Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

KNTC1 CACNA1C MYH1 PPAN SLCO2B1 RAB8B SKIDA1 TEX14 RAB8A RAB10 LMOD3 DST KIAA0825 SACS PIP4K2A DMD ABCC2 ATP1A4 MNDA AP3D1

9.10e-0914421042035575683
Pubmed

Rab8a and Rab8b are essential for several apical transport pathways but insufficient for ciliogenesis.

RAB8B RAB8A RAB10

1.04e-074104324213529
Pubmed

Blood-induced bone loss in murine hemophilic arthropathy is prevented by blocking the iRhom2/ADAM17/TNF-α pathway.

FRMD8 F8 FRMD8P1

5.16e-076104329776906
Pubmed

GRAF2, WDR44, and MICAL1 mediate Rab8/10/11-dependent export of E-cadherin, MMP14, and CFTR ΔF508.

RAB8B RAB8A RAB10

2.15e-069104332344433
Pubmed

EHBP1L1 coordinates Rab8 and Bin1 to regulate apical-directed transport in polarized epithelial cells.

RAB8B RAB8A RAB10

7.27e-0613104326833786
Pubmed

AT1-receptor response to non-saturating Ang-II concentrations is amplified by calcium channel blockers.

CACNA1C AGTR1

8.86e-062104228514967
Pubmed

Immunohistochemical Assessment of the Expression of Biliary Transportation Proteins MRP2 and MRP3 in Hepatocellular Carcinoma and in Cholangiocarcinoma.

ABCC3 ABCC2

8.86e-062104229464551
Pubmed

Dose-dependent disposition of methotrexate in Abcc2 and Abcc3 gene knockout murine models.

ABCC3 ABCC2

8.86e-062104221841039
Pubmed

Expression microarray analysis reveals alternative splicing of LAMA3 and DST genes in head and neck squamous cell carcinoma.

LAMA3 DST

8.86e-062104224675808
Pubmed

Differential modulation of the human liver conjugate transporters MRP2 and MRP3 by bile acids and organic anions.

ABCC3 ABCC2

8.86e-062104212704183
Pubmed

Altered regulation of hepatic efflux transporters disrupts acetaminophen disposition in pediatric nonalcoholic steatohepatitis.

ABCC3 ABCC2

8.86e-062104225788542
Pubmed

Expression of the multidrug resistance proteins MRP2 and MRP3 in human hepatocellular carcinoma.

ABCC3 ABCC2

8.86e-062104211745434
Pubmed

Major glucuronide metabolites of testosterone are primarily transported by MRP2 and MRP3 in human liver, intestine and kidney.

ABCC3 ABCC2

8.86e-062104230959153
Pubmed

Impact of Abcc2 (Mrp2) and Abcc3 (Mrp3) on the in vivo elimination of methotrexate and its main toxic metabolite 7-hydroxymethotrexate.

ABCC3 ABCC2

8.86e-062104219088030
Pubmed

Blood-Brain Barrier: From Physiology to Disease and Back.

ABCC3 SLCO2B1 DMD ABCC2 ATP1A4

1.65e-05105104530280653
Pubmed

EHBP1L1, an apicobasal polarity regulator, is critical for nuclear polarization during enucleation of erythroblasts.

RAB8B RAB8A RAB10

1.71e-0517104337042948
Pubmed

The LRRK2 kinase substrates RAB8a and RAB10 contribute complementary but distinct disease-relevant phenotypes in human neurons.

RAB8A RAB10

2.65e-053104238307024
Pubmed

The role of multidrug resistance proteins MRP1, MRP2 and MRP3 in cellular folate homeostasis.

ABCC3 ABCC2

2.65e-053104212628490
Pubmed

Increased multidrug resistance-associated protein activity in mononuclear cells of patients with systemic lupus erythematosus.

ABCC3 ABCC2

2.65e-053104218799096
Pubmed

Physiological and pharmacological functions of Mrp2, Mrp3 and Mrp4 as determined from recent studies on gene-disrupted mice.

ABCC3 ABCC2

2.65e-053104217273943
Pubmed

FRMD8 targets both CDK4 activation and RB degradation to suppress colon cancer growth.

FRMD8 FRMD8P1

2.65e-053104237527040
Pubmed

Vectorial transport of fexofenadine across Caco-2 cells: involvement of apical uptake and basolateral efflux transporters.

ABCC3 SLCO2B1

2.65e-053104221780830
Pubmed

Involvement of multiple efflux transporters in hepatic disposition of fexofenadine.

ABCC3 ABCC2

2.65e-053104218245269
Pubmed

Hepatocellular Shuttling and Recirculation of Sorafenib-Glucuronide Is Dependent on Abcc2, Abcc3, and Oatp1a/1b.

ABCC3 ABCC2

2.65e-053104225952649
Pubmed

Complex pharmacokinetic behavior of ezetimibe depends on abcc2, abcc3, and abcg2.

ABCC3 ABCC2

2.65e-053104219443695
Pubmed

Application of multivariate statistical procedures to identify transcription factors that correlate with MRP2, 3, and 4 mRNA in adult human livers.

ABCC3 ABCC2

2.65e-053104219480556
Pubmed

Abcc2 (Mrp2), Abcc3 (Mrp3), and Abcg2 (Bcrp1) are the main determinants for rapid elimination of methotrexate and its toxic metabolite 7-hydroxymethotrexate in vivo.

ABCC3 ABCC2

2.65e-053104219996279
Pubmed

A Rab8-specific GDP/GTP exchange factor is involved in actin remodeling and polarized membrane transport.

RAB8B RAB8A

2.65e-053104212221131
Pubmed

Mutational analysis of a highly conserved proline residue in MRP1, MRP2, and MRP3 reveals a partially conserved function.

ABCC3 ABCC2

2.65e-053104217494643
Pubmed

The ADAM17 sheddase complex regulator iTAP/Frmd8 modulates inflammation and tumor growth.

FRMD8 FRMD8P1

2.65e-053104236720499
Pubmed

Toll-like receptor 3 is required for development of retinopathy caused by impaired all-trans-retinal clearance in mice.

ABCA4 TLR3

2.65e-053104221383019
Pubmed

EFR3s are palmitoylated plasma membrane proteins that control responsiveness to G-protein-coupled receptors.

EFR3A AGTR1

2.65e-053104225380825
Pubmed

Chloroquine-Inducible Par-4 Secretion Is Essential for Tumor Cell Apoptosis and Inhibition of Metastasis.

RAB8B RAB8A

2.65e-053104228076793
Pubmed

Rab8 GTPase regulates Klotho-mediated inhibition of cell growth and progression by directly modulating its surface expression in human non-small cell lung cancer.

RAB8B RAB8A

2.65e-053104231707148
Pubmed

Influence of serum in hemodialysis patients on the expression of intestinal and hepatic transporters for the excretion of pravastatin.

SLCO2B1 ABCC2

2.65e-053104223190519
Pubmed

Tex19.1 promotes Spo11-dependent meiotic recombination in mouse spermatocytes.

