Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	DNA-binding transcription factor activity, RNA polymerase II-specific	ZNF355P ZNF138 ZNF716 ZNF141 ZFAT ZBTB20 ZNF680 ZNF695 ZNF35 ZFHX4 ZNF37A ZNF337 ZNF559 ZNF423 ZNF92 ZFP1 ZNF429 ZBTB5 ZNF300 ZBTB47 KLF15 ZNF431 ZNF215 ZNF721 ZBTB41 E4F1 ZNF510 ZNF518B ZNF91 ZNF519 ZNF236 ZNF626 PRDM4 ZNF614 ZFP37 ZNF551 ZNF292	6.94e-20	1412	89	37	GO:0000981
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	ZNF355P ZNF138 ZNF716 ZNF141 ZFAT ZBTB20 ZNF680 ZNF695 ZNF35 ZFHX4 ZNF37A ZNF337 ZNF559 ZNF423 ZNF92 ZFP1 ZNF429 ZBTB5 ZNF300 KLF15 ZNF431 ZNF215 ZNF721 ZBTB41 E4F1 ZNF510 ZNF518B ZNF91 ZNF519 ZNF236 ZNF626 PRDM4 ZNF614 ZFP37 ZNF551	1.65e-17	1459	89	35	GO:0000977
GeneOntologyMolecularFunction	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ZNF355P ZNF138 ZNF716 ZNF141 ZFAT ZBTB20 ZNF680 ZNF695 ZFHX4 ZNF37A ZNF423 ZNF92 ZFP1 ZNF429 ZNF300 KLF15 ZNF431 ZNF215 ZNF721 ZBTB41 E4F1 ZNF91 ZNF519 ZNF236 ZNF626 PRDM4 ZNF551	2.44e-12	1244	89	27	GO:0000978
GeneOntologyMolecularFunction	cis-regulatory region sequence-specific DNA binding	ZNF355P ZNF138 ZNF716 ZNF141 ZFAT ZBTB20 ZNF680 ZNF695 ZFHX4 ZNF37A ZNF423 ZNF92 ZFP1 ZNF429 ZNF300 KLF15 ZNF431 ZNF215 ZNF721 ZBTB41 E4F1 ZNF91 ZNF519 ZNF236 ZNF626 PRDM4 ZNF551	4.02e-12	1271	89	27	GO:0000987
GeneOntologyMolecularFunction	DNA-binding transcription activator activity	BNC1 ZFAT ZNF695 ZNF300 KLF15 ZNF721 E4F1 ZNF91 ZNF519 PRDM4 ZNF292	4.26e-05	566	89	11	GO:0001216
GeneOntologyMolecularFunction	DNA-binding transcription activator activity, RNA polymerase II-specific	ZFAT ZNF695 ZNF300 KLF15 ZNF721 E4F1 ZNF91 ZNF519 PRDM4 ZNF292	1.94e-04	560	89	10	GO:0001228
Domain	Znf_C2H2/integrase_DNA-bd	ZXDC ZNF138 ZNF716 ZNF141 ZFAT ZBTB20 ZNF680 ZNF695 ZNF35 ZFHX4 ZNF37A ZNF337 ZNF559 ZNF423 ZNF92 ZFP64 ZFP1 ZNF429 ZBTB5 ZNF300 ZBTB47 KLF15 ZNF431 ZNF215 ZNF721 ZBTB41 E4F1 ZNF510 ZNF518B ZNF91 ZNF519 ZNF236 ZNF626 PRDM4 ZNF614 ZFP37 ZNF551 ZNF292	3.46e-31	694	88	38	IPR013087
Domain	ZINC_FINGER_C2H2_2	ZXDC BNC1 ZNF138 ZNF716 ZNF141 ZFAT ZBTB20 ZNF680 ZNF695 ZNF35 ZFHX4 ZNF37A ZNF337 ZNF559 ZNF423 ZNF92 ZFP64 ZFP1 ZNF429 ZBTB5 ZNF300 ZBTB47 KLF15 ZNF431 ZNF215 ZNF721 ZBTB41 E4F1 ZNF510 ZNF518B ZNF91 ZNF519 ZNF236 ZNF626 PRDM4 ZNF614 ZFP37 ZNF551 ZNF292	1.08e-30	775	88	39	PS50157
Domain	ZINC_FINGER_C2H2_1	ZXDC BNC1 ZNF138 ZNF716 ZNF141 ZFAT ZBTB20 ZNF680 ZNF695 ZNF35 ZFHX4 ZNF37A ZNF337 ZNF559 ZNF423 ZNF92 ZFP64 ZFP1 ZNF429 ZBTB5 ZNF300 ZBTB47 KLF15 ZNF431 ZNF215 ZNF721 ZBTB41 E4F1 ZNF510 ZNF518B ZNF91 ZNF519 ZNF236 ZNF626 PRDM4 ZNF614 ZFP37 ZNF551 ZNF292	1.20e-30	777	88	39	PS00028
