	17416853
Pubmed	Power spectral analysis of mammographic parenchymal patterns for breast cancer risk assessment.	BRCA1 BRCA2	1.10e-06	2	37	2	18175183
Pubmed	Presence of crown-like structures in breast adipose tissue; differences between healthy controls, BRCA1/2 gene mutation carriers and breast cancer patients.	BRCA1 BRCA2	1.10e-06	2	37	2	38057686
Pubmed	Germline mutations in BRCA1 and BRCA2 in epithelial ovarian cancer patients in Brazil.	BRCA1 BRCA2	1.10e-06	2	37	2	27914478
Pubmed	BRCA1 and BRCA2 germline mutations in Korean breast cancer patients at high risk of carrying mutations.	BRCA1 BRCA2	1.10e-06	2	37	2	16455195
Pubmed	The poly(ADP-ribose) polymerase inhibitor niraparib (MK4827) in BRCA mutation carriers and patients with sporadic cancer: a phase 1 dose-escalation trial.	BRCA1 BRCA2	1.10e-06	2	37	2	23810788
Pubmed	Prognostic Impact of Breast-Conserving Therapy Versus Mastectomy of BRCA1/2 Mutation Carriers Compared With Noncarriers in a Consecutive Series of Young Breast Cancer Patients.	BRCA1 BRCA2	1.10e-06	2	37	2	29727326
Pubmed	Overexpression of BRCA1 or BRCA2 in prostatectomy specimens is predictive of biochemical recurrence after radical prostatectomy.	BRCA1 BRCA2	1.10e-06	2	37	2	26272590
Pubmed	Five recurrent BRCA1/2 mutations are responsible for cancer predisposition in the majority of Slovenian breast cancer families.	BRCA1 BRCA2	1.10e-06	2	37	2	18783588
Pubmed	Risk reducing surgery with peritoneal staging in BRCA1-2 mutation carriers. A prospective study.	BRCA1 BRCA2	1.10e-06	2	37	2	35871032
Pubmed	Balancing autonomy and responsibility: the ethics of generating and disclosing genetic information.	BRCA1 BRCA2	1.10e-06	2	37	2	12672886
Pubmed	Multiplex SNaPshot for detection of BRCA1/2 common mutations in Spanish and Spanish related breast/ovarian cancer families.	BRCA1 BRCA2	1.10e-06	2	37	2	17603881
Pubmed	Cancer risk in relatives of BRCA1/2 pathogenic variant carriers in a large series of unselected patients with breast cancer.	BRCA1 BRCA2	1.10e-06	2	37	2	36861435
Pubmed	Recurrent BRCA1 and BRCA2 mutations in breast cancer patients of African ancestry.	BRCA1 BRCA2	1.10e-06	2	37	2	22739995
Pubmed	The impact of a panel of 18 SNPs on breast cancer risk in women attending a UK familial screening clinic: a case-control study.	BRCA1 BRCA2	1.10e-06	2	37	2	27794048
Pubmed	The role of BRCA1/2 in hereditary and familial breast and ovarian cancers.	BRCA1 BRCA2	1.10e-06	2	37	2	31317679
Pubmed	Breast cancer surgery trend changes since the introduction of BRCA1/2 mutation screening: a retrospective cohort analysis of 158 mutation carriers treated at a single institution.	BRCA1 BRCA2	1.10e-06	2	37	2	20972632
Pubmed	A spectrum of BRCA1 and BRCA2 germline deleterious variants in ovarian cancer in Russia.	BRCA1 BRCA2	1.10e-06	2	37	2	36367610
Pubmed	Impact of educational print materials on knowledge, attitudes, and interest in BRCA1/BRCA2: testing among Ashkenazi Jewish women.	BRCA1 BRCA2	1.10e-06	2	37	2	11550168
Pubmed	BRCA1 and BRCA2 germline mutations in Korean ovarian cancer patients.	BRCA1 BRCA2	1.10e-06	2	37	2	19499246
Pubmed	Reproductive factors and ovarian cancer risk in Jewish BRCA1 and BRCA2 mutation carriers (United States).	BRCA1 BRCA2	1.10e-06	2	37	2	12946038
Pubmed	Evaluation of chromosome 6p22 as a breast cancer risk modifier locus in a follow-up study of BRCA2 mutation carriers.	BRCA1 BRCA2	1.10e-06	2	37	2	23011509
Pubmed	Comprehensive mutational analysis of BRCA1/BRCA2 for Korean breast cancer patients: evidence of a founder mutation.	BRCA1 BRCA2	1.10e-06	2	37	2	19656164
Pubmed	Evidence of haplotype insufficiency in human cells containing a germline mutation in BRCA1 or BRCA2.	BRCA1 BRCA2	1.10e-06	2	37	2	11807777
Pubmed	Effect of pregnancy as a risk factor for breast cancer in BRCA1/BRCA2 mutation carriers.	BRCA1 BRCA2	1.10e-06	2	37	2	15986445
Pubmed	BRCAness: finding the Achilles heel in ovarian cancer.	BRCA1 BRCA2	1.10e-06	2	37	2	22673632
Pubmed	Familial breast/ovarian cancer and BRCA1/2 genetic screening: the role of immunohistochemistry as an additional method in the selection of patients.	BRCA1 BRCA2	1.10e-06	2	37	2	17625228
Pubmed	Is mammographic breast density a breast cancer risk factor in women with BRCA mutations?	BRCA1 BRCA2	1.10e-06	2	37	2	20625126
Pubmed	Prevalence of BRCA1/BRCA2 mutations in a Brazilian population sample at-risk for hereditary breast cancer and characterization of its genetic ancestry.	BRCA1 BRCA2	1.10e-06	2	37	2	27741520
