| Category | Name | IntersectionWithQuery | PValue | GenesInTerm | GenesInQuery | GenesInTermInQuery | ID |
|---|---|---|---|---|---|---|---|
| GeneOntologyMolecularFunction | GTPase activator activity | 1.79e-06 | 279 | 60 | 8 | GO:0005096 | |
| GeneOntologyMolecularFunction | voltage-gated calcium channel activity involved in regulation of cytosolic calcium levels | 2.14e-06 | 9 | 60 | 3 | GO:0099511 | |
| GeneOntologyMolecularFunction | voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels | 2.14e-06 | 9 | 60 | 3 | GO:0099626 | |
| GeneOntologyMolecularFunction | enzyme activator activity | TAOK2 ARHGAP42 VPS9D1 ARHGAP6 RASAL3 SYDE2 SH3BP1 ASAP3 NCF1C NCF1B ARHGEF15 | 3.50e-06 | 656 | 60 | 11 | GO:0008047 |
| GeneOntologyMolecularFunction | SH3 domain binding | 4.42e-06 | 143 | 60 | 6 | GO:0017124 | |
| GeneOntologyMolecularFunction | nucleoside-triphosphatase regulator activity | 1.31e-04 | 507 | 60 | 8 | GO:0060589 | |
| GeneOntologyMolecularFunction | GTPase regulator activity | 1.31e-04 | 507 | 60 | 8 | GO:0030695 | |
| GeneOntologyMolecularFunction | phosphatidylinositol-3,4-bisphosphate binding | 1.58e-04 | 35 | 60 | 3 | GO:0043325 | |
| GeneOntologyMolecularFunction | structural constituent of presynaptic active zone | 2.46e-04 | 8 | 60 | 2 | GO:0098882 | |
| GeneOntologyMolecularFunction | molecular function activator activity | TAOK2 ARHGAP42 VPS9D1 ARHGAP6 RASAL3 SYDE2 SH3BP1 ASAP3 NCF1C NCF1B ARHGEF15 SPX | 2.57e-04 | 1233 | 60 | 12 | GO:0140677 |
| GeneOntologyMolecularFunction | voltage-gated calcium channel activity | 3.57e-04 | 46 | 60 | 3 | GO:0005245 | |
| GeneOntologyMolecularFunction | superoxide-generating NADPH oxidase activator activity | 3.93e-04 | 10 | 60 | 2 | GO:0016176 | |
| GeneOntologyMolecularFunction | superoxide-generating NAD(P)H oxidase activity | 5.75e-04 | 12 | 60 | 2 | GO:0016175 | |
| GeneOntologyMolecularFunction | calcium channel activity | 6.13e-04 | 129 | 60 | 4 | GO:0005262 | |
| GeneOntologyMolecularFunction | high voltage-gated calcium channel activity | 7.89e-04 | 14 | 60 | 2 | GO:0008331 | |
| GeneOntologyMolecularFunction | calcium ion transmembrane transporter activity | 1.10e-03 | 151 | 60 | 4 | GO:0015085 | |
| GeneOntologyMolecularFunction | voltage-gated monoatomic cation channel activity | 1.13e-03 | 152 | 60 | 4 | GO:0022843 | |
| GeneOntologyMolecularFunction | protein domain specific binding | 1.13e-03 | 875 | 60 | 9 | GO:0019904 | |
| GeneOntologyMolecularFunction | oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor | 1.63e-03 | 20 | 60 | 2 | GO:0050664 | |
| GeneOntologyMolecularFunction | voltage-gated monoatomic ion channel activity | 2.19e-03 | 182 | 60 | 4 | GO:0005244 | |
| GeneOntologyMolecularFunction | voltage-gated channel activity | 2.28e-03 | 184 | 60 | 4 | GO:0022832 | |
| GeneOntologyMolecularFunction | phosphatidylinositol binding | 2.58e-03 | 316 | 60 | 5 | GO:0035091 | |
| GeneOntologyMolecularFunction | phosphatidylinositol-4,5-bisphosphate binding | 2.93e-03 | 95 | 60 | 3 | GO:0005546 | |
| GeneOntologyMolecularFunction | enzyme regulator activity | TAOK2 ARHGAP42 VPS9D1 ARHGAP6 RASAL3 SYDE2 SH3BP1 ASAP3 NCF1C NCF1B ARHGEF15 | 3.02e-03 | 1418 | 60 | 11 | GO:0030234 |
| GeneOntologyMolecularFunction | monoatomic cation channel activity | 3.66e-03 | 343 | 60 | 5 | GO:0005261 | |
| GeneOntologyMolecularFunction | phosphatidylinositol bisphosphate binding | 5.78e-03 | 121 | 60 | 3 | GO:1902936 | |
| GeneOntologyMolecularFunction | phospholipid binding | 5.94e-03 | 548 | 60 | 6 | GO:0005543 | |
| GeneOntologyMolecularFunction | structural constituent of synapse | 7.08e-03 | 42 | 60 | 2 | GO:0098918 | |