Domain	Znf_C2H2-like	ZXDC BNC1 ZNF138 ZNF716 ZNF141 ZFAT ZBTB20 ZNF680 ZNF695 ZNF35 ZFHX4 ZNF37A ZNF337 ZNF559 ZNF423 ZNF92 ZFP64 ZFP1 ZNF429 ZBTB5 ZNF300 ZBTB47 KLF15 ZNF431 ZNF215 ZNF721 ZBTB41 E4F1 ZNF510 ZNF518B ZNF91 ZNF519 ZNF236 ZNF626 PRDM4 ZNF614 ZFP37 ZNF551 ZNF292	2.99e-30	796	88	39	IPR015880
Domain	-	ZXDC ZNF138 ZNF716 ZNF141 ZFAT ZBTB20 ZNF680 ZNF695 ZNF35 ZFHX4 ZNF37A ZNF337 ZNF559 ZNF423 ZNF92 ZFP64 ZFP1 ZNF429 ZBTB5 ZNF300 ZBTB47 KLF15 ZNF431 ZNF215 ZNF721 ZBTB41 E4F1 ZNF510 ZNF91 ZNF519 ZNF236 ZNF626 PRDM4 ZNF614 ZFP37 ZNF551 ZNF292	3.20e-30	679	88	37	3.30.160.60
Domain	Znf_C2H2	ZXDC BNC1 ZNF138 ZNF716 ZNF141 ZFAT ZBTB20 ZNF680 ZNF695 ZNF35 ZFHX4 ZNF37A ZNF337 ZNF559 ZNF423 ZNF92 ZFP64 ZFP1 ZNF429 ZBTB5 ZNF300 ZBTB47 KLF15 ZNF431 ZNF215 ZNF721 ZBTB41 E4F1 ZNF510 ZNF518B ZNF91 ZNF519 ZNF236 ZNF626 PRDM4 ZNF614 ZFP37 ZNF551 ZNF292	4.57e-30	805	88	39	IPR007087
Domain	ZnF_C2H2	ZXDC BNC1 ZNF138 ZNF716 ZNF141 ZFAT ZBTB20 ZNF680 ZNF695 ZNF35 ZFHX4 ZNF37A ZNF337 ZNF559 ZNF423 ZNF92 ZFP64 ZFP1 ZNF429 ZBTB5 ZNF300 ZBTB47 KLF15 ZNF431 ZNF215 ZNF721 ZBTB41 E4F1 ZNF510 ZNF518B ZNF91 ZNF519 ZNF236 ZNF626 PRDM4 ZNF614 ZFP37 ZNF551 ZNF292	5.26e-30	808	88	39	SM00355
Domain	zf-C2H2	BNC1 ZNF138 ZNF716 ZNF141 ZFAT ZBTB20 ZNF680 ZNF695 ZNF35 ZFHX4 ZNF37A ZNF337 ZNF559 ZNF423 ZNF92 ZFP64 ZFP1 ZNF429 ZBTB5 ZNF300 ZBTB47 KLF15 ZNF431 ZNF215 ZNF721 ZBTB41 E4F1 ZNF510 ZNF91 ZNF519 ZNF236 ZNF626 PRDM4 ZNF614 ZFP37 ZNF551 ZNF292	6.69e-30	693	88	37	PF00096
Domain	KRAB	ZNF716 ZNF141 ZNF680 ZNF695 ZNF37A ZNF337 ZNF559 ZNF92 ZFP1 ZNF429 ZNF300 ZNF431 ZNF215 ZNF510 ZNF91 ZNF519 ZNF626 ZNF614 ZFP37 ZNF551	2.48e-16	358	88	20	PS50805
Domain	KRAB	ZNF716 ZNF141 ZNF680 ZNF695 ZNF37A ZNF337 ZNF559 ZNF92 ZFP1 ZNF429 ZNF300 ZNF431 ZNF215 ZNF510 ZNF91 ZNF519 ZNF626 ZNF614 ZFP37 ZNF551	2.48e-16	358	88	20	PF01352
Domain	KRAB	ZNF716 ZNF141 ZNF680 ZNF695 ZNF37A ZNF337 ZNF559 ZNF92 ZFP1 ZNF429 ZNF300 ZNF431 ZNF215 ZNF510 ZNF91 ZNF519 ZNF626 ZNF614 ZFP37 ZNF551	4.44e-16	369	88	20	SM00349
Domain	KRAB	ZNF716 ZNF141 ZNF680 ZNF695 ZNF37A ZNF337 ZNF559 ZNF92 ZFP1 ZNF429 ZNF300 ZNF431 ZNF215 ZNF510 ZNF91 ZNF519 ZNF626 ZNF614 ZFP37 ZNF551	4.68e-16	370	88	20	IPR001909
Domain	zf-C2H2_6	ZNF141 ZNF680 ZNF695 ZNF423 ZNF92 ZFP64 ZNF429 ZBTB47 ZNF431 ZNF721 ZBTB41 E4F1 ZNF91 ZNF236 ZNF626 ZFP37 ZNF551	9.28e-14	314	88	17	PF13912
Domain	BTB	KLHL11 ZBTB20 RHOBTB3 ZBTB5 ZBTB47 ZBTB41	3.59e-05	131	88	6	PF00651
Domain	BTB	KLHL11 ZBTB20 RHOBTB3 ZBTB5 ZBTB47 ZBTB41	1.09e-04	160	88	6	PS50097
Domain	BTB	KLHL11 ZBTB20 RHOBTB3 ZBTB5 ZBTB47 ZBTB41	2.08e-04	180	88	6	SM00225
Domain	BTB/POZ_dom	KLHL11 ZBTB20 RHOBTB3 ZBTB5 ZBTB47 ZBTB41	2.41e-04	185	88	6	IPR000210
Domain	SKP1/BTB/POZ	KLHL11 ZBTB20 RHOBTB3 ZBTB5 ZBTB47 ZBTB41	2.70e-04	189	88	6	IPR011333
Domain	VPS9	RIN3 RABGEF1	6.03e-04	8	88	2	SM00167
