Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	delayed rectifier potassium channel activity	KCNG2 KCNA1 KCNA3 KCNA4 KCNA5 KCNA6 KCNA10 KCNC1	1.04e-15	28	45	8	GO:0005251
GeneOntologyMolecularFunction	voltage-gated monoatomic ion channel activity	KCNG2 KCNA1 KCNA3 KCNA4 KCNA5 KCNA6 KCNA10 CLCN6 KCNC1 GRM7	7.47e-12	182	45	10	GO:0005244
GeneOntologyMolecularFunction	voltage-gated channel activity	KCNG2 KCNA1 KCNA3 KCNA4 KCNA5 KCNA6 KCNA10 CLCN6 KCNC1 GRM7	8.33e-12	184	45	10	GO:0022832
GeneOntologyMolecularFunction	voltage-gated monoatomic cation channel activity	KCNG2 KCNA1 KCNA3 KCNA4 KCNA5 KCNA6 KCNA10 KCNC1 GRM7	4.74e-11	152	45	9	GO:0022843
GeneOntologyMolecularFunction	voltage-gated potassium channel activity	KCNG2 KCNA1 KCNA3 KCNA4 KCNA5 KCNA6 KCNA10 KCNC1	6.47e-11	102	45	8	GO:0005249
GeneOntologyMolecularFunction	gated channel activity	KCNG2 KCNA1 KCNA3 KCNA4 KCNA5 KCNA6 KCNA10 CLCN6 KCNC1 RASA3 GRM7	1.49e-10	334	45	11	GO:0022836
GeneOntologyMolecularFunction	potassium channel activity	KCNG2 KCNA1 KCNA3 KCNA4 KCNA5 KCNA6 KCNA10 KCNC1	4.04e-10	128	45	8	GO:0005267
GeneOntologyMolecularFunction	potassium ion transmembrane transporter activity	KCNG2 KCNA1 KCNA3 KCNA4 KCNA5 KCNA6 KCNA10 KCNC1	3.35e-09	167	45	8	GO:0015079
GeneOntologyMolecularFunction	monoatomic cation channel activity	KCNG2 KCNA1 KCNA3 KCNA4 KCNA5 KCNA6 KCNA10 KCNC1 RASA3 GRM7	3.67e-09	343	45	10	GO:0005261
GeneOntologyMolecularFunction	monoatomic ion channel activity	KCNG2 KCNA1 KCNA3 KCNA4 KCNA5 KCNA6 KCNA10 CLCN6 KCNC1 RASA3 GRM7	4.22e-09	459	45	11	GO:0005216
GeneOntologyMolecularFunction	metal ion transmembrane transporter activity	KCNG2 KCNA1 KCNA3 KCNA4 KCNA5 KCNA6 KCNA10 KCNC1 RASA3 GRM7 ATP2A1	4.83e-09	465	45	11	GO:0046873
GeneOntologyMolecularFunction	channel activity	KCNG2 KCNA1 KCNA3 KCNA4 KCNA5 KCNA6 KCNA10 CLCN6 KCNC1 RASA3 GRM7	1.69e-08	525	45	11	GO:0015267
GeneOntologyMolecularFunction	passive transmembrane transporter activity	KCNG2 KCNA1 KCNA3 KCNA4 KCNA5 KCNA6 KCNA10 CLCN6 KCNC1 RASA3 GRM7	1.72e-08	526	45	11	GO:0022803
GeneOntologyMolecularFunction	inorganic molecular entity transmembrane transporter activity	KCNG2 KCNA1 KCNA3 KCNA4 KCNA5 KCNA6 KCNA10 CLCN6 KCNC1 RASA3 GRM7 ATP2A1	7.45e-08	758	45	12	GO:0015318
GeneOntologyMolecularFunction	inorganic cation transmembrane transporter activity	KCNG2 KCNA1 KCNA3 KCNA4 KCNA5 KCNA6 KCNA10 KCNC1 RASA3 GRM7 ATP2A1	1.03e-07	627	45	11	GO:0022890
GeneOntologyMolecularFunction	monoatomic ion transmembrane transporter activity	KCNG2 KCNA1 KCNA3 KCNA4 KCNA5 KCNA6 KCNA10 CLCN6 KCNC1 RASA3 GRM7 ATP2A1	1.22e-07	793	45	12	GO:0015075
GeneOntologyMolecularFunction	monoatomic cation transmembrane transporter activity	KCNG2 KCNA1 KCNA3 KCNA4 KCNA5 KCNA6 KCNA10 KCNC1 RASA3 GRM7 ATP2A1	1.83e-07	664	45	11	GO:0008324
GeneOntologyMolecularFunction	voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	KCNA1 KCNA4 KCNC1	7.11e-06	17	45	3	GO:0099508
GeneOntologyMolecularFunction	transmembrane transporter activity	KCNG2 KCNA1 KCNA3 KCNA4 KCNA5 KCNA6 KCNA10 CLCN6 KCNC1 RASA3 GRM7 ATP2A1	7.99e-06	1180	45	12	GO:0022857
GeneOntologyMolecularFunction	transporter activity	KCNG2 KCNA1 KCNA3 KCNA4 KCNA5 KCNA6 KCNA10 CLCN6 KCNC1 RASA3 GRM7 ATP2A1	1.95e-05	1289	45	12	GO:0005215
GeneOntologyMolecularFunction	UDP-glucosyltransferase activity	GYS2 UGGT1	3.81e-04	13	45	2	GO:0035251
GeneOntologyMolecularFunction	glucosyltransferase activity	GYS2 UGGT1	1.11e-03	22	45	2	GO:0046527
GeneOntologyMolecularFunction	outward rectifier potassium channel activity	KCNA3 KCNA5	1.68e-03	27	45	2	GO:0015271
GeneOntologyMolecularFunction	intracellularly ligand-gated monoatomic ion channel activity	KCNA10 RASA3	2.51e-03	33	45	2	GO:0005217
GeneOntologyMolecularFunction	calcium ion transmembrane transporter activity	RASA3 GRM7 ATP2A1	4.77e-03	151	45	3	GO:0015085
GeneOntologyMolecularFunction	ion channel regulator activity	DPP6 GRM7 SGK1	5.80e-03	162	45	3	GO:0099106
GeneOntologyMolecularFunction	calcium channel regulator activity	GRM7 SGK1	6.60e-03	54	45	2	GO:0005246
GeneOntologyMolecularFunction	channel regulator activity	DPP6 GRM7 SGK1	7.06e-03	174	45	3	GO:0016247
GeneOntologyMolecularFunction	potassium channel regulator activity	DPP6 SGK1	7.33e-03	57	45	2	GO:0015459
GeneOntologyMolecularFunction	transporter regulator activity	DPP6 GRM7 SGK1	7.40e-03	177	45	3	GO:0141108
GeneOntologyBiologicalProcess	action potential	KCNG2 DPP6 KCNA1 KCNA3 KCNA4 KCNA5 KCNA6 KCNA10 KCNC1	4.33e-10	201	45	9	GO:0001508
GeneOntologyBiologicalProcess	protein homooligomerization	BEND3 KCNG2 KCNA1 KCNA3 KCNA4 KCNA5 KCNA6 KCNA10 KCNC1	1.13e-09	224	45	9	GO:0051260
GeneOntologyBiologicalProcess	potassium ion transmembrane transport	KCNG2 DPP6 KCNA1 KCNA3 KCNA4 KCNA5 KCNA6 KCNA10 KCNC1	1.54e-09	232	45	9	GO:0071805
GeneOntologyBiologicalProcess	potassium ion transport	KCNG2 DPP6 KCNA1 KCNA3 KCNA4 KCNA5 KCNA6 KCNA10 KCNC1	6.18e-09	272	45	9	GO:0006813
GeneOntologyBiologicalProcess	protein complex oligomerization	BEND3 KCNG2 KCNA1 KCNA3 KCNA4 KCNA5 KCNA6 KCNA10 KCNC1	1.29e-08	296	45	9	GO:0051259
