Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	ZNF813 CREBRF ZNF525 ATF6 CHD2 ATF1 ZNF600 ZNF761 ZFAT PPARA PPARD SCRT1 ADNP HNF4A CREB1 ZNF501 ZNF559 ZNF461	1.47e-11	1459	37	18	GO:0000977
GeneOntologyMolecularFunction	DNA-binding transcription factor activity, RNA polymerase II-specific	ZNF813 CREBRF ZNF525 ATF6 ATF1 ZNF600 ZNF761 ZFAT PPARA PPARD SCRT1 ADNP HNF4A CREB1 ZNF559 ZNF461	1.12e-09	1412	37	16	GO:0000981
GeneOntologyMolecularFunction	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ZNF813 ZNF525 ATF6 CHD2 ATF1 ZNF600 ZNF761 ZFAT PPARA PPARD SCRT1 HNF4A CREB1 ZNF501 ZNF461	1.94e-09	1244	37	15	GO:0000978
GeneOntologyMolecularFunction	cis-regulatory region sequence-specific DNA binding	ZNF813 ZNF525 ATF6 CHD2 ATF1 ZNF600 ZNF761 ZFAT PPARA PPARD SCRT1 HNF4A CREB1 ZNF501 ZNF461	2.60e-09	1271	37	15	GO:0000987
GeneOntologyMolecularFunction	DNA-binding transcription activator activity, RNA polymerase II-specific	CREBRF ATF6 ATF1 ZNF600 ZFAT PPARA HNF4A CREB1	6.86e-06	560	37	8	GO:0001228
GeneOntologyMolecularFunction	DNA-binding transcription activator activity	CREBRF ATF6 ATF1 ZNF600 ZFAT PPARA HNF4A CREB1	7.41e-06	566	37	8	GO:0001216
GeneOntologyMolecularFunction	transcription coregulator binding	PPARA PPARD HNF4A CREB1	1.28e-04	140	37	4	GO:0001221
GeneOntologyMolecularFunction	transcription coactivator binding	PPARA PPARD CREB1	1.36e-04	54	37	3	GO:0001223
GeneOntologyMolecularFunction	nuclear receptor activity	PPARA PPARD HNF4A	1.86e-04	60	37	3	GO:0004879
GeneOntologyMolecularFunction	ligand-activated transcription factor activity	PPARA PPARD HNF4A	1.96e-04	61	37	3	GO:0098531
GeneOntologyMolecularFunction	nuclear steroid receptor activity	PPARA PPARD	9.76e-04	25	37	2	GO:0003707
GeneOntologyMolecularFunction	long-chain fatty acid binding	PPARD HNF4A	1.23e-03	28	37	2	GO:0036041
GeneOntologyMolecularFunction	transition metal ion binding	UBA5 TRAF5 PPARA PPARD KMT2B ADNP HNF4A JMJD6	1.27e-03	1189	37	8	GO:0046914
GeneOntologyBiologicalProcess	positive regulation of fatty acid metabolic process	PPARA PPARD HNF4A	1.04e-04	51	37	3	GO:0045923
GeneOntologyBiologicalProcess	positive regulation of transcription by RNA polymerase II	CREBRF ATF6 ATF1 ZNF600 ZFAT PPARA PPARD HNF4A CREB1 JMJD6	1.21e-04	1390	37	10	GO:0045944
GeneOntologyBiologicalProcess	inhibition of non-skeletal tissue mineralization	ATF1 CREB1	1.40e-04	10	37	2	GO:0140928
GeneOntologyBiologicalProcess	steroid hormone receptor signaling pathway	CREBRF UBA5 PPARA PPARD	1.67e-04	155	37	4	GO:0043401
GeneOntologyBiologicalProcess	negative regulation of cholesterol storage	PPARA PPARD	2.04e-04	12	37	2	GO:0010887
GeneOntologyBiologicalProcess	positive regulation of lipid metabolic process	PPARA PPARD HNF4A CREB1	2.12e-04	165	37	4	GO:0045834
GeneOntologyCellularComponent	ATF4-CREB1 transcription factor complex	ATF1 CREB1	1.82e-05	4	37	2	GO:1990589
GeneOntologyCellularComponent	chromatin	ATF6 ATP1B4 CHD2 ATF1 PPARA PPARD ADNP HNF4A CREB1	8.85e-04	1480	37	9	GO:0000785
GeneOntologyCellularComponent	RNA polymerase II transcription regulator complex	ATF6 ATF1 ADNP CREB1	1.32e-03	272	37	4	GO:0090575
MousePheno	abnormal fatty acids level	SCUBE3 PPARA PPARD KMT2B HNF4A	7.20e-05	289	22	5	MP:0005280
MousePheno	abnormal fetal growth/weight/body size	CHD2 PPARD CREB1 JMJD6 GLG1	1.03e-04	312	22	5	MP:0004197
MousePheno	abnormal circulating triglyceride level	SCUBE3 PPARA PPARD KMT2B HNF4A GLG1	1.11e-04	516	22	6	MP:0011969
MousePheno	increased lipid level	CHD2 PPARA PPARD KMT2B HNF4A GLG1 USP47	2.23e-04	847	22	7	MP:0014460
MousePheno	abnormal prenatal growth/weight/body size	TASP1 CHD2 ZFAT PPARD KMT2B HNF4A CREB1 JMJD6 GLG1	2.40e-04	1493	22	9	MP:0004196
MousePheno	abnormal triglyceride level	SCUBE3 PPARA PPARD KMT2B HNF4A GLG1	3.55e-04	639	22	6	MP:0000187
MousePheno	decreased fetal size	CHD2 PPARD CREB1 GLG1	4.07e-04	229	22	4	MP:0004200
MousePheno	hepatic steatosis	ATF6 PPARA KMT2B HNF4A	4.27e-04	232	22	4	MP:0002628
MousePheno	abnormal free fatty acids level	SCUBE3 PPARA KMT2B HNF4A	4.34e-04	233	22	4	MP:0010358
MousePheno	abnormal fetal size	CHD2 PPARD CREB1 GLG1	4.63e-04	237	22	4	MP:0004198
Domain	zf-C2H2	ZNF813 ZNF525 ZNF600 ZNF761 ZFAT SCRT1 ADNP ZNF501 ZNF559 ZNF461	6.51e-07	693	37	10	PF00096
Domain	ZINC_FINGER_C2H2_2	ZNF813 ZNF525 ZNF600 ZNF761 ZFAT SCRT1 ADNP ZNF501 ZNF559 ZNF461	1.80e-06	775	37	10	PS50157
Domain	ZINC_FINGER_C2H2_1	ZNF813 ZNF525 ZNF600 ZNF761 ZFAT SCRT1 ADNP ZNF501 ZNF559 ZNF461	1.84e-06	777	37	10	PS00028
Domain	Znf_C2H2	ZNF813 ZNF525 ZNF600 ZNF761 ZFAT SCRT1 ADNP ZNF501 ZNF559 ZNF461	2.53e-06	805	37	10	IPR007087
Domain	ZnF_C2H2	ZNF813 ZNF525 ZNF600 ZNF761 ZFAT SCRT1 ADNP ZNF501 ZNF559 ZNF461	2.61e-06	808	37	10	SM00355