Pubmed	Effect of BRCA1/2 mutations on long-term survival of patients with invasive ovarian cancer: the national Israeli study of ovarian cancer.	BRCA1 BRCA2	1.10e-06	2	37	2	18165636
Pubmed	Large genomic rearrangements in BRCA1 and BRCA2: implications for patient care.	BRCA1 BRCA2	1.10e-06	2	37	2	23615136
Pubmed	Clinicopathologic features and BRCA mutations in primary fallopian tube cancer in Japanese women.	BRCA1 BRCA2	1.10e-06	2	37	2	29982601
Pubmed	Breast cancer detection and tumor characteristics in BRCA1 and BRCA2 mutation carriers.	BRCA1 BRCA2	1.10e-06	2	37	2	28343309
Interaction	CFAP184 interactions	ODF2L CCDC88A DIAPH3 BRCA2 CCDC136 NIN	4.65e-07	162	37	6	int:CFAP184
Interaction	ETAA1 interactions	LRRC59 CCDC88A BRCA1 BRCA2 PLCE1	6.52e-06	145	37	5	int:ETAA1
Interaction	LUZP1 interactions	MYH9 CCDC88A BRCA1 ANLN NIN	2.66e-05	194	37	5	int:LUZP1
Cytoband	Ensembl 112 genes in cytogenetic band chr13q13	FRY BRCA2	2.02e-03	82	37	2	chr13q13
Cytoband	Ensembl 112 genes in cytogenetic band chr12q24	FZD10 TAOK3 MSI1	4.54e-03	415	37	3	chr12q24
Cytoband	Ensembl 112 genes in cytogenetic band chr1p22	ODF2L BRDT	5.50e-03	137	37	2	chr1p22
GeneFamily	Ring finger proteins\|Fanconi anemia complementation groups\|Protein phosphatase 1 regulatory subunits\|BRCA1 A complex\|BRCA1 B complex\|BRCA1 C complex	BRCA1 BRCA2	2.65e-04	20	22	2	548
GeneFamily	Nuclear hormone receptors	NR2E3 NR2E1	1.61e-03	49	22	2	71
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	FGD6 ANLN	2.57e-02	206	22	2	682
Coexpression	HALLMARK_MITOTIC_SPINDLE	MYH9 CCDC88A BRCA2 FGD6 ANLN NIN	3.39e-07	199	37	6	M5893
Coexpression	HE_LIM_SUN_FETAL_LUNG_C1_EARLY_STALK_CELL	NFE2L3 C5orf34 MSI1 DIAPH3 BRCA1 BRCA2 FGD6 ANLN	1.01e-06	567	37	8	M45692
Coexpression	CHIBA_RESPONSE_TO_TSA_DN	ITGA1 BRCA2 DSP	3.38e-06	21	37	3	M12459
Coexpression	RODRIGUES_THYROID_CARCINOMA_POORLY_DIFFERENTIATED_UP	AGGF1 ODF2L C5orf34 CCDC88A DIAPH3 BRCA1 ANLN	2.84e-05	644	37	7	M10501
Coexpression	HAMAI_APOPTOSIS_VIA_TRAIL_UP	AGGF1 TAOK3 CCDC88A DIAPH3 BRCA1 ANLN NIN	3.19e-05	656	37	7	M18979
Coexpression	HE_LIM_SUN_FETAL_LUNG_C5_PRO_B_CELL	C5orf34 CCDC88A DIAPH3 BRCA1 BRCA2 ANLN	5.13e-05	478	37	6	M45785
Coexpression	MONTERO_THYROID_CANCER_POOR_SURVIVAL_UP	DIAPH3 ANLN	1.27e-04	12	37	2	M11629
Coexpression	DCA_UP.V1_DN	DHX57 MTRF1 MSH5 TGFBRAP1	1.32e-04	185	37	4	M2760
Coexpression	MATZUK_SPERMATOCYTE	MORC1 MSH5 BRCA2	1.44e-04	72	37	3	M1831
Coexpression	FLORIO_NEOCORTEX_BASAL_RADIAL_GLIA_DN	MSH5 BRCA1 BRCA2 ANLN	1.47e-04	190	37	4	M761
Coexpression	MATZUK_SPERMATOCYTE	MORC1 MSH5 BRCA2	1.50e-04	73	37	3	MM1234
Coexpression	GSE23568_CTRL_VS_ID3_TRANSDUCED_CD8_TCELL_DN	DIAPH3 BRCA1 BRCA2 ANLN	1.75e-04	199	37	4	M8507
Coexpression	GSE46606_DAY1_VS_DAY3_CD40L_IL2_IL5_STIMULATED_IRF4_KO_BCELL_UP	NFE2L3 AGGF1 NR2E3 AKNAD1	1.78e-04	200	37	4	M9825
Coexpression	LAKE_ADULT_KIDNEY_C2_PODOCYTES	FRY MYH9 ITGA1 PLCE1	2.23e-04	212	37	4	M39221
Coexpression	LAZARO_GENETIC_MOUSE_MODEL_HIGH_GRADE_LARGE_CELL_NEUROENDOCRINE_LUNG_CARCINOMA_UP	ODF2L DIAPH3 BRCA1 BRCA2 ANLN	2.41e-04	402	37	5	MM454
Coexpression	KAPOSI_LIVER_CANCER_MET_UP	FGD6 PLCE1	2.92e-04	18	37	2	M5755
Coexpression	HE_LIM_SUN_FETAL_LUNG_C4_CYCLING_T_CELL	C5orf34 CCDC88A DIAPH3 BRCA1 BRCA2 ANLN NIN	2.98e-04	939	37	7	M45768
CoexpressionAtlas	dev gonad_e12.5_F_GermCellOvary_Oct_top-relative-expression-ranked_500	MORC1 BRCA1 BRCA2 BRDT DSP FGD6 ANLN	3.06e-06	406	34	7	gudmap_dev gonad_e12.5_F_GermCellOvary_Oct_500
CoexpressionAtlas	FacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_1000_k-means-cluster#3	DHX57 CCDC88A BRCA1 BRCA2 FGD6 NIN	6.13e-06	291	34	6	Facebase_RNAseq_e10.5_Lateral Nasal Eminence_1000_K3
CoexpressionAtlas	dev gonad_e12.5_F_GermCellOvary_Oct_top-relative-expression-ranked_1000	MORC1 DIAPH3 BRCA1 BRCA2 BRDT DSP FGD6 ANLN	3.61e-05	822	34	8	gudmap_dev gonad_e12.5_F_GermCellOvary_Oct_1000
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_2500_k-means-cluster#5	DHX57 ODF2L C5orf34 CFAP210 CCDC88A BRCA1 BRCA2 NR2E1	3.90e-05	831	34	8	Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_2500_K5
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000_k-means-cluster#2	ODF2L CCDC88A BRCA1 BRCA2 FGD6	1.28e-04	311	34	5	Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000_K2
CoexpressionAtlas	dev gonad_e11.5_M_PrimGermCell_Oct_k-means-cluster#1_top-relative-expression-ranked_500	BRCA1 DSP ANLN	1.75e-04	68	34	3	gudmap_dev gonad_e11.5_M_PrimGermCell_Oct_k1_500
CoexpressionAtlas	dev gonad_e12.5_F_GermCellOvary_Oct_k-means-cluster#2_top-relative-expression-ranked_500	BRCA2 BRDT FGD6	1.75e-04	68	34	3	gudmap_dev gonad_e12.5_F_GermCellOvary_Oct_k2_500