GeneOntologyBiologicalProcess	metal ion transport	KCNG2 DPP6 PRKCE PLCG1 KCNA1 KCNA3 KCNA4 KCNA5 KCNA6 KCNA10 KCNC1 ATP2A1 SGK1	1.30e-07	1000	45	13	GO:0030001
GeneOntologyBiologicalProcess	inorganic ion transmembrane transport	KCNG2 DPP6 PRKCE PLCG1 KCNA1 KCNA3 KCNA4 KCNA5 KCNA6 KCNA10 CLCN6 KCNC1 ATP2A1	1.58e-07	1017	45	13	GO:0098660
GeneOntologyBiologicalProcess	regulation of membrane potential	KCNG2 DPP6 PRKCE KCNA1 KCNA3 KCNA4 KCNA5 KCNA6 KCNA10 KCNC1	2.68e-07	559	45	10	GO:0042391
GeneOntologyBiologicalProcess	inorganic cation transmembrane transport	KCNG2 DPP6 PRKCE PLCG1 KCNA1 KCNA3 KCNA4 KCNA5 KCNA6 KCNA10 KCNC1 ATP2A1	4.35e-07	922	45	12	GO:0098662
GeneOntologyBiologicalProcess	monoatomic ion transmembrane transport	KCNG2 DPP6 PRKCE PLCG1 KCNA1 KCNA3 KCNA4 KCNA5 KCNA6 KCNA10 CLCN6 KCNC1 ATP2A1	4.54e-07	1115	45	13	GO:0034220
GeneOntologyBiologicalProcess	monoatomic cation transmembrane transport	KCNG2 DPP6 PRKCE PLCG1 KCNA1 KCNA3 KCNA4 KCNA5 KCNA6 KCNA10 KCNC1 ATP2A1	5.47e-07	942	45	12	GO:0098655
GeneOntologyBiologicalProcess	monoatomic cation transport	KCNG2 DPP6 PRKCE PLCG1 KCNA1 KCNA3 KCNA4 KCNA5 KCNA6 KCNA10 KCNC1 ATP2A1 SGK1	6.91e-07	1157	45	13	GO:0006812
GeneOntologyBiologicalProcess	monoatomic ion transport	KCNG2 DPP6 PRKCE PLCG1 KCNA1 KCNA3 KCNA4 KCNA5 KCNA6 KCNA10 CLCN6 KCNC1 ATP2A1 SGK1	7.47e-07	1374	45	14	GO:0006811
GeneOntologyBiologicalProcess	optic nerve development	KCNA1 KCNA3 KCNC1	1.45e-05	22	45	3	GO:0021554
GeneOntologyBiologicalProcess	regulation of presynaptic membrane potential	KCNA1 KCNA4 KCNC1	4.60e-05	32	45	3	GO:0099505
GeneOntologyBiologicalProcess	corpus callosum development	KCNA1 KCNA3 KCNC1	5.06e-05	33	45	3	GO:0022038
GeneOntologyBiologicalProcess	regulation of metal ion transport	DPP6 PRKCE PLCG1 KCNA5 KCNC1 ATP2A1 SGK1	8.83e-05	493	45	7	GO:0010959
GeneOntologyBiologicalProcess	regulation of monoatomic ion transport	DPP6 PRKCE PLCG1 KCNA5 KCNC1 ATP2A1 SGK1	2.33e-04	577	45	7	GO:0043269
GeneOntologyBiologicalProcess	positive regulation of monoatomic ion transport	DPP6 PLCG1 KCNC1 ATP2A1 SGK1	2.75e-04	266	45	5	GO:0043270
GeneOntologyBiologicalProcess	regulation of mRNA processing	SLTM CWC22 SRSF9 RBM10	3.87e-04	158	45	4	GO:0050684
GeneOntologyBiologicalProcess	cranial nerve development	KCNA1 KCNA3 KCNC1	4.22e-04	67	45	3	GO:0021545
GeneOntologyBiologicalProcess	cellular response to prostaglandin E stimulus	PRKCE AKAP8	5.48e-04	16	45	2	GO:0071380
GeneOntologyBiologicalProcess	positive regulation of cation transmembrane transport	DPP6 PLCG1 KCNC1 ATP2A1	5.57e-04	174	45	4	GO:1904064
GeneOntologyBiologicalProcess	positive regulation of monoatomic ion transmembrane transport	DPP6 PLCG1 KCNC1 ATP2A1	8.05e-04	192	45	4	GO:0034767
GeneOntologyCellularComponent	voltage-gated potassium channel complex	KCNG2 DPP6 KCNA1 KCNA3 KCNA4 KCNA5 KCNA6 KCNA10 KCNC1	2.92e-13	91	45	9	GO:0008076
GeneOntologyCellularComponent	potassium channel complex	KCNG2 DPP6 KCNA1 KCNA3 KCNA4 KCNA5 KCNA6 KCNA10 KCNC1	1.00e-12	104	45	9	GO:0034705
GeneOntologyCellularComponent	cation channel complex	KCNG2 DPP6 KCNA1 KCNA3 KCNA4 KCNA5 KCNA6 KCNA10 KCNC1 ATP2A1	6.02e-11	235	45	10	GO:0034703
GeneOntologyCellularComponent	monoatomic ion channel complex	KCNG2 DPP6 KCNA1 KCNA3 KCNA4 KCNA5 KCNA6 KCNA10 KCNC1 ATP2A1	6.03e-09	378	45	10	GO:0034702
GeneOntologyCellularComponent	transmembrane transporter complex	KCNG2 DPP6 KCNA1 KCNA3 KCNA4 KCNA5 KCNA6 KCNA10 KCNC1 ATP2A1	1.28e-07	523	45	10	GO:1902495
GeneOntologyCellularComponent	transporter complex	KCNG2 DPP6 KCNA1 KCNA3 KCNA4 KCNA5 KCNA6 KCNA10 KCNC1 ATP2A1	2.04e-07	550	45	10	GO:1990351
GeneOntologyCellularComponent	plasma membrane protein complex	KCNG2 DPP6 KCNA1 KCNA3 KCNA4 KCNA5 KCNA6 KCNA10 KCNC1 GNA13	5.09e-06	785	45	10	GO:0098797
GeneOntologyCellularComponent	nuclear speck	CWC22 SRSF9 SGK1 RBM10 ZC3H13 KAT6A YLPM1	3.48e-05	431	45	7	GO:0016607
GeneOntologyCellularComponent	calyx of Held	KCNA1 KCNA3 KCNC1	6.33e-05	36	45	3	GO:0044305
GeneOntologyCellularComponent	axon terminus	KCNA1 KCNA3 KCNA6 KCNC1 GRM7	8.60e-05	210	45	5	GO:0043679
GeneOntologyCellularComponent	neuron projection terminus	KCNA1 KCNA3 KCNA6 KCNC1 GRM7	1.40e-04	233	45	5	GO:0044306
GeneOntologyCellularComponent	membrane protein complex	KCNG2 DPP6 KCNA1 KCNA3 KCNA4 KCNA5 KCNA6 KCNA10 KCNC1 ATP2A1 GNA13	2.58e-04	1498	45	11	GO:0098796
GeneOntologyCellularComponent	presynaptic membrane	KCNA1 KCNA3 KCNA4 KCNC1 GRM7	3.12e-04	277	45	5	GO:0042734
GeneOntologyCellularComponent	nuclear body	SLTM CWC22 SRSF9 SGK1 RBM10 ZC3H13 KAT6A YLPM1	6.11e-04	903	45	8	GO:0016604
GeneOntologyCellularComponent	main axon	KCNA1 KCNA4 KCNC1	9.30e-04	89	45	3	GO:0044304
GeneOntologyCellularComponent	postsynaptic membrane	KCNA1 KCNA3 KCNA4 KCNC1 GRM7	1.72e-03	405	45	5	GO:0045211
GeneOntologyCellularComponent	axon initial segment	KCNA1 KCNA4	1.77e-03	29	45	2	GO:0043194
GeneOntologyCellularComponent	distal axon	KCNA1 KCNA3 KCNA6 KCNC1 GRM7	2.35e-03	435	45	5	GO:0150034
GeneOntologyCellularComponent	presynapse	PRKCE KCNA1 KCNA3 KCNA4 KCNA6 KCNC1 GRM7	2.67e-03	886	45	7	GO:0098793