| GeneOntologyBiologicalProcess | regulation of calcium-dependent activation of synaptic vesicle fusion | 7.33e-07 | 7 | 58 | 3 | GO:0150037 | |
| GeneOntologyBiologicalProcess | positive regulation of synaptic vesicle fusion to presynaptic active zone membrane | 5.92e-06 | 13 | 58 | 3 | GO:0031632 | |
| GeneOntologyBiologicalProcess | positive regulation of synaptic vesicle membrane organization | 5.92e-06 | 13 | 58 | 3 | GO:1901634 | |
| GeneOntologyBiologicalProcess | calcium-dependent activation of synaptic vesicle fusion | 5.92e-06 | 13 | 58 | 3 | GO:0099502 | |
| GeneOntologyBiologicalProcess | signal release from synapse | 1.78e-05 | 195 | 58 | 6 | GO:0099643 | |
| GeneOntologyBiologicalProcess | neurotransmitter secretion | 1.78e-05 | 195 | 58 | 6 | GO:0007269 | |
| GeneOntologyBiologicalProcess | regulation of synaptic vesicle fusion to presynaptic active zone membrane | 2.33e-05 | 20 | 58 | 3 | GO:0031630 | |
| GeneOntologyBiologicalProcess | regulation of synaptic vesicle membrane organization | 2.33e-05 | 20 | 58 | 3 | GO:1901632 | |
| GeneOntologyBiologicalProcess | positive regulation of vesicle fusion | 2.33e-05 | 20 | 58 | 3 | GO:0031340 | |
| GeneOntologyBiologicalProcess | negative regulation of smooth muscle contraction | 3.13e-05 | 22 | 58 | 3 | GO:0045986 | |
| GeneOntologyBiologicalProcess | regulation of small GTPase mediated signal transduction | 3.98e-05 | 333 | 58 | 7 | GO:0051056 | |
| GeneOntologyBiologicalProcess | regulation of GTPase activity | 4.14e-05 | 335 | 58 | 7 | GO:0043087 | |
| GeneOntologyBiologicalProcess | positive regulation of GTPase activity | 6.24e-05 | 244 | 58 | 6 | GO:0043547 | |
| GeneOntologyBiologicalProcess | regulation of organelle organization | TAOK2 CACNA1B ARHGAP6 ERC1 G3BP2 SH3BP1 ASAP3 SPIRE1 RIMBP2 DYSF TERF2 ARHGEF15 DNM2 | 7.10e-05 | 1342 | 58 | 13 | GO:0033043 |
| GeneOntologyBiologicalProcess | regulation of smooth muscle contraction | 7.23e-05 | 79 | 58 | 4 | GO:0006940 | |
| GeneOntologyBiologicalProcess | positive regulation of clathrin-dependent endocytosis | 7.73e-05 | 5 | 58 | 2 | GO:2000370 | |
| GeneOntologyBiologicalProcess | neutrophil-mediated killing of gram-positive bacterium | 7.73e-05 | 5 | 58 | 2 | GO:0070946 | |
| GeneOntologyBiologicalProcess | neurotransmitter transport | 8.67e-05 | 259 | 58 | 6 | GO:0006836 | |
| GeneOntologyBiologicalProcess | synaptic vesicle fusion to presynaptic active zone membrane | 8.97e-05 | 31 | 58 | 3 | GO:0031629 | |
| GeneOntologyBiologicalProcess | vesicle fusion to plasma membrane | 9.88e-05 | 32 | 58 | 3 | GO:0099500 | |
| GeneOntologyBiologicalProcess | small GTPase-mediated signal transduction | 1.24e-04 | 538 | 58 | 8 | GO:0007264 | |
| GeneOntologyBiologicalProcess | negative regulation of muscle contraction | 1.30e-04 | 35 | 58 | 3 | GO:0045932 | |
| GeneOntologyBiologicalProcess | regulation of vesicle fusion | 1.30e-04 | 35 | 58 | 3 | GO:0031338 | |
| GeneOntologyBiologicalProcess | synaptic vesicle membrane organization | 1.41e-04 | 36 | 58 | 3 | GO:0048499 | |
| GeneOntologyBiologicalProcess | neuromuscular synaptic transmission | 1.41e-04 | 36 | 58 | 3 | GO:0007274 | |
| GeneOntologyBiologicalProcess | NADP catabolic process | 1.62e-04 | 7 | 58 | 2 | GO:0006742 | |
| GeneOntologyBiologicalProcess | neutrophil-mediated killing of fungus | 1.62e-04 | 7 | 58 | 2 | GO:0070947 | |
| GeneOntologyBiologicalProcess | actin filament bundle assembly | 1.99e-04 | 191 | 58 | 5 | GO:0051017 | |
| GeneOntologyBiologicalProcess | actin filament bundle organization | 2.19e-04 | 195 | 58 | 5 | GO:0061572 | |
| GeneOntologyBiologicalProcess | regulation of muscle contraction | 2.58e-04 | 202 | 58 | 5 | GO:0006937 | |