UBR2 SPO11

2.65e-053104228708824
Pubmed

Multidrug resistance proteins 2 and 3 provide alternative routes for hepatic excretion of morphine-glucuronides.

ABCC3 ABCC2

2.65e-053104217485564
Pubmed

Expression of AT1R, AT2R and AT4R and their roles in extravillous trophoblast invasion in the human.

LNPEP AGTR1

2.65e-053104220304486
Pubmed

Characterization of the human ABC superfamily: isolation and mapping of 21 new genes using the expressed sequence tags database.

ABCC3 ABCA4 ABCC2

3.84e-052210438894702
Pubmed

Pharmacokinetic and Pharmacodynamic Investigations of ION-353382, a Model Antisense Oligonucleotide: Using Alpha-2-Macroglobulin and Murinoglobulin Double-Knockout Mice.

A2M SCARB1

5.29e-054104227031383
Pubmed

Phosphoproteomic screening identifies Rab GTPases as novel downstream targets of PINK1.

RAB8B RAB8A

5.29e-054104226471730
Pubmed

High plasma pravastatin concentrations are associated with single nucleotide polymorphisms and haplotypes of organic anion transporting polypeptide-C (OATP-C, SLCO1B1).

SLCO2B1 ABCC2

5.29e-054104215226675
Pubmed

RAB8, RAB10 and RILPL1 contribute to both LRRK2 kinase-mediated centrosomal cohesion and ciliogenesis deficits.

RAB8A RAB10

5.29e-054104231428781
Pubmed

Expression analysis of genes encoding TEX11, TEX12, TEX14 and TEX15 in testis tissues of men with non-obstructive azoospermia.

TEX14 TEX12

5.29e-054104229932616
Pubmed

Regulation of mRNA expression of MDR1, MRP1, MRP2 and MRP3 by prototypical microsomal enzyme inducers in primary cultures of human and rat hepatocytes.

ABCC3 ABCC2

5.29e-054104216946557
Pubmed

Angiotensin II Triggers Peripheral Macrophage-to-Sensory Neuron Redox Crosstalk to Elicit Pain.

AGTR1 TRPV4

5.29e-054104229976627
Pubmed

The Organic Anion-Transporting Peptide 2B1 Is Localized in the Basolateral Membrane of the Human Jejunum and Caco-2 Monolayers.

ABCC3 ABCC2

5.29e-054104228408210
Pubmed

Nrf2-dependent and -independent induction of ABC transporters ABCC1, ABCC2, and ABCG2 in HepG2 cells under oxidative stress.

ABCC3 ABCC2

5.29e-054104218038766
Pubmed

Polymorphisms of the drug transporters ABCB1, ABCG2, ABCC2 and ABCC3 and their impact on drug bioavailability and clinical relevance.

ABCC3 ABCC2

5.29e-054104225162314
Pubmed

Absence of SHIP-1 results in constitutive phosphorylation of tank-binding kinase 1 and enhanced TLR3-dependent IFN-beta production.

INPP5D TLR3

5.29e-054104220100929
Pubmed

Myomerger induces fusion of non-fusogenic cells and is required for skeletal muscle development.

MYH1 DMD

5.29e-054104228569755
Pubmed

Influence of SLCO1B1, 1B3, 2B1 and ABCC2 genetic polymorphisms on mycophenolic acid pharmacokinetics in Japanese renal transplant recipients.

SLCO2B1 ABCC2

5.29e-054104217906856
Pubmed

Chaperone-assisted production of active human Rab8A GTPase in Escherichia coli.

RAB8A RAB10

5.29e-054104219116169
Pubmed

Cloning and characterization of mouse ACF7, a novel member of the dystonin subfamily of actin binding proteins.

DST DMD

5.29e-05410428954775
Pubmed

Inhibition of tetramethylpyrazine on P-gp, MRP2, MRP3 and MRP5 in multidrug resistant human hepatocellular carcinoma cells.

ABCC3 ABCC2

5.29e-054104219956884
Pubmed

A pathway for Parkinson's Disease LRRK2 kinase to block primary cilia and Sonic hedgehog signaling in the brain.

RAB8A RAB10

5.29e-054104230398148
Pubmed

Integrated genome-wide association, coexpression network, and expression single nucleotide polymorphism analysis identifies novel pathway in allergic rhinitis.

LAMA3 DYRK4 FAM20C

5.69e-0525104325085501
Pubmed

FRMD8 promotes inflammatory and growth factor signalling by stabilising the iRhom/ADAM17 sheddase complex.

FRMD8 FRMD8P1

8.80e-055104229897336
Pubmed

iTAP, a novel iRhom interactor, controls TNF secretion by policing the stability of iRhom/TACE.

FRMD8 FRMD8P1

8.80e-055104229897333
Pubmed

Structural Basis for Rab8a Recruitment of RILPL2 via LRRK2 Phosphorylation of Switch 2.

RAB8A RAB10

8.80e-055104232017888
Pubmed

Molecular and genetic mapping of the mouse mdx locus.

F8 DMD

8.80e-05510423243547
Pubmed

A meta-analysis of genome-wide association studies identifies novel variants associated with osteoarthritis of the hip.

DNAH10 IFRD1

8.80e-055104223989986
Pubmed

The interaction of JRAB/MICAL-L2 with Rab8 and Rab13 coordinates the assembly of tight junctions and adherens junctions.

RAB8B RAB8A

8.80e-055104218094055
Pubmed

AS160, the Akt substrate regulating GLUT4 translocation, has a functional Rab GTPase-activating protein domain.

RAB8A RAB10

8.80e-055104215971998
Pubmed

Ochratoxin A transport by the human breast cancer resistance protein (BCRP), multidrug resistance protein 2 (MRP2), and organic anion-transporting polypeptides 1A2, 1B1 and 2B1.

SLCO2B1 ABCC2

8.80e-055104228532671
Pubmed

Complete OATP1B1 and OATP1B3 deficiency causes human Rotor syndrome by interrupting conjugated bilirubin reuptake into the liver.

ABCC3 ABCC2

1.32e-046104222232210
Pubmed

Reduced levels of dystrophin associated proteins in the brains of mice deficient for Dp71.

F8 DMD

1.32e-04610428872469
Pubmed

Sequence of the human factor VIII-associated gene is conserved in mouse.

F8 DMD

1.32e-04610421639415
Pubmed

Annotation of loci from genome-wide association studies using tissue-specific quantitative interaction proteomics.

CACNA1C DMD

1.32e-046104224952909
Pubmed

Expressions of hepatobiliary organic anion transporters and bilirubin-conjugating enzyme in differentiating embryonic stem cells.

ABCC3 ABCC2

1.32e-046104212951053
Pubmed

Comparison of the physical and recombination maps of the mouse X chromosome.

F8 DMD

1.84e-04710422571569
Pubmed

Three novel collagen VI chains with high homology to the alpha3 chain.

LAMA3 COL6A5

1.84e-047104218276594
Pubmed

Sequence characteristics, subcellular localization, and substrate specificity of DYRK-related kinases, a novel family of dual specificity protein kinases.