Domain	BZIP_BASIC	CREBRF ATF6 ATF1 CREB1	3.56e-06	53	37	4	PS00036
Domain	bZIP	CREBRF ATF6 ATF1 CREB1	3.84e-06	54	37	4	IPR004827
Domain	Znf_C2H2/integrase_DNA-bd	ZNF813 ZNF600 ZNF761 ZFAT SCRT1 ADNP ZNF501 ZNF559 ZNF461	6.26e-06	694	37	9	IPR013087
Domain	1Cnucl_rcpt	PPARA PPARD	1.14e-05	3	37	2	IPR003074
Domain	KID	ATF1 CREB1	1.14e-05	3	37	2	PS50953
Domain	Coactivator_CBP_pKID	ATF1 CREB1	1.14e-05	3	37	2	IPR003102
Domain	pKID	ATF1 CREB1	1.14e-05	3	37	2	PF02173
Domain	Znf_C2H2-like	ZNF813 ZNF600 ZNF761 ZFAT SCRT1 ADNP ZNF501 ZNF559 ZNF461	1.88e-05	796	37	9	IPR015880
Domain	Leuzip_CREB	ATF1 CREB1	2.29e-05	4	37	2	IPR001630
Domain	zf-C2H2_6	ZNF813 ZNF600 ZNF761 SCRT1 ZNF501 ZNF461	3.23e-05	314	37	6	PF13912
Domain	bZIP_1	ATF6 ATF1 CREB1	4.11e-05	34	37	3	PF00170
Domain	-	ZNF813 ZNF600 ZNF761 ZFAT SCRT1 ZNF501 ZNF559 ZNF461	4.44e-05	679	37	8	3.30.160.60
Domain	zf-C4	PPARA PPARD HNF4A	1.02e-04	46	37	3	PF00105
Domain	NUCLEAR_REC_DBD_1	PPARA PPARD HNF4A	1.02e-04	46	37	3	PS00031
Domain	Znf_hrmn_rcpt	PPARA PPARD HNF4A	1.02e-04	46	37	3	IPR001628
Domain	Nuclear_hrmn_rcpt	PPARA PPARD HNF4A	1.02e-04	46	37	3	IPR001723
Domain	ZnF_C4	PPARA PPARD HNF4A	1.02e-04	46	37	3	SM00399
Domain	NUCLEAR_REC_DBD_2	PPARA PPARD HNF4A	1.02e-04	46	37	3	PS51030
Domain	-	PPARA PPARD HNF4A	1.09e-04	47	37	3	1.10.565.10
Domain	HOLI	PPARA PPARD HNF4A	1.16e-04	48	37	3	SM00430
Domain	Nucl_hrmn_rcpt_lig-bd	PPARA PPARD HNF4A	1.16e-04	48	37	3	IPR000536
Domain	Hormone_recep	PPARA PPARD HNF4A	1.16e-04	48	37	3	PF00104
Domain	BRLZ	ATF6 ATF1 CREB1	1.48e-04	52	37	3	SM00338
Domain	BZIP	ATF6 ATF1 CREB1	1.57e-04	53	37	3	PS50217
Domain	-	PPARA PPARD HNF4A	1.95e-04	57	37	3	3.30.50.10
Domain	Znf_NHR/GATA	PPARA PPARD HNF4A	2.05e-04	58	37	3	IPR013088
Domain	cEGF	SCUBE3 MATN2	1.20e-03	26	37	2	IPR026823
Domain	cEGF	SCUBE3 MATN2	1.20e-03	26	37	2	PF12662
Domain	TF_DNA-bd	ATF1 CREB1	2.43e-03	37	37	2	IPR008917
Domain	KRAB	ZNF813 ZNF761 ZNF559 ZNF461	5.32e-03	358	37	4	PS50805
Domain	KRAB	ZNF813 ZNF761 ZNF559 ZNF461	5.32e-03	358	37	4	PF01352
Domain	KRAB	ZNF813 ZNF761 ZNF559 ZNF461	5.92e-03	369	37	4	SM00349
Domain	KRAB	ZNF813 ZNF761 ZNF559 ZNF461	5.98e-03	370	37	4	IPR001909
Domain	EGF_CA	SCUBE3 MATN2	1.26e-02	86	37	2	PF07645
Pathway	PID_P38_ALPHA_BETA_DOWNSTREAM_PATHWAY	ATF6 ATF1 CREB1	5.05e-05	38	27	3	M229
Pathway	WP_NUCLEAR_RECEPTORS	PPARA PPARD HNF4A	5.05e-05	38	27	3	M39657
Pathway	WP_NUCLEAR_RECEPTORS	PPARA PPARD HNF4A	5.05e-05	38	27	3	MM15865
Pathway	REACTOME_CREB_PHOSPHORYLATION	ATF1 CREB1	7.38e-05	7	27	2	M27096
Pathway	REACTOME_CREB_PHOSPHORYLATION	ATF1 CREB1	7.38e-05	7	27	2	MM14784
Pathway	WP_EFFECT_OF_INTESTINAL_MICROBIOME_ON_ANTICOAGULANT_RESPONSE_OF_VITAMIN_K_ANTAGONISTS	PPARA PPARD	9.82e-05	8	27	2	M45529
Pathway	WP_ENERGY_METABOLISM	PPARA PPARD CREB1	1.02e-04	48	27	3	M39590
Pathway	REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY	PPARA PPARD HNF4A	1.02e-04	48	27	3	MM14987
Pathway	REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY	PPARA PPARD HNF4A	1.38e-04	53	27	3	M8276
Pathway	REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION	ATP1B4 ZNF600 ZNF761 PPARA PPARD KMT2B HNF4A CREB1 ZNF559 ZNF461	1.45e-04	1387	27	10	M734
Pathway	REACTOME_UNFOLDED_PROTEIN_RESPONSE_UPR	CREBRF ATF6	2.30e-04	12	27	2	MM14981
Pathway	WP_SEROTONIN_RECEPTOR_467_AND_NR3C_SIGNALING	ATF1 CREB1	5.92e-04	19	27	2	M39358
Pathway	KEGG_MEDICUS_REFERENCE_TNF_P38_SIGNALING_PATHWAY	TRAF5 CREB1	9.50e-04	24	27	2	M47568
Pathway	PID_RXR_VDR_PATHWAY	PPARA PPARD	1.12e-03	26	27	2	M162
Pathway	REACTOME_NUCLEAR_EVENTS_KINASE_AND_TRANSCRIPTION_FACTOR_ACTIVATION	ATF1 CREB1	1.20e-03	27	27	2	MM14779
Pathway	REACTOME_MAPK_TARGETS_NUCLEAR_EVENTS_MEDIATED_BY_MAP_KINASES	ATF1 CREB1	1.29e-03	28	27	2	MM15132
Pathway	WP_DRAVET_SYNDROME	CHD2 PCDH19	1.29e-03	28	27	2	M45519
Pathway	WP_EICOSANOID_METABOLISM_VIA_LIPOOXYGENASES_LOX	PPARA PPARD	1.39e-03	29	27	2	M39858
Pathway	WP_NUCLEAR_RECEPTORS_IN_LIPID_METABOLISM_AND_TOXICITY	PPARA PPARD	1.49e-03	30	27	2	MM15866
Pathway	REACTOME_MAPK_TARGETS_NUCLEAR_EVENTS_MEDIATED_BY_MAP_KINASES	ATF1 CREB1	1.59e-03	31	27	2	M15195
Pathway	WP_PRION_DISEASE_PATHWAY	CHD2 CREB1	1.69e-03	32	27	2	M39636
Pathway	BIOCARTA_NUCLEARRS_PATHWAY	PPARA PPARD	1.80e-03	33	27	2	MM1448
Pathway	BIOCARTA_NUCLEARRS_PATHWAY	PPARA PPARD	1.91e-03	34	27	2	M16393
Pathway	WP_ADIPOGENESIS	PPARA PPARD CREB1	1.95e-03	131	27	3	M39505
Pathway	WP_NUCLEAR_RECEPTORS_IN_LIPID_METABOLISM_AND_TOXICITY	PPARA PPARD	2.02e-03	35	27	2	M39488
Pathway	WP_ADIPOGENESIS_GENES	PPARA PPARD CREB1	2.21e-03	137	27	3	MM15970
Pathway	REACTOME_FORMATION_OF_WDR5_CONTAINING_HISTONE_MODIFYING_COMPLEXES	TASP1 KMT2B	2.38e-03	38	27	2	MM17073