| GeneOntologyBiologicalProcess | vesicle-mediated transport in synapse | 2.78e-04 | 321 | 58 | 6 | GO:0099003 | |
| GeneOntologyBiologicalProcess | regulation of neurotransmitter secretion | 3.40e-04 | 118 | 58 | 4 | GO:0046928 | |
| GeneOntologyBiologicalProcess | positive regulation of Wnt signaling pathway, planar cell polarity pathway | 3.45e-04 | 10 | 58 | 2 | GO:2000096 | |
| GeneOntologyBiologicalProcess | regulation of respiratory burst involved in inflammatory response | 4.21e-04 | 11 | 58 | 2 | GO:0060264 | |
| GeneOntologyBiologicalProcess | synaptic vesicle exocytosis | 4.23e-04 | 125 | 58 | 4 | GO:0016079 | |
| GeneOntologyBiologicalProcess | multicellular organismal response to stress | 4.36e-04 | 126 | 58 | 4 | GO:0033555 | |
| GeneOntologyBiologicalProcess | stress fiber assembly | 4.50e-04 | 127 | 58 | 4 | GO:0043149 | |
| GeneOntologyBiologicalProcess | contractile actin filament bundle assembly | 4.50e-04 | 127 | 58 | 4 | GO:0030038 | |
| GeneOntologyBiologicalProcess | regulation of vesicle-mediated transport | 5.27e-04 | 667 | 58 | 8 | GO:0060627 | |
| GeneOntologyBiologicalProcess | smooth muscle contraction | 5.35e-04 | 133 | 58 | 4 | GO:0006939 | |
| GeneOntologyBiologicalProcess | respiratory burst involved in inflammatory response | 5.94e-04 | 13 | 58 | 2 | GO:0002536 | |
| GeneOntologyBiologicalProcess | regulation of neurotransmitter transport | 6.67e-04 | 141 | 58 | 4 | GO:0051588 | |
| GeneOntologyBiologicalProcess | vesicle fusion | 6.85e-04 | 142 | 58 | 4 | GO:0006906 | |
| GeneOntologyBiologicalProcess | organelle membrane fusion | 7.22e-04 | 144 | 58 | 4 | GO:0090174 | |
| GeneOntologyBiologicalProcess | synaptic vesicle cycle | 8.71e-04 | 264 | 58 | 5 | GO:0099504 | |
| GeneOntologyBiologicalProcess | negative regulation of small GTPase mediated signal transduction | 8.90e-04 | 67 | 58 | 3 | GO:0051058 | |
| GeneOntologyBiologicalProcess | neutrophil-mediated killing of bacterium | 9.09e-04 | 16 | 58 | 2 | GO:0070944 | |
| GeneOntologyBiologicalProcess | regulation of system process | 9.84e-04 | 734 | 58 | 8 | GO:0044057 | |
| GeneOntologyBiologicalProcess | positive regulation of organelle organization | 1.10e-03 | 574 | 58 | 7 | GO:0010638 | |
| GeneOntologyBiologicalProcess | positive regulation of non-canonical Wnt signaling pathway | 1.16e-03 | 18 | 58 | 2 | GO:2000052 | |
| GeneOntologyBiologicalProcess | response to yeast | 1.16e-03 | 18 | 58 | 2 | GO:0001878 | |
| GeneOntologyBiologicalProcess | regulation of Wnt signaling pathway, planar cell polarity pathway | 1.29e-03 | 19 | 58 | 2 | GO:2000095 | |
| GeneOntologyBiologicalProcess | neutrophil-mediated killing of symbiont cell | 1.29e-03 | 19 | 58 | 2 | GO:0070943 | |
| GeneOntologyBiologicalProcess | regulation of actin filament-based process | 1.41e-03 | 438 | 58 | 6 | GO:0032970 | |
| GeneOntologyBiologicalProcess | respiratory burst involved in defense response | 1.43e-03 | 20 | 58 | 2 | GO:0002679 | |
| MousePheno | abnormal eye anterior chamber morphology | 7.64e-06 | 80 | 48 | 5 | MP:0005205 | |
| MousePheno | abnormal eye anterior chamber depth | 6.68e-05 | 64 | 48 | 4 | MP:0011960 | |
| MousePheno | abnormal behavioral response to alcohol | 7.31e-05 | 24 | 48 | 3 | MP:0020157 | |
| MousePheno | increased angiotensin I-converting enzyme activity | 1.72e-04 | 6 | 48 | 2 | MP:0003184 | |
| MousePheno | abnormal angiotensin I-converting enzyme activity | 1.72e-04 | 6 | 48 | 2 | MP:0013254 | |
| MousePheno | liver abscess | 2.40e-04 | 7 | 48 | 2 | MP:0003332 | |
| Domain | Rho_GTPase_activation_prot | 7.15e-06 | 88 | 57 | 5 | IPR008936 | |