Domain	K_chnl_volt-dep_Kv	KCNG2 KCNA1 KCNA3 KCNA4 KCNA5 KCNA6 KCNA10 KCNC1	1.26e-15	27	45	8	IPR003968
Domain	K_chnl_volt-dep_Kv1	KCNA1 KCNA3 KCNA4 KCNA5 KCNA6 KCNA10	3.86e-15	8	45	6	IPR003972
Domain	VG_K_chnl	KCNG2 KCNA1 KCNA3 KCNA4 KCNA5 KCNA6 KCNA10 KCNC1	7.81e-15	33	45	8	IPR028325
Domain	BTB_2	KCNG2 KCNA1 KCNA3 KCNA4 KCNA5 KCNA6 KCNA10 KCNC1	4.81e-13	53	45	8	PF02214
Domain	T1-type_BTB	KCNG2 KCNA1 KCNA3 KCNA4 KCNA5 KCNA6 KCNA10 KCNC1	4.81e-13	53	45	8	IPR003131
Domain	Channel_four-helix_dom	KCNG2 KCNA1 KCNA3 KCNA4 KCNA5 KCNA6 KCNA10 KCNC1	8.91e-13	57	45	8	IPR027359
Domain	-	KCNG2 KCNA1 KCNA3 KCNA4 KCNA5 KCNA6 KCNA10 KCNC1	8.91e-13	57	45	8	1.20.120.350
Domain	Ion_trans_dom	KCNG2 KCNA1 KCNA3 KCNA4 KCNA5 KCNA6 KCNA10 KCNC1	2.68e-10	114	45	8	IPR005821
Domain	Ion_trans	KCNG2 KCNA1 KCNA3 KCNA4 KCNA5 KCNA6 KCNA10 KCNC1	2.68e-10	114	45	8	PF00520
Domain	BTB	KCNG2 KCNA1 KCNA3 KCNA4 KCNA5 KCNA6 KCNA10 KCNC1	1.01e-08	180	45	8	SM00225
Domain	BTB/POZ_dom	KCNG2 KCNA1 KCNA3 KCNA4 KCNA5 KCNA6 KCNA10 KCNC1	1.25e-08	185	45	8	IPR000210
Domain	SKP1/BTB/POZ	KCNG2 KCNA1 KCNA3 KCNA4 KCNA5 KCNA6 KCNA10 KCNC1	1.48e-08	189	45	8	IPR011333
Domain	Pkinase_C	PRKCE SGK1	3.58e-03	37	45	2	IPR017892
Domain	C2	PRKCE PLCG1 RASA3	3.86e-03	131	45	3	PF00168
Domain	C2	PRKCE PLCG1 RASA3	4.37e-03	137	45	3	SM00239
Domain	Pkinase_C	PRKCE SGK1	4.60e-03	42	45	2	PF00433
Domain	C2	PRKCE PLCG1 RASA3	4.83e-03	142	45	3	PS50004
Domain	-	PRKCE PLCG1 RASA3	5.42e-03	148	45	3	2.60.40.150
Domain	C2_dom	PRKCE PLCG1 RASA3	7.20e-03	164	45	3	IPR000008
Domain	AGC-kinase_C	PRKCE SGK1	8.05e-03	56	45	2	IPR000961
Domain	AGC_KINASE_CTER	PRKCE SGK1	8.05e-03	56	45	2	PS51285
Domain	S_TK_X	PRKCE SGK1	8.05e-03	56	45	2	SM00133
Pathway	REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS	KCNG2 KCNA1 KCNA3 KCNA4 KCNA5 KCNA6 KCNA10 KCNC1	3.26e-14	41	33	8	MM14546
Pathway	REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS	KCNG2 KCNA1 KCNA3 KCNA4 KCNA5 KCNA6 KCNA10 KCNC1	4.93e-14	43	33	8	M1056
Pathway	REACTOME_POTASSIUM_CHANNELS	KCNG2 KCNA1 KCNA3 KCNA4 KCNA5 KCNA6 KCNA10 KCNC1	4.91e-11	98	33	8	MM14545
Pathway	REACTOME_POTASSIUM_CHANNELS	KCNG2 KCNA1 KCNA3 KCNA4 KCNA5 KCNA6 KCNA10 KCNC1	7.36e-11	103	33	8	M1073
Pathway	REACTOME_NEURONAL_SYSTEM	KCNG2 KCNA1 KCNA3 KCNA4 KCNA5 KCNA6 KCNA10 KCNC1	7.73e-07	335	33	8	MM14503
Pathway	REACTOME_NEURONAL_SYSTEM	KCNG2 KCNA1 KCNA3 KCNA4 KCNA5 KCNA6 KCNA10 KCNC1	3.57e-06	411	33	8	M735
Pathway	WP_ADHD_AND_AUTISM_ASD_PATHWAYS	PLCG1 KCNA1 KCNA3 KCNA4 KCNA5 KCNA6 GRM7	1.82e-05	367	33	7	M48346
Pathway	BIOCARTA_BARRESTIN_PATHWAY	KCNA3 KCNA4	2.88e-04	11	33	2	MM1501
Pathway	BIOCARTA_BARRESTIN_PATHWAY	KCNA1 KCNA3	3.46e-04	12	33	2	M7772
Pathway	PID_LYSOPHOSPHOLIPID_PATHWAY	PRKCE PLCG1 GNA13	4.62e-04	65	33	3	M15
Pathway	BIOCARTA_BARR_MAPK_PATHWAY	KCNA1 KCNA3	4.75e-04	14	33	2	M668
Pathway	PID_S1P_S1P4_PATHWAY	PLCG1 GNA13	4.75e-04	14	33	2	M64
Pathway	BIOCARTA_BARR_MAPK_PATHWAY	KCNA3 KCNA4	4.75e-04	14	33	2	MM1489
Pathway	BIOCARTA_PTDINS_PATHWAY	PRKCE PLCG1	6.25e-04	16	33	2	MM1454
Pathway	BIOCARTA_BARRESTIN_SRC_PATHWAY	KCNA1 KCNA3	7.07e-04	17	33	2	M111
Pathway	BIOCARTA_BARRESTIN_SRC_PATHWAY	KCNA3 KCNA4	7.07e-04	17	33	2	MM1491
Pathway	WP_CALCIUM_MEDIATED_TCELL_APOPTOSIS_INVOLVED_IN_INCLUSION_BODY_MYOSITIS	PLCG1 ATP2A1	9.83e-04	20	33	2	M48330
Pathway	PID_ECADHERIN_KERATINOCYTE_PATHWAY	PLCG1 AJUBA	1.09e-03	21	33	2	M184
Pathway	WP_G_PROTEIN_SIGNALING_PATHWAYS	PRKCE AKAP8 GNA13	1.20e-03	90	33	3	MM15882
Pathway	WP_G_PROTEIN_SIGNALING	PRKCE AKAP8 GNA13	1.23e-03	91	33	3	M39426
Pathway	BIOCARTA_PTDINS_PATHWAY	PRKCE PLCG1	1.30e-03	23	33	2	M8809
Pubmed	International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels.	KCNG2 KCNA1 KCNA3 KCNA4 KCNA5 KCNA6 KCNA10 KCNC1	3.03e-16	40	45	8	16382104
Pubmed	Developmental expression of voltage-sensitive K+ channels in mouse skeletal muscle and C2C12 cells.	KCNA1 KCNA3 KCNA4 KCNA5 KCNA6 KCNC1	6.94e-16	10	45	6	1383027
Pubmed	Physical mapping of potassium channel gene clusters on mouse chromosomes three and six.	KCNA1 KCNA3 KCNA5 KCNA6 KCNA10	1.73e-14	6	45	5	9286706
Pubmed	Ion channel expression in the developing enteric nervous system.	KCNA1 KCNA4 KCNA5 KCNA6 CLCN6 KCNC1	7.48e-12	37	45	6	25798587
Pubmed	Truncation of the Shaker-like voltage-gated potassium channel, Kv1.1, causes megencephaly.	KCNA1 KCNA3 KCNA4 KCNA6	3.66e-11	6	45	4	14686897
Pubmed	Pore size matters for potassium channel conductance.	KCNA1 KCNA4 KCNA6 KCNA10	8.53e-11	7	45	4	27619418
Pubmed	Heteromultimeric delayed-rectifier K+ channels in schwann cells: developmental expression and role in cell proliferation.	KCNA1 KCNA4 KCNA5 KCNC1	8.53e-11	7	45	4	9852577
Pubmed	N-terminal PDZ-binding domain in Kv1 potassium channels.	KCNA1 KCNA3 KCNA4 KCNA5	1.70e-10	8	45	4	12435606
Pubmed	Chromosomal mapping in the mouse of eight K(+)-channel genes representing the four Shaker-like subfamilies Shaker, Shab, Shaw, and Shal.	KCNA1 KCNA3 KCNA4 KCNA5 KCNA6	1.86e-10	26	45	5	7905852
Pubmed	Voltage-gated potassium channel genes are clustered in paralogous regions of the mouse genome.	KCNA1 KCNA3 KCNA5 KCNA6 KCNA10	4.78e-10	31	45	5	8034307
