| GeneOntologyMolecularFunction | olfactory receptor activity | OR5D16 OR2T29 OR8J2 OR8D2 OR8B4 OR4C6 OR10P1 OR13C8 OR13C3 OR6Q1 OR13C4 OR9Q1 OR10Q1 OR2G3 OR4E1 OR4C45 OR14J1 OR8H1 OR2T5 OR14C36 OR10Z1 OR6N1 OR10D3 OR6A2 OR5J2 OR13C9 OR56B1 OR52N5 OR10K1 OR4C46 OR4C13 OR8B12 OR4F21 OR4D5 OR6T1 OR4X1 OR4K3 OR6B2 GPR148 OR5F1 | 1.26e-37 | 431 | 115 | 40 | GO:0004984 |
| GeneOntologyMolecularFunction | G protein-coupled receptor activity | VN1R2 TBXA2R OR5D16 ADGRG5 OR2T29 OR8J2 GPR12 HTR1B OR8D2 OR8B4 HTR4 OR4C6 OR10P1 OR13C8 OR13C3 OR6Q1 OR13C4 OR9Q1 OR10Q1 OR2G3 OR4E1 OR4C45 TAAR2 OR14J1 OR8H1 OR2T5 OR14C36 ADGRA2 OR10Z1 OR6N1 OR10D3 OR6A2 OR5J2 OR13C9 OR56B1 GPR75 OR52N5 OR10K1 OR4C46 OR4C13 OR8B12 OR4F21 OR4D5 OR6T1 OR4X1 OR4K3 OR6B2 GPR148 OR5F1 | 6.91e-36 | 884 | 115 | 49 | GO:0004930 |
| GeneOntologyMolecularFunction | transmembrane signaling receptor activity | VN1R2 TBXA2R OR5D16 ADGRG5 OR2T29 OR8J2 GPR12 HTR1B OR8D2 OR8B4 HTR4 OR4C6 OR10P1 OR13C8 OR13C3 OR6Q1 OR13C4 OR9Q1 MFSD6 OR10Q1 OR2G3 OR4E1 OR4C45 TAAR2 OR14J1 GRIA4 OR8H1 OR2T5 OR14C36 ADGRA2 OR10Z1 OR6N1 OR10D3 OR6A2 OR5J2 OR13C9 OR56B1 GPR75 TLR4 OR52N5 OR10K1 OR4C46 OR4C13 OR8B12 OR4F21 OR4D5 OR6T1 OR4X1 OR4K3 OR6B2 GPR148 OR5F1 | 1.80e-30 | 1353 | 115 | 52 | GO:0004888 |
| GeneOntologyMolecularFunction | odorant binding | VN1R2 OR5D16 OR8J2 OR8D2 OR8B4 OR9Q1 OR10Q1 OR4E1 OR14J1 OR8H1 OR14C36 OR10Z1 OR5J2 OR10K1 OR8B12 OR6B2 GPR148 OR5F1 | 2.37e-20 | 127 | 115 | 18 | GO:0005549 |
| GeneOntologyMolecularFunction | type III transforming growth factor beta receptor binding | TGFB2 TGFB3 | 1.96e-04 | 4 | 115 | 2 | GO:0034714 |
| GeneOntologyBiologicalProcess | detection of chemical stimulus involved in sensory perception of smell | OR5D16 OR2T29 OR8J2 OR8D2 OR8B4 OR4C6 OR10P1 OR13C8 OR13C3 OR6Q1 OR13C4 OR9Q1 OR10Q1 OR2G3 OR4E1 OR4C45 OR14J1 OR8H1 OR2T5 OR14C36 OR10Z1 OR6N1 OR10D3 OR6A2 OR5J2 OR13C9 OR56B1 OR52N5 OR10K1 OR4C46 OR4C13 OR8B12 OR4F21 OR4D5 OR6T1 OR4X1 OR4K3 OR6B2 GPR148 OR5F1 | 3.97e-38 | 432 | 115 | 40 | GO:0050911 |
| GeneOntologyBiologicalProcess | detection of chemical stimulus | OR5D16 OR2T29 OR8J2 OR8D2 OR8B4 OR4C6 OR10P1 OR13C8 OR13C3 OR6Q1 OR13C4 OR9Q1 OR10Q1 OR2G3 OR4E1 OR4C45 OR14J1 OR8H1 OR2T5 OR14C36 OR10Z1 OR6N1 OR10D3 TGFB3 OR6A2 OR5J2 OR13C9 OR56B1 TLR4 OR52N5 OR10K1 OR4C46 OR4C13 OR8B12 OR4F21 OR4D5 OR6T1 OR4X1 OR4K3 OR6B2 GPR148 OR5F1 | 1.68e-37 | 524 | 115 | 42 | GO:0009593 |
| GeneOntologyBiologicalProcess | sensory perception of smell | OR5D16 OR2T29 OR8J2 OR8D2 OR8B4 OR4C6 OR10P1 OR13C8 OR13C3 OR6Q1 OR13C4 OR9Q1 OR10Q1 OR2G3 OR4E1 OR4C45 OR14J1 OR8H1 OR2T5 OR14C36 OR10Z1 OR6N1 OR10D3 OR6A2 OR5J2 OR13C9 OR56B1 OR52N5 OR10K1 OR4C46 OR4C13 OR8B12 OR4F21 OR4D5 OR6T1 OR4X1 OR4K3 OR6B2 GPR148 OR5F1 | 7.66e-37 | 465 | 115 | 40 | GO:0007608 |
| GeneOntologyBiologicalProcess | detection of chemical stimulus involved in sensory perception | OR5D16 OR2T29 OR8J2 OR8D2 OR8B4 OR4C6 OR10P1 OR13C8 OR13C3 OR6Q1 OR13C4 OR9Q1 OR10Q1 OR2G3 OR4E1 OR4C45 OR14J1 OR8H1 OR2T5 OR14C36 OR10Z1 OR6N1 OR10D3 OR6A2 OR5J2 OR13C9 OR56B1 OR52N5 OR10K1 OR4C46 OR4C13 OR8B12 OR4F21 OR4D5 OR6T1 OR4X1 OR4K3 OR6B2 GPR148 OR5F1 | 4.13e-36 | 485 | 115 | 40 | GO:0050907 |
| GeneOntologyBiologicalProcess | sensory perception of chemical stimulus | VN1R2 OR5D16 OR2T29 OR8J2 OR8D2 OR8B4 OR4C6 OR10P1 OR13C8 OR13C3 OR6Q1 OR13C4 OR9Q1 OR10Q1 OR2G3 OR4E1 OR4C45 OR14J1 OR8H1 OR2T5 OR14C36 OR10Z1 OR6N1 OR10D3 OR6A2 OR5J2 OR13C9 OR56B1 OR52N5 OR10K1 OR4C46 OR4C13 OR8B12 OR4F21 OR4D5 OR6T1 OR4X1 OR4K3 OR6B2 GPR148 OR5F1 | 2.27e-35 | 547 | 115 | 41 | GO:0007606 |
| GeneOntologyBiologicalProcess | detection of stimulus involved in sensory perception | OR5D16 OR2T29 OR8J2 OR8D2 OR8B4 OR4C6 OR10P1 OR13C8 OR13C3 OR6Q1 OR13C4 OR9Q1 OR10Q1 OR2G3 OR4E1 OR4C45 OR14J1 OR8H1 OR2T5 OR14C36 OR10Z1 OR6N1 OR10D3 OR6A2 OR5J2 OR13C9 OR56B1 TLR4 OR52N5 OR10K1 OR4C46 OR4C13 OR8B12 OR4F21 OR4D5 OR6T1 OR4X1 OR4K3 OR6B2 GPR148 OR5F1 | 2.80e-34 | 582 | 115 | 41 | GO:0050906 |