Domain	VPS9	RIN3 RABGEF1	9.64e-04	10	88	2	PS51205
Domain	VPS9	RIN3 RABGEF1	9.64e-04	10	88	2	PF02204
Domain	VPS9	RIN3 RABGEF1	9.64e-04	10	88	2	IPR003123
Domain	Quinoprotein_ADH-like_supfam	DMXL2 WDR1 WDR17	2.00e-03	53	88	3	IPR011047
Domain	N2O_reductase_N	WDR1 WDR17	2.21e-03	15	88	2	IPR011045
Domain	G-protein_beta_WD-40_rep	DCAF11 WDR1 WDR17	7.56e-03	85	88	3	IPR020472
Domain	WD40	DMXL2 DCAF11 WDR1 HERC1 WDR17	7.60e-03	259	88	5	PF00400
Domain	WD40	DMXL2 DCAF11 WDR1 HERC1 WDR17	8.73e-03	268	88	5	SM00320
Domain	WD40_repeat	DMXL2 DCAF11 WDR1 HERC1 WDR17	9.27e-03	272	88	5	IPR001680
Domain	RA	RIN3 GRB10	9.34e-03	31	88	2	SM00314
Domain	WD_REPEATS_1	DMXL2 DCAF11 WDR1 HERC1 WDR17	1.01e-02	278	88	5	PS00678
Domain	WD_REPEATS_2	DMXL2 DCAF11 WDR1 HERC1 WDR17	1.03e-02	279	88	5	PS50082
Domain	WD_REPEATS_REGION	DMXL2 DCAF11 WDR1 HERC1 WDR17	1.03e-02	279	88	5	PS50294
Pathway	REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION	ZNF138 ZNF716 ZNF141 ZNF680 ZNF37A ZNF337 ZNF559 ZNF92 ZFP1 ZNF429 ZNF300 ZNF431 ZNF215 ZNF721 ZNF510 ZNF519 ZNF626 ZNF614 ZFP37 ZNF551	7.57e-07	1387	61	20	M734
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	ZXDC ZNF716 ZBTB20 ZNF423 RHOBTB3 ZFP64 ZNF429 ZBTB5 ZNF300 KLF15 ZNF721 ZBTB41 ZNF91 ZNF236 ZNF626 PRDM4 ZFP37 DOP1B ZNF292	2.24e-13	808	90	19	20412781
Pubmed	Regulator of sex-limitation (Rsl) encodes a pair of KRAB zinc-finger genes that control sexually dimorphic liver gene expression.	ZNF355P ZNF716 ZNF695 ZNF429 ZNF721 ZNF91 ZNF626	9.13e-13	29	90	7	14563677
Pubmed	Rapid and efficient cloning of cDNAs encoding Krüppel-like zinc finger proteins by degenerate PCR.	ZNF355P ZNF695 ZNF429 ZNF300 ZNF721 ZNF91	3.24e-09	49	90	6	9630514
Pubmed	Expansion and diversification of KRAB zinc-finger genes within a cluster including Regulator of sex-limitation 1 and 2.	ZNF355P ZNF429 ZNF721 ZNF91	5.60e-08	15	90	4	15885501
Pubmed	Acetylation-Mimic Mutation of TRIM28-Lys304 to Gln Attenuates the Interaction with KRAB-Zinc-Finger Proteins and Affects Gene Expression in Leukemic K562 Cells.	ZNF680 ZNF92 ZFP1 ZNF721 ZNF91 ZNF626 ZNF614	4.78e-07	181	90	7	37372979
Pubmed	GSAP regulates lipid homeostasis and mitochondrial function associated with Alzheimer's disease.	ZBTB20 GSAP	6.62e-06	2	90	2	34156424
Pubmed	An atlas of combinatorial transcriptional regulation in mouse and man.	DENND4A ZBTB20 ZNF35 ZNF92 ZFP64 ZBTB5 E4F1 ZNF519 ZNF236 PRDM4 ZNF292	1.67e-05	877	90	11	20211142
Pubmed	Regulation of the cysteine desulfurase Nfs1 and the scaffold protein IscU in macrophages stimulated with interferon-gamma and lipopolysaccharide.	NFS1 NOS2	1.98e-05	3	90	2	17603005
Pubmed	A census of human transcription factors: function, expression and evolution.	BNC1 ZNF35 ZFHX4 ZNF37A KLF15 ZNF215 E4F1 ZNF91 ZNF236 PRDM4 ZNF551	2.30e-05	908	90	11	19274049