Pubmed	Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development.	KCNA1 KCNA3 KCNA4 KCNA5 KCNA6 CLCN6 KCNC1	5.59e-10	139	45	7	16985003
Pubmed	Sequence and functional expression in Xenopus oocytes of a human insulinoma and islet potassium channel.	KCNA3 KCNA4 KCNA5	2.02e-09	3	45	3	1986382
Pubmed	Characterization of a voltage-activated K-channel gene cluster on human chromosome 12p13.	KCNA1 KCNA5 KCNA6	2.02e-09	3	45	3	8821794
Pubmed	Contribution of Kv1.2 voltage-gated potassium channel to D2 autoreceptor regulation of axonal dopamine overflow.	KCNA1 KCNA3 KCNA6	2.02e-08	5	45	3	21233214
Pubmed	Subunit composition of Kv1 channels in human CNS.	KCNA1 KCNA3 KCNA4	2.02e-08	5	45	3	10428084
Pubmed	Molecular genetic analysis of distal mouse chromosome 6 defines gene order and positions of the deafwaddler and opisthotonos mutations.	KCNA1 KCNA5 KCNA6	4.04e-08	6	45	3	8530061
Pubmed	Differential K+ channel clustering activity of PSD-95 and SAP97, two related membrane-associated putative guanylate kinases.	KCNA1 KCNA3 KCNA4	4.04e-08	6	45	3	8938729
Pubmed	Clustering of Shaker-type K+ channels by interaction with a family of membrane-associated guanylate kinases.	KCNA1 KCNA3 KCNA4	7.06e-08	7	45	3	7477295
Pubmed	KCNE2 forms potassium channels with KCNA3 and KCNQ1 in the choroid plexus epithelium.	KCNA1 KCNA3 KCNA6	1.13e-07	8	45	3	21859894
Pubmed	Genomic organization, chromosomal localization, tissue distribution, and biophysical characterization of a novel mammalian Shaker-related voltage-gated potassium channel, Kv1.7.	KCNA1 KCNA3 KCNA6	1.69e-07	9	45	3	9488722
Pubmed	Genomic organization, nucleotide sequence, biophysical properties, and localization of the voltage-gated K+ channel gene KCNA4/Kv1.4 to mouse chromosome 2/human 11p14 and mapping of KCNC1/Kv3.1 to mouse 7/human 11p14.3-p15.2 and KCNA1/Kv1.1 to human 12p13.	KCNA1 KCNA4 KCNC1	3.32e-07	11	45	3	8020965
Pubmed	Alteration of Neuronal Excitability and Short-Term Synaptic Plasticity in the Prefrontal Cortex of a Mouse Model of Mental Illness.	KCNA1 KCNA3 KCNA6	1.12e-06	16	45	3	28283561
Pubmed	Multiple mRNA isoforms encoding the mouse cardiac Kv1-5 delayed rectifier K+ channel.	KCNA1 KCNA5	1.64e-06	2	45	2	8226976
Pubmed	Association of Kv1.5 and Kv1.3 contributes to the major voltage-dependent K+ channel in macrophages.	KCNA3 KCNA5	1.64e-06	2	45	2	17038323
Pubmed	Molecular cloning, characterization, and genomic localization of a human potassium channel gene.	KCNA1 KCNA5	1.64e-06	2	45	2	1349297
Pubmed	Potassium channels Kv1.3 and Kv1.5 are expressed on blood-derived dendritic cells in the central nervous system.	KCNA3 KCNA5	1.64e-06	2	45	2	16729292
Pubmed	Kv1.3/Kv1.5 heteromeric channels compromise pharmacological responses in macrophages.	KCNA3 KCNA5	1.64e-06	2	45	2	17157812
Pubmed	A C-terminally amidated analogue of ShK is a potent and selective blocker of the voltage-gated potassium channel Kv1.3.	KCNA1 KCNA3	1.64e-06	2	45	2	23063513
Pubmed	Myocardin-Dependent Kv1.5 Channel Expression Prevents Phenotypic Modulation of Human Vessels in Organ Culture.	KCNA3 KCNA5	1.64e-06	2	45	2	31597447
Pubmed	Molecular cloning and characterization of two voltage-gated K+ channel cDNAs from human ventricle.	KCNA4 KCNA5	1.64e-06	2	45	2	2001794
Pubmed	Functional role of Kv1.1 and Kv1.3 channels in the neoplastic progression steps of three cancer cell lines, elucidated by scorpion peptides.	KCNA1 KCNA3	1.64e-06	2	45	2	29415410
Pubmed	N-glycans modulate K(v)1.5 gating but have no effect on K(v)1.4 gating.	KCNA4 KCNA5	1.64e-06	2	45	2	19961828
Pubmed	Disinactivation of N-type inactivation of voltage-gated K channels by an erbstatin analogue.	KCNA1 KCNA4	1.64e-06	2	45	2	15136567
Pubmed	Episodic ataxia type 1 mutations affect fast inactivation of K+ channels by a reduction in either subunit surface expression or affinity for inactivation domain.	KCNA1 KCNA4	1.64e-06	2	45	2	21307345
Pubmed	Differential expression of Kv1.3 and Kv1.5 voltage-dependent K+ channels in human skeletal muscle sarcomas.	KCNA3 KCNA5	1.64e-06	2	45	2	22360360
Pubmed	Expression of voltage-gated potassium channels Kv1.3 and Kv1.5 in human gliomas.	KCNA3 KCNA5	1.64e-06	2	45	2	12850541
Pubmed	Voltage-dependent potassium channels Kv1.3 and Kv1.5 in human fetus.	KCNA3 KCNA5	1.64e-06	2	45	2	20798505
Pubmed	Protein kinase Cepsilon may act as EGF-inducible scaffold protein for phospholipase Cgamma1.	PRKCE PLCG1	1.64e-06	2	45	2	17561374
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	SLTM ANKRD11 BEND3 CWC22 ATP2A1 SRSF9 RBM10 ZC3H13 YLPM1	3.09e-06	954	45	9	36373674
Pubmed	Genome-wide association study of opioid dependence: multiple associations mapped to calcium and potassium pathways.	KCNG2 KCNC1	4.91e-06	3	45	2	24143882
Pubmed	Megencephaly: a new mouse mutation on chromosome 6 that causes hypertrophy of the brain.	KCNA1 KCNA5	4.91e-06	3	45	2	8995755
Pubmed	Control of voltage-gated K+ channel permeability to NMDG+ by a residue at the outer pore.	KCNA5 KCNC1	4.91e-06	3	45	2	19332619