| GeneOntologyBiologicalProcess | detection of stimulus | OR5D16 OR2T29 OR8J2 OR8D2 OR8B4 OR4C6 OR10P1 OR13C8 OR13C3 OR6Q1 OR13C4 OR9Q1 OR10Q1 OR2G3 OR4E1 OR4C45 OR14J1 OR8H1 OR2T5 OR14C36 OR10Z1 OR6N1 OR10D3 TGFB3 OR6A2 OR5J2 OR13C9 OR56B1 TLR4 OR52N5 OR10K1 OR4C46 OR4C13 OR8B12 OR4F21 OR4D5 OR6T1 OR4X1 OR4K3 OR6B2 GPR148 OR5F1 | 9.34e-32 | 722 | 115 | 42 | GO:0051606 |
| GeneOntologyBiologicalProcess | G protein-coupled receptor signaling pathway | VN1R2 TBXA2R OR5D16 ADGRG5 OR2T29 OR8J2 GPR12 HTR1B OR8D2 OR8B4 HTR4 OR4C6 OR10P1 OR13C8 OR13C3 OR6Q1 OR13C4 OR9Q1 OR10Q1 OR2G3 OR4E1 OR4C45 TAAR2 OR14J1 OR8H1 OR2T5 OR14C36 ADGRA2 ADCY2 RGS3 OR10Z1 OR6N1 OR10D3 ORAI1 OR6A2 OR5J2 OR13C9 OR56B1 GPR75 OR52N5 OR10K1 OR4C46 OR4C13 OR8B12 OR4F21 GNB3 OR4D5 OR6T1 OR4X1 OR4K3 OR6B2 GPR148 OR5F1 | 1.40e-31 | 1395 | 115 | 53 | GO:0007186 |
| GeneOntologyBiologicalProcess | sensory perception | VN1R2 OR5D16 OR2T29 OR8J2 OR8D2 OR8B4 OR4C6 OR10P1 OR13C8 OR13C3 OR6Q1 OR13C4 OR9Q1 OR10Q1 OR2G3 OR4E1 OR4C45 OR14J1 OR8H1 OR2T5 OR14C36 OR10Z1 OR6N1 OR10D3 OR6A2 OR5J2 OR13C9 OR56B1 TLR4 OR52N5 OR10K1 OR4C46 SLC45A2 OR4C13 OR8B12 OR4F21 OR4D5 OR6T1 OR4X1 OR4K3 OR6B2 GPR148 OR5F1 | 5.72e-26 | 1072 | 115 | 43 | GO:0007600 |
| GeneOntologyBiologicalProcess | uterine wall breakdown | TGFB2 TGFB3 | 3.08e-05 | 2 | 115 | 2 | GO:0042704 |
| Domain | GPCR_Rhodpsn_7TM | VN1R2 TBXA2R OR5D16 OR2T29 GPR12 HTR1B OR8D2 OR8B4 HTR4 OR4C6 OR10P1 OR13C8 OR13C3 OR6Q1 OR13C4 OR9Q1 OR10Q1 OR2G3 TAAR2 OR14J1 OR8H1 OR2T5 OR14C36 OR10Z1 OR6N1 OR6A2 OR5J2 OR13C9 OR56B1 GPR75 OR52N5 OR10K1 OR4C46 OR4C13 OR8B12 OR4F21 OR4D5 OR6T1 OR4X1 OR6B2 GPR148 OR5F1 | 4.09e-32 | 670 | 111 | 42 | IPR017452 |
| Domain | G_PROTEIN_RECEP_F1_1 | VN1R2 TBXA2R OR5D16 OR2T29 GPR12 HTR1B OR8D2 OR8B4 HTR4 OR4C6 OR10P1 OR13C8 OR13C3 OR6Q1 OR13C4 OR9Q1 OR10Q1 OR2G3 TAAR2 OR14J1 OR8H1 OR2T5 OR14C36 OR10Z1 OR6N1 OR6A2 OR5J2 OR13C9 OR56B1 GPR75 OR52N5 OR10K1 OR4C46 OR4C13 OR8B12 OR4F21 OR4D5 OR6T1 OR4X1 OR6B2 GPR148 OR5F1 | 1.01e-31 | 685 | 111 | 42 | PS00237 |
| Domain | G_PROTEIN_RECEP_F1_2 | VN1R2 TBXA2R OR5D16 OR2T29 GPR12 HTR1B OR8D2 OR8B4 HTR4 OR4C6 OR10P1 OR13C8 OR13C3 OR6Q1 OR13C4 OR9Q1 OR10Q1 OR2G3 TAAR2 OR14J1 OR8H1 OR2T5 OR14C36 OR10Z1 OR6N1 OR6A2 OR5J2 OR13C9 OR56B1 GPR75 OR52N5 OR10K1 OR4C46 OR4C13 OR8B12 OR4F21 OR4D5 OR6T1 OR4X1 OR6B2 GPR148 OR5F1 | 1.44e-31 | 691 | 111 | 42 | PS50262 |
| Domain | GPCR_Rhodpsn | VN1R2 TBXA2R OR5D16 OR2T29 GPR12 HTR1B OR8D2 OR8B4 HTR4 OR4C6 OR10P1 OR13C8 OR13C3 OR6Q1 OR13C4 OR9Q1 OR10Q1 OR2G3 TAAR2 OR14J1 OR8H1 OR2T5 OR14C36 OR10Z1 OR6N1 OR6A2 OR5J2 OR13C9 OR56B1 GPR75 OR52N5 OR10K1 OR4C46 OR4C13 OR8B12 OR4F21 OR4D5 OR6T1 OR4X1 OR6B2 GPR148 OR5F1 | 1.53e-31 | 692 | 111 | 42 | IPR000276 |
| Domain | 7tm_1 | TBXA2R OR5D16 OR2T29 GPR12 HTR1B OR8D2 OR8B4 HTR4 OR4C6 OR10P1 OR13C8 OR13C3 OR6Q1 OR13C4 OR9Q1 OR10Q1 OR2G3 TAAR2 OR14J1 OR8H1 OR2T5 OR14C36 OR10Z1 OR6N1 OR6A2 OR5J2 OR13C9 OR56B1 GPR75 OR52N5 OR10K1 OR4C46 OR4C13 OR8B12 OR4F21 OR4D5 OR6T1 OR4X1 OR6B2 GPR148 OR5F1 | 1.06e-30 | 677 | 111 | 41 | PF00001 |
| Domain | Olfact_rcpt | OR5D16 OR2T29 OR8D2 OR8B4 OR4C6 OR10P1 OR13C8 OR13C3 OR6Q1 OR13C4 OR9Q1 OR10Q1 OR2G3 OR14J1 OR8H1 OR2T5 OR14C36 OR10Z1 OR6N1 OR6A2 OR5J2 OR13C9 OR56B1 OR52N5 OR10K1 OR4C46 OR4C13 OR8B12 OR4F21 OR4D5 OR6T1 OR4X1 OR6B2 OR5F1 | 2.19e-30 | 393 | 111 | 34 | IPR000725 |
| Domain | Med13_N | MED13L MED13 | 3.50e-05 | 2 | 111 | 2 | PF11597 |
| Domain | Mediator_Med13_N_met/fun | MED13L MED13 | 3.50e-05 | 2 | 111 | 2 | IPR021643 |
| Domain | Mediator_Med13 | MED13L MED13 | 3.50e-05 | 2 | 111 | 2 | IPR009401 |
| Domain | Med13_C | MED13L MED13 | 3.50e-05 | 2 | 111 | 2 | PF06333 |
| Domain | CRAC_channel | ORAI1 ORAI3 | 1.05e-04 | 3 | 111 | 2 | IPR012446 |