Pathway	REACTOME_NGF_STIMULATED_TRANSCRIPTION	ATF1 CREB1	2.51e-03	39	27	2	M29793
Pathway	REACTOME_FORMATION_OF_WDR5_CONTAINING_HISTONE_MODIFYING_COMPLEXES	TASP1 KMT2B	2.90e-03	42	27	2	M48018
Pathway	WP_IL11_SIGNALING	ATF1 CREB1	3.18e-03	44	27	2	M39716
Pathway	WP_RENINANGIOTENSINALDOSTERONE_SYSTEM_RAAS	ATF1 CREB1	3.18e-03	44	27	2	M39845
Pathway	PID_HNF3B_PATHWAY	HNF4A CREB1	3.32e-03	45	27	2	M106
Pathway	REACTOME_KIDNEY_DEVELOPMENT	HNF4A PCDH19	3.47e-03	46	27	2	M48243
Pubmed	Adipocyte arrestin domain-containing 3 protein (Arrdc3) regulates uncoupling protein 1 (Ucp1) expression in white adipose independently of canonical changes in β-adrenergic receptor signaling.	PPARA PPARD CREB1	7.46e-07	17	37	3	28291835
Pubmed	MRI monitoring of focal cerebral ischemia in peroxisome proliferator-activated receptor (PPAR)-deficient mice.	PPARA PPARD	1.10e-06	2	37	2	17451173
Pubmed	Neurogenic transdifferentiation of human adipose-derived stem cells? A critical protocol reevaluation with special emphasis on cell proliferation and cell cycle alterations.	ATF1 CREB1	1.10e-06	2	37	2	20945072
Pubmed	Expression of peroxisome proliferator-activated receptors (PPARs) in human urinary bladder carcinoma and growth inhibition by its agonists.	PPARA PPARD	1.10e-06	2	37	2	12594814
Pubmed	CREB function is required for normal thymic cellularity and post-irradiation recovery.	ATF1 CREB1	1.10e-06	2	37	2	15214044
Pubmed	PPARα/δ dual agonist H11 alleviates diabetic kidney injury by improving the metabolic disorders of tubular epithelial cells.	PPARA PPARD	1.10e-06	2	37	2	38387308
Pubmed	Reversible inhibition of CREB/ATF transcription factors in region CA1 of the dorsal hippocampus disrupts hippocampus-dependent spatial memory.	ATF1 CREB1	1.10e-06	2	37	2	11988175
Pubmed	ATF6α downregulation of PPARα promotes lipotoxicity-induced tubulointerstitial fibrosis.	ATF6 PPARA	1.10e-06	2	37	2	30639234
Pubmed	Dysregulation of hepatic zinc transporters in a mouse model of alcoholic liver disease.	PPARA HNF4A	1.10e-06	2	37	2	24924749
Pubmed	Lipolytic products activate peroxisome proliferator-activated receptor (PPAR) α and δ in brown adipocytes to match fatty acid oxidation with supply.	PPARA PPARD	1.10e-06	2	37	2	22685301
Pubmed	Association of peroxisome proliferator-activated receptor delta +294T/C with body mass index and interaction with peroxisome proliferator-activated receptor alpha L162V.	PPARA PPARD	1.10e-06	2	37	2	16652134
Pubmed	PPAR alpha, more than PPAR delta, mediates the hepatic and skeletal muscle alterations induced by the PPAR agonist GW0742.	PPARA PPARD	1.10e-06	2	37	2	18593727
Pubmed	Double gene deletion reveals the lack of cooperation between PPARalpha and PPARbeta in skeletal muscle.	PPARA PPARD	1.10e-06	2	37	2	17466944
Pubmed	Hepatocyte nuclear factor 4alpha coordinates a transcription factor network regulating hepatic fatty acid metabolism.	PPARA HNF4A	1.10e-06	2	37	2	19933841
Pubmed	Unlike PPARgamma, PPARalpha or PPARbeta/delta activation does not promote human monocyte differentiation toward alternative macrophages.	PPARA PPARD	1.10e-06	2	37	2	19527689
Pubmed	Bezafibrate is a dual ligand for PPARalpha and PPARbeta: studies using null mice.	PPARA PPARD	1.10e-06	2	37	2	12782154
Pubmed	Peroxisome proliferator activated receptor delta genotype in relation to cardiovascular risk factors and risk of coronary heart disease in hypercholesterolaemic men.	PPARA PPARD	1.10e-06	2	37	2	14641801
Pubmed	The pharmacodynamic and differential gene expression analysis of PPAR α/δ agonist GFT505 in CDAHFD-induced NASH model.	PPARA PPARD	1.10e-06	2	37	2	33326461
Pubmed	Depletion of cAMP-response element-binding protein/ATF1 inhibits adipogenic conversion of 3T3-L1 cells ectopically expressing CCAAT/enhancer-binding protein (C/EBP) alpha, C/EBP beta, or PPAR gamma 2.	ATF1 CREB1	1.10e-06	2	37	2	17071615
Pubmed	Aspirin binds to PPARα to stimulate hippocampal plasticity and protect memory.	PPARA PPARD	1.10e-06	2	37	2	30012602
Pubmed	Role of PPARα and HNF4α in stress-mediated alterations in lipid homeostasis.	PPARA HNF4A	1.10e-06	2	37	2	23967086
Pubmed	Muscle-building supplement β-hydroxy β-methylbutyrate binds to PPARα to improve hippocampal functions in mice.	PPARA PPARD	1.10e-06	2	37	2	37437568
Pubmed	Oleylethanolamide regulates feeding and body weight through activation of the nuclear receptor PPAR-alpha.	PPARA PPARD	1.10e-06	2	37	2	12955147
Pubmed	Fatty acid homeostasis and induction of lipid regulatory genes in skeletal muscles of peroxisome proliferator-activated receptor (PPAR) alpha knock-out mice. Evidence for compensatory regulation by PPAR delta.	PPARA PPARD	1.10e-06	2	37	2	12118038