CoexpressionAtlas	FacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_2500_k-means-cluster#1	DHX57 C5orf34 CFAP210 CCDC88A BRCA1 BRCA2 NIN	1.98e-04	780	34	7	Facebase_RNAseq_e10.5_Lateral Nasal Eminence_2500_K1
CoexpressionAtlas	kidney_P4_CapMesRenVes_Crym_top-relative-expression-ranked_1000	NFE2L3 MYH9 MSI1 ITGA1 BRCA1 DSP NIN	2.03e-04	783	34	7	gudmap_kidney_P4_CapMesRenVes_Crym_1000
CoexpressionAtlas	DevelopingGonad_P2_ovary_emap-30224_k-means-cluster#2_top-relative-expression-ranked_200	MORC1 BRDT	2.24e-04	14	34	2	gudmap_developingGonad_P2_ovary_200_k2
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_500_k-means-cluster#3	CFAP210 BRCA1 BRCA2 FGD6	2.43e-04	192	34	4	Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_500_K3
CoexpressionAtlas	dev gonad_e13.5_F_MeioticGermCell_Oct_top-relative-expression-ranked_1000	DIAPH3 BRCA1 BRCA2 BRDT DSP FGD6 ANLN	2.70e-04	820	34	7	gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_1000
CoexpressionAtlas	dev gonad_e11.5_M_PrimGermCell_Oct_top-relative-expression-ranked_500	MORC1 BRCA1 BRCA2 DSP ANLN	3.09e-04	376	34	5	gudmap_dev gonad_e11.5_M_PrimGermCell_Oct_500
CoexpressionAtlas	dev gonad_e13.5_F_MeioticGermCell_Oct_top-relative-expression-ranked_500	BRCA1 BRCA2 BRDT FGD6 ANLN	3.45e-04	385	34	5	gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_500
CoexpressionAtlas	dev gonad_e11.5_F_PrimGermCell_Oct_top-relative-expression-ranked_500	MORC1 BRCA1 BRCA2 DSP ANLN	3.49e-04	386	34	5	gudmap_dev gonad_e11.5_F_PrimGermCell_Oct_500
CoexpressionAtlas	dev gonad_e12.5_M_GermCellTestis_Oct_top-relative-expression-ranked_500	MORC1 BRCA1 BRCA2 BRDT ANLN	3.53e-04	387	34	5	gudmap_dev gonad_e12.5_M_GermCellTestis_Oct_500
CoexpressionAtlas	PP_GMP_top-relative-expression-ranked_2500_k-means-cluster#5	C5orf34 TAOK3 MSH5 BRCA1 BRCA2 TGFBRAP1 PMFBP1 NIN	4.34e-04	1177	34	8	PP_GMP_2500_K5
CoexpressionAtlas	alpha beta T cells, T.8Eff.Sp.OT1.d5.VSVOva, CD8+ CD45.1+, Spleen, avg-3	ITGA1 DIAPH3 BRCA1 BRCA2 ANLN	4.59e-04	410	34	5	GSM538387_500
CoexpressionAtlas	DevelopingGonad_e16.5_testes_emap-8444_k-means-cluster#1_top-relative-expression-ranked_100	MORC1 BRDT	4.64e-04	20	34	2	gudmap_developingGonad_e16.5_testes_100_k1
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_500_k-means-cluster#5	CFAP210 BRCA1 BRCA2 NR2E1	4.98e-04	232	34	4	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_500_K5
CoexpressionAtlas	gamma delta T cells, Tgd.vg3+24alo.e17.Th, TCRd+ Vg3+ CD24-, Fetal Thymus, avg-3	DIAPH3 BRCA1 DSP ANLN PLCE1	5.07e-04	419	34	5	GSM476664_500
CoexpressionAtlas	DevelopingGonad_e14.5_ testes_emap-6710_k-means-cluster#1_top-relative-expression-ranked_100	MORC1 BRDT	5.13e-04	21	34	2	gudmap_developingGonad_e14.5_ testes_100_k1
CoexpressionAtlas	dev gonad_e12.5_F_GermCellOvary_Oct_k-means-cluster#3_top-relative-expression-ranked_500	BRCA1 DSP ANLN	7.99e-04	114	34	3	gudmap_dev gonad_e12.5_F_GermCellOvary_Oct_k3_500
CoexpressionAtlas	dev gonad_e12.5_F_GermCellOvary_Oct_k-means-cluster#2_top-relative-expression-ranked_1000	BRCA2 BRDT FGD6	8.19e-04	115	34	3	gudmap_dev gonad_e12.5_F_GermCellOvary_Oct_k2_1000
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000	ODF2L CFAP210 CCDC88A BRCA1 BRCA2 FGD6 NR2E1	8.30e-04	989	34	7	Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000
CoexpressionAtlas	DevelopingGonad_e14.5_ testes_emap-6710_k-means-cluster#1_top-relative-expression-ranked_200	MORC1 BRDT	9.83e-04	29	34	2	gudmap_developingGonad_e14.5_ testes_200_k1
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	C5orf34 ITGA1 DIAPH3 BRCA2 ANLN AKNAD1	5.82e-09	171	37	6	b92963f9f247d2e5e2e6c51c6dbf70e527cd2f55
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	C5orf34 ITGA1 DIAPH3 BRCA2 ANLN AKNAD1	5.82e-09	171	37	6	b0373ed8283ee1792b6a490bff93906546978593
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW19-Stem_cells-Stem_cells\|GW19 / Sample Type, Dataset, Time_group, and Cell type.	C5orf34 CFAP210 DIAPH3 BRCA1 ANLN NR2E1	1.40e-08	198	37	6	50f236ab7ef6f00721f6cd714e3eee183077beeb
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW19-Stem_cells\|GW19 / Sample Type, Dataset, Time_group, and Cell type.	C5orf34 CFAP210 DIAPH3 BRCA1 ANLN NR2E1	1.40e-08	198	37	6	dc0c6189ff9dd76675f63acf1cbc7dda60e75f3f
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW19-Stem_cells\|GW19 / Sample Type, Dataset, Time_group, and Cell type.	C5orf34 DIAPH3 BRCA1 BRCA2 ANLN NR2E1	1.48e-08	200	37	6	31dd81df9aa754a1e69b905bf9b8ce73ff8175aa