| Domain | CCDC74_C | 9.15e-06 | 2 | 57 | 2 | PF14917 | |
| Domain | CCDC74 | 9.15e-06 | 2 | 57 | 2 | IPR033226 | |
| Domain | CCDC74_C | 9.15e-06 | 2 | 57 | 2 | IPR029422 | |
| Domain | RhoGAP | 3.81e-05 | 62 | 57 | 4 | SM00324 | |
| Domain | RhoGAP | 4.06e-05 | 63 | 57 | 4 | PF00620 | |
| Domain | RHOGAP | 4.32e-05 | 64 | 57 | 4 | PS50238 | |
| Domain | RhoGAP_dom | 4.32e-05 | 64 | 57 | 4 | IPR000198 | |
| Domain | - | 4.32e-05 | 64 | 57 | 4 | 1.10.555.10 | |
| Domain | VDCC_a1su_IQ | 1.90e-04 | 7 | 57 | 2 | IPR014873 | |
| Domain | GPHH | 1.90e-04 | 7 | 57 | 2 | PF16905 | |
| Domain | GPHH_dom | 1.90e-04 | 7 | 57 | 2 | IPR031649 | |
| Domain | Ca_chan_IQ | 1.90e-04 | 7 | 57 | 2 | SM01062 | |
| Domain | Ca_chan_IQ | 1.90e-04 | 7 | 57 | 2 | PF08763 | |
| Domain | PH_dom-like | 3.02e-04 | 426 | 57 | 7 | IPR011993 | |
| Domain | VDCCAlpha1 | 4.05e-04 | 10 | 57 | 2 | IPR002077 | |
| Domain | RmlC_Cupin | 1.07e-03 | 16 | 57 | 2 | IPR011051 | |
| Domain | - | 1.08e-03 | 148 | 57 | 4 | 2.60.40.150 | |
| Domain | - | 1.19e-03 | 391 | 57 | 6 | 2.30.29.30 | |
| Domain | BAR | 1.51e-03 | 19 | 57 | 2 | PS51021 | |
| Domain | PH | 1.57e-03 | 278 | 57 | 5 | SM00233 | |
| Domain | C2_dom | 1.58e-03 | 164 | 57 | 4 | IPR000008 | |
| Domain | PH_DOMAIN | 1.59e-03 | 279 | 57 | 5 | PS50003 | |
| Domain | PH_domain | 1.62e-03 | 280 | 57 | 5 | IPR001849 | |
| Domain | - | 3.77e-03 | 30 | 57 | 2 | 1.20.1270.60 | |
| Domain | AH/BAR-dom | 3.77e-03 | 30 | 57 | 2 | IPR027267 | |
| Domain | Ion_trans_dom | 5.10e-03 | 114 | 57 | 3 | IPR005821 | |
| Domain | Ion_trans | 5.10e-03 | 114 | 57 | 3 | PF00520 | |
| Domain | PH | 5.23e-03 | 229 | 57 | 4 | PF00169 | |
| Domain | C2 | 9.33e-03 | 142 | 57 | 3 | PS50004 | |
| Pathway | REACTOME_RAC1_GTPASE_CYCLE | 2.08e-05 | 175 | 46 | 6 | MM15599 | |
| Pathway | REACTOME_RAC3_GTPASE_CYCLE | 2.34e-04 | 93 | 46 | 4 | MM15609 | |
| Pathway | REACTOME_CROSS_PRESENTATION_OF_PARTICULATE_EXOGENOUS_ANTIGENS_PHAGOSOMES | 3.70e-04 | 9 | 46 | 2 | MM14524 | |
| Pathway | REACTOME_RHO_GTPASE_CYCLE | 5.07e-04 | 439 | 46 | 7 | MM15595 | |
| Pathway | KEGG_MEDICUS_REFERENCE_CA2_CAM_VGCC_RYR_SIGNALING_PATHWAY | 5.62e-04 | 11 | 46 | 2 | M47958 | |
| Pathway | REACTOME_PRESYNAPTIC_DEPOLARIZATION_AND_CALCIUM_CHANNEL_OPENING | 5.62e-04 | 11 | 46 | 2 | MM14498 | |
| Pathway | REACTOME_GAP_JUNCTION_DEGRADATION | 5.62e-04 | 11 | 46 | 2 | MM14732 | |
| Pathway | REACTOME_PRESYNAPTIC_DEPOLARIZATION_AND_CALCIUM_CHANNEL_OPENING | 5.62e-04 | 11 | 46 | 2 | M26913 | |
| Pathway | WP_SYNAPTIC_VESICLE_PATHWAY | 6.07e-04 | 51 | 46 | 3 | M39457 | |
| Pathway | REACTOME_GAP_JUNCTION_DEGRADATION | 6.73e-04 | 12 | 46 | 2 | M15243 | |
| Pubmed | 1.13e-07 | 6 | 63 | 3 | 19833721 | ||
| Pubmed | Rebuilding essential active zone functions within a synapse. | 1.97e-07 | 7 | 63 | 3 | 35176221 | |
| Pubmed | TAOK2 CACNA1A HCN4 ERC1 G3BP2 SH3BP1 RIMBP2 LMNB2 PRRC2A DNM2 PCNT | 1.15e-06 | 963 | 63 | 11 | 28671696 | |
| Pubmed | Proteins recruited by SH3 domains of Ruk/CIN85 adaptor identified by LC-MS/MS. | 1.60e-06 | 108 | 63 | 5 | 19531213 | |
| Pubmed | 2.03e-06 | 14 | 63 | 3 | 21228161 | ||
| Pubmed | 3.23e-06 | 2 | 63 | 2 | 26086043 | ||
| Pubmed | Stable respiratory activity requires both P/Q-type and N-type voltage-gated calcium channels. | 3.23e-06 | 2 | 63 | 2 | 23426690 | |
| Pubmed | 3.23e-06 | 2 | 63 | 2 | 38155373 | ||
| Pubmed | 3.23e-06 | 2 | 63 | 2 | 15050706 | ||
| Pubmed | CCDC74A/B are K-fiber crosslinkers required for chromosomal alignment. | 3.23e-06 | 2 | 63 | 2 | 31521166 | |
| Pubmed | 3.23e-06 | 2 | 63 | 2 | 23376566 | ||
| Pubmed | 9.68e-06 | 3 | 63 | 2 | 33705493 | ||
| Pubmed | 9.68e-06 | 3 | 63 | 2 | 18036262 | ||