| Domain | TGF-beta | TGFB2 TGFB3 | 1.05e-04 | 3 | 111 | 2 | IPR016319 |
| Domain | Orai-1 | ORAI1 ORAI3 | 1.05e-04 | 3 | 111 | 2 | PF07856 |
| Domain | 7TM_GPCR_Srsx | GPR12 HTR1B HTR4 TAAR2 OR56B1 | 5.48e-04 | 112 | 111 | 5 | SM01381 |
| Pathway | REACTOME_OLFACTORY_SIGNALING_PATHWAY | OR5D16 OR2T29 OR8J2 OR8D2 OR8B4 OR4C6 OR10P1 OR13C8 OR13C3 OR6Q1 OR13C4 OR9Q1 OR10Q1 OR2G3 OR4E1 OR4C45 OR14J1 OR8H1 OR2T5 OR14C36 OR10Z1 OR6N1 OR10D3 OR6A2 OR5J2 OR13C9 OR56B1 OR52N5 OR10K1 OR4C46 OR4C13 OR8B12 OR4F21 OR4D5 OR6T1 OR4X1 OR4K3 OR6B2 OR5F1 | 4.39e-34 | 417 | 99 | 39 | M4072 |
| Pathway | KEGG_OLFACTORY_TRANSDUCTION | OR5D16 OR2T29 OR8D2 OR8B4 OR4C6 OR10P1 OR13C8 OR13C3 OR6Q1 OR13C4 OR9Q1 OR10Q1 OR2G3 OR4C45 OR14J1 OR8H1 OR2T5 OR14C36 OR10Z1 OR6N1 OR6A2 OR5J2 OR13C9 OR56B1 OR52N5 OR10K1 OR4C46 OR4C13 OR8B12 OR4D5 OR6T1 OR4X1 OR6B2 OR5F1 | 1.74e-28 | 389 | 99 | 34 | M14091 |
| Pathway | REACTOME_SENSORY_PERCEPTION | OR5D16 OR2T29 OR8J2 OR8D2 OR8B4 OR4C6 OR10P1 OR13C8 OR13C3 OR6Q1 OR13C4 OR9Q1 OR10Q1 OR2G3 OR4E1 OR4C45 OR14J1 OR8H1 OR2T5 OR14C36 OR10Z1 OR6N1 OR10D3 OR6A2 OR5J2 OR13C9 OR56B1 OR52N5 OR10K1 OR4C46 OR4C13 OR8B12 OR4F21 GNB3 OR4D5 OR6T1 OR4X1 OR4K3 OR6B2 OR5F1 | 3.06e-28 | 636 | 99 | 40 | M41834 |
| Pathway | WP_GPCRS_CLASS_A_RHODOPSINLIKE | TBXA2R GPR12 HTR1B OR8D2 OR8B4 HTR4 OR6A2 OR8B12 | 4.86e-05 | 186 | 99 | 8 | MM15994 |
| Pathway | WP_GPCRS_CLASS_A_RHODOPSINLIKE | TBXA2R GPR12 HTR1B OR8D2 HTR4 OR14J1 OR6A2 GPR75 OR5F1 | 8.76e-05 | 260 | 99 | 9 | M39397 |
| Pathway | WP_GPCRS_ODORANT | ADGRG5 GPR12 TAAR2 ADGRA2 OR10D3 OR5J2 GPR75 | 1.17e-04 | 157 | 99 | 7 | MM15872 |
| Pathway | WP_PLATELETMEDIATED_INTERACTIONS_WITH_VASCULAR_AND_CIRCULATING_CELLS | TGFB2 TGFB3 TLR4 | 2.13e-04 | 17 | 99 | 3 | M39807 |
| Pubmed | Different evolutionary processes shaped the mouse and human olfactory receptor gene families. | OR5D16 OR2T29 OR8D2 OR8B4 OR4C6 OR10P1 OR13C8 OR13C3 OR9Q1 OR10Q1 OR4E1 OR4C45 OR14J1 OR8H1 OR2T5 OR14C36 OR10Z1 OR6N1 OR10D3 OR6A2 OR5J2 OR56B1 OR52N5 OR10K1 OR4C46 OR4C13 OR8B12 OR4F21 OR4D5 OR6B2 | 3.44e-34 | 340 | 116 | 30 | 11875048 |
| Pubmed | The olfactory receptor gene superfamily of the mouse. | OR5D16 OR2T29 OR8D2 OR8B4 OR4C6 OR10P1 OR13C8 OR13C3 OR9Q1 OR10Q1 OR4E1 OR4C45 OR14J1 OR8H1 OR2T5 OR14C36 OR10Z1 OR6N1 OR10D3 OR6A2 OR5J2 OR56B1 OR52N5 OR10K1 OR4C46 OR4C13 OR8B12 OR4F21 OR4D5 OR6B2 | 3.44e-34 | 340 | 116 | 30 | 11802173 |
| Pubmed | A unified nomenclature for vertebrate olfactory receptors. | OR5D16 OR2T29 OR8D2 OR8B4 OR4C6 OR10P1 OR13C8 OR13C3 OR9Q1 OR10Q1 OR4E1 OR4C45 OR14J1 OR8H1 OR2T5 OR14C36 OR10Z1 OR6N1 OR10D3 OR6A2 OR5J2 OR56B1 OR52N5 OR10K1 OR4C46 OR4C13 OR8B12 OR4F21 OR4D5 OR6B2 | 4.50e-34 | 343 | 116 | 30 | 32295537 |
| Pubmed | Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels. | OR5D16 OR2T29 OR8D2 OR8B4 OR4C6 OR10P1 OR13C8 OR13C3 OR9Q1 OR10Q1 OR4E1 OR4C45 OR14J1 OR8H1 OR2T5 OR14C36 OR10Z1 OR6N1 OR10D3 OR6A2 OR5J2 OR56B1 OR52N5 OR10K1 OR4C46 OR4C13 OR8B12 OR4F21 OR4D5 OR6B2 | 5.86e-34 | 346 | 116 | 30 | 14611657 |
| Pubmed | The human olfactory receptor gene family. | OR5D16 OR8D2 OR8B4 OR4C6 OR10P1 OR13C8 OR13C3 OR6Q1 OR13C4 OR10Q1 OR2G3 OR4E1 OR14J1 OR8H1 OR2T5 OR14C36 OR10Z1 OR6N1 OR10D3 OR6A2 OR5J2 OR13C9 OR56B1 OR52N5 OR10K1 OR4C13 OR8B12 OR4D5 OR6T1 OR4X1 OR4K3 OR6B2 OR5F1 | 2.43e-32 | 541 | 116 | 33 | 14983052 |
| Pubmed | DEFOG: a practical scheme for deciphering families of genes. | OR5D16 OR8B4 OR10P1 OR13C8 OR6Q1 OR13C4 OR9Q1 OR4E1 OR6N1 OR4C13 OR8B12 OR4K3 OR5F1 | 5.32e-13 | 219 | 116 | 13 | 12213199 |
| Pubmed | Odorant and vomeronasal receptor genes in two mouse genome assemblies. | OR2T29 OR8D2 OR4E1 OR2T5 OR14C36 OR56B1 OR4F21 | 5.72e-09 | 74 | 116 | 7 | 15081110 |
| Pubmed | Organization and evolutionary relatedness of OR37 olfactory receptor genes in mouse and human. | OR13C8 OR13C3 OR13C4 OR13C9 | 5.70e-08 | 12 | 116 | 4 | 12906860 |