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW19-Stem_cells-Neuroepithelial_cell\|GW19 / Sample Type, Dataset, Time_group, and Cell type.	C5orf34 DIAPH3 BRCA1 BRCA2 ANLN NR2E1	1.48e-08	200	37	6	54174a485a82480726fa06efa6e050ddea77cb3c
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling-Cycling_Connecting_Tubule_Cell_S-high\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DIAPH3 BRCA1 BRCA2 SMCO2 ANLN	2.63e-07	167	37	5	108ae6221c6edc63c0ec42c42471b3a15a594043
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	C5orf34 DIAPH3 BRCA1 BRCA2 ANLN	3.22e-07	174	37	5	84da9faff088d05233183b425385beb054c92d1b
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	C5orf34 DIAPH3 BRCA1 BRCA2 ANLN	3.22e-07	174	37	5	dbb4e1a6c3319ce40f81bfd2d1745a88a2cc412e
ToppCell	Dividing_Macrophages-IPF_02\|World / lung cells shred on cell class, cell subclass, sample id	C5orf34 DIAPH3 BRCA1 BRCA2 ANLN	3.60e-07	178	37	5	1893fadac2ec3d5de0a641e57b7b2f962012a9ba
ToppCell	10x_3'_v3-spleen_(10x_3'_v3)-lymphocytic-T_lymphocytic-CD8-positive,_alpha-beta_T_cell\|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	DIAPH3 BRCA1 BRCA2 SMCO2 ANLN	4.36e-07	185	37	5	9d424a8608b339dd6129c58d87626678d4ec4af7
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	C5orf34 DIAPH3 BRCA1 BRCA2 ANLN	4.60e-07	187	37	5	e41e39fd3791acf8ae5376cc5061e196d96868ae
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	C5orf34 DIAPH3 BRCA1 BRCA2 ANLN	4.60e-07	187	37	5	cefa211ef224e803ea9467882e2ca74d0b1492f1
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	C5orf34 DIAPH3 BRCA1 BRCA2 ANLN	4.60e-07	187	37	5	057569c9437219ecc396aa6e673b1178a2273837
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FZD10 DIAPH3 BRCA1 BRCA2 ANLN	4.98e-07	190	37	5	31de1727822e9818652946dfb962daee77ffad68
ToppCell	3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal-Deuterosomal_L.0.3.4.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ODF2L BRCA1 BRCA2 ANLN PLCE1	4.98e-07	190	37	5	0adb24dafa077156bbc73a8d8cbf3d9eeb6e08df
ToppCell	3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ODF2L BRCA1 BRCA2 ANLN PLCE1	4.98e-07	190	37	5	05455775845f4ded5c27e7b83242078d23162aaf
ToppCell	Dividing_Macrophages-HP_01\|World / lung cells shred on cell class, cell subclass, sample id	SCN10A DIAPH3 BRCA1 BRCA2 ANLN	5.11e-07	191	37	5	3e567ed6b5fefafa7f460e49d25d60bb52a0a6c8
ToppCell	3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_proliferating-\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CCDC88A DIAPH3 BRCA1 BRCA2 ANLN	5.38e-07	193	37	5	e45ce9cf8421512b57f157c24b64793b47b4ba4b
ToppCell	PSB-critical-LOC-Epithelial-FOXN4+\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	NFE2L3 C5orf34 BRCA2 ANLN PLCE1	5.38e-07	193	37	5	b7d9c5bed524423e92f01496a9f8fad11b33a3f7
ToppCell	human_hepatoblastoma-Tumor_cells-T1\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	C5orf34 DIAPH3 BRCA1 BRCA2 ANLN	5.38e-07	193	37	5	4b9fa2a4424f8abe63fa7bee78db93dda04ab15f
ToppCell	5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_proliferating-Alveolar_macrophage_proliferating_L.1.0.7.3\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CCDC88A DIAPH3 BRCA1 BRCA2 ANLN	5.52e-07	194	37	5	e5b81a8e52259a54a911c1c2ac932c98c988318d
ToppCell	5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_proliferating\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CCDC88A DIAPH3 BRCA1 BRCA2 ANLN	5.95e-07	197	37	5	2a89a724e8c15a5bb167fdad7eed31444d8c3d68
ToppCell	3'_v3-bone_marrow-Hematopoietic_progenitors-Cycling_pre-Myeloid-1\|bone_marrow / Manually curated celltypes from each tissue	CCDC88A DIAPH3 BRCA1 BRCA2 ANLN	6.10e-07	198	37	5	5c92687b853ebb00960adbef6552f9d460bc6886
ToppCell	VE-cycling\|VE / Condition, Cell_class and T cell subcluster	ITGA1 DIAPH3 BRCA1 BRCA2 ANLN	6.25e-07	199	37	5	47c47ebc318a0b98841ca2656837bbd068899559
ToppCell	VE-cycling-\|VE / Condition, Cell_class and T cell subcluster	ITGA1 DIAPH3 BRCA1 BRCA2 ANLN	6.25e-07	199	37	5	c0a67149a19b65b3069dbc5261d81f658e6e39a2
ToppCell	Transverse-B_cell-B_cell_cycling\|B_cell / Region, Cell class and subclass	C5orf34 DIAPH3 BRCA1 FGD6 ANLN	6.25e-07	199	37	5	170ae68963d31f3b821b6f0e8f0c039bea0bc981
ToppCell	LPS_IL1RA_TNF-Endothelial-Endothelial-FOXM1\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	CCDC88A DIAPH3 BRCA1 BRCA2 ANLN	6.41e-07	200	37	5	4cfe08878a6981bf7b3567f9e82192d8f060ddde
ToppCell	distal-Hematologic-Proliferating_Macrophage-3\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	C5orf34 DIAPH3 BRCA1 BRCA2 ANLN	6.41e-07	200	37	5	9c03a8da12d29618f72c429836c1d1bd84a78b12
