Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncalcium ion binding

JAG2 NELL1 FBLN7 EYS SCUBE1 LTBP2 FBN1 EFEMP1 MEGF6 MEGF8 AGRN SVEP1 NOTCH1 JAG1 NOTCH3 SLIT3

1.35e-137493816GO:0005509
GeneOntologyMolecularFunctionextracellular matrix structural constituent

LAMA5 PAPLN LTBP2 FBN1 EFEMP1 IGFBP6 AGRN

5.78e-08188387GO:0005201
GeneOntologyMolecularFunctionglycosaminoglycan binding

NELL1 FBLN7 LTBP2 FBN1 AGRN SLIT3

1.06e-05268386GO:0005539
GeneOntologyMolecularFunctionNotch binding

JAG2 NOTCH1 JAG1

1.80e-0527383GO:0005112
GeneOntologyMolecularFunctionheparin binding

NELL1 FBLN7 LTBP2 FBN1 SLIT3

3.03e-05192385GO:0008201
GeneOntologyMolecularFunctionsulfur compound binding

NELL1 FBLN7 LTBP2 FBN1 AGRN SLIT3

3.05e-05323386GO:1901681
GeneOntologyMolecularFunctiontranscription regulator activator activity

NOTCH1 NSD3

1.57e-0410382GO:0140537
GeneOntologyMolecularFunctionstructural molecule activity

LAMA5 PAPLN LTBP2 FBN1 EFEMP1 IGFBP6 AGRN JAG1

2.26e-04891388GO:0005198
GeneOntologyMolecularFunctionextracellular matrix binding

LTBP2 ZAN AGRN

3.61e-0473383GO:0050840
GeneOntologyMolecularFunctionheparan sulfate proteoglycan binding

FBLN7 AGRN

1.39e-0329382GO:0043395
GeneOntologyMolecularFunctionmolecular function activator activity

ADGRB3 JAG2 FBN1 EFEMP1 AGRN NOTCH1 JAG1 NSD3

1.92e-031233388GO:0140677
GeneOntologyMolecularFunctiongrowth factor binding

LTBP2 IGFBP6 AGRN

3.23e-03156383GO:0019838
GeneOntologyMolecularFunctionreceptor ligand activity

JAG2 FBN1 EFEMP1 AGRN JAG1

3.60e-03547385GO:0048018
GeneOntologyMolecularFunctionsignaling receptor activator activity

JAG2 FBN1 EFEMP1 AGRN JAG1

3.80e-03554385GO:0030546
GeneOntologyMolecularFunctionproteoglycan binding

FBLN7 AGRN

4.24e-0351382GO:0043394
GeneOntologyMolecularFunctiongrowth factor activity

JAG2 EFEMP1 JAG1

4.32e-03173383GO:0008083
GeneOntologyMolecularFunctionintegrin binding

LAMA5 FBN1 SVEP1

4.46e-03175383GO:0005178
GeneOntologyMolecularFunctionsignaling receptor regulator activity

JAG2 FBN1 EFEMP1 AGRN JAG1

5.95e-03616385GO:0030545
GeneOntologyBiologicalProcessaxon guidance

LAMA5 MEGF8 AGRN NOTCH1 NOTCH3 SLIT3

1.26e-05285386GO:0007411
GeneOntologyBiologicalProcessneuron projection guidance

LAMA5 MEGF8 AGRN NOTCH1 NOTCH3 SLIT3

1.28e-05286386GO:0097485
GeneOntologyBiologicalProcessartery morphogenesis

MEGF8 NOTCH1 JAG1 NOTCH3

2.44e-0592384GO:0048844
GeneOntologyBiologicalProcessinner ear receptor cell differentiation

JAG2 OTOGL NOTCH1 JAG1

2.88e-0596384GO:0060113
GeneOntologyBiologicalProcessmechanoreceptor differentiation

JAG2 OTOGL NOTCH1 JAG1

3.95e-05104384GO:0042490
GeneOntologyBiologicalProcessinner ear receptor cell fate commitment

JAG2 NOTCH1

4.93e-056382GO:0060120
GeneOntologyBiologicalProcessauditory receptor cell fate commitment

JAG2 NOTCH1

4.93e-056382GO:0009912
GeneOntologyBiologicalProcessinhibition of neuroepithelial cell differentiation

NOTCH1 JAG1

4.93e-056382GO:0002085
GeneOntologyBiologicalProcessaortic valve morphogenesis

NOTCH1 JAG1 SLIT3

5.04e-0539383GO:0003180
GeneOntologyBiologicalProcesscell morphogenesis involved in neuron differentiation

ADGRB3 LAMA5 MEGF8 AGRN NOTCH1 NOTCH3 SLIT3 ADGRB1

5.36e-05748388GO:0048667
GeneOntologyBiologicalProcessaxonogenesis

LAMA5 MEGF8 AGRN NOTCH1 NOTCH3 SLIT3 ADGRB1

6.80e-05566387GO:0007409
GeneOntologyBiologicalProcessneuron projection development

ADGRB3 LAMA5 EFEMP1 MEGF8 OTOGL AGRN NOTCH1 NOTCH3 SLIT3 ADGRB1

8.06e-0512853810GO:0031175
GeneOntologyBiologicalProcessaortic valve development

NOTCH1 JAG1 SLIT3

8.29e-0546383GO:0003176
GeneOntologyBiologicalProcessneuron projection morphogenesis

ADGRB3 LAMA5 MEGF8 AGRN NOTCH1 NOTCH3 SLIT3 ADGRB1

8.75e-05802388GO:0048812
GeneOntologyBiologicalProcessplasma membrane bounded cell projection morphogenesis

ADGRB3 LAMA5 MEGF8 AGRN NOTCH1 NOTCH3 SLIT3 ADGRB1

1.01e-04819388GO:0120039
GeneOntologyBiologicalProcessartery development

MEGF8 NOTCH1 JAG1 NOTCH3

1.03e-04133384GO:0060840
GeneOntologyBiologicalProcesssemi-lunar valve development

NOTCH1 JAG1 SLIT3

1.07e-0450383GO:1905314
GeneOntologyBiologicalProcesspositive regulation of nervous system development

ADGRB3 RASSF10 MEGF8 AGRN NOTCH1 ADGRB1

1.07e-04418386GO:0051962
GeneOntologyBiologicalProcesscell projection morphogenesis

ADGRB3 LAMA5 MEGF8 AGRN NOTCH1 NOTCH3 SLIT3 ADGRB1

1.07e-04826388GO:0048858
GeneOntologyBiologicalProcesspositive regulation of cardiac epithelial to mesenchymal transition

NOTCH1 JAG1

1.18e-049382GO:0062043
GeneOntologyBiologicalProcesspositive regulation of Notch signaling pathway

JAG2 NOTCH1 JAG1

1.27e-0453383GO:0045747
GeneOntologyBiologicalProcessdistal tubule development

NOTCH1 JAG1

1.47e-0410382GO:0072017
GeneOntologyBiologicalProcessaxon development

LAMA5 MEGF8 AGRN NOTCH1 NOTCH3 SLIT3 ADGRB1

1.49e-04642387GO:0061564
GeneOntologyBiologicalProcesscirculatory system development

ADGRB3 SCUBE1 FBN1 MEGF8 SVEP1 NOTCH1 JAG1 NOTCH3 SLIT3 ADGRB1

2.09e-0414423810GO:0072359
GeneOntologyBiologicalProcessheart valve morphogenesis

NOTCH1 JAG1 SLIT3

2.12e-0463383GO:0003179
GeneOntologyBiologicalProcessneuron development

ADGRB3 LAMA5 EFEMP1 MEGF8 OTOGL AGRN NOTCH1 NOTCH3 SLIT3 ADGRB1

2.35e-0414633810GO:0048666
GeneOntologyBiologicalProcessenzyme-linked receptor protein signaling pathway

VWC2L LTBP2 FBN1 EFEMP1 IGFBP6 MEGF8 AGRN SVEP1 NOTCH1

2.39e-041186389GO:0007167
GeneOntologyBiologicalProcessinner ear auditory receptor cell differentiation

JAG2 NOTCH1 JAG1

2.55e-0467383GO:0042491
GeneOntologyBiologicalProcessnephron development

LAMA5 NOTCH1 JAG1 NOTCH3

2.89e-04174384GO:0072006
GeneOntologyBiologicalProcessregulation of cardiac epithelial to mesenchymal transition

NOTCH1 JAG1

2.97e-0414382GO:0062042
GeneOntologyBiologicalProcessmorphogenesis of an epithelial sheet

MEGF8 NOTCH1 JAG1

3.42e-0474383GO:0002011
GeneOntologyBiologicalProcessregulation of timing of cell differentiation

NOTCH1 JAG1

3.42e-0415382GO:0048505
GeneOntologyBiologicalProcessglomerulus development

NOTCH1 JAG1 NOTCH3

3.84e-0477383GO:0032835
GeneOntologyBiologicalProcessneuroendocrine cell differentiation

NOTCH1 JAG1

3.90e-0416382GO:0061101
GeneOntologyBiologicalProcessheart valve development

NOTCH1 JAG1 SLIT3

3.99e-0478383GO:0003170
GeneOntologyBiologicalProcesshair cell differentiation

JAG2 NOTCH1 JAG1

3.99e-0478383GO:0035315
GeneOntologyBiologicalProcessnegative regulation of BMP signaling pathway

VWC2L FBN1 NOTCH1

4.30e-0480383GO:0030514
GeneOntologyBiologicalProcessaorta development

MEGF8 NOTCH1 JAG1

4.30e-0480383GO:0035904
GeneOntologyBiologicalProcessregulation of development, heterochronic

NOTCH1 JAG1

4.42e-0417382GO:0040034
GeneOntologyBiologicalProcessBMP signaling pathway

VWC2L FBN1 MEGF8 NOTCH1

4.62e-04197384GO:0030509
GeneOntologyBiologicalProcesspositive regulation of synapse assembly

ADGRB3 AGRN ADGRB1

5.31e-0486383GO:0051965
GeneOntologyBiologicalProcesskidney development

LAMA5 FBN1 NOTCH1 JAG1 NOTCH3

5.72e-04372385GO:0001822
GeneOntologyBiologicalProcesscardiac septum morphogenesis

NOTCH1 JAG1 SLIT3

5.87e-0489383GO:0060411
GeneOntologyBiologicalProcessNotch signaling pathway

JAG2 NOTCH1 JAG1 NOTCH3

5.88e-04210384GO:0007219
GeneOntologyBiologicalProcesspulmonary valve morphogenesis

NOTCH1 JAG1

6.15e-0420382GO:0003184
GeneOntologyBiologicalProcessneuron fate commitment

JAG2 NOTCH1 NOTCH3

6.27e-0491383GO:0048663
GeneOntologyBiologicalProcessresponse to BMP

VWC2L FBN1 MEGF8 NOTCH1

6.42e-04215384GO:0071772
GeneOntologyBiologicalProcesscellular response to BMP stimulus

VWC2L FBN1 MEGF8 NOTCH1

6.42e-04215384GO:0071773
GeneOntologyBiologicalProcessrespiratory gaseous exchange by respiratory system

ADH5 JAG2 TRAF4

6.68e-0493383GO:0007585
GeneOntologyBiologicalProcessrenal system development

LAMA5 FBN1 NOTCH1 JAG1 NOTCH3

6.75e-04386385GO:0072001
GeneOntologyBiologicalProcessresponse to muramyl dipeptide

NOTCH1 JAG1

6.79e-0421382GO:0032495
GeneOntologyBiologicalProcesscardiac right ventricle morphogenesis

NOTCH1 JAG1

6.79e-0421382GO:0003215
GeneOntologyBiologicalProcessnegative regulation of neuron differentiation

NOTCH1 JAG1 NOTCH3

6.89e-0494383GO:0045665
GeneOntologyBiologicalProcessaxon extension involved in axon guidance

MEGF8 SLIT3

7.46e-0422382GO:0048846
GeneOntologyBiologicalProcessneuron projection extension involved in neuron projection guidance

MEGF8 SLIT3

7.46e-0422382GO:1902284
GeneOntologyBiologicalProcessregulation of embryonic development

LAMA5 NOTCH1 JAG1

8.01e-0499383GO:0045995
GeneOntologyBiologicalProcesstube development

ADGRB3 LAMA5 TRAF4 FBN1 MEGF8 NOTCH1 JAG1 NOTCH3 ADGRB1

8.13e-041402389GO:0035295
GeneOntologyBiologicalProcesspulmonary valve development

NOTCH1 JAG1

8.89e-0424382GO:0003177
GeneOntologyBiologicalProcessregulation of nervous system development

ADGRB3 RASSF10 MEGF8 AGRN NOTCH1 ADGRB1

9.13e-04625386GO:0051960
GeneOntologyBiologicalProcessnephron tubule development

LAMA5 NOTCH1 JAG1

1.09e-03110383GO:0072080
GeneOntologyBiologicalProcessinner ear development

JAG2 OTOGL NOTCH1 JAG1

1.18e-03253384GO:0048839
GeneOntologyBiologicalProcessregulation of Notch signaling pathway

JAG2 NOTCH1 JAG1

1.20e-03114383GO:0008593
GeneOntologyBiologicalProcessregulation of neuron differentiation

VWC2L NOTCH1 JAG1 NOTCH3

1.21e-03255384GO:0045664
GeneOntologyBiologicalProcessatrioventricular valve morphogenesis

NOTCH1 SLIT3

1.21e-0328382GO:0003181
GeneOntologyBiologicalProcessrenal tubule development

LAMA5 NOTCH1 JAG1

1.27e-03116383GO:0061326
GeneOntologyBiologicalProcesscell morphogenesis

ADGRB3 LAMA5 MEGF8 AGRN NOTCH1 NOTCH3 SLIT3 ADGRB1

1.27e-031194388GO:0000902
GeneOntologyBiologicalProcesstransforming growth factor beta receptor superfamily signaling pathway

VWC2L LTBP2 FBN1 MEGF8 NOTCH1

1.28e-03445385GO:0141091
GeneOntologyBiologicalProcessglomerulus vasculature development

NOTCH1 NOTCH3

1.39e-0330382GO:0072012
GeneOntologyBiologicalProcesskidney vasculature development

NOTCH1 NOTCH3

1.49e-0331382GO:0061440
GeneOntologyBiologicalProcessrenal system vasculature development

NOTCH1 NOTCH3

1.49e-0331382GO:0061437
GeneOntologyBiologicalProcessepidermis development

JAG2 LAMA5 SVEP1 NOTCH1 JAG1

1.49e-03461385GO:0008544
GeneOntologyBiologicalProcessrespiratory tube development

LAMA5 TRAF4 FBN1 NOTCH1

1.56e-03273384GO:0030323
GeneOntologyBiologicalProcessapoptotic process involved in morphogenesis

JAG2 NOTCH1

1.58e-0332382GO:0060561
GeneOntologyBiologicalProcessatrioventricular valve development

NOTCH1 SLIT3

1.58e-0332382GO:0003171
GeneOntologyBiologicalProcessnephron epithelium development

LAMA5 NOTCH1 JAG1

1.68e-03128383GO:0072009
GeneOntologyBiologicalProcessnegative regulation of stem cell differentiation

NOTCH1 JAG1

1.68e-0333382GO:2000737
GeneOntologyBiologicalProcessvasculature development

ADGRB3 MEGF8 SVEP1 NOTCH1 JAG1 NOTCH3 ADGRB1

1.74e-03969387GO:0001944
GeneOntologyBiologicalProcessregulation of BMP signaling pathway

VWC2L FBN1 NOTCH1

1.80e-03131383GO:0030510
GeneOntologyBiologicalProcesscell surface receptor protein serine/threonine kinase signaling pathway

VWC2L LTBP2 FBN1 MEGF8 NOTCH1

1.81e-03482385GO:0007178
GeneOntologyBiologicalProcessear development

JAG2 OTOGL NOTCH1 JAG1

1.82e-03285384GO:0043583
GeneOntologyBiologicalProcesscardiac septum development

NOTCH1 JAG1 SLIT3

1.92e-03134383GO:0003279
GeneOntologyBiologicalProcesspositive regulation of cell junction assembly

ADGRB3 AGRN ADGRB1

2.00e-03136383GO:1901890
GeneOntologyBiologicalProcessheart development

SCUBE1 FBN1 MEGF8 NOTCH1 JAG1 SLIT3

2.42e-03757386GO:0007507
GeneOntologyBiologicalProcesscardiac epithelial to mesenchymal transition