DYRK4 DYRK2

1.84e-04710429748265
Pubmed

Association of multi-drug resistance gene polymorphisms with pancreatic cancer outcome.

ABCC3 ABCC2

1.84e-047104220922799
Pubmed

Localization of monoamine oxidase A and B genes on the mouse X chromosome.

F8 DMD

1.84e-04710422573045
Pubmed

Family-wide characterization of the DENN domain Rab GDP-GTP exchange factors.

RAB8B RAB8A RAB10

1.87e-0437104320937701
Pubmed

Requirement of the Mowat-Wilson Syndrome Gene Zeb2 in the Differentiation and Maintenance of Non-photoreceptor Cell Types During Retinal Development.

ABCA4 PDE6C BHLHE22

2.20e-0439104329922981
Pubmed

Localization of the mdx mutation within the mouse dystrophin gene.

F8 DMD

2.45e-04810422903046
Pubmed

Cloning of Rab GTPases expressed in human skeletal muscle: studies in insulin-resistant subjects.

RAB8A RAB10

2.45e-04810429918381
Pubmed

Systematic proteomic analysis of LRRK2-mediated Rab GTPase phosphorylation establishes a connection to ciliogenesis.

RAB8A RAB10

2.45e-048104229125462
Pubmed

Tissue distribution and hepatic and renal ontogeny of the multidrug resistance-associated protein (Mrp) family in mice.

ABCC3 ABCC2

2.45e-048104215802388
Pubmed

Long noncoding RNA lncMREF promotes myogenic differentiation and muscle regeneration by interacting with the Smarca5/p300 complex.

MYH1 DMD

2.45e-048104236200826
Pubmed

Kelch Domain of Gigaxonin Interacts with Intermediate Filament Proteins Affected in Giant Axonal Neuropathy.

DNAH10 RNF213 ZZEF1 DST DMD

2.55e-04187104526460568
Pubmed

Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

ARFGEF3 NWD2 SERINC1 PLXNB3

2.66e-04103104410574462
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

UBR2 CAD RNGTT CDC42BPA RNF213 EFR3A FANCD2 RAB10 LNPEP CSTF3 DMD

3.09e-0410491041127880917
Pubmed

Analysis of the interactions between BP180, BP230, plectin and the integrin alpha6beta4 important for hemidesmosome assembly.

LAMA3 DST

3.14e-049104212482924
Pubmed

Structure, chromosomal location, and expression pattern of three mouse genes homologous to the human MAGE genes.

F8 DMD

3.14e-04910427590750
Pubmed

LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.

KNTC1 CAD CDC42BPA CKAP5 AP3D1

3.63e-04202104533005030
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

MYH1 RNGTT CKAP5 RNF213 ZZEF1 FAM20C DST TLR3 PLXNB3

3.73e-04736104929676528
Pubmed

Comparative mapping on the mouse and human X chromosomes of a human cDNA clone encoding the vasopressin renal-type receptor (AVP2R).

F8 DMD

3.92e-041010428449515
Pubmed

Linkage of a gene for neural cell adhesion molecule, L1 (CamL1) to the Rsvp region of the mouse X chromosome.

F8 DMD

3.92e-041010421964443
Pubmed

Physical mapping of the loci Gabra3, DXPas8, CamL1, and Rsvp in a region of the mouse X chromosome homologous to human Xq28.

F8 DMD

3.92e-041010421684949
Pubmed

Identification of DeltaNp63alpha protein interactions by mass spectrometry.

A2M CAD SACS

4.07e-0448104320085233
Pubmed

Physical linkage of the A-raf-1, properdin, synapsin I, and TIMP genes on the human and mouse X chromosomes.

F8 DMD

4.79e-041110421572636
Pubmed

Beta4 integrin is required for hemidesmosome formation, cell adhesion and cell survival.

LAMA3 DST

4.79e-041110428707838
Pubmed

The tetraspan molecule CD151, a novel constituent of hemidesmosomes, associates with the integrin alpha6beta4 and may regulate the spatial organization of hemidesmosomes.

LAMA3 DST

4.79e-0411104210811835
Pubmed

Current insights into the formation and breakdown of hemidesmosomes.

LAMA3 DST

4.79e-0411104216757171
Pubmed

Interactions of the Antiviral Factor Interferon Gamma-Inducible Protein 16 (IFI16) Mediate Immune Signaling and Herpes Simplex Virus-1 Immunosuppression.

PPAN WDR36 CKAP5 RNF213 STK3 PIP4K2A

5.01e-04332104625693804
Pubmed

Establishment and Dysfunction of the Blood-Brain Barrier.

ABCC3 SLCO2B1 ABCC2

5.16e-0452104326590417
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

CAD PPAN WDR36 RNGTT CDC42BPA CKAP5 API5 EFR3A RAB10 IFRD1 DST LNPEP CSTF3

5.30e-0414971041331527615
Cytoband1q42.11

CDC42BPA DEGS1

2.26e-041010421q42.11
GeneFamilyATP binding cassette subfamily C

ABCC3 ABCC2

8.53e-0413612807
GeneFamilyRAB, member RAS oncogene GTPases

RAB8B RAB8A RAB10

1.38e-0365613388
GeneFamilyZinc fingers ZZ-type|Lysine acetyltransferases

ZZEF1 DMD

1.65e-031861291
CoexpressionCUI_TCF21_TARGETS_2_DN

IL13RA1 DEGS1 STK3 ARFGEF3 IFRD1 DST SERINC1 LNPEP AGTR1 TLR3 RIMOC1 CD47 MNDA SH3BP5

9.94e-0688810314MM1018
CoexpressionCOATES_MACROPHAGE_M1_VS_M2_UP

SLCO2B1 LAMA3 ARFGEF3 RAB10 DST

2.43e-05871035M13671
CoexpressionCUI_TCF21_TARGETS_2_DN

IL13RA1 DEGS1 STK3 ARFGEF3 IFRD1 DST SERINC1 LNPEP AGTR1 TLR3 RIMOC1 CD47 SH3BP5

3.05e-0585410313M1533
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

UBR2 RNGTT CDC42BPA CKAP5 ZZEF1 EFR3A STK3 IFRD1 DST SACS PIP4K2A DMD ZBTB18

3.12e-0585610313M4500
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

A2M MYH1 ABCA4 DNAH10 ARFGEF3 GUCY2F DMD ATP1A4

1.15e-0818410382cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

A2M MYH1 ABCA4 DNAH10 ARFGEF3 GUCY2F DMD ATP1A4

1.15e-081841038ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

A2M MYH1 ABCA4 DNAH10 ARFGEF3 GUCY2F DMD ATP1A4

1.15e-0818410382b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellBAL-Control-Myeloid-Macrophage|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

A2M HTRA4 FAM20C KCNF1 SCARB1 ATP1A4

4.30e-0618310368e9d45c96b44558158e3d59613f64a73d5390c19
ToppCellBAL-Control-Myeloid-Macrophage-transitional_Macro-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

A2M HTRA4 FAM20C KCNF1 SCARB1 ATP1A4

4.30e-0618310360408d991ddb639594b45d5cb2432dd29289167b1
ToppCellBAL-Control-Myeloid-Macrophage-transitional_Macro|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