Pubmed	CCR6 ligands inhibit HIV by inducing APOBEC3G.	APOBEC3G CCL20	3.96e-05	4	90	2	20023216
Pubmed	Multiple genes encoding zinc finger domains are expressed in human T cells.	ZNF37A ZFP1 ZNF551	7.15e-05	31	90	3	2288909
Pubmed	The KRAB-zinc-finger protein ZFP708 mediates epigenetic repression at RMER19B retrotransposons.	ZNF355P ZNF429	9.87e-05	6	90	2	30846446
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	DMXL2 TTC28 ZNF423 RHOBTB3 ZNF92 ZBTB5 ZBTB47 PRDM4 WDR17 TRIM59 DOP1B ZNF292	1.18e-04	1285	90	12	35914814
Pubmed	WD40-repeat 47, a microtubule-associated protein, is essential for brain development and autophagy.	DMXL2 DCAF11 HERC1	1.54e-04	40	90	3	29078390
Pubmed	ARHGAP24 represses β-catenin transactivation-induced invasiveness in hepatocellular carcinoma mainly by acting as a GTPase-independent scaffold.	ZNF138 ZNF716 ZNF680 ZNF91 WDR1 NFS1 ZNF236	1.74e-04	451	90	7	36168627
Pubmed	The evolutionarily conserved Krüppel-associated box domain defines a subfamily of eukaryotic multifingered proteins.	ZNF92 ZNF91	1.84e-04	8	90	2	2023909
Pubmed	Novel activity of KRAB domain that functions to reinforce nuclear localization of KRAB-containing zinc finger proteins by interacting with KAP1.	ZNF300 ZNF91	2.36e-04	9	90	2	23665872
Pubmed	Cytoplasmic Metadherin (MTDH) provides survival advantage under conditions of stress by acting as RNA-binding protein.	ZXDC ZNF559 CCL20 MAP3K12 DOP1B	2.42e-04	214	90	5	22199357
Pubmed	Functional analysis of the SRY-KRAB interaction in mouse sex determination.	ZNF721 ZNF91	2.94e-04	10	90	2	18588511
Pubmed	Sry associates with the heterochromatin protein 1 complex by interacting with a KRAB domain protein.	ZNF721 ZNF91	3.59e-04	11	90	2	15469996
Pubmed	An interactome perturbation framework prioritizes damaging missense mutations for developmental disorders.	ZXDC LNX2 ZNF559 ZFP64 KLF15 FASTKD5 TRIM59	3.84e-04	514	90	7	29892012
Pubmed	Proteomic analysis of exosomes from human neural stem cells by flow field-flow fractionation and nanoflow liquid chromatography-tandem mass spectrometry.	RHOBTB3 IQCB1 CDKL1	3.99e-04	55	90	3	18570454
Pubmed	Overview of inactivating mutations in the protein-coding genome of the mouse reference strain C57BL/6J.	ZNF716 ZNF429 ZNF626	3.99e-04	55	90	3	29997285
Pubmed	Proteomic analysis and identification of cellular interactors of the giant ubiquitin ligase HERC2.	ZBTB5 FASTKD5 HERC1 HPS3	4.78e-04	139	90	4	25476789
Pubmed	Epigenetic gene silencing by the SRY protein is mediated by a KRAB-O protein that recruits the KAP1 co-repressor machinery.	ZNF721 ZNF91	5.07e-04	13	90	2	19850934