NOTCH1 JAG1

2.47e-0340382GO:0060317
GeneOntologyBiologicalProcessaorta morphogenesis

NOTCH1 JAG1

2.59e-0341382GO:0035909
GeneOntologyBiologicalProcessnegative regulation of cellular response to growth factor stimulus

VWC2L FBN1 NOTCH1

2.64e-03150383GO:0090288
GeneOntologyBiologicalProcessheart morphogenesis

MEGF8 NOTCH1 JAG1 SLIT3

2.80e-03321384GO:0003007
GeneOntologyBiologicalProcesscomplement activation, classical pathway

IGHA1 SVEP1

2.98e-0344382GO:0006958
GeneOntologyBiologicalProcessendothelial cell differentiation

SCUBE1 NOTCH1 JAG1

3.06e-03158383GO:0045446
GeneOntologyBiologicalProcesscardiac chamber morphogenesis

NOTCH1 JAG1 SLIT3

3.22e-03161383GO:0003206
GeneOntologyBiologicalProcesscardiac ventricle development

NOTCH1 JAG1 SLIT3

3.22e-03161383GO:0003231
GeneOntologyCellularComponentextracellular matrix

LAMA5 PAPLN FBLN7 EYS LTBP2 FBN1 EFEMP1 ADAMTS14 ZAN MEGF6 IGFBP6 OTOGL AGRN SVEP1

3.78e-126563814GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

LAMA5 PAPLN FBLN7 EYS LTBP2 FBN1 EFEMP1 ADAMTS14 ZAN MEGF6 IGFBP6 OTOGL AGRN SVEP1

3.93e-126583814GO:0030312
GeneOntologyCellularComponentcollagen-containing extracellular matrix

LAMA5 PAPLN EYS LTBP2 FBN1 EFEMP1 MEGF6 IGFBP6 AGRN

3.43e-07530389GO:0062023
GeneOntologyCellularComponentbasement membrane

LAMA5 PAPLN FBN1 EFEMP1 AGRN

2.68e-06122385GO:0005604
GeneOntologyCellularComponentsynaptic cleft

ADGRB3 LAMA5 AGRN

2.91e-0533383GO:0043083
HumanPhenoAplasia/Hypoplasia of fingers

LAMA5 LTBP2 FBN1 MEGF8 NOTCH1 SCN2A JAG1

2.06e-05366147HP:0006265
HumanPhenoDural ectasia

FBN1 EFEMP1 NOTCH3

3.23e-0524143HP:0100775
HumanPhenoAbnormal spinal meningeal morphology

FBN1 EFEMP1 NOTCH3

3.67e-0525143HP:0010303
HumanPhenoMicrospherophakia

LTBP2 FBN1

4.20e-054142HP:0030961
HumanPhenoBrachydactyly (hand)

LAMA5 LTBP2 FBN1 MEGF8 NOTCH1 SCN2A JAG1

5.92e-05430147HP:0100667
HumanPhenoAbnormal thorax morphology

JAG2 LAMA5 LTBP2 FBN1 EFEMP1 MEGF8 AGRN NOTCH1 SCN2A JAG1 NOTCH3

5.93e-0513281411HP:0000765
HumanPhenoIridodonesis

LTBP2 FBN1

6.98e-055142HP:0100693
HumanPhenoSpherophakia

LTBP2 FBN1

6.98e-055142HP:0034375
HumanPhenoShort phalanx of finger

LAMA5 FBN1 MEGF8 NOTCH1 SCN2A JAG1

8.91e-05306146HP:0009803
HumanPhenoAbnormal sternum morphology

LAMA5 LTBP2 FBN1 EFEMP1 MEGF8 AGRN NOTCH3

1.11e-04474147HP:0000766
HumanPhenoAplasia/Hypoplasia of the phalanges of the hand

LAMA5 FBN1 MEGF8 NOTCH1 SCN2A JAG1

1.13e-04319146HP:0009767
HumanPhenoShort finger

LAMA5 LTBP2 FBN1 NOTCH1 SCN2A JAG1

1.25e-04325146HP:0009381
HumanPhenoNarrow face

FBN1 EFEMP1 MEGF8 NOTCH3

1.62e-04108144HP:0000275
HumanPhenoEctropion of lower eyelids

EFEMP1 MEGF8

1.95e-048142HP:0007651
HumanPhenoChorioretinal atrophy

EYS EFEMP1 JAG1

2.05e-0444143HP:0000533
HumanPhenoAplasia/hypoplasia involving bones of the hand

LAMA5 LTBP2 FBN1 MEGF8 NOTCH1 SCN2A JAG1

2.49e-04538147HP:0005927
HumanPhenoAplasia/hypoplasia involving bones of the upper limbs

LAMA5 LTBP2 FBN1 MEGF8 NOTCH1 SCN2A JAG1

3.67e-04572147HP:0006496
HumanPhenoChorioretinal degeneration

EYS EFEMP1 JAG1

3.77e-0454143HP:0200065
HumanPhenoAbnormal cardiac septum morphology

LAMA5 LTBP2 FBN1 MEGF8 NOTCH1 SCN2A JAG1 NOTCH3

3.95e-04787148HP:0001671
HumanPhenoSmall face

FBN1 EFEMP1 MEGF8 NOTCH3

4.66e-04142144HP:0000274
HumanPhenoCardiac valve calcification

FBN1 NOTCH1

5.38e-0413142HP:0005146
MousePhenoincreased cochlear hair cell number

JAG2 NOTCH1 JAG1

1.10e-0520313MP:0004407
MousePhenoherniated intestine

EFEMP1 SLIT3

2.85e-054312MP:0005155
MousePhenoincreased sensory neuron number

JAG2 NOTCH1 JAG1

9.94e-0541313MP:0006006
MousePhenoabnormal cutaneous elastic fiber morphology

FBN1 EFEMP1

1.32e-048312MP:0008418
MousePhenodouble outlet right ventricle, Taussig bing type