| Pubmed | Personal receptor repertoires: olfaction as a model. | OR8J2 OR8D2 OR8B4 OR6Q1 OR4X1 | 1.74e-07 | 38 | 116 | 5 | 22908908 |
| Pubmed | Emx2 stimulates odorant receptor gene expression. | OR13C8 OR13C3 OR4E1 OR6A2 | 2.70e-07 | 17 | 116 | 4 | 18854508 |
| Pubmed | A dual-activity topoisomerase complex regulates mRNA translation and turnover. | ZNF384 HIP1 SZT2 CTC1 MYO9B MED13L TRRAP ADGRA2 ORAI1 THADA MDN1 DIP2C ESPL1 MED13 ATPAF2 | 4.25e-06 | 1105 | 116 | 15 | 35748872 |
| Pubmed | Characterization of a cluster comprising approximately 100 odorant receptor genes in mouse. | OR8D2 OR8B4 OR8B12 | 4.26e-06 | 10 | 116 | 3 | 11130974 |
| Pubmed | A probabilistic classifier for olfactory receptor pseudogenes. | OR8D2 OR8B4 OR6Q1 OR4X1 | 5.68e-06 | 35 | 116 | 4 | 16939646 |
| Pubmed | Plasticity in Ca2+ selectivity of Orai1/Orai3 heteromeric channel. | ORAI1 ORAI3 | 1.10e-05 | 2 | 116 | 2 | 19887627 |
| Pubmed | Differential Redox Regulation of Ca²⁺ Signaling and Viability in Normal and Malignant Prostate Cells. | ORAI1 ORAI3 | 1.10e-05 | 2 | 116 | 2 | 26445441 |
| Pubmed | Communication between N terminus and loop2 tunes Orai activation. | ORAI1 ORAI3 | 1.10e-05 | 2 | 116 | 2 | 29237733 |
| Pubmed | Odorant receptor proteins in the mouse main olfactory epithelium and olfactory bulb. | OR4E1 OR6A2 | 1.10e-05 | 2 | 116 | 2 | 28057532 |
| Pubmed | Immunohistochemical localization of members of the transforming growth factor (TGF)-beta superfamily in normal human salivary glands and pleomorphic adenomas. | TGFB2 TGFB3 | 1.10e-05 | 2 | 116 | 2 | 11488419 |
| Pubmed | Expression of transforming growth factor-beta isoforms (beta 2 and beta 3) in the mouse uterus: analysis of the periimplantation period and effects of ovarian steroids. | TGFB2 TGFB3 | 1.10e-05 | 2 | 116 | 2 | 1375903 |
| Pubmed | Store-dependent and -independent modes regulating Ca2+ release-activated Ca2+ channel activity of human Orai1 and Orai3. | ORAI1 ORAI3 | 1.10e-05 | 2 | 116 | 2 | 18420579 |
| Pubmed | A novel native store-operated calcium channel encoded by Orai3: selective requirement of Orai3 versus Orai1 in estrogen receptor-positive versus estrogen receptor-negative breast cancer cells. | ORAI1 ORAI3 | 1.10e-05 | 2 | 116 | 2 | 20395295 |
| Pubmed | Mediator complex component MED13 regulates zygotic genome activation and is required for postimplantation development in the mouse. | MED13L MED13 | 1.10e-05 | 2 | 116 | 2 | 29325037 |
| Pubmed | Disease-related quantitation of TGF-beta3 in human aqueous humor. | TGFB2 TGFB3 | 1.10e-05 | 2 | 116 | 2 | 18049952 |
| Pubmed | Both Orai1 and Orai3 are essential components of the arachidonate-regulated Ca2+-selective (ARC) channels. | ORAI1 ORAI3 | 1.10e-05 | 2 | 116 | 2 | 17991693 |
| Pubmed | Are Orai1 and Orai3 channels more important than calcium influx for cell proliferation? | ORAI1 ORAI3 | 1.10e-05 | 2 | 116 | 2 | 24321771 |
| Pubmed | Differential redox regulation of ORAI ion channels: a mechanism to tune cellular calcium signaling. | ORAI1 ORAI3 | 1.10e-05 | 2 | 116 | 2 | 20354224 |
| Pubmed | Facilitation of Orai3 targeting and store-operated function by Orai1. | ORAI1 ORAI3 | 1.10e-05 | 2 | 116 | 2 | 25791427 |
| Pubmed | The role of transforming growth factor beta-2, beta-3 in mediating apoptosis in the murine intestinal mucosa. | TGFB2 TGFB3 | 1.10e-05 | 2 | 116 | 2 | 11984523 |
| Pubmed | Orai1 and Orai3 act through distinct signalling axes to promote stemness and tumorigenicity of breast cancer stem cells. | ORAI1 ORAI3 | 1.10e-05 | 2 | 116 | 2 | 39135143 |
| Pubmed | Chromosomal location-dependent nonstochastic onset of odor receptor expression. | OR8B4 OR4E1 OR6A2 | 2.38e-05 | 17 | 116 | 3 | 20668191 |
| Pubmed | Studies of TGF-beta(1-3) in serosal fluid during abdominal surgery and their effect on in vitro human mesothelial cell proliferation. | TGFB2 TGFB3 | 3.30e-05 | 3 | 116 | 2 | 19062040 |