Pubmed	A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.	ZXDC ZBTB20 ZNF35 ZFP64 E4F1 PRDM4 TRIM59 ZNF292	5.12e-04	709	90	8	22988430
Pubmed	ZBTB20 is crucial for the specification of a subset of callosal projection neurons and astrocytes in the mammalian neocortex.	ZBTB20 ZBTB5 ZBTB41	5.95e-04	63	90	3	34351428
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	FXR1 TTC28 IQCB1 ZFP1 FASTKD5 UGGT2 DDX20 SPDL1	6.36e-04	733	90	8	34672954
Pubmed	Clustered organization of homologous KRAB zinc-finger genes with enhanced expression in human T lymphoid cells.	ZNF92 ZNF91	7.76e-04	16	90	2	8467795
Pubmed	Emergence of the ZNF91 Krüppel-associated box-containing zinc finger gene family in the last common ancestor of anthropoidea.	ZNF355P ZNF429	1.22e-03	20	90	2	7479878
Pubmed	Activation of the c-H-ras proto-oncogene by retrovirus insertion and chromosomal rearrangement in a Moloney leukemia virus-induced T-cell leukemia.	ZNF355P ZNF429	1.22e-03	20	90	2	2542606
Pubmed	Identifying new candidate genes for hereditary facial paresis on chromosome 3q21-q22 by RNA in situ hybridization in mouse.	ZXDC KLF15	1.22e-03	20	90	2	15953540
Pubmed	Vif hijacks CBF-β to degrade APOBEC3G and promote HIV-1 infection.	APOBEC3G DCAF11	1.35e-03	21	90	2	22190037
Pubmed	Nephronophthisis-Related Ciliopathies	ZNF423 IQCB1	1.35e-03	21	90	2	27336129
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	KLHL11 DMXL2 DENND4A THNSL1 TTC28 RHOBTB3 UGGT2	1.51e-03	650	90	7	38777146
Pubmed	Conserved beta-hairpin recognition by the GYF domains of Smy2 and GIGYF2 in mRNA surveillance and vesicular transport complexes.	FXR1 DDX20	1.62e-03	23	90	2	20696395
Pubmed	Functional genetic analysis of mouse chromosome 11.	ZNF423 WDR1	1.62e-03	23	90	2	12955145
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	DENND4A FXR1 TTC28 IQCB1 GRB10 RABGEF1 VIRMA DOP1B	1.77e-03	861	90	8	36931259
Pubmed	The sperm-associated antigen 6 interactome and its role in spermatogenesis.	FXR1 ERMP1 WDR17 TRIM59	1.81e-03	199	90	4	31146259
Pubmed	Discovery of genetic biomarkers contributing to variation in drug response of cytidine analogues using human lymphoblastoid cell lines.	LNX2 ZNF215	2.40e-03	28	90	2	24483146
Pubmed	Cytoplasmic aggregation of DDX1 in developing embryos: Early embryonic lethality associated with Ddx1 knockout.	BNC1 FXR1	2.57e-03	29	90	2	31330130
Interaction	ZFP37 interactions	ZFAT ZBTB20 ZNF423 KLF15 PRDM4 ZFP37	7.51e-08	49	89	6	int:ZFP37
Interaction	ZNF287 interactions	ZFAT ZBTB20 ZNF423 KLF15 PRDM4 ZFP37	2.59e-07	60	89	6	int:ZNF287
Interaction	ZBTB20 interactions	ZBTB20 ZNF423 PRDM4 VIRMA ZFP37	3.31e-06	52	89	5	int:ZBTB20
Interaction	ZNF667 interactions	ZBTB20 ZNF423 KLF15 PRDM4 ZFP37	3.64e-06	53	89	5	int:ZNF667
Interaction	ZNF473 interactions	ZFAT ZNF423 PRDM4 VIRMA ZFP37	4.80e-06	56	89	5	int:ZNF473