Pubmed	Caveolin interaction governs Kv1.3 lipid raft targeting.	KCNA3 KCNA5	4.91e-06	3	45	2	26931497
Pubmed	Cloning, sequence and chromosomal localization of MK6, a murine potassium channel gene.	KCNA1 KCNA6	4.91e-06	3	45	2	1285906
Pubmed	Potassium channel regulator KCNRG regulates surface expression of Shaker-type potassium channels.	KCNA1 KCNA4	4.91e-06	3	45	2	19968958
Pubmed	Clinical spectrum of voltage-gated potassium channel autoimmunity.	KCNA1 KCNA6	4.91e-06	3	45	2	18474843
Pubmed	Seizures and reduced life span in mice lacking the potassium channel subunit Kv1.2, but hypoexcitability and enlarged Kv1 currents in auditory neurons.	KCNA1 KCNA6	4.91e-06	3	45	2	17634333
Pubmed	A discrete amino terminal domain of Kv1.5 and Kv1.4 potassium channels interacts with the spectrin repeats of alpha-actinin-2.	KCNA4 KCNA5	4.91e-06	3	45	2	11389904
Pubmed	Human potassium channel genes: Molecular cloning and functional expression.	KCNA1 KCNA4	4.91e-06	3	45	2	19912772
Pubmed	Mutations in the KCNA1 gene associated with episodic ataxia type-1 syndrome impair heteromeric voltage-gated K(+) channel function.	KCNA1 KCNA4	4.91e-06	3	45	2	10428758
Pubmed	Potassium Channels Kv1.3 and Kir2.1 But Not Kv1.5 Contribute to BV2 Cell Line and Primary Microglial Migration.	KCNA3 KCNA5	4.91e-06	3	45	2	33669857
Pubmed	A family of three mouse potassium channel genes with intronless coding regions.	KCNA1 KCNA3	4.91e-06	3	45	2	2305265
Pubmed	Impaired OTUD7A-dependent Ankyrin regulation mediates neuronal dysfunction in mouse and human models of the 15q13.3 microdeletion syndrome.	KCNA1 KCNA3 KCNA4 KCNA6 GRM7	5.63e-06	197	45	5	36604605
Pubmed	Rescue of neuropsychiatric phenotypes in a mouse model of 16p11.2 duplication syndrome by genetic correction of an epilepsy network hub.	DPP6 KCNA1 KCNA3 GRM7 GNA13	8.61e-06	215	45	5	36808153
Pubmed	Kv1.5 association modifies Kv1.3 traffic and membrane localization.	KCNA3 KCNA5	9.81e-06	4	45	2	18218624
Pubmed	Incretin-stimulated interaction between β-cell Kv1.5 and Kvβ2 channel proteins involves acetylation/deacetylation by CBP/SirT1.	KCNA4 KCNA5	9.81e-06	4	45	2	23390957
Pubmed	KCNE4 is an inhibitory subunit to Kv1.1 and Kv1.3 potassium channels.	KCNA1 KCNA3	9.81e-06	4	45	2	12944270
Pubmed	Role of phospholipase Cgamma-induced activation of protein kinase Cepsilon (PKCepsilon) and PKCbetaI in epidermal growth factor-mediated protection of tight junctions from acetaldehyde in Caco-2 cell monolayers.	PRKCE PLCG1	9.81e-06	4	45	2	17991733
Pubmed	Modulation of voltage-dependent and inward rectifier potassium channels by 15-epi-lipoxin-A4 in activated murine macrophages: implications in innate immunity.	KCNA3 KCNA5	9.81e-06	4	45	2	24249731
Pubmed	K+ current diversity is produced by an extended gene family conserved in Drosophila and mouse.	KCNA1 KCNA3	1.63e-05	5	45	2	2333511
Pubmed	A mechanism for combinatorial regulation of electrical activity: Potassium channel subunits capable of functioning as Src homology 3-dependent adaptors.	KCNA4 KCNA5	1.63e-05	5	45	2	11149959
Pubmed	SAP97 increases Kv1.5 currents through an indirect N-terminal mechanism.	KCNA4 KCNA5	1.63e-05	5	45	2	12860415
Pubmed	Galpha12 and galpha13 are phosphorylated during platelet activation.	PRKCE GNA13	1.63e-05	5	45	2	8824244
Pubmed	Protein kinase C (PKC) activity regulates functional effects of Kvβ1.3 subunit on KV1.5 channels: identification of a cardiac Kv1.5 channelosome.	KCNA3 KCNA5	2.45e-05	6	45	2	22547057
Pubmed	Association of p62, a multifunctional SH2- and SH3-domain-binding protein, with src family tyrosine kinases, Grb2, and phospholipase C gamma-1.	PLCG1 KCNA1	2.45e-05	6	45	2	7799925
Pubmed	Targeted deletion of kcne2 impairs ventricular repolarization via disruption of I(K,slow1) and I(to,f).	KCNA4 KCNA5	2.45e-05	6	45	2	18603586
Pubmed	Math5 expression and function in the central auditory system.	KCNA1 KCNC1	3.42e-05	7	45	2	17977745
Pubmed	Postsynaptic density-93 clusters Kv1 channels at axon initial segments independently of Caspr2.	KCNA1 KCNA4	3.42e-05	7	45	2	18509034
Pubmed	Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.	PRKCE KCNA3 KCNA4 KCNA5 KCNA10 SGK1 KAT6A	3.96e-05	730	45	7	34857952
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	SLTM LSR AKAP8 SRSF9 GNA13 RBM10 UGGT1 YLPM1	4.50e-05	1024	45	8	24711643
Pubmed	The cellular EJC interactome reveals higher-order mRNP structure and an EJC-SR protein nexus.	CWC22 SRSF9 RBM10 ZC3H13	6.86e-05	169	45	4	23084401
Pubmed	An inducible CRISPR/Cas9 screen identifies DTX2 as a transcriptional regulator of human telomerase.	LSR AKAP8 RBM10 YLPM1	8.76e-05	180	45	4	35198878
Pubmed	Selectivity and promiscuity of the first and second PDZ domains of PSD-95 and synapse-associated protein 102.	KCNA1 KCNA4	1.07e-04	12	45	2	11937501
Pubmed	Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition.	FBXO38 PRKCE KCNA5 KCNA6 SGK1	1.17e-04	372	45	5	22939624
Pubmed	CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality.	BEND3 AKAP8 SRSF9 RBM10 ZC3H13 YLPM1	1.24e-04	605	45	6	28977666