| Pubmed | Inhibition of NADPH oxidase by apocynin attenuates progression of atherosclerosis. | 9.68e-06 | 3 | 63 | 2 | 23965970 | |
| Pubmed | Transient loss of resistance to pulmonary tuberculosis in p47(phox-/-) mice. | 9.68e-06 | 3 | 63 | 2 | 10678931 | |
| Pubmed | Colitis susceptibility in p47(phox-/-) mice is mediated by the microbiome. | 9.68e-06 | 3 | 63 | 2 | 27044504 | |
| Pubmed | 9.68e-06 | 3 | 63 | 2 | 17167081 | ||
| Pubmed | Mice lacking NCF1 exhibit reduced growth of implanted melanoma and carcinoma tumors. | 9.68e-06 | 3 | 63 | 2 | 24358335 | |
| Pubmed | 9.68e-06 | 3 | 63 | 2 | 10891396 | ||
| Pubmed | 9.68e-06 | 3 | 63 | 2 | 25474113 | ||
| Pubmed | NADPH oxidase in bone marrow-derived cells mediates pulmonary ischemia-reperfusion injury. | 9.68e-06 | 3 | 63 | 2 | 18787174 | |
| Pubmed | 9.68e-06 | 3 | 63 | 2 | 26209274 | ||
| Pubmed | 9.68e-06 | 3 | 63 | 2 | 24873968 | ||
| Pubmed | 9.68e-06 | 3 | 63 | 2 | 38996073 | ||
| Pubmed | 9.68e-06 | 3 | 63 | 2 | 22184329 | ||
| Pubmed | 9.68e-06 | 3 | 63 | 2 | 26455429 | ||
| Pubmed | 9.68e-06 | 3 | 63 | 2 | 15513930 | ||
| Pubmed | NADPH oxidase-derived free radicals are key oxidants in alcohol-induced liver disease. | 9.68e-06 | 3 | 63 | 2 | 11018074 | |
| Pubmed | 9.68e-06 | 3 | 63 | 2 | 15626477 | ||
| Pubmed | 9.68e-06 | 3 | 63 | 2 | 15033459 | ||
| Pubmed | Natural Loss-of-Function Mutations in Qa2 and NCF1 Cause the Spread of Mannan-Induced Psoriasis. | 9.68e-06 | 3 | 63 | 2 | 33545139 | |
| Pubmed | Small-molecule screen identifies reactive oxygen species as key regulators of neutrophil chemotaxis. | 9.68e-06 | 3 | 63 | 2 | 20142487 | |
| Pubmed | 9.68e-06 | 3 | 63 | 2 | 9116268 | ||
| Pubmed | 9.68e-06 | 3 | 63 | 2 | 20686129 | ||
| Pubmed | NCF1 gene and pseudogene pattern: association with parasitic infection and autoimmunity. | 9.68e-06 | 3 | 63 | 2 | 19077231 | |
| Pubmed | Neutrophil-derived ROS contribute to oxidative DNA damage induction by quartz particles. | 9.68e-06 | 3 | 63 | 2 | 20828610 | |
| Pubmed | 9.68e-06 | 3 | 63 | 2 | 20817944 | ||
| Pubmed | Angiotensin II induced catabolic effect and muscle atrophy are redox dependent. | 9.68e-06 | 3 | 63 | 2 | 21570954 | |
| Pubmed | p47(phox) contributes to albuminuria and kidney fibrosis in mice. | 9.68e-06 | 3 | 63 | 2 | 25565313 | |
| Pubmed | 9.68e-06 | 3 | 63 | 2 | 22319452 | ||
| Pubmed | 9.68e-06 | 3 | 63 | 2 | 16895801 | ||
| Pubmed | Role and cellular source of nicotinamide adenine dinucleotide phosphate oxidase in hepatic fibrosis. | 9.68e-06 | 3 | 63 | 2 | 20690191 | |
| Pubmed | 9.68e-06 | 3 | 63 | 2 | 16772302 | ||
| Pubmed | 9.68e-06 | 3 | 63 | 2 | 39357591 | ||
| Pubmed | 9.68e-06 | 3 | 63 | 2 | 32504071 | ||
| Pubmed | 9.68e-06 | 3 | 63 | 2 | 16280459 | ||
| Pubmed | 9.68e-06 | 3 | 63 | 2 | 29466725 | ||
| Pubmed | Defective tryptophan catabolism underlies inflammation in mouse chronic granulomatous disease. | 9.68e-06 | 3 | 63 | 2 | 18185592 | |
| Pubmed | 9.68e-06 | 3 | 63 | 2 | 12958309 | ||
| Pubmed | 9.68e-06 | 3 | 63 | 2 | 11435342 | ||
| Pubmed | 9.68e-06 | 3 | 63 | 2 | 31118934 | ||
| Pubmed | 9.68e-06 | 3 | 63 | 2 | 23482812 | ||
| Pubmed | 9.68e-06 | 3 | 63 | 2 | 36853827 | ||
| Pubmed | 9.68e-06 | 3 | 63 | 2 | 23024271 | ||
| Pubmed | 9.68e-06 | 3 | 63 | 2 | 16041040 | ||
| Pubmed | 9.68e-06 | 3 | 63 | 2 | 10085000 | ||
| Pubmed | 9.68e-06 | 3 | 63 | 2 | 10987289 | ||
| Pubmed | 9.68e-06 | 3 | 63 | 2 | 21253614 | ||
| Pubmed | 9.68e-06 | 3 | 63 | 2 | 21435178 | ||
| Pubmed | 9.68e-06 | 3 | 63 | 2 | 25873172 | ||
| Pubmed | 9.68e-06 | 3 | 63 | 2 | 15310853 | ||
| Pubmed | Intermittent hypoxia has organ-specific effects on oxidative stress. | 9.68e-06 | 3 | 63 | 2 | 18703411 | |