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-2m-Stem_cells-Neuroepithelial_cell\|2m / Sample Type, Dataset, Time_group, and Cell type.	DIAPH3 BRCA1 BRCA2 ANLN NR2E1	6.41e-07	200	37	5	0d9b8d51a7630e70e60c76c763ff82df4c559152
ToppCell	3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_proliferating\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CCDC88A DIAPH3 BRCA1 BRCA2 ANLN	6.41e-07	200	37	5	5e1b38e2aa8901bfb2623249f7b6302e97d56ace
ToppCell	Control_saline-Endothelial-Endothelial-FOXM1\|Control_saline / Treatment groups by lineage, cell group, cell type	CCDC88A DIAPH3 BRCA1 BRCA2 ANLN	6.41e-07	200	37	5	9bbc7b5561151f6ff65f40b3226271def732e5d9
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_alveolar-Dividing_AT2\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	C5orf34 DIAPH3 BRCA1 BRCA2 ANLN	6.41e-07	200	37	5	af3dc76b4507bf4edd265169f5dfbbb8a19eb394
ToppCell	Transverse-(2)_B_cell-(24)_B_cell_cycling\|Transverse / shred on region, Cell_type, and subtype	MTRF1 DIAPH3 BRCA1 FGD6 ANLN	6.41e-07	200	37	5	e3f9736227151f23f0e331eec0a7a15ce464b517
ToppCell	Biopsy_IPF-Immune-Proliferating_Macrophages\|Biopsy_IPF / Sample group, Lineage and Cell type	CCDC88A DIAPH3 BRCA1 BRCA2 ANLN	6.41e-07	200	37	5	8abb2c25422717e994468ac02d8260344341467f
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-2m-Stem_cells\|2m / Sample Type, Dataset, Time_group, and Cell type.	DIAPH3 BRCA1 BRCA2 ANLN NR2E1	6.41e-07	200	37	5	0675f580ccef705875854247bbfd4ee2bcf126a1
ToppCell	Transverse-B_cell-B_cell_cycling\|Transverse / Region, Cell class and subclass	MTRF1 DIAPH3 BRCA1 FGD6 ANLN	6.41e-07	200	37	5	0e270f8019d9f22068ca426d661937262a5cd331
ToppCell	LPS-IL1RA+antiTNF-Unknown-Endothelial-Pericyte_2\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DIAPH3 BRCA1 ANLN AKNAD1	5.32e-06	139	37	4	2fb51abb3ce88c21726c026d6365b2582e2e79f6
ToppCell	Dividing_Macrophages-Donor_01\|World / lung cells shred on cell class, cell subclass, sample id	C5orf34 DIAPH3 BRCA2 ANLN	7.58e-06	152	37	4	e39cfc346b35235546b303e7d73e4d9d7120a5fb
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DIAPH3 BRCA2 SMCO2 ANLN	8.40e-06	156	37	4	b3f10cd044f24807576e7d56e51df7064dbf6c50
ToppCell	NS-moderate-d_07-13-Epithelial-FOXN4+\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	C5orf34 BRCA2 ANLN PLCE1	8.62e-06	157	37	4	410c9d74a2085179cfb39853cb6d330fa98c9c1b
ToppCell	3'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	C5orf34 DIAPH3 ANLN NR2E1	9.51e-06	161	37	4	2165897924c790fec43502283f1df221c56c1e9f
ToppCell	LPS-antiTNF-Endothelial-Endothelial-FOXM1\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DIAPH3 BRCA1 BRCA2 ANLN	9.99e-06	163	37	4	5285318c52aa31c9b22dc2ffff078e32e408604d
ToppCell	390C-Myeloid-Dendritic-cDC_proliferating_2\|390C / Donor, Lineage, Cell class and subclass (all cells)	CFAP210 DIAPH3 ANLN PMFBP1	1.02e-05	164	37	4	ad508f53009efdd1dae7abcdb5431387f3f7e7b2
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DIAPH3 BRCA1 BRCA2 ANLN	1.05e-05	165	37	4	88681101d7cf60b99b8ace5d8c0944323b937306
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DIAPH3 BRCA1 BRCA2 ANLN	1.07e-05	166	37	4	2642544070564debe2deb2938d2c33997bf5ef02
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DIAPH3 BRCA1 BRCA2 ANLN	1.10e-05	167	37	4	50c29ea660bf07b890e4ac1a1985d0761d863dee
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DIAPH3 BRCA1 BRCA2 ANLN	1.13e-05	168	37	4	d35944fd9fea9934ce1e76b2b35d48e2300cca61
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DIAPH3 BRCA1 BRCA2 ANLN	1.15e-05	169	37	4	121768fc51fc3441ec725346a1bbe29e21d05971
ToppCell	Dividing_Macrophages-Donor_08\|World / lung cells shred on cell class, cell subclass, sample id	DIAPH3 BRCA2 ANLN PMFBP1	1.15e-05	169	37	4	eb0c993ef2eea73bc4881182520922ce9ae9368f
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DIAPH3 BRCA1 BRCA2 ANLN	1.15e-05	169	37	4	b253a4a50c06d36228fcd5d856c57202cbac158f
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DIAPH3 BRCA1 BRCA2 ANLN	1.15e-05	169	37	4	0bc8ef341ce307b19018d4ac8de0a4d04254209d
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling-Cycling_Distal_Convoluted_Tubule_Cell_S-high\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DIAPH3 BRCA1 BRCA2 ANLN	1.15e-05	169	37	4	e7514956b2e4298222ec443f98b2f5289451786e
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DIAPH3 BRCA1 BRCA2 ANLN	1.26e-05	173	37	4	a25459b8140b0dbcb73e3b4cc1407b679229f25c
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DIAPH3 BRCA1 BRCA2 ANLN	1.29e-05	174	37	4	c26eac176e9b0cba385630fdc60e0314a4e4caac