Pubmed	Peroxisome proliferator-activated receptor (PPAR)-beta/delta stimulates differentiation and lipid accumulation in keratinocytes.	PPARA PPARD	1.10e-06	2	37	2	15102088
Pubmed	Transcriptional profiling reveals divergent roles of PPARalpha and PPARbeta/delta in regulation of gene expression in mouse liver.	PPARA PPARD	1.10e-06	2	37	2	20009009
Pubmed	A candidate gene study reveals association between a variant of the Peroxisome Proliferator-Activated Receptor Gamma (PPAR-γ) gene and systemic sclerosis.	PPARA PPARD	1.10e-06	2	37	2	25986483
Pubmed	The peroxisome proliferator-activated receptor delta +294T/C polymorphism in relation to lipoprotein metabolism in patients with diabetes mellitus type 2 and in non-diabetic controls.	PPARA PPARD	1.10e-06	2	37	2	16285997
Pubmed	Activation of Peroxisome Proliferator-Activated Receptors α and δ Synergizes with Inflammatory Signals to Enhance Adoptive Cell Therapy.	PPARA PPARD	1.10e-06	2	37	2	30573521
Pubmed	Aspirin Induces Lysosomal Biogenesis and Attenuates Amyloid Plaque Pathology in a Mouse Model of Alzheimer's Disease via PPARα.	PPARA PPARD	1.10e-06	2	37	2	29967008
Pubmed	Shear stress induces synthetic-to-contractile phenotypic modulation in smooth muscle cells via peroxisome proliferator-activated receptor alpha/delta activations by prostacyclin released by sheared endothelial cells.	PPARA PPARD	1.10e-06	2	37	2	19628794
Pubmed	Induction of cardiac Angptl4 by dietary fatty acids is mediated by peroxisome proliferator-activated receptor beta/delta and protects against fatty acid-induced oxidative stress.	PPARA PPARD	3.30e-06	3	37	2	20378851
Pubmed	Association between peroxisome proliferator-activated receptor-alpha, delta, and gamma polymorphisms and risk of coronary heart disease: A case-control study and meta-analysis.	PPARA PPARD	3.30e-06	3	37	2	27512842
Pubmed	Fatty acids and eicosanoids regulate gene expression through direct interactions with peroxisome proliferator-activated receptors alpha and gamma.	PPARA PPARD	3.30e-06	3	37	2	9113987
Pubmed	Peroxisome Proliferator Activated Receptor Gamma Controls Mature Brown Adipocyte Inducibility through Glycerol Kinase.	PPARA PPARD	3.30e-06	3	37	2	29346772
Pubmed	Detection and characterization of EWSR1/ATF1 and EWSR1/CREB1 chimeric transcripts in clear cell sarcoma (melanoma of soft parts).	ATF1 CREB1	3.30e-06	3	37	2	19561568
Pubmed	Changes in plasma PPARs levels in migraine patients.	PPARA PPARD	3.30e-06	3	37	2	25758678
Pubmed	Vasoactive intestinal peptide upregulates MUC2 intestinal mucin via CREB/ATF1.	ATF1 CREB1	3.30e-06	3	37	2	16227528
Pubmed	Modulating Intrafollicular Hormonal Milieu in Controlled Ovarian Stimulation: Insights From PPAR Expression in Human Granulosa Cells.	PPARA PPARD	3.30e-06	3	37	2	26332656
Pubmed	Tumors with EWSR1-CREB1 and EWSR1-ATF1 fusions: the current status.	ATF1 CREB1	3.30e-06	3	37	2	22510762
Pubmed	Dynamic repression by BCL6 controls the genome-wide liver response to fasting and steatosis.	PPARA PPARD	3.30e-06	3	37	2	30983568
Pubmed	Role of tissue-specific transcription factor LFB3 in a cyclic AMP-responsive enhancer of the urokinase-type plasminogen activator gene in LLC-PK1 cells.	ATF1 CREB1	3.30e-06	3	37	2	9671480
Pubmed	Elafibranor Inhibits Chronic Kidney Disease Progression in NASH Mice.	PPARA PPARD	3.30e-06	3	37	2	31321239
Pubmed	Upregulation of BDNF and hippocampal functions by a hippocampal ligand of PPARα.	PPARA PPARD	3.30e-06	3	37	2	32315292
Pubmed	Inhibition of adult liver progenitor (oval) cell growth and viability by an agonist of the peroxisome proliferator activated receptor (PPAR) family member gamma, but not alpha or delta.	PPARA PPARD	3.30e-06	3	37	2	15917308
Pubmed	Association and interaction of PPARα, δ, and γ gene polymorphisms with low-density lipoprotein-cholesterol in a Chinese Han population.	PPARA PPARD	3.30e-06	3	37	2	26098621
Pubmed	Roles of PPARs on regulating myocardial energy and lipid homeostasis.	PPARA PPARD	3.30e-06	3	37	2	17356846
Pubmed	Keratin 79 is a PPARA target that is highly expressed by liver damage.	PPARA HNF4A	3.30e-06	3	37	2	36796223
Pubmed	Roles of PPAR transcription factors in the energetic metabolic switch occurring during adult neurogenesis.	PPARA PPARD	3.30e-06	3	37	2	27860527
Pubmed	Peroxisome proliferator-activated receptor beta/delta (PPARbeta/delta) but not PPARalpha serves as a plasma free fatty acid sensor in liver.	PPARA PPARD	3.30e-06	3	37	2	19805517
Pubmed	Protective roles of adiponectin and molecular signatures of HNF4α and PPARα as downstream targets of adiponectin in pancreatic β cells.	PPARA HNF4A	3.30e-06	3	37	2	37806486
Pubmed	Gene-gene interactions among PPARα/δ/γ polymorphisms for hypertriglyceridemia in Chinese Han population.	PPARA PPARD	3.30e-06	3	37	2	23262340