Interaction	ZSCAN10 interactions	ZFAT ZNF423 PRDM4 ZFP37	4.93e-06	26	89	4	int:ZSCAN10
Interaction	GZF1 interactions	ZBTB20 ZNF423 ZBTB47 E4F1 PRDM4 ZFP37	6.34e-06	103	89	6	int:GZF1
Interaction	ZFP3 interactions	ZFAT ZNF423 PRDM4 ZFP37	8.92e-06	30	89	4	int:ZFP3
Interaction	ZC3H12C interactions	IQCB1 FASTKD5 VIRMA	9.77e-06	10	89	3	int:ZC3H12C
Interaction	ZNF382 interactions	ZFAT ZNF423 PRDM4 ZFP37	1.32e-05	33	89	4	int:ZNF382
Interaction	ZNF697 interactions	ZBTB20 PRDM4 VIRMA ZFP37	1.32e-05	33	89	4	int:ZNF697
Interaction	ZNF8 interactions	ZBTB20 ZNF423 KLF15 VIRMA ZFP37	1.45e-05	70	89	5	int:ZNF8
Interaction	ZNF513 interactions	ZNF423 ZFP64 PRDM4 ZFP37	1.49e-05	34	89	4	int:ZNF513
Interaction	ZNF423 interactions	FXR1 ZBTB20 ZNF423 PRDM4 ZFP37	1.78e-05	73	89	5	int:ZNF423
Interaction	ZNF70 interactions	ZFP64 ZBTB47 E4F1 VIRMA	1.88e-05	36	89	4	int:ZNF70
Interaction	ZFP28 interactions	ZBTB20 ZNF423 PRDM4 ZFP37	2.10e-05	37	89	4	int:ZFP28
Interaction	RBAK interactions	KLHL11 ZFAT ZNF423 PRDM4 ZFP37	2.95e-05	81	89	5	int:RBAK
Interaction	GLI2 interactions	ZNF423 KLF15 HERC1 VIRMA ZFP37	7.74e-05	99	89	5	int:GLI2
Interaction	PRDM4 interactions	ZBTB20 ZNF423 PRDM4 ZFP37	8.18e-05	52	89	4	int:PRDM4
Interaction	CTCFL interactions	ZFAT ZNF423 PRDM4 ZFP37	1.63e-04	62	89	4	int:CTCFL
Cytoband	7q11.21	ZNF138 ZNF680 ZNF92 RABGEF1	2.25e-05	83	90	4	7q11.21
Cytoband	Ensembl 112 genes in cytogenetic band chr19p12	ZNF429 ZNF431 ZNF91 ZNF626	1.02e-04	122	90	4	chr19p12
Cytoband	Ensembl 112 genes in cytogenetic band chr7q11	ZNF138 ZNF680 ZNF92 RABGEF1 GSAP	2.02e-04	271	90	5	chr7q11
Cytoband	19p12	ZNF431 ZNF91 ZNF626	7.57e-04	90	90	3	19p12
Cytoband	Ensembl 112 genes in cytogenetic band chr4p16	ZNF141 ZNF721 ZNF518B WDR1	9.82e-04	222	90	4	chr4p16
Cytoband	9q22.33	TRMO ZNF510	1.93e-03	33	90	2	9q22.33
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZXDC BNC1 ZNF138 ZNF716 ZNF141 ZFAT ZBTB20 ZNF680 ZNF695 ZNF35 ZNF37A ZNF337 ZNF559 ZNF423 ZNF92 ZFP64 ZFP1 ZNF429 ZBTB5 ZNF300 ZBTB47 KLF15 ZNF431 ZNF215 ZNF721 ZBTB41 E4F1 ZNF510 ZNF518B ZNF91 ZNF519 ZNF236 ZNF626 PRDM4 ZNF614 ZFP37 ZNF551 ZNF292	5.79e-35	718	70	38	28
GeneFamily	Basic leucine zipper proteins\|BTB domain containing	KLHL11 ZBTB20 RHOBTB3 ZBTB5 ZBTB47 ZBTB41	1.32e-05	134	70	6	861
GeneFamily	VPS9 domain containing	RIN3 RABGEF1	6.52e-04	10	70	2	928
GeneFamily	WD repeat domain containing	DMXL2 DCAF11 WDR1 HERC1 WDR17	3.46e-03	262	70	5	362
Coexpression	DURAND_STROMA_NS_UP	BNC1 BRINP3 ZNF695 DUSP16 ZNF721 ZNF518B ZNF91	4.86e-06	194	90	7	MM962
Coexpression	GSE3982_EOSINOPHIL_VS_TH2_UP	RIN3 PPFIBP2 RHOBTB3 GRB10 RABGEF1 ZNF721 GSAP	5.02e-06	195	90	7	M5424