| Pubmed | Activity-dependent release of transforming growth factor-beta in a neuronal network in vitro. | TGFB2 TGFB3 | 3.30e-05 | 3 | 116 | 2 | 17997227 |
| Pubmed | Analysis of HCRTR2, GNB3, and ADH4 Gene Polymorphisms in a Southeastern European Caucasian Cluster Headache Population. | ADH4 GNB3 | 3.30e-05 | 3 | 116 | 2 | 31768945 |
| Pubmed | Remodeling of channel-forming ORAI proteins determines an oncogenic switch in prostate cancer. | ORAI1 ORAI3 | 3.30e-05 | 3 | 116 | 2 | 24954132 |
| Pubmed | Murine ORAI2 splice variants form functional Ca2+ release-activated Ca2+ (CRAC) channels. | ORAI1 ORAI3 | 3.30e-05 | 3 | 116 | 2 | 17463004 |
| Pubmed | TGF-beta knockout and dominant-negative receptor transgenic mice. | TGFB2 TGFB3 | 3.30e-05 | 3 | 116 | 2 | 9525700 |
| Pubmed | Differential expression of transforming growth factor-beta isoforms in bullous keratopathy corneas. | TGFB2 TGFB3 | 3.30e-05 | 3 | 116 | 2 | 20142847 |
| Pubmed | TGF-beta is required for programmed cell death in interdigital webs of the developing mouse limb. | TGFB2 TGFB3 | 3.30e-05 | 3 | 116 | 2 | 11960699 |
| Pubmed | Authentic CRAC channel activity requires STIM1 and the conserved portion of the Orai N terminus. | ORAI1 ORAI3 | 3.30e-05 | 3 | 116 | 2 | 29237734 |
| Pubmed | Down-regulation effects of IFN-α on p11, 5-htr1b and 5-HTR4 protein levels were affected by NH4CL or MG132 treatment in SH-sy5y cells. | HTR1B HTR4 | 3.30e-05 | 3 | 116 | 2 | 31502579 |
| Pubmed | Posttraumatic temporal TGF-β mRNA expression in lens epithelial cells of paediatric patients. | TGFB2 TGFB3 | 3.30e-05 | 3 | 116 | 2 | 22464821 |
| Pubmed | Expression of transforming growth factor-beta 1, -beta 2, and -beta 3 in human developing teeth: immunolocalization according to the odontogenesis phases. | TGFB2 TGFB3 | 3.30e-05 | 3 | 116 | 2 | 18078367 |
| Pubmed | CRACM1, CRACM2, and CRACM3 are store-operated Ca2+ channels with distinct functional properties. | ORAI1 ORAI3 | 3.30e-05 | 3 | 116 | 2 | 17442569 |
| Pubmed | Excess TGF-β mediates muscle weakness associated with bone metastases in mice. | TGFB2 TGFB3 | 3.30e-05 | 3 | 116 | 2 | 26457758 |
| Pubmed | Calcium inhibition and calcium potentiation of Orai1, Orai2, and Orai3 calcium release-activated calcium channels. | ORAI1 ORAI3 | 3.30e-05 | 3 | 116 | 2 | 17452328 |
| Pubmed | Specific transforming growth factor-beta subtypes regulate embryonic mouse Meckel's cartilage and tooth development. | TGFB2 TGFB3 | 3.30e-05 | 3 | 116 | 2 | 8125201 |
| Pubmed | Experimental manipulation of transforming growth factor-beta isoforms significantly affects adhesion formation in a murine surgical model. | TGFB2 TGFB3 | 3.30e-05 | 3 | 116 | 2 | 16192636 |
| Pubmed | Differential expression of TGF beta isoforms in murine palatogenesis. | TGFB2 TGFB3 | 3.30e-05 | 3 | 116 | 2 | 2401212 |
| Pubmed | Tgfbeta2 and 3 are coexpressed with their extracellular regulator Ltbp1 in the early limb bud and modulate mesodermal outgrowth and BMP signaling in chicken embryos. | TGFB2 TGFB3 | 3.30e-05 | 3 | 116 | 2 | 20565961 |
| Pubmed | Isoform-specific effects of transforming growth factor β on endothelial-to-mesenchymal transition. | TGFB2 TGFB3 | 3.30e-05 | 3 | 116 | 2 | 29856065 |
| Pubmed | Transforming growth factor-beta gene polymorphisms in sarcoidosis patients with and without fibrosis. | TGFB2 TGFB3 | 3.30e-05 | 3 | 116 | 2 | 16778279 |
| Pubmed | Transforming growth factor beta (TGFbeta1, TGFbeta2 and TGFbeta3) null-mutant phenotypes in embryonic gonadal development. | TGFB2 TGFB3 | 3.30e-05 | 3 | 116 | 2 | 18790002 |
| Pubmed | Transforming growth factor-beta isoform and receptor expression in chondrosarcoma of bone. | TGFB2 TGFB3 | 3.30e-05 | 3 | 116 | 2 | 12021923 |
| Pubmed | Differential expression of TGFβ isoforms in breast cancer highlights different roles during breast cancer progression. | TGFB2 TGFB3 | 3.30e-05 | 3 | 116 | 2 | 29320969 |