Pubmed	Gemfibrozil and fenofibrate, Food and Drug Administration-approved lipid-lowering drugs, up-regulate tripeptidyl-peptidase 1 in brain cells via peroxisome proliferator-activated receptor α: implications for late infantile Batten disease therapy.	PPARA PPARD	3.30e-06	3	37	2	22989886
Pubmed	Association of polymorphisms of peroxisome proliferator activated receptors in early and late onset of type 2 diabetes mellitus.	PPARA PPARD	3.30e-06	3	37	2	28292576
Pubmed	The acyl-CoA thioesterase I is regulated by PPARalpha and HNF4alpha via a distal response element in the promoter.	PPARA HNF4A	3.30e-06	3	37	2	17485727
Pubmed	Mouse carnitine-acylcarnitine translocase (CACT) is transcriptionally regulated by PPARalpha and PPARdelta in liver cells.	PPARA PPARD	3.30e-06	3	37	2	19577614
Pubmed	Peroxisome proliferator-activated receptors in squamous cell carcinoma and its precursors.	PPARA PPARD	3.30e-06	3	37	2	15811118
Pubmed	Fatty acids regulate perilipin5 in muscle by activating PPARδ.	PPARA PPARD	3.30e-06	3	37	2	23606724
Pubmed	[Effects of PPARD-87T > C and interactions with single nucleotide polymorphisms in PPARA and PPARG on abdominal obesity].	PPARA PPARD	3.30e-06	3	37	2	22944052
Pubmed	Effects of PPARalpha, gamma and delta haplotypes on plasma levels of lipids, severity and progression of coronary atherosclerosis and response to statin therapy in the lipoprotein coronary atherosclerosis study.	PPARA PPARD	3.30e-06	3	37	2	15128052
Pubmed	Treadmill workout activates PPARα in the hippocampus to upregulate ADAM10, decrease plaques and improve cognitive functions in 5XFAD mouse model of Alzheimer's disease.	PPARA PPARD	3.30e-06	3	37	2	36682514
Pubmed	CD36 is essential for endurance improvement, changes in whole-body metabolism, and efficient PPAR-related transcriptional responses in the muscle with exercise training.	PPARA PPARD	3.30e-06	3	37	2	28526781
Pubmed	cAMP-independent activation of the adenovirus type 12 E2 promoter correlates with the recruitment of CREB-1/ATF-1, E1A(12S), and CBP to the E2-CRE.	ATF1 CREB1	3.30e-06	3	37	2	10722738
Pubmed	PPARα/RXRα downregulates amino acid catabolism in the liver via interaction with HNF4α promoting its proteasomal degradation.	PPARA HNF4A	3.30e-06	3	37	2	33422545
Pubmed	PPAR activation as a regulator of lipid metabolism, nitric oxide production and lipid peroxidation in the placenta from type 2 diabetic patients.	PPARA PPARD	3.30e-06	3	37	2	23811234
Pubmed	Activating transcription factor-1 can mediate Ca(2+)- and cAMP-inducible transcriptional activation.	ATF1 CREB1	3.30e-06	3	37	2	8384217
Pubmed	Effects of PPARs/20-HETE on the renal impairment under diabetic conditions.	PPARA PPARD	3.30e-06	3	37	2	31163124
Pubmed	Identification of two mPPAR related receptors and evidence for the existence of five subfamily members.	PPARA PPARD	3.30e-06	3	37	2	8240342
Pubmed	PPAR alpha and PPAR delta transactivity and p300 binding activity induced by arachidonic acid in colorectal cancer cell line Caco-2.	PPARA PPARD	3.30e-06	3	37	2	18797151
Pubmed	Effects of peroxisome proliferator-activated receptors, dietary fat intakes and gene-diet interactions on peak particle diameters of low-density lipoproteins.	PPARA PPARD	3.30e-06	3	37	2	21487230
Pubmed	Transcriptional regulation of the MHC class II trans-activator (CIITA) promoter III: identification of a novel regulatory region in the 5'-untranslated region and an important role for cAMP-responsive element binding protein 1 and activating transcription factor-1 in CIITA-promoter III transcriptional activation in B lymphocytes.	ATF1 CREB1	3.30e-06	3	37	2	12391222
Pubmed	Dehydroepiandrosterone sulfate mediates activation of transcription factors CREB and ATF-1 via a Gα11-coupled receptor in the spermatogenic cell line GC-2.	ATF1 CREB1	3.30e-06	3	37	2	23988737
Pubmed	Genetic manipulations of PPARs: effects on obesity and metabolic disease.	PPARA PPARD	3.30e-06	3	37	2	17389768
Pubmed	Differential inhibition of macrophage foam-cell formation and atherosclerosis in mice by PPARalpha, beta/delta, and gamma.	PPARA PPARD	3.30e-06	3	37	2	15578089
Pubmed	PPAR and GST polymorphisms may predict changes in intellectual functioning in medulloblastoma survivors.	PPARA PPARD	3.30e-06	3	37	2	30607709
Pubmed	PPAR nuclear receptors and altered RPE lipid metabolism in age-related macular degeneration.	PPARA PPARD	3.30e-06	3	37	2	20238044
Pubmed	Peroxisome proliferator-activated receptors, orphans with ligands and functions.	PPARA PPARD	3.30e-06	3	37	2	9211064
Pubmed	Selective intranuclear redistribution of PPAR isoforms by RXR alpha.	PPARA PPARD	3.30e-06	3	37	2	11923467