MEGF8 SLIT3

1.70e-049312MP:0011668
MousePhenoabnormal axial skeleton morphology

JAG2 LAMA5 NELL1 TRAF4 SCUBE1 FBN1 EFEMP1 MEGF8 VWDE NOTCH1 NOTCH3

1.79e-0414583111MP:0002114
MousePhenoabnormal cochlear outer hair cell number

JAG2 NOTCH1 JAG1

1.80e-0450313MP:0004400
MousePhenoabnormal viscerocranium morphology

JAG2 LAMA5 NELL1 SCUBE1 FBN1 MEGF8 VWDE

2.58e-04593317MP:0005274
MousePhenoabsent neurocranium

LAMA5 SCUBE1

2.59e-0411312MP:0000075
MousePhenoincreased cochlear inner hair cell number

JAG2 JAG1

4.26e-0414312MP:0004395
MousePhenoabnormal cochlear hair cell number

JAG2 NOTCH1 JAG1

4.49e-0468313MP:0004406
MousePhenocraniofacial phenotype

JAG2 LAMA5 NELL1 SCUBE1 FBN1 MEGF8 VWDE NOTCH1 JAG1 NSD3

5.17e-0413723110MP:0005382
MousePhenoabnormal craniofacial morphology

JAG2 LAMA5 NELL1 SCUBE1 FBN1 MEGF8 VWDE NOTCH1 JAG1 NSD3

5.17e-0413723110MP:0000428
MousePhenoincreased neuron number

JAG2 NOTCH1 JAG1

5.31e-0472313MP:0008947
MousePhenoincreased cochlear outer hair cell number

JAG2 NOTCH1

5.60e-0416312MP:0004401
MousePhenoabnormal heart position or orientation

LAMA5 MEGF8 SLIT3

5.75e-0474313MP:0006065
MousePhenoabnormal spine curvature

NELL1 TRAF4 FBN1 EFEMP1 NOTCH3

6.17e-04318315MP:0004174
MousePhenoabnormal digit morphology

JAG2 LAMA5 FBN1 MEGF8 AGRN

6.62e-04323315MP:0002110
DomainEGF

JAG2 LAMA5 NELL1 FBLN7 EYS SCUBE1 LTBP2 FBN1 EFEMP1 ZAN MEGF6 MEGF8 PGAP6 AGRN VWDE SVEP1 NOTCH1 JAG1 NOTCH3 SLIT3

5.73e-292353720SM00181
DomainEGF-like_dom

JAG2 LAMA5 NELL1 FBLN7 EYS SCUBE1 LTBP2 FBN1 EFEMP1 ZAN MEGF6 MEGF8 PGAP6 AGRN VWDE SVEP1 NOTCH1 JAG1 NOTCH3 SLIT3

1.89e-282493720IPR000742
DomainEGF_1

JAG2 LAMA5 NELL1 FBLN7 EYS SCUBE1 LTBP2 FBN1 EFEMP1 ZAN MEGF6 MEGF8 PGAP6 AGRN VWDE SVEP1 NOTCH1 JAG1 NOTCH3 SLIT3

3.09e-282553720PS00022
DomainEGF-like_CS

JAG2 LAMA5 NELL1 FBLN7 EYS SCUBE1 LTBP2 FBN1 EFEMP1 ZAN MEGF6 MEGF8 PGAP6 AGRN VWDE SVEP1 NOTCH1 JAG1 NOTCH3 SLIT3

4.98e-282613720IPR013032
DomainEGF_2

JAG2 LAMA5 NELL1 FBLN7 EYS SCUBE1 LTBP2 FBN1 EFEMP1 ZAN MEGF6 MEGF8 PGAP6 AGRN VWDE SVEP1 NOTCH1 JAG1 NOTCH3 SLIT3

6.80e-282653720PS01186
DomainEGF_3

JAG2 NELL1 FBLN7 EYS SCUBE1 LTBP2 FBN1 EFEMP1 ZAN MEGF6 MEGF8 PGAP6 AGRN VWDE SVEP1 NOTCH1 JAG1 NOTCH3 SLIT3

5.44e-272353719PS50026
DomainEGF_CA

JAG2 NELL1 FBLN7 EYS SCUBE1 LTBP2 FBN1 EFEMP1 MEGF6 MEGF8 AGRN SVEP1 NOTCH1 JAG1 NOTCH3 SLIT3

4.55e-261223716SM00179
DomainEGF-like_Ca-bd_dom

JAG2 NELL1 FBLN7 EYS SCUBE1 LTBP2 FBN1 EFEMP1 MEGF6 MEGF8 AGRN SVEP1 NOTCH1 JAG1 NOTCH3 SLIT3

5.99e-261243716IPR001881
DomainEGF_Ca-bd_CS

JAG2 NELL1 FBLN7 EYS SCUBE1 LTBP2 FBN1 EFEMP1 MEGF6 MEGF8 SVEP1 NOTCH1 JAG1 NOTCH3 SLIT3

1.48e-25973715IPR018097
DomainEGF_CA

JAG2 NELL1 FBLN7 EYS SCUBE1 LTBP2 FBN1 EFEMP1 MEGF6 MEGF8 SVEP1 NOTCH1 JAG1 NOTCH3 SLIT3

2.06e-25993715PS01187
DomainEGF-type_Asp/Asn_hydroxyl_site

JAG2 NELL1 FBLN7 EYS SCUBE1 LTBP2 FBN1 EFEMP1 MEGF6 MEGF8 SVEP1 NOTCH1 JAG1 NOTCH3 SLIT3

6.15e-251063715IPR000152
DomainGrowth_fac_rcpt_

JAG2 LAMA5 NELL1 EYS SCUBE1 LTBP2 FBN1 EFEMP1 MEGF6 IGFBP6 MEGF8 SVEP1 NOTCH1 JAG1 NOTCH3 SLIT3

2.83e-241563716IPR009030
DomainASX_HYDROXYL

JAG2 NELL1 FBLN7 EYS SCUBE1 LTBP2 FBN1 EFEMP1 MEGF6 MEGF8 SVEP1 NOTCH1 JAG1 NOTCH3

3.41e-231003714PS00010
DomainEGF_CA

JAG2 NELL1 FBLN7 SCUBE1 LTBP2 FBN1 EFEMP1 MEGF6 MEGF8 SVEP1 NOTCH1 JAG1 NOTCH3

5.28e-22863713PF07645
DomainEGF

JAG2 FBLN7 EYS LTBP2 ZAN MEGF6 AGRN SVEP1 NOTCH1 JAG1 NOTCH3 SLIT3

8.35e-181263712PF00008
DomainhEGF

JAG2 EYS MEGF6 SVEP1 NOTCH1 JAG1 NOTCH3

7.53e-1428377PF12661
DomainEGF_extracell

JAG2 NELL1 LTBP2 MEGF6 SVEP1 NOTCH1 JAG1 NOTCH3

2.51e-1360378IPR013111
DomainEGF_2

JAG2 NELL1 LTBP2 MEGF6 SVEP1 NOTCH1 JAG1 NOTCH3

2.51e-1360378PF07974
DomainVWC

JAG2 VWC2L NELL1 ZAN JAG1

1.10e-0838375SM00214
DomainVWF_dom

JAG2 VWC2L NELL1 ZAN JAG1

1.86e-0842375IPR001007
DomainLamG

LAMA5 NELL1 EYS AGRN SLIT3

2.37e-0844375SM00282
Domain-

LAMA5 NELL1 EYS AGRN SVEP1 SLIT3

3.02e-08953762.60.120.200
DomainVWC_out

JAG2 NELL1 ZAN JAG1

4.94e-0819374SM00215
DomainLaminin_G

LAMA5 NELL1 EYS AGRN SLIT3

9.78e-0858375IPR001791
DomainConA-like_dom

LAMA5 NELL1 EYS ZAN AGRN SVEP1 SLIT3

2.11e-07219377IPR013320
DomainLaminin_EGF

LAMA5 MEGF6 MEGF8 AGRN

6.53e-0735374PF00053
DomainEGF_Lam

LAMA5 MEGF6 MEGF8 AGRN

6.53e-0735374SM00180
DomainVWFC_1

JAG2 VWC2L NELL1 ZAN

7.34e-0736374PS01208
DomainLAM_G_DOMAIN

LAMA5 EYS AGRN SLIT3

9.17e-0738374PS50025
DomainLaminin_EGF

LAMA5 MEGF6 MEGF8 AGRN

9.17e-0738374IPR002049
DomainVWFC_2

JAG2 VWC2L NELL1 ZAN

9.17e-0738374PS50184
DomainLaminin_G_2

LAMA5 NELL1 EYS SLIT3

1.13e-0640374PF02210
DomainEGF_3

NELL1 SCUBE1 MEGF8

1.56e-0612373PF12947
DomainEGF_dom

NELL1 SCUBE1 MEGF8

1.56e-0612373IPR024731
DomainJagged/Serrate

JAG2 JAG1

3.82e-062372IPR026219
DomainTSP_1

ADGRB3 PAPLN ADAMTS14 ADGRB1

7.14e-0663374PF00090
DomainTSP1

ADGRB3 PAPLN ADAMTS14 ADGRB1

8.09e-0665374SM00209
DomainTSP1_rpt

ADGRB3 PAPLN ADAMTS14 ADGRB1

8.09e-0665374IPR000884
DomainTSP1

ADGRB3 PAPLN ADAMTS14 ADGRB1

8.09e-0665374PS50092
DomainGPCR_2_brain_angio_inhib

ADGRB3 ADGRB1

1.14e-053372IPR008077
DomainDUF3454

NOTCH1 NOTCH3

1.14e-053372PF11936
DomainDUF3454_notch

NOTCH1 NOTCH3

1.14e-053372IPR024600
DomainDUF3454

NOTCH1 NOTCH3

1.14e-053372SM01334
DomaincEGF

SCUBE1 FBN1 EFEMP1

1.80e-0526373IPR026823
DomaincEGF

SCUBE1 FBN1 EFEMP1

1.80e-0526373PF12662
DomainNOD

NOTCH1 NOTCH3

2.29e-054372PF06816
DomainNotch

NOTCH1 NOTCH3

2.29e-054372IPR008297
DomainNODP

NOTCH1 NOTCH3

2.29e-054372PF07684
DomainNotch_NODP_dom

NOTCH1 NOTCH3

2.29e-054372IPR011656
DomainDSL

JAG2 JAG1

2.29e-054372PF01414
DomainNotch_NOD_dom

NOTCH1 NOTCH3

2.29e-054372IPR010660
DomainDSL

JAG2 JAG1

2.29e-054372SM00051
DomainNOD

NOTCH1 NOTCH3

2.29e-054372SM01338
DomainNODP

NOTCH1 NOTCH3

2.29e-054372SM01339
DomainEGF_LAM_2

LAMA5 MEGF8 AGRN

2.80e-0530373PS50027
DomainEGF_LAM_1

LAMA5 MEGF8 AGRN

2.80e-0530373PS01248
DomainLNR

NOTCH1 NOTCH3

3.80e-055372PS50258
DomainDSL

JAG2 JAG1

3.80e-055372IPR001774
DomainDSL

JAG2 JAG1

3.80e-055372PS51051
DomainNotch_ligand_N

JAG2 JAG1

3.80e-055372IPR011651
DomainMNNL

JAG2 JAG1

3.80e-055372PF07657
DomainNotch_dom

NOTCH1 NOTCH3

7.97e-057372IPR000800
DomainNotch

NOTCH1 NOTCH3

7.97e-057372PF00066
DomainTB

LTBP2 FBN1

7.97e-057372PF00683
DomainNL

NOTCH1 NOTCH3

7.97e-057372SM00004
Domain-

LTBP2 FBN1

1.06e-0483723.90.290.10
DomainTB

LTBP2 FBN1

1.36e-049372PS51364
DomainTB_dom

LTBP2 FBN1

1.36e-049372IPR017878
DomainCUB

ADGRB3 SCUBE1 MEGF8

1.57e-0453373PS01180
DomainCUB_dom

ADGRB3 SCUBE1 MEGF8

1.95e-0457373IPR000859
DomainLaminin_G_1

EYS AGRN

2.08e-0411372PF00054
DomainEphrin_rec_like

SCUBE1 SVEP1

2.08e-0411372PF07699
DomainGAIN_dom_N

ADGRB3 ADGRB1

2.08e-0411372IPR032471
DomainGAIN

ADGRB3 ADGRB1

2.08e-0411372PF16489
DomainVWFD

ZAN VWDE

4.50e-0416372PS51233
DomainVWD

ZAN VWDE

4.50e-0416372SM00216
DomainVWF_type-D

ZAN VWDE

4.50e-0416372IPR001846
DomainVWD

ZAN VWDE

4.50e-0416372PF00094
DomainPLAC

PAPLN ADAMTS14

6.39e-0419372IPR010909
DomainPLAC

PAPLN ADAMTS14

6.39e-0419372PS50900
DomainADAM_spacer1

PAPLN ADAMTS14

9.41e-0423372IPR010294
DomainADAM_spacer1

PAPLN ADAMTS14

9.41e-0423372PF05986
DomainPeptidase_M12B_ADAM-TS

PAPLN ADAMTS14

1.03e-0324372IPR013273
DomainEphrin_rec_like

SCUBE1 SVEP1

1.11e-0325372SM01411
DomainTyr-kin_ephrin_A/B_rcpt-like

SCUBE1 SVEP1

1.11e-0325372IPR011641
DomainHormR

ADGRB3 ADGRB1

1.11e-0325372SM00008
DomainHRM

ADGRB3 ADGRB1

1.40e-0328372PF02793
PathwayKEGG_MEDICUS_REFERENCE_NOTCH_SIGNALING_PATHWAY

JAG2 NOTCH1 JAG1 NOTCH3

6.43e-0913264M47423
PathwayWP_CANONICAL_AND_NONCANONICAL_NOTCH_SIGNALING

JAG2 NOTCH1 JAG1 NOTCH3

1.55e-0727264M39545
PathwayREACTOME_SIGNALING_BY_NOTCH1_T_7_9_NOTCH1_M1580_K2555_TRANSLOCATION_MUTANT

JAG2 NOTCH1 JAG1

1.94e-077263M27199
PathwayREACTOME_SIGNALING_BY_NOTCH

JAG2 NOTCH1 JAG1 NOTCH3

7.16e-0739264MM14604
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

LAMA5 SCUBE1 LTBP2 FBN1 EFEMP1 ADAMTS14 AGRN

8.57e-07300267M610
PathwayKEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00380

NOTCH1 JAG1 NOTCH3

1.21e-0612263M47532
PathwayWP_NOTCH_SIGNALING_WP268

JAG2 NOTCH1 JAG1 NOTCH3

1.29e-0645264M39571
PathwayWP_NOTCH_SIGNALING_PATHWAY

JAG2 NOTCH1 JAG1 NOTCH3

1.41e-0646264MM15971
PathwayKEGG_NOTCH_SIGNALING_PATHWAY

JAG2 NOTCH1 JAG1 NOTCH3

1.54e-0647264M7946
PathwayREACTOME_SIGNALING_BY_NOTCH3

JAG2 NOTCH1 JAG1 NOTCH3

1.82e-0649264M618
PathwayREACTOME_SIGNALING_BY_NOTCH1_HD_DOMAIN_MUTANTS_IN_CANCER

JAG2 NOTCH1 JAG1

2.50e-0615263M27202
PathwayKEGG_MEDICUS_VARIANT_NOTCH_OVEREXPRESSION_TO_NOTCH_SIGNALING_PATHWAY

JAG2 NOTCH1 JAG1

3.07e-0616263M47424
PathwayWP_NOTCH1_REGULATION_OF_ENDOTHELIAL_CELL_CALCIFICATION

JAG2 NOTCH1 JAG1

3.72e-0617263M39389
PathwayPID_NOTCH_PATHWAY

JAG2 NOTCH1 JAG1 NOTCH3

3.86e-0659264M17
PathwayWP_NOTCH_SIGNALING_WP61

JAG2 NOTCH1 JAG1 NOTCH3

4.42e-0661264M39540
PathwayREACTOME_SIGNALING_BY_NOTCH3

JAG2 JAG1 NOTCH3

5.29e-0619263MM15594
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

SCUBE1 LTBP2 FBN1 ADAMTS14 MEGF6 AGRN

6.00e-06258266MM14572
PathwayWP_PRIMARY_FOCAL_SEGMENTAL_GLOMERULOSCLEROSIS_FSGS

LAMA5 AGRN NOTCH1 JAG1

8.59e-0672264M39403
PathwayWP_PRIMARY_FOCAL_SEGMENTAL_GLOMERULOSCLEROSIS_FSGS

LAMA5 AGRN NOTCH1 JAG1

9.08e-0673264MM15906
PathwayREACTOME_NOTCH3_ACTIVATION_AND_TRANSMISSION_OF_SIGNAL_TO_THE_NUCLEUS

JAG2 JAG1 NOTCH3

1.25e-0525263M27879
PathwayWP_DELTANOTCH_SIGNALING_PATHWAY

JAG2 NOTCH1 JAG1 NOTCH3

1.44e-0582264MM15922
PathwayREACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS

JAG2 NOTCH1 JAG1

2.42e-0531263M592
PathwayREACTOME_DEFECTIVE_LFNG_CAUSES_SCDO3

NOTCH1 NOTCH3

3.26e-055262M27411
PathwayREACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI

NOTCH1 NOTCH3

3.26e-055262MM14733
PathwayWP_NEOVASCULARIZATION_PROCESSES

NOTCH1 JAG1 NOTCH3

4.15e-0537263M39506
PathwayREACTOME_MOLECULES_ASSOCIATED_WITH_ELASTIC_FIBRES

LTBP2 FBN1 EFEMP1

4.15e-0537263M27134
PathwayREACTOME_PRE_NOTCH_PROCESSING_IN_THE_ENDOPLASMIC_RETICULUM

NOTCH1 NOTCH3

4.88e-056262M27068
PathwayWP_OSTEOBLAST_DIFFERENTIATION_AND_RELATED_DISEASES

JAG2 NOTCH1 JAG1 NOTCH3

6.05e-05118264M39852
PathwayREACTOME_PRE_NOTCH_EXPRESSION_AND_PROCESSING

NOTCH1 NOTCH3

6.83e-057262MM14734
PathwayREACTOME_ELASTIC_FIBRE_FORMATION

LTBP2 FBN1 EFEMP1

7.02e-0544263M26969
PathwayKEGG_MEDICUS_REFERENCE_NOTCH_LIGAND_UBIQUITYLATION

JAG2 JAG1

1.17e-049262M47866
PathwayREACTOME_DISEASES_OF_GLYCOSYLATION

ADAMTS14 AGRN NOTCH1 NOTCH3

1.28e-04143264M27275
PathwayREACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS

JAG2 NOTCH1

1.46e-0410262MM14849
PathwayWP_NEUROGENESIS_REGULATION_IN_THE_OLFACTORY_EPITHELIUM

AGRN NOTCH1 JAG1

1.53e-0457263M48326
PathwayREACTOME_SIGNALING_BY_NOTCH1_PEST_DOMAIN_MUTANTS_IN_CANCER

JAG2 NOTCH1 JAG1

1.61e-0458263M29616
PathwayKEGG_MEDICUS_REFERENCE_NOTCH_PROTEOLYTIC_ACTIVATION

NOTCH1 NOTCH3

1.78e-0411262M47865
PathwayWP_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_IN_COLORECTAL_CANCER

JAG2 NOTCH1 JAG1 NOTCH3

2.01e-04161264M39770
PathwayKEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00381

NOTCH1 NOTCH3

2.13e-0412262M47533
PathwayKEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00382

NOTCH1 NOTCH3

2.52e-0413262M47534
PathwayREACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS

ADAMTS14 NOTCH1 NOTCH3

2.58e-0468263M27303
PathwayWP_CANCER_PATHWAYS

JAG2 LAMA5 TRAF4 NOTCH1 JAG1 NOTCH3

2.62e-04507266M48302
PathwayREACTOME_RUNX3_REGULATES_NOTCH_SIGNALING

NOTCH1 JAG1

2.94e-0414262M27808
PathwayREACTOME_SIGNALING_BY_NOTCH1

JAG2 NOTCH1 JAG1

3.31e-0474263M616
PathwayWP_AMPLIFICATION_AND_EXPANSION_OF_ONCOGENIC_PATHWAYS_AS_METASTATIC_TRAITS

NOTCH1 JAG1

4.37e-0417262M39443
PathwayREACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI

NOTCH1 NOTCH3

4.91e-0418262M614
PathwayREACTOME_SIGNALING_BY_NOTCH1

JAG2 NOTCH1

4.91e-0418262MM14775
PathwayWP_P53_TRANSCRIPTIONAL_GENE_NETWORK

TRAF4 NOTCH1 ADGRB1

7.10e-0496263M40062
PathwayREACTOME_NOTCH2_ACTIVATION_AND_TRANSMISSION_OF_SIGNAL_TO_THE_NUCLEUS

JAG2 JAG1

7.39e-0422262M27210
PathwayREACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY

NOTCH1 NOTCH3

8.08e-0423262MM14954
PathwayKEGG_DORSO_VENTRAL_AXIS_FORMATION

NOTCH1 NOTCH3

8.81e-0424262M11190
PathwayREACTOME_NOTCH3_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION

NOTCH1 NOTCH3

9.56e-0425262M27880
PathwayWP_HYPOTHESIZED_PATHWAYS_IN_PATHOGENESIS_OF_CARDIOVASCULAR_DISEASE

LTBP2 FBN1

9.56e-0425262M39713
PathwayREACTOME_SIGNALING_BY_NOTCH

JAG2 NOTCH1 JAG1 NOTCH3

1.00e-03246264M10189
PathwayREACTOME_DISEASES_OF_METABOLISM

ADAMTS14 AGRN NOTCH1 NOTCH3

1.06e-03250264M27554
PathwayREACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY

NOTCH1 NOTCH3

1.20e-0328262M6177
PathwayREACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_TRANSPORT_AND_UPTAKE_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS

FBN1 MEGF6 IGFBP6

1.36e-03120263MM14982
PathwayREACTOME_MOLECULES_ASSOCIATED_WITH_ELASTIC_FIBRES

LTBP2 FBN1

1.57e-0332262MM14854
PathwayREACTOME_SIGNALING_BY_NOTCH2

JAG2 JAG1

1.67e-0333262M604
PathwayWP_OSX_AND_MIRNAS_IN_TOOTH_DEVELOPMENT

NOTCH1 NOTCH3

1.77e-0334262M39390
PathwayREACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX

LAMA5 SCUBE1 FBN1

2.11e-03140263M587
PathwayREACTOME_TGF_BETA_RECEPTOR_SIGNALING_ACTIVATES_SMADS

LTBP2 FBN1

2.21e-0338262MM14874
PathwayREACTOME_ELASTIC_FIBRE_FORMATION

LTBP2 FBN1

2.32e-0339262MM14601
PathwayKEGG_FATTY_ACID_METABOLISM

ADH5 CPT1B

2.69e-0342262M699
PathwayWP_BREAST_CANCER_PATHWAY

JAG2 NOTCH1 NOTCH3

2.76e-03154263M39739
PathwayREACTOME_TGF_BETA_RECEPTOR_SIGNALING_ACTIVATES_SMADS

LTBP2 FBN1

3.36e-0347262M646
PathwayPID_TAP63_PATHWAY

TRAF4 JAG1

4.41e-0354262M256
PathwayWP_MARKERS_OF_KIDNEY_CELL_LINEAGE

NOTCH1 JAG1

5.25e-0359262M46460
PathwayREACTOME_NON_INTEGRIN_MEMBRANE_ECM_INTERACTIONS

LAMA5 AGRN

5.25e-0359262M27218
PathwayPID_INTEGRIN1_PATHWAY

LAMA5 FBN1

6.53e-0366262M18
PathwayREACTOME_ECM_PROTEOGLYCANS

LAMA5 AGRN

8.57e-0376262M27219
PathwayREACTOME_SIGNALING_BY_TGF_BETA_RECEPTOR_COMPLEX

LTBP2 FBN1

8.79e-0377262MM14670
PathwayREACTOME_SIGNALING_BY_NOTCH4

NOTCH1 JAG1

9.92e-0382262M594
PathwayKEGG_SMALL_CELL_LUNG_CANCER

LAMA5 TRAF4

1.04e-0284262M3228
PathwayKEGG_ECM_RECEPTOR_INTERACTION

LAMA5 AGRN

1.04e-0284262M7098
Pubmed

Comparison of an expanded ataxia interactome with patient medical records reveals a relationship between macular degeneration and ataxia.

JAG2 NELL1 FBN1 EFEMP1 MEGF6 MEGF8 AGRN NOTCH1

6.20e-1311838821078624
Pubmed

Activation of Notch signaling in human tongue carcinoma.

JAG2 NOTCH1 JAG1 NOTCH3

1.21e-12438420819128
Pubmed

Detection of Notch signaling molecules in cemento-ossifying fibroma of the jaws.

JAG2 NOTCH1 JAG1 NOTCH3

1.21e-12438420040020
Pubmed

Physical interaction of Delta1, Jagged1, and Jagged2 with Notch1 and Notch3 receptors.

JAG2 NOTCH1 JAG1 NOTCH3

6.05e-12538411006133
Pubmed

Functional diversity of notch family genes in fetal lung development.

JAG2 NOTCH1 JAG1 NOTCH3

6.05e-12538415064243
Pubmed

Protein interactome reveals converging molecular pathways among autism disorders.

JAG2 LAMA5 NELL1 FBN1 EFEMP1 MEGF6 IGFBP6 MEGF8 AGRN NOTCH1 NOTCH3

1.39e-11560381121653829
Pubmed

Expression pattern of notch1, 2 and 3 and Jagged1 and 2 in lymphoid and stromal thymus components: distinct ligand-receptor interactions in intrathymic T cell development.

JAG2 NOTCH1 JAG1 NOTCH3

4.23e-11738410383933
Pubmed

Human ligands of the Notch receptor.

JAG2 NOTCH1 JAG1 NOTCH3

4.23e-11738410079256
Pubmed

The distribution of Notch receptors and their ligands during articular cartilage development.

JAG2 NOTCH1 JAG1 NOTCH3

4.23e-11738412846471
Pubmed

P4 down-regulates Jagged2 and Notch1 expression during primordial folliculogenesis.

JAG2 NOTCH1 JAG1 NOTCH3

8.45e-11838422652674
Pubmed

Distinct expression patterns of notch family receptors and ligands during development of the mammalian inner ear.