A2M HTRA4 FAM20C KCNF1 SCARB1 ATP1A4

4.30e-06183103679f05b8a967124d831b0baef137e30659f5917a7
ToppCellBAL-Control-Myeloid-Macrophage-transitional_Macro-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

A2M HTRA4 FAM20C KCNF1 SCARB1 ATP1A4

4.44e-06184103692202e1cd0bba1ce4b061ebcb8a2af5bb590542a
ToppCellBAL-Control-Myeloid-Macrophage|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

A2M HTRA4 FAM20C KCNF1 SCARB1 ATP1A4

4.44e-0618410367331535d469453a5264dcb0270a97f63d3b55201
ToppCellBAL-Control-Myeloid-Macrophage-transitional_Macro|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

A2M HTRA4 FAM20C KCNF1 SCARB1 ATP1A4

4.44e-061841036337e38a6b2b6770cc992d88b006829f194841b10
ToppCellCD8+_Memory_T_cell-CV-7|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

A2M KNTC1 UBR2 WDR36 RNF213 LNPEP

5.50e-0619110369454f642c3621370fa23640b631301346b300950
ToppCellIPF-Epithelial-Ciliated|Epithelial / Disease state, Lineage and Cell class

DNAH10 FHAD1 CFAP54 KIAA0825 VWA3B DMD

5.83e-061931036ad58f5080e0ba65c845056ea6b79037b636e9c64
ToppCellNon-neuronal-Postmitotic-Microglia-Microglia-8|World / Primary Cells by Cluster

A2M IL13RA1 TMEM144 SLCO2B1 INPP5D MNDA

6.56e-06197103693bce9741dec4e60dd470acca87cd4c8074f8876
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH10 FHAD1 CFAP54 KIAA0825 VWA3B DMD

6.56e-06197103674a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW16-Myeloid-Microglia|GW16 / Sample Type, Dataset, Time_group, and Cell type.

A2M IL13RA1 TMEM144 SLCO2B1 INPP5D MNDA

6.75e-061981036901cd39cb84f1907f2f5d27221979c854bd3b40e
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW16-Myeloid|GW16 / Sample Type, Dataset, Time_group, and Cell type.

A2M IL13RA1 TMEM144 SLCO2B1 INPP5D MNDA

6.75e-061981036cc292aa8518d5ef8940e2327f2f07d584a996d90
ToppCellParenchymal-NucSeq-Immune_Myeloid-Macrophage_other-Macro_CHIT1|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SLCO2B1 DYRK4 HTRA4 FAM20C SCARB1 MNDA

6.75e-0619810366a4161680b46b2c12353a693c403b5a4bb3da03f
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CHL1 ABCC3 LAMA3 DST LNPEP CD47

7.15e-062001036741e59c68ae4a3a7be830e98771a14f920c9e883
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CHL1 ABCC3 LAMA3 DST LNPEP CD47

7.15e-06200103655b7b17f2d413b9ebb262ef8bd210ef45618a7f3
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDC42BPA FRMD8 DEGS1 RAB10 SERINC1 PLXNB3

7.15e-062001036f0c338877e39226a90c4effe12f6501d33542a73
ToppCellSmart-seq2-tissue-resident_(Smart-seq2)-myeloid-myeloid_macrophage-microglial_cell|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

A2M IL13RA1 SLCO2B1 DST TLR3

3.23e-051571035d4908cafd8870c1c225817f589ea2bce116ac7ab
ToppCellfacs-Lung-nan-3m-Endothelial-Capillary_Type_1_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHL1 MYH1 TMEM144 DNAH10 PLXNB3

3.53e-051601035f2cdee5a9e3b0eb125d6be7b5d239eb04333ae41
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CACNA1C DNAH10 NWD2 GUCY2F ABCC2

3.75e-051621035bf886e22ff2a20353499004b53f25fb9e6574896
ToppCell390C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)|390C / Donor, Lineage, Cell class and subclass (all cells)

ABCC3 SLCO2B1 FHAD1 TRPV4 MNDA

4.58e-0516910352c851b2703c7b8b656026f996f5fc027e4a79b36
ToppCell5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH10 FHAD1 CFAP54 KIAA0825 VWA3B

4.58e-051691035fba841664939c771881ba97f14ef1df6635c04ff
ToppCellPND07-28-samps-Myeloid-Macrophage-CD163+_Macrophage|PND07-28-samps / Age Group, Lineage, Cell class and subclass

ABCC3 SLCO2B1 INPP5D TRPV4 MNDA

4.98e-0517210359a659442dc41bd2a4361a7e38a7ee37a39781667
ToppCell10x5'-bone_marrow-Myeloid_Mac-Intestinal_macrophages|bone_marrow / Manually curated celltypes from each tissue

A2M SLCO2B1 STK3 FAM20C DST

5.26e-0517410350746344d62aa7ab77c378e9d5a9f9238e741a76b
ToppCellfacs-Trachea-24m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l6-17|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CACNA1C MYH1 DNAH10 FHAD1 SLC35F3

5.71e-0517710358abdf1d970b2f15e17e185f3e612dd5065c88757
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-DC-DC3-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

IL13RA1 RAB8B RAB10 CCR7 ATP1A4

5.71e-051771035d34b086a5931d7f1737a504952d51c47693e91a8
ToppCell10x5'-lymph-node_spleen-Myeloid_Mac-Intestinal_macrophages|lymph-node_spleen / Manually curated celltypes from each tissue

A2M ABCC3 SLCO2B1 FAM20C DST

6.18e-0518010357be7d7a6906fff6dbdecd9cb013d855aba4eda2a
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_aging_sig-A|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

A2M IL13RA1 SLCO2B1 INPP5D MNDA

6.51e-051821035c6b3762ccec326f057819f75fa7fac0145fb7d54
ToppCellBAL-Severe-Myeloid-Macrophage|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

A2M IL13RA1 SLCO2B1 DST SCARB1

7.04e-051851035ae966929fb5bbb08ffcbac76cb21941638727f55
ToppCellBAL-Severe-Myeloid-Macrophage-transitional_Macro-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

A2M IL13RA1 SLCO2B1 DST SCARB1

7.04e-0518510353beebaa92275086b1fae5f8c0c3d54016c5ba2aa
ToppCellBAL-Severe-Myeloid-Macrophage-transitional_Macro-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

A2M IL13RA1 SLCO2B1 DST SCARB1

7.04e-051851035ceff11cfa679147ccfd0a0f8079e697a6bea34d9
ToppCellCV-Moderate-7|Moderate / Virus stimulation, Condition and Cluster

A2M KNTC1 UBR2 WDR36 RNF213

7.04e-051851035a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
ToppCellBAL-Severe-Myeloid-Macrophage|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

A2M IL13RA1 SLCO2B1 DST SCARB1

7.04e-0518510359aea5ed8f9cee5ee933891203aac7adb85d68201
ToppCellBAL-Severe-Myeloid-Macrophage-transitional_Macro|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