| Pubmed | Relationship between Axial Length and Levels of TGF-β in the Aqueous Humor and Plasma of Myopic Patients. | TGFB2 TGFB3 | 3.30e-05 | 3 | 116 | 2 | 33728344 |
| Pubmed | Aberrant TGFβ Signaling Contributes to Altered Trophoblast Differentiation in Preeclampsia. | TGFB2 TGFB3 | 3.30e-05 | 3 | 116 | 2 | 26653761 |
| Pubmed | In situ hybridization analysis of TGF beta 3 RNA expression during mouse development: comparative studies with TGF beta 1 and beta 2. | TGFB2 TGFB3 | 3.30e-05 | 3 | 116 | 2 | 1723948 |
| Pubmed | Localization and binding of transforming growth factor-beta isoforms in mouse preimplantation embryos and in delayed and activated blastocysts. | TGFB2 TGFB3 | 3.30e-05 | 3 | 116 | 2 | 1577201 |
| Pubmed | Transforming growth factor-beta. A family of growth regulatory peptides. | TGFB2 TGFB3 | 3.30e-05 | 3 | 116 | 2 | 2375595 |
| Pubmed | Orai3 and Orai1 mediate CRAC channel function and metabolic reprogramming in B cells. | ORAI1 ORAI3 | 3.30e-05 | 3 | 116 | 2 | 36803766 |
| Pubmed | Embryonic gene expression patterns of TGF beta 1, beta 2 and beta 3 suggest different developmental functions in vivo. | TGFB2 TGFB3 | 3.30e-05 | 3 | 116 | 2 | 1707784 |
| Pubmed | Developing human minor salivary glands: morphological parallel relation between the expression of TGF-beta isoforms and cytoskeletal markers of glandular maturation. | TGFB2 TGFB3 | 3.30e-05 | 3 | 116 | 2 | 18080134 |
| Pubmed | Circulating levels of transforming growth factor beta-1, 2 and 3 in HIV associated preeclamptic pregnancies. | TGFB2 TGFB3 | 3.30e-05 | 3 | 116 | 2 | 36006052 |
| Pubmed | Regulation of proliferation, motility, and contractivity of cultured human endometrial stromal cells by transforming growth factor-beta isoforms. | TGFB2 TGFB3 | 3.30e-05 | 3 | 116 | 2 | 16210002 |
| Pubmed | Soluble HLA-G and TGF-β in couples attending assisted reproduction - A possible role of TGF-β isoforms in semen? | TGFB2 TGFB3 | 3.30e-05 | 3 | 116 | 2 | 31837543 |
| Pubmed | Distinct pharmacological profiles of ORAI1, ORAI2, and ORAI3 channels. | ORAI1 ORAI3 | 3.30e-05 | 3 | 116 | 2 | 32896813 |
| Pubmed | TGF-beta isoforms in renal fibrogenesis. | TGFB2 TGFB3 | 3.30e-05 | 3 | 116 | 2 | 12911534 |
| Pubmed | TGF-β concentrations and activity are down-regulated in the aqueous humor of patients with neovascular age-related macular degeneration. | TGFB2 TGFB3 | 3.30e-05 | 3 | 116 | 2 | 29795291 |
| Pubmed | TGF-beta latency-associated peptides (LAPs) in human dentin matrix and pulp. | TGFB2 TGFB3 | 3.30e-05 | 3 | 116 | 2 | 12489185 |
| Pubmed | A calcium-redox feedback loop controls human monocyte immune responses: The role of ORAI Ca2+ channels. | ORAI1 ORAI3 | 3.30e-05 | 3 | 116 | 2 | 26956485 |
| Pubmed | Regulation of TGF beta 3 gene expression in embryonic palatal tissue. | TGFB2 TGFB3 | 3.30e-05 | 3 | 116 | 2 | 7842167 |
| Pubmed | Tgfbeta2 -/- Tgfbeta3 -/- double knockout mice display severe midline fusion defects and early embryonic lethality. | TGFB2 TGFB3 | 3.30e-05 | 3 | 116 | 2 | 12478370 |
| Pubmed | Developmental expression of the TGF beta s in the mouse cochlea. | TGFB2 TGFB3 | 3.30e-05 | 3 | 116 | 2 | 10349630 |
| Pubmed | Defective mast cell effector functions in mice lacking the CRACM1 pore subunit of store-operated calcium release-activated calcium channels. | ORAI1 ORAI3 | 3.30e-05 | 3 | 116 | 2 | 18059270 |
| Pubmed | Enhanced expression of transforming growth factor-beta isoforms in the neural tube of embryos derived from diabetic mice exposed to cyclophosphamide. | TGFB2 TGFB3 | 3.30e-05 | 3 | 116 | 2 | 14550911 |
| Pubmed | Chromosomal mapping of genes for transforming growth factors beta 2 and beta 3 in man and mouse: dispersion of TGF-beta gene family. | TGFB2 TGFB3 | 3.30e-05 | 3 | 116 | 2 | 3226728 |