Pubmed	EGF-stimulated signaling by means of PI3K, PLCgamma1, and PKC isozymes regulates branching morphogenesis of the fetal mouse submandibular gland.	PRKCE PLCG1	1.27e-04	13	45	2	12761849
Pubmed	TNIP2 is a Hub Protein in the NF-κB Network with Both Protein and RNA Mediated Interactions.	ANKRD11 LSR AKAP8 SRSF9 ZC3H13 CRTAP YLPM1	1.70e-04	922	45	7	27609421
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	SLTM BEND3 ZSWIM8 ZC3H13 UGGT1 YLPM1	1.87e-04	653	45	6	22586326
Pubmed	ZZW-115-dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents.	CWC22 SRSF9 RBM10 UGGT1 CRTAP YLPM1	1.98e-04	660	45	6	32780723
Pubmed	Synergistic gene interactions control the induction of the mitochondrial uncoupling protein (Ucp1) gene in white fat tissue.	KCNA4 KCNA10	2.20e-04	17	45	2	10931824
Pubmed	Comparative analysis of genes downstream of the Hoxd cluster in developing digits and external genitalia.	LSR SGK1	2.20e-04	17	45	2	15944189
Pubmed	A method to identify cDNAs based on localization of green fluorescent protein fusion products.	KAT6A YLPM1	2.20e-04	17	45	2	10716735
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	SLTM ANKRD11 BEND3 AKAP8 SRSF9 RBM10 ZC3H13 YLPM1	2.27e-04	1294	45	8	30804502
Pubmed	Interactome analyses revealed that the U1 snRNP machinery overlaps extensively with the RNAP II machinery and contains multiple ALS/SMA-causative proteins.	SLTM AKAP8 SRSF9 RBM10	2.81e-04	244	45	4	29884807
Pubmed	SETD1A Methyltransferase Is Physically and Functionally Linked to the DNA Damage Repair Protein RAD18.	CWC22 RBM10 ZC3H13 CRTAP	3.13e-04	251	45	4	31076518
Pubmed	Long-term potentiation modulates synaptic phosphorylation networks and reshapes the structure of the postsynaptic interactome.	PRKCE KCNA1 KCNA3 KCNA4	3.13e-04	251	45	4	27507650
Pubmed	Interaction proteomics of canonical Caspr2 (CNTNAP2) reveals the presence of two Caspr2 isoforms with overlapping interactomes.	KCNA1 KCNA6	3.38e-04	21	45	2	25707359
Pubmed	Peptidic degron in EID1 is recognized by an SCF E3 ligase complex containing the orphan F-box protein FBXO21.	RASA3 EID2	3.72e-04	22	45	2	26631746
Pubmed	Hepatic Glucocorticoid Receptor Plays a Greater Role Than Adipose GR in Metabolic Syndrome Despite Renal Compensation.	SGK1 GYS2	4.44e-04	24	45	2	27754788
Pubmed	Patterned expression of ion channel genes in mouse dorsal raphe nucleus determined with the Allen Mouse Brain Atlas.	KCNA4 CLCN6	4.44e-04	24	45	2	22534482
Pubmed	Release of calcium from inositol 1,4,5-trisphosphate receptor-regulated stores by HIV-1 Tat regulates TNF-alpha production in human macrophages.	PRKCE PLCG1	4.44e-04	24	45	2	10843712
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	SLTM AKAP8 CWC22 SRSF9 RBM10 ZC3H13 YLPM1	4.47e-04	1082	45	7	38697112
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	FBXO38 AKAP8 SRSF9 RBM10 ZC3H13 YLPM1	4.63e-04	774	45	6	15302935
Pubmed	The functional interactome landscape of the human histone deacetylase family.	ANKRD11 BEND3 AKAP8 YLPM1	5.32e-04	289	45	4	23752268
Pubmed	Mechanism of HIV-1-TAT induction of interleukin-1beta from human monocytes: Involvement of the phospholipase C/protein kinase C signaling cascade.	PRKCE PLCG1	5.63e-04	27	45	2	20336759
Pubmed	Large-scale interaction profiling of PDZ domains through proteomic peptide-phage display using human and viral phage peptidomes.	KCNA4 KCNA5	5.63e-04	27	45	2	24550280
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	SLTM LSR PLCG1 AJUBA RBM10 ZC3H13	5.81e-04	808	45	6	20412781
Pubmed	Systematic Analysis of Human Protein Phosphatase Interactions and Dynamics.	AKAP8 DUSP21 RASA3 STRIP2 YLPM1	8.46e-04	573	45	5	28330616
Pubmed	LKB1 deletion causes early changes in atrial channel expression and electrophysiology prior to atrial fibrillation.	KCNA4 KCNA5	8.94e-04	34	45	2	26378152
Pubmed	HIV-1 Vpr induces cell cycle arrest and enhances viral gene expression by depleting CCDC137.	SLTM RBM10 YLPM1	9.40e-04	148	45	3	32538781
Interaction	KCNAB2 interactions	DPP6 KCNA3 KCNA4 KCNA5 KCNA6 KCNA10	4.91e-09	62	45	6	int:KCNAB2
Interaction	DOLK interactions	KCNA1 KCNA3 KCNA5 KCNA6 KCNA10	1.41e-07	55	45	5	int:DOLK
Interaction	KCNA1 interactions	KCNA1 KCNA3 KCNA4 KCNA10	1.08e-06	35	45	4	int:KCNA1
Interaction	DHX40 interactions	SLTM ANKRD11 FBXO38 BEND3 AKAP8 ZC3H13 YLPM1	1.23e-06	249	45	7	int:DHX40
Interaction	KCNA2 interactions	KCNA1 KCNA3 KCNA4 KCNA5 KCNA10	8.48e-06	125	45	5	int:KCNA2
Interaction	KCNA4 interactions	KCNA1 KCNA3 KCNA4 KCNA5	1.59e-05	68	45	4	int:KCNA4
Interaction	GOLM1 interactions	KCNA4 KCNA5 KCNA6 KCNA10 ATP2A1	1.74e-05	145	45	5	int:GOLM1
Interaction	DLG4 interactions	PRKCE KCNA1 KCNA3 KCNA4 KCNA5 KCNA6 GRM7	5.68e-05	449	45	7	int:DLG4
Interaction	KCNC4 interactions	PRKCE KCNA3 KCNC1	7.67e-05	37	45	3	int:KCNC4
Interaction	SNRPA interactions	SLTM AKAP8 CWC22 SRSF9 RBM10 CRTAP YLPM1	8.86e-05	482	45	7	int:SNRPA
Interaction	ANKRD50 interactions	SLTM KCNA3 ZC3H13 YLPM1	9.81e-05	108	45	4	int:ANKRD50
Interaction	SSRP1 interactions	SLTM ANKRD11 AKAP8 SRSF9 RBM10 ZC3H13 KAT6A YLPM1	1.21e-04	685	45	8	int:SSRP1
Interaction	PRRT2 interactions	DPP6 KCNA1 KCNA3 GRM7 GNA13	1.27e-04	220	45	5	int:PRRT2