A2M IL13RA1 SLCO2B1 DST SCARB1

7.04e-05185103542939b294ea3e871274d8b73124c850dc1904fd2
ToppCellSevere_COVID-19-Myeloid-transitional_Macro|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）

A2M IL13RA1 SLCO2B1 DST SCARB1

7.04e-051851035f7ef0d7740b4cfedc38846e802898c402dc411fd
ToppCellBAL-Severe-Myeloid-Macrophage-transitional_Macro|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

A2M IL13RA1 SLCO2B1 DST SCARB1

7.04e-0518510357a3612520ae4f0cd61480eadba31eecce001419d
ToppCellCV-Moderate-7|CV / Virus stimulation, Condition and Cluster

A2M KNTC1 UBR2 WDR36 RNF213

7.22e-0518610358571956890fc9894d766ba294a28e376b4aba428
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_0|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

A2M IL13RA1 DST CCR7 ATP1A4

7.59e-0518810359fc3819aae5a2b2534cb131d467435b5cfc420d6
ToppCellfacs-Brain_Myeloid-Striatum-3m-Myeloid-nan|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC3 SLCO2B1 INPP5D SERINC1 PIP4K2A

7.78e-0518910356dd4ec5ce4beb856f0d2d1654e3c4676d1d63736
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CHL1 ABCC3 RNF213 DST LNPEP

7.78e-051891035aadb7a2de4cbe7f0958651f2739bba430b93f5c1
ToppCellfacs-Brain_Myeloid-Striatum-3m-Myeloid|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC3 SLCO2B1 INPP5D SERINC1 PIP4K2A

7.78e-0518910353ae479ec7e00c57127cbe51a398329b10ca9848c
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CHL1 ABCC3 RNF213 DST LNPEP

7.78e-0518910358977f3295b7df7c7474b3f371de90a82ae4bb50c
ToppCellfacs-Brain_Myeloid-Striatum-3m-Myeloid-microglial_cell|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC3 SLCO2B1 INPP5D SERINC1 PIP4K2A

7.78e-051891035875df61ee48baa5142ba4d2427bdec1c53e5a828
ToppCellCOPD-Epithelial-Ciliated|Epithelial / Disease state, Lineage and Cell class

DNAH10 FHAD1 CFAP54 KIAA0825 VWA3B

7.78e-0518910353e77883db34722b9ce0a03ea74caefc92dc7feff
ToppCellfacs-Brain_Myeloid-Striatum-3m|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC3 SLCO2B1 INPP5D SERINC1 PIP4K2A

7.78e-05189103597ef5215d841ff366a3e3682cd9bd04100cbfde0
ToppCellMonocytes-Tissue-resident_macrophages|World / Immune cells in Kidney/Urine in Lupus Nephritis

A2M IL13RA1 SLCO2B1 DST MNDA

7.98e-05190103507215e8f292cb54c670037aaf28393cddbe5548c
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Endothelial_Myeloid|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

A2M IL13RA1 SLCO2B1 INPP5D MNDA

7.98e-051901035d4f954e0748898df69e1710df558564db703dd61
ToppCellControl-Myeloid-transitional_Macro|Control / Disease group,lineage and cell class （2021.01.30）

A2M HTRA4 FAM20C SCARB1 ATP1A4

8.18e-0519110353ed0b1ff628a165e3c92c2e493206015f57dccfe
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-AC-like-AC-like_Prolif-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

KNTC1 CDC42BPA HEATR4 FANCD2 KIAA0825

8.38e-051921035d6f656be2698bd215717d35f4e7ab727c08c61e0
ToppCellfacs-Aorta-Heart-3m|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UBR2 LAMA3 F8 PIP4K2A GHITM

8.38e-0519210351ccc47792edf9ee23501c8e2165d11271636b66a
ToppCellMonocytes-Tissue-resident_macrophages|Monocytes / Immune cells in Kidney/Urine in Lupus Nephritis

A2M IL13RA1 SLCO2B1 DST TLR3

8.59e-051931035198552810dcac8d0ca63a78badd6702b49ff6edf
ToppCellControl-Epithelial-Ciliated|Epithelial / Disease state, Lineage and Cell class

DNAH10 FHAD1 CFAP54 KIAA0825 VWA3B

8.59e-0519310350e37d454f3735edd936ee9a5f5f516ac3aad400e
ToppCellfacs-Brain_Myeloid-Hippocampus-3m-Myeloid-microglial_cell|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLCO2B1 INPP5D DST PIP4K2A TLR3

8.59e-0519310359c16032bc03df8760ae199e8f19fdafa4c3f1827
ToppCellNS-moderate-d_0-4|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CHL1 DNAH10 FHAD1 CFAP54 VWA3B

8.59e-051931035ea345d34440b25f65358a53dc72831998d1c3620
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.3|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH10 ARFGEF3 FHAD1 CFAP54 VWA3B

8.59e-051931035bdb7401dd9059032f930f2b575f2ef8e504b6594
ToppCell368C-Lymphocytic-B_cell-|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

IL13RA1 RNGTT CCR7 MNDA SH3BP5

8.80e-0519410359a72b6a3217b100617f468aaad48566a04334f3c
ToppCell368C-Lymphocytic-B_cell|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

IL13RA1 RNGTT CCR7 MNDA SH3BP5

8.80e-051941035f8c46c5855a684ed5cb5289da4c29cf3e6052b97
ToppCellPCW_10-12-Endothelial-Endothelial_immature-endo_immature4_(5)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

SLCO2B1 INPP5D ARFGEF3 SLC35F3 SCARB1

8.80e-05194103553a5e8863d79a052dff0758f389be5ac3883c721
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CHL1 ABCC3 RNF213 DST LNPEP

9.01e-051951035938b31dbf1674ee6fd0123bc88391ddcaf151217
ToppCellCOVID-19-kidney-PLVAP+EC|kidney / Disease (COVID-19 only), tissue and cell type

CACNA1C INPP5D FRMD8 F8 SH3BP5

9.01e-051951035a436483fec137584611f86b7a498a4dc2aa19cd3
ToppCellMonocytes-NUPR1+_Monocytes|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

A2M ABCC3 SLCO2B1 SCARB1 MNDA

9.01e-0519510355e12201ce7ba912e7faa123ca200e609252ba288
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_I|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

A2M IL13RA1 SLCO2B1 INPP5D TLR3

9.01e-051951035b6bf75669f267ecdc96818c7022db852e37a9fe1
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CHL1 ABCC3 RNF213 DST LNPEP

9.01e-051951035d39e9e6544f49e677ebe528c6fe60b99a3630e30
ToppCellControl_saline-Epithelial_airway-airway_epithelial-Ciliated|Control_saline / Treatment groups by lineage, cell group, cell type

DNAH10 FHAD1 CFAP54 TRPV4 VWA3B

9.01e-05195103560067b5359174f0d1a8b5748bfc0690762e9e740
ToppCell10x5'v1-week_14-16-Myeloid_macrophage|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