| Pubmed | 9.68e-06 | 3 | 63 | 2 | 29228045 | ||
| Pubmed | 9.68e-06 | 3 | 63 | 2 | 17307863 | ||
| Pubmed | 9.68e-06 | 3 | 63 | 2 | 31393787 | ||
| Pubmed | 9.68e-06 | 3 | 63 | 2 | 10725280 | ||
| Pubmed | 9.68e-06 | 3 | 63 | 2 | 22155727 | ||
| Pubmed | Ncf1 affects osteoclast formation but is not critical for postmenopausal bone loss. | 9.68e-06 | 3 | 63 | 2 | 27829407 | |
| Pubmed | Ncf1 Governs Immune Niches in the Lung to Mediate Pulmonary Inflammation in Mice. | 9.68e-06 | 3 | 63 | 2 | 34970267 | |
| Pubmed | Germ-free mice deficient of reactive oxygen species have increased arthritis susceptibility. | 9.68e-06 | 3 | 63 | 2 | 25689796 | |
| Pubmed | Mechanism of endoplasmic reticulum stress-induced vascular endothelial dysfunction. | 9.68e-06 | 3 | 63 | 2 | 24576409 | |
| Pubmed | 9.68e-06 | 3 | 63 | 2 | 22376231 | ||
| Pubmed | 9.68e-06 | 3 | 63 | 2 | 14993144 | ||
| Pubmed | 9.68e-06 | 3 | 63 | 2 | 23918780 | ||
| Pubmed | NADPH oxidase NOX2 mediates TLR2/6-dependent release of GM-CSF from endothelial cells. | 9.68e-06 | 3 | 63 | 2 | 28274989 | |
| Pubmed | 9.68e-06 | 3 | 63 | 2 | 26645958 | ||
| Pubmed | Distinct roles for Cav2.1-2.3 in activity-dependent synaptic dynamics. | 9.68e-06 | 3 | 63 | 2 | 24523520 | |
| Pubmed | 9.68e-06 | 3 | 63 | 2 | 22050439 | ||
| Pubmed | The vascular NADPH oxidase subunit p47phox is involved in redox-mediated gene expression. | 9.68e-06 | 3 | 63 | 2 | 12031896 | |
| Pubmed | Role of p47(phox) in vascular oxidative stress and hypertension caused by angiotensin II. | 9.68e-06 | 3 | 63 | 2 | 12364355 | |
| Pubmed | 9.68e-06 | 3 | 63 | 2 | 11249873 | ||
| Pubmed | Ankyrin-B regulates Cav2.1 and Cav2.2 channel expression and targeting. | 9.68e-06 | 3 | 63 | 2 | 24394417 | |
| Pubmed | 9.68e-06 | 3 | 63 | 2 | 15936744 | ||
| Pubmed | 9.68e-06 | 3 | 63 | 2 | 17220182 | ||
| Pubmed | NADPH oxidase promotes neutrophil extracellular trap formation in pulmonary aspergillosis. | 9.68e-06 | 3 | 63 | 2 | 24549323 | |
| Pubmed | 9.68e-06 | 3 | 63 | 2 | 25628043 | ||
| Pubmed | 9.68e-06 | 3 | 63 | 2 | 34557202 | ||
| Pubmed | 9.68e-06 | 3 | 63 | 2 | 28467721 | ||
| Pubmed | 9.68e-06 | 3 | 63 | 2 | 10670582 | ||
| Pubmed | NADPH oxidase deficiency regulates Th lineage commitment and modulates autoimmunity. | 9.68e-06 | 3 | 63 | 2 | 20881184 | |
| Pubmed | The p47phox mouse knock-out model of chronic granulomatous disease. | 9.68e-06 | 3 | 63 | 2 | 7650482 | |
| Pubmed | 9.68e-06 | 3 | 63 | 2 | 26528554 | ||
| Pubmed | The role of reactive oxygen species in immunopathogenesis of rheumatoid arthritis. | 9.68e-06 | 3 | 63 | 2 | 19052348 | |
| Pubmed | Disseminated trichosporonosis in a murine model of chronic granulomatous disease. | 9.68e-06 | 3 | 63 | 2 | 12868577 | |
| Pubmed | Molecular moieties masking Ca2+-dependent facilitation of voltage-gated Cav2.2 Ca2+ channels. | 9.68e-06 | 3 | 63 | 2 | 29208674 | |
| Pubmed | 9.68e-06 | 3 | 63 | 2 | 12560337 | ||
| Pubmed | Effect of early particulate air pollution exposure on obesity in mice: role of p47phox. | 9.68e-06 | 3 | 63 | 2 | 20864666 | |
| Pubmed | NADPH oxidase mediates striatal neuronal injury after transient global cerebral ischemia. | 9.68e-06 | 3 | 63 | 2 | 20859296 | |
| Pubmed | Reactive oxygen species delay control of lymphocytic choriomeningitis virus. | 9.68e-06 | 3 | 63 | 2 | 23328631 | |
| Pubmed | 9.68e-06 | 3 | 63 | 2 | 35276443 | ||
| Interaction | SH3KBP1 interactions | 4.12e-06 | 315 | 60 | 8 | int:SH3KBP1 | |
| Cytoband | Ensembl 112 genes in cytogenetic band chr15q24 | 6.47e-04 | 122 | 63 | 3 | chr15q24 | |