Interaction	CPSF6 interactions	SLTM AKAP8 CWC22 SRSF9 RBM10 CRTAP YLPM1	1.52e-04	526	45	7	int:CPSF6
Interaction	KCNRG interactions	KCNA1 KCNA4	1.74e-04	9	45	2	int:KCNRG
Interaction	ZFP64 interactions	KCNA4 RBM10 KAT6A	1.78e-04	49	45	3	int:ZFP64
Interaction	DLG1 interactions	KCNA1 KCNA3 KCNA4 KCNA5 KCNC1	1.90e-04	240	45	5	int:DLG1
Interaction	UQCR11 interactions	SLTM ZC3H13 YLPM1	2.25e-04	53	45	3	int:UQCR11
Interaction	SAA1 interactions	SLTM ZC3H13 YLPM1	2.38e-04	54	45	3	int:SAA1
GeneFamily	Potassium voltage-gated channels	KCNG2 KCNA1 KCNA3 KCNA4 KCNA5 KCNA6 KCNA10 KCNC1	7.88e-15	40	36	8	274
Coexpression	GSE40273_XBP1_KO_VS_WT_TREG_DN	GPR137B LOXL3 CWC22 EID2 SMYD2	2.29e-05	199	45	5	M9124
Coexpression	GSE7460_TCONV_VS_TREG_THYMUS_UP	ANKRD11 GPR137B CYP2S1 GRM7 SGK1	2.35e-05	200	45	5	M5675
ToppCell	droplet-Bladder-BLADDER-1m-Epithelial-endothelial_cell\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCNA1 KCNA4 KCNA6 METRN FAT3	1.01e-06	179	45	5	c7c74e26bbf86c5326ee38bac7de111d5414f46b
ToppCell	TCGA-Stomach-Solid_Tissue_Normal-Stomach_normal_tissue-Stomach_normal_tissue-7\|TCGA-Stomach / Sample_Type by Project: Shred V9	DPP6 KCNA1 KCNA5 FAT3	2.15e-05	162	45	4	b115b5799137122bd60696f8ae2aebadad6cd044
ToppCell	E18.5-samps-Mesenchymal-Pericyte\|E18.5-samps / Age Group, Lineage, Cell class and subclass	LOXL3 KCNA5 KCNA6 AJUBA	3.25e-05	180	45	4	0b1d370db64862fe1c7ea0ffaf06d03ec82e6e70
ToppCell	facs-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l25-31\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LOXL3 KCNA1 KCNA6 CLCN6	3.39e-05	182	45	4	a1c0e4090a9e7aa4941a40c817d178de144888b6
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-4M-Neuronal-ventral_progenitors_and_neurons_1\|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.	DPP6 KCNA1 GRM7 FAT3	4.01e-05	190	45	4	6e92c78799f34b31d098854503c796edb0dc7f80
ToppCell	COPD-Myeloid-cDC2\|World / Disease state, Lineage and Cell class	GPR137B CYP2S1 SGK1 GNA13	4.09e-05	191	45	4	4e4887175200a57e1b041f2f131e3df774df3509
ToppCell	COPD-Myeloid-cDC2\|COPD / Disease state, Lineage and Cell class	GPR137B CYP2S1 SGK1 GNA13	4.09e-05	191	45	4	2af6e4a6bd1f2193ece2131c3b7d976dd23a6966
ToppCell	IPF-Myeloid-cDC2\|World / Disease state, Lineage and Cell class	GPR137B CYP2S1 SGK1 GNA13	4.09e-05	191	45	4	9fda87fb6bc5b8b6c0214ec909ebbc9f3f65319b
ToppCell	IPF-Myeloid-cDC2\|IPF / Disease state, Lineage and Cell class	GPR137B CYP2S1 SGK1 GNA13	4.18e-05	192	45	4	fe1de692fec48cba4a9bbc6eaa257260e8b4e800
ToppCell	CTRL-Myeloid-Monocyte_Macrophage\|CTRL / Disease state, Lineage and Cell class	CYP2S1 SGK1 GNA13 STRIP2	4.35e-05	194	45	4	927480f56cccd3940b689f3c40ee132fe3e63745
Drug	digitoxigenine	KCNA1 KCNA3 KCNA4 KCNA5 KCNA6 KCNA10 KCNC1	7.84e-12	51	45	7	CID000008932
Drug	pyraclofos	KCNG2 KCNA1 KCNA3 KCNA4 KCNA5 KCNA6 KCNA10 KCNC1	3.15e-11	106	45	8	CID000093460
Drug	4-AP	KCNG2 PRKCE KCNA1 KCNA3 KCNA4 KCNA5 KCNA6 KCNA10 KCNC1 GRM7	6.60e-11	258	45	10	CID000001727
Drug	tetrapentylammonium	KCNA1 KCNA4 KCNA5 KCNA6 KCNC1	1.46e-10	17	45	5	CID000017248
Drug	AC1L1B9H	PRKCE KCNA1 KCNA3 KCNA4 KCNA5 KCNA6 KCNC1	1.72e-10	78	45	7	CID000001341
Drug	potassium	KCNG2 DPP6 PRKCE PLCG1 KCNA1 KCNA3 KCNA4 KCNA5 KCNA6 KCNA10 CLCN6 KCNC1 GRM7 ATP2A1 SGK1	4.40e-10	1008	45	15	CID000000813
Drug	diazoxide	KCNG2 PRKCE KCNA1 KCNA3 KCNA4 KCNA5 KCNA6 KCNA10 KCNC1	5.39e-10	227	45	9	CID000003019
Drug	tetraethylammonium	KCNG2 PRKCE KCNA1 KCNA3 KCNA4 KCNA5 KCNA6 KCNA10 KCNC1	7.60e-10	236	45	9	CID000005413
Drug	flecainide	DPP6 KCNA1 KCNA4 KCNA5 KCNA6 KCNC1	5.48e-09	71	45	6	CID000003355
Drug	Psora-4	KCNA1 KCNA4 KCNA5 KCNC1	9.39e-09	13	45	4	CID006603977
Drug	quindine	KCNA1 KCNA3 KCNA4 KCNA5 KCNA6 KCNA10 KCNC1 ATP2A1	1.02e-08	219	45	8	CID000001065
Drug	barium	PRKCE KCNA1 KCNA3 KCNA5 KCNA6 KCNA10 KCNC1	1.57e-08	148	45	7	CID000104810
Drug	verapamil	KCNG2 PRKCE KCNA1 KCNA3 KCNA4 KCNA5 KCNA6 KCNA10 KCNC1 ATP2A1	3.16e-08	490	45	10	CID000002520
Drug	AC1NPPZW	KCNA1 KCNA3 KCNA4 KCNA5 KCNA6 KCNC1	5.22e-08	103	45	6	CID005183170
Drug	acetazolamide	KCNA1 KCNA3 KCNA4 KCNA5 KCNA6 ATP2A1	6.56e-08	107	45	6	CID000001986
Drug	E 4031	KCNA1 KCNA3 KCNA5 KCNA6 KCNC1	7.06e-08	54	45	5	CID000003184
Drug	CID10948590	KCNA1 KCNA5 KCNA6	1.44e-07	6	45	3	CID010948590
Drug	clofilium	KCNA1 KCNA3 KCNA4 KCNA5 KCNA6	3.49e-07	74	45	5	CID000002798
Drug	LY97241	KCNA1 KCNA4 KCNA5	6.01e-07	9	45	3	CID000175064
Drug	doyle	PLCG1 KCNA1 KCNA3 KCNA4 KCNA6	8.32e-07	88	45	5	CID000002245
Drug	NSC618487	PRKCE PLCG1 KCNA1 KCNA3 KCNA4 KCNA5 KCNA6 GRM7 ATP2A1 GYS2 CRTAP	1.46e-06	933	45	11	CID000005279
Drug	AC1Q646P	KCNA1 KCNA3 KCNA5 KCNA6	2.23e-06	47	45	4	CID000005673
Drug	LS-63783	PRKCE PLCG1 KCNA1 CYP2S1 KCNA4 KCNA5 KCNA6 CLCN6 KCNC1 GYS2	2.96e-06	804	45	10	CID000000231
Drug	Gr-94800	KCNA1 KCNA4 KCNA5	3.97e-06	16	45	3	CID005487475
Drug	diaminopropionic acid	KCNA1 KCNA3 KCNA4 KCNA6	6.40e-06	61	45	4	CID000000364
Drug	1 sulfonylurea	KCNA1 KCNA4 KCNA5 KCNA6 GYS2	9.09e-06	143	45	5	CID011819083
Drug	glibenclamide	PRKCE KCNA1 KCNA3 KCNA5 KCNA6 CLCN6 GYS2	9.28e-06	382	45	7	CID000003488