Pubmed	Screening of Peroxisome Proliferator-Activated Receptors (PPARs) α, γ and α Gene Polymorphisms for Obesity and Metabolic Syndrome Association in the Multi-Ethnic Malaysian Population.	PPARA PPARD	3.30e-06	3	37	2	26673968
Pubmed	Phospholipase A2-modified low-density lipoprotein activates macrophage peroxisome proliferator-activated receptors.	PPARA PPARD	3.30e-06	3	37	2	19948841
Pubmed	MSK1 is required for CREB phosphorylation in response to mitogens in mouse embryonic stem cells.	ATF1 CREB1	3.30e-06	3	37	2	11018520
Pubmed	BRCA1 physically and functionally interacts with ATF1.	ATF1 CREB1	3.30e-06	3	37	2	10945975
Pubmed	Expression of the peroxisome proliferator-activated receptors-alpha, -beta, and -gamma in ovarian carcinoma effusions is associated with poor chemoresponse and shorter survival.	PPARA PPARD	3.30e-06	3	37	2	19157507
Pubmed	Expression of peroxisome proliferator activated receptor mRNA in normal and tumorigenic rodent mammary glands.	PPARA PPARD	3.30e-06	3	37	2	9918810
Pubmed	Differential expression and activation of a family of murine peroxisome proliferator-activated receptors.	PPARA PPARD	3.30e-06	3	37	2	8041794
Pubmed	Cyp1b1 affects external control of mouse hepatocytes, fatty acid homeostasis and signaling involving HNF4α and PPARα.	PPARA HNF4A	3.30e-06	3	37	2	27036855
Pubmed	Prostaglandin F(2alpha) stimulates MEK-ERK signalling but decreases the expression of alkaline phosphatase in dental pulp cells.	ATF1 CREB1	3.30e-06	3	37	2	20536573
Pubmed	Peroxisome proliferator-activated receptors are altered in pathologies of the human placenta: gestational diabetes mellitus, intrauterine growth restriction and preeclampsia.	PPARA PPARD	3.30e-06	3	37	2	20045185
Pubmed	Single gene contributions: genetic variants of peroxisome proliferator-activated receptor (isoforms alpha, beta/delta and gamma) and mechanisms of dyslipidemias.	PPARA PPARD	3.30e-06	3	37	2	18388689
Pubmed	A census of human transcription factors: function, expression and evolution.	CREBRF ATF6 ATF1 PPARA PPARD ADNP HNF4A CREB1	4.13e-06	908	37	8	19274049
Pubmed	Identification of bZIP interaction partners of viral proteins HBZ, MEQ, BZLF1, and K-bZIP using coiled-coil arrays.	ATF6 ATF1 CREB1	5.92e-06	33	37	3	20102225
Pubmed	[Association of regulatory genes polymorphisms with aerobic and anaerobic performance of athletes].	PPARA PPARD	6.60e-06	4	37	2	17926914
Pubmed	Heme oxygenase-1 regulates dendritic cell function through modulation of p38 MAPK-CREB/ATF1 signaling.	ATF1 CREB1	6.60e-06	4	37	2	24719331
Pubmed	The cAMP-regulated enhancer-binding protein ATF-1 activates transcription in response to cAMP-dependent protein kinase A.	ATF1 CREB1	6.60e-06	4	37	2	1655749
Pubmed	Activation of peroxisome proliferator-activated receptor α stimulates ADAM10-mediated proteolysis of APP.	PPARA PPARD	6.60e-06	4	37	2	26080426
Pubmed	Induction of Grp78/BiP by translational block: activation of the Grp78 promoter by ATF4 through and upstream ATF/CRE site independent of the endoplasmic reticulum stress elements.	ATF1 CREB1	6.60e-06	4	37	2	12871976
Pubmed	Glycogen synthase 2 is a novel target gene of peroxisome proliferator-activated receptors.	PPARD HNF4A	6.60e-06	4	37	2	17437057
Pubmed	Secalonic acid D alters the expression and phosphorylation of the transcription factors and their binding to cAMP response element in developing murine secondary palate.	ATF1 CREB1	6.60e-06	4	37	2	11354513
Pubmed	Nuclear receptors PPARbeta/delta and PPARalpha direct distinct metabolic regulatory programs in the mouse heart.	PPARA PPARD	6.60e-06	4	37	2	18037994
Pubmed	Cloning and identification of rat deoxyuridine triphosphatase as an inhibitor of peroxisome proliferator-activated receptor alpha.	PPARA PPARD	6.60e-06	4	37	2	8910358
Interaction	RBPJ interactions	ATF1 KMT2B ADNP HNF4A JMJD6 USP47	6.33e-06	254	37	6	int:RBPJ
Interaction	SREBF2 interactions	ATF6 TRAF5 ZFAT HNF4A CREB1 JMJD6	1.54e-05	297	37	6	int:SREBF2
Cytoband	19q13.42	ZNF813 ZNF525 ZNF761	1.43e-04	125	37	3	19q13.42
Cytoband	Ensembl 112 genes in cytogenetic band chr19q13	ZNF813 ZNF525 ZNF600 ZNF761 KMT2B ZNF461	3.53e-04	1192	37	6	chr19q13
Cytoband	20q13.12	WFDC11 HNF4A	1.09e-03	60	37	2	20q13.12
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF813 ZNF525 ZNF600 ZNF761 ZFAT SCRT1 ZNF501 ZNF559 ZNF461	3.98e-07	718	26	9	28
GeneFamily	Nuclear hormone receptors	PPARA PPARD HNF4A	4.66e-05	49	26	3	71
GeneFamily	Basic leucine zipper proteins	ATF6 ATF1 CREB1	4.66e-05	49	26	3	506
Drug	NSC46155	PPARA PPARD MUSK	8.60e-07	12	37	3	CID000457869
Drug	indeglitazar	PPARA PPARD	7.70e-06	3	37	2	CID011395145
Drug	3-{5-methoxy-1-[(4-methoxyphenyl)sulfonyl]-1H-indol-3-yl}propanoic acid	PPARA PPARD	7.70e-06	3	37	2	DB07724