JAG2 NOTCH1 JAG1 NOTCH3

8.45e-1183849858718
Pubmed

Notch/Delta expression in the developing mouse lung.

JAG2 NOTCH1 JAG1 NOTCH3

8.45e-11838411044610
Pubmed

Dynamic expression patterns of the pudgy/spondylocostal dysostosis gene Dll3 in the developing nervous system.

JAG2 NOTCH1 JAG1 NOTCH3

1.52e-10938411118901
Pubmed

Notch1 signals through Jagged2 to regulate apoptosis in the apical ectodermal ridge of the developing limb bud.

JAG2 NOTCH1 JAG1 NOTCH3

1.52e-10938416245338
Pubmed

Spatiotemporal expression of Notch receptors and ligands in developing mouse placenta.

JAG2 NOTCH1 JAG1 NOTCH3

2.53e-101038423665443
Pubmed

Localisation of members of the notch system and the differentiation of vibrissa hair follicles: receptors, ligands, and fringe modulators.

JAG2 NOTCH1 JAG1 NOTCH3

3.97e-101138410878608
Pubmed

Notch-associated gene expression in embryonic and adult taste papillae and taste buds suggests a role in taste cell lineage decisions.

JAG2 NOTCH1 JAG1 NOTCH3

3.97e-101138412866128
Pubmed

The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.

LAMA5 PAPLN LTBP2 FBN1 EFEMP1 IGFBP6 AGRN

5.77e-1016738722159717
Pubmed

Developmental expression of the Notch signaling pathway genes during mouse preimplantation development.

JAG2 NOTCH1 JAG1 NOTCH3

5.96e-101238415465494
Pubmed

Jagged1 is Essential for Radial Glial Maintenance in the Cortical Proliferative Zone.

JAG2 NOTCH1 JAG1 NOTCH3

8.60e-101338431202705
Pubmed

Vascular expression of Notch pathway receptors and ligands is restricted to arterial vessels.

JAG2 NOTCH1 JAG1 NOTCH3

8.60e-101338411578869
Pubmed

Molecular Profiling of the Developing Lacrimal Gland Reveals Putative Role of Notch Signaling in Branching Morphogenesis.

JAG2 NOTCH1 JAG1 NOTCH3

1.20e-091438428192800
Pubmed

Math1 controls cerebellar granule cell differentiation by regulating multiple components of the Notch signaling pathway.

JAG2 NOTCH1 JAG1 NOTCH3

1.20e-091438414757642
Pubmed

Expression of Notch pathway genes in the embryonic mouse metanephros suggests a role in proximal tubule development.

JAG2 NOTCH1 JAG1 NOTCH3

1.64e-091538412971992
Pubmed

Lunatic fringe, FGF, and BMP regulate the Notch pathway during epithelial morphogenesis of teeth.

JAG2 NOTCH1 JAG1 NOTCH3

1.64e-091538412167404
Pubmed

COUP-TFI controls Notch regulation of hair cell and support cell differentiation.

JAG2 NOTCH1 JAG1 NOTCH3

1.64e-091538416914494
Pubmed

Expression of Notch pathway components in fetal and adult mouse small intestine.

JAG2 NOTCH1 JAG1 NOTCH3

2.18e-091638412617809
Pubmed

Notch gene expression during pancreatic organogenesis.

JAG2 NOTCH1 JAG1 NOTCH3

2.18e-091638410842072
Pubmed

An essential role for Notch in neural crest during cardiovascular development and smooth muscle differentiation.

JAG2 NOTCH1 JAG1 NOTCH3

2.18e-091638417273555
Pubmed

The Cellular Prion Protein Controls Notch Signaling in Neural Stem/Progenitor Cells.

JAG2 NOTCH1 JAG1 NOTCH3

2.18e-091638427641601
Pubmed

Notch Dosage: Jagged1 Haploinsufficiency Is Associated With Reduced Neuronal Division and Disruption of Periglomerular Interneurons in Mice.

JAG2 NOTCH1 JAG1 NOTCH3

2.18e-091638432161758
Pubmed

Gamma-secretase activation of notch signaling regulates the balance of proximal and distal fates in progenitor cells of the developing lung.

JAG2 NOTCH1 JAG1 NOTCH3

2.85e-091738418694942
Pubmed

Segmental expression of Notch and Hairy genes in nephrogenesis.

JAG2 NOTCH1 JAG1 NOTCH3

2.85e-091738415821257
Pubmed

Developmental coronary maturation is disturbed by aberrant cardiac vascular endothelial growth factor expression and Notch signalling.

JAG2 NOTCH1 JAG1 NOTCH3

3.67e-091838418093989
Pubmed

RBPjkappa-dependent Notch function regulates Gata2 and is essential for the formation of intra-embryonic hematopoietic cells.

JAG2 NOTCH1 JAG1 NOTCH3

3.67e-091838415689374
Pubmed

Notch 2 and Notch 1/3 segregate to neuronal and glial lineages of the developing olfactory epithelium.

JAG2 NOTCH1 JAG1 NOTCH3

4.64e-091938416518823
Pubmed

A mutation in the Lunatic fringe gene suppresses the effects of a Jagged2 mutation on inner hair cell development in the cochlea.

JAG2 NOTCH1 JAG1

4.81e-09438310837254
Pubmed

Mouse jagged1 physically interacts with notch2 and other notch receptors. Assessment by quantitative methods.

NOTCH1 JAG1 NOTCH3

4.81e-09438310551863
Pubmed

Isolation and functional analysis of a cDNA for human Jagged2, a gene encoding a ligand for the Notch1 receptor.

JAG2 NOTCH1 JAG1

4.81e-0943839315665
Pubmed

The Notch signalling pathway in hair growth.

JAG2 NOTCH1 JAG1

4.81e-0943839858728
Pubmed

Notch pathway regulates female germ cell meiosis progression and early oogenesis events in fetal mouse.

JAG2 NOTCH1 JAG1

4.81e-09438324398584
Pubmed

Evolution of Cortical Neurogenesis in Amniotes Controlled by Robo Signaling Levels.

JAG2 NOTCH1 JAG1 SLIT3

5.79e-092038429961574
Pubmed

Neurovascular EGFL7 regulates adult neurogenesis in the subventricular zone and thereby affects olfactory perception.

JAG2 NOTCH1 JAG1 NOTCH3

7.15e-092138428656980
Pubmed

Conversion of biliary system to pancreatic tissue in Hes1-deficient mice.

JAG2 NOTCH1 JAG1 NOTCH3

7.15e-092138414702043
Pubmed

Endodermal Hedgehog signals modulate Notch pathway activity in the developing digestive tract mesenchyme.

JAG2 NOTCH1 JAG1 NOTCH3

8.73e-092238421750033
Pubmed

Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.

LTBP2 FBN1 EFEMP1 IGFBP6 AGRN SVEP1 SLIT3

9.00e-0924838724006456
Pubmed

Notch promotes epithelial-mesenchymal transition during cardiac development and oncogenic transformation.

JAG2 NOTCH1 JAG1 NOTCH3

1.06e-082338414701881
Pubmed

Notch-3 and Notch-4 signaling rescue from apoptosis human B-ALL cells in contact with human bone marrow-derived mesenchymal stromal cells.

JAG2 JAG1 NOTCH3

1.20e-08538321602525
Pubmed

Functional redundancy of the Notch gene family during mouse embryogenesis: analysis of Notch gene expression in Notch3-deficient mice.

NOTCH1 JAG1 NOTCH3

1.20e-08538315882997
Pubmed

Notch1 and its ligands Delta-like and Jagged are expressed and active in distinct cell populations in the postnatal mouse brain.

JAG2 NOTCH1 JAG1

1.20e-08538312175503
Pubmed

Squamous odontogenic tumor of the mandible: a case report demonstrating immunoexpression of Notch1, 3, 4, Jagged1 and Delta1.

NOTCH1 JAG1 NOTCH3

1.20e-08538320554499
Pubmed

Rbpj regulates development of prosensory cells in the mammalian inner ear.

JAG2 NOTCH1 JAG1 NOTCH3

1.27e-082438421420948
Pubmed

Adamts18 modulates the development of the aortic arch and common carotid artery.

LAMA5 FBN1 JAG1 NOTCH3

1.78e-082638434189436
Pubmed

Notch signaling controls liver development by regulating biliary differentiation.

JAG2 NOTCH1 JAG1 NOTCH3

1.78e-082638419369401
Pubmed

A study on Notch signaling in human breast cancer.

NOTCH1 JAG1 NOTCH3

2.40e-08638317822320
Pubmed

Binding of Delta1, Jagged1, and Jagged2 to Notch2 rapidly induces cleavage, nuclear translocation, and hyperphosphorylation of Notch2.

JAG2 NOTCH1 JAG1

2.40e-08638310958687
Pubmed

Characterization of Notch receptor expression in the developing mammalian heart and liver.

NOTCH1 JAG1 NOTCH3

2.40e-08638312244553
Pubmed

Profiling immunohistochemical expression of NOTCH1-3, JAGGED1, cMET, and phospho-MAPK in 100 carcinomas of unknown primary.

NOTCH1 JAG1 NOTCH3

2.40e-08638322526456
Pubmed

Aberrant expression of Notch signaling molecules in patients with immune thrombocytopenic purpura.

NOTCH1 JAG1 NOTCH3

2.40e-08638319603167
Pubmed

Mouse Serrate-1 (Jagged-1): expression in the developing tooth is regulated by epithelial-mesenchymal interactions and fibroblast growth factor-4.

NOTCH1 JAG1 NOTCH3

2.40e-0863839108364
Pubmed

Repression of Sox9 by Jag1 is continuously required to suppress the default chondrogenic fate of vascular smooth muscle cells.

JAG2 NOTCH1 JAG1 NOTCH3

2.82e-082938425535917
Pubmed

Notch signaling in stomach epithelial stem cell homeostasis.

JAG2 NOTCH1 JAG1 NOTCH3

2.82e-082938421402740
Pubmed

Notch signaling regulates ovarian follicle formation and coordinates follicular growth.

JAG2 NOTCH1 JAG1 NOTCH3

3.25e-083038424552588
Pubmed

p63 regulates multiple signalling pathways required for ectodermal organogenesis and differentiation.

JAG2 NOTCH1 JAG1 NOTCH3

3.25e-083038416524929
Pubmed

pRb-mediated control of epithelial cell proliferation and Indian hedgehog expression in mouse intestinal development.

JAG2 NOTCH1 JAG1 NOTCH3

3.25e-083038417257418
Pubmed

Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.

LAMA5 LTBP2 FBN1 EFEMP1 MEGF6 AGRN

3.60e-0817538628071719
Pubmed

ESCRT-dependent control of craniofacial morphogenesis with concomitant perturbation of NOTCH signaling.

JAG2 NOTCH1 JAG1 NOTCH3

3.73e-083138437573008
Pubmed

ΔNp63 knockout mice reveal its indispensable role as a master regulator of epithelial development and differentiation.

LAMA5 NOTCH1 JAG1 NOTCH3

3.73e-083138422274697
Pubmed

Notch1 haploinsufficiency causes ascending aortic aneurysms in mice.

FBN1 NOTCH1 JAG1

4.20e-08738329093270
Pubmed

Impaired expression of Notch signaling genes in aged human skeletal muscle.

NOTCH1 JAG1 NOTCH3

4.20e-08738317301032
Pubmed

Differentiation of CD11c+ CX3CR1+ cells in the small intestine requires Notch signaling.

NOTCH1 JAG1 NOTCH3

4.20e-08738324711412
Pubmed

Evidence for a Notch1-mediated transition during olfactory ensheathing cell development.

JAG2 NOTCH1 JAG1

4.20e-08738327271278
Pubmed

Notch1 and 2 cooperate in limb ectoderm to receive an early Jagged2 signal regulating interdigital apoptosis.

JAG2 NOTCH1 NOTCH3

4.20e-08738316169548
Pubmed

Differential Notch signaling in the epicardium is required for cardiac inflow development and coronary vessel morphogenesis.

JAG2 NOTCH1 JAG1 NOTCH3

5.49e-083438421311046
Pubmed

Notch signaling regulates smooth muscle differentiation of epicardium-derived cells.

JAG2 NOTCH1 JAG1 NOTCH3

6.19e-083538421252157
Pubmed

Cranial neural crest ablation of Jagged1 recapitulates the craniofacial phenotype of Alagille syndrome patients.

NOTCH1 JAG1 NOTCH3

6.71e-08838322156581
Pubmed

Notch1 and Jagged1 expression by the developing pulmonary vasculature.

NOTCH1 JAG1 NOTCH3

6.71e-08838312242716
Pubmed

Expression of Hairy/Enhancer of Split genes, Hes1 and Hes5, during murine nephron morphogenesis.

NOTCH1 JAG1 NOTCH3

6.71e-08838315465493
Pubmed

Notch signaling in postnatal pituitary expansion: proliferation, progenitors, and cell specification.

JAG2 NOTCH1 JAG1 NOTCH3

7.79e-083738424673559
Pubmed

Proteomics characterization of extracellular space components in the human aorta.

LAMA5 LTBP2 FBN1 EFEMP1 AGRN

8.69e-0810138520551380
Pubmed

Identification of high-molecular-weight proteins with multiple EGF-like motifs by motif-trap screening.

MEGF6 MEGF8 SLIT3

1.01e-0793839693030
Pubmed

Microfibril-associated glycoprotein-2 interacts with fibrillin-1 and fibrillin-2 suggesting a role for MAGP-2 in elastic fiber assembly.

FBN1 MEGF6 JAG1

1.01e-07938312122015
Pubmed

Divergent vascular mechanisms downstream of Sry establish the arterial system in the XY gonad.

JAG2 NOTCH1 JAG1

1.01e-07938311944948
Pubmed

Notch signaling is essential for vascular morphogenesis in mice.

JAG2 NOTCH1 JAG1

1.01e-07938310837027
Pubmed

Foxp1/4 control epithelial cell fate during lung development and regeneration through regulation of anterior gradient 2.

JAG2 NOTCH1 JAG1 NOTCH3

1.19e-074138422675208
Pubmed

Patent ductus arteriosus in mice with smooth muscle-specific Jag1 deletion.

NOTCH1 JAG1 NOTCH3

1.44e-071038321068062
Pubmed

Dynamics of Notch pathway expression during mouse testis post-natal development and along the spermatogenic cycle.

NOTCH1 JAG1 NOTCH3

1.44e-071038324015274
Pubmed

A modifier in the 129S2/SvPasCrl genome is responsible for the viability of Notch1[12f/12f] mice.

NOTCH1 JAG1 NOTCH3

1.44e-071038331590629
Pubmed

The notch pathway positively regulates programmed cell death during erythroid differentiation.

JAG2 NOTCH1 JAG1 NOTCH3

1.59e-074438417476283
Pubmed

Jag2-Notch1 signaling regulates oral epithelial differentiation and palate development.

JAG2 NOTCH1 NOTCH3

1.97e-071138316607638
Pubmed

Coexpression of Cux-1 and Notch signaling pathway components during kidney development.

NOTCH1 JAG1 NOTCH3

1.97e-071138315499562
Pubmed

A family of mammalian Fringe genes implicated in boundary determination and the Notch pathway.

NOTCH1 JAG1 NOTCH3

1.97e-07113839187150
Pubmed

Deletion of hypoxia-inducible factor prolyl 4-hydroxylase 2 in FoxD1-lineage mesenchymal cells leads to congenital truncal alopecia.

JAG2 NOTCH1 JAG1 NOTCH3

2.28e-074838435247391
Pubmed

A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.

JAG2 NELL1 EFEMP1 MEGF6 IGFBP6 MEGF8 AGRN NOTCH1

2.57e-0760838816713569
Pubmed

Notch-mediated lateral induction is necessary to maintain vestibular prosensory identity during inner ear development.

NOTCH1 JAG1 NOTCH3

2.63e-071238332147304
Pubmed

Developmental regulation of Notch signaling genes in the embryonic pituitary: Prop1 deficiency affects Notch2 expression.

NOTCH1 JAG1 NOTCH3

2.63e-071238314732396
Pubmed

Inhibition of notch1-dependent cardiomyogenesis leads to a dilated myopathy in the neonatal heart.

NOTCH1 JAG1 NOTCH3

3.42e-071338320558824
Pubmed

The G4 resolvase RHAU regulates ventricular trabeculation and compaction through transcriptional and post-transcriptional mechanisms.