ToppCell	Dividing_Macrophages-IPF_03\|World / lung cells shred on cell class, cell subclass, sample id	DIAPH3 BRCA1 BRCA2 ANLN	1.32e-05	175	37	4	0a8bf455babb3271aa00642199fb58b0b02dc3ac
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling-Cycling_Distal_Convoluted_Tubule_Cell_G2M\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	C5orf34 DIAPH3 BRCA2 ANLN	1.32e-05	175	37	4	876cea684faf42ff3eb4623ad6d7a1fb1276ee02
ToppCell	NS-critical-d_16-33-Epithelial-FOXN4+\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	BRCA1 BRCA2 ANLN PLCE1	1.35e-05	176	37	4	7cf1a06ceee1ec06532f44c729c31b4d58e5ea49
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DIAPH3 BRCA1 BRCA2 ANLN	1.38e-05	177	37	4	f925a15d2162d166a5b60edac3517c6b2d6cfbea
ToppCell	PND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_G2M\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DIAPH3 BRDT ANLN AKNAD1	1.38e-05	177	37	4	4197cf2b1e743230c821f422836fa5991b155a52
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DIAPH3 BRCA1 BRCA2 ANLN	1.44e-05	179	37	4	88d44b04eb5c079531db663ed98ddb20b60feb9a
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DIAPH3 BRCA1 BRCA2 ANLN	1.44e-05	179	37	4	80112c686a8f85ad5e3cda6e3f3d3d51cf688092
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CFAP210 DIAPH3 ANLN PLCE1	1.48e-05	180	37	4	0c146e80d55d18b6988dd21b1da635801bd3140c
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	C5orf34 DIAPH3 BRCA2 ANLN	1.48e-05	180	37	4	401df9cddcbca1eb8f0d2687bcacd98e95dc1493
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CFAP210 DIAPH3 ANLN PLCE1	1.48e-05	180	37	4	e9af22beae2f3c7fe213b4e19df84abfd2453433
ToppCell	LPS-IL1RA-Endothelial-Endothelial-FOXM1\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DIAPH3 BRCA1 BRCA2 ANLN	1.48e-05	180	37	4	334e2b1f6eb7d4ece20b1c7b02107863f913237f
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DIAPH3 BRCA1 BRCA2 ANLN	1.48e-05	180	37	4	f8a15c13d85c1bbbf86ce49bb6f86c368ddf22df
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal-Deuterosomal_L.0.3.4.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CFAP210 DIAPH3 ANLN PLCE1	1.48e-05	180	37	4	11455ba704ac73f69b474845136cfecec6a88349
ToppCell	5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_proliferating-Alveolar_macrophage_proliferating_L.1.0.7.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	C5orf34 DIAPH3 BRCA2 ANLN	1.51e-05	181	37	4	73b1b59810f60e3e39ca1d5073a5a0d4f5377e6e
ToppCell	10x5'-bone_marrow-Hematopoietic_progenitors-Cycling_pre-Myeloid-1\|bone_marrow / Manually curated celltypes from each tissue	CCDC88A BRCA1 BRCA2 ANLN	1.51e-05	181	37	4	ccd0ed30cea3fb41d34f28b3e8d80a94493bef3c
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling-Cycling_Connecting_Tubule_Cell_G2M\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	C5orf34 DIAPH3 BRCA2 ANLN	1.54e-05	182	37	4	336cd05e46a741185ce3c59ee67a4b07fa6a5101
ToppCell	10x5'-Liver-Lymphocytic_T_CD4/8-lo-Cycling_T\|Liver / Manually curated celltypes from each tissue	DIAPH3 BRCA1 BRCA2 ANLN	1.54e-05	182	37	4	81557cdc88777f3bd4e1dd18a760b08fc29122ef
ToppCell	TCGA-Liver-Primary_Tumor-Hepatocellular_Carcinoma-Hepatocellular_Carcinoma-5\|TCGA-Liver / Sample_Type by Project: Shred V9	C5orf34 BRCA1 BRCA2 ANLN	1.57e-05	183	37	4	f604a8b62c7088fad8365dbf8d910fc980bd3ba8
ToppCell	IIF-Lymphocyte-T_NK-T_NK_proliferative\|IIF / Disease, Lineage and Cell Type	DIAPH3 BRCA1 BRCA2 ANLN	1.61e-05	184	37	4	ab8b45ce40e8c5f66e5c23332a591b4f9cba4ce1
ToppCell	Dividing_Macrophages-IPF_01\|World / lung cells shred on cell class, cell subclass, sample id	DIAPH3 BRCA1 BRCA2 ANLN	1.61e-05	184	37	4	f15ce786d25c6546804a6d1efcc2ad645f2ef54e
ToppCell	Control-T_cells-Cycling_NK/T_cells\|Control / group, cell type (main and fine annotations)	DIAPH3 BRCA1 BRCA2 ANLN	1.64e-05	185	37	4	9766216b41ee62bbac4caa25cb98ec5627a24075
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DIAPH3 BRCA1 BRCA2 ANLN	1.64e-05	185	37	4	30e041d6f6e310d64809e9d6d93cd30052972f3b
ToppCell	droplet-Spleen-nan-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DIAPH3 BRCA2 SMCO2 ANLN	1.71e-05	187	37	4	c81d11d9fdc22dc39222f62c2888025c2e8c3e65
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DIAPH3 BRCA1 BRCA2 ANLN	1.71e-05	187	37	4	9351fa87b69a951af85b10bf91fe9b1cce8c0517
ToppCell	ILEUM-non-inflamed-(1)_T_cell-(1)_CD8_Trm\|(1)_T_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	ODF2L MYH9 ITGA1 NIN	1.79e-05	189	37	4	2c8a2fb76ea002bac554bc1c761ce960b5e116e1