ToppCell	mild-B_cell\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ZFAT ZBTB20 ZNF680 PRDM4 ZNF551 AGBL3	2.82e-06	195	90	6	1e5f1967bcc898318f4e970b844b4a944eb168e5
ToppCell	Parenchymal-10x3prime_v2-Stromal-Myofibroblastic-Muscle_perivascular_immune_recruiting\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	FZD6 ZNF35 ZFP1 KLF15 UGGT2 WDR17	3.27e-06	200	90	6	a372ef3f9e6ff6e3c3376d6e10182977c5067788
ToppCell	TCGA-Uvea-Primary_Tumor-Uveal_Melanoma-Spindle_Cell-2\|TCGA-Uvea / Sample_Type by Project: Shred V9	FZD6 FXR1 ZBTB20 IQCB1 ZFP37	8.38e-06	136	90	5	b460669c13ed43ff3885acd38ce18f75d693738d
Drug	vinylene	ZFAT FXR1 ZNF423 ZFP64 ZNF300 APOBEC3G ZNF91 NFS1	5.35e-06	245	89	8	CID000006326
Drug	Mianserine hydrochloride [21535-47-7]; Up 200; 13.2uM; PC3; HT_HG-U133A	DENND4A ZBTB20 ZNF510 CCL20 WDR1 MAP3K12 ZMYM6	1.12e-05	194	89	7	2068_UP
Drug	Fenofibrate [49562-28-9]; Up 200; 11uM; MCF7; HT_HG-U133A	DENND4A THNSL1 GRB10 ZNF510 MAP3K12 ZNF614 ZNF551	1.19e-05	196	89	7	7432_UP
Drug	Sulfamethoxazole [723-46-6]; Up 200; 15.8uM; PC3; HT_HG-U133A	ZXDC BNC1 DENND4A ZBTB20 GSAP DCAF11 ZNF236	1.32e-05	199	89	7	7366_UP
Disease	eating disorder	ZFAT FXR1 CCL20	1.15e-04	32	87	3	EFO_0005203
Disease	Sepsis, mortality	RIN3 CHRM2	4.65e-04	11	87	2	EFO_0004352, HP_0100806
Disease	glycine measurement	PPFIBP2 EFCAB13 KLF15 ERMP1	7.35e-04	137	87	4	EFO_0009767
Disease	pulse pressure measurement	RIN3 ZNF716 ZFAT ZFHX4 TTC28 ZNF423 RXFP2 EFCAB13 ZBTB41 WDR1 CHRM2 TRIM59	7.78e-04	1392	87	12	EFO_0005763
Disease	atrial fibrillation	ZFAT ZFHX4 E4F1 WDR1 HERC1 ZNF292	8.14e-04	371	87	6	EFO_0000275
Disease	Cardiovascular Abnormalities	NOS2 ZNF292	1.00e-03	16	87	2	C0243050
Disease	Ureteral obstruction	CCL20 NOS2	2.27e-03	24	87	2	C0041956
Disease	complement factor D measurement	ZFAT ZNF518B ZNF519	2.65e-03	93	87	3	EFO_0020283
Disease	primary aldosteronism	DMXL2 RXFP2	2.67e-03	26	87	2	MONDO_0001422
Disease	resting heart rate, chronic obstructive pulmonary disease	RIN3 HERC1	3.54e-03	30	87	2	EFO_0000341, EFO_0004351
Disease	Streptozotocin Diabetes	CCL20 CHRM2 NOS2	4.04e-03	108	87	3	C0038433
Disease	Diabetes Mellitus, Experimental	CCL20 CHRM2 NOS2	4.04e-03	108	87	3	C0011853
Disease	Alloxan Diabetes	CCL20 CHRM2 NOS2	4.04e-03	108	87	3	C0002152

Protein segments in the cluster

Peptide	Gene	Start	Entry
KIVHKLFSLSKRCHK	BRINP3	371	Q76B58
LHHNLKSKIKECISF	AGBL3	786	Q8NEM8
AKFISKNKHVSLCIF	APOBEC3G	296	Q9HC16
KKTFKNACSVKIHHK	BNC1	726	Q01954
ALCNATFKKTFKHLL	CHRM2	441	P08172
SENLKLVHIVCHKKT	DFFB	296	O76075
HLHLKSVQACLAKAS	DMXL2	911	Q8TDJ6
AMAKLKHFHCRVLIS	DDX20	351	Q9UHI6
LLTKLCVHKDFKQHG	ERMP1	561	Q7Z2K6
VTQFKRALKKHAHLS	DENND4A	881	Q7Z401
ITKCSKHIFNAIKIT	RABGEF1	291	Q9UJ41
KQSLLFCPKSKLHIH	OCIAD2	21	Q56VL3
CKTKHVDHQSVSKAK	ANKRD34B	51	A5PLL1