JAG2 NOTCH1 JAG1

3.42e-071338334838591
Pubmed

Canonical Notch signaling is not necessary for prosensory induction in the mouse cochlea: insights from a conditional mutant of RBPjkappa.

NOTCH1 JAG1 NOTCH3

3.42e-071338321632926
Pubmed

Impaired embryonic haematopoiesis yet normal arterial development in the absence of the Notch ligand Jagged1.

JAG2 NOTCH1 JAG1

4.34e-071438318528438
InteractionHOXA1 interactions

JAG2 VWC2L LAMA5 NELL1 TRAF4 FBN1 EFEMP1 MEGF6 MEGF8 AGRN NOTCH1 NOTCH3

1.38e-123563812int:HOXA1
InteractionMFAP5 interactions

JAG2 LAMA5 FBN1 MEGF6 VWDE JAG1 NOTCH3

5.94e-1252387int:MFAP5
InteractionNTN5 interactions

JAG2 FBN1 VWDE NOTCH1 NOTCH3

7.51e-1024385int:NTN5
InteractionATXN7 interactions

JAG2 NELL1 FBN1 EFEMP1 MEGF6 MEGF8 AGRN

1.22e-09109387int:ATXN7
InteractionCACNA1A interactions

JAG2 NELL1 EFEMP1 MEGF6 MEGF8 AGRN NOTCH1

2.86e-09123387int:CACNA1A
InteractionIGFL3 interactions

JAG2 LAMA5 AGRN VWDE NOTCH1 NOTCH3

5.44e-0975386int:IGFL3
InteractionGFI1B interactions

JAG2 NELL1 EFEMP1 MEGF6 MEGF8 AGRN NOTCH1

5.78e-09136387int:GFI1B
InteractionEDN3 interactions

JAG2 LAMA5 MEGF8 AGRN VWDE NOTCH1

4.94e-08108386int:EDN3
InteractionCFC1 interactions

LAMA5 PAPLN MEGF8 AGRN VWDE NOTCH1

1.24e-07126386int:CFC1
InteractionMBD1 interactions

JAG2 NELL1 MEGF6 NOTCH1 NOTCH3

3.25e-0777385int:MBD1
InteractionEGFL7 interactions

RASSF10 NELL1 EFEMP1 NOTCH1 NOTCH3

3.25e-0777385int:EGFL7
InteractionZNF74 interactions

JAG2 LTBP2 NOTCH1 NOTCH3

4.78e-0734384int:ZNF74
InteractionSIRPD interactions

JAG2 LAMA5 MEGF8 VWDE NOTCH1

5.65e-0786385int:SIRPD
InteractionELSPBP1 interactions

LAMA5 MEGF8 AGRN VWDE NOTCH1

7.92e-0792385int:ELSPBP1
InteractionFBXO2 interactions

JAG2 LAMA5 FBN1 MEGF8 AGRN NOTCH1 JAG1 NOTCH3

8.00e-07411388int:FBXO2
InteractionJAG1 interactions

JAG2 NOTCH1 JAG1 NOTCH3

1.03e-0641384int:JAG1
InteractionATN1 interactions

JAG2 NELL1 EFEMP1 MEGF6 MEGF8 AGRN

1.27e-06187386int:ATN1
InteractionMFAP2 interactions

JAG2 FBN1 JAG1

1.34e-0612383int:MFAP2
InteractionSDF2L1 interactions

JAG2 LAMA5 PAPLN EFEMP1 MEGF8 AGRN VWDE

2.05e-06322387int:SDF2L1
InteractionFBLN2 interactions

LAMA5 FBN1 EFEMP1 VWDE

7.12e-0666384int:FBLN2
InteractionPRG2 interactions

JAG2 LAMA5 ADAMTS14 VWDE NOTCH1 NOTCH3

1.43e-05285386int:PRG2
InteractionZNF707 interactions

LTBP2 NOTCH1 ZNF783 NOTCH3

1.46e-0579384int:ZNF707
InteractionMSTN interactions

JAG2 MEGF8 VWDE

3.25e-0533383int:MSTN
InteractionJAG2 interactions

JAG2 NOTCH1 JAG1 NOTCH3

5.38e-05110384int:JAG2
InteractionNOTCH3 interactions

JAG2 NOTCH1 JAG1 NOTCH3

5.97e-05113384int:NOTCH3
InteractionIGFBP4 interactions

MEGF8 VWDE NOTCH1

6.27e-0541383int:IGFBP4
InteractionZNF398 interactions

LTBP2 EFEMP1 ZNF783

7.25e-0543383int:ZNF398
InteractionPOFUT1 interactions

FBLN7 NOTCH1 JAG1

7.25e-0543383int:POFUT1
InteractionFBLN1 interactions

NELL1 EFEMP1 AGRN NOTCH3

9.99e-05129384int:FBLN1
InteractionNUFIP2 interactions

NELL1 LTBP2 EFEMP1 MEGF6 AGRN NOTCH3

1.19e-04417386int:NUFIP2
InteractionZNF408 interactions

LTBP2 FBN1 EFEMP1 NOTCH3

1.57e-04145384int:ZNF408
InteractionZFP41 interactions

FBN1 AGRN NOTCH3

1.69e-0457383int:ZFP41
InteractionLYPD1 interactions

JAG2 MEGF8 VWDE

1.78e-0458383int:LYPD1
InteractionZNF778 interactions

LTBP2 EFEMP1

1.88e-0411382int:ZNF778
InteractionOIT3 interactions

JAG2 LAMA5 VWDE

2.49e-0465383int:OIT3
InteractionFBN2 interactions

LTBP2 FBN1 SVEP1

2.49e-0465383int:FBN2
InteractionSHANK3 interactions

JAG2 EFEMP1 ZAN MEGF6 NOTCH1 NOTCH3

3.05e-04496386int:SHANK3
InteractionIGSF5 interactions

NOTCH1 NOTCH3

3.11e-0414382int:IGSF5
InteractionLGALS1 interactions

JAG2 LAMA5 NOTCH1 JAG1 NOTCH3

3.78e-04332385int:LGALS1
InteractionZNF260 interactions

NELL1 LTBP2

4.09e-0416382int:ZNF260
InteractionZNF628 interactions

LTBP2 EFEMP1

4.09e-0416382int:ZNF628
InteractionMAML2 interactions

NOTCH1 NOTCH3

4.62e-0417382int:MAML2
InteractionZNF358 interactions

LTBP2 EFEMP1

5.80e-0419382int:ZNF358
InteractionZNF791 interactions

LTBP2 EFEMP1

6.44e-0420382int:ZNF791
InteractionMAML3 interactions

NOTCH1 NOTCH3

6.44e-0420382int:MAML3
InteractionZNF627 interactions

LTBP2 EFEMP1

6.44e-0420382int:ZNF627
InteractionLTBP1 interactions

FBN1 EFEMP1 NOTCH3

6.92e-0492383int:LTBP1
InteractionCASR interactions

NOTCH1 NOTCH3

7.81e-0422382int:CASR
InteractionFBLN7 interactions

FBLN7 IGHA1

8.54e-0423382int:FBLN7
InteractionSNTA1 interactions

ADH5 ADGRB3 ADGRB1

1.02e-03105383int:SNTA1
InteractionZNF444 interactions

LAMA5 LTBP2 EFEMP1

1.04e-03106383int:ZNF444
InteractionADAM32 interactions

JAG2 NOTCH3

1.09e-0326382int:ADAM32
InteractionDNASE2 interactions

LAMA5 FBN1

1.09e-0326382int:DNASE2
InteractionNOTCH2 interactions

JAG2 NOTCH1 ZNF783 JAG1 NOTCH3

1.13e-03423385int:NOTCH2
InteractionMFNG interactions

NOTCH1 JAG1

1.18e-0327382int:MFNG
InteractionCXCL5 interactions

VWC2L VWDE

1.18e-0327382int:CXCL5
InteractionTRMT2B interactions

VWC2L NELL1

1.18e-0327382int:TRMT2B
InteractionTOP3B interactions

JAG2 LAMA5 PAPLN TRAF4 MEGF6 MEGF8 AGRN NOTCH1 NSD3

1.34e-031470389int:TOP3B
InteractionDNASE1L1 interactions

LAMA5 ADAMTS14 MEGF8

1.49e-03120383int:DNASE1L1
InteractionLLCFC1 interactions

LAMA5 AGRN VWDE

1.53e-03121383int:LLCFC1
InteractionLAMB2 interactions

LAMA5 NELL1 EFEMP1

1.56e-03122383int:LAMB2
InteractionALPP interactions

JAG2 IGFBP6 MEGF8

1.60e-03123383int:ALPP
InteractionLILRA5 interactions

JAG2 VWDE

1.66e-0332382int:LILRA5
InteractionIGHA1 interactions

FBLN7 IGHA1 AGRN

1.68e-03125383int:IGHA1
InteractionCBLN4 interactions

LAMA5 MEGF8 AGRN

1.75e-03127383int:CBLN4
Cytoband6q12

ADGRB3 EYS

1.53e-04223826q12
CytobandEnsembl 112 genes in cytogenetic band chr6q12

ADGRB3 EYS

2.14e-0426382chr6q12
GeneFamilyAdhesion G protein-coupled receptors, subfamily B

ADGRB3 ADGRB1

4.24e-063222912
GeneFamilyFibulins

FBLN7 EFEMP1

3.94e-058222556
GeneFamilyHyalectan proteoglycans|V-set domain containing|Sushi domain containing|C-type lectin domain containing

FBLN7 SVEP1

2.17e-03572221179
GeneFamilyAnkyrin repeat domain containing

NOTCH1 NOTCH3

3.46e-02242222403
CoexpressionNABA_ECM_GLYCOPROTEINS

LAMA5 NELL1 PAPLN FBLN7 LTBP2 FBN1 EFEMP1 IGFBP6 OTOGL AGRN VWDE SVEP1 SLIT3

4.99e-191913813MM17059
CoexpressionNABA_ECM_GLYCOPROTEINS

LAMA5 NELL1 PAPLN FBLN7 EYS LTBP2 FBN1 EFEMP1 IGFBP6 AGRN VWDE SVEP1 SLIT3

7.03e-191963813M3008
CoexpressionNABA_CORE_MATRISOME

LAMA5 NELL1 PAPLN FBLN7 LTBP2 FBN1 EFEMP1 IGFBP6 OTOGL AGRN VWDE SVEP1 SLIT3

4.74e-172703813MM17057
CoexpressionNABA_CORE_MATRISOME

LAMA5 NELL1 PAPLN FBLN7 EYS LTBP2 FBN1 EFEMP1 IGFBP6 AGRN VWDE SVEP1 SLIT3

6.02e-172753813M5884
CoexpressionNABA_MATRISOME

VWC2L LAMA5 NELL1 PAPLN FBLN7 SCUBE1 LTBP2 FBN1 EFEMP1 ADAMTS14 MEGF6 IGFBP6 MEGF8 OTOGL AGRN VWDE SVEP1 SLIT3

4.74e-1610083818MM17056
CoexpressionNABA_MATRISOME

VWC2L LAMA5 NELL1 PAPLN FBLN7 EYS SCUBE1 LTBP2 FBN1 EFEMP1 ADAMTS14 MEGF6 IGFBP6 MEGF8 AGRN VWDE SVEP1 SLIT3

6.44e-1610263818M5889
CoexpressionFUKUSHIMA_TNFSF11_TARGETS

JAG2 NOTCH1 JAG1 NOTCH3

6.75e-0916384M2207
CoexpressionFUKUSHIMA_TNFSF11_TARGETS

JAG2 NOTCH1 JAG1 NOTCH3

6.75e-0916384MM1296
CoexpressionNABA_MATRISOME_PRIMARY_METASTATIC_COLORECTAL_TUMOR

PAPLN LTBP2 MEGF8 AGRN SVEP1

2.30e-0859385M47989
CoexpressionHAY_BONE_MARROW_STROMAL

SCUBE1 LTBP2 FBN1 EFEMP1 IGFBP6 OTOGL SVEP1 JAG1 NOTCH3 SLIT3

9.77e-087673810M39209
CoexpressionBOQUEST_STEM_CELL_UP

LTBP2 FBN1 EFEMP1 IGFBP6 SVEP1 SLIT3

1.95e-06261386M1834
CoexpressionLU_TUMOR_ANGIOGENESIS_UP

JAG2 NOTCH1 JAG1

6.32e-0625383M9946
CoexpressionGAO_LARGE_INTESTINE_ADULT_CJ_IMMUNE_CELLS

ADGRB3 LAMA5 LTBP2 FBN1 EFEMP1 IGFBP6 NOTCH3

7.11e-06505387M39167
CoexpressionHALLMARK_NOTCH_SIGNALING

NOTCH1 JAG1 NOTCH3

1.35e-0532383M5903
CoexpressionNABA_BASEMENT_MEMBRANES

LAMA5 PAPLN AGRN

2.68e-0540383M5887
CoexpressionHALLMARK_WNT_BETA_CATENIN_SIGNALING

JAG2 NOTCH1 JAG1

3.10e-0542383M5895
CoexpressionHE_LIM_SUN_FETAL_LUNG_C0_VASCULAR_SMC_1_CELL

LTBP2 MEGF6 JAG1 NOTCH3

3.11e-05124384M45686
CoexpressionNABA_MATRISOME_INSULINOMA

FBN1 EFEMP1

4.28e-057382MM17050
CoexpressionVART_KSHV_INFECTION_ANGIOGENIC_MARKERS_DN

LAMA5 NOTCH1 NOTCH3 ADGRB1

4.34e-05135384M5825
CoexpressionBRUNEAU_HEART_GREAT_VESSELS_AND_VALVULOGENESIS

NOTCH1 JAG1

5.70e-058382M9884
CoexpressionSCIAN_CELL_CYCLE_TARGETS_OF_TP53_AND_TP73_UP

JAG2 LTBP2

7.32e-059382M18679
CoexpressionKOMMAGANI_TP63_GAMMA_TARGETS

JAG2 NOTCH3

7.32e-059382M9630
CoexpressionPETROVA_ENDOTHELIUM_LYMPHATIC_VS_BLOOD_DN

LAMA5 LTBP2 EFEMP1 AGRN

8.81e-05162384M1459
CoexpressionSASAKI_TARGETS_OF_TP73_AND_TP63

JAG2 JAG1

1.34e-0412382M17374
CoexpressionMIKKELSEN_NPC_HCP_WITH_H3K27ME3

JAG2 NELL1 SCUBE1 LTBP2 ADGRB1

1.35e-04345385M2009
CoexpressionMIKKELSEN_NPC_HCP_WITH_H3K27ME3

JAG2 NELL1 SCUBE1 LTBP2 ADGRB1

1.39e-04347385MM860
CoexpressionGSE6259_CD4_TCELL_VS_CD8_TCELL_UP

LAMA5 LTBP2 IGFBP6 SLIT3

1.53e-04187384M6738
CoexpressionHOSHIDA_LIVER_CANCER_SURVIVAL_UP

FBN1 IGFBP6 SLIT3

1.63e-0473383M6939
CoexpressionHE_LIM_SUN_FETAL_LUNG_C0_EARLY_MESOTHELIAL_CELL

LAMA5 PAPLN TRAF4 EFEMP1 AGRN C16orf87

1.79e-04584386M45668
CoexpressionBUSSLINGER_ESOPHAGEAL_QUIESCENT_BASAL_CELLS

JAG2 LAMA5 MEGF6

1.91e-0477383M40001
CoexpressionGSE46242_CTRL_VS_EGR2_DELETED_TH1_CD4_TCELL_UP

ADGRB3 IGFBP6 MEGF8 ADGRB1

1.94e-04199384M9705
CoexpressionGSE11961_MEMORY_BCELL_DAY7_VS_GERMINAL_CENTER_BCELL_DAY7_DN