| Pubmed | Co-expression of serotonin 5-HT(1B) and 5-HT(4) receptors in p11 containing cells in cerebral cortex, hippocampus, caudate-putamen and cerebellum. | HTR1B HTR4 | 3.30e-05 | 3 | 116 | 2 | 21300076 |
| Pubmed | The involvement of multifunctional TGF-β and related cytokines in pathogenesis of endometriosis. | TGFB2 TGFB3 | 3.30e-05 | 3 | 116 | 2 | 30367890 |
| Pubmed | Comparative effects of transforming growth factor beta isoforms on redox metabolism in thyroid cells. | TGFB2 TGFB3 | 3.30e-05 | 3 | 116 | 2 | 29061379 |
| Pubmed | Dynamic assembly of a membrane signaling complex enables selective activation of NFAT by Orai1. | ORAI1 ORAI3 | 3.30e-05 | 3 | 116 | 2 | 24909327 |
| Pubmed | Transforming growth factor-beta2 enhances differentiation of cardiac myocytes from embryonic stem cells. | TGFB2 TGFB3 | 3.30e-05 | 3 | 116 | 2 | 15896309 |
| Pubmed | TGF-β mediates proinflammatory seminal fluid signaling in human cervical epithelial cells. | TGFB2 TGFB3 | 3.30e-05 | 3 | 116 | 2 | 22706080 |
| Pubmed | Transforming growth factor (TGF)-β levels and unprovoked recurrent venous thromboembolism. | TGFB2 TGFB3 | 3.30e-05 | 3 | 116 | 2 | 24402195 |
| Pubmed | Glucocorticoids modulate TGF-beta production by human fetal lung fibroblasts. | TGFB2 TGFB3 | 3.30e-05 | 3 | 116 | 2 | 12772773 |
| Pubmed | Expression and function of transforming growth factor β in melioidosis. | TGFB2 TGFB3 | 3.30e-05 | 3 | 116 | 2 | 22331429 |
| Pubmed | A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function. | ORAI1 ORAI3 | 3.30e-05 | 3 | 116 | 2 | 16582901 |
| Pubmed | Quantitative analysis of transforming growth factor beta isoforms mRNA in the human corneal epithelium. | TGFB2 TGFB3 | 3.30e-05 | 3 | 116 | 2 | 18498721 |
| Pubmed | The TGF-beta2 isoform is both a required and sufficient inducer of murine hair follicle morphogenesis. | TGFB2 TGFB3 | 3.30e-05 | 3 | 116 | 2 | 10433821 |
| Pubmed | Cloning and developmental expression of the chick type II and type III TGF beta receptors. | TGFB2 TGFB3 | 3.30e-05 | 3 | 116 | 2 | 8167376 |
| Pubmed | Role of TGF-beta in RA-induced cleft palate in CD-1 mice. | TGFB2 TGFB3 | 3.30e-05 | 3 | 116 | 2 | 9839358 |
| Pubmed | The role of TGF-beta in mice infected with Heligmosomoides polygyrus. | TGFB2 TGFB3 | 3.30e-05 | 3 | 116 | 2 | 16879310 |
| Pubmed | Temporal and distinct TGFbeta ligand requirements during mouse and avian endocardial cushion morphogenesis. | TGFB2 TGFB3 | 3.30e-05 | 3 | 116 | 2 | 12142029 |
| Pubmed | Immunohistochemical localization of TGF beta 1, TGF beta 2, and TGF beta 3 in the mouse embryo: expression patterns suggest multiple roles during embryonic development. | TGFB2 TGFB3 | 3.30e-05 | 3 | 116 | 2 | 1955457 |
| Pubmed | Localization and actions of transforming growth factor-beta s in the embryonic nervous system. | TGFB2 TGFB3 | 3.30e-05 | 3 | 116 | 2 | 1764993 |
| Pubmed | Effects of transforming growth factor-β subtypes on in vitro cartilage production and mineralization of human bone marrow stromal-derived mesenchymal stem cells. | TGFB2 TGFB3 | 3.30e-05 | 3 | 116 | 2 | 21305699 |
| Pubmed | Constitutively high-level expression of TGFβ isoforms in cord blood and its relationship to perinatal findings. | TGFB2 TGFB3 | 3.30e-05 | 3 | 116 | 2 | 25743244 |
| Pubmed | Diverse Signaling by TGFβ Isoforms in Response to Focal Injury is Associated with Either Retinal Regeneration or Reactive Gliosis. | TGFB2 TGFB3 | 3.30e-05 | 3 | 116 | 2 | 32219603 |
| Pubmed | Expression of Orai genes and I(CRAC) activation in the human retinal pigment epithelium. | ORAI1 ORAI3 | 3.30e-05 | 3 | 116 | 2 | 20607548 |
| Pubmed | Opposite regulation of transforming growth factors-beta2 and -beta3 expression in the human endometrium. | TGFB2 TGFB3 | 3.30e-05 | 3 | 116 | 2 | 18039789 |
| Pubmed | Mechanisms for asporin function and regulation in articular cartilage. | TGFB2 TGFB3 | 6.59e-05 | 4 | 116 | 2 | 17827158 |