A2M ABCC3 SLCO2B1 ARFGEF3 FAM20C

9.23e-051961035e0447ad2efb021b63c7fef000d39b6b21fbe6113
ToppCellMonocytes|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

A2M ABCC3 SLCO2B1 SCARB1 MNDA

9.23e-051961035ab0a8f5f388c9794d7f41f99fb0a5f2fd6fff6b3
ToppCellfacs-Skin-Telogen-3m-Epithelial-bulge_keratinocyte|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1C DEGS1 DST TRPV4 DMD

9.23e-05196103590edf61116ffcb4f8b6be3d0a05732d59b0a87d5
ToppCellfacs-Skin-Telogen-3m-Epithelial-outer_bulge|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1C DEGS1 DST TRPV4 DMD

9.23e-051961035c936014125b2ed5f796221b74acb77b8f8359875
ToppCell10x5'v1-week_14-16-Myeloid_macrophage-stroma|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

A2M ABCC3 SLCO2B1 ARFGEF3 FAM20C

9.23e-0519610353bca88eede3dd7368715ced02e3bacd1e3e82cab
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_aging_sig-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

A2M SLCO2B1 INPP5D RNF213 MNDA

9.23e-051961035e54c08f88779f9fd453a4f5b85aed1f460d8a1e1
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TMEM144 ARFGEF3 DST PIP4K2A SH3BP5

9.46e-05197103582b8e22317cad6d3786bd70d91107007c0ccd7cd
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_aging_sig-F|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

A2M IL13RA1 SLCO2B1 INPP5D MNDA

9.46e-05197103550f994e0d4e69019ec92e164edf3e4e951333766
ToppCellmLN-(2)_B_cell-(20)_B_cell_IgA_Plasma|mLN / shred on region, Cell_type, and subtype

KNTC1 TEX14 ARFGEF3 VWA3B ACOXL

9.46e-051971035a39b384ee9824a08c3b544a9c3c7f0f95f08d6a7
ToppCellmLN-B_cell-B_cell_IgA_Plasma|mLN / Region, Cell class and subclass

KNTC1 TEX14 ARFGEF3 VWA3B ACOXL

9.46e-05197103520822fce311326765b71337ce501ba44ea14f58f
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Myeloid-Macrophage-macrophage,_alveolar-Macro_c1-C1QC|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

A2M IL13RA1 SLCO2B1 FAM20C MNDA

9.69e-051981035579a22199643440b98e381147779ced630d4ed66
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

A2M IL13RA1 SLCO2B1 INPP5D MNDA

9.69e-05198103500a54af5267bfe0eeab6720bf890dc4b6b803bfd
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

A2M IL13RA1 SLCO2B1 INPP5D MNDA

9.69e-051981035b50074297184bcc044d06e20bb1d3733b9bd8df7
ToppCellCOVID-19-kidney-AQP1+PLVAP+EC|kidney / Disease (COVID-19 only), tissue and cell type

A2M CACNA1C INPP5D F8 SH3BP5

9.69e-0519810358689090bce9ab6e8f122426a404037e572c6713b
ToppCellBronchial-NucSeq-Immune_Myeloid-Macrophage_other-Macro_CHIT1|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ABCC3 SLCO2B1 HTRA4 FAM20C MNDA

9.69e-0519810350b41b3d6c2db795320e8b65d40d85fb8b618cc34
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW26-Myeloid-Microglia|GW26 / Sample Type, Dataset, Time_group, and Cell type.

A2M IL13RA1 SLCO2B1 INPP5D MNDA

9.69e-051981035c0d33629438504a1545e07f0e5af2e76f50fd55b
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW26-Myeloid|GW26 / Sample Type, Dataset, Time_group, and Cell type.

A2M IL13RA1 SLCO2B1 INPP5D MNDA

9.69e-0519810352b93995f66c7352acc25d6c71d025b847881dacd
ToppCellNon-neuronal-Postmitotic-Microglia-Microglia|World / Primary Cells by Cluster

A2M TMEM144 SLCO2B1 INPP5D MNDA

9.69e-05198103576bcdd96e311fe80504e32e9b5fef0b6510c54b6
ToppCell3'_v3-GI_small-bowel-Myeloid_Mac|GI_small-bowel / Manually curated celltypes from each tissue

A2M IL13RA1 SLCO2B1 FAM20C DST

9.92e-0519910358990a3d69e24cb3aaba9d6def3d0be9ee973436d
ToppCell3'_v3-GI_small-bowel-Myeloid_Mac-Intestinal_macrophages|GI_small-bowel / Manually curated celltypes from each tissue

A2M IL13RA1 SLCO2B1 FAM20C DST

9.92e-05199103596070b5ffcbab4952970f43b536969ddd2ca5d14
ToppCellTransverse-Macrophage-LYVE1_Macrophage|Transverse / Region, Cell class and subclass

A2M IL13RA1 SLCO2B1 FAM20C MNDA

9.92e-051991035facf79c256db5ae57bdb613e86ec90616a6f67ca
ToppCellTransverse-(6)_Macrophage-(61)_LYVE1_Macrophage|Transverse / shred on region, Cell_type, and subtype

A2M IL13RA1 SLCO2B1 FAM20C MNDA

9.92e-051991035dcc2a7f4d1fa30aaaad655dd59c5a2b039d264bf
ToppCellNeuron|World / Primary Cells by Cluster

CHL1 ARFGEF3 BHLHE22 ZBTB18 SH3BP5

9.92e-0519910351f8104fd92f04690b41d9d07ac08dc59d76bb97d
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW23-Myeloid-Microglia|GW23 / Sample Type, Dataset, Time_group, and Cell type.

A2M IL13RA1 SLCO2B1 INPP5D MNDA

9.92e-0519910354ddfbcaa8054b69b3398d8c0d5fab8ae94805cb9
ToppCellNeuron-Postmitotic|World / Primary Cells by Cluster

CHL1 ARFGEF3 BHLHE22 ZBTB18 SH3BP5

9.92e-0519910351973527f8a7d4c6490d75c0d0ea153688166a08b
ToppCell(5)_Dendritic_cell|World / shred on Cell_type and subtype

A2M IL13RA1 TMEM144 FAM20C MNDA

9.92e-051991035495de74a918c5c625a2d0ef120fe4162d4ce6e76
ToppCellCOVID-19-kidney-Glomerular_EC|kidney / Disease (COVID-19 only), tissue and cell type

A2M CACNA1C F8 PIP4K2A SH3BP5

9.92e-051991035fffd2f9042b55531dac4e5b463b5cee80402e7bb
ToppCellNeuron-Postmitotic-Excitatory_Neuron_|World / Primary Cells by Cluster

CHL1 ARFGEF3 BHLHE22 ZBTB18 SH3BP5

9.92e-051991035058373b4ac3cec2108cb24265628ff0a50646e33
ToppCellCOVID-19-kidney-Fibroblast-1|kidney / Disease (COVID-19 only), tissue and cell type

A2M CACNA1C DST AGTR1 DMD

9.92e-0519910359503646ff1ad248181146ce767e9d12e882ec3bd
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW23-Myeloid|GW23 / Sample Type, Dataset, Time_group, and Cell type.