EFEMP1 ZAN MEGF6 AGRN

1.98e-04200384M9370
CoexpressionWONG_ENDMETRIUM_CANCER_DN

FBN1 EFEMP1 IGFBP6

1.98e-0478383M1311
CoexpressionYOSHIMURA_MAPK8_TARGETS_DN

LAMA5 LTBP2 IGFBP6 JAG1 SLIT3

2.09e-04379385M1885
CoexpressionROSS_AML_WITH_PML_RARA_FUSION

MEGF6 AGRN JAG1

2.14e-0480383M15368
CoexpressionHU_FETAL_RETINA_FIBROBLAST

SCUBE1 FBN1 IGFBP6 JAG1 NOTCH3

2.24e-04385385M39264
CoexpressionPHONG_TNF_RESPONSE_VIA_P38_COMPLETE

TRAF4 AGRN NOTCH1 JAG1

3.05e-04224384M2500
CoexpressionTHUM_MIR21_TARGETS_HEART_DISEASE_UP

LTBP2 SVEP1

3.09e-0418382M13796
CoexpressionTHUM_MIR21_TARGETS_HEART_DISEASE_UP

LTBP2 SVEP1

3.09e-0418382MM1241
CoexpressionLINDGREN_BLADDER_CANCER_CLUSTER_3_DN

FBLN7 CPT1B NOTCH1 JAG1

3.16e-04226384M11238
CoexpressionMURARO_PANCREAS_MESENCHYMAL_STROMAL_CELL

ADH5 LTBP2 FBN1 NOTCH1 JAG1 NOTCH3

4.09e-04681386M39175
CoexpressionWOO_LIVER_CANCER_RECURRENCE_UP

JAG2 LAMA5 JAG1

4.76e-04105383M12602
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HNBGABA

ADGRB3 JAG2 NELL1 MEGF6 SCN2A ADGRB1

4.84e-04703386M39070
CoexpressionLIM_MAMMARY_LUMINAL_MATURE_UP

LAMA5 PGAP6 NSD3

5.75e-04112383MM1327
CoexpressionLIM_MAMMARY_LUMINAL_MATURE_UP

LAMA5 PGAP6 NSD3

5.90e-04113383M2578
CoexpressionLIM_MAMMARY_STEM_CELL_UP

FBLN7 IGFBP6 SVEP1 JAG1 SLIT3

6.09e-04479385M2573
CoexpressionHE_LIM_SUN_FETAL_LUNG_C3_GRIA2_POS_ARTERIAL_ENDO_CELL

JAG2 LAMA5 JAG1

6.21e-04115383M45752
CoexpressionLIM_MAMMARY_STEM_CELL_UP

FBLN7 IGFBP6 SVEP1 JAG1 SLIT3

6.33e-04483385MM1082
CoexpressionBLANCO_MELO_INFLUENZA_A_INFECTION_A594_CELLS_DN

RASSF10 MEGF6 NOTCH3

6.69e-04118383M34005
CoexpressionSHIN_B_CELL_LYMPHOMA_CLUSTER_7

TRAF4 NOTCH3

7.02e-0427382M1391
CoexpressionSHIN_B_CELL_LYMPHOMA_CLUSTER_7

TRAF4 NOTCH3

7.02e-0427382MM1135
CoexpressionGSE5589_WT_VS_IL10_KO_LPS_AND_IL10_STIM_MACROPHAGE_180MIN_DN

ADGRB3 IGFBP6 SCN2A

7.37e-04122383M6677
CoexpressionHE_LIM_SUN_FETAL_LUNG_C3_ARTERIAL_ENDOTHELIAL_CELL

JAG2 LAMA5 FBN1 JAG1

7.65e-04286384M45746
CoexpressionMEISSNER_BRAIN_HCP_WITH_H3K4ME3_AND_H3K27ME3

RASSF10 NELL1 FBLN7 SCUBE1 SVEP1 NOTCH1 JAG1

7.88e-041074387M1941
CoexpressionRUBENSTEIN_SKELETAL_MUSCLE_FBN1_FAP_CELLS

FBN1 EFEMP1 IGFBP6 JAG1

7.95e-04289384M41750
CoexpressionNABA_MATRISOME_METASTATIC_LUNG_LYMPH_NODE_METASTASIS

LTBP2 AGRN

8.11e-0429382MM17055
CoexpressionNABA_MATRISOME_METASTATIC_COLORECTAL_LIVER_METASTASIS

LTBP2 AGRN

8.68e-0430382M47990
CoexpressionTRAVAGLINI_LUNG_ADVENTITIAL_FIBROBLAST_CELL

FBN1 EFEMP1 IGFBP6 SVEP1

8.69e-04296384M41675
CoexpressionPETRETTO_CARDIAC_HYPERTROPHY

FBN1 EFEMP1

1.12e-0334382M14043
CoexpressionLIU_CDX2_TARGETS_UP

JAG1 NOTCH3

1.18e-0335382M16637
CoexpressionNABA_MATRISOME_PRIMARY_METASTATIC_LUNG_TUMOR

LTBP2 AGRN

1.18e-0335382MM17054
CoexpressionCLASPER_LYMPHATIC_VESSELS_DURING_METASTASIS_DN

LTBP2 FBN1

1.18e-0335382M11788
CoexpressionGSE10500_ARTHRITIC_SYNOVIAL_FLUID_VS_HEALTHY_MACROPHAGE_DN

ADGRB3 ZAN NOTCH1

1.21e-03145383M359
CoexpressionDESCARTES_FETAL_KIDNEY_STROMAL_CELLS

LTBP2 FBN1 IGFBP6

1.24e-03146383M40222
CoexpressionCLASPER_LYMPHATIC_VESSELS_DURING_METASTASIS_DN

LTBP2 FBN1

1.25e-0336382MM1212
CoexpressionHALLMARK_ANGIOGENESIS

JAG2 JAG1

1.25e-0336382M5944
CoexpressionAtlasStromal Cells, St.31-38-44-.SLN, CD45- gp38- CD31- CD44-, Lymph Node, avg-2

LAMA5 FBN1 EFEMP1 IGFBP6 SVEP1 JAG1 NOTCH3 SLIT3

9.05e-07453378GSM777067_500
CoexpressionAtlasStromal Cells, FRC.SLN, gp38+ CD31- CD140a+, Lymph Node, avg-4

LTBP2 FBN1 EFEMP1 SVEP1 JAG1 NOTCH3 SLIT3

1.17e-05455377GSM777055_500
CoexpressionAtlasStromal Cells, FRC.MLN, gp38+ CD31- CD140a+, Lymph Node, avg-5

LAMA5 FBN1 EFEMP1 IGFBP6 SVEP1 NOTCH3 SLIT3

1.36e-05466377GSM777050_500
CoexpressionAtlasStromal Cells, Fi.Sk, gp38+ CD140a+, Skin, avg-4

FBN1 EFEMP1 IGFBP6 SLIT3

2.41e-0597374GSM777046_100
CoexpressionAtlasdev gonad_e11.5_M_GonadVasMes_Flk_k-means-cluster#4_top-relative-expression-ranked_500

SCUBE1 FBN1 EFEMP1 SVEP1 SCN2A

2.84e-05207375gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_k4_500
CoexpressionAtlaskidney_adult_RenalCapsule_k-means-cluster#2_top-relative-expression-ranked_1000

LTBP2 FBN1 EFEMP1 IGFBP6 SVEP1 SCN2A

3.90e-05369376gudmap_kidney_adult_RenalCapsule_k2_1000
CoexpressionAtlasMesoderm Day 30_vs_Mesoderm Day 15-Confounder_removed-fold2.0_adjp0.05

LTBP2 FBN1 EFEMP1

4.60e-0540373PCBC_ratio_MESO-30_vs_MESO-15_cfr-2X-p05
CoexpressionAtlaskidney_adult_RenalCapsule_k-means-cluster#1_top-relative-expression-ranked_500

FBN1 EFEMP1 IGFBP6 SVEP1 SCN2A

5.74e-05240375gudmap_kidney_adult_RenalCapsule_k1_500
CoexpressionAtlasMesoderm Day 5-reprogram_OSKM-L_vs_Mesoderm Day 5-reprogram_NA-Confounder_removed-fold2.0_adjp0.05

LAMA5 PAPLN AGRN NOTCH1 NOTCH3

1.21e-04281375PCBC_ratio_MESO-5_from-OSKM-L_vs_MESO-5_from-ESC_cfr-2X-p05
CoexpressionAtlasMesoderm Day 5-method_mRNA_vs_Mesoderm Day 5-method_NA-Confounder_removed-fold2.0_adjp0.05

LAMA5 PAPLN AGRN NOTCH1 NOTCH3

1.21e-04281375PCBC_ratio_MESO-5_from-mRNA_vs_MESO-5_from-ESC_cfr-2X-p05
CoexpressionAtlaskidney_P0_JuxtaGlom_Ren1_top-relative-expression-ranked_500

LAMA5 FBN1 EFEMP1 JAG1 NOTCH3 SLIT3

1.25e-04456376gudmap_kidney_P0_JuxtaGlom_Ren1_500
CoexpressionAtlasJC_fibro_top-relative-expression-ranked_1000_k-means-cluster#1

LTBP2 FBN1 EFEMP1 IGFBP6 SVEP1 SLIT3

1.38e-04464376JC_fibro_1000_K1
CoexpressionAtlaskidney_P0_JuxtaGlom_Ren1_k-means-cluster#3_top-relative-expression-ranked_1000

LAMA5 AGRN JAG1 NOTCH3 SLIT3

1.47e-04293375gudmap_kidney_P0_JuxtaGlom_Ren1_k3_1000
CoexpressionAtlaskidney_P0_JuxtaGlom_Ren1_k-means-cluster#4_top-relative-expression-ranked_500

LAMA5 JAG1 NOTCH3 SLIT3

1.50e-04155374gudmap_kidney_P0_JuxtaGlom_Ren1_k4_500
CoexpressionAtlasAravindRamakr_EmbryoidBody-LF_top-relative-expression-ranked_2500_k-means-cluster#2

NELL1 SCUBE1 LTBP2 FBN1 ADAMTS14 IGFBP6 SVEP1 SLIT3

1.90e-04951378Arv_EB-LF_2500_K2
CoexpressionAtlasProgenitor-Cell-Biology-Consortium_reference_CardiacMyocyte_top-relative-expression-ranked_500

LTBP2 FBN1 EFEMP1 ADAMTS14 IGFBP6 SVEP1

1.92e-04493376PCBC_ctl_CardiacMyocyte_500
CoexpressionAtlasJC_fibro_top-relative-expression-ranked_500

FBN1 EFEMP1 MEGF6 IGFBP6 SVEP1 SLIT3

1.94e-04494376JC_fibro_500
CoexpressionAtlasdev lower uro neuro_e15.5_PelvicGanglion_Sox10_top-relative-expression-ranked_1000

ADGRB3 NELL1 FBN1 EFEMP1 SVEP1 SCN2A SLIT3

2.39e-04734377gudmap_dev lower uro neuro_e15.5_PelvicGanglion_Sox10_1000
CoexpressionAtlaskidney_adult_JuxtaGlom_Ren1_Captopr_k-means-cluster#4_top-relative-expression-ranked_1000

JAG1 NOTCH3 NSD3 SLIT3

2.60e-04179374gudmap_kidney_adult_JuxtaGlom_Ren1_Captopr_k4_1000
CoexpressionAtlasdev gonad_e11.5_M_GonadVasMes_Flk_k-means-cluster#1_top-relative-expression-ranked_1000

SCUBE1 FBN1 EFEMP1 SVEP1 SCN2A

2.81e-04337375gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_k1_1000
CoexpressionAtlaskidney_adult_JuxtaGlom_Ren1_Captopr_top-relative-expression-ranked_1000

EFEMP1 PGAP6 SCN2A JAG1 NOTCH3 NSD3 SLIT3

3.40e-04778377gudmap_kidney_adult_JuxtaGlom_Ren1_Captopr_1000
CoexpressionAtlasDevelopingGonad_e18.5_epididymis_emap-13166_top-relative-expression-ranked_1000

ADGRB3 LTBP2 EFEMP1 MEGF6 IGFBP6 NSD3 SLIT3

3.99e-04799377gudmap_developingGonad_e18.5_epididymis_1000
CoexpressionAtlasdev lower uro neuro_e15.5_PelvicGanglion_Sox10_top-relative-expression-ranked_500

ADGRB3 FBN1 EFEMP1 SCN2A SLIT3

4.36e-04371375gudmap_dev lower uro neuro_e15.5_PelvicGanglion_Sox10_500
CoexpressionAtlasEctoderm Differentiated Cells_vs_Endoderm Differentiated Cells-Confounder_removed-fold2.0_adjp0.05

LAMA5 FBLN7 SCUBE1 LTBP2 FBN1 EFEMP1 AGRN JAG1

4.37e-041075378PCBC_ratio_ECTO_vs_DE_cfr-2X-p05
CoexpressionAtlasJC_fibro_top-relative-expression-ranked_500_k-means-cluster#3

FBN1 IGFBP6 SVEP1 SLIT3

4.42e-04206374JC_fibro_500_K3
CoexpressionAtlasratio_EmbryoidBody_vs_StemCell_top-relative-expression-ranked_2500_k-means-cluster#3

ADGRB3 NELL1 FBLN7 SCUBE1 LTBP2 FBN1 SVEP1 SLIT3

4.91e-041094378ratio_EB_vs_SC_2500_K3
CoexpressionAtlasDevelopingKidney_e15.5_S-shaped body_emap-27855_top-relative-expression-ranked_500

RASSF10 PGAP6 AGRN NOTCH1 JAG1

6.57e-04406375gudmap_developingKidney_e15.5_S-shaped body_500
CoexpressionAtlaskidney_adult_RenalCapsule_top-relative-expression-ranked_500

FBN1 EFEMP1 IGFBP6 SVEP1 SCN2A

6.71e-04408375gudmap_kidney_adult_RenalCapsule_500
CoexpressionAtlasDevelopingGonad_e18.5_epididymis_emap-13166_k-means-cluster#5_top-relative-expression-ranked_1000

ADGRB3 LTBP2 EFEMP1 MEGF6

7.14e-04234374gudmap_developingGonad_e18.5_epididymis_1000_k5
CoexpressionAtlasdev gonad_e11.5_M_GonadVasMes_Flk_top-relative-expression-ranked_500

SCUBE1 FBN1 EFEMP1 SVEP1 SCN2A

7.49e-04418375gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_500
CoexpressionAtlaskidney_P0_JuxtaGlom_Ren1_top-relative-expression-ranked_1000

LAMA5 FBN1 EFEMP1 AGRN JAG1 NOTCH3 SLIT3

8.38e-04905377gudmap_kidney_P0_JuxtaGlom_Ren1_1000
CoexpressionAtlasStromal Cells, Fi.Sk, gp38+ CD140a+, Skin, avg-4

FBN1 EFEMP1 IGFBP6 SVEP1 SLIT3

9.14e-04437375GSM777046_500
CoexpressionAtlaskidney_adult_RenalCapsule_k-means-cluster#3_top-relative-expression-ranked_200

EFEMP1 IGFBP6 SVEP1

9.25e-04110373gudmap_kidney_adult_RenalCapsule_k3_200
CoexpressionAtlasStromal Cells, Fi.MTS15+.Th, CD45- PDGFRa+ MTS15+, Thymus, avg-3

FBN1 EFEMP1 SVEP1 JAG1 SLIT3

9.91e-04445375GSM777043_500
CoexpressionAtlasdev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k-means-cluster#2_top-relative-expression-ranked_1000

SCUBE1 FBN1 SVEP1 SCN2A

1.13e-03265374gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k2_1000
CoexpressionAtlasProgenitor-Cell-Biology-Consortium_reference_CardiacMyocyte_top-relative-expression-ranked_1000

LTBP2 FBN1 EFEMP1 ADAMTS14 IGFBP6 SVEP1 SLIT3

1.29e-03975377PCBC_ctl_CardiacMyocyte_1000
CoexpressionAtlasdev lower uro neuro_e15.5_PelvicGanglion_Sox10_k-means-cluster#1_top-relative-expression-ranked_500

ADGRB3 SCN2A SLIT3

1.34e-03125373gudmap_dev lower uro neuro_e15.5_PelvicGanglion_Sox10_k1_500
ToppCell10x3'2.3-week_17-19-Mesenchymal_adipo-stroma|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

SCUBE1 LTBP2 FBN1 EFEMP1 IGFBP6 SVEP1 NOTCH3

3.12e-10197387b9745e382baa2725dfcae060701fb53f6c8a31fa
ToppCell10x3'2.3-week_17-19-Mesenchymal_adipo|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