| Cytoband | Ensembl 112 genes in cytogenetic band chr11q12 | OR5D16 OR8J2 OR6Q1 OR9Q1 OR10Q1 OR8H1 OR5J2 OR5F1 | 2.95e-06 | 345 | 116 | 8 | chr11q12 |
| Cytoband | 9q31.1 | OR13C8 OR13C3 OR13C4 OR13C9 | 3.65e-06 | 41 | 116 | 4 | 9q31.1 |
| Cytoband | 11q12.1 | OR8J2 OR6Q1 OR9Q1 OR10Q1 OR8H1 OR5F1 | 3.66e-06 | 161 | 116 | 6 | 11q12.1 |
| Cytoband | Ensembl 112 genes in cytogenetic band chr11q24 | OR8D2 OR8B4 OR10D3 OR8B12 OR4D5 OR6T1 | 9.73e-06 | 191 | 116 | 6 | chr11q24 |
| Cytoband | 11q24.2 | OR8D2 OR8B4 OR10D3 OR8B12 | 2.05e-05 | 63 | 116 | 4 | 11q24.2 |
| Cytoband | 11p11.12 | OR4C45 OR4C46 OR4C13 | 1.68e-04 | 42 | 116 | 3 | 11p11.12 |
| Cytoband | 1q44 | OR2T29 OR2G3 OR2T5 OR14C36 | 1.82e-04 | 110 | 116 | 4 | 1q44 |
| Cytoband | 1q23.1 | OR10Z1 OR6N1 OR10K1 | 2.20e-04 | 46 | 116 | 3 | 1q23.1 |
| Cytoband | 11q11 | OR5D16 OR4C6 OR5J2 | 2.35e-04 | 47 | 116 | 3 | 11q11 |
| Cytoband | Ensembl 112 genes in cytogenetic band chr1q44 | OR2T29 OR2G3 OR2T5 OR14C36 | 3.24e-04 | 128 | 116 | 4 | chr1q44 |
| Cytoband | Ensembl 112 genes in cytogenetic band chr9q31 | OR13C8 OR13C3 OR13C4 OR13C9 | 4.19e-04 | 137 | 116 | 4 | chr9q31 |
| Cytoband | 16q22.2 | CMTR2 PHLPP2 | 1.41e-03 | 22 | 116 | 2 | 16q22.2 |
| Cytoband | 11q24.1 | OR4D5 OR6T1 | 3.98e-03 | 37 | 116 | 2 | 11q24.1 |
| Cytoband | Ensembl 112 genes in cytogenetic band chr11q11 | OR4C6 OR4C46 | 4.64e-03 | 40 | 116 | 2 | chr11q11 |
| GeneFamily | Olfactory receptors, family 4 | OR4C6 OR4E1 OR4C45 OR4C46 OR4C13 OR4F21 OR4D5 OR4X1 OR4K3 | 3.33e-08 | 129 | 98 | 9 | 151 |
| GeneFamily | Olfactory receptors, family 13 | OR13C8 OR13C3 OR13C4 OR13C9 | 6.64e-06 | 23 | 98 | 4 | 162 |
| GeneFamily | Olfactory receptors, family 8 | OR8J2 OR8D2 OR8B4 OR8H1 OR8B12 | 6.66e-06 | 49 | 98 | 5 | 155 |
| GeneFamily | Olfactory receptors, family 6 | OR6Q1 OR6N1 OR6A2 OR6T1 OR6B2 | 8.14e-06 | 51 | 98 | 5 | 153 |
| GeneFamily | Olfactory receptors, family 10 | OR10P1 OR10Q1 OR10Z1 OR10D3 OR10K1 | 2.90e-05 | 66 | 98 | 5 | 157 |
| GeneFamily | ORAI calcium release-activated calcium modulators | ORAI1 ORAI3 | 8.69e-05 | 3 | 98 | 2 | 668 |
| GeneFamily | Olfactory receptors, family 14 | OR14J1 OR14C36 | 6.00e-04 | 7 | 98 | 2 | 163 |
| GeneFamily | 5-hydroxytryptamine receptors, G protein-coupled | HTR1B HTR4 | 2.18e-03 | 13 | 98 | 2 | 170 |
| GeneFamily | CD molecules|Mucins | MUC3B MUC6 | 5.71e-03 | 21 | 98 | 2 | 648 |
| Coexpression | GSE8835_CD4_VS_CD8_TCELL_CLL_PATIENT_DN | ADGRG5 GALNT3 CTC1 TRRAP PCGF6 SAMD10 DIP2C | 9.10e-06 | 200 | 96 | 7 | M6258 |
| Disease | Congenital abnormality of respiratory system | TGFB2 TGFB3 | 3.40e-05 | 3 | 100 | 2 | C0035238 |
| Disease | obesity (implicated_via_orthology) | GPR12 DHX33 MED13L THADA TLR4 MED13 | 9.41e-05 | 215 | 100 | 6 | DOID:9970 (implicated_via_orthology) |
| Disease | Loeys-Dietz Aortic Aneurysm Syndrome | TGFB2 TGFB3 | 1.13e-04 | 5 | 100 | 2 | C1836635 |
| Disease | Loeys-Dietz Syndrome, Type 1a | TGFB2 TGFB3 | 1.13e-04 | 5 | 100 | 2 | C4551955 |
| Disease | Loeys-Dietz Syndrome | TGFB2 TGFB3 | 2.36e-04 | 7 | 100 | 2 | C2697932 |
| Disease | middle temporal gyrus volume measurement | OR13C3 OR13C4 | 6.13e-04 | 11 | 100 | 2 | EFO_0010316 |
| Disease | Pulmonary Emphysema | TGFB2 TGFB3 | 1.50e-03 | 17 | 100 | 2 | C0034067 |
| Disease | diabetic neuropathy (biomarker_via_orthology) | TGFB2 TGFB3 | 1.50e-03 | 17 | 100 | 2 | DOID:9743 (biomarker_via_orthology) |
| Disease | bone density | TRABD2B GALNT3 MED13L MINDY4 ESPL1 ATPAF2 | 2.10e-03 | 388 | 100 | 6 | EFO_0003923 |
| Disease | haptoglobin measurement | CMTR2 PHLPP2 | 2.29e-03 | 21 | 100 | 2 | EFO_0004640 |
| Disease | carotid artery disease (is_implicated_in) | TLR4 GNB3 | 2.51e-03 | 22 | 100 | 2 | DOID:3407 (is_implicated_in) |
| Disease | Cleft Palate | MED13L TGFB2 TGFB3 | 2.66e-03 | 81 | 100 | 3 | C0008925 |