A2M IL13RA1 SLCO2B1 INPP5D MNDA

9.92e-0519910353ba48a4715d5e9387650aa97e0c5d7f7897bf380
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_II-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

A2M SLCO2B1 INPP5D RNF213 MNDA

9.92e-051991035e245851a5bddf56f7e13a7fb7c5fda2fd275dae3
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW23-Mesenchymal|GW23 / Sample Type, Dataset, Time_group, and Cell type.

A2M IL13RA1 TMEM144 SLCO2B1 INPP5D

1.02e-0420010350eccf41edefc3b8b5d0316f57d5ba572949aec2b
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW23-Mesenchymal-BMP_responsible_cell|GW23 / Sample Type, Dataset, Time_group, and Cell type.

A2M IL13RA1 TMEM144 SLCO2B1 INPP5D

1.02e-04200103501d707c4f8ee0daac635b7260937b1baebc6fc23
ToppCellSigmoid-Macrophage-Macrophage|Sigmoid / Region, Cell class and subclass

A2M IL13RA1 SLCO2B1 FHAD1 MNDA

1.02e-0420010359ee3a799de7bade1bfe94b6827461633f02bc1dc
Drugsoybean oil, phospholipid emulsion

ABCC3 SLCO2B1 ABCC2

8.67e-0751023ctd:C545823
DrugAC1Q5QTP

ABCC3 RNGTT AGTR1 ABCC2

6.16e-06271024CID000071324
Drugguanosine 3',5'-cyclic monophosphoric acid

KNTC1 CACNA1C ABCC3 MYH1 ABCA4 PDE6C TEX12 GUCY2F AGTR1 TRPV4 DMD ABCC2

1.06e-0557710212CID000000295
DrugMetronidazole

ABCC3 SLCO2B1 ABCC2

1.40e-05111023ctd:D008795
Drug5(6)-carboxy-2',7'-dichlorofluorescein

ABCC3 ABCC2

1.99e-0521022ctd:C053897
DrugE3040 glucuronide

ABCC3 ABCC2

1.99e-0521022CID000443294
DiseaseDyggve-Melchior-Clausen disease (implicated_via_orthology)

RAB8B RAB8A RAB10

1.46e-074993DOID:0111167 (implicated_via_orthology)
DiseaseSmith-McCort dysplasia (implicated_via_orthology)

RAB8B RAB8A RAB10

3.65e-075993DOID:0060247 (implicated_via_orthology)
DiseaseX-24588 measurement

ABCC3 HEATR4 ABCC2

1.02e-0513993EFO_0800898
Diseasebipolar disorder, anorexia nervosa

CACNA1C MAU2

1.66e-046992MONDO_0004985, MONDO_0005351
Diseasebilirubin metabolic disorder (biomarker_via_orthology)

ABCC3 ABCC2

2.31e-047992DOID:2741 (biomarker_via_orthology)
DiseaseTourette syndrome, bipolar disorder

MAU2 CD47

2.31e-047992EFO_0004895, MONDO_0004985
Diseaseserum metabolite measurement

CDC42BPA HEATR4 RAB8B PKD1L1 CKAP5 TMC4 MAU2 NWD2 SCARB1 GHITM ABCC2

3.32e-049459911EFO_0005653
Diseaseimmunoglobulin isotype switching measurement

LAMA3 ATP1A4 ACOXL

4.39e-0444993EFO_0010128
DiseaseAnemia, Sickle Cell

CACNA1C CAD

4.93e-0410992C0002895
Disease2-ketocaprylate measurement

HEATR4 PCNX4

4.93e-0410992EFO_0800110
DiseaseGastrointestinal Stromal Sarcoma

NDST1 DMD DYRK2

5.34e-0447993C3179349
DiseaseColorectal Carcinoma

CHL1 ABCC3 CAD ABCA4 APC2 SACS CCNB3 DMD ABCC2

5.98e-04702999C0009402
Diseasecerebral cavernous malformation (implicated_via_orthology)

CDC42BPA RNF213

6.01e-0411992DOID:0060669 (implicated_via_orthology)
Diseasemaleate measurement, Alpha ketoglutarate measurement, fumarate measurement

EFR3A GHITM

6.01e-0411992EFO_0010457, EFO_0010480, EFO_0010509
DiseaseGastrointestinal Stromal Tumors

NDST1 DMD DYRK2

6.40e-0450993C0238198
Diseaseglycochenodeoxycholate glucuronide (1) measurement

ABCC3 ABCC2

8.48e-0413992EFO_0800474
Diseaseallergic rhinitis

WDR36 LAMA3 DYRK4 CCR7

1.07e-03133994EFO_0005854
DiseaseX-21441 measurement

ABCC3 ABCC2

1.47e-0317992EFO_0800814
DiseaseGrand Mal Status Epilepticus

CCR7 DMD ABCC2

1.50e-0367993C0311335
DiseaseStatus Epilepticus, Subclinical

CCR7 DMD ABCC2

1.50e-0367993C0751522
DiseaseSimple Partial Status Epilepticus

CCR7 DMD ABCC2

1.50e-0367993C0751524
DiseaseNon-Convulsive Status Epilepticus

CCR7 DMD ABCC2

1.50e-0367993C0751523
DiseasePetit mal status

CCR7 DMD ABCC2

1.50e-0367993C0270823
DiseaseComplex Partial Status Epilepticus

CCR7 DMD ABCC2

1.50e-0367993C0393734
DiseaseStatus Epilepticus

CCR7 DMD ABCC2

1.57e-0368993C0038220
DiseaseCOVID-19 (is_implicated_in)

A2M AGTR1

2.24e-0321992DOID:0080600 (is_implicated_in)
Diseasepalmitoylcarnitine measurement

ATP1A4 ACOXL

2.24e-0321992EFO_0021044
Diseasedilated cardiomyopathy (implicated_via_orthology)