| Cytoband | 12p12.1 | 7.35e-04 | 29 | 63 | 2 | 12p12.1 | |
| GeneFamily | Rho GTPase activating proteins|BCH domain containing | 1.57e-04 | 50 | 38 | 3 | 721 | |
| GeneFamily | Calcium voltage-gated channel subunits | 1.35e-03 | 26 | 38 | 2 | 253 | |
| CoexpressionAtlas | FacebaseRNAseq_e8.5_Non-Floor Plate Neural Epithelium_top-relative-expression-ranked_2500_k-means-cluster#1 | VPS9D1 ARHGAP6 CRTC3 RASAL3 CSF2RB PRICKLE3 LOXL1 CSPG4 PLEKHA4 ASAP3 C8G MOBP | 7.43e-06 | 878 | 62 | 12 | Facebase_RNAseq_e8.5_Non-Floor Plate Neural Epithelium_2500_K1 |
| CoexpressionAtlas | FacebaseRNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_1000_k-means-cluster#4 | 2.87e-05 | 204 | 62 | 6 | Facebase_RNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_1000_K4 | |
| CoexpressionAtlas | FacebaseRNAseq_ratio_e10.5_MandibularArch_vs_MaxillaryArch_top-relative-expression-ranked_2500_k-means-cluster#1 | 1.23e-04 | 383 | 62 | 7 | Facebase_RNAseq_ratio_e10.5_MandibularArch_vs_MaxillaryArch_2500_K1 | |
| CoexpressionAtlas | FacebaseRNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_2500_k-means-cluster#3 | 1.87e-04 | 410 | 62 | 7 | Facebase_RNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_2500_K3 | |
| CoexpressionAtlas | FacebaseRNAseq_e9.5_Olfactory Placode_top-relative-expression-ranked_2500_k-means-cluster#3 | 2.14e-04 | 419 | 62 | 7 | Facebase_RNAseq_e9.5_Olfactory Placode_2500_K3 | |
| CoexpressionAtlas | FacebaseRNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_top-relative-expression-ranked_2500_k-means-cluster#1 | 2.17e-04 | 420 | 62 | 7 | Facebase_RNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_2500_K1 | |
| CoexpressionAtlas | FacebaseRNAseq_e8.5_Non-Floor Plate Neural Epithelium_top-relative-expression-ranked_1000_k-means-cluster#4 | 2.31e-04 | 298 | 62 | 6 | Facebase_RNAseq_e8.5_Non-Floor Plate Neural Epithelium_1000_K4 | |
| CoexpressionAtlas | FacebaseRNAseq_e10.5_Mandibular Arch_top-relative-expression-ranked_2500_k-means-cluster#1 | 2.61e-04 | 433 | 62 | 7 | Facebase_RNAseq_e10.5_Mandibular Arch_2500_K1 | |
| ToppCell | Brain_organoid-organoid_Kanton_Nature-Organoid-4M-Stem_cells-ectodermal/neuroectodermal-like_cells|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type. | 4.30e-06 | 173 | 62 | 5 | 7e4a2f5f92fbed16406bd097c0119278e4053245 | |
| ToppCell | Fetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor | 6.44e-06 | 188 | 62 | 5 | c4c3b21ab723b0e9beff9ec84f8d68485f771528 | |
| Drug | 4-aminopiperidine | 3.28e-06 | 11 | 63 | 3 | CID000424361 | |
| Drug | Moxisylyte hydrochoride [964-52-3]; Down 200; 12.6uM; PC3; HT_HG-U133A | 1.61e-05 | 194 | 63 | 6 | 1804_DN | |
| Drug | Pyridoxine hydrochloride [58-56-0]; Up 200; 19.4uM; PC3; HT_HG-U133A | 1.65e-05 | 195 | 63 | 6 | 5813_UP | |
| Drug | Mephentermine hemisulfate [1212-72-2]; Down 200; 9.4uM; MCF7; HT_HG-U133A | 1.75e-05 | 197 | 63 | 6 | 3425_DN | |
| Drug | Rifampicin [13292-46-1]; Up 200; 4.8uM; HL60; HT_HG-U133A | 1.80e-05 | 198 | 63 | 6 | 2487_UP | |
| Drug | Neostigmine bromide [114-80-7]; Down 200; 13.2uM; MCF7; HT_HG-U133A | 1.80e-05 | 198 | 63 | 6 | 5335_DN | |
| Drug | Epivincamine [6835-99-0]; Up 200; 11.2uM; MCF7; HT_HG-U133A | 1.91e-05 | 200 | 63 | 6 | 6838_UP | |
| Disease | familial hemiplegic migraine 1 (implicated_via_orthology) | 1.18e-05 | 3 | 59 | 2 | DOID:0111181 (implicated_via_orthology) | |
| Disease | exfoliation syndrome | 2.35e-05 | 4 | 59 | 2 | EFO_0004235 | |
| Disease | migraine (implicated_via_orthology) | 2.35e-05 | 4 | 59 | 2 | DOID:6364 (implicated_via_orthology) | |
| Disease | chronic granulomatous disease (implicated_via_orthology) | 3.92e-05 | 5 | 59 | 2 | DOID:3265 (implicated_via_orthology) | |