Drug	sodium	PRKCE KCNA1 KCNA3 KCNA4 KCNA5 KCNA6 KCNC1 ATP2A1 SGK1 GNA13	1.22e-05	944	45	10	CID000000923
Drug	sotalol	KCNA1 KCNA3 KCNA5 KCNA6	1.31e-05	73	45	4	CID000005253
Drug	amiodarone	PLCG1 KCNA1 KCNA3 KCNA4 KCNA5	1.57e-05	160	45	5	CID000002156
Drug	1,N6-ethenoadenine	KCNA1 KCNA4 KCNA5 KCNA6	1.71e-05	78	45	4	CID000104994
Drug	propafenone	KCNG2 CYP2S1 KCNA4 KCNA5	4.20e-05	98	45	4	CID000004932
Drug	Indapamide [26807-65-8]; Down 200; 10.6uM; MCF7; HT_HG-U133A	FBXO38 CLCN6 GRM7 KAT6A YLPM1	4.46e-05	199	45	5	2322_DN
Drug	gallamine	KCNA1 KCNA3 KCNC1	4.52e-05	35	45	3	CID000003450
Drug	reduced haloperidol	KCNA1 KCNA4 KCNA5	5.35e-05	37	45	3	CID000119265
Drug	Potassium	KCNA5 KCNA10 KCNC1 SGK1	5.71e-05	106	45	4	ctd:D011188
Drug	3,4-diaminopyridine	KCNA3 KCNA5 KCNA6	5.80e-05	38	45	3	CID000005918
Drug	phosphine oxide	PRKCE KCNA5 KCNC1 GRM7	5.92e-05	107	45	4	CID000166931
Drug	C09179	PRKCE KCNA3 KCNC1	6.27e-05	39	45	3	CID000442082
Drug	5-(4-phenoxybutoxy)psoralen	KCNA5 KCNC1	7.97e-05	7	45	2	CID011302540
Drug	N-arachidonoylethanolamine	PRKCE KCNA1 KCNA4 KCNA5 KCNA6	8.15e-05	226	45	5	CID000002185
Drug	eye gene	PRKCE LOXL3 PLCG1 KCNC1 ATP2A1 GYS2	8.31e-05	369	45	6	CID000004782
Drug	AC1OAGFB	PRKCE PLCG1 KCNA1 KCNA4 KCNA5 AJUBA RASA3	8.34e-05	539	45	7	CID006857345
Drug	NSC122429	KCNA3 KCNA5	1.06e-04	8	45	2	CID000275537
Drug	guanidinium	KCNA1 KCNA4 UROD KCNA5 KCNA6	1.19e-04	245	45	5	CID000003520
Drug	8-bromoadenosine	PRKCE KCNA1 KCNA4 KCNA5	1.38e-04	133	45	4	CID000096544
Drug	benzylamine	LOXL3 KCNA1 UROD	1.49e-04	52	45	3	CID000007504
Drug	nifedipine	PRKCE CYP2S1 UROD KCNA5 GRM7 ATP2A1	1.58e-04	415	45	6	CID000004485
Drug	AC1L1O6Q	PRKCE PLCG1 KCNA3 KCNA4	1.72e-04	141	45	4	CID000058035
Drug	clotrimazole	KCNA3 UROD KCNA5 ATP2A1	1.82e-04	143	45	4	CID000002812
Drug	tetradotoxin	PRKCE KCNA1 KCNA4 KCNA6 GRM7 ATP2A1	1.87e-04	428	45	6	CID000020382
Drug	12 p	KCNA1 KCNA4 KCNA5 KCNA6 KAT6A	2.01e-04	274	45	5	CID000081248
Drug	melatonin	PRKCE CYP2S1 KCNA3 UROD GRM7 KAT6A	2.25e-04	443	45	6	CID000000896
Drug	rubidium	KCNA4 KCNA5 KCNC1	2.40e-04	61	45	3	CID000105153
Drug	paracrystals	PRKCE UROD KCNA5 CRTAP	2.86e-04	161	45	4	CID000004685
Drug	2,5-hexanediol	KCNA1 KCNA4	2.94e-04	13	45	2	CID000018049
Disease	epilepsy (implicated_via_orthology)	KCNA1 KCNA3 KCNA4 KCNA5 KCNA6 KCNA10	1.77e-07	163	45	6	DOID:1826 (implicated_via_orthology)
Disease	4-hydroxyhippurate measurement	DPP6 KCNA1	1.36e-05	4	45	2	EFO_0021508
Disease	response to isoquinoline alkaloid	KCNG2 KCNC1	2.27e-05	5	45	2	GO_0014072
Disease	response to angiotensin-converting enzyme inhibitor, Cough	KCNA1 KCNA5 GYS2	4.81e-05	46	45	3	EFO_0005325, HP_0012735
Disease	PCSK9 protein measurement	KCNA1 KCNA5	7.22e-04	26	45	2	EFO_0006899
Disease	conduct disorder	KCNA1 KCNA5	1.03e-03	31	45	2	EFO_0004216
Disease	response to allopurinol, uric acid measurement	KCNA1 KCNA5	1.10e-03	32	45	2	EFO_0004761, EFO_0006337
Disease	colorectal adenoma	GRM7 FAT3	1.17e-03	33	45	2	EFO_0005406
Disease	panic disorder	KCNA3 GRM7	1.17e-03	33	45	2	EFO_0004262
Disease	retinal detachment, retinal break	FAT3 CRTAP	1.31e-03	35	45	2	EFO_0005773, EFO_0010698
Disease	age at onset, Myopia	DPP6 KCNA4 GRM7	1.56e-03	150	45	3	EFO_0004847, HP_0000545
Disease	metachronous colorectal adenoma	KCNA5 FAT3	2.16e-03	45	45	2	EFO_0803377
Disease	Diffuse Large B-Cell Lymphoma	SGK1 GNA13	3.21e-03	55	45	2	C0079744
Disease	CCL5 measurement	KCNA4 AKAP8	4.32e-03	64	45	2	EFO_0005117

Protein segments in the cluster

Peptide	Gene	Start	Entry
DSRAREKRDYREPFF	ANKRD11	891	Q6UB99
DRESSFRFQPFESYD	AKAP8	121	O43823
DAERNQRGSFEAPRY	AJUBA	71	Q96IF1
YIVDRRFRSPDDSCN	GYS2	551	P54840
FVARNYLEDPEDERR	ATP2A1	986	O14983
FPRDGDYRDQDYRTE	RBM10	96	P98175
EAAAKRFQDDPDVRY	RASA3	461	Q14644
TSYAINPERFREEFE	BEND3	671	Q5T5X7
RYLPEFRETRAAQDF	UROD	41	P06132
DAFSEEANRRFERYP	LOXL3	731	P58215
LRNEYFFDRNRPSFD	KCNA1	76	Q09470
CAPRFQEFRRAYEAA	METRN	266	Q9UJH8
SRKFDEPRSRFYAAE	PRKCE	501	Q02156
QERSPRDRDYFDYSR	CWC22	36	Q9HCG8
EFNPDRFLDADGRFR	CYP2S1	411	Q96SQ9
DYDVSRDEFFFDRSP	KCNG2	61	Q9UJ96
RDEFFFDRSPCAFRA	KCNG2	66	Q9UJ96
EYFFDRNRPSFDAIL	KCNA3	146	P22001
FDQRAREEFRPTIYS	GNA13	76	Q14344
LRAAEPNSFARYDFE	FBXO38	1111	Q6PIJ6
RNEYFFDRNRPSFDG	KCNA10	126	Q16322
ENELFPREYFRRLSS	KAT6A	1076	Q92794
QFNFPYFRSDRDKRD	CLCN6	226	P51797
FDPLRNEYFFDRNRP	KCNA5	156	P22460
FFDPLRNEYFFDRNR	KCNA6	76	P17658
RNEYFFDRNRPSFDA	KCNA6	81	P17658
FDYDPRADEFFFDRH	KCNC1	46	P48547
AQYERYSFRSFPRDE	CRTAP	26	O75718
YRAFAFDRDEGPNAE	FAT3	1276	Q8TDW7
RAREAAFDAEYQRNP	EID2	186	Q8N6I1
RFLDRPDFFDYPDSD	FIMP	61	Q96LL3
STAPELSDDRRYDFF	GRM7	181	Q14831
LSDDRRYDFFSRVVP	GRM7	186	Q14831
RPRFQYQARSDGDEE	DPP6	66	P42658
ARDSRLYDFFDPIAD	DUSP21	76	Q9H596
RDDLYDQDDSRDFPR	LSR	531	Q86X29
RSYFFDNPRRYDSDD	GPR137B	336	O60478
FVRFEDPRDAEDAIY	SRSF9	56	Q13242
IEAFNSRRYDRPQDS	STRIP2	771	Q9ULQ0
ERCFLEPRARFYAAE	SGK1	191	O00141
FERYPKNFSDSRRNE	SLTM	816	Q9NWH9
LDQDLPRARDFYRQF	MROH2B	1476	Q7Z745
TSRDFDRYQEDPAFR	PLCG1	86	P19174
YDRERDREPYFDRQS	YLPM1	1686	P49750
PADYDDFVNAIRSAR	ZSWIM8	1781	A7E2V4
PTEDRNDRLRDSYFF	SMYD2	246	Q9NRG4
DPRIEYQFFEDRHSA	UGGT1	961	Q9NYU2
DRYPERDNRDQARDS	ZC3H13	606	Q5T200
RNEYFFDRNRPSFDA	KCNA4	216	P22459