MYH1 AGTR1 DMD

2.50e-0380993DOID:12930 (implicated_via_orthology)
DiseaseAnhedonia

CACNA1C CCR7

2.93e-0324992C0178417

Protein segments in the cluster

PeptideGeneStartEntry
YLKALKTEFTTGMIL

AHSA2P

151

Q719I0
SKAIYLMQKALLIFE

CFAP54

846

Q96N23
FGTGLYLTLVRKMKN

ABCA4

1151

P78363
LTLAKGEYKMALKNL

SH3BP5

236

O60239
SKIATLLLAKNYILM

BHLHE22

281

Q8NFJ8
YMKLKTVASVFLLNL

AGTR1

56

P30556
FKRLKTMTDTYLLNL

CCR7

86

P32248
FVLFMKILSGLKSLQ

API5

191

Q9BZZ5
SMGKLYSLKQDLLST

DMD

616

P11532
IKKALLSGYFMQIAR

DHX32

616

Q7L7V1
LLRSLLMVTSGYKAK

EFR3A

436

Q14156
TLLMKFCLLYGTKLV

ACOXL

506

Q9NUZ1
TLLGLKKLSFYYLIM

A2M

486

P01023
SKLAAASLLLALYMK

CCNB3

1301

Q8WWL7
QNYLLESLKGLDKMF

TFAP2E

406

Q6VUC0
DQNLKYLGLLAMSKI

AP3D1

316

O14617
LYTMIKIGQFDKVLS

NWD2

861

Q9ULI1
MLSLKKYLTEGLLQF

NFE2L1

1

Q14494
MAKKTYDLLFKLLLI

RAB10

1

P61026
SLSFLYLKEVMGLKC

PATE4

11

P0C8F1
MAKTYDYLFKLLLIG

RAB8A

1

P61006
MAKTYDYLFKLLLIG

RAB8B

1

Q92930
MSEILNGIKVLKLYA

ABCC3

491

O15438
MLVNFLGKKNTILYS

OR8D1

81

Q8WZ84
MSYAFLLALLKKLSG

OR4M2B

216

A0A0X1KG70
TLNKLGIDGMYLKII

nan

616

O00370
LRFKYLLKQALATGM

H1-8

91

Q8IZA3
KNSFMALYLSKGRLV

LAMA3

3031

Q16787
AKLLPNYLRLDKMTF

KIAA0825

1216

Q8IV33
NYLRLDKMTFSVLLK

KIAA0825

1221

Q8IV33
SNYLKSLKVKMGLLV

RNGTT

51

O60942
IVYLMFLLLKFSKAI

CHL1

11

O00533
LFSMFLLYDTQKVIK

GHITM

286

Q9H3K2
GLSQLILQKLNMKSY

MSS51

56

Q4VC12
ARLLKANNTLLKMGY

LMOD3

361

Q0VAK6
ELLQYKSTIANLMGK

DST

856

Q03001
LKIYSKQAELMSSLI

FRMD8

351

Q9BZ67
LKIYSKQAELMSSLI

FRMD8P1

351

Q9BZ68
FRYTLKLMIDKASLG

PCNX4

1026

Q63HM2
IYLTRLLSMKGTLQK

PLXNB3

1691

Q9ULL4
MSYAFLLALFKKLSG

OR4M2

216

Q8NGB6
TLLMTGRLKKYYTDL

PDE6C

576

P51160
IYFRKGKFLLMLQSV

NAA16

681

Q6N069
AISTLLKKNMLLYFA

CSTF3

331

Q12996
NIELSKLLYKMGQTL

NDST1

856

P52848
SLSYFKGSSLLLMLK

LNPEP

546

Q9UIQ6
KGSSLLLMLKTYLSE

LNPEP

551

Q9UIQ6
LLISKLMKFSLDTLY

KNTC1

1621

P50748
KTFYMVLLKSFLLKL

ABCC2

316

Q92887
IMNEILSGIKILKYF

ABCC2

501

Q92887
GVKSLLTSMYVKEFL

F8

2266

P00451
LYQKSAMKTLALLFV

MYH1

611

P12882
IGKKRNSTLYITMLL

IL13RA1

336

P78552
ITFELLGINLYELMK

DYRK4

181

Q9NR20
LKALQMDITSLYNLK

APC2

76

O95996
TNTSVLMKALEYLKL

CKAP5

1256

Q14008
SNKKYLGLQMLSLTV

HTRA4

376

P83105
LSEKLYLDMSKTLGS

FHAD1

1241

B1AJZ9
LFTAEMLLKMYSLGL

CACNA1C

566

Q13936
LQLLAKEEYKLSLLM

FAM20C

511

Q8IXL6
KLNLMALGGFLYQLK

ARFGEF3

1131

Q5TH69
TDLMQKLYLLFSTEK

COL6A5

2566

A8TX70
KLYLLFSTEKLAMKD

COL6A5

2571

A8TX70
FKSSLLLDLIKGMKY

GUCY2F

646

P51841
ALYLIGELKLMTAKL

HEATR4

716

Q86WZ0
IKSLVYMLAASLLGL

DEGS1

206

O15121
IKNALASKMLYEFIL

IFRD1

106

O00458
SILALAQLLGLVYMK

CD47

276

Q08722
YLKLGIENKAMIFLF

DNAH10

2846

Q8IVF4
IPSRKDLFMNTLYLK

SACS

3181

Q9NZJ4
EYTRALFLLSKGMLL

MAU2

181

Q9Y6X3
FELLSMNLYELIKKN

DYRK2

301

Q92630
SNKLGFMSAVLILKY

PKD1L1

1381

Q8TDX9
LAQLKLMDYSLLVGI

PIP4K2A

266

P48426
SMGASYSKSLIKLLL

FANCD2

126

Q9BXW9
KELKGMLNLKILSLY

LRRC72

131

A6NJI9
KSLLAYDLGLTTKMQ

MNDA

26

P41218
MQAIIQGFSYDLLKK

TEX14

151

Q8IWB6
KKYLLDGISYLLQML

RIMOC1

161

A6NDU8
LYLGSTLSLVKKLPM

IQCA1L

516

A6NCM1
LGYLIIKGKQMFALS

SKIDA1

16

Q1XH10
YMNILRFLALGDKKL

INPP5D

556

Q92835
VKLQLSLYMKSVAGI

SCARB1

386

Q8WTV0
ILGSFELQLYTGKKM

TGM4

506

P49221
LGLETIRLIYFKNKM

CDC42BPA

1501

Q5VT25
SASMSALYKVLFKLL

SLC35F3

241

Q8IY50
GLAMFYLLLSLLMIK

SERINC1

96

Q9NRX5
GRLIFDNLKKSIMYT

ATP1A4

771

Q13733
QLLKKELGLYQLAMD

CNBD2

11

Q96M20
FKLLILQYLMDINGK

RNF213

2071

Q63HN8
ILKSTLKGLEYLHFM

STK3

126

Q13188
KSNMFTGLINLKYLS

TLR3

371

O15455
AETLLPLLSLMGYFK

MINPP1

371

Q9UNW1
FSLILKILSMIYKLV

SPO11

111

Q9Y5K1
SLLQLAQLMISGYLK

SLCO2B1

56

O94956
LILSKTETNVYFKLM

PPAN

86

Q9NQ55
IFMFKEIKGLQNYLL

TMEM144

311

Q7Z5S9
GQEMYKLLLFDLLTV

TMC4

481

Q7Z404
ALLLEFMYEGKLQFK

ZBTB18

76

Q99592
QLLALAIGAKTYKMR

CAD

256

P27708
LSIMLYSSKKEINAL

ZZEF1

2406

O43149
TYGLVAKKLTLMDAL

VWA3B

851

Q502W6
SSLLMDLKYKKLFAV

UBR2

376

Q8IWV8
LEEKSLSLKIMQYFS

TG

2646

P01266
KFCGKALMFLSLYLI

ZNF433

201

Q8N7K0
LKLTGTYSIMIQKIL

TRPV4

596

Q9HBA0
SKEINLMLSTYAKLL

TEX12

61

Q9BXU0
YLALFLKLHLKMLPS

WDR36

896

Q8NI36
ALKRSFKELGLLLMY

KCNF1

316

Q9H3M0