FQDTLHHKAKGILTC	NOS2	96	P35228
KKHLITTQTEHKCVL	NFS1	146	Q9Y697
TKHLECTKQLAAAFH	FXR1	206	P51114
THALKTCFKVLSKVQ	DOP1B	526	Q9Y3R5
EHHSFLKLCLKLLSN	HERC1	786	Q15751
LHFKLCKKSSILVHK	LNX2	91	Q8N448
LSGHIVKKLTNHKAC	DCAF11	471	Q8TEB1
FHLHSQKCLGLDITK	LY75	76	O60449
FLKVTSQLHHLSIKC	PPFIBP2	671	Q8ND30
LSIKCAIHVLHVNKF	PPFIBP2	681	Q8ND30
LVRKLHKCVSQHFLK	MAB21L3	311	Q8N8X9
SCEFFLKHNSKVKHK	FZD6	526	O60353
KFSKHLTLCVFTNHT	GSAP	276	A4D1B5
HISLCHSAKKVKNIC	FASTKD5	46	Q7L8L6
LKKKLHLSNCVAIHS	KLHL11	196	Q9NVR0
KSRKHHCFTETSKLQ	CDKL1	311	Q00532
HSAKHKVDIDCSQKV	DUSP16	71	Q9BY84
LHSKELSALHKACKI	EFCAB13	166	Q8IY85
KLHFEKIKSEGTCLH	MAP3K12	391	Q12852
AAKAKQAHLTTLKHI	IQCB1	546	Q15051
CEKKFARSDHLSKHI	KLF15	386	Q9UIH9
PKAFVLTLCHHQKIK	GRB10	526	Q13322
LCHKTFKTGSILKAH	E4F1	196	Q66K89
ESHCSLQIKALAKIH	CMTR1	501	Q8N1G2
KCDKLFLRTNHLKKH	PRDM4	706	Q9UKN5
LLKKAKFHHSDCLST	RHOBTB3	536	O94955
LKEAINSCLHQIHSK	RIN3	691	Q8TB24
KRVSHSHTLKQKCLE	HHLA1	511	C9JL84
KAICHFKNHIILLTK	HPS3	436	Q969F9
KHQVDHQKELLSCKS	SPDL1	131	Q96EA4
TKLKKIFLQHNCIRH	RXFP2	161	Q8WXD0
DNLKLKKTGFHCLHV	WDR17	306	Q8IZU2
IKGHSKSIQCLTVHK	WDR1	316	O75083
NAIIFHTKKKLSVCA	CCL20	61	P78556
GKSFCVKSKLIAHHR	ZNF37A	501	P17032
VCKKTFSHKANLIKH	ZFP1	216	Q6P2D0
KSFCMLLHLSQHKRI	ZNF431	211	Q8TF32
HQKIHSLEKTFKCNE	ZNF35	296	P13682
LFVFHKNGHLSCKAK	TRMO	86	Q9BU70
HCSLAFKTMQKLQIH	ZFHX4	1356	Q86UP3
SFCMLSQLTQHKKIH	ZNF92	181	Q03936
CNKVFKFKHSLQAHL	ZFAT	276	Q9P243
LHLNSVVKACKHYLT	ZBTB5	106	O15062
AFNLCSVLTKHKKIH	ZNF695	276	Q8IW36
QCALAFAKKHQLKVH	ZXDC	181	Q2QGD7
KKCIIVFSQSHLKGH	ZNF519	241	Q8TB69
CGKAFHQSSILTKHK	ZNF138	171	P52744
LEHLVFHKTQLQKKC	TMEM232	286	C9JQI7
YCNKLHASKKTLAKH	ZBTB41	426	Q5SVQ8
KECGKAFIHSLHLNK	ZNF721	436	Q8TF20
ESFSKKCHLILHKII	ZNF551	286	Q7Z340
SNIIRHYKCHKLSKA	ZNF292	2401	O60281
AFNCSSTLKKHKIIH	ZNF716	416	A6NP11
RCHHLKKITQKCFSS	THNSL1	6	Q8IYQ7
KCFSSIHVKTDKHAQ	THNSL1	16	Q8IYQ7
KAHKEKCFRVSHTLA	ZBTB47	676	Q9UFB7
CDKAFKRFSHLNKHK	ZNF141	456	Q15928
ICKKKFSHKTLLERH	ZBTB20	666	Q9HC78
AFKCSSNLTTHKKIH	ZNF626	461	Q68DY1
KCVKSFCIRLHKTQH	ZNF91	186	Q05481
DTALKLHKTHLCIAQ	TTC28	491	Q96AY4
VKLKCQHCNHLFATK	ZMYM6	426	O95789
SFCMLSQLTQHKKIH	ZNF429	181	Q86V71
NLTKHQKLHAEAKAC	ZNF215	421	Q9UL58
TAHIKTHTGIKAFKC	ZNF236	526	Q9UL36
KAHIRTHTGLKSFKC	ZNF236	701	Q9UL36
KKHLHLNQCGKSFEK	ZNF510	306	Q9Y2H8
CVRVFKHSSKLNEHK	ZNF355P	396	Q9NSJ1
FCSKAFHAIILLEKH	ZNF423	811	Q2M1K9
NAFVVIHKKHTCKIN	UGGT2	136	Q9NYU1
ENAKCIHTKFQVFKH	ZNF614	181	Q8N883
KTSQNLHLVCKKTHT	ZNF559	166	Q9BR84
ALASHKACKLAILHL	VIRMA	1231	Q69YN4
KLCCHSSSHIKQDKI	ZFP37	251	Q9Y6Q3
CGKAFSKKSHLIIHQ	ZFP37	466	Q9Y6Q3
AFNQSSTLIKHKKIH	ZNF680	246	Q8NEM1
NLKSHIRIKHTFKCL	ZFP64	456	Q9NTW7
KAFCEKSHLIIHKRI	ZNF300	416	Q96RE9
SNSLHKVKNILCHIF	TRIM59	376	Q8IWR1
IIHKKAHSRQKLFTC	ZNF337	196	Q9Y3M9
KKHTLQHEEIKFICS	ZNF518B	151	Q9C0D4