Drug	Bezafibrate	PPARA PPARD	7.70e-06	3	37	2	DB01393
Drug	2-methyl-c-5-(4-(5-methyl-2-(4-methylphenyl)-4-oxazolyl)butyl)-1,3-dioxane-r-2-carboxylic acid	PPARA PPARD	7.70e-06	3	37	2	ctd:C487401
Drug	AMPK inhibitor	ATF1 PPARA PPARD CREB1	1.31e-05	89	37	4	CID011524144
Drug	AC1MHGE4	PPARA PPARD	1.54e-05	4	37	2	CID003025998
Drug	T0070907	PPARA PPARD HNF4A	1.72e-05	31	37	3	CID002777391
Drug	octadecenedioic acid	PPARA PPARD	2.56e-05	5	37	2	CID006440435
Drug	Dioctyl Sulfosuccinic Acid	PPARA PPARD	2.56e-05	5	37	2	ctd:D004143
Drug	2-ethylhexanoic acid	PPARA PPARD	2.56e-05	5	37	2	ctd:C040668
Drug	Heptanoic Acids	PPARA PPARD	2.56e-05	5	37	2	ctd:D006538
Drug	AC1L9JWY	PPARA PPARD	2.56e-05	5	37	2	CID000446639
Drug	L-165041	PPARA PPARD CREB1	2.72e-05	36	37	3	CID006603901
Drug	norathyriol	PPARA PPARD	3.84e-05	6	37	2	ctd:C069053
Drug	8-hydroxyeicosatetraenoic acid	PPARA PPARD	3.84e-05	6	37	2	ctd:C047628
Drug	BIX 02189	ATF1 CREB1	3.84e-05	6	37	2	ctd:C533207
Drug	ethyl(E,E,E)-7-(2-n-propoxy-5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-naphthalen-3-yl)-6-fluorp-3-methylocta-2,4,6-trienoate	PPARA PPARD	3.84e-05	6	37	2	ctd:C504648
Drug	Xamoterol	ATF1 CREB1	3.84e-05	6	37	2	ctd:D017307
Drug	GW2433	PPARA PPARD	3.84e-05	6	37	2	CID000001517
Drug	R)-4-yn-VPA	PPARA PPARD	3.84e-05	6	37	2	CID000115233
Drug	IN1304	PPARA PPARD CREB1	4.34e-05	42	37	3	CID004516886
Drug	amlodipine	TASP1 ATF6 ATF1 CREB1	5.13e-05	126	37	4	CID000002162
Drug	casticin	FAM227A ATF6 NOP58 PPARD CREB1	5.21e-05	252	37	5	ctd:C054133
Drug	LY 518674	PPARA PPARD	5.37e-05	7	37	2	ctd:C479889
Drug	ZNS 114-666	TASP1 ATF1 MSMB	6.91e-05	49	37	3	CID000409441
Drug	benzoxazinone analogue	PPARA PPARD	7.15e-05	8	37	2	CID000468715
Drug	PPAPs	PPARA PPARD	7.15e-05	8	37	2	CID009576869
Drug	Palmitoyl Coenzyme A	PPARA HNF4A	9.18e-05	9	37	2	ctd:D010171
Drug	monoisononylphthalate	PPARA PPARD	9.18e-05	9	37	2	ctd:C471400
Drug	DEAC	ATF1 CREB1 MATN2	9.78e-05	55	37	3	CID000007277
Drug	Fatty Acids, Nonesterified	ATF6 PPARA PPARD	1.03e-04	56	37	3	ctd:D005230
Drug	AC1NUP8U	PPARA PPARD	1.15e-04	10	37	2	CID005487216
Drug	15(S)-HETrE	PPARA PPARD	1.15e-04	10	37	2	CID000001437
Drug	mono-benzyl phthalate	PPARA PPARD	1.15e-04	10	37	2	ctd:C103325
Drug	1-(carboxymethylthio)tetradecane	PPARA PPARD	1.15e-04	10	37	2	ctd:C062078
Drug	Docosahexaenoic Acids	ATF1 PPARA PPARD CREB1	1.33e-04	161	37	4	ctd:D004281
Drug	Musk T	PPARA PPARD	1.40e-04	11	37	2	CID000061014
Drug	17-[2-hydroxy-6-methyl-1-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhept-5-en-2-yl]-3-[(2S,3R,4S,5S)-5-hydroxy-4-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3-[(2S,3R,4R,5S,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-4,4,8,14-tetramethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-10-carbaldehyde	PPARA PPARD	1.40e-04	11	37	2	CID011968562
Drug	Nicotinamide Mononucleotide	PPARA PPARD	1.40e-04	11	37	2	ctd:D009537
Drug	GW501516	PPARA PPARD	1.68e-04	12	37	2	CID009803963
Drug	Ertiprotafib	PPARA PPARD	1.68e-04	12	37	2	CID000157049
Drug	tetradecylselenoacetic acid	PPARA PPARD	1.68e-04	12	37	2	ctd:C410666
Drug	GW2331	PPARA PPARD	1.98e-04	13	37	2	CID000657048
Drug	2-bromopalmitate	PPARA PPARD	1.98e-04	13	37	2	ctd:C022776
Drug	Diphenhydramine hydrochloride [147-24-0]; Up 200; 13.8uM; PC3; HT_HG-U133A	KMT2B ZFYVE16 CREB1 GLG1	2.66e-04	193	37	4	1830_UP
Drug	retinoic acid; Down 200; 1uM; MCF7; HT_HG-U133A	TRAF5 KMT2B CREB1 GLG1	2.66e-04	193	37	4	6931_DN
Drug	AC1L9N9H	PPARA PPARD JMJD6	2.66e-04	77	37	3	CID000449572
Drug	methyl palmitate	PPARA PPARD	2.66e-04	15	37	2	CID000008181
Drug	Dipyridamole [58-32-2]; Down 200; 8uM; PC3; HG-U133A	UBA5 ATF6 ATF1 CREB1	2.76e-04	195	37	4	1934_DN
Drug	AC1L1BEH	PPARA PPARD HNF4A	2.76e-04	78	37	3	CID000001404
Drug	Trimeprazine tartrate [4330-99-8]; Down 200; 5.4uM; HL60; HT_HG-U133A	PPARA PPARD KMT2B GLG1	2.82e-04	196	37	4	2736_DN
Drug	Solasodine [126-17-0]; Down 200; 9.6uM; PC3; HT_HG-U133A	PPARA PPARD KMT2B GLG1	2.93e-04	198	37	4	3749_DN
Drug	Dichlorphenamide [120-97-8]; Up 200; 13.2uM; MCF7; HT_HG-U133A	KMT2B JMJD6 GLG1 MSMB	2.98e-04	199	37	4	5286_UP
Drug	4-(4-(3-(4-trifluoromethoxy-phenyl)ureido)cyclohexyloxy)benzoic acid	PPARA PPARD	3.04e-04	16	37	2	ctd:C572961
Drug	BM 17.0744	PPARA PPARD	3.04e-04	16	37	2	CID009929731
Drug	anti-oxLDL	PPARA PPARD	3.04e-04	16	37	2	CID003083542
Drug	12-Hydroxy-5,8,10,14-eicosatetraenoic Acid	PPARA PPARD	3.04e-04	16	37	2	ctd:D019377
Drug	Drugs, Chinese Herbal	CREBRF ATF6 CHD2 PPARA PPARD HNF4A	3.34e-04	586	37	6	ctd:D004365
Drug	GW0072	PPARA PPARD	3.44e-04	17	37	2	CID000449532
Drug	AC1NP8CI	PPARA PPARD	3.44e-04	17	37	2	CID005153863
Drug	JTT-501	PPARA PPARD	3.44e-04	17	37	2	CID000154000