ToppCell	Control-Endothelial-Endothelial-FOXM1\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DIAPH3 BRCA1 BRCA2 ANLN	1.79e-05	189	37	4	1e1499b062d9c647c8f38b0c4e0d871d159be5dd
ToppCell	NS-moderate-d_16-33-Epithelial-FOXN4+\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	BRCA1 BRCA2 ANLN PLCE1	1.82e-05	190	37	4	250ca4a605c1cccd77d23383e4fe6f91cf3609ba
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_proliferating_SM_(20)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	DIAPH3 BRCA1 BRCA2 ANLN	1.82e-05	190	37	4	e83fa8b711aa79a1767818474f1c193b674b1c31
ToppCell	pdx-Tumor_cells-T1\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	DIAPH3 BRCA1 BRCA2 ANLN	1.82e-05	190	37	4	d06ee5f89f1cec8db6897fe3b2a890a07cd3697b
ToppCell	3'_v3-bone_marrow-Lymphocytic_T_CD4/8-lo-Cycling_T\|bone_marrow / Manually curated celltypes from each tissue	DIAPH3 BRCA1 BRCA2 ANLN	1.86e-05	191	37	4	210a0f1a71df2508cbfc73d6868a2122338b9a1c
ToppCell	3'_v3-GI_small-bowel-Lymphocytic_T_CD4/8-lo-Cycling_T\|GI_small-bowel / Manually curated celltypes from each tissue	DIAPH3 BRCA1 BRCA2 ANLN	1.86e-05	191	37	4	e642fa7395c05fb53324c9d46bbc52f89fc9673f
ToppCell	Mild-T/NK_proliferative\|World / Disease group and Cell class	DIAPH3 BRCA1 BRCA2 ANLN	1.86e-05	191	37	4	9dba5526fd5ea8065ad305feb2ee562335f887c6
ToppCell	3'-Distal_airway-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_proliferating-Alveolar_macrophage_proliferating_L.1.0.7.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DIAPH3 BRCA1 BRCA2 ANLN	1.86e-05	191	37	4	b85a0978dc1e8af4f49423f56dcfd52efce09ed1
ToppCell	Control-Lymphoid-Proliferating_CD4_T_cells\|Control / Condition, Lineage and Cell class	DIAPH3 BRCA1 BRCA2 ANLN	1.94e-05	193	37	4	33d409d6ed1c606337248587ad997ac5f67f081d
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_myocytic-mes_proliferating_SM_(20)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	DIAPH3 BRCA1 BRCA2 ANLN	1.94e-05	193	37	4	516ea2c12bdc7a5dc676159d627e36f6abe13ef0
ToppCell	PBMC-Control-Lymphocyte-T/NK-Other_T-T/NK_proliferative\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	DIAPH3 BRCA1 BRCA2 ANLN	1.98e-05	194	37	4	f39a471293ecc5c5967b00e772b8f48ebc9affbe
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Scavenging_endothelial-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	FRY MYH9 ITGA1 DSP	1.98e-05	194	37	4	ea5e1bc8d9e27cabfe1fb833ca47ec0893593b12
ToppCell	PCW_07-8.5\|World / Celltypes from embryonic and fetal-stage human lung	DIAPH3 BRCA2 FGD6 NIN	1.98e-05	194	37	4	5759c83308df017f1faae248e9b85388e25254f0
ToppCell	PBMC-Control-Lymphocyte-T/NK-Other_T-T/NK_proliferative-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	DIAPH3 BRCA1 BRCA2 ANLN	1.98e-05	194	37	4	a75ecd0b0a928d4646602f7d16a645f6b3df3af5
ToppCell	3'_v3-Lung-Myeloid_Mac-Cycling_Myeloid-Mac\|Lung / Manually curated celltypes from each tissue	DIAPH3 BRCA1 BRCA2 ANLN	1.98e-05	194	37	4	a8ae49157ca3f9e8b3f1750a995aee012dc859b6
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DIAPH3 BRCA1 BRCA2 ANLN	1.98e-05	194	37	4	4c1d13d8cb6fb424655c67755ee6dbaf59d6b418
ToppCell	PBMC-Control-Lymphocyte-T/NK-Other_T-T/NK_proliferative-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	DIAPH3 BRCA1 BRCA2 ANLN	1.98e-05	194	37	4	17744fd6645cf5a447a01a83f07e8d305c2bcd9c
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DIAPH3 BRCA1 BRCA2 ANLN	1.98e-05	194	37	4	1a2090e997c70433d07f56bf7cb0a50c4151118c
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_cycling-mes_proliferating3_(7)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	DIAPH3 BRCA1 BRCA2 ANLN	1.98e-05	194	37	4	f9070035553bc68106a9e0bdf4b507715a138aba
ToppCell	3'_v3-blood-Lymphocytic_NK-Cycling_NK\|blood / Manually curated celltypes from each tissue	DIAPH3 BRCA1 BRCA2 ANLN	1.98e-05	194	37	4	bf9734abaad603ade2a6a6940918aaf1e1c4e2cd
Drug	veliparib	CYP2C19 BRCA1 BRCA2	5.96e-06	22	37	3	ctd:C521013
Drug	Fenoprofen calcium salt dihydrate [53746-45-5]; Up 200; 7.2uM; PC3; HT_HG-U133A	SCN10A FZD10 FRY NR2E3 PMFBP1	1.73e-05	200	37	5	3714_UP
Drug	Lucanthone	C5orf34 DIAPH3 BRCA1 BRCA2 ANLN	2.28e-05	212	37	5	ctd:D008154
Drug	limonene	CYP2C19 ANLN GLG1	2.95e-05	37	37	3	CID000022311
Drug	EHDA	BRCA1 BRCA2	3.84e-05	6	37	2	CID006438592
Drug	hydroxyoctanoate	BRCA1 BRCA2 DSP	4.04e-05	41	37	3	CID000094180
Disease	ductal carcinoma in situ (biomarker_via_orthology)	BRCA1 BRCA2	1.37e-06	2	35	2	DOID:0060074 (biomarker_via_orthology)
Disease	Hereditary site-specific ovarian cancer syndrome	BRCA1 BRCA2	1.37e-06	2	35	2	C4749652
Disease	Hereditary breast ovarian cancer syndrome	BRCA1 BRCA2	8.19e-06	4	35	2	cv:C0677776