SCUBE1 LTBP2 FBN1 EFEMP1 IGFBP6 SVEP1 NOTCH3

3.12e-101973875afddde4e2b5cd55abe11e9b9efae02dbdc3da3a
ToppCell10x3'2.3-week_17-19-Mesenchymal_adipo-stroma-adipo-CAR|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

SCUBE1 LTBP2 FBN1 EFEMP1 IGFBP6 SVEP1 NOTCH3

3.12e-101973871baffd087ca194a7355fefbb3bf67befb14fe2de
ToppCell10x5'v1-week_14-16-Mesenchymal_adipo-stroma|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

LTBP2 FBN1 EFEMP1 SVEP1 JAG1 NOTCH3 SLIT3

3.35e-101993879b2262edbdec89166d895ab97527e0ee5f9b6010
ToppCell10x5'v1-week_14-16-Mesenchymal_adipo|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

LTBP2 FBN1 EFEMP1 SVEP1 JAG1 NOTCH3 SLIT3

3.35e-10199387251b3643dcd8f4645b17101bd716e66f12a20e88
ToppCell10x5'v1-week_14-16-Mesenchymal_adipo-stroma-adipo-CAR|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

LTBP2 FBN1 EFEMP1 SVEP1 JAG1 NOTCH3 SLIT3

3.35e-10199387117f4f43b6c06dda553799b1063e827bce697370
ToppCelldistal-1-mesenchymal|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

LTBP2 FBN1 EFEMP1 IGFBP6 SVEP1 NOTCH3 SLIT3

3.47e-102003877623f82bd85a0ff7e2097e9281551208dfc602a8
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-24m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBLN7 FBN1 EFEMP1 IGFBP6 SVEP1 SLIT3

1.14e-08186386ff6ccfdf2509f96caa10281c29a95b432f6c6dcc
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LTBP2 FBN1 EFEMP1 IGFBP6 SVEP1 SLIT3

1.21e-08188386e18065bbc26d6f3774fd1f478fb41d8fb555fa26
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LTBP2 FBN1 EFEMP1 IGFBP6 SVEP1 SLIT3

1.25e-08189386d531399749409d614adca13d181830c6e3287508
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LTBP2 FBN1 EFEMP1 IGFBP6 SVEP1 SLIT3

1.33e-081913864e4488380379ed29d7898bae4e24221e7c67eb9d
ToppCellhuman_hepatoblastoma-Hepatic_Stellate_cells|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)

ADGRB3 FBN1 EFEMP1 JAG1 NOTCH3 SLIT3

1.33e-0819138678c3c2fdb68c3407f2436f90e1e6a780bbf8b79e
ToppCellCOVID-19-Heart-Fib_2|Heart / Disease (COVID-19 only), tissue and cell type

ADGRB3 LTBP2 FBN1 EFEMP1 IGFBP6 SVEP1

1.46e-08194386d91c9f2ec47319051fc398320693fddbe8bbd4d6
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LTBP2 FBN1 EFEMP1 IGFBP6 SVEP1 SLIT3

1.51e-08195386f54bc4454270ff06e85596f98199372b50d0179f
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.4.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LTBP2 FBN1 EFEMP1 IGFBP6 SVEP1 SLIT3

1.56e-08196386988a3e0688e0a7ba69774497d3b130631bb26c50
ToppCellnucseq-Mesenchymal-Fibroblastic|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ADGRB3 LTBP2 FBN1 IGFBP6 SVEP1 SLIT3

1.56e-081963867d8505dac15fa59935ccf592afc54b04c4c6554f
ToppCellCOPD-Stromal|COPD / Disease state, Lineage and Cell class

LTBP2 FBN1 EFEMP1 IGFBP6 SVEP1 SLIT3

1.60e-08197386d5390d86acaa8c39f1da893e8d2271f9ed2951d7
ToppCellnucseq-Mesenchymal|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ADGRB3 LTBP2 FBN1 IGFBP6 SVEP1 SLIT3

1.65e-081983868f52243ca8b9ba68a75ae411506a3a6de258eb97
ToppCellbackground-Hepatic_Stellate_cells|background / Sample and Cell Type and Tumor Cluster (all cells)

ADGRB3 LTBP2 FBN1 EFEMP1 SVEP1 JAG1

1.65e-08198386bd11b0e9e80449aab979a02c1023e0638c431c7c
ToppCell5'-Parenchyma_lung-Mesenchymal|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LTBP2 FBN1 EFEMP1 IGFBP6 SVEP1 SLIT3

1.65e-08198386aae663c6da70b6e716edeed50cc7d3962d78e697
ToppCellControl-Stromal|Control / Disease state, Lineage and Cell class

LTBP2 FBN1 EFEMP1 IGFBP6 SVEP1 SLIT3

1.65e-08198386ae726b6b7f0a4107899be4d32ac256ffa0bd8d59
ToppCellBronchus_Control_(B.)-Stromal-TX-Mesothelial-2|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

VWC2L SCUBE1 FBN1 SVEP1 SCN2A SLIT3

1.70e-0819938660a653100aff31f7f96796ff2ec634798bfb4b0d
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LTBP2 FBN1 EFEMP1 IGFBP6 SVEP1 SLIT3

1.70e-081993860019cfaa586a450c2e4952d1184a540561c8d0ba
ToppCellASK452-Mesenchymal-Fibroblast|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq

LTBP2 FBN1 IGFBP6 SVEP1 NOTCH3 SLIT3

1.70e-081993864d0bf2a4bd97e5a3bfe4570a201cc21bb9c4c1f6
ToppCellASK452-Mesenchymal|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq

LTBP2 FBN1 IGFBP6 SVEP1 NOTCH3 SLIT3

1.70e-0819938693e85e3731a9ece9aee3eb82c5dfdad331ee62d6
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LTBP2 FBN1 EFEMP1 IGFBP6 SVEP1 SLIT3

1.70e-081993864e128c705ad36fd840582848f278770f356fcc8b
ToppCellParenchymal-10x3prime_v2-Stromal|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

LTBP2 FBN1 EFEMP1 IGFBP6 SVEP1 SLIT3

1.76e-08200386f6be0f24e607abb9007823a54fb0b24d04990a89
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LTBP2 FBN1 EFEMP1 IGFBP6 SVEP1 SLIT3

1.76e-08200386933b5b400e48a511ba0a056be1d33d3610b5f10d
ToppCellcellseq-Mesenchymal|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

LTBP2 FBN1 IGFBP6 SVEP1 NOTCH3 SLIT3

1.76e-08200386238285fc372ce2e5e4341fc3084a3a833bf4a0a6
ToppCellParenchyma_Control_(B.)-Stromal-TX|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

LTBP2 FBN1 EFEMP1 IGFBP6 SVEP1 SLIT3

1.76e-082003860a86656d48e4238d0e4d592d477d29f7ba7c2ec0
ToppCellBiopsy_Other_PF-Mesenchymal-Fibroblasts|Biopsy_Other_PF / Sample group, Lineage and Cell type

FBN1 EFEMP1 IGFBP6 SVEP1 SCN2A SLIT3

1.76e-082003869996b6887cf2b1936e10a1aa396f09fd8da5f4c4
ToppCelldistal-mesenchymal|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

LTBP2 EFEMP1 IGFBP6 SVEP1 NOTCH3 SLIT3

1.76e-08200386b54137a4545690f51e154bb05964eaa650c3ca8e
ToppCell390C-Fibroblasts-Fibroblast-H-|390C / Donor, Lineage, Cell class and subclass (all cells)

LTBP2 FBN1 EFEMP1 IGFBP6 SVEP1 SLIT3

1.76e-08200386ec7d6a08e34bcad5b3bbff56ebef96ae17e4cefd
ToppCellBronchial-10x5prime-Stromal|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

LTBP2 FBN1 EFEMP1 IGFBP6 SVEP1 SLIT3

1.76e-082003865ea12e17f50fefbf5534e487af3392b2fa2d13ad
ToppCellBronchial-10x5prime-Stromal-Fibroblastic-Fibro_adventitial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

LTBP2 FBN1 EFEMP1 IGFBP6 SVEP1 SLIT3

1.76e-08200386b04831708fa20471a127b87e8db3728b6e729ce8
ToppCell343B-Fibroblasts|343B / Donor, Lineage, Cell class and subclass (all cells)

LTBP2 FBN1 EFEMP1 IGFBP6 SVEP1 SLIT3

1.76e-08200386376c1a77031e090be96948b47c78ac0d393f5775
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

LTBP2 FBN1 EFEMP1 IGFBP6 SVEP1 SLIT3

1.76e-082003863fa7d9ea67f9cc55478d085da53babd03dbe9bb1
ToppCellBronchial-10x5prime-Stromal-Fibroblastic|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

LTBP2 FBN1 EFEMP1 IGFBP6 SVEP1 SLIT3

1.76e-082003866316c288022719b9e6c4332c5cb9041e1188d0e8
ToppCell5'-Adult-Distal_Rectal-Mesenchymal|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LTBP2 FBN1 EFEMP1 IGFBP6 SVEP1 SLIT3

1.76e-08200386db6281b5d4032116310db379d9175d790994c99c
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Transitional_Stromal_3_(C3+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LTBP2 FBN1 EFEMP1 IGFBP6 SVEP1 SLIT3

1.76e-08200386cfea2f9d85646c9b722150551ff2e8fc4f6cc98a
ToppCellParenchymal-10x5prime-Stromal-Fibroblastic-Fibro_adventitial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

LTBP2 FBN1 EFEMP1 IGFBP6 SVEP1 SLIT3

1.76e-082003866b48ddde83bc6c941d557844aa214d4d2c8e736d
ToppCellParenchymal-10x3prime_v2-Stromal-Fibroblastic|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

LTBP2 FBN1 EFEMP1 IGFBP6 SVEP1 SLIT3

1.76e-08200386fd92d8250c6ad1e8bb46b303ac37f8dcf80387d8
ToppCell3'-Parenchyma_lung-Mesenchymal|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LTBP2 FBN1 EFEMP1 IGFBP6 SVEP1 SLIT3

1.76e-08200386ba5ed66b05caa1be0bbf8d54c4e72a782b8d9833
ToppCell5'-Adult-Distal_Rectal-Mesenchymal-fibroblastic-Transitional_Stromal_3_(C3+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LTBP2 FBN1 EFEMP1 IGFBP6 SVEP1 SLIT3

1.76e-08200386a2bb67a06757f19be3f56f8cb5bb7e2affa5f4ed
ToppCellParenchymal-10x5prime-Stromal|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

LTBP2 FBN1 IGFBP6 SVEP1 NOTCH3 SLIT3

1.76e-082003862e525c0d9684e7a2275edb04e1addb6fc6a872e5
ToppCellFibroblast|World / shred by cell class for parenchyma

LTBP2 FBN1 EFEMP1 IGFBP6 SVEP1 SLIT3

1.76e-08200386dec9ce1bc2571197003596f32e5f742ede72aa79
ToppCellLung_Parenchyma-Control-Mesenchymal|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

LTBP2 FBN1 EFEMP1 IGFBP6 SVEP1 SLIT3

1.76e-082003861e75d1302c22e1b1666c19c0c9259d5cc8be16d5
ToppCell390C-Fibroblasts-Fibroblast-H|390C / Donor, Lineage, Cell class and subclass (all cells)

LTBP2 FBN1 EFEMP1 IGFBP6 SVEP1 SLIT3

1.76e-08200386671e731977c58a0c44c36b56422085d93d999aad
ToppCellBiopsy_Other_PF-Mesenchymal|Biopsy_Other_PF / Sample group, Lineage and Cell type

LTBP2 FBN1 IGFBP6 SVEP1 NOTCH3 SLIT3

1.76e-08200386d6fcdd48858b53b5a8d18ae14b2dc4d9af41b070
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LTBP2 FBN1 EFEMP1 IGFBP6 SVEP1 SLIT3

1.76e-082003862e4ab7fbd94d3d865ef6188d3b4916d2bf1b8d89
ToppCell5'-Adult-LargeIntestine-Mesenchymal|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LTBP2 FBN1 EFEMP1 IGFBP6 SVEP1 SLIT3

1.76e-082003865a87bb8eb1c6bd2fbc357e1528e15ba1c0051438
ToppCell5'-Adult-Distal_Rectal-Mesenchymal-fibroblastic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LTBP2 FBN1 EFEMP1 IGFBP6 SVEP1 SLIT3

1.76e-0820038610f0c20ba7c71d9e2e177597f85b41cb40f0d878
ToppCelldistal-3-mesenchymal|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

LTBP2 EFEMP1 IGFBP6 SVEP1 NOTCH3 SLIT3

1.76e-082003867a79a2de78325d4f1c4535969106a0a44249028c
ToppCellChildren_(3_yrs)-Mesenchymal-chondrocyte-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

RASSF10 LTBP2 FBN1 SVEP1 SLIT3

2.29e-07158385e5636c0b608d68bd426a2b446ac508e4512e86a4
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LTBP2 FBN1 EFEMP1 IGFBP6 SVEP1

3.11e-071683854b2d29a7843bf45922038c093ca7ec0600756adc
ToppCell-Donor_05|World / lung cells shred on cell class, cell subclass, sample id

LTBP2 FBN1 IGHA1 SVEP1 SLIT3

3.20e-071693858ebe9a88111c53a09c25a7b6a164a0a17880458d
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PAPLN OTOGL NOTCH3 SLIT3 ADGRB1

3.29e-071703855570c0e825bca77613bf0ebde620cf744fa1cb84
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LTBP2 FBN1 EFEMP1 IGFBP6 SVEP1

3.39e-071713855d31fc9b60329d4ae3c77e4ca679359d9314397d
ToppCell343B-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)-|343B / Donor, Lineage, Cell class and subclass (all cells)

FBN1 EFEMP1 IGFBP6 SVEP1 SLIT3

3.91e-071763852e94bbe17c0bb65dc58b4ebc0cb829258bd7373b
ToppCell343B-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)|343B / Donor, Lineage, Cell class and subclass (all cells)

FBN1 EFEMP1 IGFBP6 SVEP1 SLIT3

3.91e-07176385f33ab41d121b59d871ad7d48ca021524a027d2ef
ToppCelldroplet-Bladder-nan-24m-Epithelial-nan|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBLN7 LTBP2 EFEMP1 IGFBP6 SLIT3

4.25e-07179385dfd9d29281510d32f1a2e8336d2e58ef496cfd1d
ToppCellBasal|World / shred by cell class for mouse tongue

JAG2 LAMA5 EFEMP1 MEGF6 AGRN

4.74e-07183385c6729a207526ff4aa48176207b9353176f631fea
ToppCellfacs-Mammary_Gland-Mammary_Gland-18m-Mesenchymal|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN1 EFEMP1 IGFBP6 SVEP1 SLIT3

4.74e-071833855cfcd589a480e67654d3d94e71916f122150db10
ToppCellfacs-Mammary_Gland-Mammary_Gland-18m-Mesenchymal-stromal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN1 EFEMP1 IGFBP6 SVEP1 SLIT3

4.74e-07183385c3ea8d3b916ffcaca3156e0d77a952724554c4ab
ToppCellfacs-Mammary_Gland-Mammary_Gland-18m-Mesenchymal-stromal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN1 EFEMP1 IGFBP6 SVEP1 SLIT3

4.74e-0718338581003ddc24164959dd41bb12fcac72638789b8f2
ToppCelldroplet-Lung-30m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RASSF10 LAMA5 FBN1 CPT1B MEGF6

4.87e-07184385f506d0ee48f39d6f59f19554217dfdf0987cc405
ToppCelldroplet-Lung-30m-Endothelial-arterial_endothelial|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RASSF10 LAMA5 FBN1 CPT1B MEGF6

4.87e-071843858bcb1c4bc8ffef74338cdade926a94711de93c64
ToppCellfacs-Mammary_Gland-Mammary_Gland-3m-Mesenchymal-stromal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN1 EFEMP1 IGFBP6 SVEP1 SLIT3

5.01e-071853853cd0686a14e734a0f243070ab939adcb4c454478
ToppCellfacs-Mammary_Gland-Mammary_Gland-3m-Mesenchymal-stromal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN1 EFEMP1 IGFBP6 SVEP1 SLIT3

5.01e-0718538500258f458cbf6d36449db95528a6b5038d731d2d
ToppCellfacs-Mammary_Gland-Mammary_Gland-3m-Mesenchymal|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN1 EFEMP1 IGFBP6 SVEP1 SLIT3