| Disease | Gilles de la Tourette syndrome (is_implicated_in) | 5.87e-05 | 6 | 59 | 2 | DOID:11119 (is_implicated_in) | |
| Disease | Exfoliation Syndrome | 5.87e-05 | 6 | 59 | 2 | C0206368 | |
| Disease | hereditary ataxia (implicated_via_orthology) | 8.20e-05 | 7 | 59 | 2 | DOID:0050951 (implicated_via_orthology) | |
| Disease | rheumatoid arthritis (implicated_via_orthology) | 2.56e-04 | 12 | 59 | 2 | DOID:7148 (implicated_via_orthology) | |
| Disease | phosphatidylcholine 34:2 measurement | 7.30e-04 | 20 | 59 | 2 | EFO_0010376 | |
| Disease | serum non-albumin protein measurement | 7.77e-04 | 361 | 59 | 5 | EFO_0004568 | |
| Disease | muscular dystrophy (implicated_via_orthology) | 8.05e-04 | 21 | 59 | 2 | DOID:9884 (implicated_via_orthology) | |
| Disease | response to interferon | 1.14e-03 | 25 | 59 | 2 | EFO_0007859 | |
| Disease | intellectual disability (is_implicated_in) | 1.65e-03 | 30 | 59 | 2 | DOID:1059 (is_implicated_in) | |
| Disease | progressive supranuclear palsy | 1.76e-03 | 31 | 59 | 2 | MONDO_0019037 | |
| Disease | joint hypermobility measurement | 1.99e-03 | 33 | 59 | 2 | EFO_0007905 |
| Peptide | Gene | Start | Entry |
|---|---|---|---|
| TRAPPRPSAPQQGRR | 16 | A8MWP4 | |
| TSTPRRGRRQLPQTP | 2276 | O00555 | |
| RGRRQLPQTPSTPRP | 2281 | O00555 | |
| RPPPQERGSGRRSPL | 61 | P59051 | |
| QRRPPARPGPLSTAN | 371 | O60512 | |
| GPSARQPLPRRNVPV | 866 | Q8TDY4 | |
| QKPQRPRRPASPIST | 21 | P07360 | |
| PAPRPARTPGTLQRQ | 631 | Q6UY14 | |
| RPPQPQASVPLRLTR | 1831 | Q6UVK1 | |
| TPPQPARRQSRRSPA | 626 | Q9Y3L3 | |
| RPRPPSRSRAAQSPG | 21 | O94989 | |
| RPPSSPTPGSRRRRQ | 11 | Q96AQ1 | |
| RPPSSPTPGSRRRRQ | 11 | Q96LY2 | |
| GRRQLPQTPLTPRPS | 2186 | Q00975 | |
| SLPRPSAGLPSRQRP | 486 | Q96KQ4 | |
| PRPVQRTQSVPVRRP | 811 | Q86YV0 | |
| QSPGRSPRLPRSPRL | 16 | Q8IUD2 | |
| IPPPQSTKPGRGRRT | 431 | P98082 | |
| TARRTPPGQQRPHPR | 131 | Q8IYF1 | |
| PPPSTLQGRRPRAQA | 336 | Q96DN6 | |
| SSSLRPSQRRPRRPP | 356 | Q96DN6 | |
| MSPPSPGRRREQRRP | 1 | Q03252 | |
| SPRRRQAPSLPLPGR | 91 | Q08397 | |
| GVNSRNPRRPPPSSV | 196 | Q86W50 | |
| PGTPITVRERRPSQP | 201 | Q6ZTU2 | |
| TPQRRPVSSIHPPGR | 766 | P50570 | |
| RARQPQSPPRTRESP | 3236 | O95613 | |
| LPPQTPPQTRRRRRA | 321 | P21917 | |
| PQRRGTPPLTPGRLT | 1066 | Q9Y3Q4 | |
| RRRQARPGPQSPGSP | 336 | A6NI72 | |
| RRRQARPGPQSPGSP | 311 | A8MVU1 | |
| PSRPGALPEQTRPLR | 81 | Q9H074 | |
| SPNTPEPAPRARRRG | 346 | O43182 | |
| PRRTLSAPPAQRRRP | 486 | O43900 | |
| PIEGRSPRSPRNNPV | 771 | P32927 | |
| QEIPTPRPRRLRSPS | 121 | Q9P2K1 | |
| GPSRRRQPPVSPLTL | 381 | Q6UUV7 | |
| SQPPRVREQRPRERP | 286 | Q9UN86 | |
| SLPPRRRAPPGRQRL | 31 | Q6P0Q8 | |
| RPQVLRPTSPRNISP | 66 | Q1W209 | |
| RQSPRGVTPPLSPIR | 66 | Q8N4W6 | |
| RPGPPFNITPRRARR | 1796 | O75923 | |
| SLPERTPGNERPPRR | 36 | P82673 | |
| RQQVSPPRSPQREPR | 56 | Q5VT97 | |
| GRRSPSPSRILPQPQ | 646 | O15034 | |
| RPLPERRSPNPQLLT | 66 | Q9BT56 | |
| RRRGERPSQPPQAVP | 31 | Q15464 | |
| SVSNPRGRPSRGRPP | 11 | Q8NFW8 | |
| PLPQPQSRSGSRRTR | 581 | A6NI28 | |
| PQRQTLSRPPTPRRG | 286 | Q9H4M7 | |
| RVSPRSAAPGPRPQQ | 161 | Q9NTG1 | |
| PPSRSPRVPRSRRQV | 66 | Q8IYJ0 | |
| PRPSILQPGPARLSR | 51 | Q5T036 | |
| QGPPPPRRESRTETR | 911 | P48634 | |
| RLPVPGPRRRNPRTT | 1126 | Q9UL54 | |
| QPRSPPRSERQPRPR | 126 | Q13875 | |
| PGIPRQLPTAPARRQ | 11 | E7EW31 | |
| RSPSPPRQTPNGAVR | 391 | E7EW31 | |
| TARPSQPPLPRRSTR | 881 | Q9ULV3 | |
| PRPQPRARSRSQPGL | 106 | Q70EK9 | |
| PPRGQLQPSRPTRAR | 166 | Q8IXZ2 | |
| ISSTPQPERRQPPQR | 506 | Q08AE8 | |
| TPAPRRPLQRRRPGT | 221 | Q9GZW5 | |
| PTPNPGSRRLRPSQS | 316 | Q9Y2B5 | |
| RGRQLRLQRPTPSTP | 331 | Q9H4Z2 | |
| QVPRPTALPRRQPTV | 2686 | P15822 | |
| PREPARQLRNPPTTI | 311 | Q15554 |