Disease	hereditary breast ovarian cancer syndrome (is_implicated_in)	BRCA1 BRCA2	1.36e-05	5	35	2	DOID:5683 (is_implicated_in)
Disease	Adult only	BRCA1 BRCA2	2.04e-05	6	35	2	C3842001
Disease	intelligence, specific language impairment, dyslexia	CCDC136 PMFBP1	3.81e-05	8	35	2	EFO_0004337, EFO_0005424, EFO_1001510
Disease	Pancreatic carcinoma, familial	BRCA1 BRCA2	4.89e-05	9	35	2	C2931038
Disease	Fanconi anemia (is_implicated_in)	BRCA1 BRCA2	6.11e-05	10	35	2	DOID:13636 (is_implicated_in)
Disease	specific language impairment, dyslexia	CCDC136 PMFBP1	8.95e-05	12	35	2	EFO_0005424, EFO_1001510
Disease	Benign tumor of pancreas	BRCA1 BRCA2	1.06e-04	13	35	2	C0347284
Disease	Hereditary Breast and Ovarian Cancer Syndrome	BRCA1 BRCA2	1.23e-04	14	35	2	C0677776
Disease	Pancreatic carcinoma	BRCA1 BRCA2	2.31e-04	19	35	2	C0235974
Disease	Adenocarcinoma of prostate	BRCA1 BRCA2	2.56e-04	20	35	2	C0007112
Disease	BREAST CANCER	BRCA1 BRCA2	2.83e-04	21	35	2	114480
Disease	platelet reactivity measurement, response to clopidogrel	CYP2C19 PLCE1	3.40e-04	23	35	2	EFO_0004985, GO_1903493
Disease	low density lipoprotein cholesterol measurement, phospholipid measurement	NFE2L3 ITGA1 BRCA2	3.90e-04	120	35	3	EFO_0004611, EFO_0004639
Disease	apolipoprotein L1 measurement	MYH9 PMFBP1	4.03e-04	25	35	2	EFO_0021854
Disease	Fanconi Anemia	BRCA1 BRCA2	4.03e-04	25	35	2	C0015625
Disease	breast cancer (implicated_via_orthology)	BRCA1 BRCA2	4.03e-04	25	35	2	DOID:1612 (implicated_via_orthology)
Disease	age at menopause	FZD10 MSH5 BRCA1 TGFBRAP1	4.39e-04	302	35	4	EFO_0004704
Disease	Malignant tumor of breast	BRCA1 BRCA2	4.71e-04	27	35	2	cv:C0006142
Disease	Breast neoplasm	BRCA1 BRCA2	4.71e-04	27	35	2	cv:C1458155
Disease	Familial cancer of breast	BRCA1 BRCA2	4.71e-04	27	35	2	cv:C0346153
Disease	Hyalinosis, Segmental Glomerular	MYH9 ANLN	5.07e-04	28	35	2	C0086432
Disease	ovarian neoplasm	LRRC59 BRCA1 BRCA2	5.39e-04	134	35	3	C0919267
Disease	Miller Dieker syndrome	BRCA1 BRCA2	5.44e-04	29	35	2	C0265219
Disease	Neoplasm of uncertain or unknown behavior of ovary	BRCA1 BRCA2	5.44e-04	29	35	2	C0496920
Disease	Malignant neoplasm of ovary	LRRC59 BRCA1 BRCA2	5.75e-04	137	35	3	C1140680
Disease	Ovarian Carcinoma	BRCA1 BRCA2	5.82e-04	30	35	2	C0029925
Disease	Breast Cancer, Familial	BRCA1 BRCA2	5.82e-04	30	35	2	C0346153
Disease	NEPHROTIC SYNDROME, STEROID-RESISTANT, AUTOSOMAL RECESSIVE	ANLN PLCE1	5.82e-04	30	35	2	C1868672
Disease	breast cancer (is_implicated_in)	CYP2C19 BRCA1 BRCA2	7.48e-04	150	35	3	DOID:1612 (is_implicated_in)
Disease	Focal glomerulosclerosis	MYH9 ANLN	8.40e-04	36	35	2	C0017668
Disease	colorectal carcinoma (is_marker_for)	BRCA1 BRCA2	8.87e-04	37	35	2	DOID:0080199 (is_marker_for)
Disease	squamous cell lung carcinoma	FRY MSH5 BRCA2	9.85e-04	165	35	3	EFO_0000708
Disease	apolipoprotein B measurement	NFE2L3 ITGA1 BRCA2 PMFBP1 AKNAD1	1.05e-03	663	35	5	EFO_0004615
Disease	pulse pressure measurement	SCN10A ODF2L MSH5 ITGA1 FGD6 PLCE1 NIN	1.08e-03	1392	35	7	EFO_0005763
Disease	Neoplasm of uncertain or unknown behavior of breast	BRCA1 BRCA2	1.09e-03	41	35	2	C0496956
Disease	Breast adenocarcinoma	BRCA1 BRCA2	1.09e-03	41	35	2	C0858252

Protein segments in the cluster

Peptide	Gene	Start	Entry
NCEQITAKMEQTKNK	ANKRD30B	966	Q9BXX2
KEKVNNSNENPRKMC	BRDT	461	Q58F21
SCNEEENFANMKKKA	AGGF1	306	Q8N302
KNQHKVIQCLKALMN	DIAPH3	241	Q9NSV4
KKCLQAGMNQDAVQN	NR2E3	106	Q9Y5X4
RKKNEEQNQLVCKMN	ODF2L	616	Q9ULJ1
EQMNKKLKMCFNQIQ	MORC1	856	Q86VD1
QCKQCANKVLQHMKA	LRRC59	136	Q96AG4
KNNAFPCQVNIKQKM	ANLN	706	Q9NQW6
LQNCQNLSKDLMKEK	CCDC88A	521	Q3V6T2
KREQAQCNKAINIMK	NFE2L3	621	Q9Y4A8
QCNKAINIMKQKLHD	NFE2L3	626	Q9Y4A8
CQHLQAEKKKMQQNI	MYH9	931	P35579
FEPNKVNIQKKNCHM	ITGA1	676	P56199
FHEINNKMVECKKAQ	MSI1	171	O43347
RMNVEKAEFCNKSKQ	BRCA1	296	P38398
AAQHKCKMNNQTKTL	FZD10	476	Q9ULW2
LIQNKHQKDMNEKCA	GLG1	721	Q92896
CFLIKMEKEKQNQQS	CYP2C19	266	P33261
ENNENKSKICQTKIM	BRCA2	1876	P51587
AENGKICKQFRMKQA	DHX57	516	Q6P158
QQKACGSEIMQKKQH	DSP	1276	P15924
QGKQMCQKLKEQTDQ	AKNAD1	376	Q5T1N1
NNCLSNLKNKDPKMA	FRY	386	Q5TBA9
LKNKENEFHCQIMKS	C5orf34	191	Q96MH7
KKCLEVNMNKDAVQH	NR2E1	76	Q9Y466
PVKDLLKKNQMENCQ	MSH5	786	O43196
LKKNQMENCQTLVDK	MSH5	791	O43196
QKQHQNDLKMLAAKE	PMFBP1	826	Q8TBY8
SCKKAQENMKQRHEN	NIN	646	Q8N4C6
KLMELAKNCDNKNEQ	PLCE1	236	Q9P212
EMQIKKQFQDTCKVQ	TAOK3	716	Q9H2K8
MCKSLNKQDEKQLQE	MTRF1	136	O75570
KASQKEMGQLQMEQC	CCDC136	551	Q96JN2
IQQMAKNKFNAKQAK	CFAP210	436	Q0VFZ6
NQLTQGDQEKMAKCK	TGFBRAP1	411	Q8WUH2
NLKNKCVKNDMAVNE	SCN10A	271	Q9Y5Y9
QNVLCKQEQVDKMKL	FGD6	366	Q6ZV73
MKMDCQEQQLTKKNN	SMCO2	16	A6NFE2