Drug	MnCl2	ATF1 PPARD CREB1	3.68e-04	86	37	3	CID000024480
Drug	CV-1	PPARA PPARD HNF4A CREB1	3.86e-04	213	37	4	CID000130105
Drug	dodecylthioacetic acid	PPARA PPARD	3.87e-04	18	37	2	CID000083701
Drug	Arachidonic Acid	ATF1 PPARA PPARD CREB1	4.14e-04	217	37	4	ctd:D016718
Drug	AC1L419E	PPARA PPARD	4.32e-04	19	37	2	CID000099951
Drug	AC1L3G3T	PPARA PPARD HNF4A	4.64e-04	93	37	3	CID000114866
Drug	2'-deoxyuridine-5'-monophosphate	PPARA PPARD CREB1	4.78e-04	94	37	3	CID000000688
Drug	KRP-297	PPARA PPARD	4.79e-04	20	37	2	CID000151183
Drug	AC1L9K70	PPARA PPARD HNF4A CREB1	4.99e-04	228	37	4	CID000446871
Drug	2-ethylhexanoic acid	PPARA PPARD	5.29e-04	21	37	2	CID000008697
Drug	NSC726617	PPARA PPARD	5.29e-04	21	37	2	CID011360432
Drug	Mimosine	ATF1 CREB1	5.29e-04	21	37	2	ctd:D008898
Drug	34 C	CREB1 JMJD6	5.29e-04	21	37	2	CID000002084
Drug	noladin ether	PPARA PPARD	5.29e-04	21	37	2	CID006483057
Drug	BAY 11-7082	TASP1 TRAF5 CREB1	5.40e-04	98	37	3	CID000002301
Drug	Oleic Acid	PPARA PPARD HNF4A	5.40e-04	98	37	3	ctd:D019301
Drug	pitavastatin	PPARA PPARD	5.82e-04	22	37	2	ctd:C108475
Disease	Clear Cell Sarcoma of Soft Tissue	ATF1 CREB1	7.72e-06	4	34	2	C0206651
Disease	phospholipid measurement	ZNF600 PPARD HNF4A MUSK	2.02e-05	140	34	4	EFO_0004639
Disease	alkaline phosphatase measurement	SCUBE3 FAM227A NOP58 PPARA PPARD HNF4A MUSK	1.33e-04	1015	34	7	EFO_0004533
Disease	Cholecystitis	ZNF761 HNF4A	2.18e-04	19	34	2	HP_0001082
Disease	level of Sterol ester (27:1/18:2) in blood serum	HNF4A MUSK	4.12e-04	26	34	2	OBA_2045194
Disease	level of Sterol ester (27:1/16:0) in blood serum	HNF4A MUSK	4.12e-04	26	34	2	OBA_2045191
Disease	prostate cancer (implicated_via_orthology)	CHD2 MSMB	6.65e-04	33	34	2	DOID:10283 (implicated_via_orthology)
Disease	C-reactive protein measurement, high density lipoprotein cholesterol measurement	HNF4A MUSK	7.06e-04	34	34	2	EFO_0004458, EFO_0004612
Disease	neutrophil count	SCUBE3 ATF6 HNF4A JMJD6 GLG1 MUSK USP47	8.60e-04	1382	34	7	EFO_0004833
Disease	Cutaneous Melanoma	CREB1 JMJD6	1.03e-03	41	34	2	C0151779
Disease	mean corpuscular hemoglobin concentration	FAM227A NOP58 MRPL36 ZFAT CREB1 MUSK	1.49e-03	1105	34	6	EFO_0004528
Disease	sexual dimorphism measurement	SCUBE3 ATF1 ZFAT PPARD KMT2B HNF4A	1.50e-03	1106	34	6	EFO_0021796
Disease	omega-6 polyunsaturated fatty acid measurement	PPARD HNF4A MUSK	1.51e-03	197	34	3	EFO_0005680
Disease	triacylglycerol 52:2 measurement	ZFAT MUSK	1.84e-03	55	34	2	EFO_0010414
Disease	free cholesterol to total lipids in medium HDL percentage	HNF4A MUSK	2.19e-03	60	34	2	EFO_0022282
Disease	Non-alcoholic Fatty Liver Disease	PPARA PPARD	2.96e-03	70	34	2	C0400966
Disease	Nonalcoholic Steatohepatitis	PPARA PPARD	2.96e-03	70	34	2	C3241937
Disease	phospholipids in large HDL measurement	HNF4A MUSK	3.22e-03	73	34	2	EFO_0022190
Disease	granulocyte percentage of myeloid white cells	SCUBE3 GLG1 MUSK	3.60e-03	268	34	3	EFO_0007997
Disease	total iron binding capacity	UBA5 MUSK	3.66e-03	78	34	2	EFO_0006334
Disease	sphingomyelin measurement	TASP1 HNF4A MUSK	3.99e-03	278	34	3	EFO_0010118
Disease	Cardiac Hypertrophy	PPARA PPARD	4.04e-03	82	34	2	C1383860
Disease	Epilepsy, Cryptogenic	CHD2 PCDH19	4.04e-03	82	34	2	C0086237
Disease	Cardiomegaly	PPARA PPARD	4.04e-03	82	34	2	C0018800

Protein segments in the cluster

Peptide	Gene	Start	Entry
NKRKKCVRDCEKYKP	ADNP	806	Q9H2P0
EDKVKRQRKSQYSCK	FAM227A	96	F5H4B4
RACRLKKKAQYEANK	CREBRF	536	Q8IUR6
NRESACQSRKKKKEY	ATF6	316	P18850
DKKACQFKRSFLKNC	ATP1B4	216	Q9UN42
IKCKRDNKEIRTYNC	PCDH19	701	Q8TAB3
NLTYCKCLQKVGDRK	NOP58	201	Q9Y2X3
KRKYRNQKFKCGEDN	JMJD6	91	Q6NYC1
DKKTCRRINYCALNK	MATN2	396	O00339
KDKRNQCRYCRLKKC	HNF4A	106	P41235
KKQCCVYRKCDKIEA	KMT2B	996	Q9UMN6
KEECQDRVTQCKYKR	CYHR1	156	Q6ZMK1
KDNCQRIFKKEDCKY	MSMB	81	P08118
CKSDLKKYRCNVENL	GLG1	376	Q92896
EEKKKYCLTCRVKAA	CHD2	1241	O14647
CRRKKKEYVKCLENR	CREB1	286	P16220
CSCKKGYKLLINERN	SCUBE3	301	Q8IX30
YDKCDRSCKIQKKNR	PPARA	136	Q07869
RSCKIQKKNRNKCQY	PPARA	141	Q07869
QKKNRNKCQYCRFHK	PPARA	146	Q07869
FKNKTVLKKRCKDCY	MRPL36	66	Q9P0J6
CKRCKKSFALKSYLN	SCRT1	306	Q9BWW7
LEYEKCERSCKIQKK	PPARD	106	Q03181
KIQKKNRNKCQYCRF	PPARD	116	Q03181
CQFRKEKCLYCKKDV	TRAF5	161	O00463
AARECRRKKKEYVKC	ATF1	226	P18846
KQYKCDVCDKVFIRK	ZNF525	241	Q8N782
CRFCKKKYSDVKNLI	ZFAT	356	Q9P243
KYKCDVCGKLFNQKR	ZNF761	241	Q86XN6
QTNKIKCRRCEKYNC	TCEANC	291	Q8N8B7
RNCRKQQEEYKKKVA	UBA5	306	Q9GZZ9
QYFCERCKKKCDARK	USP47	361	Q96K76
KQYKCDVCGKVFNRK	ZNF813	241	Q6ZN06
KLYKCETCDKVFSRK	ZNF600	636	Q6ZNG1
KKTCECNQCEKAFRK	ZNF559	116	Q9BR84
SKAKEYKHVCKRACQ	TASP1	56	Q9H6P5
YKHVCKRACQKAIEK	TASP1	61	Q9H6P5
CTNKCSKAFRCKDKN	WFDC11	51	Q8NEX6
KLYKCSECEKTFRKQ	ZNF501	216	Q96CX3
YDREKISECKKCRKI	ZNF461	186	Q8TAF7
CNRKCKLQYLEKEAR	ZFYVE16	781	Q7Z3T8
YCCRRRKQWKNKKRE	MUSK	516	O15146