5.01e-07185385a94694e226856bc5b168464f52d76004145717a5
ToppCellCOVID-19-Heart-Fib_2|COVID-19 / Disease (COVID-19 only), tissue and cell type

ADGRB3 LTBP2 FBN1 IGFBP6 SVEP1

5.01e-071853858f95d8e591bf7379d13f5a0545b0cb49e2b1ab5d
ToppCellfacs-Limb_Muscle-Muscle_forelimb_and_hindlimb-18m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN1 EFEMP1 IGFBP6 SVEP1 SLIT3

5.14e-07186385a7ab70b049742dfe7ee30557031bfac6412edf52
ToppCellfacs-Heart-LA-24m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN1 EFEMP1 IGFBP6 SVEP1 SLIT3

5.14e-07186385ed0a91f47e77fe21d4c7678d0f2a7c5f97d63dda
ToppCellfacs-Lung-24m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l1|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FBN1 EFEMP1 CPT1B IGFBP6 SCN2A

5.14e-07186385827f2f2ddde315d1e5970dd56f906c555ec699af
ToppCellhuman_hepatoblastoma-Hepatic_Stellate_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

ADGRB3 FBN1 JAG1 NOTCH3 SLIT3

5.14e-07186385cb1fc4b9140666b43415e21c9b434dc9b144e9d0
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PAPLN LTBP2 FBN1 SVEP1 SLIT3

5.14e-071863855473283fb95cee556b1f6934cf72169b676b5bcc
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.4.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FBN1 EFEMP1 IGFBP6 SVEP1 SLIT3

5.14e-0718638507d94d5d1c2fe7bb909a07ca81058a0eabc65c60
ToppCellfacs-Heart-LA-24m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN1 EFEMP1 IGFBP6 SVEP1 SLIT3

5.28e-071873851669df899b1759c338ffce196fe009840123cfcd
ToppCelldroplet-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN1 EFEMP1 IGFBP6 SVEP1 SLIT3

5.28e-071873854e553721fa5598cb211f44e3226280b7e6885484
ToppCellfacs-Trachea-nan-24m-Mesenchymal|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN1 EFEMP1 IGFBP6 SVEP1 SLIT3

5.28e-0718738571385068e3fd0bfa7822ae176113a49460c8636b
ToppCelldroplet-Pancreas-Exocrine-18m-Mesenchymal|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN1 EFEMP1 IGFBP6 SVEP1 SLIT3

5.28e-07187385d36e7fc6125e7a4310499365022d38f34b757a73
ToppCellfacs-Trachea-nan-24m-Mesenchymal-fibroblast|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN1 EFEMP1 IGFBP6 SVEP1 SLIT3

5.28e-07187385b930d5f7d410ac1f340babec5c937388f64cafc0
ToppCelldroplet-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN1 EFEMP1 IGFBP6 SVEP1 SLIT3

5.28e-07187385827eae63fabf6892a82ce7779b5f395958d3d628
ToppCellwk_08-11-Mesenchymal-Myofibro_&_SMC-Vascular_SMC_1|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

LTBP2 MEGF6 JAG1 NOTCH3 SLIT3

5.28e-071873851aebf6fab40b96f2f5feb77a302bb805838fccf3
ToppCellLA-01._Fibroblast_I|World / Chamber and Cluster_Paper

ADGRB3 LTBP2 FBN1 IGFBP6 SVEP1

5.28e-071873854ea486991f66c29728d127171a07b81404ec0b78
ToppCellfacs-Heart-LA-24m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN1 EFEMP1 IGFBP6 SVEP1 SLIT3

5.28e-07187385f3ef3f5a761f8306edc39bf16e76e44aae6fa7f6
ToppCellfacs-Trachea-nan-24m-Mesenchymal-nan|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN1 EFEMP1 IGFBP6 SVEP1 SLIT3

5.28e-07187385e891e571f6bb9433a0046215de6cabd89ed1effc
ToppCellControl-Fibroblasts-Alveolar_FB|Control / group, cell type (main and fine annotations)

ADGRB3 LTBP2 FBN1 SVEP1 SLIT3

5.28e-0718738592d468dde81125d51daf7abd4703741abe1ab91c
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FBN1 MEGF6 IGFBP6 SVEP1 SLIT3

5.42e-07188385ce85a56ac27a6432421dde93a1bafa8b943244b9
ToppCellfacs-Lung-18m-Mesenchymal-fibroblast|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FBN1 EFEMP1 IGFBP6 SVEP1 SLIT3

5.56e-0718938540cbd679dc0548bf5207e1b033c0597886ad6fe1
ToppCellfacs-BAT-Fat-18m-Mesenchymal|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBLN7 FBN1 EFEMP1 IGFBP6 SLIT3

5.56e-07189385bba28f57a0708515fdd5acd9592dbbe4a4f57116
ToppCellfacs-BAT-Fat-18m-Mesenchymal-mesenchymal_progenitor|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBLN7 FBN1 EFEMP1 IGFBP6 SLIT3

5.56e-07189385cf293b23a4c0e8a0c9f09115b1d53d9b11de72e2
ToppCelldroplet-Lung-immune-endo-depleted|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN1 EFEMP1 IGFBP6 SVEP1 SLIT3

5.56e-07189385c3fb363bb0156ffb3367c200f548faebda64ab4a
ToppCellfacs-BAT-Fat-18m-Mesenchymal-mesenchymal_stem_cell_of_adipose|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBLN7 FBN1 EFEMP1 IGFBP6 SLIT3

5.56e-0718938587323e86a5b5d159920a07e6bd7ef5e3438cd085
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADGRB3 NELL1 FBN1 SVEP1 SLIT3

5.56e-071893852a22b9fae70afb3dab8476f9c00e48a4df756410
ToppCellfacs-Lung-18m-Mesenchymal|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FBN1 EFEMP1 IGFBP6 SVEP1 SLIT3

5.56e-07189385bdf8db938aa0863c4fed6fa99dcffd63c8c20c31
ToppCelldroplet-Lung-immune-endo-depleted-3m|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN1 EFEMP1 IGFBP6 SVEP1 SLIT3

5.56e-071893852a2953f6b1b7d070d739dcaf7285fce6e097d9e4
ToppCelldroplet-Lung-3m|Lung / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FBN1 EFEMP1 IGFBP6 SVEP1 SLIT3

5.56e-071893855a636e952da9b1fd26aa17f7b129054f2da322b5
ToppCelldroplet-Mammary_Gland-nan-21m-Mesenchymal-stromal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN1 EFEMP1 IGFBP6 SVEP1 SLIT3

5.56e-07189385bc54ffd7bd1627a36747a80ce5139e4a69928400
ToppCellfacs-GAT-Fat-24m-Mesenchymal|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN1 EFEMP1 IGFBP6 SVEP1 SLIT3

5.71e-071903853720e64129f3f3268b1dc14031a76f41c38241c2
ComputationalMetal / Ca ion binding.

NELL1 LTBP2 FBN1 EFEMP1 SLIT3

1.48e-06133175MODULE_324
ComputationalDRG (dorsal root ganglia) genes.

LAMA5 LTBP2 FBN1 IGFBP6 NOTCH3

2.46e-04384175MODULE_2
ComputationalNeighborhood of EPHA7

ADGRB3 NELL1 SCN2A

1.26e-03139173MORF_EPHA7
ComputationalAdhesion molecules.

LAMA5 NELL1 FBN1

1.31e-03141173MODULE_122
ComputationalNeighborhood of PTX3

FBN1 EFEMP1

1.44e-0336172GNF2_PTX3
ComputationalDevelopmental processes.

NELL1 FBN1 JAG1 SLIT3

1.56e-03333174MODULE_220
ComputationalOvary genes.

LTBP2 FBN1 IGFBP6 NOTCH3

2.26e-03368174MODULE_1
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

FBN1 IGFBP6

2.54e-0348172GAVISH_3CA_METAPROGRAM_FIBROBLASTS_PI16_POS
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

JAG1 NOTCH3

2.76e-0350172GAVISH_3CA_METAPROGRAM_FIBROBLASTS_PERICYTE_LIKE
ComputationalGenes in the cancer module 287.

FBN1 EFEMP1

2.76e-0350172MODULE_287
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

EFEMP1 IGFBP6

2.76e-0350172GAVISH_3CA_METAPROGRAM_FIBROBLASTS_COMPLEMENT
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

JAG2 JAG1

2.76e-0350172GAVISH_3CA_METAPROGRAM_ENDOTHELIAL_NOTCH_SIGNALING
ComputationalLung genes.

LAMA5 LTBP2 IGFBP6 NOTCH3

4.10e-03434174MODULE_5
ComputationalECM and collagens.

LTBP2 FBN1 NOTCH3

4.95e-03225173MODULE_47
ComputationalPlacenta genes.

LAMA5 LTBP2 JAG1 NOTCH3

5.17e-03463174MODULE_38
Druglead stearate

JAG2 IGFBP6 JAG1 NOTCH3

1.16e-0584384CID000061258
DrugMetoclopramide monohydrochloride [7232-21-5]; Down 200; 11.8uM; PC3; HT_HG-U133A

TRAF4 AGRN NOTCH1 ZNF783 NOTCH3

1.66e-051933854285_DN
Drugnordihydroguaiaretic acid; Down 200; 1uM; PC3; HT_HG-U133A

JAG2 LAMA5 NOTCH1 NOTCH3 NSD3

1.70e-051943851223_DN
DiseaseCarcinoma, Pancreatic Ductal

JAG2 NOTCH1 JAG1 NOTCH3

2.44e-0824384C0887833
DiseaseGlioblastoma

JAG2 NOTCH1 JAG1 NOTCH3

3.28e-0679384C0017636
DiseaseGiant Cell Glioblastoma

JAG2 NOTCH1 JAG1 NOTCH3

4.19e-0684384C0334588
DiseaseWeill-Marchesani syndrome

LTBP2 FBN1

4.84e-063382C0265313
DiseaseWeill-Marchesani Syndrome, Autosomal Dominant

LTBP2 FBN1

4.84e-063382C1869115
DiseaseWeill-Marchesani Syndrome, Autosomal Recessive

LTBP2 FBN1

4.84e-063382C1869114
Diseasepulse pressure measurement

LAMA5 LTBP2 FBN1 EFEMP1 MEGF8 SVEP1 JAG1 NOTCH3 NSD3 SLIT3

7.44e-0613923810EFO_0005763
DiseaseWeill-Marchesani syndrome

LTBP2 FBN1

9.67e-064382cv:C0265313
DiseaseWeill-Marchesani syndrome (is_implicated_in)

LTBP2 FBN1

9.67e-064382DOID:0050475 (is_implicated_in)
DiseaseGlioblastoma Multiforme

JAG2 NOTCH1 JAG1 NOTCH3

1.27e-05111384C1621958
Diseaseadenocarcinoma (implicated_via_orthology)

NOTCH1 NOTCH3

3.38e-057382DOID:299 (implicated_via_orthology)
Diseasecentral nervous system cancer (implicated_via_orthology)

NOTCH1 NOTCH3

3.38e-057382DOID:3620 (implicated_via_orthology)
DiseaseFamilial thoracic aortic aneurysm and aortic dissection

FBN1 NOTCH1 JAG1

4.42e-0553383C4707243
DiseaseMarfan Syndrome

LTBP2 FBN1

8.82e-0511382C0024796
Diseasedilated cardiomyopathy (implicated_via_orthology)

JAG2 LTBP2 JAG1

1.51e-0480383DOID:12930 (implicated_via_orthology)
Diseasebipolar disorder, sex interaction measurement

SLIT3 ADGRB1

2.44e-0418382EFO_0008343, MONDO_0004985
Diseasecortical surface area measurement

JAG2 NELL1 SCUBE1 FBN1 ZAN MEGF6 SVEP1 JAG1

2.63e-041345388EFO_0010736
Diseasecongenital heart disease (is_implicated_in)

NOTCH1 JAG1

4.38e-0424382DOID:1682 (is_implicated_in)
Diseasesystemic mastocytosis

EYS MEGF6

4.75e-0425382MONDO_0016586
Diseasebrain cancer (implicated_via_orthology)

NOTCH1 NOTCH3

5.15e-0426382DOID:1319 (implicated_via_orthology)
DiseaseMammary Carcinoma, Human

JAG2 EFEMP1 NOTCH1 JAG1 NOTCH3

5.41e-04525385C4704874
DiseaseMammary Neoplasms, Human

JAG2 EFEMP1 NOTCH1 JAG1 NOTCH3

5.41e-04525385C1257931
DiseaseMammary Neoplasms

JAG2 EFEMP1 NOTCH1 JAG1 NOTCH3

5.50e-04527385C1458155
DiseaseBreast Carcinoma

JAG2 EFEMP1 NOTCH1 JAG1 NOTCH3

6.04e-04538385C0678222
Diseasecolorectal cancer (implicated_via_orthology)

NOTCH1 NOTCH3

6.87e-0430382DOID:9256 (implicated_via_orthology)
Diseaseintestinal cancer (implicated_via_orthology)

NOTCH1 NOTCH3

7.82e-0432382DOID:10155 (implicated_via_orthology)
Diseasebody weight

ADGRB3 NELL1 EYS LTBP2 EFEMP1 ADAMTS14 SLIT3

1.01e-031261387EFO_0004338

Protein segments in the cluster

PeptideGeneStartEntry
GPQDEYRQCGTQRCP

ADGRB1

561

O14514
RCNEQRCPAPYEICP

ADGRB3

501

O60242
GDTVIPLYIPQCGEC

ADH5

86

P11766
CVPREAAYVCLCPGG

AGRN

1836

O00468
PYSVCARGECVPVGC

ADAMTS14

676

Q8WXS8
QGMLCGPPQCYCIVE

RASSF10

81

A6NK89
CVEGVNQYRCICPPG

FBLN7

151

Q53RD9
ACVDGVNTYNCRCPP

NOTCH1

271

P46531
CIDQPGNYFCQCVPP

EYS

696

Q5T1H1
NDCNPLPCYNGGICV

JAG2

791

Q9Y219
YDCVCQPGFTGPLCN

NOTCH3

641

Q9UM47
PVCAQGCVNGSCVEP

MEGF8

2221

Q7Z7M0
VPCLNDCGPYGQCLL

PGAP6

496

Q9HCN3
PGVCDPLTGQCYCKE

LAMA5

1586

O15230
CVNLPGLYRCDCVPG

NELL1

451

Q92832
QQVPVACKSCPCGYI

C16orf87

21

Q6PH81
VRYLCQNGRCIPTPG

FBN1

456

P35555
VQGPPERDLCGCYSV

IGHA1

171

P01876
CVNLPDGYRCVCSPG

LTBP2

861

Q14767
RCLNTVPGYVCLCNP

LTBP2

1501

Q14767
VICVNYLVGFCPEGP

CPSF4

146

O95639
CIRCPVGTYQPEFGQ

SCUBE1

756

Q8IWY4
REGQECGVYTPNCAP

IGFBP6

66

P24592
CIQRCLPQGCGPYQT

CPT1B

86

Q92523
CPEGKEYQPCVRPCE

OTOGL

1806

Q3ZCN5
VDEINGYRCVCPPGH

JAG1

836

P78504
CEAGYVGPRCEQQCP

MEGF6

891

O75095
CPPGYQKRGEQCVDI

EFEMP1

201

Q12805
VCRFPCQNGGICQRP

SVEP1

3471

Q4LDE5
LPCLNGGRCVAPYQC

SVEP1

3506

Q4LDE5
CVDGINNYVCICPPN

SLIT3

1011

O75094
YCCQLVGGVLVEQCP

PEX11G

26

Q96HA9
NLCTCPYGFVGPRCE

VWDE

1376

Q8N2E2
GVRCQIPICNPKCLY

VWDE

1546

Q8N2E2
APCQQSRYGCCPDRV

PAPLN

656

O95428
QCPEGYICVKAGRNP

SCN2A

346

Q99250
QYQCPRLPVACPNQC

TRAF4

211

Q9BUZ4
YECHPQVCPAGDRCQ

NSD3

1121

Q9BZ95
VYEPEQCCPVCKNGP

VWC2L

161

B2RUY7
RIHTGERPYQCPQCG

ZNF783

486

Q6ZMS7
PSACAEGCICQPGYV

ZAN

2241

Q9Y493